Medication Delivery BreatheRite VHC

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Medication Delivery BreatheRite VHC The BreatheRite Valved Holding Chamber (VHC) from Ventlab combines design advantages with portability to provide both effective medication delivery and potentially increased patient use. The anti-static VHC is available in a rigid and collapsible version. BreatheRite is non-sterile and latex free. For detailed product information, visit www.ventlab.com or contact your Ventlab Sales Representative. BR302-I Rigid VHC with Small Adult Premium Eco Mask Geometrically correct chamber allows for natural expansion of medication plume Inspiratory aperture promotes proper inspiratory rate Face Mask Options: Economy Spacer Mask Inflatable Vent Mask 22mm OD mouthpiece fits most face masks Low resistance exhalation valve angles away from patient s face Collapsible version makes it portable, promoting patient use Premium Eco Mask, PVC-Free MDI port BreatheRite: More Efficient Medication Dispersion Multiple independent comparative studies* of the BreatheRite Spacer and the leading valved holding chamber measured aerosol particle size and output efficiency. The study tested three drugs on both devices. Results showed that the BreatheRite VHC performed 42% more efficiently than the leading valved holding chamber. *A Lung Model Comparison of the Aerochamber and BreatheRite MDI Spacers in the Delivery of Albuterol to an InVitro Lung Model. J.B. Fink, B.S., R.R.T.; H.L. Phelps, R.R.T.; J.L. Skolnick, M.D.; P.B. Cerrito, Ph.D.; Heart and Lung Institute, Jewish Hospital, Louisville, KY. Particle Size and Output Comparison of the BreatheRite and AeroChamber Aerosol Holding Chambers. R.J. Perry, B.S.; W. Chiang; J.S. Ilowite, M.D.; SUNY at Stony Brook, NY 11794, California Measurements, CA 91024 and Winthrop-University Hospital, Mineola, NY 11501. Anti-Static BreatheRite Valved Holding Chamber Anti-static chamber enables effective medication delivery Designed to promote greater drug volume output Inspiratory aperture ensures proper inspiratory rate Chamber design eliminates the need for a flow signal since whistling signals are shown to confuse users Collapsible version makes it very portable Face mask (all detachable) options available Rigid Cat# Mask Type Mask Size Box BR300 No Mask - VHC Only 20 BR310 Economy Spacer Mask Adult 20 BR320 Economy Spacer Mask Pediatric 20 BR330 Economy Spacer Mask Infant 20 BR301 Inflatable Vent Mask Small Infant 20 BR302 Inflatable Vent Mask Infant 20 BR303 Inflatable Vent Mask Small Child 20 BR304 Inflatable Vent Mask Child 20 BR305 Inflatable Vent Mask Adult 20 BR302-I Premium Eco Mask Small Adult 20 BR303-I Premium Eco Mask Medium Adult 20 BR304-I Premium Eco Mask Large Adult 20 Collapsible Cat# Mask Type Mask Size Box BR200 No Mask - VHC Only 20 BR210 Economy Spacer Mask Adult 20 BR220 Economy Spacer Mask Pediatric 20 BR230 Economy Spacer Mask Infant 20 BR201 Inflatable Vent Mask Small Infant 20 BR202 Inflatable Vent Mask Infant 20 BR203 Inflatable Vent Mask Small Child 20 BR204 Inflatable Vent Mask Child 20 BR205 Inflatable Vent Mask Adult 20 BR202-I Premium Eco Mask Small Adult 20 BR203-I Premium Eco Mask Medium Adult 20 BR204-I Premium Eco Mask Large Adult 20 2710 Northridge Drive I Suite A I Grand Rapids, MI 49544 800-593-4654 I www.ventlab.com BreatheRiteVHC Rev. 1 / Page 1

Introducing pmdi Guidance System Mouthpiece Patent Pending Guidance Grip Technology Straight Forward Delivery Guidance Coneoval Shape Rolled Coneoval Edge Vertical Preference Horizontal Preference The InFloCone (IFC) disposable mouthpiece is designed to simply and economically provide the user with consistent and efficient delivery when inhaling pressurized, metered dose medications. The IFC will help to avoid the random mishaps and effects of medicine spray into your face. It will also allow the momentum of high speed propelled aerosol to slow as you inhale while adding a degree of repeatability to the delivery of each dose. No More Spray-In-The-Face. Straight-Forward Guidance. THE BENEFITS: Guidance Grip Technology: One size fits all. Coneoval Shape: Pre-set open mouth for consistent delivery. Rolled Coneoval Edge: For a confident seal with your lips. Straight-Forward Delivery Guidance: Aids coordination so user can concentrate on inhalation technique. IFC allows for propelled medication to be received more slowly. Economical: Smaller size and lower cost help to build compliance and adherence to therapy. Discreet, Compact, Simple Appearance: Easy to use whenever you need, wherever you are. Without InFloCone. With InFloCone. THE CHALLENGE: What strategies are you using to combat high readmission rates? Studies show as many as 79% of COPD patients misuse their inhaler.* Use InFloCone Privately or... While Active. *Pittsburgh Regional Health Initiative and Center for Healthcare Quality and Payment Reform 2008-2011 Scan this QR code now or visit www.inflocone.com for instructional video.

DATA/SPECIFICATIONS PROTOCOL: Aerosol Performance Testing of InFloCone and Commercial MDI - Ventolin HFA RESULTS Aerosol Performance Comparison of InFloCone and Commercial MDI Particle Geometric Total Dose Total Coarse Fine Ultra-Fine Size Standard Delivered Respirable Particle Particle Particle (MMAD) Deviation by Device Dose (0.5-5 um) Dose (>4.7 um) Dose (<4.7 um) Dose (<1.0 um) (um) (ug/burst) (ug/burst) (ug/burst) (ug/burst) (ug/burst) InFloCone w Ventolin HFA 1 2.0 2.2 67.4 43.4 23.9 43.4 9.5 2 1.9 2.1 70.0 44.9 24.1 45.9 9.7 3 1.7 2.1 71.7 47.8 21.2 50.5 13.6 Mean 1.87 2.14 69.7 45.4 23.1 46.6 10.9 Std Dev 0.15 0.05 2.2 2.2 1.6 3.6 2.3 Commercial MDI Ventolin HFA 1 1.9 3.2 104.7 39.4 58.4 46.4 17.4 2 1.7 2.5 102.9 46.9 51.8 51.1 18.0 3 1.8 3.3 103.8 40.2 57.1 46.6 17.5 Mean 1.80 2.99 103.8 42.2 55.7 48.0 17.6 Std Dev 0.10 0.40 0.9 4.1 3.5 2.7 0.3 Statistical Analysis Mean D 0.07 0.85 34.1 3.2 32.7 1.4 6.7 T Stat. 0.63 3.62 25.02 1.18 14.58 0.56 5.00 T (p=0.05) 2.78 2.78 2.78 2.78 2.78 2.78 2.78 Sig? NO YES YES NO YES NO YES Table 1 showing the performance of the InFloCone with Ventolin HFA as compared to the Ventolin HFA commercial MDI by itself. The statistical analysis shows there was no measurable difference in the two for particle size, respirable dose and fine particle dose. Clinical Data: Piper Medical, Carmichael, CA DISPOSAL/CLEANING The InfloCone should be disposed of with the exhausted MDI it is being used with. While in use it can be cleaned with warm water and soap and air dried. ORDERING INFORMATION Description Quantity Part # InFloCone in polybag Box of 50 1357050 w/instructions for use Alliance Tech Medical, Inc. PO Box 6024 / Granbury, TX 76049 1.800.848.8923 / 817.326.6357 Fax: 817.326.2182 / www.alliancetechmedical.com Eastern Office 302.838.2638 Central Office 800.848.8923 Southern Office 817.326.3183 Western Office 800.848.8923 2015 Alliance Tech Medical, Inc.

Pulmonary Function Filters Filters provide variety, ease-of-use and affordability. Available with round or oval patient side mouth ends Introducing All FLOW filters meet or exceed the highest standards in PFT filtering with minimal resistance and low dead space. Our Port Color Variety (PCV) reduces contamination risk with filter mounting. The distinguishable color provides correct connection with equipment the first time. Quality spirometry and lung function tests are accurately obtained with 8 individual port sizes. The All FLOW filter medium traps bacteria and viruses efficiently with electrostatic properties. Low Resistance Minimal Dead Space Unique filter design accommodates Small Mouth Adapter for adults and children without compromising filter function 99.99% bacterial and viral filtration 8 standard port sizes defined by color designed to fit a wide selection of equipment. Filters exceed ATS guidelines for all criteria Connect with us online www.alliancetechmedical.com

Ordering Information Port Side Color Manufacturer Cross Fillter OD ID Quantity Shape Order# NHRIC#/NDC Grey InCheck, InCheck DIAL, Multispiro, 30 26.3 100/box Round 5551100 10 38462551100 2 CreativeBiomedics, Vitalograph, Schiller, MicroDirect, Oval 7771100 10 03846277110 4 SDI (Pulmogard II ), Most CosMed Models, MIR (All Models), P.K. Morgan 232, Future Med (Spirobank), PB-400, PB-600, CDX Spiro 850, Spirometrics (Flowmate, Flowmate+,SMI I, Vacumed (Micro, Micro Plus, Micro GP-GL, Micro Loop, Pony) Red Brentwood, Burdick, and most Fukuda 43.5 40 100/box Round 5552100 10 38462552100 1 Models, Spirometrics (some models) Orange Koko, KoKo Legend, Keystone, 48.5 45 100/box Round 5553100 10 38462553100 0 Koko-Trek, CyberMedic Full Gas Systems, Oval 7773100 10 38462773000 8 Collins 4G and 3G Full Gas Systems. Medium Blue SensorMedics, 2200,2400, 2450, 2800, others, 34 30 100/box Round 5554100 10 38462554100 9 Including Vmax, Keystone I & II, Oval 7774100 10 038462774105 Pail, Cybermedics Moose, Gould 5004 Medium Green Jaeger Models 33.5 30 100/box Round 5555100 10 38462555100 8 Oval 7775100 10 03846277510 2 Yellow Collins DC-2 28.3* 28.7 100/box Round 5556100 10 38462556100 7 Oval 7776100 10 03846277610 9 Bright Green Jaeger Master Screen Series, New 32.5 29.7 100/box Round 5558100 10 38462558100 5 Oval 7778100 10 03846277810 3 Blue-Grey MedGraphics prevent 37.95 34.60 100/box Round 5559100 10 38462557100 6 (with 34.8 undercut) Oval 7779100 10 038462779100 * 2 Step Port Side, Stepped up to 34.8 for Collins Equipment Port Side Color Filter Kit Quantity Order# NHRIC#/NDC Grey 1000 filter with noseclip & mouthpiece 50/box 5551595 50 38462551595 4 Orange 3000 filter with noseclip & mouthpiece 50/box 5553595 50 38462553595 2 Medium Blue 4000 filter with noseclip & mouthpiece 50/box 5554595 50 38462554595 1 Medium Green 5000 filter with noseclip & mouthpiece 50/box 5555595 50 38462555595 0 Yellow 6000 filter with noseclip & mouthpiece 50/box 5556595 50 38462556595 9 Bright Green 8000 filter with noseclip & mouthpiece 50/box 5558595 50 38462558595 7 All Filter Kits Contain Filter, Nose Clip & Disposable Latex Free Mouthpiece Specifications: Bacterial & Viral Filtration Efficiency: 99.99% Dead Space: Resistance: Material: Approx. 35ml (cc) 0.23 cm H 2 O/L/sec approx. K resin case Electrostat fitrate medium Description Quantity Order# NHRIC#/NDC Padded Nose Clip 100/bag 5550047 3 8462550047 4 Latex Free Rubber Disposable Mouthpiece 50/box 5550050 3 8462550050 1 Small Mouth Adapter 100/box 3122220 3 8462122220 2 Filter-Fit Disposable 100/bag 3125500 Cardboard Mouthpiece Distributed By: Alliance Tech Medical, Inc. PO Box 6024 / Granbury, TX 76049 1.800.848.8923 / 817.326.6357 Fax: 817.326.2182 / www.alliancetechmedical.com Eastern Office 302.838.2638 Central Office 800.848.8923 Southern Office 817.326.3183 Western Office 800.848.8923 2015 Alliance Tech Medical, Inc. SAM015 2/15

Contact: Carolyn Ellema Trimedco 800.873.0859 Filter Order Numbers Add NW (Standard Mouth) SW (Small Mouth) EW (Elliptical) 100756 (OD 48.6mm x ID 45.5mm) Fits: Koko, Koko Legend, Keystone, Koko-Trek Cybermedic Full Gas Systems, Collins 3G and 4G Full Gas Systems, Spirometrics 100757 (OD 34.3mm x ID 30.0mm) Fits: Sensormedics & Vmax, Keystone I & II, Cybermedics Moose, Gould 5004, Jaeger Models 100758 (OD 28.4mm x ID 26.4mm) Fits: Collins DCII, Ferraris, nspire Health 100759 (OD 30.1mm x ID 25.4mm) Fits: Viasys portable Microlab, MultiSpiro, Creative Biomedics, Incheck, CosMed, Vitalograph, Schiller, MicroDirect, SDI Pulmogard II, MIR spirobank & Spirolab, P.K. Morgan 232, Future Med, PB Renaissance II, CDX 850, SMI 100760 (OD 38.8mm x ID 34.5mm) Fits: MedGraphic, Brentwood 4000 100780 (OD 34.3mm x ID 30.8mm) Fits: Morgan Scientific Accessories: 100751 Marshmallow Nose Clip 100754 Latex Free Rubber Mouthpiece Trimedco PFT Filters Low Resistance (0.45cm/H2O/L/S) exceeds ATS Guidelines B/V Filter Efficiency > 99.9% Low Dead Space (53ml) DEHP and Latex Free Available in Standard Mouth, Small Mouth or Elliptical/Tapered Patient End Sold alone or packaged with Nose Clip, Mouthpiece or both Nose Clip and Mouthpieces also sold separately Made in the USA Cost Effective Customer Service 800.873.0859 Fax: 404.351.8831 www.trimedco.com