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Life science companies in Sweden Including a comparison with Denmark addendi

Life science companies in Sweden - Including a comparison with Denmark Anna Sandström, VINNOVA Tage Dolk och Benny Dolk, Addendi AB VINNOVA in collaboration with Stockholm-Uppsala Life Science / UppsalaBIO Västra Götalandsregionen / Göteborg BIO Region Skåne / Medicon Valley Alliance Biotech Umeå BioMedley / New Tools for Health

MSEK deflated MSEK deflated Trade 7 6 5 Pharma 4 3 2 Export Net export Import 1 9 8 7 6 5 4 3 2 1 Medtech Export Import Net export Bild 3

Drug discovery/development Drug delivery Drug production In vitro diagnostics Biotech medical technology CRO Bioproduction Biotech tools and supplies Agrobiotechnology Environmental biotechnology Food related biotechnology Industrial biotechnology Implantable devices Anaesthetic/respiratory devices Electromedical devices Radiation devices Ophthalmic/optical products Dental devices Reusable/single-use devices Healthcare facility products ICT tools Assistive products for disabled The Life Science Industry 29 32, employees in R&D, manufacturing and/or consultancy 4,6 when including marketing and sales

Cluster Profile Sweden Region - Activity category Region Research & Development High net turnover Activity category Manufacturing Consult. Prod dev. Drug discovery/development Drug delivery Drug production In vitro diagnostics Biotech medical technology CRO Bioproduction Biotech tools and supplies Agrobiotechnology Environmental biotechnology Food related biotechnology Industrial biotechnology Implantable devices Anaesthetic/respiratory devices Electromedical devices Radiation devices Ophthalmic/optical products Dental devices Reusable/single-use devices Healthcare facility products ICT tools Assistive products for disabled Low net turnover Number of employees Umeå Uppsala/Stockholm Linköping Gothenburg Others Malmö/Lund

Cluster Profile Sweden Research & Development High net turnover Low net turnover Activity category Manufacturing Consult. Prod dev. Drug discovery/development Drug delivery Drug production In vitro diagnostics Biotech medical technology CRO Bioproduction Biotech tools and supplies Agrobiotechnology Environmental biotechnology Food related biotechnology Industrial biotechnology Implantable devices Anaesthetic/respiratory devices Electromedical devices Radiation devices Ophthalmic/optical products Dental devices Reusable/single-use devices Healthcare facility products ICT tools Assistive products for disabled Region - Umeå Uppsala/Stockholm Linköping Gothenburg Others Malmö/Lund

Employment development in the industry 1997-29 Bild 7

Number of Companies Employment development in the industry 1997-29 7 35 Drug discovery/development Drug delivery 6 3 25 2 2 15 15 1 1 5 5 Drug production Drug production In vitro diagnostics In vitro diagnostics Biotech medical technology Biotech medical technology CRO CRO Bioproduction Bioproduction Biotech tools and supplies Biotech Agrobiotechnology tools and supplies 4 Environmental biotechnology Agrobiotechnology Food related biotechnology Environmental biotechnology Industrial biotechnology Food related biotechnology Implantable devices Industrial biotechnology Anaesthetic/respiratory devices Implantable devices Electromechanical medical devices Radiation devices Anaesthetic/respiratory devices Ophthalmic/optical products Electromedical devices Dental devices Radiation devices Reusable/single-use devices Ophthalmic/optical products ICT tools 5 3 2 1 Dental devices Reusable/single -use devices ICT tools Number of companies 1997 1998 1999 2 21 22 23 24 25 26 27 28 2

Medium (51-25) Small (11-5) Micro (1-1) 6 4 2 5 Employment shares (29) Employment shares (29) Employment shares (29) 1997 1999 21 23 25 27 29 1997 1999 21 23 25 27 29 4 2 1997 1999 21 23 25 27 29 15 1 5 1997 1999 21 23 25 27 29 2 1 45 4 35 3 25 2 15 1 5 1997 1999 21 23 25 27 29 Number of employees Number of employees Number of employees 1997 1999 21 23 25 27 29 Number of companies Number of companies Number of companies Bild 9

Malmö/Lund 19% Swedish regions Umeå 4% Rest of Sweden 7% Uppsala 14% Gothenburg 17% Linköping 2% Stockholm 37%

Denmark Sweden Cluster profiles Profile Sweden n stics al technology e-use devices lity products ucts for disabled High net turnover With product Low net turnover Without product Activity category Manufacturing Consult. Prod dev. nd supplies logy biotechnology otechnology chnology vices spiratory devices devices ces tical products Research & Development y/development Region Region Umeå Umeå Uppsala/Stockholm Uppsala/Stockholm Linköping Gothenburg Others Others Linköping Gothenburg Malmö/Lund Malmö/Lund Zealand Denmark NCS Denmark Bild 11

Structure of the Life Science industry in Sweden and Denmark in 29 No. companies per size class (29) Denmark Sweden Large (>25) Medium (51-25) SMF (1-25) 34 25 6 46 24 675

Life science companies in Sweden & Denmark Umeå (14) Rest of Sweden (21) Rest of Denmark (26) Uppsala (45) Gothenburg (56) Linköping (53) Stockholm (118) Malmö/Lund (6) Zealand (338) Bild 13

Medicon Valley Umeå Rest of Sweden Rest of Denmark Total Stockholm/Uppsala Gothenburg Linköping Medicon Valley Medicon Valley Sweden Denmark Bild 14

Malmö/Lund 19% Många växer Få drar ner Många startar Relativt få nya växer Swedish regions Växande affärsområden Biotech med tech Implantat, CRO etc. Umeå 4% Life Science Danmark Något större än i Sverige Produktion! Rest of Sweden 7% Uppsala 14% Gothenburg 17% Linköping 2% Stockholm 37% Fortsatt stor export

Dynamics Polypeptide Laboratories St Jude Medical AstraTech Diamyd Phadia Quintiles Q-Med Becton Dickinson Atos Medical Medivir/Biophausia Bild 16

Life science companies in Sweden Including a comparison with Denmark addendi