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ANKA Systems, Inc. Digital Imaging for Ophthalmology Contents 02 Company Overview 03 EyeRoute Products Overview 04 EyeRoute Application 08 EyeRoute Components

Digital Imaging for Ophthalmology Who We Are At Anka Systems, Inc. (ANKA), we offer a onestop solution for capturing, storing, and distributing digital images, tailored to the needs of the ophthalmology industry. Our digitizing system, EyeRoute, is specifically designed for handling the growing number of digital images used by today's ophthalmology hospitals. In addition, we provide complete project management and system integration services to allow a smooth transition from film to digital images. Working closely with one of the top eye institutes in the world, Anka has spent more than a year developing the EyeRoute product line. The result is an affordable system that meets the highest standards for reliability and ease of use. Our system allows doctors to access images instantly from anywhere. In addition, a highly redundant architecture provides for maximum availability. Anka Systems is exclusively focused on delivering the best technology solutions to ophthalmology hospitals. As an Anka customer, you'll be working with the finest technologies and technologists the market has to offer. EyeRoute Products EyeRoute integrates the best image-capturing, storage, viewing, monitoring, and networking technologies available today. Considering the budget constraints of typical ophthalmology hospitals, EyeRoute products have been specifically designed as modular increments thereby giving hospitals the flexibility to scale as their particular needs grow. This means that the initial deployment budget for multiple capture stations managed by central storage and monitoring systems can be less than two hundred thousand dollars. Yet, by adding optional modules, it can grow to a comprehensive, integrated system that can meet the current and future needs of any ophthalmology hospital. Applications FA, Color, Red Free, ICG Slit lamp, Echography, OCT Stereoscopy, Time Series Other digital imaging technologies Reading center EyeRoute Services Consulting Services: Project management Cost saving analysis Requirement definition and refinement Functional system analysis Commercial software analysis HIPPA/security analysis Network requirements analysis Functional and cost trade off System Integration Services: External systems integration (HIS/Modality) System design Implementation, deployment, validation Infrastructure monitoring service Technical support Key Customer Benefits Given the comprehensive products and services Anka offers, customers would be able to make a rapid transition to the digital imaging system at a minimum cost. Our product architecture also allows our customers to expand their system with value added features as their needs grow. Scalable can grow to largest hospitals Reliability full redundancy of components Low-cost very competitive pricing modular architecture Low risk proven vendors Highest functionality Anka provides the best products and services in the Ophthalmology industry. Contact us and get started on your way to the digital world. 2

Digital Imaging for Ophthalmology EyeRoute Products Overview Core System: EyeRoute-CS: MRP capture station EyeRoute-View: MRP viewing station EyeRoute-Stor: Central database & storage EyeRoute-Mon: Monitoring system Options: EyeRoute-WOrDS: Work order data system EyeRoute-Web: Web viewing EyeRoute-HL7: HIS integration system EyeRoute-DICOM: DICOM interface system EyeRoute Product Overview Modality And Capture DICOM Gateway Capture and Hospital Information System (HIS) HIS Gateway Capture Satellite Hospital Work Order Capture Web Server Web Users & DB Capture Diagnostic Display System Monitoring 3

Digital Ophthalmology Applications EyeRoute Entry-Level Configuration Ophthalmology hospitals can finally deploy high quality digital imaging systems at affordable prices. Anka System s EyeRoute products provide a modular incremental approach to deploying digital ophthalmology systems. The basic hospital system consists of capture stations, viewing stations, central patient records, and central storage. This entry-level configuration allows hospitals to capture studies on multiple capture stations, store studies on a central network, view the studies from multiple locations, and back the studies up to DVDs for disaster recovery. Modality And Capture EyeRoute Entry-Level Configuration Capture and Capture Diagnostic Display 4

Digital Ophthalmology Applications EyeRoute Redundant and Monitoring To improve the availability of data in the central location, a redundant central patient records and database can be installed, and an extensive web-based operations monitoring system, EyeRoute-Mon can be installed. Modality And Capture EyeRoute Redundant and Monitoring Capture and Capture Diagnostic Display System Monitoring 5

Digital Ophthalmology Applications EyeRoute Satellite Hospital Support To handle studies captured in satellite hospitals, Anka Systems provides EyeRoute-Cache, a special viewing station with a cache that can store many months worth of studies locally. The capture station also supports a local copy of the study database. Because both the image storage and the database are local, studies can be acquired even when the network to the central hospital is unavailable. This system also automatically copies these satellite hospital studies to the central storage. The copied satellite hospital studies can then be quickly accessed by central hospital users as well. EyeRoute Satellite Hospital Support Modality And Capture Capture and Capture Satellite Hospital Capture Capture & DB Diagnostic Display System Monitoring 6

Digital Ophthalmology Applications EyeRoute Full System Configuration Additional modules can be added to the system to increase EyeRoute s functionality and automation: EyeRoute-HL7 automates the input of patient demographic information and provides image availability information back to the hospital information systems. EyeRoute-Web allows access to patient data and images from anywhere. EyeRoute-DICOM provides the ability to retrieve and store DICOM based studies. EyeRoute-WOrDS (Work Order Data System) automates order generation and study tracking information. EyeRoute Full System Configuration Modality And Capture DICOM Gateway Capture and Hospital Information System (HIS) HIS Gateway Capture Satellite Hospital Work Order Capture Capture Web Server Web Users & DB Diagnostic Display System Monitoring 7

Ophthalmology Capture EyeRoute-CS EyeRoute-CS provides high performance high quality image capturing. EyeRoute-CS from the MRP Group offers ophthalmology photographers a completely automated high performance solution for capturing high quality images. All the menus and functions are intuitive and provide photographers with fast easy access to image operations. EyeRoute-CS captures sequential images within one second (important for Angiograms) and displays images on the monitor in real time. This high speed processing increases the volume of patient s hospitals can photograph. Captured studies are saved to a centralized storage and database so all viewing stations can retrieve studies quickly. All the operations and procedures such as camera configuration and control, elapse time measurement and auto image enhancement are completely automated. EyeRoute-CS also uses a full sized CCD chip allowing visual fields to be the same size as film based studies. Functions High performance and high speed image capture, loading and enhancements Color, FA and ICG image capture with dual FA and ICG timers Easy to use ophthalmology measurement tools such as GLD, MPS and PDT Create and search patient records Export to email, PowerPoint and files Import other modalities via JPG/TIFF Stereo pair display and scrolling Proof sheet display and printing Works with standard fundus lenses Full film sized 3Kx2K CCD 8

Ophthalmology EyeRoute-View EyeRoute-View provides high quality image access for patient diagnosis. EyeRoute-View from the MRP Group offers ophthalmologists a complete high quality solution for study diagnosis and image processing. EyeRoute-View provides easy to use ophthalmology specific measurement tools such as GLD, MPS, and PDT. The viewer also provides extensive image manipulation functions such as stereo viewing and scrolling, cine viewing, thumbnails, zoom, contrast, invert, and automatic image depth. All the menus and functions are intuitive and provide fast easy access to image operations. The user interface is identical to EyeRoute-CS simplifying the learning curve. Functions Provides high performance and high speed image loading and manipulation Easy to use ophthalmology measurement tools Search and load studies via patient records Import other modalities via JPG and TIFF Export images to email, PowerPoint and files Stereo image pair display and scrolling Proof sheet display and printing 9

Ophthalmology EyeRoute-Stor EyeRoute-Stor provides enterprise quality patient record and image storage. Satellite Hospital Central Hospital Record Synchronization Capture Capture Image Replication EyeRoute-Stor has been designed for and is tightly integrated with ophthalmology capture stations. This system simplifies study management by automating data replication, synchronization, and fail-over tasks to provide always-online study access. Satellite hospitals are also supported through distributed storage and patient records. EyeRoute-Stor is designed to work through multiple system failures such as disk, DVD, network, and server failures. Functions Patient Records Multiple patient record copies for redundancy with easy fail over Satellite and Central hospital patient record synchronization Satellite hospitals can work as standalone systems Image Multiple image copies for redundancy Removable DVDs for off-site disaster recovery Automatic fail over to backup image copies Replication of satellite hospital images to central storage Satellite hospitals can work as standalone systems Optional Features Scales to multiple terabytes on an as needed basis Redundant configuration provides immediate fault recovery 10

Ophthalmology Monitoring System EyeRoute-Mon EyeRoute-Mon monitors all operational aspects of the EyeRoute system. System Monitoring Work Order Web Server Capture Network Elements HIS Gateway DICOM Gateway EyeRoute-Mon is an application that monitors all aspects of the EyeRoute system (computer servers, storage, network and applications) to determine hardware and software failures. EyeRoute-Mon provides automatic email or paging of the administrator when problems are detected and when they are resolved. System administrators can view the current service status, history, etc. via a web browser to determine the system s health, operational status and other statistics. Functions Extensive hardware and software monitoring of all servers including: System availability Network connectivity Component failures Disk usage Processor load Central and satellite site network capacity and performance Web interface for status and statistics reporting Problem notifications via email, pager, or user-defined methods 11

Web Integration for Ophthalmology EyeRoute-Web EyeRoute-Web allows instant access to patient and image data from anywhere. Local Browsers Network Elements Web Server Browsers EyeRoute-Web allows ophthalmologists to access patient demographic and study information over the and Intranet through a browser. This feature allows ophthalmologists to take advantage of accessing high quality images through ubiquitous low cost browser based PCs. EyeRoute-Web provides this web based image access with the high level security required to meet HIPAA compliance using security protocols and encryption technologies. EyeRoute-Web provides diagnostic viewing station like capabilities such as high image quality, stereo viewing and scrolling, thumbnails, cine viewing, zoom, contrast, invert, measurements and automatic image depth. EyeRoute-Web provides a seamless expandable, flexible and reliable system, which allows many users to access ophthalmic images without significant system wide changes and software installation. Functions Rich image processing and viewing functions Image viewing through an browser: Instant access from anywhere for authenticated users Cost-effective manageable solution without additional client software Consultation features including email, reports, image export and import Variable image compression reduces download times Multiple exam viewing simplifies comparisons 12

HIS Integration for Ophthalmology EyeRoute-HL7 EyeRoute-HL7 provides flexible communication with hospital information systems. HIS Gateway Hospital Information System (HIS) Hospital Information Systems (HIS) are used to create a patient s demographic and scheduling information when they make appointments. EyeRoute-HL7 retrieves the patient s demographic and scheduling information from the HIS system through HL7 (Health Level 7) based messages. HL7 is an industry standard format that is used for electrical data exchange within the hospital environment. This interface is useful for procedure automation that requires the retrieval, distribution and validation of patient records and registration of this information to other client components such as the capture stations, work flow for order processing, viewing applications and storage systems. By deploying EyeRoute-HL7, all the manual procedures related to the patient demographic information can be automated. Additionally, EyeRoute-HL7 provides an update capability to report the examination status and medical notes back to HIS for access, billing and transcription purposes. Functions International standard HIS interface (HL7 version 2.3) Translates ADT (admission, discharge, and transfer) messages Bi-directional message communication Receives patient records via HL7 messages Sends image availability via HL7 messages 13

Work Orders for Ophthalmology EyeRoute-WOrDS EyeRoute-WOrDS provides ophthalmology specific order generation and exam tracking. Local Browsers Network Elements Capture Work Order Hospital Information System (HIS) HIS Gateway Browsers EyeRoute-WOrDS (Work Order Data System) is specially designed for the ophthalmology hospital environment and provides work order generation and management capability through a web based user interface. Eye Route-WOrDS provides ophthalmology modalities with work order lists and detailed order instructions for medical photographers. EyeRoute-WOrDS generates the work order list through a web-based user interface. Generated work order lists are stored in the WOrDS database and provided to modality stations. Functions Web-based user interface: Automatic display of admitted patient records Optional manual creation of new patient records Order generation and deletion Order status display One click access to completed orders HIS data synchronization via EyeRoute-HL7 Retrieval of admitted patient records Validation of manually created records Notification of study availability Generates work order lists for capture stations 14

DICOM Integration for Ophthalmology EyeRoute-DICOM EyeRoute-DICOM enables communications with DICOM compatible systems. DICOM Gateway Other DICOM Imaging Systems and Modalities EyeRoute-DICOM allows EyeRoute to communicate with other systems using the DICOM standard. Digital Imaging and Communications in Medicine (DICOM) specifies a network protocol utilizing TCP/IP, defines the operation of Service Classes beyond the simple transfer of data, and provides a mechanism for uniquely identifying information objects as they are acted upon across the network. DICOM is also structured as a multi-part document in order to facilitate extension of the standard. Additionally, DICOM defines information objects not only for images but also for patients, studies, reports, and other data groupings. With the enhancements made in DICOM (Version 3.0), the standard is now ready to deliver on its promise of permitting the transfer of medical images in a multi-vendor environment. Functions DICOM 3.0 support Verification service provider service provider Query/retrieve service provider Report query service provider Basic worklist service provider Lossless image compression Automatic and manual process recovery Automatic image backup 15

` ANKA Systems, Inc. www.ankasystems.com 1616 Anderson Road Suite 108 McLean, VA 22102 USA Tel: 703-714-0700 Fax: 703-714-0701 Contact: Email: info@ankasystems.com Anka Systems, Inc. Anka Systems, Inc. 1616 Anderson Rd. Ste 108, McLean, VA 22102, (703) 714-0700, www.ankasystems.com