Cell/Tissue Engineering and Biomaterials Focus Area - Upper-Level Engineering Courses updated March, 2016 EN.510.311 Structure of Materials 3 EN.510.312 Thermodynamics/Materials 3 EN.510.313 Mechanical Properties of Materials 3 EN.510.314 Electronic Properties of Materials 3 EN.510.315 Physical Chemistry of Materials II 3 EN.510.316 Biomaterials I 3 EN.510.403 Materials Characterization 3 EN.510.407 Biomaterials II: Host response and biomaterials applications 3 EN.510.415 The Chemistry of Materials Synthesis 3 EN.510.421 Nanoparticles 3 EN.510.422 Micro and Nano Structured Materials & Devices 3 EN.510.426 Biomolecular Materials I - Soluble Proteins and Amphiphiles 3 EN.510.430 Biomaterials Lab 3 EN.510.435 Mechanical Properties of Biomaterials 3 EN.510.606 Polymer Chemistry & Biology 3 EN.530.410 Biomechanics of the Cell 3 EN.530.426 Biofluid Mechanics 3 EN.530.446 Experimental Methods in Biomechanics 3 EN.530.448 Biosolid Mechanics 3 EN.540.301 Kinetic Processes 3 EN.540.303 Transport Phenomena I 3 EN.540.304 Transport Phenomena II 4 EN.540.306 Chemical & Biomolecular Separations 3 EN.540.400 Project in Design: Pharmacokinetics 3 EN.540.402 Metabolic Systems Biotechnology 3 EN.540.403 Colloids and Nanoparticles 3 EN.540.405 The Design of Biomolecular Systems 3 EN.540.414 Computational Protein Structure Prediction and Design 3 EN.540.416 Current Topics in Protein Structure Prediction 3 EN.540.421 Project in Design: Pharmacodynamics 3 EN.540.422 Introduction to Polymeric Materials 3 EN.540.426 Biomacromolecules at the Nanoscale 3 EN.540.428 Supramolecular Materials and Nanomedicine 3 EN.540.437 Application of Molecular Evolution to Biotechnology 3 EN.540.440 Micro/Nanotechnology: The Science and Eng. of Small Structures 3 EN.540.459 Bioengineering in Regenerative Medicine 3 EN.540.460 Computational and Experimental Design of Biomolecules 3 EN.550.391 Dynamical Systems 4 EN.580.420 Build-a-Genome 4 EN.580.430 Systems Pharmacology and Personalized Medicine 3
EN.580.434 Bioelectricity 3 EN.580.441 Cellular Engineering 3 EN.580.442 Tissue Engineering 3 EN.580.444 Biomedical Applications of Glycoengineering 3 EN.580.448 Biomechanics of the Cell 3 EN.580.452 Cell and Tissue Engineering Lab 3 EN.580.456 Introduction to Rehabilitation Engineering 3 EN.580.457 Rehabilitation Engineering Design Laboratory 3 EN.580.492 Build-a-Genome Mentor 4 EN.580.495 Microfabrication Lab 4 EN.580.643 Advanced Orthopaedic Tissue Engineering 3 EN.670.495 Animation in Nanotechnology & Medicine 3 EN.670.619 Fundamental Physics and Chemistry of Nanomaterials 3 Contact the department advising office for course additions. Cell/Tissue Engineering and Biomaterials Focus Area - Non Upper-Level Engineering Courses (maximum of 3 credits from this list may count in focus area) AS.020.303 Genetics 3 AS.020.337 Stem Cells & the Biology of Aging & Disease 2 AS.020.363 Developmental Biology 3 AS.020.373 Developmental Biology Lab 2 AS.250.391 Proteins and Nucleic Acids 3 EN.580.112 BME Design Group 3 EN.580.211 BME Design Group 3 EN.580.212 BME Design Group 3 EN.580.311 BME Design Group 3 EN.580.312 BME Design Group 3 EN.580.411 BME Design Group 3 EN.580.412 BME Design Group 3 EN.580.413 Design-Team, Team Leader 4 EN.580.414 Design Team/Team Leader 4 EN.580.580 Senior Design Project 3 EN.580.581 Senior Design Project 3 Students may use a maximum of 3 research credits as a non-upper-level engineering course.
Cell and Tissue Engineering (CTE) is an interdisciplinary field that requires students to master multiple subjects ranging from materials science to stem cell engineering. There are standard classes that all CTE students should take, including Biomaterials I and II and both the cell and tissue engineering courses. When selecting your CTE courses beyond these platform classes, the following specialization areas may provide guidance. While designed only to serve as a guide, the areas of specialization represent important subfields within CTE where cutting edge research is taking place. BIOMATERIALS AREA SPECIALIZATION. This area of specialization is for students who plan to build a strong foundation on biomaterials design, synthesis, processing and characterization, as well as understanding in materials-host interactions. Students can select a set of upper electives from the list that covers a variety of topics ranging from biomaterials synthesis and characterization, to biocompatibility of materials, and to various applications of biomaterials. 510.430 Biomaterials Lab (3) 510.606 Polymer Chemistry and Biology (3) 510.617 Advanced Topics in Biomaterials (3) 540.403 Colloids and Nanoparticles (3) 670.619 Fundamentals of Physics and Chemistry in Nanomaterials (3) 510.311 Structure of Materials (3) 510.313 Mechanical Properties of Materials (3) 510.314 Electronic Properties of Materials (3) 510.403 Materials Characterization (3) 510.415 The Chemistry of Materials Synthesis (3) 510.426 Biomolecular Materials (3) 580.495 Microfabrication Laboratory (4) CELL ENGINEERING AREA SPECIALIZATION. This area of specialization is for students who wish to incorporate a strong foundation of cell level and smaller scale (e.g., biochemical and molecular) knowledge into the systems and organism-level knowledge gained from other parts of the BME undergraduate curriculum. To pursue this option, students can select electives that primarily focus on the biochemistry of molecules found within a cell or molecular scale phenomenon (e.g., kinetic processes or transport phenomenon courses). Another cell-based option is to focus on stem cells and complementary coursework (e.g., developmental biology). 530.410 Biomechanics: Cells and Organisms (3) 540.301 Kinetic Processes (4) 540.303 Transport Phenomena I (3) 540.304 Transport Phenomena II (4) 540.426 Biomacromolecules at the Nanoscale (3) 540.460 Computational and Experimental Design of Biomolecules (3) 550.391 Dynamical Systems (4) 580.420 Build-A-Genome (4) 580.448 Biomechanics of Cells and Organisms (3) 580.451/2 Cellular and Tissue Engineering Laboratory (3)
580.492 Build-A-Genome Mentor (4) 020.363 Developmental Biology (3) 020.373 Developmental Biology Laboratory (2) 250.326 Biological Macromolecules: Structure and Function (3) 250.391 Proteins and Nucleic Acids (3) GENERAL TISSUE ENGINEERING AND STEM CELLS. This is a specialization area that focuses on building tissues and includes an emphasis on stem cells as the major building block of tissues. Students can select from a number of courses related to cell and tissue organization and cell biology in addition to the platform biomaterials courses. 580.451/2 Cellular and Tissue Engineering Laboratory (3) 540.459 Bioengineering in Regenerative Medicine (3) 020.363 Developmental Biology (3) 020.373 Developmental Biology Laboratory (2) NANOBIOTECHNOLOGY AREA SPECIALIZATION. This area of specialization is for students who are interested in complementing the fundamental scientific knowledge obtained in the standard BME undergraduate curriculum with a focus on the technological aspects of cell and tissue engineering, with particular emphasis on the nanoscale. Students can select from a variety of upper level courses that cover the design, fabrication, and characterization of particles, surfaces, devices, and delivery systems and how they interact with biological systems. Topics include designing nanomaterials (including those used as growth substrates or those intended as drug delivery vehicles) to interact with cells, using cells for regenerative medicine applications, and manipulating various sub-cellular components and classes of biomacromolecules. 510.415 The Chemistry of Materials Synthesis (3) 510.430 Biomaterials Lab (3) 540.306 Chemical and Biological Separations (3) 540.403 Colloids and Nanoparticles (3) 540.440 Micro/Nanotechnology (3) 540.459 Bioengineering in Regenerative Medicine (3) 540.460 Computational and Experimental Design of Biomolecules (3) 580.420 Build-A-Genome (4)
580.451/2 Cellular and Tissue Engineering Laboratory (3) 580.492 Build-A-Genome Mentor (4) 580.495 Microfabrication Laboratory (4) 670.619 Fundamentals of Physics and Chemistry in Nanomaterials (3) BIOMECHANICS AREA SPECIALIZATION. This area incorporates traditional engineering approaches into understanding tissue structure and function. Students who plan to build a strong foundation on cell and tissue biomechanics and mechanobiology may select from these upper electives. These courses cover topics that range from the mechanical characterization of cells and tissues, cellular responses to mechanical cues, the general properties of materials, and orthopaedic biomechanics. This area complements the Biomaterials specialty. 510.313 Mechanical Properties of Materials (3) 510.403 Materials Characterization (3) 530.410 Biomechanics: Cells and Organisms (3) 580.451/2 Cellular and Tissue Engineering Laboratory (2) 530.446 Experimental Methods in Biomechanics (3) 580.448 Biomechanics of Cells and Organisms (3) 580.643 Advanced Orthopaedic Tissue Engineering (3) 530.445 Introductory Biomechanics (3) 530.448 Biosolid Mechanics (3) 530.495 Microfabrication Laboratory (4)