Brain Development Infancy and Early Childhood Phyllis L. LeDosquet Ph.D. University of North Dakota

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Quiz Brain Development Infancy and Early Childhood Phyllis L. LeDosquet Ph.D. University of North Dakota You were born with a predetermined number of brain cells which continually die off through your life. The number of brain cells a person has, determines how much the person knows Brain Facts The adult brain weighs only 3 pounds and is the size of a grapefruit. 78% water 10% fat 8% protein It is so soft, you can cut it with a butter knife Brain Development 15 days gestation brain development begins Ectoderm Outer layer of cells that will mostly be skin 16-20 days- Neural plate forms 21-22 days- Neural tube forms Forebrain, Midbrain, Hindbrain http://faculty.washington.edu/chudler/dev.html Prenatal Brain Development During prenatal development, 250,000 neurons are added to the brain every minute 50,000 cells are added every second. Scheibel Brain stem develops first, then hindbrain, then midbrain. Prenatal Brain Development Growth and development of the brain are genetically determined Environmental factors will however, play a role from the time of conception (Scheibel, 2002).

25 % of its eventual adult size About 3 pounds Already has 100 billion neurons This is twice as many as we need! There are 5-10 X as many glial cells The Infant Brain The most developed region is the brain stem. Synaptogenisis Formation of synaptic connections during development and their modification by experience are important steps in the wiring of the brain. Two kinds of brain cells Glial cells The glue of the brain Makes up 90% of our brain cells Transport nutrients. Substance used for myelination Cleans debris from synapses Neurons The brain s workers They have a body!! Neurons Dendrites Axon Cell Body Synapse Myelinization Myelin Fatty substance that insulate axons Synaptic connections Brain Anatomy 101 Crash Course Increases conduction of nerve impulses from 10-100 times as rapidly as would occur along a non-myelinated axon. A newborn s neurons lack dendrites, synaptic connections and myelin sheath needed for conducting impulses.

Synaptogenisis Dendrites As dendrite branches multiply, they provide an increasing surface area for (synaptic terminals) from other neurons. The larger the number of neuronal connections, the higher the possibilities for neural, and therefore, cognitive activity Axons Variety of lengths, depending on the skill or activity Imagine the length of those in the lower spinal cord of the center for the Lakers Pruning Unnecessary connections are eliminated in order to create a more efficient system Growth and Pruning is dependent on experience Each time a neural pathway is used, it strengthens It becomes strong enough to be immune to pruning Critical Periods of Brain Development There are windows of opportunity The most optimal times for specific brain systems to develop Myelinization Process has a time table 1-3 months Faster for the sensory tract than motor tract 3-6 months Myelinization of cerebral cortex takes place Last Prefrontal lobes (executive functions, intentions, future planning) go into adulthood (Scheibel) 1-3 months Neural connections increase to over 100 trillion Daily verbal interactions Daily physical interactions Routines Feeding, bathing, diaper changes, playing, holding.

3-4 months Fine tuning Parietal Object recognition Eye-hand coordination Temporal Hearing Language Visual cortex Focusing for clearer images 6-7 months Neural connections develop for sound recognition in the native language Doyouwantyourbottle? Becomes Do/ you/ want/your/bottle? Wernickes s Area of Language comprehension Auditory cortex Broca s Area 8-9 months Hippocampus becomes fully developed Memories Emotions 12 months Brain consumes twice as much energy as the adult brain Prefrontal cortex develops synapses at a rapid rate Forethought and logic 18 months Neural connection s have increased and strengthened Information transfer is efficient Language explosion takes place Full cortex is involved in language development Toddlers can learn up to 12 words a day (fast mapping) One Year of Age Has a greater density of synaptic connections than the adult brain The smarter we are the more synaptic connections we have. 2 years of age Fully wired brains Greater maturity in motor areas Physical ability exceeds common sense

What can we do? Shape the environment Attachment Novelty Activity Nutrition Studies Marian Diamond (1998) University of California, Berkeley Studied brain development in rats (40 yrs) Impoverished Food, water, cage Enriched Food, water, cage, toys, wheels, trails and climbing blocks Rats in enriched environments had more dendritic connections, dendrites were also thicker Sprenger, M.1999. Learning and Memory. The Brain in Action. Association for Supervision and Curriculum Development William Greenough University of Illinois Same experiment Rats in Rat Disney Land had 25% more connections In four days, dendrite growth was evident as was dendrite death. Sprenger, M.1999. Learning and Memory. The Brain in Action. Association for Supervision and Curriculum Development Diamond (1985) Baby rats and mature rats Mature rats dominated and wouldn t let the baby rats play Only the mature rats grew dendrites It isn t enough for them to be in the enriched environments, they have to actively interact with it What do we do in our classrooms? Sprenger, M.1999. Learning and Memory. The Brain in Action. Association for Supervision and Curriculum Development

Craig Ramey, University of Alabama Experimental and Control Groups of children 6 months of age Followed for 12 years Experimental Playmates, good nutrition, learning and play opportunities Control Stayed within inner-city impoverished environments Significantly higher IQs in experimental group 12 years later Sprenger, M.1999. Learning and Memory. The Brain in Action. Association for Supervision and Curriculum Development IQs of nursing home residents People in nursing homes have significantly lower IQs than those waiting to be admitted to nursing homes. IQs changed significantly after 6 months in the nursing home. Sprenger, M.1999. Learning and Memory. The Brain in Action. Association for Supervision and Curriculum Development Activity Crawl Time Why does exercise increase neuron growth? Studies show impact of motor stimulation on reading, writing, attention 1960 2-year-old had spent an average of 200 hours in a car. Today 2-year-old has spend an estimated 500 hours in a car seat. Jensen, E. 1998. Teaching with the brain in mind. Association for Supervision and Curriculum Development. Virginia. The Visual Brain Children need a flood of information, a banquet, a feast. Martha Pierson, Baylor College of Medicine (1996) Television is 2 dimensional The Brain needs depth Some researchers believe television should be banned for children under 8 years of age. Healthy Environments Muddy synapses Sleep, Food, Water Dehydration We are thirsty because of a drop in water content in our blood When water drops, salt concentration increases which increases the release of fluid from cells

This raises blood pressure and stress levels Within 5 minutes of drinking water, there is a decline in corticoids and ACTH (stress hormones) Nutrition affects development What did we eat? 65% of nutrition came from fruits, vegetables, nuts, legumes, and honey What do we eat now? 17% of our nutrition comes from fruits, vegetables, nuts, legumes and honey. Modern diet it made up of cereals, grains, milk, dairy products, sugar, fats and alcohol. Animal Fat Stunts cell growth Promotes poor dendrite growth Creates brain short circuits Dries up neurotransmitters Starves cerebral tissue Impairs learning Omega-6 Inflammatory affect on neurons It lights a fire throughout the brain Foods with Omega-6 Processed foods Vegetable oils (corn, safflower, sunflower) Pastries and baked goods Omega-3 Fats (fish) Mackerel, herring, sardines, salmon, white tuna, swordfish, haddock Keep cells soft and flexible Improves memory Regulate serotonin levels Is ADD an Omega-3 deficiency? Is Dyslexia an Omega-3 deficiency? The Smart Drug (Blood Sugar) Energy Good mood Concentration Memory Glucose

Can they raise the IQ? Vitamins It s not that vitamins increase intelligence. It s that a poor diet lowers performance on intelligence tests Vitamin C The brain saver The smart pill It can directly influence electrical impulses, the synthesis of and release of neurotransmitters citrus fruits, broccoli, tomatoes, melons, dark green leafy vegetables, cabbage, strawberries, potatoes Thiamin Is known to control mood Overall brain improvement Study on children Increase in reaction time, intelligence, visual acuity and memory pork, organ meats, legumes, nuts, whole grains, enriched cereal Where do we go from here? References Christie, J., Enz, B., Vuchelich, C.2003. Teaching Language and Literacy; Preschool through the Elementary Grades 2nd Ed. Boston. Pearson Education Inc. Jensen, E. 2000. Teaching with the Brain in Mind. Alexandria, Virginia. Association for Supervision and Curriculum Development. Carper, J. 2000. Your Miracle Brain. New York. HarperCollins Publishers. Papalia, D. E., Wendkos Olds, S., Feldman, R. D. (2004). A Child s World 9th ed, New York. McGraw, Hill Co. Scheibel, A.B.(2002) Embryological Development of the Human Brain. Seattle Wa. New Horizons for Learning. Website: Neuroscience for Kids. http://faculty.washington.edu/chudler/neurok.html