Ahmed BEN HAMIDA,Professor



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ICT WP 2011-12 Challenge 5 : - Objective 5.1: Personal Health Systems (PHS) Objective 5.2: Virtual Physiological Human (VPH) Objective 5.3: Patient Guidance Services (PGS) Objective 5.4: ICT for Ageing and Wellbeing Objective 5.5: ICT Smart, Personalised Inclusion Presented By Ahmed BEN HAMIDA,Professor Head of ATMS research group Advanced Technologies for medical and Signals ATMS Lab LETI, ENIS University of Sfax Tunisia ICT WP 2011-12 Challenge 5 - Objective 5.1: Personal Health Systems PHS Presented By Ahmed BEN HAMIDA,Professor Head of ATMS research group Advanced Technologies for medical and Signals

FP7/ICT 2011-2012 Programme Structure ICT for socio-economic challenges Basic ICT technologies & infrastructures ~ budget shares 1. Network and Service ~26% Infrastructures 2. Cognitive Systems and Robotics ~6% 3. Component and ~17% Systems 4. Digital ~7% Content and Languages ~10% ~11% 5. ICT for Health, Ageing, Inclusion & Gov. ~12% ~9% 6. ICT for Lower- Carbon Economy ~6% ~4% 7. ICT for Manufac. & Enterprise 8. ICT for Learning & Cultural Resources International cooperation, Cooperation in an enlarged Europe, Pre-commercial Procurement ~11% Future & Emerging Technologies (FET) 3 PHS calls in FP7 so far Aspects and areas covered: 1) Mainly chronic disease management, some on prevention (a) Cardiovascular diseases (b) Diabetes (c) Respiratory diseases (d) Renal failure (e) ICT-enabled Artificial Organs (f) Mental disorders (depression, bipolar, stress) (g) Point-of-Care diagnostics portable or handheld systems for multi-analyte screening at primary care (e.g., celiac disease, autoimmune diseases) 2) Support Actions on: RTD roadmap on Personal Health Systems Roadmap on ICT for disease prevention Interoperability of Personal Health Systems

PHS research in ICT WP 2011-12 Topics not adequately addressed in previous calls, e.g.: Management of neurodegenerative diseases Rehabilitation of cerebrovascular/neurological conditions Analysis of multi-parametric data Input to PHS in Work Programme 2011-2012: From the PHS2020 road mapping project ( ) From the study Robotics for Healthcare (final report: ) From PHS 2010 consultation exercise, January 2010 (report: ) Personal Health Systems (PHS) the big picture Data acquisition Data processing & analysis RR[mse c] SBP [mmhg] SCMI [ %] Risk[--] 1500 1000 500 Tilt Symptho ms 200 400 600 800 1000 12 00 140 0 160 0 18 00 200 0 220 0 t [sec] 150 100 50 200 400 600 800 1000 12 00 140 0 160 0 18 00 200 0 220 0 100 t [sec] 50 0 200 400 600 800 1000 12 00 140 0 160 0 18 00 Positive 200 0 VVS 220 0 Risk 0.5 t [sec] 0-0.5 200 400 600 800 1000 12 00 140 0 160 0 18 00 200 0 220 0 t [sec] Other data: clinical, images, lab, genomics Health/call Centre Sensors for multi-parametric monitoring Intelligent analysis Medical expertise Hospital Treatment, Rehabilitation Support to diagnosis decision & treatment Data communication and feedback

FP7 ICT Objective 5.1 Personal Health Systems (PHS) Target Outcome: (a) PHS for remote management of diseases, treatment and rehabilitation FP7 ICT Objective 5.1 Personal Health Systems Target Outcome: (a) PHS for remote management of diseases, treatment and rehabilitation

FP7 ICT Objective 5.1 Personal Health Systems Target Outcome: (a) PHS for remote management of diseases, treatment and rehabilitation Target Outcome: FP7 ICT Objective 5.1 Personal Health Systems (b) Intelligent systems for the analysis of multi-parametric data

FP7 ICT Objective 5.1 Personal Health Systems Target Outcome: (b) Intelligent systems for the analysis of multi-parametric data FP7 ICT Objective 5.1 Personal Health Systems Expected Impact

FP7 ICT Objective 5.1 Personal Health Systems Expected Impact For target outcomes a) and c): For target outcomes a) only: For target outcomes c) only: FP7 ICT Objective 5.1 Personal Health Systems When : Call 7 Budget : 60 M Instruments and Selection: (a) : IPs and STREPs (b) : STREPs only 59.5 M for (a) + (b) (c) CSAs 500k:

Contact persons DG INFSO Unit H1 ICT for Health Personal Health Systems group ICT WP 2011-12 Challenge 5 ICT FOR HEALTH, AGEING WELL, INCLUSION AND GOVERNANCE Strategic Objectives 5.2: Virtual Physiological Human VPH Joël Bacquet ICT for Health DG Information Society & Media European Commission

Outline Part I VPH overview/status Towards full picture of individual s health status Omics -based personalized medicine Biosensors Biochips Environmental Data Genomic data Phenomic data ICT Systems

The Virtual Physiological Human (VPH) concept Based on the ideas of the International Physiome project Baseline: The VPH is a methodological and technological framework using advanced ICT to enable the investigation of the human body as a complex system Inter-disciplinary research (bioinformatics, medical informatics, genomics, medicine) STEP: pioneer FP6 project defined the VPH research roadmap, see VPH NOE Call2: second VPH vision and strategy Goals: Personalised (patient-specific) healthcare solutions Early diagnostics & predictive medicine Understanding diseases for the first time across several biological levels Outline Part II VPH FP7 Call7 & 9

WP2011-12 Objective 5.2 VPH Target outcomes overview: a) Patient-specific predictive computer based models and simulation (including environmental factors) b) ICT tools, services and infrastructures to obtain more elaborate and reusable multi-scale models and larger repositories c) RTD roadmap preparing the ground for a Digital Patient challenge d) Early demonstrators and proof of concept of digital representations of health status. a) and b) IP/STREP 58M c) CSA 1.5M d) STREP 8.5M Focus a) FP7 ICT Objective 5.2 Virtual Physiological Human Patient-specific predictive computer based models and simulation Predictive models & simulation of major diseases integrating medical, biological and environmental data Emphasis on influence of environmental factors on diseases Interaction and integration of environmental factors with other health factors in developing predictive models Applied goals, use and benefits should be demonstrated for a specific clinical need. All major diseases targeted

Focus b) FP7 ICT Objective 5.2 Virtual Physiological Human ICT tools, services and infrastructures to obtain more elaborate and reusable multi-scale models and larger repositories Projects to address at least 1 of the 2 activities: 1. Robustness and reproducibility of VPH models Allowing models to be re-used Standards for models and data Tools to support robustness and reproducibility of models 2. Development of VPH info-structure Sustainable VPH model and data repositories Appropriate tools to support this info-structure Address attributes such as usability and accessibility (community acceptance) Open environment and open-source software Focus c) FP7 ICT Objective 5.2 Virtual Physiological Human RTD roadmap preparing the ground for a Digital Patient challenge Digital representation of the different patients specific models Provide patients with personalised and predictive care The roadmap will provide: Consolidation of research so far Identify and quantify the needs Develop a vision and ICT research agenda for the Digital Patient Instruments/budget: One CSA max funding of 1.5M Call 7

FP7 ICT Objective 5.2 Virtual Physiological Human Expected impacts: For all target outcomes More predictive, individualised, effective and safer healthcare Reinforced leadership of European industry and strengthened multidisciplinary research excellence in supporting innovative medical care Contact/Information DG Information Society and Media Unit ICT for Health Call information: VPH project portfolio: Virtual Physiological team:

ICT WP 2011-12 Challenge 5 - Objective 5.3: Patient Guidance Services (PGS), safety and healthcare record information reuse Nigel Strang ICT for Health DG Information Society & Media European Commission Activity A Patient guidance services for personalised management of health status Engage and assist patients and their entourage in the care process Construct integrators for multiple sources Provide a platform for integration of (PHS) devices Incorporate patient based (VPH) models Provide shared Patient, entourage & clinician decision support Provide services compliance, safety alerts, lifestyle guides, book and choose Contribute to the European infostructure under the Governance of the Network of excellence Submit all services and systems to interoperablity testing and certification (if/where available)

Activity B Reuse of Clinical Data for clinical research and epidemiology Repeat of the topic of call 4 Address legal and interoperability issues Clinical trials, cohort studies, phenotype genotype studies Defining the conditions that enable the reuse of clinical data Exploiting the information gathered in the European Portal Contribute to and use the infostructure Expected impact- Common platform for a wide range of ICT-based healthcare services Improve sustainability of Healthcare services by enabling better use of resources. Increased international competitiveness of European Healthcare Information Services and Software industry. Guidance on healthcare information systems issues in green field member states. Accelerated establishment of interoperability standards and of secure, seamless communication of health data between all involved partners, including patients. Wide-scale epidemiology based on Europe-wide Healthcare information system.

Expected impact- Better medical expertise access in remote areas, via improved decision-support systems Support for patient mobility and patient safety through PHR accessed throughout Europe. Improved disease management and treatment through provision of personalised services. Reinforced participation of patients in care processes and health management. Expected impact- Faster medication innovation and lower costs through a more efficient research process. Wider access for patients to public health information data portals using mobile platforms. Standard mobile solutions for future implementations of closed loop applications.

Leading actors Medical professional organisations Patient representation organisations Member state health service providers Mobile telephone operators Standards development organisations Healthcare record standards Terminologies and ontologies Healthcare software editors Healthcare information providers Contact persons DG INFSO Unit H1 ICT for Health Patient Guidance Services safety and healthcare record information reuse Nigel Strang nigel.strang@ec.europa.eu

Challenge 5 Obj.5.4: ICT for Ageing and Wellbeing European Commission, DG Information Society and Media ICT for Inclusion Unit (H3) Peter.Wintlev-Jensen (at) ec.europa.eu ICT for socio-economic challenges : Improve the quality of life of people, including persons with disabilities and the elderly, supporting their full participation in society by means of ICT Action Plan Policy and awareness raising, shared understanding and common approaches Accelerate investment in and take-up of existing solutions Innovative public procurement, Regional Funds Prepare for the future through research and innovation Supporting (Funding) Programmes 7 th FP, CIP, AAL 36

ICT for Ageing Well A Comprehensive EU Approach Technology Risk Common Policy: ICT & Ageing Well Action Plan Common Technology Roadmap: AALIANCE FP7 Longer-term R&D Advanced, e.g. Robotics, Open platforms 400 M AAL JP Market-oriented R&D Local adaptation Business models >600 M Large scale validation Existing technology Service innovation Business models 60 M CIP ICT PSP Time to Market 5-10 years 2-3 years deployment 37 Call 7 Objective ICT-2011.5.4: ICT for Ageing and Wellbeing Service and social robotics systems for ageing well More efficient care, prolonged independent living and better quality of life of elderly and carers Strengthened global position of European industry in Service robotics Smart and self-adaptive environments prolonging independent living New Proven ICT concepts for early detection of ageing-related risks Substantial potential for increased quality of life and reduction in care costs Global industrial and academic leadership in ICT and Ageing Well RTD roadmaps and Stakeholder coordination Common strategic vision / RTD roadmap for ICT for ageing well in Europe and beyond Comprehensive specific vision on ICT for Ageing at Work New

Service Robotics for Ageing Well Care solutions integrating R&D advances in robotics research and intelligent environments Excluded: R&D on robotics components Providing improved quality of life and efficiency of care for elderly people and their carers Support for daily living and care activities With people present (context detection) Integrated with other smart artefacts, intelligent home space + services Usability, ethics Improving state of the art Smart and Adaptive Environments prolonging Independent Living Flexible care solutions able to provide early detection of individual care needs and support related to ageing E.g. increased risks of falls, depression, sleep deprivation, cognitive decline. Building on long term monitoring of unobtrusive daily behavioural and physiological sensing and analysis Unobtrusive sensing available in future homes Better prediction/prevention & support Advanced reasoning and trend analysis with medical correlation Integrated solutions with adaptive support Validation of results

Call 7 Objective ICT-2011.5.4: ICT for Ageing and Wellbeing Services for elderly people through Pre-Commercial Procurement (PCP) New Effective cooperation and linkage between longer-term research and innovative real-life implementation of robotics based solutions for ageing well New public-private partnerships for sustainable improvements in care provision Strengthened global position of European industry in Service robotics Funding Schemes and Budgets Target Service Robotics for Ageing Well Open Systems, Ref. Architectures, Standards and Home Platforms RTD roadmaps i) Ageing Well Ii) Ageing at Work Indicative Budget 32,5 M 1 M 0.5 M Funding Scheme CP: one IP + STREPs CP: only CSA: one CA or SA only for i) and ii)

Further Information Web Resources Key Contacts ICT & Ageing General Contacts e-inclusion Unit European Commission -Information Society and Media DG Office: BU31 04/50 B-1049 Brussels Email: einclusion@ec.europa.eu Tel: +32 2 295 02 65 Fax: +32 2 295 13 00 Challenge 5 Obj.5.5: ICT for Smart and Personalised Inclusion European Commission, DG Information Society and Media ICT for Inclusion Unit (H3) Luiz.Santos@ec.europa.eu

ICT for socio-economic challenges : Improve the quality of life of people, including persons with disabilities and the elderly, supporting their full participation in society by means of ICT Action Plan Policy and awareness raising, shared understanding and common approaches Accelerate investment in and take-up of existing solutions Innovative public procurement, Regional Funds Prepare for the future through research and innovation Supporting (Funding) Programmes 7 th FP, CIP, AAL 45 Funding R&D and Deployment Supporting Programmes Technology Risk Action Plan 7 th FP longer-term R&D innovative ICT and their integration AAL JP market-oriented R&D cost-efficiency adaptation of ICT to specific demands application-driven R&D large scale trials (of existing technology) innovations on service and organization business case development CIP ICT PSP Time to Market 5-10 years 2-3 years deployment 46

7 th FP Call 7 Objective ICT-2011.5.5: ICT for Smart and Personalised Inclusion DRAFT Tools and infrastructures for mainstream accessibility Advanced human-computer interaction Improved competitiveness of European industry Facilitated and richer social interactions Intelligent and social computing Brain-Neural Computer Interfaces E-Inclusion; E-accessibility Proof of concept and mainstream exploitation International Cooperation Common strategic vision / RTD roadmap 7 th FP Call 7 Objective ICT-2011.5.5: ICT for Smart and Personalised Inclusion DRAFT Users and context-aware, adaptive ICT and services Interoperability of devices, standardization Virtual simulations Synergies with mainstream solutions and application domains Addressing of user acceptance, safety, and privacy Addressing user (beyond functional) requirements User oriented research approach for operational verification of benefits in realistic environments Significant involvement of service providers and industry Viable business models and applications