William Z. Rymer, MD, PhD Center Director Chief Scientific Officer, The Rehabilitation Institute of Chicago John G. Searle Chair in Rehabilitation Research Professor, BME, McCormick School of Engineering, NU Professor, Physiology, Feinberg School of Medicine, NU w-rymer@northwestern.edu NIH 5R24 HD 050821-08 Yasin Dhaher, PhD Center Associate Director Co-Director of the Robotics/Mechanics Core Senior Research Scientist, The Rehabilitation Institute of Chicago Associate Professor, BME, McCormick School of Engineering, NU Associate Professor, Physical Medicine and Rehabilitation Feinberg School of Medicine, NU y-dhaher@northwestern.edu
Frequently Asked Questions Q : What is the goal of the ENR Infrastructure grant? A : The ENR program involves the application of neuro-engineering principles to neurologic impairments for the promotion of recovery. Q : What and How? A : Pilot funding used to develop novel ideas in collaboration with SMPP s ENR program. Q : Wh0 qualifies? A : Faculty based at universities, medical centers and hospitals across the United States. Q : What can funds be used for? A : Salary; Staff Support; Fellow or student Support; Travel; Subject Fees or Other research related activities 2
Resources Neuroscience Core: Drs. C.J. Heckman Lee Miller Robotics / Mechanics Core: Drs. Sandro Mussa-lvaldi and James Patton Modeling and Simulation Core : Drs. Wendy Murray and Yasin Dhaher Electronics, Technology and Sensing Core : Drs. Derek Kamper and Paolo Bonato 18 Principal Investigators 14 Research Laboratories 13 Technical/ Core Staff
The process ENR PI Goal : Specific Aims page NIH competitive
Pilot Projects Cumulative number of pilot grants funded : 11 current 2 pending 7 closed
Pilot Projects Algorithms Technology Modeling Disease States : SCI Stroke ALS Parkinson s Disease Please see the R24 Conference ; Chicago June 17-18, 2013: URL link to R24 website and access Abstracts and sample Slide presentations: http:www.ric.org/enrconference/
Pilot Projects - Algorithms IDENTIFICATION OF INNERVATION ZONE BASED ON HIGH-DENSITY EMG M-WAVE RECORDINGS IN HEALTHY AND STROKE SUBJECTS Channel Index Sheng Li, MD, PhD Director of the Neurorehabilitation Research Laboratory TIRR Memorial Hermann Hospital Department of Physical Medicine and Rehabilitation University of Texas Health Science Center Houston
Pilot Projects - Algorithms Basic Idea Donald J. Crammond Center for Clinical Neurophysiology, Department of Neurological Surgery, University of Pittsburgh Medical Center,
Pilot Projects - Algorithms Basic Idea Barbero M. Merletti R., Rainoldi A. (2012) Atlas of muscle innervation zones. Springer
Pilot Projects - Algorithms Clinical Feasibility M-Wave vs. MVC MVC difficult to achieve for the low functioning group M-Wave technical difficulty (stimulation artifact)
Pilot Projects - Algorithms M-Wave Axillary fold (musculocutaneous nerve) Electrode array (16 channels) Channel Index Jie Liu, et. al. "Suppression of stimulus artifact contaminating electrically evoked electromyography", NeuroRehabilitation (in press)
Pilot Projects - Algorithms Clinical Feasibility M-Wave vs. MVC 10 9 8 7 6 5 4 3 2 1 0 impaired non-impaired MVC IZ M-wave IZ N = 10 Stroke (high functioning, biceps)
Pilot Projects - Technology WEARABLE SENSOR TECHNOLOGY FOR OBJECTIVE MONITORING OF MOTOR FUNCTION Shyamal Patel, Ph.D. Research Engineer at Harvard Medical School Research Engineer at Spaulding Rehabilitation Hospital Paolo Bonato, Ph.D. Director of the Motion Analysis Laboratory Spaulding Rehabilitation Hospital Associate Professor Department of Physical Medicine and Rehabilitation, Harvard Medical School
Pilot Projects - Technology A USER - CONTROLLED POWERED ANKLE EXOSKELETON TO ASSIST GAIT PROPULSION POST STROKE Air Compressor Control Signal Real-time Processor AP-GRF & Soleus EMG Gregory S. Sawicki, Ph.D. Director, Human PoWeR Laboratory Assistant Professor of Biomedical Engineering Joint Department of Biomedical Engineering University of North Carolina at Chapel Hill North Carolina State University Proportional Myoelectric Propulsion (PMP) Control
Pilot Projects - Technology IMPROVING ASSISTIVE GLOVES FOR STROKE SURVIVORS USING BIOMECHANICAL MODELS AND OPTIMIZATION Na Jin Seo, Ph.D. Assistant Professor Department of Industrial and Manufacturing Engineering University of Wisconsin-Milwaukee
Pilot Projects - Models QUANTITATIVELY IMAGING INTERNAL MUSCLE ACTIVITIES FROM MULTI- CHANNEL SURFACE EMG RECORDINGS Yingchun Zhang, PhD Assistant Professor Department of Biomedical Engineering University of Houston
How? http://www.ric.org/research/centers/enrp/newr24.aspx Thank you