DTL AS CROSS-SECTOR TECHNOLOGY PLATFORM



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DTL AS CROSS-SECTOR TECHNOLOGY PLATFORM Enabling next generation life science research workshop Utrecht, October 23, 2013

AN INTEGRATED APPROACH TO BIG SCIENCE & DATA genomics/ngs proteomics metabolomics bioimaging bioinformatics e-science computational systems biology medical informatics experimental technologies big data technologies life science challenges Industrial Biotech Biobased Economy Agrogenomics Horticulture & Starting Materials Health, clinical Life Sciences & Health Nutrition & health Agri&Food

ENABLING NEXT GENERATION LIFE SCIENCE RESEARCH Biomaterial resources High-end wet-lab technologies e.g. next generation sequencing, proteomics, metabolomics, bioimaging Model systems Biotech Health Design of Experiment Agro Scientific Project Research Objective Nutrition Advanced big data technologies e.g. bioinformatics, medical informatics, computational biology & e-science Information & Insight Enabling Next Generation Life Science () cross-technology data integration & system modelling

VISION & MISSION The vision behind DTL is that world-class life sciences technologies will all be readily available to Dutch-based researchers, enabling The Netherlands to become a top-5 country in research by 2020 It is DTLs mission to provide a platform where all public and private stakeholders can bundle their efforts and collaborate to establish a world-class technology infrastructure that facilitates Cross sector exchange of best practices & standards Cross technology data integration Cost effective investments and sustainable facilities Competitive positioning in international programmes

CROSS-SECTOR & CROSS-TECHNOLOGY PLATFORM Nutrition Sector DTL team Clinical & Health Sector DTL team Cross Sector DTL Foundation Team Agro-genomics Sector DTL team Industrial Microbiology Sector DTL team

CROSS-SECTOR & CROSS-TECHNOLOGY PLATFORM Nutrition Sector DTL team Clinical & Health Sector DTL team Cross Sector DTL Foundation Team Agro-genomics Sector DTL team Industrial Microbiology Sector DTL team

CROSS-SECTOR & CROSS-TECHNOLOGY PLATFORM 1. Formal partnership of universities, UMC s, institutes & industry, around DTL foundation 2. Cross sector federation with small organising core link with NFU & Topsector TKI s 3. Association of existing and new technology communities, e.g.: genomics: e.g. NGI centres, TTI s, BBMRI proteomics: NPC, proteins@work metabolomics: NMC bioimaging: NL-bioimaging-AM, EATRIS bioinformatics: NBIC e-science: NLeSC & SURF family comp. systems biology: NCSB, SB@NL 4. Linking with essential infrastructure projects EATRIS, BBMRI, Euro-Bioimaging, Instruct ELIXIR, ISBE, EGI IMI

DTL @ WORK DTL Board Technology Integrator Technology Integrator Technology Technology Integrator Communities Hotel Integrator DTL Director Integrator Office & community support T&E Integrator DTL Foundation Team Sector team Sector team Frank Miedema Kees de Gooijer assembly & CT T&E working group 1. Chain of Technology Hotels 2. : Data Integration & Stewardship 3. T&E: Training & Education 4. -focused Events & Community support 5. Acquisition of technology funds for DTL partners 6. Active involvement of industry Sector team Sector team Ernst vd Ende Karel Luyben

SUMMER 2013: 100 DTL PARTNER APPLICATIONS* Hotels Innovation Labs Service providers BaseClear LIACS LUMC UL Blox Group Leiden Den Haag 16 1 TUDelft Delft 4 5 Rotterdam ErasmusMC Health e-solutions AMC AMOLF CWI NLeSC NKI SURFSARA UvA VU VUMC Amsterdam 20 Utrecht 15 1 TNO Zeist Lelystad 1 Hubrecht Institute SURFnet UMCU UU 10 Wageningen 7 Nijmegen InnoSer NL 9 Groningen Enschede WUR PRI Hanze University RUG UMCG TU Twente Radboudumc Radboud University Microbial Bioinformatics 1 CTMM TUe PHILIPS 6 Eindhoven *) based upon DTL open invitational June 2013 4 Maastricht MAASTRO Maastricht University Scannexus

ACROSS SECTORS Industrial microbiology Biobased Economy (15) Nutrition/ Agri&Food (21) Agrogenomics/ Horticulture & Starting materials (21) Medical&Clinical/ Life Science & Health (79)

ACROSS TECHNOLOGY FIELDS Bioinformatics & Computational biology Genomics Metabolomics Proteomics Bioimaging & phenotyping 1010 1010 1010 1010 1010 10 0101 0101 0101 0101 0101 01 20 8 14 35 60 20 40 60

CHAIN OF > 80 TECHNOLOGY HOTELS* Profiling of technology facilities & communities Exchange best practices & standards Optimise accessibility & Connect in Capability & capacity! Den Haag Delft Leiden 1 4 16 5 Rotterdam Amsterdam 20 Utrecht 15 1 Zeist Lelystad 1 10 Wageningen 7 Nijmegen 9 Groningen Enschede 1 6 Eindhoven *) Accessible in 1st ZonMW/NWO hotel call (Oct. 2013) 4 Maastricht

: DATA INTEGRATION & STEWARDSHIP CENTRE Data Expertise Cross-tech data expert network Four sector-s Data focused T&E Regular technical focus meetings Data Infrastructure Common approach to data (best practices, standards) Harmonised access to data hotels Federated e-infrastructure Data Compliancy e.g. NWO data stewardship connects data workpackages of major ESFRI-NLs

EXAMPLE RED Several health-related data-initiatives stimulated UMC deans to work towards a coordinated research data infrastructure Include beta faculties, NKI, Hubrecht, NFU set up advisory committee Implement inter-umc big-data sharing infrastructure connecting tech hotels, medical research sites, biobanks, plus local & e-science HPC/storage/network Build on CTMM, BBMRI, NBIC, IMI, UMC deans approved goals (sept) Plans now being worked out Red under NFU coordination Link BBMRI-NL2.0, EATRIS-NL, ELIXIR- NL, NL-Bioimaging-AM link to LSH, ZonMW, NWO Life Sciences & Health Plaza

DTL T&E PROGRAMME T&E Working Group established Ambition: international cross-technology training hub! Course directory under construction Searchable overview Links directly to your course website Included are: BSc, MSc, PhD, mentorship/internship, consultancy

DTL T&E: >200 COURSES IN DTL PARTNER GROUPS BaseClear LIACS LUMC UL Blox Group Leiden Den Haag 30 0 TUDelft Delft 12 22 Rotterdam ErasmusMC Health e-solutions AMC AMOLF CWI NCSB NLeSC NKI SURFSARA UvA VU VUMC Amsterdam 58 Utrecht 34 3 TNO Zeist Lelystad 0 Hubrecht Institute SURFnet UMCU UU 24 Wageningen 12 Nijmegen InnoSer NL 10 Groningen Enschede WUR PRI Hanze University RUG UMCG TU Twente Radboudumc Radboud University Microbial Bioinformatics 0 CTMM TUe PHILIPS 27 Eindhoven 4 Maastricht MAASTRO Maastricht University Scannexus

DTL T&E COURSE DIRECTORY V.0.5

YOU ARE DTL DTL is a federation, it is us! Participation possible in all programmes Make sure your organisation becomes a formal partner! We are just starting, please help raise and realise ideas Chain of hotels T&E (http://www.dtls.nl/dtl/coursesubmission) Events:.. November 26: event with FHI