Ministero della Salute Direzione Generale Ricerca Sanitaria e Biomedica e della Vigilanza sugli Enti BANDO 2010 GIOVANI RICERCATORI e RICERCA FINALIZZATA Tutte le Sezioni 2320870 RODDI New Robotic Platform for Rehabilitation of Children with Pervasive Developmental Disorders and Cognitive Impairments. CARLO BESTA CLI Biobehavioral and Behavioral Processes 4 222.900 2306996 Multipotent Stem/Progenitor Cells in Human Extrahepatic Biliary Tree: isolation, culturing, differentiation in vitro and in vivo, identification of intracellular pathways modulating proliferation and differentiation and development of strategies for the t Marche Digestive, Kidney and Urological Systems 4,5 195.400 2312984 Role of morgana/chp 1 in myeloproliferative disorders Piemonte Oncology 1 Basic 4,5 276.700 2309719 EMILIN1 in tumor microenvironment: role in neoplastic growth and lymphatic spread C.R.O. AVIANO Oncology 1 Basic 4,5 272.600 2310494 mir 221&222/miR 126&126* interconnected networks: novel molecular markers and potential therapeutic values in melanoma. Istituto Superiore di Sanita' Oncology 1 Basic 4,5 336.600 2318823 Toward Chronic Lymphocytic Leukemia (CLL): dissecting the role of genetic lesions in Monoclonal B cell Lymphocytosis (MBL) through a genome wide sequencing approach Oncology 1 Basic 4,5 412.800 2314291 Role of circulating and tissutal markers of low grade chronic inflammation for defining the clinical phenotype of complicated obesity MAUGERI CLI Endocrinology, Metabolism, Nutrition and Reproductive Sciences 4,5 254.300 Pagina 1 di 31
2309622 Definition of mechanisms controlling processing and secretion of IL 1beta in health and autoinflammatory diseases, search for novel therapeutic strategies IRCCS AOU San Martino IST (Genova) Immunology 4,5 481.700 2317594 NEW GENETIC LESIONS CHARACTERIZING HIGH RISK CHRONIC LYMPHOCYTIC LEUKEMIA: CLINICAL AND FUNCTIONAL IMPLICATIONS Piemonte EST Oncology 2 4,5 500.000 2318269 Exploiting immune cross reactivity to influenza viral antigens for successful pre pandemic vaccines. Istituto Superiore di Sanita' Immunology 5 454.800 2313979 strategy for developing rationale combinations of molecularly targeted agents in primary refractory Hodgkin lymphoma Piemonte CLI Oncology 2 5 500.000 2316156 Immunotherapy with dendritic cells loaded with cancer stem like cells: a phase I study in glioblastoma CARLO BESTA CLI Oncology 2 5 320.800 2310201 Plasma microrna profiling as first line screening test for lung cancer detection: a prospective study ISTITUTO TUMORI MILANO CLI Oncology 2 5 358.400 2319316 High density EEG as a tool for localizing the epileptogenic zone in extratemporal refractory focal epilepsy: a validation study by means of Stereo EEG and post surgical outcome evaluation Lombardia CLI EST Brain Disorders and 5 306.600 2310888 TUMOR ASSOCIATED MACROPHAGES: NEW MARKERS FOR MOLECULAR TARGETING HUMANITAS Oncology 1 Basic 5 454.800 2310438 PROTECTIVE AND DANGEROUS IMMUNE RESPONSES DURING HIV 1 INFECTION OSPEDALE BAMBINO GESU' CLI EST AIDS and Related Research 5 401.100 2319050 Gene therapy for thalassemia: preclinical studies of efficacy and safety Genes, Genomes and Genetics 5 432.500 2311657 Recovery of cholinergic neurotransmission dysfunction in DYT1 dystonia SANTA LUCIA Brain Disorders and 5 320.800 Pagina 2 di 31
2312222 The role of hypoxia in regulating micrornas and target genes in cancer biology: identification of new therapeutic targets Istituto Superiore di Sanita' Oncology 1 Basic 5 451.800 2312785 Therapeutic potential and safety assessment of induced dopaminergic neuronal (idan) cells directly reprogrammed from adult skin fibroblasts Molecular, Cellular, and Developmental Neuroscience 5 454.800 2305041 Impaired Angiogenesis: a Novel Player and Potential Therapeutic Target in Muscular Dystrophy Istituto Superiore di Sanita' Musculoskeletal, Oral 5 454.800 2320280 Characterization of the histone deacetylase SIRT1 in human Non Hodgkin Lymphomas and lymph nodes. ARCISPEDALE Oncology 1 Basic 5 175.600 2309484 STUDIES ON THE INVOLVEMENT OF GENETIC, EPIGENETIC AND ENVRINOMENTALFACTORS IN THE PATHOGENESIS OF CONGENITAL HYPOTHYROIDISM.NOVEL PERSPECTIVES FOR THE MANAGEMENT OF A LARGELY UNEXPLAINED DISER AUXOLOGICO Endocrinology, Metabolism, Nutrition and Reproductive Sciences 5 454.800 2314703 Role of Nuclear Receptor Coactivator PGC1 beta in the Intestinal Epithelium ONCOLOGICO DI BARI Endocrinology, Metabolism, Nutrition and Reproductive Sciences 5,25 454.800 2310538 Building a state of the art whole room indirect calorimeter, a tool to accurately investigate the role of energy expenditure and substrate oxidation in endocrine and metabolic disorders Toscana Endocrinology, Metabolism, Nutrition and Reproductive Sciences 5,25 454.800 2319722 Italian Network for autosomal dominant Alzheimer s disease and frontotemporal lobar degeneration FATEBENEFRATELLI Brain Disorders and 5,25 454.800 2311584 Thrombolysis in Minor Stroke Emilia Romagna CLI Brain Disorders and 5,5 245.400 2318290 Volatile anesthetics to reduce mortality in cardiac surgery. A multicentre randomized controlled study. CLI Surgical Sciences, Biomedical Imaging, and Bioengineering 5,5 500.000 Pagina 3 di 31
2308451 The Renal Damage Risk Study in children with Vesico Ureteral Reflux grade III to V Emilia Romagna CLI Digestive, Kidney and Urological Systems 5,5 500.000 2313899 Biomolecular and functional analysis of pathogenetic mechanisms of neuropathic pain in genetic and acquired small fibre neuropathies. Istituto Scienze Neurologiche Molecular, Cellular, and Developmental Neuroscience 5,5 362.200 2310812 Effect of supervised exercise training on risk of fractures in subjects with type 2 diabetes Lazio CLI Endocrinology, Metabolism, Nutrition and Reproductive Sciences 5,5 164.200 2320172 Assessment of short and long term risk benefit profile of biologics through healthcare database network in Italy Sicilia CLI Population Sciences and Epidemiology 5,5 272.900 2318372 Novel surface and intracellular targets for tailored nanotechnology based drug delivery in colorectal cancer SDN EST Oncology 1 Basic 5,5 410.000 2318508 Modulation of metabolic mechanisms in muscle loss disorders: involvement of autophagy and apoptosis. SAN RAFFAELE PISANA Musculoskeletal, Oral 5,5 386.600 2310935 Oculo auriculo vertebral spectrum: use of an integrated high throughput platform to identify the disease causing genes and implications in clinical diagnostics CASA SOLLIEVO SOFFERENZA Genes, Genomes and Genetics 5,5 215.000 2319394 A multidisciplinary study to investigate the molecular bases of hereditary tubulointerstitial nephritis Digestive, Kidney and Urological Systems 5,5 451.500 2314356 IDENTIFICATION OF GENES FOR RARE DEVELOPMENTAL DISERS BY NEXT GENERATION SEQUENCING GASLINI Genes, Genomes and Genetics 5,5 451.500 2308334 NEW THERAPEUTICS AND IMMUNOGENS GENERATED BY INCORPORATING SHORT RNAs AND PROTEIN ANTIGENS IN EXOSOMES Istituto Superiore di Sanita' Bioengineering Sciences and Technologies 5,5 451.500 2304056 Neuropsychological, neurofunctional and epigenetic effects of structured group patient education in type 2 diabetes. Piemonte CLI Endocrinology, Metabolism, Nutrition and Reproductive Sciences 5,75 150.000 Pagina 4 di 31
2317761 TRANSLATING MELANOMA EPIGENETICS IN THE CLINICAL SETTING OF COMBINED CHEMO IMMUNOTHERAPIES Toscana Oncology 2 5,9 386.600 2316780 Humanized tumor mice: a new model that improves translational biomedical research to develop new personalized therapies in ovarian cancer. PASCALE Oncology 1 Basic 6 372.100 2321718 Cognitive efficiency and functional connectivity across the lifespan. Is there a signature of abnormal cognitive decline? S.CAMILLO Brain Disorders and 6 197.400 2317822 "Epigenetic mechanisms in the control of viral transcription/replication in chronic HBV patients antiviral treatments: an integrated approach to the new biomarkers identification and rational clinical decisions. MAGGIORE Digestive, Kidney and Urological Systems 6 150.000 2300447 CANDIDATE PREDICTORS OF GLUCOCORTICOID RESPONSE IN CHILDREN WITH INFLAMMATORY BOWEL DISEASE BURLO GAROFALO CLI Digestive, Kidney and Urological Systems 6 193.300 2319274 In vivo confocal microscopy of corneal nerves as a novel diagnostic tool in peripheral neuropathies: correlation with skin biopsy, neurophysiology and clinical findings. Lombardia CLI Brain Disorders and 6 150.000 2310832 Role of TNF related apoptosis inducing ligand (TRAIL) in diabetes mellitus and metabolic syndrome BURLO GAROFALO CLI Endocrinology, Metabolism, Nutrition and Reproductive Sciences 6 249.200 2311484 Repetitive TMS modulation of the default mode network to clarify the pathophysiology of Alzheimer s disease and prompt a new therapeutic perspective SANTA LUCIA CLI Brain Disorders and 6 418.800 2314711 THE ITALIAN REGISTRY FOR MYOTONIC DYSTROPHIES SAN DONATO CLI Population Sciences and Epidemiology 6 193.300 2306232 Identification and functional validation of microrna biomarkers in lung cancer ISTITUTO TUMORI MILANO EST Oncology 2 6 271.500 Pagina 5 di 31
2321151 PHASE I/II TRIAL OF NOGA GUIDED ENDOCAVITARY INJECTION OF BONE MARROW DERIVED CD133+ CELLS IN ISCHEMIC REFRACTORY CARDIOMYOPATHY (RECARDIO TRIAL) MONZINO CLI Cardiovascular and Respiratory Sciences 6 296.900 2321465 RH Project: Advanced Serological and Molecular Investigation for the RhD Variants Definition Lazio Cell Biology 6 211.600 2312620 IL 6 related inflammation signatures as a predictive marker of recurrence in liver cancer patients ISTITUTO TUMORI MILANO CLI Oncology 2 6 387.300 2312048 THE IRON INFLAMMATION LIPID CONNECTION REVEALED BY HEPCIDIN REGULATION STUDIES: RELEVANCE FOR THE CORRESPONDING CLINICAL DISERS Vascular and Hematology 6 372.100 2316961 Molecular mechanisms underlying the skin inflammation triggered by Epidermal Growth Factor inhibitors and search for molecular targets for its correction ISTITUTO DERMOPATICO DELL'IMMACOLATA Musculoskeletal, Oral 6 247.200 2309921 IS DES ACYL GHRELIN THE KEY MEDIATOR OF KETOGENIC DIET? Emilia Romagna Brain Disorders and 6 332.500 2312059 Separation anxiety, CO2 Hypersensitivity and Panic: Epigenetic Mechanisms in Response to Adversities in Animal and Man Population Sciences and Epidemiology 6 372.100 2317808 Improving balance through gravity cues embedded in free falling target SANTA LUCIA Biobehavioral and Behavioral Processes 6 337.600 2314610 Relevance of the CD4+ T lymphocytes and synoviocytes cross talk in the pathogenesis of human rheumatoid arthritis and juvenile idiopathic arthritis diseases. Toscana Immunology 6 339.600 2305128 FSHD muscular dystrophy: molecular pathogenesis and prospects for therapy. Genes, Genomes and Genetics 6 372.100 Pagina 6 di 31
2306943 Development and preclinical validation of a nanotechnological platform that targets the minimal residual disease (MRD) in Cancer Calabria Oncology 2 6 372.100 2307403 Congenital anomalies of the kidney and urinary tract (CAKUT): definition of genetic and structural backgrounds based on high through put innovative approaches. GASLINI EST Digestive, Kidney and Urological Systems 6 244.100 2303119 B7.1 on podocytes: a new therapeutic target for diabetic nephropathy Digestive, Kidney and Urological Systems 6 372.100 2314035 Mechanisms of neurodegeneration and phenotypic heterogeneity in inherited prion diseases: physiopathological involvement of prion proteins in membrane trafficking and signaling Lombardia Brain Disorders and 6 318.300 2312912 And yet they MOve: immobile patients re enter the physical world through embodiment in avatar or robot surrogates SANTA LUCIA Biobehavioral and Behavioral Processes 6 372.100 2312924 Neuroinflammation and synaptic function: an electrophysiological analysis in experimental multiple sclerosis Umbria Brain Disorders and 6 197.400 2319328 Transcranial direct current stimulation in the treatment of dyslexia: a randomized double blind study OSPEDALE BAMBINO GESU' Brain Disorders and 6 260.400 2319511 Insulin resistance and cancer:new strategies of intervention involving the insulin receptor isoform A Sicilia Endocrinology, Metabolism, Nutrition and Reproductive Sciences 6 343.700 2315970 Nurr1 puts a dampener on inflammation: a link between Nurr1 deregulation and Multiple Sclerosis. Piemonte Brain Disorders and 6 251.200 Pagina 7 di 31
2318394 Autosomal Recessive Juvenile Parkinsonism (ARJP) caused by mutation in the PARK2 gene: Identification of the molecular mechanisms by which parkin can modify GluK2 activity and investigation of GluK2 as new target for a neuroprotective therapy AUXOLOGICO Brain Disorders and 6 451.200 2309531 Perivascular adipose tissue mirnas: links between insulin resistance in type 2 diabetes and vascular disease ISTITUTO DERMOPATICO DELL'IMMACOLATA Endocrinology, Metabolism, Nutrition and Reproductive Sciences 6 343.700 2310674 Standardizing tissue handling in pre analytical procedures: technological, environmentally safe innovation in solid tumour processing. Piemonte CLI COF Healthcare Delivery 6 150.000 2318330 Epigenetic drugs for human diabetic foot ulcer treatment ISTITUTO DERMOPATICO DELL'IMMACOLATA Musculoskeletal, Oral 6 372.100 2305199 Autophagy in the immune response against Mycobacterium tuberculosis: identification of novel rapamycin regulated host targets to improve BCG vaccine immunogenicity. Istituto Superiore di Sanita' EST Infectious Diseases and Microbiology 6 343.700 2318367 Biomarkers and functional imaging guided treatment decision making in recurrent prostate cancer. Toscana CLI EST Oncology 2 6 322.300 2321362 Phenotyping COPD patients and assessing disease severity by means of a standardized model Toscana CLI Cardiovascular and Respiratory Sciences 6,25 150.000 2306432 Generation and characterization of an anticd56 IL15 immunocytokine for functional reconstitution of NK cells in HIV infection Istituto Superiore di Sanita' AIDS and Related Research 6,25 451.200 2312522 Amyotrophic lateral sclerosis (ALS) swine models: production and characterization Sperimentale del Piemonte, Liguria e Valle d'aosta Brain Disorders and 6,25 451.200 Pagina 8 di 31
2316198 PATHWAYS OF COAGULATION AND PLATELET ACTIVATION IN FLOWING BLOOD: NEW PERSPECTIVES IN THE MANAGEMENT OF ANTITHROMBOTIC THERAPY C.R.O. AVIANO EST Vascular and Hematology 6,25 359.900 2306756 MitoCure: developing treatments for mitochondrial diseases CARLO BESTA Genes, Genomes and Genetics 6,25 451.200 2313809 MECHANISMS OF VASCULAR DYSFUNCTION IN OBESITY RELATED METABOLIC SYNDROME. Lazio CLI Vascular and Hematology 6,25 154.700 2311148 The use of OXT as adjunctive therapy for the treatment of schizophrenia: a randomized, double blind trial FATEBENEFRATELLI CLI Biobehavioral and Behavioral Processes 6,25 428.900 2311329 Dissection of the immune response to human cytomegalovirus glycoprotein complexes: perspective for the development of a candidate subunit vaccine SAN MATTEO EST Immunology 6,33 305.100 2309849 Genotype phenotype characterization of the pathogenetic expansion of the C9ORF72 gene in a large series of Italian familial and sporadic ALS patients Piemonte CLI Brain Disorders and 6,5 253.700 2313609 BCR ABL specific T cell Infusion for the Treatment of Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia Emilia Romagna CLI Oncology 2 6,5 497.300 2316010 P2X7 receptor/mmp9 pathway in thrombosis and atherosclerotic plaque destabilization: exploring the possibility to modulate carotid plaque progression EST Vascular and Hematology 6,5 376.600 2306851 Genetics of Hearing loss: from basic research to clinical applications BURLO GAROFALO CLI Genes, Genomes and Genetics 6,5 221.200 2313220 Mapping progressive neurodegeneration in amyotrophic lateral sclerosis (ALS): a multiparametric study combining clinical, cognitive, genetic, and neuroimaging assessment to identify predictors of ALS evolution CLI Brain Disorders and 6,5 497.300 Pagina 9 di 31
2310623 A PERSONALIZED MEDICAL APPROACH TO TREAT BACTERIAL INFECTIONS IN PATIENTS WITH LIVER CIRRHOSIS. Emilia Romagna CLI Digestive, Kidney and Urological Systems 6,5 192.700 2319806 CAPNAF FD. A Computer Assisted Procedure for Nasal Air Flow assessment with modern Fluid Dynamics techniques. Clinical applications: individual surgical planning of nasal breathing difficulties treatment aimed at optimizing surgical procedures towards max Lombardia CLI Surgical Sciences, Biomedical Imaging, and Bioengineering 6,5 150.000 2305605 Mechanisms of aggregation and toxicity of tau protein in Alzheimer's disease IRCCS AOU San Martino IST (Genova) EST Molecular, Cellular, and Developmental Neuroscience 6,5 356.300 2319059 Preparatory, response related, outcome evaluation and predictive components of attentional orienting in right brain damage: clues for diagnosis and rehabilitation SANTA LUCIA CLI EST Biobehavioral and Behavioral Processes 6,5 274.000 2309704 Targeting drug resistance in Ovarian Cancer C.R.O. AVIANO EST Oncology 2 6,5 370.500 2312693 Role of HMGB1 redox state in cardiac tissue regeneration and cardiac progenitor cell function MONZINO Cardiovascular and Respiratory Sciences 6,5 450.600 2304833 Novel markers based on autophagy proteins in Parkinson's disease NEUROMED CLI Brain Disorders and 6,5 256.700 2314794 Pancreas transplantation in type 1 diabetic patients revealed a potential novel stem cell based mechanism that revert diabetic enteropathy CLI Digestive, Kidney and Urological Systems 6,5 497.300 2312442 The Restless Mind: Default Mode Of Operation Or Risk Factor For Health? SANTA LUCIA Biobehavioral and Behavioral Processes 6,5 319.700 2317029 INTEGRATED ''OMIC'' APPROACH TO EXPLORE MOLECULAR PATHOGENESIS AND CLINICAL HETEROGENEITY IN FACIO SCAPULO HUMERAL MUSCULAR DYSTROPHY STELLA MARIS Musculoskeletal, Oral 6,5 232.300 Pagina 10 di 31
2309229 Spinal Muscular Atrophy with Respiratory Distress (SMARD1): gene therapy as novel therapeutic approach MAGGIORE Genes, Genomes and Genetics 6,5 269.900 2319033 Role of the Wnt/beta catenin pathway in orchestrating epigenetic events in Cancer Stem Cells Toscana Genes, Genomes and Genetics 6,5 428.300 2315964 The ubiquintin editing enzyme A20 (TNFAIP3) as a peacekeeper in inflammation and immunity: a link between TNFAIP3 deregulation and Multiple Sclerosis Piemonte Brain Disorders and 6,5 262.800 2319387 Impact of lincrnas on high serous ovarian cancer C.R.O. AVIANO Oncology 1 Basic 6,5 299.400 2315681 Assessment of safety parameters in cultured mesenchymal stromal cells for use in regenerative medicine. Sperimentale della Lombardia e dell'emilia Veterinary 6,5 256.700 (5) 2320533 Production and characterization of clinical grade stem cellderived conditioned medium for treatment of ischemic heart disease. SAN MATTEO Cardiovascular and Respiratory Sciences 6,5 450.600 2315414 mtor dependent oscillatory metabolic switch controlling self immune tolerance SANTA LUCIA EST Immunology 6,75 390.800 2313174 Brain plasticity in Alzheimer Disease and Mild Cognitive Impairment. Functional, structural and neuropsychological effects of a computer based cognitive treatment SANTA LUCIA CLI Brain Disorders and 7 245.340 2312173 Anterior Cruciate Ligament Reconstruction: biomechanical modeling for treatment selection to prevent Osteoarthritis RIZZOLI CLI Musculoskeletal, Oral 7 315.440 2317168 Prognostic value of a combined panel of soluble and genetic biomarkers in patients with early arthritis RIZZOLI CLI Musculoskeletal, Oral 7 322.540 2318689 Extracorporeal Life Support in Acute Respiratory Distress Syndrome (ELSA) Lombardia CLI Cardiovascular and Respiratory Sciences 7 241.340 Pagina 11 di 31
2320779 Role of peripheral Schwann cells and muscle in the regeneration of degenerated nerve terminals at the neuromuscular junction. Veneto Brain Disorders and 7 281.940 2319113 GRID based System for the Evaluation of the effects of Cognitive Rehabilitation in Patients with Alzheimer s Disease and Parkinson s Disease SAN RAFFAELE PISANA CLI Brain Disorders and 7 241.340 2304834 Idiopathic epilepsy: search for new mutations in HCN ion channels CARLO BESTA Brain Disorders and 7 370.340 2317709 Improving strategies for preventing pertussis in infants OSPEDALE BAMBINO GESU' CLI Infectious Diseases and Microbiology 7 386.540 2304957 FEEDING LOW GRADE INFLAMMATION AND INSULIN RESISTANCE OF THE FOETUS OSPEDALE BAMBINO GESU' Endocrinology, Metabolism, Nutrition and Reproductive Sciences 7 424.140 2314972 Brain and cognitive dynamics of multiple object processing in normal aging, MCI and Alzheimer disease FATEBENEFRATELLI Biobehavioral and Behavioral Processes 7 362.240 2310098 Mutations in ANKRD26 cause a novel inherited thrombocytopenia at risk of developing acute leukemia: dissecting the clinical and molecular consequences of ANKRD26 mutations to better understand the mechanisms of both thrombocytopenia and leukemia SAN MATTEO CLI Genes, Genomes and Genetics 7 281.940 2316392 New nuclear genes responsible for mitochondrial disorders: identification by high throughput exome sequencing and functional characterization of the corresponding proteins CARLO BESTA Genes, Genomes and Genetics 7 304.340 2309954 Reorganization of cortical function after surgery for lesional epilepsy in children Toscana CLI Brain Disorders and 7 200.740 2307975 Micro RNAs regulated by the proto oncogene Pbx1 as therapeutic targets to induce differentiation of cancer cells HUMANITAS Oncology 2 7 424.140 Pagina 12 di 31
2321454 The role of IG20, a novel human gene, and its potential use as therapeutic target in the anaplastic thyroid cancer. Toscana Endocrinology, Metabolism, Nutrition and Reproductive Sciences 7 200.740 2312868 Role of ATM kinase in ErbB2 signaling: a novel therapeutic target to hit ErbB2 positive breast cancer stem cells? SANTA LUCIA Oncology 2 7 322.540 2312573 MULTITHERAPEUTIC APPROACH TO THE SPINAL C INJURY BYSMART HYDROGEL DELIVERY MAGGIORE Brain Disorders and 7 424.140 2321017 Adipose Derived Stem Cells (ADSCs) in Suspension: Phenotyping, Differentiation and Engineering for Cranial Vault Reconstruction. Sicilia Surgical Sciences, Biomedical Imaging, and Bioengineering 7 244.340 2301676 The effects of diabetic autonomic neuropathy on postischemic bone marrow mobilization of endothelial progenitor cells. A translational study focusing on the role of Sirtuin 1 Veneto Vascular and Hematology 7 216.940 2305526 TArgeted Multistage vector (MSV) for the DIagnosis and treatment of Solid tumors Veneto EST Bioengineering Sciences and Technologies 7 252.540 2314890 SALUTE CKD (SALt lowering by Urine sodium selfmeasurement Trial in Chronic Kidney DiseasE) Calabria CLI Risk, Prevention and Health Behavior 7 443.340 2317597 Identification of common biological pathways in Rett patients mutated in MECP2, CDKL5 and FOXG1. Toscana EST Molecular, Cellular, and Developmental Neuroscience 7 248.440 2310869 Overcoming the postmitotic state of terminally differentiated cells in favor of regenerative medicine Istituto Superiore di Sanita' EST Musculoskeletal, Oral 7 205.740 2305957 Enhancement of models for identification of patients with potential benefit from chronic care case/disease management programs. Emilia Romagna CLI EST Healthcare Delivery 7 150.140 2306205 Noncoding RNAs and cancer IRCCS AOU San Martino IST (Genova) EST Oncology 1 Basic 7 164.140 Pagina 13 di 31
2318512 Role of influenza virus infection in the etiopathogenesis of diabetes Sperimentale delle Venezie EST Infectious Diseases and Microbiology 7 248.440 2309790 Pemphigus vulgaris as a paradigm of autoantibodymediated organ specific autoimmune disorder: pathophysiology and novel tools for diagnosis and therapy ISTITUTO DERMOPATICO DELL'IMMACOLATA EST Musculoskeletal, Oral 7 253.540 2318827 Microvescicles (MVs) in human Hepatocellular carcinoma (HCC): Potential for diagnostic and therapeutic applications. Abruzzo EST Oncology 1 Basic 7 202.740 2315888 Dissecting the role of plasmacytoid dendritic cells in the progression of cutaneous melanoma Lombardia EST Oncology 1 Basic 7 296.140 2313497 Early detection and treatment of recurrent, chemotherapyresistant ovarian cancer stem cells by CPE peptide complexed superparamagnetic iron oxide nanoparticles (CPE SPIONs) ISTITUTO TUMORI MILANO EST Oncology 2 7 301.240 2316197 HPV INFECTION AND DISEASE IN IMMUNOSUPRESSED MALES AND FEMALES: PREVALENCE ANDVIRO IMMUNOLOGICAL DETERMINANTS OF ORGAN DAMAGE IRCCS AOU San Martino IST (Genova) EST Immunology 7 166.140 2308270 Interleukin 27 in the control of pediatric acute leukemia cell growth in NOD/SCID/Il2rg / mice with human immune system GASLINI EST Immunology 7 274.840 2312580 The ECM molecule MULTIMEIN2 as a potential therapeutic tool to hamper tumor angiogenesis and tumor growth. C.R.O. AVIANO EST Oncology 1 Basic 7 184.440 2318448 Towards intervertebral disc regeneration: mesenchymal stem/stromal cells with a novel bioactive hydrogel based approach. MAGGIORE EST Musculoskeletal, Oral 7 291.140 2318561 Nerve Growth Factor eye drops as a novel treatment for vision loss in patients with Retinitis Pigmentosa: from preclinical to clinical Phase II trial. CLI COF Brain Disorders and 7 334.740 Pagina 14 di 31
2314989 Innovative molecular platform for tick borne diseases: suspension array and pyrosequencing for the rapid, accurate and cost effective multi pathogen detection in ticks and biological samples Sperimentale delle Venezie Veterinary 7,25 274.700 (5) 2303934 Identification of new genes involved in the pathogenesis of rare congenital hemolytic anemias. MAGGIORE CLI Genes, Genomes and Genetics 7,25 250.300 2318965 Aedes albopictus in northern Italy: molecular markers and mathematical models to predict its potential future spread and the impact of control strategies Sperimentale della Lombardia e dell'emilia Veterinary 7,5 210.700 (5) 2315883 Schizophrenia pathogenetic mechanisms associated to dysbindin dysfunctions in fly and mouse models MEDEA Brain Disorders and 7,5 281.800 2317593 Role of the meniscus in OA pathology and symptoms RIZZOLI Musculoskeletal, Oral 7,5 246.300 2309585 Development of optical methods for preclinical imaging using radiotracers Bioengineering Sciences and Technologies 7,5 371.200 2302354 Role of micrornas 143 and 145 in cardiovascular physiology and disease: from bench to bedside MULTIMEDICA Vascular and Hematology 7,5 371.200 2321713 Integrated program of clinical research to reduce the mortality rate of patients on the waiting list for lung transplantation Piemonte CLI Cardiovascular and Respiratory Sciences 7,5 200.600 2311017 MacroH2A1 in the pathogenesis of metabolic syndromeassociated hepatocellular carcinoma CASA SOLLIEVO SOFFERENZA EST Oncology 1 Basic 7,5 229.000 (4) 2316319 Evaluation of interaction between NK cells and colorectal carcinoma cells for development of NK cell based immunotherapy in patients with refractory disease SAN MATTEO CLI Oncology 2 7,5 402.700 Pagina 15 di 31
2311864 Tailoring the choice of P2Y12 oral receptor blocker by integrating clopidogrel loss of function alleles to phenotype assessment via point of care testing versus standard of care in patients who undergo percutaneous coronary intervention: A randomized mult MAUGERI Cardiovascular and Respiratory Sciences 7,5 336.700 2319582 Involvement of micrornas in triple negative breast cancer: from biology to possible therapeutic applications. ISTITUTO TUMORI MILANO EST Oncology 1 Basic 7,5 218.800 (4) 2304750 Role of estrogen receptors in the pathogenesis and response to treatment of chronic lymphocytic leukemia Istituto Superiore di Sanita' CLI Oncology 1 Basic 7,5 475.700 2303035 The topological organization of anatomical and functional cortical brain networks in patients with the behavioral variant of frontotemporal dementia and primary progressive aphasia CLI Biobehavioral and Behavioral Processes 7,5 322.400 2316264 Deregulation of molecular cross talk between NRF2/KEAP1 and BCL2 pathways in Non Small Cell Lung Cancer (NSCLC) and Small Cell lung Cancer (SCLC): implications for patients treatment. CASA SOLLIEVO SOFFERENZA EST Oncology 2 7,5 210.700 (4) 2312228 Fall prevention and locomotion recovery in post stroke patients: a multimodal training towards a more autonomous daily life MAUGERI CLI Musculoskeletal, Oral 7,5 150.000 2313824 Health literacy and patient empowerment through the development of an e health information system Istituto Superiore di Sanita' CLI Healthcare Delivery 7,5 258.500 2313550 Immunological monitoring of advanced cancer patients undergone active specific immunotherapy with a new anticancer poly peptide vaccine directed against the thymidylate synthase enzyme. Toscana CLI Oncology 2 7,5 150.000 2316475 Alteration in cortical parvalbuminergic System in murine model of Huntington s Disease: Pharmacological effect of Phosphodiesterase type 4 (PDE4) inhibition. SANTA LUCIA Brain Disorders and 7,75 196.500 Pagina 16 di 31
2321799 Parenteral Iron Supplementation, Chemoreflex Response, Quality of Life And Exercise Capacity In Patients With Chronic Heart Failure AUXOLOGICO CLI Cardiovascular and Respiratory Sciences 7,8 230.000 2310057 The role of TRAP1 in the resistance to anti EGFR1 agents in human colorectal carcinoma CROB Oncology 2 8 281.800 2320635 Definition of the epigenetic signature in Multiple Myeloma by high resolution DNA methylation profiling and integrated analysis with genomic imbalance, gene and microrna expression. CROB Oncology 1 Basic 8 371.200 2315984 Climate, global drivers and immunodeficiency: effects on the leishmaniosis transmission patterns in Central Italy and appropriate diagnostic flow charts Sperimentale del Lazio e della Toscana Veterinary 8 216.800 2317212 Development of novel DNA based analytical methods for bacteria detection to improve food safety Sperimentale del Lazio e della Toscana Veterinary 8 338.700 2315933 Search for novel genes involved in heterogeneous Cryopyrin associated periodic syndromes (CAPS) like autoinflammatory disorders GASLINI Genes, Genomes and Genetics 8 281.800 2312766 A multicenter collaborative research network for the identification and study of rare undiagnosed patients: the impact on the rare disease National Health Service network (UnRareNet) OSPEDALE BAMBINO GESU' CLI Healthcare Delivery 8 423.000 2315007 Striatal cholinergic interneurons as a novel target for the treatement of Parkinson's disease Umbria Brain Disorders and 8 150.000 2303748 Planar haptic device and virtual reality tools for hand and finger rehabilitation S.CAMILLO CLI COF Musculoskeletal, Oral 8 150.000 2311055 Molecular mechanisms involved in skeletal muscle repair and muscular dystrophy SAN RAFFAELE PISANA Musculoskeletal, Oral 8 371.200 Pagina 17 di 31
2315822 Deleted in Breast Cancer 1, a new player in the DNA damage response. ISTITUTO TUMORI MILANO AREA Sezione Classificazione Oncology 1 Basic 8 371.200 2313418 Frontal circuit dysfunction as a marker of dementia in parkinsonism NEUROLESI Brain Disorders and 8 371.200 2314003 Undifferentiated thyroid carcinoma: role of the Twist1 transcription factor SDN Oncology 1 Basic 8 281.800 2312686 Nanostructured Coatings Enhancing Material Performances in Joint Arthroplasty RIZZOLI Bioengineering Sciences and Technologies 8 371.200 2318370 New nanotechnology and biomedical approaches to improve postoperative pain treatment reducing risks related to opioids SAN MATTEO CLI EST Surgical Sciences, 8 350.900 (4) Biomedical Imaging, and Bioengineering 2311360 EPIDEMIOLOGICAL SURVEY ON FRESHWATER FISH BORNE PARASITIC ZOONOSES: STUDY OF TIC AND ATIC FACTORS INFLUENCING THE OCCURRENCE OF ZOONOTIC HELMINTHS IN FRESHWATER FISH POPULATIONS FROM NORTHERN ITALY AND IDENTIFICATION OF MAIN RISK FACTORS CONTRIBUTIN Sperimentale del Piemonte, Liguria e Valle d'aosta Veterinary 8 253.400 (5) 2311677 2320784 2320236 High Throughput analysis of cancer cells for therapy evaluation by microfluidic platforms integrating plasmonic nanodevices Development and preclinical assessment of an innovative endovascular device to occlude prosthetic paravalvular leakage IMMUNOLOGICAL IMPACT OF SILIBININ TREATMENT FOR HCV RECURRENCE IN STABLE LIVER TRANSPLANTED PATIENTS Calabria EST Bioengineering Sciences 8 363.100 (4) and Technologies Veneto EST Bioengineering Sciences 8 326.500 (4) and Technologies Puglia CLI COF Immunology 8 150.000 2317596 INVESTIGATION OF THE MOLECULAR BASES OF CARDIOMYOPATHY IN IMMUNOGLOBULIN LIGHT CHAIN (PRIMARY) AMYLOIDOSIS SAN MATTEO Cardiovascular and Respiratory Sciences 8 335.600 Pagina 18 di 31
2319022 Immune gene expression and white matter pathology in first manic patients before and after treatment. A multimodal imaging genetic study Veneto CLI Brain Disorders and 8 305.200 2318960 Unravelling the genetic basis of limb defects through a combined genomic and functional approach Emilia Romagna Genes, Genomes and Genetics 8 267.600 2315604 Electronic health databases as a source of reliable information for effective health policy Puglia CLI Healthcare Delivery 8 150.000 2313991 Toward the development of an in vitro test for ALS: largescale validation of PBMC protein biomarkers Lombardia CLI Brain Disorders and 8 170.100 2309222 Towards development of a next generation sequencing strategy for molecular genetic testing of inherited diseases with blood cell reduction BURLO GAROFALO CLI Vascular and Hematology 8 157.900 2310524 The endocannabinoid system as a therapeutic target to counteract remote degeneration after spinal cord injury. SANTA LUCIA CLI Brain Disorders and 8 185.300 2311171 Attention control in complex environments: mechanisms of spatial orienting in the intact and the damaged human brain SANTA LUCIA CLI Integrative, Functional, and Cognitive Neuroscience 8 212.700 2316606 Optimization of alloreactive natural killer (NK) cell and invariant NKT (inkt) cell mediated anti leukemia effect in children with hematological malignancies given a T cell depleted hematopoietic stem cell transplantation (HSCT) from an HLA disparate rel OSPEDALE BAMBINO GESU' CLI Oncology 2 8 296.000 2313155 Effects of resveratrol on inflammation in type 2 diabetic patients. A double blind randomised controlled trial Piemonte CLI Endocrinology, Metabolism, Nutrition and Reproductive Sciences 8 150.000 2321706 The rehabilitation of attention in patients with mild cognitive impairment and brain subcortical vascular changes using the Attention Process Training II Toscana CLI Brain Disorders and 8 150.000 Pagina 19 di 31
2315136 MSC based therapy for the bone marrow and solid organs transplantations Lombardia CLI Oncology 2 8 150.000 2321788 Hyperpolarized 13C Magnetic Resonance Metabolic Imaging as Sensitive Biomarker in a cardiac translational study of Heart Failure Toscana CLI Cardiovascular and Respiratory Sciences 8 387.400 2316063 EFFICACY OF TELEMEDICINE FOR IMPROVING DEPRESSION OUTCOMES IN PRIMARY CARE FATEBENEFRATELLI CLI Healthcare Delivery 8 352.900 2308551 Role of antiviral treatment on the course of severe liver disease due to chronic HCV infection Sicilia CLI Digestive, Kidney and Urological Systems 8 150.000 2309734 Does calorie restriction ameliorate renal function and cardiometabolic health in obese type 2 diabetic patients? Istituto Superiore di Sanita' CLI Endocrinology, Metabolism, Nutrition and Reproductive Sciences 8 271.700 2316374 Familial breast cancer cases from an isolated population: detection of new risk alleles by exome sequencing and depiction of mutation spectrum in known susceptibility genes. Lombardia CLI Oncology 1 Basic 8,25 212.700 2310981 Congenital Myopathies: genetic screening starting from a new diagnostic algorithm OSPEDALE BAMBINO GESU' CLI EST Musculoskeletal, Oral 8,5 332.600 (4) 2316179 MOLECULAR EPIDEMIOLOGY OF METHICILLIN RESISTANT STAPHYLOCOCCUS AUREUS IN A THIRD LEVEL PAEDIATRIC UNIVERSITY HOSPITAL Toscana CLI Infectious Diseases and Microbiology 8,5 243.200 2315118 Investigation on the prognostic value of biochemical markers in the cerebrospinal fluid for the functional outcome of spinal cord injured patients Emilia Romagna CLI Brain Disorders and 8,5 281.800 2321254 Non inferiority trials for cutting drug expenses in neurology: comparing 2 interferon beta 1b regimes in Multiple Sclerosis Lazio CLI Brain Disorders and 8,5 150.000 Pagina 20 di 31
2316138 INNOVATIVE METHOD FOR THE TREATMENT OF TOTAL LIMBAL STEM CELLS DEFICIENCY (LSCD) THROUGH A TISSUE ENGINEERED HEMICORNEA Veneto CLI Bioengineering Sciences and Technologies 8,5 275.700 2317105 The contribution of ICT to patient safety in surgical process Emilia Romagna CLI Healthcare Delivery 8,5 150.000 2321801 Development and testing of an entirely automated system, based on administrative data, to stratify prognosis of older patients accessing an Emergency Department Toscana CLI Healthcare Delivery 8,5 150.000 2316524 An opportunistic screening strategy to improve the triage of skin cancer by primary care physicians A randomized study ARCISPEDALE CLI Healthcare Delivery 8,5 150.000 2318081 Anti idiotypic Network to Anti transglutaminase Antibodies in the Prevention of Celiac Disease Enteropathy. BURLO GAROFALO CLI Digestive, Kidney and Urological Systems 8,5 150.000 2315762 Progressive Neurodegeneration in Primary Immunodeficiencies (PIDs): characterization, genetic predisposition, pathogenesis and identification of predictive biomarkers for diagnosis and follow up FATEBENEFRATELLI EST Immunology 8,5 244.200 (4) 2303444 TARTEGED TREATMENT OF HAIRY CELL LEUKEMIA Umbria CLI Oncology 2 8,5 210.700 2319335 Empowering the brain. Induction of Hebbian like plasticity in cortico cortical neural networks with transcranial magnetic stimulation (TMS): investigations of functional connectivity in healthy subjects and clinical trials in stroke patients Lazio EST Brain Disorders and 8,5 314.300 (4) 2309640 Anosognosia in preclinical and clinical Alzheimer disease as early marker of illness outcome prediction: impact of precocious clinical diagnosis and rehabilitative intervention SANTA LUCIA CLI Brain Disorders and 8,5 200.600 Pagina 21 di 31
2316776 A machine learning approach to pharmacogenomics. Application to therapy of autoimmune diseases, Myastenia Gravis and Multiple Sclerosis. CARLO BESTA CLI Genes, Genomes and Genetics 8,5 282.800 2318922 Care pathway for dementia: effects on professional practice, patient outcomes, and costs for the NHS. CARLO BESTA CLI Brain Disorders and 8,5 302.100 2315839 Direct Acting Antivirals (DAAs) for HCV infection: a nationwide research project to evaluate virological and clinical outcomes, to design appropriate treatment algorithms, and to assess cost effectiveness of the new combination therapies Istituto Superiore di Sanita' CLI Infectious Diseases and Microbiology 8,5 423.000 2312316 Perioperative Optimization of Care in Obesity: Acronym: POCO Toscana CLI Surgical Sciences, Biomedical Imaging, and Bioengineering 8,5 255.400 2307262 Identification of treatment dependent and treatment independent biological predictors of chemorefractoriness and outcome in a phase III trial of high risk diffuse large B cell lymphoma (DLCL04) Provincia autonoma Bolzano CLI Oncology 2 8,5 387.400 2314047 LKB1/AMPK status and glycolytic phenotype as biomarkers of response of lung cancer to bevacizumab I. O. V. CLI Oncology 2 8,5 150.000 2311890 Identification of mirnas involved in the regulation of ALK expression in neuroblastoma IRCCS AOU San Martino IST (Genova) EST Oncology 1 Basic 8,5 150.000 (4) 2309463 ROLE OF RIBOFLAVIN TRANSPORTERS IN MOTOR NEURON DISEASES: Genetic analysis of the Brown Vialetto Van Laere and Fazio Londe syndromes and development of potential treatment strategies for motor neuron diseases. MAGGIORE Molecular, Cellular, and Developmental Neuroscience 8,5 348.900 2320644 THE RESPONSIVENESS TO CLOPIDOGREL AND STENT THROMBOSIS 3 (RECLOSE 3) TAILORED THERAPY Toscana CLI Cardiovascular and Respiratory Sciences 8,5 423.000 2312769 DESIGNING MOLECULAR CHAPERONS FOR PROTEINS: A NEW STRATEGY FOR DRUG DISCOVERY IN NEURODEGENERATIVE DISEASES Istituto Superiore di Sanita' Molecular, Cellular, and Developmental Neuroscience 8,5 371.200 Pagina 22 di 31
2316745 SPES Service for detection of Pre psychoses: from geneenvironment interactions to phenomenology MEDEA Brain Disorders and 8,5 371.200 2318945 Disentangling endogenous resident adult cardiac stem cell biology and aging for clinical protocols of myocardial regeneration without cell transplantation Calabria Cardiovascular and Respiratory Sciences 8,5 317.400 2317550 Investigating KAP1 mediated epigenetic control of differentiation and function of adaptive immune system Immunology 8,5 371.200 2305717 Perinatal life threatening arrhythmias and Sudden Infant death SAN MATTEO Genes, Genomes and Genetics 8,5 366.100 2308100 Targeting strategies in Numb defective cancers I.E.O. Oncology 1 Basic 8,5 371.200 2316671 Functional and structural changes induced by repetitive transcranial magnetic stimulation on corticostriatal pathway in models of Parkinson s disease and dyskinesia SANTA LUCIA Brain Disorders and 8,5 196.500 2313255 Integration of advanced molecular analyses and magnetic resonance imaging for the identification of biomarkers of disease progression in multiple sclerosis. Istituto Superiore di Sanita' Brain Disorders and 8,5 297.000 2307655 lipidomic investigations in Multiple Sclerosis: research ofmolecular biomarkers Abruzzo Biological Chemistry and Macromolecular Biophysics 8,5 162.000 2312023 MEF promotes stemness in the pathogenesis of gliomas FATEBENEFRATELLI Oncology 1 Basic 8,5 371.200 2313451 Hyperthophic cardiomyopathy: new insights from deep sequencing and psycosocial evaluation. Lombardia CLI COF Cardiovascular and Respiratory Sciences 8,5 210.700 2315581 UNRESECTABLE IN TRANSIT METASTATIC MELANOMA: ELECTROCHEMO THERAPY VERSUS ELECTROIMMUNOTHERAPY. LOCAL AND SYSTEMIC EFFECTS. PASCALE CLI COF Oncology 2 8,5 150.000 Pagina 23 di 31
2318138 Modulation of calcium release activated calcium modulator 1 (ORAI 1) and Stromal interaction molecule 1 (STIM1) activity as a new therapeutical strategy in stroke SAN RAFFAELE PISANA Brain Disorders and 8,5 150.500 2319551 A multicenter epidemiological and clinical study on Deep Brain Stimulation (DBS) for Parkinson s disease: adherence to current recommendations, safety and outcome. MAGGIORE CLI Brain Disorders and 8,75 150.000 2313671 A combination of surveys, spatial analyses and molecular epidemiology to get an insight of pre harvest risks from Shiga toxin producing Escherichia coli. Sperimentale del Piemonte, Liguria e Valle d'aosta Veterinary 9 327.500 (5) 2318002 Novel multiplexing and signal amplification strategies for the development of advanced diagnostic platforms for animal health and food safety control Sperimentale della Lombardia e dell'emilia Veterinary 9 237.100 (5) 2304510 CERVICAL PLETHYSMOGRAPHY: A NEW TOOL FOR NON INVASIVE ASSESSMENT OF CEREBRAL VENOUS RETURN, AND A POSSIBLE SCREENING DEVICE FOR CHRONIC CEREBROSPINAL VENOUS INSUFFICIENCY Emilia Romagna CLI COF Vascular and Hematology 9 150.000 2322039 Porous titanium combined with an osteoinductive hydrogel and cells: an innovative strategy to improve prosthetic implants osteointegration GALEAZZI COF Musculoskeletal, Oral 9 150.000 2319571 Noise and air pollution from road traffic and incidence of coronary and cerebrovascular events in three Italian cohort studies Lazio CLI Population Sciences and Epidemiology 9 267.600 2314264 METHODS FOR NON INVASIVE QUANTITATIVE ASSESSMENT OF FATTY LIVER SDN CLI Digestive, Kidney and Urological Systems 9 176.200 2310570 DECISION SUPPORT SYSTEM TO IMPROVE APPROPRIATENESS OF REPEATED EXECUTION OF LABORATORY EXAMINATIONS Emilia Romagna CLI Healthcare Delivery 9 352.900 Pagina 24 di 31
2315893 Antiepileptic Drugs and pregnancy. Population based pharmaco epidemiological study on prescription patterns, pregnancy outcome and foetal health Istituto Scienze Neurologiche AREA Sezione Classificazione CLI Population Sciences and Epidemiology 9 210.700 2308995 Manufacturing information of orthopedic articular prosthesis. Analysis of specific safety issues for radiotherapy, magnetic resonance, orthopedic surgery and identification of a traceability model. Emilia Romagna CLI Healthcare Delivery 9 150.000 2310116 A randomized controlled trial of diet and physical activity in BRCA mutation carriers ISTITUTO TUMORI MILANO CLI Risk, Prevention and Health Behavior 9 201.600 2307929 BORON NEUTRON CAPTURE THERAPY (BNCT) IN CUTANEOUSRECURRENCES OF BREAST CANCER: THE DIAGNOSTIC AND THERAPEUTICUTILITY OF 18F FBPA PET/CT I. O. V. CLI Oncology 2 9 150.000 2318865 The Lausanne Trilogue Play used as a psychodiagnostic and therapeutic tool in a Neuropsychiatric Unit: an innovative clinical experience working with psychitric children and adolescent Veneto CLI Risk, Prevention and Health Behavior 9 150.000 2317133 Systematic review on the interventions to reduce waiting lists for elective procedures Emilia Romagna CLI Healthcare Delivery 9 150.000 2317873 Supporting an early autism spectrum disorders diagnosis through the support vector machine approach STELLA MARIS CLI Brain Disorders and 9 150.000 2319668 Early Detection in Autism Spectrum Conditions STELLA MARIS CLI Brain Disorders and 9 162.000 2320098 IMPACT OF VITAMIN D SUPPLEMENTATION ON SKELETAL AND NON SKELETAL MANIFESTATIONS IN PATIENTS WITH PRIMARY HYPERPARATHYROIDISM SUBMITTED TO PARATHYROIDECTOMY OR FOLLOWED WITHOUT SURGERY CASA SOLLIEVO SOFFERENZA CLI Healthcare Delivery 9 203.600 2319745 Presbyphagia: analysis of diagnostic criteria and identification of potential innovative treatments MONDINO CLI Healthcare Delivery 9 326.500 Pagina 25 di 31
2312561 IMMUNOSUPPRESSIVE AND REGENERATIVE CAPACITY OF AUTOLOGOUS ADIPOSE DERIVED MESENCHIMAL STEM CELLS FOR THE TREATMENT OF PATIENTS WITH CROHN DISEASE Emilia Romagna CLI Digestive, Kidney and Urological Systems 9 317.400 2318552 PREDICTION AND PREVENTION OF FALLS IN SUBJECTS SUFFERING FROM NEUROLOGICAL DISEASES Lombardia CLI Risk, Prevention and Health Behavior 9 150.000 2319611 Brain Computer Interface driven rehabilitation after stroke: an add on intervention for hand motor recovery SANTA LUCIA CLI Brain Disorders and 9 150.000 2319605 Polypharmacy Reduction of Inappropriate Medication and Adverse Drug Events in Older Patients: a Randomized Controlled Trial PRIMA Provincia autonoma Bolzano CLI Healthcare Delivery 9 150.000 2322017 The implementation of an enhanced recovery program ( fast track) after colorectal resection for colonic cancer Emilia Romagna CLI Surgical Sciences, Biomedical Imaging, and Bioengineering 9 150.000 2321501 Biological bone reconstruction in children skeleton after sarcoma resection. Validation of the technique through CT scan analysis and histological evaluation of the retrieved cases RIZZOLI CLI Surgical Sciences, Biomedical Imaging, and Bioengineering 9 196.500 2318554 Assessment of Stable and Unstable atherosclerotic plaque in coronary disease using Positron Emission Tomography Computed Tomography (PET TC) and Optical Coherence Tomography (OCT).[SUSPECT trial] Lazio CLI Cardiovascular and Respiratory Sciences 9 150.000 2318192 Oral steroids for reducing renal scarring in infants with febrile urinary tract infections at high risk for renal scar development: a randomized controlled trial Veneto CLI Infectious Diseases and Microbiology 9 150.000 2309748 MAPPING THE CORTICOSPINAL TRACT: INVESTIGATION OF FUNCTIONAL PROPERTIES OF THE DIFFERENT CORTICAL AREAS ORIGINATING CST AND THEIR CLINICAL IMPACT ON TUMOR RESECTION AND PATIENT FUNCTIONAL OUTCOME HUMANITAS CLI Integrative, Functional, and Cognitive Neuroscience 9 191.400 Pagina 26 di 31
2316359 Longitudinal clinical neuropsychological study of subjective memory complaints Toscana CLI Brain Disorders and 9,25 150.000 2312497 Adaptation to predictable postural perturbations: physiological basis for an innovative approach to dynamic balance training in Parkinson s disease MAUGERI CLI Brain Disorders and 9,25 169.100 2320550 Evaluation of extrapyramidal involvement in amyotrophic lateral sclerosis (ALS): a prospective cohort survey Piemonte CLI Brain Disorders and 9,5 150.000 2304417 Improved pre surgical evaluation of the human epileptogenic zone with a novel intracranial recording/analysis platform CARLO BESTA COF Brain Disorders and 9,5 150.000 2303193 Individualized treatment of patients with advanced NSCLC: potential application for Circulating Tumor Cells (CTC) molecular and phenotypical profiling I. O. V. CLI Oncology 2 9,5 204.600 2318525 A comprehensive strategy to eradicate prion diseases from the Italian sheep and goat population Sperimentale della Sicilia Veterinary 9,5 390.500 (5) 2310662 FEASIBILITY AND COST EFFECTIVENESS OF A MULTIDISCIPLINARY HOME TELEHEALTH INTERVENTION PROGRAMME TO REDUCE FALLS AMONG ELDERLY DISCHARGED FROM HOSPITAL: A PILOT RANDOMIZED CONTROLLED TRIAL MAUGERI CLI Risk, Prevention and Health Behavior 9,5 157.900 2313040 Use of protective cultures of lactic acid bacteria to control colonizing mastitis pathogens in the mammary gland of dairy small ruminants as an alternative to antibiotics Sperimentale della Sardegna Veterinary 9,5 320.400 (5) 2319503 THE USE OF MRI DERIVED MARKERS TO EARLY PREDICT CONSCIOUSNESS RECOVERY INCOMATOSE PATIENTS Lombardia CLI Brain Disorders and 9,5 156.900 2311299 Optimization of the clinical management of endocrineresponsive early breast cancer patients IRCCS AOU San Martino IST (Genova) CLI Oncology 2 9,5 348.900 Pagina 27 di 31
2318620 Optimizing and integrating the delivery of primary care services for risky drinkers in Region Friuli Venezia Giulia Friuli Venezia Giulia CLI Healthcare Delivery 9,5 150.000 2311282 EFFECTS OF LESIONS OF PARIETAL AND FRONTAL CORTEX ON BOTTOM UP FEATURE DETECTION IN THE HUMAN VISUAL CORTEX: CLINICAL/REHABILITATIVE IMPLICATIONS FOR DISERS OF SPATIAL ATTENTION IN STROKE PATIENTS SANTA LUCIA CLI Brain Disorders and 9,5 189.400 2317320 Soluble biomarkers predicting coronary bypass graft patency MONZINO CLI Surgical Sciences, Biomedical Imaging, and Bioengineering 9,5 301.100 2312910 Validation of molecular signatures in liver lesions as paradigm for discovery of new biomarkers and therapeutic targets PASCALE CLI Oncology 2 9,5 263.500 2317292 Telemedicine Services for UTAP Veneto CLI Healthcare Delivery 9,5 405.700 2314841 Role of 18F FLT PET/CT in patients with suspect lymphoma relapse Emilia Romagna CLI Oncology 2 9,5 150.000 2312659 Effects of proton pump inhibitors on mortality and rehospitalization in older subjects : focus on the insulin like growth factor system and implications for health care system. Emilia Romagna CLI Population Sciences and Epidemiology 9,5 150.000 2316600 Evaluation of a multidisciplinary team case management on clinical outcome in a tertiary traumatology centre. Toscana CLI Healthcare Delivery 9,5 150.000 2314903 Screening of children at risk for language and communication disorders Lazio CLI Biobehavioral and Behavioral Processes 9,5 176.200 2314784 Food irradiation: quality and detection of plant origin food with health benefits Sperimentale della Puglia e della Basilicata Veterinary 9,5 311.300 (5) Pagina 28 di 31
2308141 EXTENDING COMPREHENSIVE CANCER CENTERS EXPERTISE IN PATIENT EDUCATION: THE POWER OF PARTNERSHIP WITH PATIENT REPRESENTATIVES C.R.O. AVIANO CLI Healthcare Delivery 9,6 175.200 2318198 Prognostic marker of cytomegalovirus infection and transmission in pregnancy. Emilia Romagna CLI Infectious Diseases and Microbiology 9,67 150.000 2311041 ACTION OBSERVATION TREATMENT (AOT) IN MILD ALZHEIMER DISEASE: A RANDOMIZED CONTROLLED TRIAL. Emilia Romagna CLI Brain Disorders and 9,75 150.000 2312866 An intervention aimed at improving the cognitive, physical, and psychiatric functioning of patients with Mild Cognitive Impairment: A randomized control trial of physical exercise and cognitive stimulation. Lazio CLI Risk, Prevention and Health Behavior 9,8 280.800 2308483 Development and optimization of a dedicated selfshielded system to perform accelerated partial breast irradiation in prone position after breast conserving surgery. REGINA ELENA CLI COF Oncology 2 10 363.100 2320665 Cancer biomarker detection using micro structured/superhydrophobic surfaces and advanced spectroscopy techniques Calabria COF Bioengineering Sciences and Technologies 10 181.300 2314193 Cost Utility of Conventional Hemodialysis (CHD) versus Short Daily Hemodialysis (SDHD) for patients coming from Automated Peritoneal Dialysis (APD): A randomized controlled trial Puglia CLI COF Healthcare Delivery 10 150.000 2317993 A new automatic device for personalized clinical monitoring of thrombotic and hemorraghic risk assessment in cancer patients C.R.O. AVIANO COF Oncology 2 10 342.200 2315142 Development of brain targeted epigenetic drugs for the treatment of neurodegenerative disorders and brain ischemia S.CAMILLO COF Brain Disorders and 10 150.000 Pagina 29 di 31
2317349 Role of SAMITAL in prevention of chemo radiation (CT/RT) induced oral mucositis in cancer patients. A Phase 2 Randomized Controlled trial in adults and a feasibility study in paediatric patients I. O. V. CLI COF Oncology 2 10 181.300 2319384 Developing innovative methods for detecting emerging food allergens and evaluation of their impact on consumer health: an integrated approach.integrall Sperimentale del Piemonte, Liguria e Valle d'aosta Veterinary 10 344.800 (5) 2317095 Assessing antibiotic resistance in nonpathogenic foodrelated bacteria: the impact on human gut microbiota Sperimentale delle Venezie Veterinary 10,25 344.800 (5) 2310899 Campylobacter, L. monocytogenes and Verocytotoxinproducing E. coli (VTEC) in Italy: a molecular epidemiology approach to identify sources of infection and risk factors for human exposure Sperimentale dell'abruzzo e del Molise Veterinary 10,25 344.800 (5) 2315184 Molecular determination of Salmonella serovars by using microsphere based suspension array Sperimentale delle Venezie Veterinary 10,5 179.200 (5) 2318757 DOSE WARPING METHODS FOR IGRT AND ADAPTIVE RT: DOSE ACCUMULATION BASED ON ORGAN MOTION AND ANATOMICAL VARIATIONS OF THE PATIENTS DURING RADIATION THERAPY TREATMENTS Emilia Romagna COF Oncology 2 10,5 189.400 2314258 ß amyloid control of peripheral and neuronal glucose uptake NEUROMED COF Brain Disorders and 10,5 210.700 2311608 An integrated analytical, in vivo and in vitro approach to characterize polybrominated diphenyl ethers (PBDEs) in italian mussels: a basis for a Toxic Equivalent Factors (TEF) proposal. Sperimentale dell'umbria e delle Marche Veterinary 10,5 239.200 (5) 2310925 FREMS for Acute Inflammatory Bowel Disease: a Phase I/II Clinical trial Lazio CLI COF Digestive, Kidney and Urological Systems 10,75 150.000 Pagina 30 di 31
2316435 Sebum lipidomics: a new tool to correlate skin and systemic lipid metabolism. SAN GALLICANO COF Musculoskeletal, Oral 11 414.000 LEGENDA : NOTA 1 = Il PI del Progetto ha richiesto un finanziamento inferiore a quello minimo previsto dal NOTA 2 = Principal Investigator non è operatore SSN NOTA 3 = Il Progettoè risultato uguale ad altro progetto presentato nello stesso anche se in altra sezione NOTA 4 = Progetto Giovane Ricercatore Estero Finanziato in quanto con punteggio uguale od inferiore a 8,5 score Limite Finanziamento GR NOTA 5 = Progetto Finanziato per riserva Veterinaria/Sicurezza Alimentare Pagina 31 di 31