Dutch Techcentre for Life Sciences



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Dutch Techcentre for Life Sciences next generation life science technology research infrastructure : cross-sector technology initiative Nieuwegein, 19 december 2011 Ruben Kok, Barend Mons, Jaap Heringa, Marcel Reinders; bioinformatics, NBIC Roel van Driel; systems biology, NCSB Thomas Hankemeijer, Merlijn van Rijswijk; metabolomics, NMC Albert Heck, Werner Most; proteomics, NPC Edwin Cuppen, Terry Vrijenhoek; genome diagnostics, CGD Dorus Gadella, Judith Klumperman, light microscopy, NL BioImaging AM

established as an integrated and cross-sector technology research infrastructure From fragmented technology activities towards an integrated cross-sector infrastructure

VISION Dutch Techcentre for Life sciences: next generation LS technology research infrastructure Framework of key tech expert centres genomics (NGS) proteomics metabolomics bioimaging bioinformatics, systems biology & e-science

VISION offers a big technology research infrastructure to enable LS-based topsectors Quality, tuning and access cutting-edge technology research cross-technology data integration expertise & infrastructures support & training single framework cross-sector tuning international link and impact public-private partnerships

VISION Technology research infrastructure to enable LS-based topsectors Access to infrastructures & expertise research support hotels & services in house & global technologies experimental technologies & data aspects education of specialists, training of users access to industry; SME-programme tech transfer to commercial providers part of international facilities (e.g. ESFRI)

and DBH as linking pin to European infrastructures ESFRI ELIXIR

DISC ELIXIR: broad founding alliance LS data infrastructure Compute and storage infrastructure Tools infrastructure Expertise infrastructure Training infrastructure CGD

Essential for LSH and other Topsectors Topsectoren LS&H Agrofood Tuinbouw en uitgangsmaterialen Chemie Hightech materials LS&H roadmaps Molecular diagnostics. Imaging and Image guided therapy Regenerative Medicine Pharmacotherapy One Health Specialized Nutrition, Health and Disease

industry proposition Technology users Existing industry collaboration over 70 companies across all topsectors various ways of involvement Industry Platform joint research projects research services (short-term) training & kenniswerken from 2012 new collaboration strategies and targets will be defined in cooperation with industry Service Providers Technology developers

VISION funding Research NWO/ZonMW/STW FP8, IMI, FET flagship projects academia: van basic funding industry in cash/kind Hotels & services facility grants (roadmap?), NWO-groot, academia: via basic funding >50%: backpack budget in user projects Education & training academia: via basis funding miscellaneous grants

VISION annual funding ambitions Total NL 35% EU 15% Acad. 35% 40 % 24M 8 5 8 3 Ind. 15% 40% 24M 10 3 8 3 5% 3 M 1 0.5 1 0.5 10% 6 M 1.5 0.5 2 2 5% 3 M 0.5 2 0.5

Dutch Techcentre for Life Sciences next generation life science technology research infrastructure

Companies already involved in centres Abbott Agilent Technologies Arcarios Artemis Pharmaceuticals Arthrogen BaseClear BIOBASE GmbH Bioceros Bruker Carls Zeiss Cellzome AG CiberNed CLC bio Convey Computers Crosslinks Dalicon BV Danone Darwin Digits DSM decode Genetics Eli Lilly Epigeomics AG FEI Electron Optics Friensland Campina Galapagos GeneAlice Genome Diagnostics Genmab Harbour Antibodies Heineken Hybrigenics IBM Jansen Pharmaceutica Johnson and Johnson Keygene Merus B.V. Monsanto Nestlé NIZO Novartis Open Analytics Organon/Merck PamGene B.V. Perch Pfizer Philips Pluriomics Profibrix Purac Roche RijkZwaan Breeding Source BioScience Spark-Holland S&T Bioinformatics Thermo Scientific UbiQ Unilever Veridex LLC Waters XomicX