Ministero della Salute Direzione Generale Ricerca Sanitaria e Biomedica e della Vigilanza sugli Enti BANDO 2011 2012 RICERCA FINALIZZATA GRADUATORIA PROGETTI ORDINARI 02348435 Investigation of the role of extracellular ATP and the P2X7 receptor in the modulation of immunosuppression within tumour microenvironment Emilia Romagna Biomedical Immunology Oncology 5 02351840 Defective Glucose Metabolism in Polycystic Kidney Disease Defines a Novel Therapeutic Strategy: a Pre Clinical Proof of Concept Study SAN RAFFAELE Milano Biomedical Digestive, Kidney and Urological Systems 5 02352006 Gender and geographical specific circulating microrna signatures as biomarkers of atherosclerosis, atherosclerosis progression and vascular events MONZINO Clinical Vascular and Hematology 5,5 02348315 Defining the cis regulatory bases for variability in inflammatory gene expression in humans: a 3 D analysis in the nuclear space I.E.O. Biomedical Genes, Genomes and Genetics 5,5 02350693 To unravel the molecular basis of neurodevelopmental disorders CASA SOLLIEVO SOFFERENZA Biomedical Genes, Genomes and Genetics 5,5 Pagina 1 di 231
02351092 "Detection of pathological prion protein in cerebrospinal fluid by real time quaking induced conversion (QuIC): Evaluation and standardization of a novel disease specific laboratory test for the diagnosis of sporadic Creutzfeldt Jakob disease." Ist.Sci. Neurologiche Bologna Biomedical Brain Disorders and Clinical 6 02348358 Immune, procoagulant and inflammatory responses in severe sepsis and septic shock MAGGIORE Biomedical Immunology 6 02347228 Altered host virus interaction as cause of multiple sclerosis: focus on Epstein Barr virus and antiviral immune response ISS Biomedical Brain Disorders and Clinical 6 02352291 Assessment of the macrophage role in the natural history of myeloproliferative neoplasms SAN RAFFAELE Milano Biomedical Oncology 1 Basic Translational Oncology 6,5 02352852 Dynamics and ultrastructure of stress sensing SAN RAFFAELE Milano Biomedical Cell Biology The new biotechnologies 6,5 02350836 New nano systems for targeted delivery of cytokines to tumors SAN RAFFAELE Milano Biomedical Oncology 2 Translational Clinical Oncology 6,5 02350857 Role of anoctamin 1 in iodide transport and implications for the efficacy of radioiodinebased cancer therapy. Emilia Romagna Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Oncology 6,5 02346976 Identification of critical p53 co regulators and effectors during tumor suppression I.E.O. Biomedical Genes, Genomes and Genetics Oncology 6,5 Pagina 2 di 231
02350617 Determinants of Type 1 Diabetes (T1DM) clinical onset and progression in paediatric immigrant population Piemonte Clinical Endocrinology, Metabolism, Nutrition and Reproductive 6,5 02348466 GENome wide association study to Evaluate genetic risk factors for cerebral sinusvenous thrombosis (GENESIS Study) MAGGIORE Biomedical Genes, Genomes and Genetics 6,75 02349806 Mitochondrial targeting in LRRK2 associated parkinsonism (PARK8) SANTA LUCIA Biomedical Brain Disorders and Clinical 7 02350347 An integrated genomic, transcriptomic and epigenomic approach in multiplex multiple sclerosis families. SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 7 02349985 Production of novel diagnostic and therapeutic antibodies directed against stem cells in colorectal and lung cancer REGINA ELENA Biomedical Oncology 2 Translational Clinical Oncology 7 02351165 Translational genetics of hereditary spinocerebellar degenerations: highthroughput exome sequencing and model organisms for the identification and characterization of novel disease genes CARLO BESTA Biomedical Genes, Genomes and Genetics 7 02351474 Dysregulated RNA metabolism in multiple myeloma SAN RAFFAELE Milano Biomedical Oncology 1 Basic Translational Oncology 7 02352582 N acetylcysteine in the treatment of neuropathic pain NEUROMED Biomedical Brain Disorders and Clinical 7 Pagina 3 di 231
02352331 Systemic Sclerosis and Chronic Graft versus Host Disease: application of novel predictive assays and generation of transgenic animal models Marche Biomedical Immunology 7 02347869 CHANGES IN STRUCTURE AND RECRUITMENT OF MUSCLE SYNERGIES AFTER CORTICAL AND CEREBELLAR LESIONS SANTA LUCIA Biomedical Integrative, Functional, and Cognitive 7,25 02347691 Generation and functional characterization of artificial lymphoid organs with mutipotent stromal progenitors SAN RAFFAELE Milano Biomedical Biology of Development and Aging Oncology 7,25 02350689 Role of regulatory cells and cytokines in the extent of colonic involvement in patients with ulcerative colitis: implications for patient oriented therapy ISS Biomedical Digestive, Kidney and Urological Systems 7,5 02346987 Development of a second generation PCR Based Replicon Typing system to trace and control the antimicrobial resistance spread in Enterobacteriaceae ISS Biomedical Infectious Diseases and Microbiology 7,5 02347907 Enhanced cell therapy: novel strategies to improve transplanted cell survival and engraftment by protection from oxidative stress REGINA ELENA Biomedical Vascular and Hematology 7,5 02347253 Identification and validation of new therapeutic targets in Acute Myeloid Leukaemia I.E.O. Biomedical Oncology 1 Basic Translational Oncology 7,5 Pagina 4 di 231
02348444 Inherited arrhythmias: clinical characterization, genetic geography and experimental studies in the Calabria Region isolate. MAUGERI Biomedical Genes, Genomes and Genetics 7,5 02347470 Regulation of mitotic transitions I.E.O. Biomedical Cell Biology Oncology 7,5 02352638 ADIPOSE DERIVED MESENCHYMAL STEM CELLS AS NEW MINIMALLY INVASIVE REGENERATIVE TREATMENT TO TARGET EARLY OSTEOARTHRITIS: FROM PRE CLINICAL PROCEDURE SELECTION TO CLINICAL APPLICATION IN A RANDOMIZED DOUBLE BLINDED CONTROLLED TRIAL RIZZOLI Clinical Musculoskeletal, Oral and Skin The new biotechnologies 7,5 02350228 Steroid myopathy: pathogenesis and prevention MAUGERI Biomedical Musculoskeletal, Oral and Skin 7,5 02346867 The role of mechanobiology in establishment and progression of intima hyperplasia associated to vein coronary bypass grafts disease MONZINO Biomedical Vascular and Hematology 7,5 02350023 Evaluation of the potential application of bivalve shellfish as bioindicators of pollution for viral pathogens in coastal waters of southern Italy IZS Mezzogiorno Biomedical Veterinary Food safety and animal 7,5 welfare 02350097 Skeletal muscle in Spinal and Bulbar Muscular Atrophy (SBMA): therapeutic target and delivery route for potential treatments Veneto Biomedical Brain Disorders and Clinical 7,5 Pagina 5 di 231
02351229 Stress Activated Protein Kinases MLK3 and p38 as novel therapeutic targets in chemokine driven leukocyte extravasation and non resolving inflammatory processes SAN RAFFAELE Milano Biomedical Immunology 7,5 02348796 ETHYL EICOSAPENTAENOIC ACID ADDED TO INTERFERON ß THERAPY IN RELAPSING REMITTING MULTIPLE SCLEROSIS: A RANDOMIZED PHASE II CLINICAL TRIAL. ISS Biomedical Brain Disorders and Clinical 7,5 02347946 An image analysis platform for automated in situ high content and resolution analysis of tumor heterogeneity: targeting genomic, epigenetic, and functional diversity in tissues by fluorescence microscopy I.E.O. Biomedical Bioengineering and Technologies Oncology 7,75 02347197 Epidrugs and cardiac differentiation: relevance for the 22q11.2 deletion syndrome NEUROMED Biomedical Cardiovascular and Respiratory 8 02349938 From Bench to Bedside: an Integrated Approach to RASopathies ISS Biomedical Genes, Genomes and Genetics 8 02347596 LEKTI, a multifunctional protein involved in skin desquamation and immunity: towards novel therapeutic approaches for rare and common skin diseases IDI Biomedical Musculoskeletal, Oral and Skin 8 02351998 New Molecular Mechanisms of Leukemia Immune Evasion after Allogeneic Hematopoietic Stem Cell Transplantation SAN RAFFAELE Milano Biomedical Oncology 2 Translational Clinical Oncology 8 Pagina 6 di 231
02347120 Cell on chip technology as a novel tool to investigate the crosstalk between cancer and immune cells: role of the transcription factors Interferon Regulatory Factor 1 and 8 (IRF1, IRF8) in melanoma as a model system. ISS Biomedical Oncology 1 Basic Translational The new biotechnologies 8 02350485 NEUROSTEROIDS AS DETERMINANTS OF ANTIEPILEPTIC DRUG REFRACTORINESS IN TEMPORAL LOBE EPILEPSY Emilia Romagna Biomedical Brain Disorders and Clinical 8 02350464 New self powered devices for cochlear stimulation based on piezoelectric nanomaterials Toscana Biomedical Bioengineering and Technologies The new biotechnologies 8 02347337 Dendritic cell based vaccine therapy in indolent non Hodgkin lymphoma patients: a phase I clinical study ISS Biomedical Oncology 2 Translational Clinical Oncology 8 02350993 Investigation of a novel engineered probiotic to treat Clostridium difficile infection SAN RAFFAELE Milano Biomedical Infectious Diseases and Microbiology 8 02349126 Hypoxia, Inflammation and redox status as determinants of malignant progression of cancer stem cells SAN RAFFAELE Pisana Roma Biomedical Oncology 1 Basic Translational Oncology 8 02348970 Structure and biology of the Tat/Env complex and role of anti Tat/Env antibodies in HIV infection: implication for HIV/AIDS preventative vaccine development ISS Biomedical AIDS and Related Research 8 Pagina 7 di 231
02348476 ROLE OF THE NOVEL PRESYNAPTIC PROTEIN PRRT2 IN NEURONAL PHYSIOLOGY AND IN THE PATHOGENESIS OF PAROXYSMAL NEUROLOGICAL DISORDERS SAN RAFFAELE Milano Biomedical Molecular, Cellular, and Developmental 8 02351876 Vitamin D deficiency and obesity after kidney transplantation: multicenter study on gene environment interactions leading to "complex phenotypes" in a human system associated with cardiovascular events and graft rejection. Piemonte Biomedical Digestive, Kidney and Urological Systems 8,5 02348684 Taking a step forwards the preparedness for preventing crises: Improving the molecular detection of emerging pathogens in food. IZS Piemonte, Liguria e Valle d'aosta Biomedical Veterinary Food safety and animal 8,5 welfare 02346754 Tie2 monocyte mediated delivery of IFNalpha into the liver as a novel treatment for colorectal carcinoma (CRC) liver metastases. SAN RAFFAELE Milano Biomedical Oncology 2 Translational Clinical Oncology 8,5 02352379 Sensorimotor Integration. Physiology and Pathophysiology MAUGERI Biomedical Integrative, Functional, and Cognitive 8,5 02349712 Genomic complexity of chronic lymphocytic leukemia (CLL): clinicobiologc implications and pharmacoeconomic evaluation at the beginning of the kinasetargeted treatment era Emilia Romagna Clinical Oncology 2 Translational Clinical Oncology 8,5 02352318 Immunological Mechanisms Involved in The Pathogenesis of Primary Aldosteronism Veneto Clinical Endocrinology, Metabolism, Nutrition and Reproductive 8,5 Pagina 8 di 231
02352308 WHY ME? PROJECT (WM?P). INVESTIGATING WHITE MATTER CONNECTIVITY IN SCHIZOPHRENIA AT IMAGING, CELLULAR, AND TRANSPOSONE LEVELS IN MONOZYGOTIC DISCORDANT TWINS MEDEA Biomedical Brain Disorders and Clinical 8,5 02349693 Vibrio and viruses in shellfish: old and emerging pathogens. Evaluation of exposure levels for the implementation ofprevention strategies. ISS Biomedical Veterinary Food safety and animal 8,5 welfare 02349921 THE ROLE OF THE BRAIN ADIPOCYTE AXIS ACTIVITY IN POTENTIATING ANTIDEPRESSANT EFFICACY ISS Biomedical Biobehavioral and Behavioral Processes 8,5 02346771 Does gut flora influence autoimmune responses in Multiple Sclerosis? The MAIT cell story. SANTA LUCIA Biomedical Immunology 8,5 02347224 CCL2/CCR2 blocking:molecular insights into a potential therapeutic strategy against HIV replication ISS Biomedical AIDS and Related Research 8,5 02347300 Specialized functionally connected membranes as caveolae and exosomes include molecular signature to decode melanoma progression mechanisms exploitable in clinical therapy ISS Biomedical Cell Biology Oncology 8,5 02350455 Electromagnetic guided in situ laser fenestration of endovascular endoprosthesis Toscana Biomedical Surgical, Biomedical Imaging, and Bioengineering 8,5 Pagina 9 di 231
02349269 From protein protein interaction studies new potential therapeutic targets to treat the MLL related acute lymphoblastic leukemias SDN Biomedical Oncology 1 Basic Translational Oncology 8,5 02348164 CARDIOriGEN MicroRNAs inducing cardiac regeneration From discovery towards clinical application Friuli Venezia Giulia Biomedical Cardiovascular and Respiratory 8,5 02351158 Beta adrenoceptor antagonism and biased agonism in the control of pathological neovascularization ISS Biomedical Biological Chemistry and Macromolecular Biophysics 8,5 02352088 Meeting senior members in the search for new associatesof the exclusive hamartromatous gene club Puglia Biomedical Digestive, Kidney and Urological Systems Oncology 8,5 02348346 A long ncrna point of view to FSHD muscular dystrophy pathophysiology and therapeutics. SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 8,5 02349671 Exploring the role of the prokineticin system in experimental autoimmune encephalomyelitis: a preclinical study towards the definition of possible novel targets of therapy for human multiple sclerosis CARLO BESTA Biomedical Immunology 9 02347362 Induced pluripotent stem cells (ipscs) as a tool to develop neuroprotective (autologous) neural stem cell based therapy in multiple sclerosis SAN RAFFAELE Milano Biomedical Brain Disorders and Clinical 9 Pagina 10 di 231
02349717 A new therapeutic window in neurorehabilitation FATEBENEFRATELLI Biomedical Biobehavioral and Behavioral Processes 9 02349251 INFLAMMATORY AND THROMBOCCLUSIVE VASCULOPATHY: THE ROLE OF PROTEINS RELATED TO COMPLEMENT ACTIVATION. C.R.O. AVIANO Biomedical Vascular and Hematology 9 02347490 Uncovering the molecular bases of the association of uromodulin common variants with hypertension and chronic kidney disease for the identification of novel therapeutic strategies SAN RAFFAELE Milano Biomedical Digestive, Kidney and Urological Systems 9 02348839 Identification of therapeutic targets for neurological disorders: analysis of the mechanisms regulating cortical interneuronsdevelopment. SAN RAFFAELE Milano Biomedical Molecular, Cellular, and Developmental 9 02349698 Individual risk in clinically isolated syndromes of conversion to multiple sclerosis and disease progression: an integrated public health clinical genomics approach SAN RAFFAELE Milano Clinical Brain Disorders and Clinical 9 02347608 Clostridium difficile infection in Italy: do we know the true magnitude of the problem? SPALLANZANI Clinical Infectious Diseases and Microbiology 9 02350972 MOLECULAR AND FUNCTIONAL CHARACTERIZATION OF MECHANISMS INVOLVED IN IRON HOMESTASIS AND HEME SYNTHESIS IN ß THALASSEMIC ERYTHROPOIESIS MAGGIORE Biomedical Genes, Genomes and Genetics 9 Pagina 11 di 231
02347675 Radiation biodosimetry in emergency: validation of automated scoring and accuracy of dose prediction AOU San Martino IST Genova Biomedical Oncology 1 Basic Translational Diseases of environmental 9 origin, with reference also to the workplace 02352111 Expression and function of P2 receptors in human psoriatic keratinocytes. Study of their role in psoriasis pathogenesis and research of new potential therapeutic targets Emilia Romagna Biomedical Musculoskeletal, Oral and Skin 9 02350556 Low cost cardio pulmonary monitoring system for avoidable death prevention in the hospital general ward Piemonte Biomedical Cardiovascular and Respiratory 9 02350971 The role of early systematic best palliative care versus on request palliative care consultation during standard oncologic treatment for patients with advanced gastric or pancreatic cancers: a randomized, controlled, multicenter trial IRST Meldola Clinical Healthcare Delivery and Methodologies Oncology 9 02352131 GLP 1 agonists treatment vs endoscopic procedures in obesity and type II diabetes mellitus management: a randomized clinical trial. Piemonte Clinical Endocrinology, Metabolism, Nutrition and Reproductive 9 02347971 Molecular regulation of the redox switch in inflamed skeletal muscle as a novel target to implement muscle regeneration and limit fibrosis in immune mediated myositis SAN RAFFAELE Milano Biomedical Musculoskeletal, Oral and Skin 9 Pagina 12 di 231
02348151 Identification and manipulation of immunosuppressive networks in tumor microenvironment of patients undergoing immunobiological therapies. SAN RAFFAELE Milano Biomedical Immunology Oncology 9 02351216 Cortico cortical functional connectivity and recovery of post stroke spatial attention and awareness disorders SANTA LUCIA Biomedical Integrative, Functional, and Cognitive 9 02349556 Impact of asbestos mediated inflammation in mesothelioma genesis and progression. Implication for early diagnosis, prognosis and therapy HUMANITAS Biomedical Oncology 1 Basic Translational Oncology 9 02351149 Dominant optic atrophy (DOA) and OPAthies in Italy (ITA DOA): minimal prevalence, genetics and phenotypes, and cell models of disease towards a therapy. Ist.Sci. Neurologiche Bologna Biomedical Brain Disorders and Clinical 9 02351889 Eco epidemiology of Mycobacterium bovis infection in Mediterranean area: a multidisciplinary approach. IZS Sicilia Biomedical Veterinary 9 02347935 PRECLINICAL DEVELOPMENT OF THERAPEUTIC, ANTI BETA GLUCAN ANTIBODIES FOR UNIVERSAL PROTECTION AGAINST FUNGAL PATHOGENS ISS Biomedical Infectious Diseases and Microbiology 9 02347945 Caffeine as a potential therapeutic option for Alzheimer's disease ISS Biomedical Brain Disorders and Clinical 9 Pagina 13 di 231
02349393 Human Ewing Sarcoma Family Tumor (ESFT) Revisited From Cancer Stem Cells (CSCs) to the Epigenetic Regulation: crosstalk between ncrna and DNA methylation Lombardia Biomedical Oncology 1 Basic Translational Oncology 9 02350769 Potential role of HDL Cholesterol Efflux Capacity in the evaluation of cardiovascular risk in patients with Familial Hypercholesterolemia (FH) AOU San Martino IST Genova Biomedical Cardiovascular and Respiratory 9 02346892 The low density lipoprotein associated protein prenylcysteine lyase: a novel player in atherosclerosis? MONZINO Biomedical Vascular and Hematology 9 02348166 Constitutive Axl signaling in human melanoma: role in tumor biology and in resistance to BRAFV600E inhibitors IST.TUMORI MILANO Biomedical Oncology 1 Basic Translational Oncology 9 02350853 Identification and validation of novel stem cell markers for the stratification of breast cancer patients. I.E.O. Biomedical Oncology 2 Translational Clinical Oncology 9 02347245 Development of an immunotherapeutic strategy for an effective therapeutic HPV vaccine ISS Biomedical Oncology 2 Translational Clinical Oncology 9 02346811 Towards a functional classification of human melanoma: dissecting the altered intracellular signaling profile by phosphoproteomics approaches IST.TUMORI MILANO Biomedical Oncology 1 Basic Translational Oncology 9 Pagina 14 di 231
02351358 Dietary advanced glycation end products and cardiovascular risk: animal and human studies ISS Biomedical Cardiovascular and Respiratory 9,25 02348236 CARPEDIEM Comorbidity And Risk Profiles Evaluation in Diabetes and heart Morbidities Toscana Clinical Healthcare Delivery and Methodologies 9,25 02347084 Inflammation and oxidative stress in preeclampsia: role of the maternal endothelium and of the placenta, potential role in early markers development Lombardia Biomedical Endocrinology, Metabolism, Nutrition and Reproductive The new biotechnologies 9,5 02349663 Analysis of the possible pathogenic roles of the inflammosome and the microbiota in Alzheimer's disease DON GNOCCHI Biomedical Brain Disorders and Clinical 9,5 02349068 Development of in vitro insulin producing biohybrid organ for the cure of type 1 diabetes Umbria Biomedical Endocrinology, Metabolism, Nutrition and Reproductive 9,5 02349321 Involvement of ADAR1 and ADAR2 RNAediting activity on myeloid leukemia and myeloid cell differentiation: novel future therapeutic implications. OSPEDALE BAMBINO GESU' Biomedical Oncology 1 Basic Translational Oncology 9,5 02349920 Dissecting the role played by mechanotransduction on Cardiac Stem Cell and cardiomyocyte dysfunction. Friuli Venezia Giulia Biomedical Cardiovascular and Respiratory 9,5 Pagina 15 di 231
02348098 Phenotypic, functional and genomic characterization of bone fragility in children and adolescents and their relatives: exploring the susceptibility to fractures in youth for its prevention in adulthood SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics 9,5 02349653 Circulating endothelial progenitor cells as potential predictive and prognostic markers in metastatic colorectal cancer patients Toscana Biomedical Oncology 2 Translational Clinical Oncology 9,5 02348212 Developmental and genetic bases of Opitz G/BBB Syndrome towards better diagnosis and management of syndromic forms of intellectual disability BURLO GAROFALO Clinical Genes, Genomes and Genetics 9,5 02348034 A Nationwide Clinical Study on the Role of Functional HLA DPB1 Matching in Unrelated Hematopoietic Stem Cell Transplantation SAN RAFFAELE Milano Clinical Oncology 2 Translational Clinical Oncology 9,5 02350832 Immune therapy with T regulatory type 1 (Tr1) cells in patients with type 1 diabetes undergoing islet transplantation SAN RAFFAELE Milano Biomedical Immunology 9,5 02347806 The epigenetic basis of glioblastoma multiforme invasiveness and recurrence I.E.O. Biomedical Oncology 1 Basic Translational Oncology 9,5 02347187 Structural genomics/proteomics and solution characterization of proteins of biomedical interest: development of a comprehensive facility, application to therapeutic monoclonal antibodies, and to the fibrin(ogen) integrins cell matrix interactions model sy AOU San Martino IST Genova Biomedical Biological Chemistry and Macromolecular Biophysics Oncology 9,5 Pagina 16 di 231
02347757 Risk assessment of occupational and environmental exposure to benzene and other chemicals at low doses: from molecular mechanisms to biological monitoring Campania Biomedical Risk, Prevention and Health Behavior Diseases of environmental origin, with reference also to the workplace 9,5 02351867 Ghrelin as a new cardiometabolic risk biomarker: from population studies to tissue and cell biology in skeletal muscle and heart. Friuli Venezia Giulia Biomedical Endocrinology, Metabolism, Nutrition and Reproductive 9,5 02350276 Novel multi analyte point of care testing device for rapid diagnosis and management of sepsis and severe infection. Toscana Biomedical Interdisciplinary Molecular and Training 9,5 02352512 MicroRNA Signatures: Novel Biomarkers for early detection of Colorectal Cancer CASA SOLLIEVO SOFFERENZA Biomedical Oncology 2 Translational Clinical Oncology 9,5 02346966 Epigenetic signatures in human glioblastoma cells: implications for tumor biology and treatment AOU San Martino IST Genova Biomedical Oncology 1 Basic Translational Oncology 9,5 02348457 Regulatory mechanisms and therapeutic targeting of melanoma initiating cells Toscana Biomedical Oncology 1 Basic Translational Oncology 9,5 02351139 Phase IV clinical trial of anti viral treatment for Hepatitis C infection in compensated cirrhosis Sicilia Clinical Digestive, Kidney and Urological Systems 9,5 02348309 EXtending Computational Analysis of functional Images to define the total asset of Bone marrow and hematopoietic function in blood disordes (EXCALIBUR) AOU San Martino IST Genova Biomedical Bioengineering and Technologies Oncology 9,5 Pagina 17 di 231
02348446 Long term mechanisms of diabetes prevention and remission after bariatric surgery: study of glucose metabolism, insulin secretion and cardiovascular risk 7 years after Roux en Y Gastric bypass. Toscana Clinical Endocrinology, Metabolism, Nutrition and Reproductive 9,5 02352881 Development Of A Novel Adoptive Cell Transfer Approach (ACT) For Cancer Immunotherapy Based On The Use Of Autologous IFN DC For The Induction Of Anti Tumor Response And Implemented By Strategies Aimed At Extending The Replicative Lifespan Of The Anti Tumo ISS Biomedical Oncology 2 Translational Clinical Oncology 9,75 02352711 Search for new genetic biomarkers for early diagnosis and prevention of Familial Thoracic Aortic Aneurysms and Dissections Emilia Romagna Clinical Genes, Genomes and Genetics 9,75 02347071 Exploiting Immunoglobulin Stereotypy as a marker of prognosis and a target for therapy in Chronic Lymphocytic Leukemia SAN RAFFAELE Milano Biomedical Oncology 1 Basic Translational Oncology 9,75 02347777 Molecular portrait of heterogeneous lesions throughout the course of bovine tuberculosis Sardegna Biomedical Infectious Diseases and Microbiology 10 02347243 Genomic architecture and clonal evolution of myelodysplastic syndromes and myeloproliferative neoplasms SAN MATTEO Biomedical Oncology 1 Basic Translational Oncology 10 02349958 Engineering Commensal Bacteria for the Delivery of Therapeutic Proteins SAN RAFFAELE Milano Biomedical Bioengineering and Technologies 10 Pagina 18 di 231
02350280 Genetic dissection of cystic fibrosis host susceptibility to Pseudomonas aeruginosa infections using a highly genetically diverse mouse resource population, the Collaborative Cross mice SAN RAFFAELE Milano Biomedical Infectious Diseases and Microbiology 10 02347758 Reverse transcriptase inhibitors in an innovative anticancer therapy ISS Biomedical Oncology 1 Basic Translational Oncology 10 02350980 Disruption of white matter integrity in bipolar disorder: changes of diffusion tensor imaging measures as markers of the biological underpinnings of the progressive deterioration of cognition and of the cognitive control of emotions. SAN RAFFAELE Milano Clinical Brain Disorders and Clinical 10 02349918 Searching for early and predictive markers of individual risk for head and neck cancer Toscana Biomedical Oncology 1 Basic Translational Oncology 10 02347970 Optimization of plasma progranulin dosage for predicting null progranulin mutations in neurodegenerative diseases: A pilot Multicentre Italian Study for harmonization of procedures to be translated into clinical practice. FATEBENEFRATELLI Biomedical Brain Disorders and Clinical 10 02350246 Improving social dysfunction through oxytocin administration in non human infants exposed to maternal neglect early during postnatal life ISS Biomedical Biobehavioral and Behavioral Processes 10 Pagina 19 di 231
02351875 IMPACT OF EXPOSURE TO ESTROGEN LIKE ENDOCRINE DISRUPTING CHEMICALS(EEDC) ON PUBERTAL DEVELOPMENT AND ESTABLISHMENT OF REFERENCERANGES FOR EXPOSITION IN CHILDHOOD. OSPEDALE BAMBINO GESU' Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Diseases of environmental origin, with reference also to the workplace 10 02349297 Genetic factors influencing early plasma ribavirin cut off values in HCV therapy to reduce anemia toxicity and improve outcome. Piemonte Biomedical Infectious Diseases and Microbiology 10 02347141 Effect of Ag nanoparticles in controlling Salmonella and Campylobacter in laying hens and clinical and food safety insights IZS Venezie Biomedical Veterinary Food safety and animal 10 welfare 02348959 From the measure of guidelines adherence in oncology to the assessment of health system performance Lombardia Clinical Healthcare Delivery and Methodologies Oncology 10 02348951 Innate immune response as a key factor aimed to optimize HCV patients therapy management SPALLANZANI Biomedical Immunology 10 02350484 Tumor Infiltrating Lymphocytes (TIL) and melanoma: prognostic markers and new terapeutic targets IDI Biomedical Oncology 1 Basic Translational Oncology 10 02346880 Targeted next generation sequencing as tool for molecular diagnosis of rare anemias Campania Biomedical Genes, Genomes and Genetics The new biotechnologies 10 Pagina 20 di 231
02348801 THE ROLE OF SOD1 IN THE NUCLEUS: NEW INSIGHTS INTO THE PATHOGENESIS OF AMYOTROPHIC LATERAL SCLEROSIS (ALS) MONDINO Biomedical Molecular, Cellular, and Developmental 10 02351616 Combining Unconventional T cells with Vaccination in Renal Cell Carcinoma Immunotherapy Puglia Biomedical Oncology 2 Translational Clinical Oncology 10 02352155 modulation of HCN channels by GPR35 in chronic pain Toscana Biomedical Brain Disorders and Clinical 10 02352126 DEVELOPMENT OF NOVEL ANTIBODY ENGINEERED GOLD NANOPARTICLES AS TARGETED DRUG DELIVERY FOR THE TREATMENT OF CHRONIC LUNG ALLOGRAFT DYSFUNCTION Veneto Biomedical Bioengineering and Technologies The new biotechnologies 10 02347986 A NEW STRATEGY FOR THE CONTROL OF RHEUMATOID ARTHRITIS: DUAL ROLE OF THE ATYPICAL CHEMOTACTIC RECEPTOR CCRL2 AS A BIOMARKER AND THERAPEUTIC TARGET HUMANITAS Biomedical Immunology 10 02348348 From lifestyle to mitochondrial benefits: study on a combined therapeutic approach to Huntington's disease ISS Biomedical Brain Disorders and Clinical 10 02348364 New biomarkers for early SIRS/sepsis diagnosis in pediatric and adult patiens. Friuli Venezia Giulia Clinical Infectious Diseases and Microbiology 10 Pagina 21 di 231
02346886 Novel formula milks and neonatal gut microbiota: a dynamic interplay approached by systems biology OSPEDALE BAMBINO GESU' Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Food safety and animal welfare 10 02348953 A Twist code of p53 inactivation in sarcomas: clinicopathological and therapeutic implications C.R.O. AVIANO Clinical Oncology 1 Basic Translational Oncology 10 02351116 NEW ALLOCATION CRITERIA FOR LIVER TRANSPLANTATION IN PATIENTS WITH AND WITHOUT HEPATOCELLULAR CARCINOMA BASED ON TRANSPLANT BENEFIT PRINCIPLES: A MULTICENTER, PROSPECTIVE STUDY. Emilia Romagna Clinical Healthcare Delivery and Methodologies Oncology 10 02348194 Innovative diagnostic approach for hereditary cardiomyopathies MULTIMEDICA Clinical Genes, Genomes and Genetics 10 02352753 MOLECULAR CHARACTERIZATION OF COXIELLA BURNETII FROM DOMESTIC RUMINANTS AND WILDLIFE SPECIES BY MLVA AND NGS TECHNIQUES IZS Mezzogiorno Biomedical Infectious Diseases and Microbiology The new biotechnologies 10 02347276 Investigating the molecular mechanisms leading to genome instability in tumours: analysis of role of the replicationstress response and its potential for early diagnosis and target therapy of cancer ISS Biomedical Oncology 1 Basic Translational Oncology 10 02350889 Prospective Characterization of Circulating Tumor Cells in Patients with Hormone Receptor Positive Metastatic Breast Cancer I.E.O. Clinical Oncology 2 Translational Clinical Oncology 10 Pagina 22 di 231
02350578 IDENTIFICATION OF EPILEPTOGENIC NETWORKS IN SURGICAL EPILEPSIES BY A NON INVASIVE MULTIMODAL APPROACH CARLO BESTA Clinical Brain Disorders and Clinical 10 02349798 Epithelial ovarian cancer: affecting tumor growth by targeting aberrant metabolism. IST.TUMORI MILANO Biomedical Oncology 2 Translational Clinical Oncology 10 02346750 The extracellular matrix protein EMILIN1 as a novel structural and functional determinant of lymphangiogenesis and lymphedema C.R.O. AVIANO Biomedical Vascular and Hematology Oncology 10 02347603 Nationwide study on trends in hospital admissions for major cardiovascular events and procedures among people with and without diabetes in Italy, 2001 2010 Piemonte Clinical Healthcare Delivery and Methodologies 10 02352383 Effects of Tumor associated Fibroblast and hypoxia on the availability of efficient NK cells within the tumor core: characterization of molecular targets for therapy in melanoma and colon cancer. AOU San Martino IST Genova Biomedical Immunology Oncology 10 02347260 In vivo toxi omic signatures for brain and thyroid function: combined exposure to mixtures of endocrine disruptingchemicals and iodine deficiency in animal models and translation to epidemiological/clinical studies ISS Biomedical Endocrinology, Metabolism, Nutrition and Reproductive Diseases of environmental origin, with reference also to the workplace 10 02347402 Non invasive assessment of liver steatosis and fibrosis in pediatric patients SAN MATTEO Clinical Digestive, Kidney and Urological Systems 10 Pagina 23 di 231
02350598 MicroRNA Signature of Vascular Complications in Type 1 Diabetes Piemonte Biomedical Cardiovascular and Respiratory 10 02351315 HPV positive oropharyngeal cancer: characterization of immunological and viral profiles, and their role in the response to treatment SAN MATTEO Clinical Oncology 2 Translational Clinical Oncology 10 02347283 Breast cancer with low risk of local recurrence: 3D Conformal Accelerated and Hypofractionated Partial Breast Irradiation vs. standard whole breast radiotherapy after conservative surgery Emilia Romagna Clinical Oncology 2 Translational Clinical Oncology 10 02351432 The complement and coagulation systems as therapeutic targets in subarachnoid hemorrhage: studies in patients and in experimental models. MAGGIORE Biomedical Brain Disorders and Clinical 10 02347262 RESPONSE ORIENTED MAINTENANCE IMMUNOTHERAPY IN PATIENTS WITH FOLLICULAR LYMPHOMA. Emilia Romagna Clinical Oncology 2 Translational Clinical Oncology 10 02347359 Comparative analysis of genomic and epigenomic alterations induced by leukemogenic AML1 fusion proteins I.E.O. Biomedical Oncology 1 Basic Translational Oncology 10 02347522 Genetic markers in elderly to estimate the risk for vascular diseases by using the peripheral arterial disease model. Sicilia Biomedical Genes, Genomes and Genetics 10,25 Pagina 24 di 231
02347553 A phase II, randomised, placebo controlled trial of neuroprotection with Raltegravir in Secondary Progressive Multiple Sclerosis ISS Biomedical Brain Disorders and Clinical 10,25 02350801 Implementation of Chronic Care Model, using Tele care and Home care, in patients with multiple comorbidities: evaluation of the cost effectiveness and quality of life Toscana Clinical Healthcare Delivery and Methodologies 10,25 02347532 A multi site international RCT comparing regional and general anesthesia in infants for effects on neurodevelopmental outcome at five year of age: The GAS Trial. GASLINI Clinical Brain Disorders and Clinical 10,5 02350214 Muscle imaging in neuromuscular disorders: conventional, high and ultrahigh field imaging studies for coming into a focus STELLA MARIS Biomedical Bioengineering and Technologies The new biotechnologies 10,5 02351947 The molecular basis of cognitive impairment in Williams Beuren Syndrome: a cell reprogramming based approach CASA SOLLIEVO SOFFERENZA Biomedical Genes, Genomes and Genetics 10,5 02347422 Naturally occurring and re programed cancer stem cells in ovarian carcinoma: functional role and clinical implications. I.E.O. Biomedical Oncology 1 Basic Translational Oncology 10,5 02352440 Autonomic cardiovascular evaluation in low respiratory tract infections MAGGIORE Biomedical Cardiovascular and Respiratory 10,5 02352328 Assessing colorectal cancer risk: are DNA viruses and genetic damage in circulating cells valuable biomarkers? Emilia Romagna Biomedical Oncology 1 Basic Translational Oncology 10,5 Pagina 25 di 231
02347127 Genomic approach for motor neuron diseases SAN RAFFAELE Milano Clinical Brain Disorders and Clinical 10,5 02350439 TRAIL producing UC MSCs as cytotherapy to defeat multiple myeloma: a preclinical study. ONCOLOGICO DI BARI Biomedical Oncology 2 Translational Clinical Oncology 10,5 02350623 Paratuberculosis in sheep and goats herds in Calabria and human exposure to Mycobacterium avium subspecies paratuberculosis (MAP) trough dairy products IZS Mezzogiorno Biomedical Veterinary Food safety and animal 10,5 welfare 02347060 Surveillance of the circulation of rotaviruses in the infantile population of Sicily following the introduction of rotavirus vaccination Sicilia Biomedical Infectious Diseases and Microbiology 10,5 02350640 Investigation on the sensitivity of dorsal raphe serotonergic neurons to hypercapnic stimuli in a transgenic mouse model of Sudden Infant Death Syndrome (SIDS) characterized by selective alteration of serotonergic neuron autoinhibition. Toscana Biomedical Brain Disorders and Clinical 10,5 02352520 Project Title: Endoscopic Screening and oncologic appropriate removal of Early colorectal lesions. ENDOSCREEN Piemonte Biomedical Surgical, Biomedical Imaging, and Bioengineering The new biotechnologies 10,5 02348282 Studying the tumor microenvironment to find new therapeutic targets and strategies in Hodgkin lymphoma:the role of Mesenchymal stem cells C.R.O. AVIANO Biomedical Oncology 1 Basic Translational Oncology 10,5 Pagina 26 di 231
02350613 High throughput mutation profiling of Sézary Syndrome: implications for pathogenesis, classification, and potential therapeutic developments. IDI Biomedical Oncology 1 Basic Translational Oncology 10,5 02352036 METABOHEARTFAIL GRAPE mirnas IN REVERSING REMODELING THROUGH MODULATION OF CARDIAC AQUAPORIN 7 AND GLYCEROL UPTAKE IN A SWINE MODEL OF NON ISCHEMIC CHRONIC HEART FAILURE Toscana Biomedical Cardiovascular and Respiratory 10,5 02349080 Brain Mechanisms of Chronic Subjective Dizziness SANTA LUCIA Biomedical Integrative, Functional, and Cognitive 10,5 02346764 TRIMming away HIV 1. infection Role of TRIM proteins in establishement and maintenance of HIV 1 latency SAN RAFFAELE Milano Biomedical AIDS and Related Research 10,5 02351656 GISSI Outliers The CAPIRE (Coronary Atherosclerosis in outlier subjects: Protective and Individual Risk factor Evaluation) study The Life Style sub study MAUGERI Biomedical Risk, Prevention and Health Behavior 10,5 02346871 Exploiting neural stem cell targeted mouse models for improving the understanding of the pathogenetic mechanisms underlying Tuberous Sclerosis Complex and developing novel therapeutic approaches. SAN RAFFAELE Milano Biomedical Brain Disorders and Clinical 10,5 02347571 Cell senescence and age dependent decrease in heart function: role of HMGB1 protein IDI Biomedical Biology of Development and Aging 10,5 Pagina 27 di 231
02352686 Understanding Pancreatic Acinar Cell Carcinoma for better understanding Pancreatic Ductal Carcinoma SAN RAFFAELE Milano Biomedical Oncology 1 Basic Translational Oncology 10,5 02346990 Development of a service interface method ( WebService) beetween family care physicians operating in a primary care setting and nephrologists, for the prevention, diagnosis and treatment of kidney damage in patients with type II diabetes mellitus. Toscana Clinical Digestive, Kidney and Urological Systems 10,5 02351728 Containment of a region wide outbreak of Carbapenem resistant Klebsiella pneumoniae in seven lombardian hospital: molecular characterization, epidemiology and outcome. Lombardia Clinical Infectious Diseases and Microbiology 10,5 02349240 Dynamics of epigenetic landscape during phase specific colorectal cancer reprogramming of stem cells and tissues in a murine stress related carcinogenesis model and human tumor biopsies. CASA SOLLIEVO SOFFERENZA Biomedical Oncology 1 Basic Translational Oncology 10,5 02349381 MicroRNAs regulated by mutated p53 oncoproteins in colon cancer REGINA ELENA Biomedical Oncology 1 Basic Translational Oncology 10,5 02347753 Genetic manipulation of embryonic stem cells and induced pluripotent stem cells (ES and ips) for endorsing cardiac fate toward beating cardiomyocytes: novel strategies for cardiac regeneration in myocardial infarction. NEUROMED Biomedical Cardiovascular and Respiratory 10,5 Pagina 28 di 231
02347686 Food safety of bivalve molluscs: Development and application of molecular tools for identification, quantification and evaluation of antibiotic resistance and virulence potential of food associated enteric and autochthonous bacterial pathogens IZS Umbria e delle Marche Biomedical Veterinary Food safety and animal 10,5 welfare 02350566 MicroRNA regulation in the pathogenesis of MD and in the mechanism of action of antidepressant drugs FATEBENEFRATELLI Biomedical Biobehavioral and Behavioral Processes 10,5 02347244 Dissecting the genetic etiology of epileptic encephalopathies by high throughput sequencing GASLINI Biomedical Brain Disorders and Clinical 10,5 02350571 Heterotypic interactions in thromboinflammatory processes associated with the thrombotic vascular occlusion in sepsis:the role of vitamin K dependent protein C SAN RAFFAELE Milano Biomedical Immunology 10,5 02347340 Pre clinical evaluation of safety and efficacy of intra arterial infusion of mesenchymal stems cells in experimental models ofneurodegenerative parkinsonisms and analysis of potential therapeutic mechanisms: en route for a clinical trial MONDINO Biomedical Brain Disorders and Clinical 10,5 02346822 One or more beta amyloids? Links between amyloid composition and phenotypic heterogeneity in Alzheimer's disease: implications for diagnosis and therapy CARLO BESTA Biomedical Brain Disorders and Clinical 10,5 Pagina 29 di 231
02348713 Genetic variability of Mycobacterium tuberculosis and its implications for transmission dynamics, pathogenesis and immune response SPALLANZANI Clinical Infectious Diseases and Microbiology 10,5 02347356 PHARMACOGENOMICS OF HYPERTENSION: A NEW APPROACH FOR A PERSONALIZED MEDICINE SAN RAFFAELE Milano Clinical Digestive, Kidney and Urological Systems 10,5 02348075 Regulation of SMN2 splicing: implications for novel therapeutic approaches to Spinal Muscular Atrophy SANTA LUCIA Biomedical Molecular, Cellular, and Developmental 10,5 02347365 From breast to brain: study of the molecular mechanisms mediating the development of brain metastasis I.E.O. Biomedical Oncology 1 Basic Translational Oncology 10,5 02352809 Role of mast cells in the pathogenesis of diabetic heart disease. SAN RAFFAELE Milano Biomedical Cardiovascular and Respiratory 10,5 02346983 Investigation on the role of iron and mitochondria in neurodegenerative disorders through the development of new human neuronal cellular systems CARLO BESTA Biomedical Brain Disorders and Clinical 10,5 02346800 A new predictive assay to assess the efficacy of combinatorial treatments against stem cells enriched cultures from metastatic melanoma patients PASCALE Biomedical Oncology 1 Basic Translational Oncology 10,5 02349138 Rethinking neuroinflammation in sporadic AD: exploring novel pathways to boost endogenous neuroprotective mechanisms ISS Biomedical Brain Disorders and Clinical 10,5 Pagina 30 di 231
02352191 Structural imaging in systemic amyloidosis: an inescapable step toward the optimization and validation of more effective therapeutic approaches SAN MATTEO Biomedical Biological Chemistry and Macromolecular Biophysics 10,5 02349156 DEVELOPMENT OF AN EXOSOME BASED IN VIVO TEST TO DETECT PRIONS IN BLOOD IZS Piemonte, Liguria e Valle d'aosta Biomedical Veterinary Food safety and animal 10,5 welfare 02350708 Development of miniaturized assays for the timely diagnosis of rare diseases Piemonte Biomedical Musculoskeletal, Oral and Skin The new biotechnologies 10,75 02349089 Rescue of Transforming Growth Factorbeta 1 signaling as a new strategy for neuroprotection in Alzheimer's disease: role of antidepressant drugs OASI MARIA S.S. Biomedical Brain Disorders and Clinical 10,75 02347827 Unravelling the genetic basis of variable clinical expression in NF1: use of an integrated next generation sequencing platform to identify novel disease causing and modifier genes. CASA SOLLIEVO SOFFERENZA Biomedical Genes, Genomes and Genetics Oncology 10,75 02349204 MITOCHONDRIA AND AUTOPHAGY IN DEGENERATIVE SYNAPSES SANTA LUCIA Biomedical Molecular, Cellular, and Developmental 10,75 02346959 Evaluation of the efficacy of Rapamycin and a DPP 4 inhibitor (Vildagliptin) in improving beta cell function in type 1 diabetes of long duration, a perspective randomized study SAN RAFFAELE Milano Clinical Endocrinology, Metabolism, Nutrition and Reproductive 11 Pagina 31 di 231
02352442 Long term exposure to ambient air pollution and pregnancy outcomes in women of three large Italian longitudinal studies Lazio Clinical Population and Epidemiology Diseases of environmental origin, with reference also to the workplace 11 02351880 Evaluation of anti NA antibodies as possible correlates of protection from influenza disease: development of serological assays designed to detect a truly functional antibody response to influenza vaccination, with specific regard to the anti NA ISS Biomedical Immunology 11 02347399 Senescence Associated micrornas (SAmiRs) in cellular senescence and organismal aging SDN Biomedical Biology of Development and Aging 11 02348370 Postural sway and facial mimicry as behavioral markers of covert motor symptoms in Parkinson's disease in a new differential early diagnostic protocol. SANTA LUCIA Biomedical Biobehavioral and Behavioral Processes 11 02349811 The use of top soils improvers from municipal wastewater treatment plants, on pasture: risk assessment of the associated microbial and organic chemical contamination on grazing food producing animals, and on food safety and food security (SOIL SAFE) ISS Biomedical Veterinary Food safety and animal 11 welfare 02351113 Fighting impaired blood flow and supporting skeletal muscle regeneration in diabetes and peripheral artery disease (PAD): an approach based on unacylated ghrelin (UAG) administration Piemonte Biomedical Vascular and Hematology 11 Pagina 32 di 231
02350906 'Septosomes': System Biology and Pathogenetic Role of Exosomes in Sepsisassociated Immune paralysis and Organ Failures Piemonte Biomedical Immunology 11 02350875 Use of Limbal Adult Stem Cells for Osteo and Condrocyte Differentiation and Application in Bone and in Cartilage Regeneration and Tissue Engineering (ABADIR PROJECT) Sicilia Biomedical Endocrinology, Metabolism, Nutrition and Reproductive The new biotechnologies 11 02351077 Dissecting the pathogenesis and possible reversibility of cachexia in end stage chronic heart failure Sicilia Biomedical Musculoskeletal, Oral and Skin 11 02346917 Transcriptomic profiling in circulating mesenchymal stem cells of patients with degenerative diseases. Veneto Biomedical Genes, Genomes and Genetics 11 02348826 Fertility preservation in gonadotoxic treatments Emilia Romagna Clinical Oncology 2 Translational Clinical Oncology 11 02350733 Co transcriptional and post transcriptional regulation of gene expression by EWS and EWS FLI1 in the pathogenesis of Ewing's Sarcoma SANTA LUCIA Biomedical Oncology 1 Basic Translational Oncology 11 02346984 Identification of new therapeutical targets of cancer stem cells: study of the mechanistics of mitotic spindle alignment to cortical polarity in mammary stem cell asymmetric divisions I.E.O. Biomedical Biological Chemistry and Macromolecular Biophysics Oncology 11 Pagina 33 di 231
02350341 Early treatment of exercise induced pulmonary hypertension in systemic sclerosis Toscana Clinical Immunology 11 02346986 TRAIL receptor embedding in membrane rafts could predict cancer cell susceptibility to TRAIL based molecularly targeted therapy ISS Clinical Oncology 2 Translational Clinical Oncology 11 02349088 A translational approach to hereditary neuropathies AOU San Martino IST Genova Biomedical Molecular, Cellular, and Developmental 11 02347873 Cord blood expanded endothelial progenitors in patients with no option critical limb ischemia. Lazio Biomedical Vascular and Hematology 11 02350673 Screening for Autoimmune Polyglandular Syndrome Type 2 in patients with autoimmune thyroiditis: definition of methodology and cost benefit analysis. Toscana Clinical Endocrinology, Metabolism, Nutrition and Reproductive 11 02350488 Imaging the fate of stem cells in vivo by near infrared technology: a translational study for longitudinal tracking in a rodent model of Parkinsons disease AUXOLOGICO Biomedical Emerging Technologies and Training in s The new biotechnologies 11 02347867 Treatment of therapy refractory cancer in patients affected by Swachman Diamond syndrome or related inherited diseases due to alterations of the ribosomal apparatus. SAN RAFFAELE Milano Biomedical Genes, Genomes and Genetics Oncology 11 Pagina 34 di 231
02347616 The role of CRPs and SIRTs in modulating cellular stress response after myocardial infarction. SAN RAFFAELE Pisana Roma Biomedical Cardiovascular and Respiratory 11 02350999 Early identification of left ventricular dysfunction due to anthracyclines and target therapy: role of novel imaging techniques and microrna. PASCALE Biomedical Cardiovascular and Respiratory Oncology 11 02346770 Clinical and healthcare strategies for improving quality of life in persons affected by spinal cord injuries: Tuscany regionalnetwork and use of innovative technological devices Toscana Clinical Healthcare Delivery and Methodologies 11 02349125 Follow up study of the relationship between telomere length and the onset of diabetic complications I.N.R.C.A. Biomedical Endocrinology, Metabolism, Nutrition and Reproductive 11 02351193 NETWORK DEGENERATION IN MOTOR NEURON DISEASES (MND): A STUDY OF THE STRUCTURAL AND FUNCTIONAL CONNECTOMES IN AMYOTROPHIC LATERAL SCLEROSIS AND OTHER MND SAN RAFFAELE Milano Clinical Brain Disorders and Clinical 11 02349948 Investigation of genetic molecular mechanisms underlying the risk of cardiovascular events: role of rs5065 human atrial natriuretic peptide gene variant NEUROMED Biomedical Genes, Genomes and Genetics 11 02347894 A new vaccine design to eliminate CCR5 expression and prevent HIV infection SAN RAFFAELE Milano Biomedical AIDS and Related Research 11 Pagina 35 di 231
02351863 Identification of Determinants of Healthy Aging in Italy (IDAGIT) CARLO BESTA Clinical Population and Epidemiology Diseases of environmental origin, with reference also to the workplace 11 02347242 Enhancement of NKG2D ligands induced anti tumor response in Hodgkin and non Hodgkin lymphomas: ERp5 thiol isomerase and ADAM10 disintegrin metalloproteinase as possible therapeutic targets. SAN RAFFAELE Milano Biomedical Immunology Oncology 11 02349443 Integrated diagnostic evaluation of PET/RM and molecular markers in the diagnosis of bone lesions SDN Clinical Oncology 2 Translational Clinical Oncology 11 02348984 Next Generation Sequencing (NGS): from basic research to diagnostic tool for nephrotic syndrome. Puglia Biomedical Genes, Genomes and Genetics The new biotechnologies 11 02350615 Characterization of the role of Mycobacterium avium subspecies paratuberculosis (Map) as a trigger in Type 1 Diabetes Sardegna Biomedical Infectious Diseases and Microbiology 11 02352834 Development and evaluation of Influenza Virus Polymerase Inhibitors for combination antiviral therapy ISS Biomedical Infectious Diseases and Microbiology 11 02347169 MECHANISMS REGULATING DENDRITIC CELL PROTUMORAL ACTIVITY WITHIN THE HYPOXIC MICROENVIRONMENT: POTENTIAL THERAPEUTIC APPLICATIONS IN NEUROBLASTOMA GASLINI Biomedical Oncology 1 Basic Translational Oncology 11 Pagina 36 di 231