The Swedish Drug Development Pipeline. Dec Sara Gunnerås, Senior Manager Science & IP, SwedenBIO SwedenBIO CEO Summit 2013, AstraZenaca Mölndal
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1 The Swedish Drug Development Pipeline & overview of companies with R&D activities in Sweden Dec Sara Gunnerås, Senior Manager Science & IP, SwedenBIO SwedenBIO CEO Summit 2013, AstraZenaca Mölndal
2 Om uppdraget och rapporten Ta fram en rapport som kan användas för att synliggöra svensk FoU inom läkemedelsektorn, både nationellt och internationellt. Verktyg för att visualisera industrins situation samt behov av stöd. Studien har gjorts årligen sedan 2006 Kartlägga pågående läkemedelsprojekt bland svenska FoU företag. Nytt: Kartläggning av företagen med läkemedelsprojekt Rapporten sammanställs av SwedenBIO med finansiellt stöd från VINNOVA och Business Sweden. AstraZeneca presenteras separat 2
3 Pipeline & Companies 81 projects in phase I-III 67 unique molecules (small & large) 101 companies with R&D activity in Sweden 49 companies with phase I-III projects 3
4 81 projects in clinical trials & 49 companies 100 No No of projects No of companies 4
5 Projects by Phase including previous years 50 No of projects Phase I Phase II Phase III
6 Projects by Phase including previous years 50 No of projects Phase I Phase II Phase III
7 new molecules (not previously reported). 8 projects were reported as put on hold or outlicensed. 7 projects entered next phase. 1 phase 3 project was filed for registration during
8 Therapeutic Areas Cancer Infection CNS Gastro-Intestinal Diabetic/Metabolism Pain Inflammation Endocrinology Obstetrics Cardiovascular Dermatology Other No of projects
9 Small and Large Molecules No of projects small molecules large molecules
10 Choice of Country for Clinical Trial, by Phase 50 No of projects Abroad Sweden & Abroad Sweden 10 0 Phase I Phase II Phase III Result only from questionnaire, 85% response 10
11 AstraZeneca, Global Drug Development Pipeline No of projects AstraZeneca Pipeline Swedish Drug Development Pipeline phase I phase II phase III Source: AstraZeneca annual report
12 Products Abstral - Cancer pain treatment, Orexo Edluar - Insomnia treatment, Orexo Emtrix/Nalox - Discolored and damaged nails, Moberg Derma Episil - Pain for cancer patients suffering from oral mucositis, Camurus Kaprolac - Anti-dandruff Shampoo, Moberg Derma Plenadren - Treatment of adrenal insufficiency, DuoCort Pharma Rapinyl - Cancer pain treatment, Orexo Xerclear - Cold sore treatment, Medivir Zonnic - Nicotine chewing gum, mouth spray, pouch and lozenge, Niconovum Products reported via questionnaire
13 101 Companies with R&D activities in Sweden Umeå, 5% Göteborg, 13% Stockholm/ Uppsala, 62% Malmö/Lund, 20% 13
14 R&D companies - size and employees Micro (0-10 FTE) Small (11-50 FTE) Midsize ( FTE) Large (+250 FTE) 2% 2% 12% 7% 2% 7% 79% 89% 101 companies 8256 employees Source: Information from
15 Top 10 Largest Companies by No of FTE Approx. 30% of pipeline projects Source: Information from
16 Top 10 Largest Companies by Turnover Approx. 30% of pipeline projects Source: Information from
17 Companies with R&D Activities in Sweden (Dec. 2012) A1M Pharma BioCrine Glucox Biotech Neuronova Red Glead Discovery Active Biotech BioInvent International Hansa Medical Neurosearch Sweden Redoxis AcuCort Camurus Helicure NeuroVive Pharmaceutical Respiratorius Acure Pharma Adenovir Pharma Affibody Akinion Pharmaceuticals Albireo Alligator Bioscience Alzacure Alzinova Anamar Apodemus Aprea AstraZeneca Athera Biotechnologies Axcentua Pharmaceuticals Axelar Betagenon Bioarctic Neuroscience BioChromix Pharma Cantargia Cardoz Cebix Chemilia ChronTech Pharma ClanoTech Cortendo Creative Antibiotics Sweden DermaGen Dextech Medical Diamyd Medical Dilafor Dilaforette Duecom Plus-A Edio HealthCare Eurocine Vaccines Glactone Pharma GliGene Hyron BioMedical Immun System I.M.S. Immunicum InDex Pharmaceuticals Isifer AB Isofol Medical Kancera Karo Bio KDev Exploratory KDev Oncology LIDDS Lipidor Lipigon Pharmaceuticals Lipopeptide Medivir Metakalinin Moberg Derma Molecules of Man Northern Light Pharmaceuticals NovaSaid Oasmia Pharmaceutical Omnio Healer Umeå Oncopeptides Oncorena Orexo OxThera Pep-Tonic Medical Pergamum Pharmalink Pharmalundensis Pharmanest PledPharma Premacure Premune Recopharma Strongbone Scandinavian Biopharma Swedish Orphan Biovitrum Synphora TikoMed Toleranzia Umecrine Cognition Umecrine Mood Velit Biologics Vicore Pharma WilsonTherapeutics Vivolux WntResearch XImmune
18 Tack till alla som varit med och bidragit till rapporten! Current and previous pipeline reports may be downloaded from:
The Swedish Drug Development Pipeline. December 2013. & overview of Swedish companies with R&D activities in Sweden
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