THE LIFE SCIENCE DASHBOARD



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DASHBOARD Cell Culture Dashboard Sample Data 2005-2006 Percepta Associates, Inc. SERIESTWO DEC 08 760 822 2638 www.perceptaassociates.com 0

The Life Science Dashboards from Percepta Associates, Inc. Copyright 2008 by Percepta Associates, Inc., 7040 Avenida Encinas, Suite 104-365, Carlsbad CA 92011. All rights reserved. This report may not be reproduced by any means in whole or in part without written permission from Percepta Associates, Inc. Reproduction and redistribution is strictly forbidden by United States and international law. Copies of this report may be ordered from Percepta Associates. To place an order, call 760-597-9236 or visit the publications section of our webpage at http://www.perceptaassociates.com/publications/. Notice: The information, data and estimates in this report have been obtained from sources believed to be reliable. Every reasonable effort has been made to verify their accuracy. Information contained in this report is very time-sensitive. Please note the publication date. While all reasonable steps have been taken to ensure the accuracy of the information presented, Percepta Associates cannot accept responsibility for inadvertent errors or omissions. Percepta Associates also takes no responsibility for any incorrect information supplied to us by survey participants. The market information contained herein is based on survey responses and information obtained from the public domain and therefore is subject to interpretation. 760 597 9236 www.perceptaassociates.com 1

The Life Science Dashboards from Percepta Associates, Inc. Recognizing that professionals in research supply companies need timely, relevant and practical life science market intelligence to form a fact-based foundation for decision making, Percepta Associates developed The Life Science Dashboard series of market intelligence reports. The Life Science Dashboard is the most accessible source for current, segment specific, life science market intelligence in the industry. Designed and implemented by industry experts, The Life Science Dashboard provides key market indicators compiled from the survey responses of thousands of qualified researchers actively engaged in the relevant segment applications. Unlike other reports, The Life Science Dashboard features an ata-glance format that provides rapid access to actionable key market indicators in an easy to understand framework. Key indicators shown in each segment specific dashboard include: Market size Market share Market growth and sample/reaction throughput rates Customer satisfaction Propensity to switch Competitive intensity Perceived pricing Top suppliers Technique usage frequency Fastest growing techniques Primary downstream applications Quantitative results are graphically represented for each question and when applicable verbatim quotations are included for qualitative support and clarification. An overview key market indicator dashboard is provided for quick reference. 760 597 9236 www.perceptaassociates.com 2

The Life Science Dashboards from Percepta Associates, Inc. Percepta launched Series One of the Life Science Dashboards in early 2007, designed to establish a benchmark of the existing market landscape. The release of Series Two of each Dashboard furthers our primary objective of regularly sampling the research landscape to give Dashboard readers a comprehensive, relevant and dynamic view of how important life science markets are adapting to new products, new competitors, and new sales and marketing strategies. Note that throughout this report, you will see the following icons: % Increase from 2007 Life Science Dashboard % Decrease from 2007 Life Science Dashboard These icons and their associated values represent the changes observed in the 2008 Cell Culture Dashboard data set in comparison to the corresponding data from the 2007 Cell Culture Dashboard. For example, in Figure 15 of this report, the percentage of respondents using growth and attachment factors on a weekly basis is 33.1%, an increase of 6.2 percentage points over the 2007 Cell Culture Dashboard value of 26.9%. There are instances where comparisons to the 2007 Cell Culture Dashboard are not possible, due to rewording of questions for the purposes of clarity that were necessary to improve the overall quality of the data and the final Dashboard report in general. Life Science Dashboards Available. Gene Expression Profiling Dashboard April 2008 Series Two Cat. # 0804GEP February 2007 Series One Cat. # 0702GEP Gene Silencing Dashboard September 2008 Series Two Cat. # 0809GSL February 2007 Series One Cat. # 0702GSL Nucleic Acid Separation Dashboard November 2008 Series One Cat. #0811SEP Nucleic Acid Amplification Dashboard Coming Soon Series Two Coming Soon January 2007 Series One Cat. # 0701NAA Transfection Dashboard Coming Soon Series Two Coming Soon January 2007 Series One Cat. # 0701TFN Cell Culture Dashboard December 2008 Series Two Cat. # 0812CCT January 2007 Series One Cat. # 0702CCT Nucleic Acid Purification Dashboard Coming Soon Series Two Coming Soon January 2007 Series One Cat. # 0701NAP For more information on these Life Science Dashboards and upcoming Dashboards please visit www.lifesciencedashboard.com. 760 597 9236 www.perceptaassociates.com 3

About Percepta Associates, Inc. The Life Science Dashboard is produced by Percepta Associates, Inc. Percepta is a strategic consultancy firm focused on helping life science tools companies. Since our founding in 2005 we have provided a broad range of specialized market research, strategic and tactical planning services to life science tool providers. Our team is comprised of industry experts with first hand practical experience and a proven track record of successful leadership in life science companies. It is precisely our indepth knowledge and practical experience in this segment that makes Percepta unique. Percepta offers custom primary market research services, in addition to periodically publishing a number of segment specific Life Science Dashboards. Our primary research services utilize the following research methodologies online surveys, focus groups and telephone or face-to-face in-depth interviews to capture the voice of the customer. Percepta maintains a profiled panel of over 33,000 life scientists worldwide. This panel provides a rich and qualified source of timely input for the Life Science Dashboard surveys. Our panel was built, and is continually supplemented, with researcher contacts from scientific societies, journals, scientific meeting participants and other qualified sources. For more information about Percepta s market research and consulting services please visit our www.perceptaassociates.com or call 760 597 9236. 760 597 9236 www.perceptaassociates.com 4

Figure 6: Percentage of Respondents Performing Various Life Science Techniques at Least a Few Times per Year Q7. How often do you perform each of the following techniques? Please make one selection for each technique (required). DNA Isolation/Purification Standard PCR Nucleic Acid Electrophoresis Protein Expression 79.0% 78.0% 74.5% 74.5% RNA Isolation/Purification 69.2% DNA Sequencing 63.2% Real-Time PCR/qRT-PCR 62.8% RNAi/siRNA Experiments 51.8% Reporter Gene Assays 50.8% Labeling Nucleic Acids/Probes 44.2% Four techniques performed by more than 70% of respondents at least a few times per year Genotyping Microarray Analysis in vitro Translation mirna Analysis 25.5% 29.1% 36.0% 39.4% n=419 0% 20% 40% 60% 80% 100% 760 597 9236 www.perceptaassociates.com 5

Figure 9: Percentage of Respondents Using Basal Media Q9. How often do you use the following types of mammalian cell culture reagents? Please make one selection per row (required). Do not currently use, and no plans to use in the next 12 months 2.5% Do not currently use, but plan on using in the next 12 months 4.0% A few times per year 3.2% A few times per month 7.0% Frequency of Performance 2007 LS Dashboard Weekly -4.0% A few times per month 0.0% 90.3% of respondents use basal media on at least a monthly basis Weekly 83.3% A few times per year -0.6% Do not use but plan to in the next 12 months Do not use no future plans to use 4.0% 0.6% n=402 760 597 9236 www.lifesciencedashboard.com 6

Figure 19: Respondent s Primary Supplier for Balanced Salt Solutions Q10. If you use the following cell culture medias or supplements, please select your primary supplier. Hyclone/Thermo Fisher (includes Pierce) 6.3% Cambrex 1.7% Other 8.3% Primary Supplier 2007 LS Dashboard Invitrogen 2.4% Sigma-Aldrich 3.4% Homemade Reagents -4.2% CellGro by Mediatech -3.3% CellGro by Mediatech 9.0% Hyclone/Thermo Fisher -1.8% Cambrex -2.1% Over half of respondents named Invitrogen as their primary supplier Homemade Reagents 9.3% Invitrogen/Gibco 55.1% Sigma-Aldrich 10.3% n=301 760 597 9236 www.lifesciencedashboard.com 7