Contemporary insights into cancer. Risks, perspectives, expectations. 13.00-14.00 Lunch 14.00-15.30 Mechanisms of tumor growth and differentiation

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Contemporary insights into cancer. Risks, perspectives, expectations Saturday, Feb 16 th 13.00-14.00 Lunch 14.00-15.30 Mechanisms of tumor growth and differentiation Prof. Alicja Józkowicz 14.10-14.40 Role of micrornas in tumor growth and differentiation Agata Szade 14.40-14.55 Role of heme oxygenase-1 in squamous cell carcinoma Maciej Ciesla 14.55-15.10 Novel therapies of rhabdomyosarcoma Jacek Stępniewski 15.10-15.25 Teratoma formation as the model for pluripotency of stem cells 15.25-16.00 Coffee break and poster viewing 16.00-18.45 Angiogenesis and anti-angiogenic therapies Dr Agnieszka Łoboda 16.00-16.30 Hypoxia-driven tumor vascularisation Dr Agnieszka Jaźwa Regulatable vectors for pro-and anti-angiogenic therapies Prof. Józef Dulak micrornas in tumor angiogensis: tools and targets Anna Grochot-Przeczek 17.30-17.45 Proangiogenic progenitor cells Krzysztof Szade 17.45-18.00 In vivo imaging of angiogenesis and tumor growth: novel models Witold Nowak 18.00-18.15 New approaches to treatment of leukemias Urszula Florczyk 18.15-18.30 Role of Nrf2 in tumor angiogenesis Magdalena Kozakowska 18.30-18.45 Acellular proangiogenic therapies 19.00-21.30 Welcome party and reminiscences

Sunday, Feb 17 th 14.00-16.00 Targeted therapies 14.30-14.55 14.55-15.15 15.15-15.30 Inaugural lecture: Prof. Tomasz Grodzicki Dark side of the moon - consequences of curing cancer Prof. Hanna Rokita Anti-GD2 ganglioside strategy in treatment of neuroblastoma Dr Irena Horwacik Application of molecular mimicry to target GD2 ganglioside Durbas Małgorzata A role of aurora A kinase and its substrates in 14G2a monoclonal antibody toxicity against human neuroblastoma Prof. Grzegorz Bartosz Multidrug transporters and their role in the failure of cancer chemotherapy 16.30-18.30 Anti-cancer molecular biology strategies 16.30-16.55 16.55-17.20 17.20-17.45 17.45-18.05 18.05-18.30 Dr Dominika Nowis Influence of statins on glucose uptake by human cells Prof. Claudine Kieda Angiogenesis normalization strategies: molecular mechanism in tumor therapy Prof. Joanna Bereta Genetically-modified Salmonella - a new option in cancer therapy? Maria Czarnek Role of ADAM17 in a murine model of colon carcinoma Dr Monika Bzowska 20.00-21.30 Poster session I Tumor-targeting with monoclonal antibodies

Monday, Feb 18 th 8.30-11.30 First premedical aid training (in Polish) Marcin Zawrotniak 11.30-13.00 Poster session II 14.00-16.00 Radiotherapy of cancer 14.30-15.00 15.00-15.30 Prof. Howard Halpern Application of EPR O 2 Imaging to Radiation Biology and Therapy Prof. Bożena Romanowska-Dixon A new treatment modality of intraocular neoplasm - proton radiotherapy in Kraków Prof. Paweł Olko New opportunities for tumor therapy using proton beam Dr Martyna Elas DNA damage, protein expression and migration of melanoma cells irradiated with proton beam 16.30-18.30 Phototherapy of cancer 17.30-17.50 17.50-18.10 18.10-18.30 Dr Janusz Dąbrowski "Luz11 - a novel photosensitizer for photodynamic therapy on its way from synthesis to clinical trials Martyna Krzykawska F 2 Bmet-PDT effects on vasculature Dr Jolanta Saczko Photodynamic therapy and its modification in cancer cells Monika Jakubowska Double-faced roles of nitric oxide in photodynamic therapy of cancer: our friend or enemy Anita Burkat-Dulak, Justyna Morawska-Płoskonka Delivering innovation in life science branch 20.00-22.00 Student s Science Club

Tuesday, Feb 19 th 14.00-16.00 Immunotherapy of cancer 14.30-15.00 15.00-15.30 Prof. Chantal Pichon RNA-based vaccines Prof. Richard Daniellou "Immunostimulating glycans in cancer Dr Mateusz Kwitniewski DNA methylation and cancer immunotherapy Aleksandra Pęcak Aptamer based approach to target p53-mdm2 interaction in cancer 16.30-18.30 Novel ideas of anti-cancer therapy 17.00-17.40 17.40-17.55 17.55-18.15 Prof. Andrzej Mackiewicz Immunotargeting human melanoma stem cells with Hyper-IL-6 gene modified whole cell vaccine Łukasz Kalinowski, Dr Jerzy Pieczykolan From scientific concept to preclinical evaluation - 3CLA - targeted anticancer therapy Justyna Supel Malopolska Centre of Biotechnology Dr Tomasz Rzymski 19.00-21.00 Conference dinner Perspectives on Development of Novel Classes of Cyclin Dependent Kinase Inhibitors as Anticancer Drugs

Wednesday, Feb 20 th 8.30-12.30 Skiing competition 14.00-16.00 Novel ideas of anti-cancer therapy 14.00-15.00 15.00-15.15 15.15-15.45 Maja Swoboda, Dr Arkadiusz Miciałkiewicz NEXT GENeration SCIENCE - from the sequence to the change. The story how Life Technologies is improving genome research providing tools for genetic engineering. The easy way to advanced regenerative medicine Prof. Alicja Ratuszna A new perspective for the education and science in the modern labs in Silesian Center of Education and Interdisciplinary Research Michał Sarna Nanomechanical analysis of melanoma cells 16:00-16.30 Coffee break and poster viewing 16.30-18.30 Carcinogenesis and tumor development 17.30-18.00 18.00-18.30 Prof. Tadeusz Sarna Are Transition Metal the Missing Risk Factors for Cutaneous Malignant Melanoma? Prof. Ewa Sikora Therapy induced senescence - hope or hype? Dr Maja Grabacka Targeting tumor cell metabolism as an alternative therapeutic perspective" Dr Agnieszka Wolnicka-Głubisz UV-induced melanoma in HGF/SF transgenic mouse 20.00-21.30 Debate: Introducing new therapies into clinic