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HONORS BIOLOGY CHAPTER 8 STUDY GUIDE Name Period READ pp. 126-7 Cell Division On the blanks write AR for asexual reproduction and SR for sexual reproduction: 1. requires two parents 2. the offspring are identical to the parents 3. parents are gametes 4. have a single parent 5. growing a plant from a plant clipping 6. growing new skin cells 7. forming a zygote 8. What is the difference between mitosis and binary fission? 9. How can the two daughter cells be identical if the cells split into two cells? READ p. 128 Eukaryotes and Prokaryotes 1. Fill in the chart comparing eukaryotic and prokaryotic cells. PROKARYOTIC CELLS Relative size EUKARYOTIC CELLS Typical cell number of genes Relative number of chromosomes 2. Match the chromosomal terms: a. structure joining two sister chromatids A. sister chromatids b. loose DNA + protein B. chromosome c. two copies of identical of DNA molecules + protein C. centromere D. single strand of DNA and its protein D. chromatin E. identical offspring after cell division E. daughter cell

Hon Bio Chapter 8 Study Guide p. 2 READ p. 129 Cell Cycle 1. What is an ordered sequence of events that extend from the time a cell is first formed to the time the parent cell divides into two cells? 2. What is another name for the growing stage? 3. What is another name of the stage where everything doubles and divides? 4. Write I for interphase, write M for mitotic phase, and C for cytokinesis: a. cytoplasm divides in two b. high metabolic activity c. additional chromosomes are duplicated d. about 10% of the total time of the cell cycle e. about 90% of the total time of the cell cycle f. contains the G1, S, and G2 phases READ pp. 130-131 Mitosis Write P for prophase, write PM for prometaphase, write M for metaphase, write A for anaphase, and T for telophase. 1. centromeres are lined up at the equatorial plate 2. nuclear envelope forms around the two daughter cells about to form 3. nuclear envelope breaks apart 4. chromatin condenses and visible chromosomes appear 5. centrioles begin to move away from each other 6. centromeres of the sister chromatids break apart 7. this is the phase that is the reverse of prophase 8. sister chromatids form and are attached to centromeres 9. motor proteins powered by ATP move the single chromosomes to the poles 10. spindle microtubules now attach to the sister chromatids throwing them into a dance READ p. 132 Cytokiinesis 1. Sketch how cytokinesis is different in animal cells and in plant cells. Also label the cleavage furrow and the cell plate.

Honors Biology Chapter 8 Study Guide p. 3 READ p. 133 Anchorage Density 1. What type of cells divide frequently? 2. What type of cells do not divide unless the organ is damaged? 3. What type of cells do not divide once formed? 4. MATCH THE TERMS TO THE CORRECT DEFINITIONS: a. a protein secreted by cells to stimulate other cells A. VEGF to divide B. density-dependent inhibition b. stimulates growth of new blood vessels after injury C. growth factor c. promotes rapid growth of connective tissue to D. anchorage dependence seal the wound E. plate-derive GF d. cells must be in contact with a solid surface to divide e. crowded cells stop dividing READ p. 134 Growth Factors 1. What is the purpose of the cell cycle control system? 2. What is the purpose of a checkpoint? 3. Draw the location of the three checkpoints of the cell cycle. Describe what happens at each checkpoint: G 1 G 2 M 4. Which of the checkpoints is probably the most important and why? 5. What does G o mean?

Honors Biology Chapter 8 Study Guide p. 4 READ p. 135 CANCER Match the cancer terms with the definitions: 1. spread of cancer cells beyond original site A. lymphoma 2. cancers that arise from bone and muscle B. malignant tumor 3. abnormally growing mass of cells C. carcinomas 4. cancers from skin or lining of intestine D. metastasis 5. bone marrow cancer E. benign tumor 6. abnormal cells remain at the original site F. leukemia 7. mass has spread into neighboring cells and displace normal G. tumor Function H. sarcoma 8. cancer of the lymph nodes 9. How does the cancer drug, Taxol, work? READ p. 136 MITOSIS OVERVIEW Mitosis provides for what three purposes (see title)? READ p. 136-7 MEIOSIS and Crossing Over 1. What is a somatic cell? 2. How many chromosomes does a human body somatic cell have? 3. How are homologous chromosomes related and different from sister chromatids? 4. What is a locus of a chromosome? 5. How are the sex chromosomes different in male and in females? 6. What are autosomes?

READ p. 137 Gametes Match the terms to the definitions: 1. haploid 2. diploid 3. gametes 4. fertilized egg 5. life cycle 6. double set of chromosomes 7. single set of chromosomes 8. egg and sperm Honors Biology Chapter 8 Study Guide p. 5 A. joining a sperm with an egg B. sex cells C. zygote D. 2n E. n F. stages from adult to adult READ pp. 138-9 MEIOSIS Write the letter that shows the correct phase of each description below: I = interphase A 1 = anaphase I P2 = prophase II T2= telophase II P1 = prophase I T 1= telophase I M2 = metaphase II M1= metaphase I C = cytokinesis A2= anaphase II 1. pairs of chromatids migrate to the poles with attached centromeres 2. the chromosomes duplicate 3. synapsis of the paired chromatids and may result in crossing-over 4. 2 chromatids line up at the equator 5. 4 chromatids line up at the equator 6. centromeres separate as single chromosomes move to each pole 7. cytoplasm divides the cell into two 8. centrioles move toward the poles as chromatids appear as paired with centromeres 9. the nuclear envelope reforms as four daughter cells prepare to form 10. pairs of chromatids are at the poles as new nuclear envelopes form READ p. 140 COMPARING MITOSIS AND MITOSIS (Fill in the chart) Mitosis Purpose Meiosis Make sex cells Chromosomal number of offspring Number of divisions Yield how many cells Have crossing over? haploid Two two Yes

Honors Biology Chapter 8 Study Gide p. 6 READ p. 141 Independent Assortment 1. What is the formula for deciding how many possible total combinations of chromosomes that meiosis and form? 2. Calculate the possible number of combinations if the following haploid numbers are given: n = 2 n = 4 combinations = combinations = READ pp. 142-3 Homologous Chromosomes and Crossing-Over Here is an example of crossing over of homologous chromosomes. You draw your own example. What are recombinant genes? Draw in the chiasma in your diagram above: