Important Information About Your Empower 3 Software Upgrade

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Important Information About Your Empower 3 Software Upgrade OPERATING SYSTEMS AND COMPUTER CONFIGURATION SPECIFICATIONS Empower 3 Software is tested on the system configurations detailed below. These are the recommended minimum computer configurations required to run Empower 3 Software. Please note that these recommendations do not take into account additional hardware requirements necessary to run other applications on the same system used to run Empower 3 Software. Refer to the Microsoft hardware compatibility list for a definitive statement on specific models of computers supported. All configurations of Empower 3 Software require a DVD drive. Computer Configuration Memory (minimum) Hard Drive Total/Free (minimum) Processor (minimum) Operating System Oracle Database Oracle Client Personal Workstation Client or LAC/E 32 Module Windows Database Server Citrix Server (XENAPP Server 6.0) 4 GB 4 GB 6 GB 2 GB 25/20 GB 25/20 GB 25/22 GB 8 GB Core2 Duo E6400 Professional 64-bit Core2 Duo E6400 Professional or Enterprise; Windows XP Professional or Enterprise None Intel Xeon 2 GHz (single or dual) Windows Server 2008 R2 Enterprise 64-bit 64-bit Windows Server 2008 R2 Enterprise 64-bit None Internet Explorer 8.0 8.0 8.0 8.0 buslac/e INTERFACE CARD The ISA buslac/e Interface Card is not supported in Empower 3 Software.

LAC/E 32 MODULE Refer to the chart below to determine the compatibility of LAC/E 32 modules with the operating system you plan to use. Please contact your local Waters representative to learn about our convenient upgrade and trade-in programs. LAC/E 32 configurations 10-15 supported LAC/E 32 configurations 10 and 11 are supported with Windows XP only LAC/E 32 configurations 12, 13, and 14 are recommended to be run with LAC/E 32 configurations 10 and 11 need additional memory 2 GB minimum LAC/E 32 configuration 15 is supported with only LAC/E 32 Configuration # LAC/E 32 Serial Number Range Supported Operating System 10 C05L32275W and higher Windows XP 11 All Windows XP 12 All 13 All 14 All (recommended) or Windows XP (recommended) or Windows XP (recommended) or Windows XP Memory Upgrade Required (2 GB recommended) Yes, replace original 512 MB RAM (two 256 MB sticks) using four 512 MB sticks. Upgrade Kit 668000365 contains two 512 MB sticks (purchase 2 kits/lac/e 32 ). Yes, add two 512 MB sticks to original 1 GB RAM (two 512 MB sticks). Upgrade Kit 668000366 contains two 512 MB sticks (purchase 1 kit/lac/e 32 ). 15 All No No No No Empower 3 Software does not support the following instruments: 700, 710, 712, and 715 Autosamplers 410 RI Detector 474 Fluorescence Detector 484, 486, 490 UV Detectors 990/991, 996 PDA Detectors LC Module 1 GPC 2000 Integrity TMD 5890 GC (under buslac/e control) 7673 (under buslac/e control) SIM System Interface Module 2

EMD Support for the EMD will be on Windows XP only. There will be no EMD support for the Empower 3 Personal platform. ZQ Support for the ZQ 2000 and ZQ 4000 will be on Windows XP only. There will be no ZQ support for the Empower 3 Personal platform. EQUINOX 8-PORT SERIAL CARD The Equinox 8-Port Serial Card is only supported on Windows XP. Current serial instrument support using the Equinox 8-port card is: Agilent 5890 GC (5890S) Agilent 7673 GC Autosampler (7673S) Agilent 6890 GC (all models, including 6890N) Agilent 6850 GC (serial number less than or equal to 00003200) Agilent 7694 Headspace Sampler (G1289B and G1290B) Waters bussat/in Module Agilent A1100 LC Modules (not A1200 modules) AVOCENT 8-PORT SERIAL HUB Current serial instrument support using the Avocent 8-Port Serial Hub is: Agilent 5890 GC (5890S) Agilent 7673 GC Autosampler (7673S) Agilent 6890 GC (all models, including 6890N) Agilent 7694 Headspace Sampler (G1289B and G1290B) Waters bussat/in Module Agilent A1100 LC Modules (not A1200 modules) 3

Instrument Firmware Version ICS Version Comments ACQUITY UPLC Sample Manager (SM) 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC Binary Solvent Manager (BSM) ACQUITY UPLC Sample Organizer (SO) 1.40 N/A ACQUITY UPLC 2996 4.2 N/A 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC TUV 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC Column Manager 1.40, 1.45 1.40, 1.45 Firmware delivered with ICS ACQUITY UPLC Column Calculator 1.45 1.45 Firmware delivered with ICS ACQUITY UPLC SQD 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC TQD 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC 3100 1.40 1.32 Firmware delivered with ICS ACQUITY UPLC Column Heater/Cooler N/A N/A ACQUITY UPLC FLR 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC ELS 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC PDA 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC epda 1.40 1.40 Firmware delivered with ICS ACQUITY UPLC Sample Manager FTN 1.45, 1.46 1.45, 1.46 Firmware delivered with ICS ACQUITY UPLC QSM 1.45, 1.46 1.45, 1.46 Firmware delivered with ICS ACQUITY UPLC HandHeld 1.46 1.46 Firmware delivered with ICS e2695 Alliance 3.00 N/A e2695d Alliance HPLC Dissolution 3.00 N/A e2795 Alliance 3.00 N/A W2695 Separation Module 2.04 N/A W2795 2.05 N/A W2795D 2.04 N/A Alliance Column Heater N/A N/A Alliance Column Heater/Cooler N/A N/A ZQ (2000 and 4000) Empower 3 1.01 Communication/Control via ethernet (Windows XP only) W600 LP/LCD A/C Power 3.5 N/A W600S (W616/626) LP/LCD A/C 4.2 N/A W717plus 3.1 N/A Prep 2000/4000 3.1 N/A PCM/PCM II 2.2 N/A TCM/TCM II 2.1 N/A 1515/1525 2.2 N/A W2996 3.5 N/A W2998 1.40 1.30 W2410 5.1 N/A Shows up as 410 W2414 1.0 N/A 2410 emulation mode 4

Instrument Firmware Version ICS Version Comments W2420 Firmware delivered with ELS ICS. See Waters ELS. W2424 Firmware delivered with ELS ICS. See Waters ELS. W2465 2.0 1.00 W2475 2.01 1.01 Supported on Avocent and ethernet W2487 1.01 N/S W2489 1.40 1.31 EMD 1000 1.00 1.00 Firmware delivered with ICS. Windows XP support only. 2700 2.2 N/A W2707 1.12 1.20 A1100/A1200/A1260/A1290 using Agilent ICF support See Agilent for ICF compatibility Waters ICF Support v2.1 Hotfix 1, Agilent ICF version A.01.05 SP1 A1100/A1200 A.06.10.07, B.06.01 1.06.1007 A5890S A.03.02 N/A S designates instrument on serial card (Avocent) A7673S, G1512 4.3 N/S S designates instrument on serial card (Avocent); Dual Tower Injections supported on serial card (Avocent) A6890/6890+ A.03.07, A.03.08 N/A RS232 serial connection 6890 N N.05.05, N.06.07 N/A RS232 serial connection A6850 Network GC System A.05.04, A.06.02 1.30 Serial numbers greater than or equal to 10243001; Ethernet connection A6850 Series II Network GC System A.05.04, A.06.02 1.30 A6850 Series GC System A.03.03, A.03.07 1.30 Agilent 7890A GC System Agilent 7890B GC System A.01.10.3, A.01.11.1, A.01.12, A.01.12.1, A.01.13 B.02.00, B.02.01, B.02.02 G1888A Headspace Sampler A.01.09 2.00 Serial numbers greater than or equal to 10243001; Ethernet connection Serial numbers less than or equal to 00003200; RS232 serial connection 2.50 Firmware version A.01.11 is not supported 2.50 Operates as a 7890A HS7694 Headspace Sampler 1.05 2.00 G1289B and G1290B 2535 QGM 1.10 1.10 2545 QGM 1.10 1.10 2555 QGM 1.10 1.10 Data Acquisition Firmware Version ICS Version Comments Half-size PCl buslac/e Board REV. A N/A Avocent 8-Port Serial Hub 6.0.0.3 N/A Windows XP or Windows 7 SAT/IN 13.0/20.0 N/A Supported on buslac/e only SAT/IN2 13.0/20.0 N/A e-sat/in 2.5, 2.6, 3.1, 3.2 1.30 SAT/IN2 is used to designate the bussat/in module when used with a PC COM port, an Equinox Card, or an Avocent Hub Equinox Serial Card 5.41.0.0 N/A Support on Windows XP only 5

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