Czech Biotech. Great past, present, promising future Overall description Association CzechBio CzechBio members



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Czech Biotech Great past, present, promising future Overall description Association CzechBio CzechBio members

Great past Czechoslovakia used to be extremely strong in traditional biotech Biotransformations: Crop and animal breeding Fermentation industry Famous brewery tradion Production of wine, ethanol, baker s yeast Aminoacid production, cyclosporine A, ergot alcaloids, vitamins, food additives Among pioneers of antibiotics production penicillin (October 1949) World famous school of continuous culture technology (at Institute of Microbiology of Czech Academy of Science)

Current shape of biotech in CZ Somewhat behind in cutting-edge biological research Limited cooperation between academia and private companies Limited interest of the venture capital Advance biotech intellectual property is limited So far Czech biotech companies didn t succeed in delivering original biotech product in field of human medicine to the market

Biotech industry in CZ All together more than 40 companies located mostly in the region of Central Bohemia and South Moravia Directly employed: 1 800 2 200 employees Total yearly turnover: 160 200 mil EUR Average year growth: 12 16 % 30% 9% 38% Výroba Služby 23% Výzkum a vývoj Ostatní

Promising future Government starts to recognize the problem: Advanced biotechnology and molecular biology among strategic long-term research orientations More funds to competent teams and individuals Good culture, education, enough PhDs, qualified manpower National applied research support scheme Incentives for Academia collaboration with industry ERDF funds (4,5 bil. Euro ), for OP R&D fair portion going into biotech Number of projects BIOCEV, CEITEC, NBBC, CzechBio

Promising future 2001 : Center of Biological Technologies technological incubator incl. green tech in South Bohemia 2006: Water Treatment Alliance - development high tech tools and innovations (incl. biotech) in water treatment 2007: CEITEC Central European Institute of Technology (South Moravia) BIOCEV Biotech & Biomed Research Center of AS CR promotion of cutting edge biotech and biomed R&D in CZ, 2008 (January) Institute of Biotechnology established by AS CR 2008 (December) CzechBio association established

CzechBio z. s. p. o. A rapidly growing association of biotech companies, renowned research institutions and Universities operating in CZ Aiming at developing Czech biotech industry Represents the famous traditional Czech biotech R&D Founding members: Current members: 20 private biotech companies 29private biotech companies 3 R&D institutions + 1 university

CzechBio membership base 7 6 4 5 2 13 12 4 6 Eco/Envir Pharm/Med Prod Diag/Assay Prod Diag/Testing Serv Mol Biol Other 9 R&D Services Production Other

Selected biotech companies - Prague Immunotech (Beckman Coulter) immunodiagnostics BIOPREPARÁTY biological plant protection GeneAge Technologies expression profiling Genomac International sequencing/genotyping LentiKat waste water treatment R&D Top-Bio molecular biol. kits producer SME (<5)

Sel. biotech companies Central Bohemia Apronex SME, recombinant proteins (4 p) Baxter Czech flu vaccine production site Biologicals SME, forensics, HCV-Y-Screen Dyntec veterinary products EXBIO Mab and reagent producer Lonza Biotec fermentation plant and R&D FDA-registered pharma enzymes Proteix SME, recombinant proteins (3 p) recoli SME, recombinant proteins VIDIA SME, clinical diagnostic kits BioTest drug and biologicals testing,r&d

Sel. biotech companies South Moravia BioVendor SME, recombinant proteins, diagnostics Bioveta veterinary vaccines R&D and production Enantis SME, recombinant dehalogenases contract research in protein engineering EPS SME, bioremediation, biogas Moravian-Biotechnology SME, custom antibody services TEST-LINE SME, human and veterinary diagnostics

Sel. biotech companies remaining regions GENERI BIOTECH SME, oligonucleotides, DNA genotyping services Contipro Group world leader in hyaluronic acid GMP recombinant defensins, wound healing R&D Protean SME, DNA diagnostics, recombinant proteins ENVISAN-GEM bioremediation GEN-TREND SME, diagnostics and proteins AgroBio agrochemicals and agrobiologicals Biocel pulp industry fodder yeast producer IVAX-Teva Pharmaceuticals, generics Ascoprot Biotech SME (5 p.) rec. proteins OlChemIm SME, phytohormones, antibodies (5 p)

Basic facts about largest member companies BTÚ AV ČR, v.v.i. - 46 employees founded1.1.2008 project BIOCEV LONZA Biotec, s.r.o, Kouřim Employees: 380 Bulk custom GMP biomanufacturing Sevapharma a.s. Employees 100 vaccines, imunomodulators, alergens Ann. Turnover : CZK1,5 bilion EUR 60 milion Turnover: CZK150 milion EUR 6,5 milion Biopharm a.s. Employees: 90 Veterinary vaccines and drugs Turnover: CZK 80 milion EUR 3,3 milion BioVendor Laboratorní medicína a.s. Employees: 150 Recombinant proteins and ELISA kits Turnover: CZK 1 bilion EUR 40 milion Bioveta a.s. Employees: 330 Turnover: CZK 500 milion EUR 20 milion Veterinary vaccines and immunopreparations

CzechBio offers: Guidance through the Czech biotech sector Partnership with academic institutions and biotech companies offering wide range of biotech services Comprehensive database of biotech companies to be approached Partnership in R&D activities Representation in number of expos & trade fairs Active participation on regular expert seminars and mingling sessions Use of our laboratory

Contact: Web: www.czechbio.org Address: Nad Safinou II/366, 252 42 Jesenice u Prahy Tel: + 420 733 784 755 Contact person: Marek Polach marek.polach@czechbio.org

Thank you for your attention!