PRODUCT REFERENCE GUIDE ADVANCED WOUND CARE

PRODUCT REFERENCE GUIDE ADVANCED WOUND CARE

SYSTAGENIX This guide has been developed to provide a useful overview of the products available from Systagenix. Section Let s Heal This section describes our passion and agility to drive innovation that has just one goal: to help heal wounds, fast. This is captured by our call to action: Let s Heal, which represents our unique integrated wound healing portfolio, built of four categories: Section 4 Let s Heal Section 6 Introduction to Diagnostics WOUNDCHEK Protease Status 8 SILVERCEL Non-Adherent Dressing ACTISORB Activated Charcoal Dressing with Silver 12 INADINE Povidone Iodine Non-Adherent Dressing 14 SILVERCEL Hydro-Alginate with silver Section Product Information Guidelines This section includes information on the Systagenix advanced wound care portfolio. It contains details on the technical aspects of the dressings, how the dressings work and the clinical benefits you can expect when using the dressings. You will also find the indications and the specific wound types that the dressings are suitable for. All in one simple, easy place for reference. Section Sizes Codes and Ordering Information This section contains everything needed to order your Systagenix products, including individual sizes and codes available. 16 PROMOGRAN Matrix ORC/Collagen Dressing 18 PROMOGRAN PRISMA ORC/Collagen with Silver/ORC Dressing 20 FIBRACOL PLUS Collagen/Alginate Dressing 22 TIELLE Family: Hydropolymer Adhesive Dressings 26 ADAPTIC TOUCH Non-Adhering Silicone Dressing 28 ADAPTIC Non-Adhering Dressing 30 ADAPTIC DIGIT Non-Adhering Digit Dressing 32 BIOCLUSIVE Transparent Dressing 34 NU-DERM Alginate Dressing 36 NU-DERM Hydrocolloid Dressing 38 NU-GEL Hydrogel with Alginate 40 NU-GEL Wound Dressing 42 DYNA-FLEX Multi-Layer Compression System 44 ALGOSTERIL Calcium Alginate Dressing 46 TRIONIC Alginate Dressing with calcium, zinc & manganese ions 48 N-A and N-A Ultra Dressing Section 50 Sizes Codes and Ordering Information 2 Introduction Contents 3

Let s Test To finally provide wound care tools which aid a correct and timely diagnosis, just like other areas of medicine nowadays. WOUNDCHEK Protease Status Let s Protect To protect from infection, SILVERCEL NON-ADHERENT whilst also managing the secondary symptoms of Exudate, Pain, and Odour. SILVERCEL NON-ADHERENT with EasyLIFT SILVERCEL ACTISORB INADINE Let s Promote PROMOGRAN PROMOGRAN PRISMA To promote wound healing in ways that standard dressings may not be able to. PROMOGRAN PROMOGRAN PRISMA FIBRACOL PLUS Let s Comfort To provide a comfortable and effective healing environment for all types TIELLE of wounds. ADAPTIC TOUCH TIELLE Family with LiquaLock ADAPTIC Family BIOCLUSIVE NU-DERM Alginate NU-DERM Hydrocolloid NU-GEL Hydrogel NU-GEL Wound Dressing ALGOSTERIL TRIONIC N-A and N-A Ultra DYNA-FLEX 4 Section Let s Heal Section 5

Welcome to 21st century wound care The development of specific diagnostic tests for use in wounds has the potential to revolutionise their treatment, and help improve standards of wound care (while) aiding in the cost effective use of limited resources. World Union of Wound Healing Societies. Principles of best practice: A consensus document: MEP Ltd. London, 2008. IMAGINE A WORLD WITHOUT WHEELS Research suggests that wounds that heal well have a lower overall Protease activity than those that heal poorly. As a result, a test that readily provides this information might be clinically useful in understanding how well a wound is healing, and whether an intervention that modulates Protease activity may be needed. SOON YOU WON T BE ABLE TO IMAGINE A WORLD WITHOUT 6 Section Product Information Section 7

SILVERCEL NON-ADHERENT SILVERCEL NON-ADHERENT Dressing SILVERCEL NON-ADHERENT Dressing is the next generation of Silver Antimicrobial Dressing with the unique feature of a Non-Adherent layer to maximise protection of the wound bed, particularly at dressing change. The unique composition: a mixture of alginate, carboxymethylcellulose (CMC), and silver coated nylon fibres manages exudate effectively in infected or heavily colonised wounds. The unique EasyLIFT film layer keeps the dressing simple and convenient to use, minimising pain and trauma at dressing change for your patients. SILVERCEL NON-ADHERENT is designed to absorb and retain high amounts of exudate, whilst allowing easy, intact and atraumatic pain free removal from the wound bed. 1 The silver ions within the dressing protect the wound from bacterial contamination. 1 SILVERCEL NON-ADHERENT designed not to stick 1 Maintains a sustained release of silver ions for up to 7 days in vitro 2 Stays strong for intact removal, even when wet Optimally spaced perforations allow free flow of exudate into the dressing, and also ensure the dressing stays intact Conforms to the wound bed for complete coverage when moist, and is designed not to stick to the wound bed at dressing change SILVERCEL NON-ADHERENT has been proven to be 75% Less Adherent than the market leading silver dressing 3 CAD7050 5cm x 5cm (500 eaches) CAD7011 11cm x 11cm 12 (600 eaches) CAD7020 cm x 20cm 5 5 (25 eaches) 8 (200 eaches) CAD7230 2.5cm x 30.5cm 5 5 (25 eaches) 6 (150 eaches) Suitable for use under medical supervision, in the management of infected wounds, or wounds which have an increased risk of infection. May help reduce infection in moderate to heavily exuding partial and fullthickness wounds including: Venous ulcers Donor sites Pressure ulcers Diabetic ulcers Traumatic and surgical wounds 8 Section Product Information References: 1. Clark, R PhD; Stephens, S-A (BSc (Hons); Del Bono, M; Abloye, O; Bayliff, S BSc (Hons); The Evaluation of Absorbent Silver containing Dressings In Vitro; Systagenix Wound Management. Poster Presentation CAWC Quebec City October 2009 2. R.Clark, Michelle Del Bono, Sally-Anne Stephens, Omotayo Abioye, Simon Bayliff: Simulated in use tests to evaluate a Non-Adherent Antimicrobial silver alginate dressing. Presentation Quebec City October 2009. 3. Clark,Stephens,Del Bono: From Lab to Leg The importance of correlating in-vitro and in-vivo test systems to clinical experience. Poster presented SAWC 20. Section 9

ACTISORB ACTISORB ACTIVATED CHARCOAL DRESSING WITH SILVER ACTISORB Dressing consists of activated charcoal impregnated with silver and encased in a nylon sleeve. ACTISORB Dressing is designed to trap wound malodour whilst protecting the wound from infection. By removing harmful elements from the wound, a more stable wound healing environment can be achieved. Activated charcoal traps odour and bacterial toxins 5,6 Binds toxins which are known to impair healing 2 reduces wound odour and improves patient s quality of life Silver Kills bacteria 1 3, 4 reduces infection and exudates Effective wet or dry Consistent adsorption of bacteria ACTISORB Dressing may help to reduce infection in partial and full thickness wounds including: Pressure Ulcers Surgical wounds Diabetic Ulcers First and second degree burns Venous Ulcers MAS065 6.5cm x 9.5cm 28 (1400 eaches) MAS5.5cm x.5cm 9 (450 eaches) MAS190 19cm x.5cm 12 (600 eaches) References: 1. Russel AD et al. Antimicrobial activity and action of silver. Progress in Medicinal Chemistry. 31, 351-370, Elsevier Service 1994 2. Price PE et al. J Wound Care; 9(2):93-95 3. Milward PA. Nursing Times 1991; 87(13):70-72. 4. Leak, K. PEG site infections: a novel use for ACTISORB* Silver 220.Br J Community Nurs. 2002; 7 (6) 5. Kramer A et al Antibacterial activity and endotoxin-binding capacity of ACTISORB* Silver 220. J Hospital Infect. 2003; 53: 511-4. 6. Robson MC et al. Wound healing alterations caused by infection. Clinics in Plastic Surgery 1990; 17: 485-492. Section Product Information Section 11

INADINE INADINE PVP-I Non-Adherent Dressing INADINE PVP-I Non-Adherent Dressing consists of a low adherent knitted viscose fabric impregnated with a polyethylene glycol (PEG) base containing % Povidone Iodine; equivalent to 1.0% available iodine. INADINE Dressings are designed to protect the wound, even if infected. The Povidone molecule provides an effective release of iodine. The polyethyleneglycol provides a water-soluble environment, which allows the Iodine to reach the bacteria in the wound. INADINE Dressing has long been established for use in wound care, its features include: Povidone Iodine controls bacteria by reducing bacterial load and inhibits infection 1-3 1-3 Povidone Iodine is a broad spectrum antimicrobial Safe for use on adults and children and in combination with systemic antibiotics 1-3 INADINE Dressing is designed to protect the wound, even if infected. INADINE Dressing is indicated for the management of ulcerative wounds and may also be used for the prevention of infection in minor burns and traumatic skin loss injuries. P01481 5cm x 5cm 25 (250 eaches) 4 (00 eaches) P01512 9.5cm x 9.5cm 25 (250 eaches) 2 (500 eaches) P01491 9.5cm x 9.5cm (0 eaches) 4 (400 eaches) References: 1. Mclure A.R et al Journal of Hospital Infection. 1992 Aug;21(4):291-9. 2. Goldenheim P.D Postgrad. Med.Jnl.,1993;69 (suppl.3):s97-s5. 3. Adams l. Wound healing altered with the use of povidone iodine. 1985. 12 Section Product Information Section 13

SILVERCEL SILVERCEL Antimicrobial Dressing SILVERCEL is a sterile, non-woven pad composed of a high G (guluronic acid) alginate, carboxymethylcellulose (CMC) and silver coated nylon fibres. The unique composition of SILVERCEL is designed to manage exudate and help control infected or heavily colonised wounds. SILVERCEL has a number of features that can help with controlling Infection: SILVERCEL minimises the risk of maceration and leakage 1, 2 and has been proven to absorb and retain fluid even under compression In vitro studies show that the level of silver released from SILVERCEL is maintained beyond 7 days 3 1,4 Designed not to break up in the wound SILVERCEL maintains its strength within a moist wound environment 1,4 SILVERCEL is intended for use in the management of all moderate to heavily exuding partial and full thickness chronic wounds including: pressure ulcers, venous ulcers, diabetic ulcers, donor sites, traumatic and surgical wounds. As the product contains alginate it may assist in supporting the control of minor bleeding in superficial wounds. It is also suitable for use under medical supervision, in the management of infected wounds, or wounds in which there is an increased risk of infection. CAD050 5cm x 5cm 12 (600 eaches) CAD011 11cm x 11cm 12 (600 eaches) CAD020 cm x 20cm 5 5 (25 eaches) 8 (200 eaches) CAD230 2.5cm x 30.5cm 5 5 (25 eaches) 6 (150 eaches) References: 1. Teot L et al. The management of wounds using SILVERCEL Hydro- Alginate. Wounds UK Supplement. 2005.1(2) 2. Addison D et al. An Antimicrobial Dressing for moderate to heavily exuding infected and critically colonised wounds. Systagenix Wound Management Gargrave U.K. Poster presented at EWMA Pisa May 2003 3. Rennison T et al. Evaluations of a silver Hydro-Alginate dressing to Determine suitability for use on chronic wounds. Systagenix Wound Management Gargrave U.K. Poster presented at EWMA Prague May 2006. 4. Clark R, PhD; Stephens S-A, BSc (Hons); Del Bono, M; Abioye, O; Bayliff S, BSc (Hons). Simulated in-use tests to evaluate a non-adherent antimicrobial silver alginate wound dressing. SAWC, Texas, Dallas 2009 14 Section Product Information Section 15

PROMOGRAN PROMOGRAN Protease Modulating Matrix PROMOGRAN matrix is sterile, freeze-dried composite of 55% collagen and 45% oxidised regenerated cellulose (ORC). PROMOGRAN matrix is designed to promote an optimal healing environment. 1 With PROMOGRAN matrix stalled wounds close: 1,2 Faster 1,3,4 Cost Effectively In the presence of exudate the PROMOGRAN matrix transforms into a soft and conformable, biodegradable gel: this allows contact with all areas of the wound. PROMOGRAN matrix has been proven to reduce levels of Proteases such as MMPs and Elastase. This may restore the balance of the wound microenvironment, promoting granulation tissue and helping the wound close. 5 By reducing both MMP and Elastase activity the wound surface area has been shown to reduce. Collagen alone has been shown to be less effective at reducing protease activity than collagen/orc. PROMOGRAN matrix is indicated for the management of all wounds healing by secondary intent which are clear of necrotic tissue, including: Diabetic ulcers Venous ulcers Pressure ulcers Ulcers caused by mixed vascular aetiologies Traumatic and surgical wounds PROMOGRAN matrix has demonstrated haemostatic properties. PROMOGRAN matrix can be used under compression therapy. M770285 28cm 2 5 8 (40 eaches) 18 (720 eaches) M771235 123cm 2 5 8 (40 eaches) 6 (240 eaches) M772028 28cm 2 4 (40 eaches) 18 (720 eaches) M772123 123cm 2 4 (40 eaches) 6 (240 eaches) References: 1. Lazaro-Martinez et al. Randomized comparative trial of a collagen/ oxidized regenerated cellulose dressing in the treatment of neuropathic diabetic foot ulcers. F.R. Circ. Esp.2007, 82(1), 27-31 2. Veves A et al. A randomized, controlled trial of Collagen/ORC vs. standard treatments in the management of diabetic foot ulcers. Arch Surg 2002;137:822-827 3. Snyder. Sequential therapies and advanced wound care products as a standard practice in the home care setting. Home health abstract for SAWC, San Diego, April 2008 (presentation at the J&J satellite symposium) 4. Ghatenekar O. Willis. M. Persson U. Health Economics. Cost effectiveness of treating deep diabetic foot ulcers with collagen/ ORC in four European countries. J Wound Care, Vol 11, No2. Feb 2002 5. Cullen B, Smith R, McCulloch E, Silcock D, Morrison L. Mechanism of action of Collagen/ORC, a protease modulating matrix for treatment of diabetic foot ulcers. Wound Rep Regen 2002;:16-25. 16 Section Product Information Section 17

PROMOGRAN PRISMA PROMOGRAN PRISMA Matrix Wound Dressing PROMOGRAN PRISMA matrix is a freeze-dried composite of collagen, oxidised regenerated cellulose (ORC) and silver. Made from a matrix of 55% collagen, 44% ORC and 1% ORC/Silver PROMOGRAN PRISMA matrix is designed to kick start the healing process while providing protection from infection. 1-2 In the presence of exudate PROMOGRAN PRISMA matrix transforms into a soft and conformable, biodegradable gel; this allows contact with all areas of the wound. With PROMOGRAN PRISMA matrix see stalled wounds close: 3-5 Faster 3,6 Cost Effectively 7-8 While providing protection from infection PROMOGRAN PRISMA matrix binds and inactivates proteases such as MMPs and Elastase to help rebalance the wound microenvironment, while providing low level silver to help prevent infection. 1-2 By reducing activity of both MMPs and Elastase wound surface area can be reduced. PS2028 28cm 2 4 (40 eaches) 18 (720 eaches) PS2123 123cm 2 4 (40 eaches) 6 (240 eaches) PROMOGRAN PRISMA matrix is indicated for the management of all wounds healing by secondary intent which are clear of necrotic tissue including: Diabetic ulcers Venous ulcers Pressure ulcers Ulcers caused by mixed vascular aetiologies Traumatic and surgical wounds PROMOGRAN PRISMA matrix has known haemostatic properties. PROMOGRAN PRISMA matrix can be used under compression therapy. 18 Section Product Information References: 1. Cullen B et al. ORC/Collagen Matrix Containing Silver Controls Bacterial Bioburden while Retaining Dermal Cell viability. Poster presented at EWMA Prague, May 2006 2. Gregory S et al. The Ability of ORC/Collagen containing silver to reduce Bioburden and retain dermail Cell Viability. Johnson & Johnson Wound Management, Gargrave, UK. Poster presented at ETRS Stuttgart, September 2005 3. Nisi G et al. Use of protease-modulating matrix in the treatment of pressure sores. Chir Ital 2005;57:465-8 4. Lazaro-Martinez et al. Randomized comparative trial of a collagen/ oxidized regenerated cellulose dressing in the treatment of neuropathic diabetic foot ulcers. F.R. Circ. Esp.2007, 82(1), 27-31 5. Veves A et al. A randomized, controlled trial of PROMOGRAN (a collagen/oxidised regenerated cellulose dressing) vs. standard treatments in the management of diabetic foot ulcers. Arch Surg 2002;137:822-827 6. Cullen, B., Domnelly, T., Rennison, T. Can excessive levels of silver be detrimental to healing? SAWC, San Diego, 2008 7. Gregory S et al. The Ability of ORC/Collagen containing silver to reduce Bioburden and retain dermail Cell Viability. Johnson & Johnson Wound Management, Gargrave, UK. Poster presented at ETRS Stuttgart, September 2005 8. Cullen, B., Nisbet, L., Gibson, M., Lanzara, S., Zamboni, P. A clinical study examining the effect of ORC/Collagen/Silver-ORC on healing and wound biochemistry. SAWC, Dallas, 2009 Section 19

FIBRACOL PLUS FIBRACOL Plus Collagen Alginate Dressing FIBRACOL Plus Dressing combines the structural support of collagen with the exudate management of alginate. FIBRACOL Plus Dressing is madeup of 90% collagen and % alginate. Available in selected markets only. The combination of collagen and alginate provides the versatility needed when addressing a variety of wound types and a wide range of exudate levels (from low to high). FIBRACOL Plus Dressing maintains a moist wound environment which is conducive to granulation tissue formation and epithelialisation that enables healing to proceed optimally. FIBRACOL Plus Dressing is indicated for the management of exuding wounds including: Full-thickness and partial-thickness wounds Pressure ulcers Venous ulcers Ulcers caused by mixed vascular etiologies Diabetic ulcers Second-degree burns Donor sites and other bleeding surface wounds Abrasions Traumatic wounds healing by secondary intention Dehisced surgical incisions 2981 2 x 2 12 6 (72 eaches) 15 (80 eaches) 2982 4 x 4 12 6 (72 eaches) 5 (360 eaches) 2983 4 x 8 6 6 (36 eaches) 6 (216 eaches) 2984 40cm (15 X ) 6 6 (36 eaches) 3 (8 eaches) 20 Section Product Information Section 21

TIELLE TIELLE Hydropolymer FOAM dressings The TIELLE Family has a unique design compared to ordinary foams: It contains LiquaLock technology, which cleverly retains exudate while also letting moisture vapour pass through the dressing, helping to provide an optimal moist wound healing environment Managing exudate better helps wounds heal faster and increases patient comfort. For instance, in a clinical evaluation of 6993 patients TIELLE dressings were proven to be clinically efficacious in all wound types studied, with 95% healing or improvement after 4 weeks of treatment, and to improve the patients quality of life 1 The TIELLE Family comes in a wide range of sizes, shapes and absorbencies, allowing you to find a dressing that suits your patients needs Comfort for the wound The TIELLE Family has a pretty unique way of dealing with wound exudate: As exudate is absorbed by the dressing, it is designed to expand and conform to the contours of the wound bed, which helps minimise exudate build-up and the chance of maceration Under normal use, the LiquaLock technology locks fluid into the cell walls, which means reduced potential for it to be released back into the wound 2-4 The vapour-permeable backing allows moisture vapour to transfer through the back of the dressing, allowing for absorption of additional exudate Comfort for the patient The TIELLE Family provides a comfortable solution to meet your patients needs: tielle and TIELLE Plus control leakage and odour for better patient quality of life 1,5 The adhesive variants require no secondary dressing or tape but still allow for skin-friendly removal, due to the unique waterdeactivated adhesive The polyurethane adhesive and backing provide a bacterial and contaminant barrier 6 TIELLE Lite s non-adherent layer ensures less pain on dressing removal, even in bleeding wounds 2 Comfort for you All the TIELLE Family dressings are easy to use: The adhesive dressings allow repositioning as needed on initial application yet stay where placed The non-adhesive dressings are cut-able and can be used for all levels of exudate Comfort for the budget Cost-effective wound care relies on reducing the time to healing, but also on reducing the number of dressing changes needed The superior fluid handling7 of TIELLE Plus and TIELLE Xtra means fewer dressing changes All TIELLE Family dressings provide a wear time of up to seven days depending on wound condition and exudate level 22 Section Product Information Section 23

TIELLE CODE The TIELLE range of dressings is indicated for the management of different types of wounds and exudate levels. TIELLE Xtra is also sold as TIELLE Max and TIELLE S. TIELLE Family Exudate level Adhesive Cut-able TIELLE TIELLE Lite TIELLE Sacrum TIELLE Packing TIELLE Plus TIELLE Plus Sacrum TIELLE Plus Heel TIELLE Xtra 7cm x 9cm 9 (450 eaches) 11cm x 11cm 4 (200 eaches) MTL308 8cm x 15cm 5 (250 eaches) MTL309 8cm x 20cm 5 (250 eaches) MTL0 7cm x 9cm 9 (450 eaches) MTL1 11cm x 11cm 12 (600 eaches) MTL2 15cm x 20cm 5 5 (25 eaches) 5 (125 eaches) MTL3 18cm x 18cm 5 5 (25 eaches) 3 (75 eaches) MTL5 15cm x 15cm 2 (0 eaches) cm x cm 20 5 (0 eaches) 4 (400 eaches) 18cm x 18cm 5 5 (25 eaches) 3 (75 eaches) 9.5cm x 9.5cm 12 (600 eaches) TIELLE MTL1 TIELLE SACRUM MTL301 MTL300 EACHES PER TIELLE LITE SIZE MTL4 TIELLE PACKING MT2450 TIELLE PLUS MTP501 11cm x 11cm 4 (200 eaches) MTP502 15cm x 20cm 5 5 (25 eaches) 4 (0 eaches) MTP505 15cm x 15cm 2 (0 eaches) 5 5 (25 eaches) 4 (0 eaches) 15cm x 15cm 2 (0 eaches) 8 (400 eaches) TIELLE PLUS HEEL MTP508 20cm x 26.5cm TIELLE PLUS SACRUM MTP506 TIELLE MAX MTP701 11cm x 11cm MTP702 15cm x 20cm 5 5 (25 eaches) 5 (125 eaches) MTP705 15cm x 15cm 4 (200 eaches) 8 (400 eaches) TIELLE XTRA References: 1. Evaluation of TIELLE hydropolymer dressings in the management of chronic exudating wounds in primary care. Diehm C., Lawall, H. Int. Wound J. 2005, 2(1):26-35. 2. A non-comparative multicentre clinical evaluation of a new hydropolymer adhesive dressing. Taylor, A., Lane, C., Walsh, J., Whittaker, S., Ballard, K., Young, S.R. J Wound Care 1999, 8():489492. 3. Hydropolymer dressings in the management of wound exudate. Carter, K. Br. J. Comm. Nursing 2003, 8(9) Suppl: -16. 24 Section Product Information MTP301 11cm x 11cm MTP302 15cm x 20cm 5 5 (25 eaches) 5 (125 eaches) MTP305 15cm x 15cm 4 (200 eaches) 4. The Evaluation of Fluid Retention in Foam Dressings, Foster S. and Mistry, P., Wounds UK 20. 5. Clinical evaluation of TIELLE Plus dressing in the management of exudating chronic wounds. Schulze, H.J. Br. J. Comm. Nursing 2003, 8(11):18-22. 6. Boothman S. et al, Bacterial Barrier characteristics of TIELLE to the proposed CEN Test Method, Poster 2002. 7. An evaluation of wound dressings to manage wound exudate and conform to the wound bed, Cullen B. et al, poster SAWC 20. Section 25

ADAPTIC TOUCH ADAPTIC TOUCH Non-Adhering Silicone Dressing ADAPTIC TOUCH Non-Adhering Silicone Dressing is everything you could wish for from a primary silicone wound contact layer and more ADAPTIC TOUCH Non-Adhering Silicone Dressing is non-adherent and flexible with an open mesh comprised of cellulose acetate coated with a soft tack silicone. It is designed to stay in place and to be atraumatic during dressing change. 1,2 Soft tack silicone assists dressing application, conformability and atraumatic removal 1,2 Advanced mesh design means minimised risk of exudate pooling and secondary dressing adherence to the wound 1,2 Ask us about overall cost saving compared to top silicone primary contact layer brands ADAPTIC TOUCH Non-Adhering Silicone Dressing is indicated for use in the management of dry to heavily exuding, partial and full-thickness chronic wounds including: Venous ulcers Decubitus (pressure) ulcers Diabetic ulcers Traumatic and surgical wounds Donor sites First and second degree burns TCH501 5cm x 7.6cm 15 (750 eaches) TCH502 7.6cm x 11cm 12 (600 eaches) TCH503 12.7cm x 15cm 5 (250 eaches) TCH504 20cm x 32cm 5 1 (5 eaches) (50 eaches) It is also suitable for use, under medical supervision, with negative pressure wound therapy (NPWT). 1 References: 1. Stephens S. et al., Evaluation of a non-adhering silicone wound contact dressing with optimised design for the management of dry to heavily exuding wounds (in vitro/vivo). Poster, Wounds UK 20 2. Stephens S. et al., Evaluation of the properties of a non-adhering silicone primary wound contact layer (in vitro). Poster, Wounds UK 20 26 Section Product Information Section 27

ADAPTIC ADAPTIC Non-Adhering dressing ADAPTIC Non-Adhering Dressing is a primary dressing made of knitted cellulose acetate fabric and impregnated with a specially formulated petrolatum emulsion. It is designed to help protect the wound while preventing the dressing from adhering to the wound 1 and to minimise pain and trauma upon removal. 2,3 ADAPTIC Non-Adhering Dressing protects the fragile tissue in wounds by its unique structure with small mesh size, preventing tissue adherence to either the ADAPTIC dressing or the secondary dressing on top of it The mesh allows for exudate to easily pass through to the secondary dressing used, preventing maceration of the wound surface Knitted cellulose acetate fabric allows ADAPTIC Non-Adhering Dressing to be cut to wound size without unravelling or shredding ADAPTIC Non-Adhering Dressing removes cleanly from the wound, minimising trauma and pain 2,3 ADAPTIC Non-Adhering Dressing is indicated for dry to highly exuding wounds where adherence of dressing and exudate is to be prevented, including: First and second degree burns Abrasions, grafts Venous ulcers Pressure ulcers Nail extractions eczema, staples Surgical incisions Lacerations reconstructive procedures Suture lines 2012 7.6cm x 7.6cm 3 x 3 50 12 (600 eaches) 5 (3000 eaches) 2013 7.6cm x 20.3cm 3 x 8 3x36 6 (648 eaches) 4 (2592 eaches) 2014 7.6cm x 40.6cm 3 x 16 36 6 (216 eaches) 6 (1296 eaches) 2015 7.6cm x 20.3cm 3 x 8 24 6 (144 eaches) 12 (1728 eaches) 2018 7.6cm x 152.4cm 3 x 60 1 ( eaches) 12 (120 eaches) 2019 12.7cm x 22.9cm 5 x 9 12 6 (72 eaches) 14 (08 eaches) 28 Section Product Information References: 1. Hollinworth H and Collier M. Nurses view about pain and trauma at dressing changes: results of a national survey. J Wound Care 2000 : 9 : 369-73 2. EWMA Position Document: Pain at wound dressing changes. European Wound Management Association, 2002 3. Terrill PJ and Varughese G. A comparison of three primary nonadherent dressings applied to hand surgery wounds. J Wound Care 2000 : 9 : 359-63 Section 29

ADAPTIC DIGIT ADAPTIC DIGIT Non-Adhering Digit Dressing ADAPTIC DIGIT Non-Adhering Digit Dressing is made of a unique tacky silicone coated open-knit cellulose fabric with a double-coiled tubular bandage that is specifically designed for dressing fingers and toes ADAPTIC DIGIT is comfortable, convenient to apply and easy to remove for mild to severe digit injuries No applicator or scissors are needed making it easy and simple to use: ADAPTIC DIGIT is conformable and non-bulky, therefore allowing maximum digit flexibility ADAPTIC DIGIT removes cleanly from the wound, minimising trauma and pain 1 ADAPTIC DIGIT Dressing is indicated to manage a range of mild to severe digit injuries. cartons Per CASE ADAPTIC Digit MAD003 Small 2cm Ø 17 (170 eaches) MAD013 Medium 2.4cm Ø 17 (170 eaches) MAD023 Large 2.8cm Ø 17 (170 eaches) MAD042 Extra Large 3cm Ø 17 (170 eaches) ADAPTIC Digit Toe MAD062 2.8cm Ø 17 (170 eaches) Reference: 1. Whittaker S. A dressing for the occasion? A comparative trial of two dressings for digit injuries. Professional Nurse Magazine, 1994 Aug. 729-732 30 Section Product Information Section 31

BIOCLUSIVE BIOCLUSIVE Transparent dressing BIOCLUSIVE Transparent Dressings are made from thin, transparent polyurethane film and can be used on Wound Care and Access Devices. BIOCLUSIVE Dressings may also be used as secondary dressings with PROMOGRAN, PROMOGRAN PRISMA, NU-GEL Hydrogel with Alginate and NU-GEL Wound Dressing for wounds with low levels of exudate. Allows oxygen vapour transfer and helps maintain a moist woundhealing environment 1 Permits continuous observation Works as a physical bacterial/viral barrier and protects site from external contamination 1 helps secure catheters, reducing mechanical irritation Minimises skin irritation1 and helps protect fragile tissue 1 Three-step application, forgiving adhesive for controlled and wastefree application BIOCLUSIVE Select s frame delivery system provides superior application control BIOCLUSIVE and BIOCLUSIVE Select Transparent Dressings should be used under Health Care Professional direction for the following indications; low exuding wounds where observation and protection are desired e.g. General Wound Care, skin biopsies, donor sites, superficial partial thickness burns and surgical incisions. They are also indicated to aid securing of peripheral IVs and Central Venous Catheters. Per CASE BIOCLUSIVE Mini 2460 3.8cm x 3.8cm 1 1/2 x 1 1/2 0 4 (400 eaches) 2461 5.1cm x 7.6cm 2 x 3 0 4 (400 eaches) BIOCLUSIVE 2463.2cm x 12.7cm 4 x 5 50 4 (200 eaches) 2465 12.7cm x 17.8cm 5 x 7 20 5 (0 eaches) 2467.2cm x 25.4cm 4 x 20 6 (120 eaches) 2469 20.3cm x 25.4cm 8 x 8 (80 eaches) BIOCLUSIVE Select 2455 7cm x 6cm 2 3/4 x 2 3/8 50 4 (200 eaches) 2457.2cm x 12.7cm 4 x 5 50 4 (200 eaches) 2474 4.4cm x 7.0cm 1 3/4 x 2 3/4 0 4 (400 eaches) 2475 7.6cm x.2cm 3 x 4 50 4 (200 eaches) Reference: 1. Thomas S (1990) Semipermeable Film Dressings. In: Wound Management and Dressings. London. The Pharmaceutical Press. Pages 25-34 32 Section Product Information Section 33

NU-DERM ALGINATE NU-DERM Alginate WOUND dressing NU-DERM Alginate Wound Dressing is a sterile, non-woven pad consisting of high G (guluronic acid) alginate and carboxymethylcellulose (CMC) fibre. NU-DERM Alginate Wound Dressing is designed to be fast gelling and to allow intact removal. high absorbent capacity1, for fewer dressing changes Quickly forms a hydrophilic gel at the wound surface to help create a moist wound healing environment Conformable when moist; less disruptive to new tissue Maintains tensile strength when wet1, for intact dressing removal and minimising the need for wound irrigation Can be cut or folded to accommodate wound bed NU-DERM Alginate Wound Dressing is indicated for the management of moderate to heavily exuding chronic wounds and to control minor bleeding in superficial acute wounds. Chronic wounds: Pressure ulcers, leg ulcers, venous stasis ulcers, diabetic ulcers and arterial ulcers. Superficial acute wounds: Abrasions, lacerations, donor sites and postoperative wounds. CODE SIZE EACHES PER AWD112 Rope 2.5cm x 30.5cm 1 x 12 5 5 (25 eaches) 6 (150 eaches) AWD202 5cm x 5cm 2 x 2 12 (600 eaches) AWD404 cm x cm 4 x 4 12 (600 eaches) AWD408 cm x 20cm 4 x 8 5 5 (25 eaches) 8 (200 eaches) Reference: 1. Data on file 34 Section Product Information Section 35

NU-DERM HYDROCOLLOID NU-DERM Hydrocolloid Dressing NU-DERM Hydrocolloid Dressing is a sterile hydrocolloid wound dressing designed to maintain a moist wound environment. The NU-DERM Hydrocolloid Wound Dressings consist of a wound contact layer of hydrocolloid and come in a variety of shapes and sizes. The top layer is either a semi-permeable polyurethane film (Border and Thin), or a film-coated polyurethane foam (Standard). The Border product is conformable, has a top layer of low-friction film, and has bevelled edges all around the product - the border itself is a continuation of the skin-friendly hydrocolloid adhesive material The Standard product has a top layer of foam, rounded corners, and is uniform in thickness The semi-transparent Thin product, which is conformable and has a top layer of low-friction film, allows close and easy monitoring of the wound bed without dressing removal helps maintain a moist wound healing environment and encouraging autolytic debridement, thus enabling granulation to proceed under optimum conditions Designed to protect low risk wounds against bacterial contamination* The dressing material interacts with wound exudate to form a soft gel - due to the matrix formulation of the hydrocolloid material, most of the gel is removed together with the dressing, resulting in little or no damage to the newly formed tissue The dressings are waterproof and remain in place during showering NU-DERM Border and NU-DERM Standard are primarily indicated for the management of lightly to moderately exuding pressure sores and leg ulcers NU-DERM Thin is primarily indicated for the management of superficial dry/lightly exuding wounds, post-operative wounds, and superficial wounds and abrasions; however it is also useful on small wounds towards the end of the healing phase 36 Section Product Information NU-DERM Hydrocolloid Border Thin Per CASE HCT1 cm x cm 4 x 4 (0 eaches) NU-DERM Hydrocolloid Standard HCF204 cm x cm 4 x 4 5 (50 eaches) HCF208 20cm x 20cm 8 x 8 5 4 (20 eaches) NU-DERM Hydrocolloid Border HCB2 5cm x 5cm 20 5 (0 eaches) HCB204 cm x cm 4 x 4 16 (160 eaches) HCB6 15cm x 15cm 6 x 6 5 4 (20 eaches) HCB8 20cm x 20cm 8 x 8 5 4 (20 eaches) NU-DERM Hydrocolloid Border Elbow and Heel HCH207 8cm x 12cm 6 (60 eaches) NU-DERM Hydrocolloid Border Sacrum HCS0 15cm x 18cm 6 x 7 5 4 (20 eaches) * Consult a physician prior to using NU-DERM Hydrocolloid Dressings on lesions caused by tuberculosis, syphilis or deep fungal infections, cancer and wounds at high risk of infection Section 37

NU-GEL HYDROGEL WITH ALGINATE NU-GEL Hydrogel with Alginate NU-GEL Hydrogel is a transparent hydro-active amorphous gel containing sodium alginate that gently and effectively rehydrates necrotic tissue and fibrinous slough, and is designed to create an ideal moist wound healing environment for granulating and epithelising wounds. 1 NU-GEL Hydrogel gently and effectively provides rehydration of the wound for autolytic debridement, significantly decreasing the amount of necrotic tissue and slough 2 The alginate increases the absorptive capacity of NU-GEL Hydrogel and improves the ability to control wound exudate 1 for longer wear time 1 NU-GEL Hydrogel can be applied to the wound with a simple onehanded technique NU-GEL Hydrogel is indicated for debridement and desloughing of wounds together with the management of chronic wounds throughout all stages of the healing process. Precaution NU-GEL Hydrogel contains propylene glycol which might cause irritation or sensitisation in a small number of patients. If such reactions are noted, use of NU-GEL Hydrogel should be discontinued. If wound infection is present, appropriate antimicrobial therapy should be initiated - the use of NU-GEL Hydrogel may be continued under medical supervision. CODE SIZE EACHES PER MNG415 15g 4 (40 eaches) 8 (320 eaches) MNG425 25g 6 4 (24 eaches) 8 (192 eaches) References: 1. A study of two hydrogels used in the management of pressure sores, T. Young et al. Published in the Proceedings of the 6th European Conference on Advances in Wound Management. Conference held in Amsterdam, 1-4th October 1996 2. Autolytic debridement of chronic wounds using a Hydrogel (NU- GEL ). Vanscheidt V, Hasse G & Wunsch N. Vasomed: 9, Jan. 1997; 26-34 38 Section Product Information Section 39

NU-GEL WOUND DRESSING NU-GEL Wound Dressing NU-GEL Wound Dressing is a hydrogel dressing consisting of polyvinyl pyrrolidone in water. The gel is supported by a fusible fibre scrim and protected on both sides by polyethylene film. helps maintain moist wound environment which encourages autolytic debridement Designed to protect against dehydration and provide a physical barrier against bacterial contamination Naturally cooling & soothing to help reduce patient pain and discomfort Absorbs exudate which helps reduce pooling of fluid remains intact; does not break down Translucent - allows monitoring of wound without disturbing the dressing Versatile - can be cut to size of the wound CODE SIZE EACHES PER Per case NU-GEL Wound Dressing is indicated for first and second degree burns, partial thickness wounds, decubitus ulcers, donor sites, severe sunburn, superficial injuries or secreting dermal lesions, superficial lacerations, cuts and abrasions, incisions, skin reactions to oncology procedures, dermabrasions and other dermatologic procedures such as facelifts and other plastic surgery procedures. 2497 9.5cm x 9.5cm 3X x 3X 5 (50 eaches) 2498 15.2cm x 20.3cm 6 x 8 5 6 (30 eaches) Reference: 1. Multicentre evaluation of NU-GEL dressing in full-thickness chronic wounds of the lower extremities Morton I. Altman and Gerit TI. Mulder, California College of Podiatric Medicine, San Francisco, California, USA; and Wound Healing Institute, Aurora, Colorado, USA 40 Section Product Information Section 41

DYNA-FLEX DYNA-FLEX Multi-Layer Compression System DYNA-FLEX Multi-Layer Compression System provides proven sustained compression 1 to reduce the effects of venous insufficiency. Available in selected markets only. DYNA-FLEX Multi-Layer Compression System provides sustained compression for up to seven days at both the ankle and below the knee, when used according to package insert directions. Each component has been carefully engineered to provide an effective solution ideal for use in all settings. First layer: Made of cool, breathable cotton and foam helps protect the patient from pressure points Absorbs exudate reduces slippage Comfortable for the patient Provides excellent wicking Foam backing provides strength for added stretching and conformability Second layer: Compression bandage uses an innovative, patented visual cue to aid proper application The bandage is printed with a rectangular pattern that turns to a square when correct level of stretch is achieved This assists in achieving reproducible pressures from one practitioner to another Third layer: Cohesive compression bandage helps prevents slippage and increases compliance. 7025 1 8 (8 eaches) DYNA-FLEX Multi-Layer Compression System is suitable for the management of venous leg ulcers and related conditions. The compression system may be used on patients with an ankle circumference 18 cm or larger (padded). Precaution This product contains natural rubber latex which may cause allergic reactions. 42 Section Product Information Reference: 1. Blair S, Wright D, Backhouse C, Riddle E, McCollum C. Sustained compression and healing of chronic venous ulcers. Br Med J. 1988;297:1159-1161 Section 43

ALGOSTERIL ALGINATE ALGOSTERIL Calcium Alginate dressing ALGOSTERIL is a natural, pure, non-woven dressing made of calcium alginate fibres, that promotes granulation. 1,2 Available in selected markets only. When in contact with blood ALGOSTERIL accelerates platelet aggregation, enhancing the haemostatic process 1 Simultaneously, calcium ions stimulate macrophages and other important cells of the healing process (macrophages eat necrotic debris, fight micro organisms and liberate growth factors) 2 ALGOSTERIL acts as a wound filler While absorbing exudate, ALGOSTERIL fibres gel, helping to create a moist wound healing environment ALGOSTERIL s fibres have an outstanding absorption and retention capacity 3 ALGOSTERIL also absorbs and retains bacteria in its interfibrilar space, thus reducing the potential for infection 2,3,4 Designed to facilitate painless and easy removal1,4, leaving minimal residue in the wound 1 Safety: 0% plant origin, hypo-allergenic2,3 ALGOSTERIL is indicated for moderately to heavily exuding wounds, such as chronic wounds (leg ulcers, pressure sores, diabetic foot), deep wounds, bleeding wounds, donor sites and infected and sloughy wounds. Box Per CASE 3490 5cm x 5cm 12 (120 eaches) 3492 9.5cm x 9.5cm (0 eaches) 3493 cm x 20cm 6 (60 eaches) 3495 Rope 2cm x 30cm 6 6 (36 eaches) Registered Trademark of Les Laboratoires Brothier References: 1. ALGOSTERIL vs. Paraffin gauze in the treatment of skin graft donor sites in children scalps. XVth Congress of the French Society of Studies and Treatment of Burn Patients, Bordeaux, June 1996 2. ALGOSTERIL vs. Povidone Iodine dressing in the treatment of infected wounds. IXth European Congress of Infectious Surgery, Paris, June 1996 3. ALGOSTERIL dressing vs. Dextanomere in the treatment of Decubitus Ulcers at 20 French Centres 8th Annual Symposium on the Treatment of the Wound, San Diego, USA, May 1995 4. ALGOSTERIL in the treatment of infected wounds. 8th Annual Symposium on Advanced Wound Care & 5th Annual Medical Forum on Wound Repair, San Diego, USA, April 3, May 4, 1995 44 Section Product Information Section 45

TRIONIC ALGINATE TRIONIC Alginate dressing with calcium, zinc & manganese ions TRIONIC is a cell-active alginate made from brown algae and chlorophyll as well as calcium, zinc and manganese ions, that helps promote tissue regeneration and wound healing. 1-5 Available in selected markets only. TRIONIC absorbs exudate and traps necrotic debris and bacteria 5-7 in its interfibrilar space, thus promoting wound cleansing and granulation The zinc, manganese and calcium ions contained in TRIONIC help stimulate cell activities and foster tissue regeneration (Zinc and Manganese are enzyme cofactors highly important in tissue regeneration, as any deficiency in Zinc and Manganese is associated with healing delays) 4 When in contact with sodium-containing fluids such as blood, wound exudate, Ringer s solution and saline solution, TRIONIC forms a structurally sound gel, which helps create a moist wound healing environment TRIONIC is of a 0% plant origin and hypo-allergenic 1,5,6 TRIONIC is designed to facilitate minimal pain and easy removal 1,4, with reduced damage to the newly formed tissue and leaving minimal residue in the wound 1 Box Per CASE TRI300 5cm x 5cm 12 (120 eaches) TRI301 9.5cm x 9.5cm (0 eaches) TRI302 cm x 20cm 6 (60 eaches) TRI303 Rope 2cm x 30cm 6 6 (36 eaches) For use on moderate to heavily exuding wounds, such as pressure ulcers, leg ulcers, diabetic foot ulcers, post operative cutaneous wound dehiscence, amputation stumps, abscesses, donor sites and burns. Registered Trademark of Les Laboratoires Brothier References: 1. Ziegler U.E. et al. The treatment of chronic wounds with a new calcium-zinc-manganese alginate dressing. Fortschritte der Medizin 121. Jg. Originalien Nr.1/2003, S. 19-26 2. Tarin Saez J.J. et al. Effectiveness of bioactive dressing with ionic charge in the reduction of healing time in chronic wounds. Metas de Enferm 9(1): 58-64, February 2006 3. Castellarnau C. et al. The activating function of bioactive dressing with ionic charge on human fibroblasts. Metas de Enferm 8(7): 50-54, September 2005 4. ALGOSTERIL vs. Paraffin gauze in the treatment of skin graft donor sites in children scalps. XVth Congress of the French Society of Studies and Treatment of Burn Patients, Bordeaux, June 1996 5. ALGOSTERIL vs. Povidone Iodine dressing in the treatment of infected wounds. IXth European Congress of Infectious Surgery, Paris, June 1996 6. ALGOSTERIL dressing vs. Dextanomere in the treatment of Decubitus Ulcers at 20 French Centres. 8th Annual Symposium on the Treatment of the Wound, San Diego, USA, May 1995 7. ALGOSTERIL in the treatment of infected wounds. 8th Annual Symposium on Advanced Wound Care & 5th Annual Medical Forum on Wound Repair, San Diego, USA, April 3, May 4, 1995 46 Section Product Information Section 47

N-A & N-A ULTRA N-A and N-A ULTRA Dressings N-A Dressing is a primary wound contact layer consisting of a knitted viscose rayon sheet. N-A ULTRA Dressing is a primary wound contact layer consisting of a knitted viscose rayon sheet with a silicone coating. N-A and N-A ULTRA Dressings allow free passage of exudate from the wound surface through to any secondary absorbent layer and simple atraumatic removal. 1 N-A and N-A ULTRA Dressings are wound contact layers for use on leg ulcers, pressure sores, burns and other granulating wounds. N-A P570 9.5cm x 9.5cm 40 18 (720 eaches) 2 (1440 eaches) P572 19cm x 9.5cm 25 4 (0 eaches) 8 (800 eaches) P579 9.5cm x 9.5cm 40 1 (40 eaches) 47 (1880 eaches) N-A Ultra MNA095 9.5cm x 9.5cm 40 1 (40 eaches) 47 (1880 eaches) MNA190 19cm x 9.5cm 25 4 (0 eaches) 8 (800 eaches) MNA011 19cm x 19cm 5 5 (25 eaches) 5 (125 eaches) Reference: 1. Burton, F. An evaluation of non-adherent wound-contact layers for acute traumatic and surgical wounds, J. of Wound Care, No 9, Oct. 2004 48 Section Product Information Section 49

SILVERCEL NON-ADHERENT Dressing CAD7050 5cm x 5cm (500 eaches) CAD7011 11cm x 11cm 12 (600 eaches) CAD7020 cm x 20cm 5 5 (25 eaches) 8 (200 eaches) CAD7230 2.5cm x 30.5cm 5 5 (25 eaches) 6 (150 eaches) PROMOGRAN Protease Modulating Matrix M770285 28cm 2 5 8 (40 eaches) 18 (720 eaches) M771235 123cm 2 5 8 (40 eaches) 6 (240 eaches) M772028 28cm 2 4 (40 eaches) 18 (720 eaches) M772123 123cm 2 4 (40 eaches) 6 (240 eaches) ACTISORB Antimicrobial dressings MAS065 6.5cm x 9.5cm 28 (1400 eaches) MAS5.5cm x.5cm 9 (450 eaches) PROMOGRAN PRISMA Matrix Wound Dressing PS2028 28cm 2 4 (40 eaches) 18 (720 eaches) PS2123 123cm 2 4 (40 eaches) 6 (240 eaches) MAS190 19cm x.5cm 12 (600 eaches) INADINE PVP-I Non-Adherent Dressing P01481 5cm x 5cm 25 (250 eaches) 4 (00 eaches) P01512 9.5cm x 9.5cm 25 (250 eaches) 2 (500 eaches) P01491 9.5cm x 9.5cm (0 eaches) 4 (400 eaches) FIBRACOL Plus Collagen Alginate Dressing 2981 2 x 2 12 6 (72 eaches) 15 (80 eaches) 2982 4 x 4 12 6 (72 eaches) 5 (360 eaches) 2983 4 x 8 6 6 (36 eaches) 6 (216 eaches) 2984 40cm (15 X ) 6 6 (36 eaches) 3 (8 eaches) SILVERCEL Antimicrobial Dressing CAD050 5cm x 5cm 12 (600 eaches) CAD011 11cm x 11cm 12 (600 eaches) CAD020 cm x 20cm 5 5 (25 eaches) 8 (200 eaches) CAD230 2.5cm x 30.5cm 5 5 (25 eaches) 6 (150 eaches) 50 Section Sizes Codes and Ordering Information Section 51

TIELLE Hydropolymer dressings TIELLE LITE MTL300 7cm x 9cm 9 (450 eaches) MTL301 11cm x 11cm 4 (200 eaches) MTL308 8cm x 15cm 5 (250 eaches) MTL309 8cm x 20cm 5 (250 eaches) TIELLE MTL0 7cm x 9cm 9 (450 eaches) MTL1 11cm x 11cm 12 (600 eaches) MTL2 15cm x 20cm 5 5 (25 eaches) 5 (125 eaches) MTL3 18cm x 18cm 5 5 (25 eaches) 3 (75 eaches) MTL5 15cm x 15cm 2 (0 eaches) MTL1 cm x cm 20 5 (0 eaches) 4 (400 eaches) TIELLE SACRUM MTL4 18cm x 18cm 5 5 (25 eaches) 3 (75 eaches) TIELLE PACKING MT2450 9.5cm x 9.5cm 12 (600 eaches) TIELLE PLUS MTP501 11cm x 11cm 4 (200 eaches) MTP502 15cm x 20cm 5 5 (25 eaches) 4 (0 eaches) MTP505 15cm x 15cm 2 (0 eaches) TIELLE PLUS HEEL MTP508 20cm x 26.5cm 5 5 (25 eaches) 4 (0 eaches) TIELLE PLUS SACRUM MTP506 15cm x 15cm 2 (0 eaches) TIELLE MAX MTP701 11cm x 11cm 8 (400 eaches) MTP702 15cm x 20cm 5 5 (25 eaches) 5 (125 eaches) MTP705 15cm x 15cm 4 (200 eaches) TIELLE XTRA MTP301 11cm x 11cm 8 (400 eaches) MTP302 15cm x 20cm 5 5 (25 eaches) 5 (125 eaches) MTP305 15cm x 15cm 4 (200 eaches) ADAPTIC Non-Adhering dressing 2012 7.6cm x 7.6cm 3 x 3 50 12 (600 eaches) 5 (3000 eaches) 2013 7.6cm x 20.3cm 3 x 8 3x36 6 (648 eaches) 4 (2592 eaches) 2014 7.6cm x 40.6cm 3 x 16 36 6 (216 eaches) 6 (1296 eaches) 2015 7.6cm x 20.3cm 3 x 8 24 6 (144 eaches) 12 (1728 eaches) 2018 7.6cm x 152.4cm 3 x 60 1 ( eaches) 12 (120 eaches) 2019 12.7cm x 22.9cm 5 x 9 12 6 (72 eaches) 14 (08 eaches) ADAPTIC DIGIT Non-Adhering Digit Dressing ADAPTIC Digit cartons Per CASE MAD003 Small 2cm Ø 17 (170 eaches) MAD013 Medium 2.4cm Ø 17 (170 eaches) MAD023 Large 2.8cm Ø 17 (170 eaches) MAD042 Extra Large 3cm Ø 17 (170 eaches) ADAPTIC Digit Toe MAD062 2.8cm Ø 17 (170 eaches) BIOCLUSIVE Transparent dressing BIOCLUSIVE Mini Per CASE 2460 3.8cm x 3.8cm 1 1/2 x 1 1/2 0 4 (400 eaches) 2461 5.1cm x 7.6cm 2 x 3 0 4 (400 eaches) BIOCLUSIVE 2463.2cm x 12.7cm 4 x 5 50 4 (200 eaches) 2465 12.7cm x 17.8cm 5 x 7 20 5 (0 eaches) 2467.2cm x 25.4cm 4 x 20 6 (120 eaches) 2469 20.3cm x 25.4cm 8 x 8 (80 eaches) BIOCLUSIVE Select 2455 7cm x 6cm 2 3/4 x 2 3/8 50 4 (200 eaches) 2457.2cm x 12.7cm 4 x 5 50 4 (200 eaches) 2474 4.4cm x 7.0cm 1 3/4 x 2 3/4 0 4 (400 eaches) ADAPTIC TOUCH Non-Adhering Silicone Dressing TCH501 5cm x 7.6cm 15 (750 eaches) TCH502 7.6cm x 11cm 12 (600 eaches) TCH503 12.7cm x 15cm 5 (250 eaches) TCH504 20cm x 32cm 5 1 (5 eaches) (50 eaches) 2475 7.6cm x.2cm 3 x 4 50 4 (200 eaches) NU-DERM Alginate dressing CODE SIZE EACHES PER AWD112 Rope 2.5cm x 30.5cm 1 x 12 5 5 (25 eaches) 6 (150 eaches) AWD202 5cm x 5cm 2 x 2 12 (600 eaches) AWD404 cm x cm 4 x 4 12 (600 eaches) AWD408 cm x 20cm 4 x 8 5 5 (25 eaches) 8 (200 eaches) 52 Section Sizes Codes and Ordering Information Section 53

NU-DERM Hydrocolloid Dressing ALGOSTERIL Calcium Alginate dressing Per CASE Box Per CASE NU-DERM Hydrocolloid Border Thin HCT1 cm x cm 4 x 4 (0 eaches) NU-DERM Hydrocolloid Standard HCF204 cm x cm 4 x 4 5 (50 eaches) 3490 5cm x 5cm 12 (120 eaches) 3492 9.5cm x 9.5cm (0 eaches) 3493 cm x 20cm 6 (60 eaches) 3495 Rope 2cm x 30cm 6 6 (36 eaches) HCF208 20cm x 20cm 8 x 8 5 4 (20 eaches) NU-DERM Hydrocolloid Border HCB2 5cm x 5cm 20 5 (0 eaches) HCB204 cm x cm 4 x 4 16 (160 eaches) HCB6 15cm x 15cm 6 x 6 5 4 (20 eaches) HCB8 20cm x 20cm 8 x 8 5 4 (20 eaches) NU-DERM Hydrocolloid Border Elbow and Heel HCH207 8cm x 12cm 6 (60 eaches) NU-DERM Hydrocolloid Border Sacrum HCS0 15cm x 18cm 6 x 7 5 4 (20 eaches) TRIONIC Alginate dressing with calcium, zinc and manganese ions Box Per CASE TRI300 5cm x 5cm 12 (120 eaches) TRI301 9.5cm x 9.5cm (0 eaches) TRI302 cm x 20cm 6 (60 eaches) TRI303 Rope 2cm x 30cm 6 6 (36 eaches) NU-GEL Hydrogel with Alginate CODE SIZE EACHES PER MNG415 15g 4 (40 eaches) 8 (320 eaches) MNG425 25g 6 4 (24 eaches) 8 (192 eaches) N-A and N-A ULTRA Dressings N-A P570 9.5cm x 9.5cm 40 18 (720 eaches) 2 (1440 eaches) P572 19cm x 9.5cm 25 4 (0 eaches) 8 (800 eaches) P579 9.5cm x 9.5cm 40 1 (40 eaches) 47 (1880 eaches) N-A Ultra MNA095 9.5cm x 9.5cm 40 1 (40 eaches) 47 (1880 eaches) NU-GEL Wound Dressing MNA190 19cm x 9.5cm 25 4 (0 eaches) 8 (800 eaches) CODE SIZE EACHES PER Per case MNA011 19cm x 19cm 5 5 (25 eaches) 5 (125 eaches) 2497 9.5cm x 9.5cm 3X x 3X 5 (50 eaches) 2498 15.2cm x 20.3cm 6 x 8 5 6 (30 eaches) DYNA-FLEX Multi-Layer Compression System 7025 1 8 (8 eaches) 54 Section Sizes Codes and Ordering Information Section 55

SYS/GLO/370/0211 Systagenix Wound Management 2011. Brands marked with or are trademarks of Systagenix. All other products referenced herein are acknowledged to be trademarks of their respective owners. www.systagenix.com