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Metabolic Product Category: Metabolic Calcilo XD Updated 5/16/2016

Product Information: Calcilo XD 1 of 4

Nutrition support of infants with hypercalcemia, as may occur in infants with Williams syndrome, osteopetrosis, and primary neonatal hyperparathyroidism, and when a lowcalcium, vitamin D-free formula is needed. Use under medical supervision. No vitamin D. The only commercially available formula for the management of hypercalcemia in infants. Nutritionally complete when prepared as directed, meets the American Academy of Pediatrics Committee on Nutrition recommendations for all nutrients including vitamins and minerals except calcium, vitamin D and phosphorus. Only a minimal amount of calcium (15 mg/100 g powder; 2.9 mg/100 Cal). L-carnitine (7 mg/100 g) and taurine (35 mg/100 g). Eliminates the need to prepare a modular formula. Kosher. Halal. Lactose-free. Gluten-free. Safety Precautions Must be given only to infants whose calcium and/or vitamin D intake must be severely restricted, as in hypercalcemia, and who are under strict medical supervision. Calcium, vitamin D and phosphorus requirements should be determined by appropriate laboratory tests. This formula does not supply the minimum recommended intake of calcium, vitamin D or phosphorus for normal infants. Not for IV use. Never use a microwave oven to warm formula. Serious burns can result. Powdered infant formulas are not sterile and should not be fed to premature infants or infants who might have immune problems unless directed and supervised by your baby's doctor. Ingredients Powder Unflavored: Corn Syrup, Coconut Oil, Corn Oil, Whey Protein Concentrate, Sodium Caseinate. Less than 1.0% of: Potassium Phosphate, Magnesium Chloride, Potassium Chloride, Potassium Citrate, Ascorbic Acid, m- Inositol, Salt, Choline Chloride, Ferrous Sulfate, Potassium Hydroxide, Taurine, Zinc Sulfate, L-Carnitine, d-alpha-tocopheryl Acetate, Niacinamide, Calcium Pantothenate, Vitamin A Palmitate, Cupric Sulfate, Thiamine Chloride Hydrochloride, Riboflavin, Pyridoxine Hydrochloride, Folic Acid, Manganese Sulfate, Potassium Iodide, Phylloquinone, Biotin, Sodium Selenate, and Cyanocobalamin. Allergens: Contains milk ingredients. Availability List Number Item 53328 Calcilo XD Powder / 13.2-oz (375-g) can / 6 ct 2 of 4

Nutrition Information - Powder Unflavored 100 g powder Value %RDI / %DV Value %RDI / %DV Volume, ml 148 Protein, g 2.2 11.4 Fat, g 5.6 28.7 Carbohydrate, g 10.2 52.3 Water, g 134 2.5 Linoleic Acid, mg 1300 6660 Calories 100 513 Potential Renal Solute Load, mosm 18 94 Vitamin A, IU 300 1540 Vitamin D, IU 0 0 Vitamin E, IU 1.9 10 Vitamin K, mcg 8 41 Thiamin (Vitamin B1), mcg 100 513 Riboflavin (Vitamin B2), mcg 150 770 Vitamin B6, mcg 60 310 Vitamin B12, mcg 0.3 1.3 Niacin, mcg 1050 5400 Folic Acid (Folacin), mcg 15 77 Pantothenic Acid, mcg 450 2300 Biotin, mcg 4.5 23 Vitamin C, mg 9 46 Choline, mg 12 62 Inositol, mg 24 123 Calcium, mg 2.9 15 Phosphorus, mg 25 128 Magnesium, mg 6 31 Iron, mg 1.8 9.2 Zinc, mg 0.8 3.8 Manganese, mcg 5 26 Copper, mcg 90 460 Iodine, mcg 6 31 Selenium, mcg 2 10 Sodium, mg 24 125 Sodium, meq 1.0 5.4 Potassium, mg 82 420 Potassium, meq 2.1 10.7 Chloride, mg 57 292 Chloride, meq 1.6 8.2 3 of 4

Preparation Directions for Preparation and Use: Use Only As Directed by a Physician Your baby's health depends on carefully following these directions. Proper hygiene, handling and storage are important when preparing infant formula. Failure to follow these directions could result in severe harm. Ask your baby's doctor if you need to use cooled, boiled water for mixing and if you need to boil (sterilize) bottles, nipples and rings before use. Wash your hands, surfaces and utensils. Pour prescribed amount of water into a clean bottle (see mixing guide). Add 1 unpacked level scoop (8.6 g) to each 2 fl oz of water Return dry scoop to can. Cap bottle; shake well; attach nipple. Once feeding begins, use within 1 hour or discard. Mixing Guide Measure Water Add scoop(s) ofunpacked level powderusing enclosed scoop 2-fl-oz 1 scoop (8.6 g) 2 fl oz 4-fl-oz 2 scoops 4 fl oz 6-fl-oz 3 scoops 6 fl oz Finished Bottle (approx) To make a larger amount of formula at standard measuring cup, add 1 unpacked, level cup (NOT the enclosed scoop) of powder (105 g) to 24 fl oz of water. Yields approximately 26 fl oz of formula. To maintain freshness, pour prepared formula into individual feeding bottles, cap and store in refrigerator. Prepared formula should not be left unrefrigerated. When mixed as directed, the contents of one can (375 g) will make approximately 96 fl oz of formula at 20 Cal/fl oz. Storage & Handling Powder Once mixed, store bottles or container in refrigerator and feed to baby or child within 24 hours Store unopened or opened can at room temperature; avoid extreme temperatures. Use opened can contents within 1 month. 4 of 4