CURRICULUM VITAE of Dick Frans SWAAB

CURRICULUM VITAE of Dick Frans SWAAB Contents Abbreviated curriculum vitae 2 Full Curriculum vitae Education 7 Professional career 7 Awards and honors 7 Functions and committees 8 Chairs held by NIBR members 11 Member editorial boards 11 Courses 12 Ph.D. theses 12 supervisor 12 promotor 12 co-promotor 16 co-referent/external referent 16 Ph.D. committee member 16 International conferences organized 19 Dutch meetings organized 20 Some work visits abroad 21 Guest collaborators 22 Some external funds 26 Teaching 28 students 28 university lectures 34 Publications 48 Monographs 49 Articles in journals 50 Book chapters 71 Books edited 83 Reports and columns 85 Abstracts 91 Papers read (type of lecture indicated 1997-present) 120 Meetings with the press 141 Swaab's/NIN research in national and international television/radio programmes 151 Dick Swaab's work referred to in the media 153 Matters relating to Wij Zijn ons Brein (reviews etc.) 156 1

Abbreviated Curriculum Vitae for Dick F. Swaab Name: Dick Frans Swaab Date of birth: 17-12-1944 Education: 1963 Final examination Amsterdams Lyceum 1968 MD (Medicine, UvA) 1970 Ph.D. Thesis: Factors influencing neurosecretory activity of the supraoptic and paraventricular nuclei in rat. A histochemical and cytochemical study. Mentor: Prof. dr. J. Ariëns Kappers. 1972 general physician Professional career 1975-1978 Acting director of the Netherlands Institute for Brain Research, an institute of the Royal Netherlands Academy of Arts and Sciences (KNAW) 1978-2005 Director of the Netherlands Institute for Brain Research 1979- now Professor of Neurobiology at the Medical Faculty, UvA. 1985 Founder and, until 2005, Director of the Netherlands Brain Bank 1978- now Leader Research team Neuropsychiatric Disorders, Neth. Inst for Neuroscience. Editorial activities (selected) Neurobiology of Aging, Progress in Brain Research, Brain Research Series (Elsevier), series Editor of the 3 rd new series of the Handbook of Clinical Neurology (24 volumes published, > 30 volumes planned), Elsevier, Editorial board of Encyclopedic Reference of Neuroscience (Field editor of Neuroendocrinology), Springer Awards and Honors 1976 'Snoo-van 't Hoogerhuijs' prize (together with Dr. W.J. Honnebier) for work in the field of fetal neuroendocrinology. 1987 Holst lecture', T.U. Eindhoven and N.V. Philips 'De klok in onze hersenen', December 12. 1990 'Hugo van Poelgeest' prize for the Netherlands Brain Bank as an alternative for animal experiments, June 26.Journal of Neural Transmission (36, 195-215, 1975) paper awarded "Citation Classic" status in Current Contents 33, no. 30, p. 16. 1995 Nature paper on transsexuality discussed in Nature 378, 15-16, 1995, "Another important organ". Selected by Discover for the top 100 science stories of 1995. 1996 Emil Kraepelin Guest Professorship 1996, Max-Planck-Institut für Psychiatrie, Munich, Germany. 1998 Royal Honour, Knight in the Order of the Netherlands Lion bestowed by her Royal Highness Queen Beatrix of the Netherlands. 1998/now Guest Professor of Anhui Medical University, Hefei, Anhui, PR China. 1999/now Guest Professor of Capital University of Medical Sciences, Beijing, P.R. China. 2000 10 th David de Wied lecture Alzheimer research, the beginning of a better end (in Dutch) at the Educatorium, University of Utrecht, 14 April 2000. Gynaecongres lecture 2000, "The clever but vulnerable head of the unborn child" Millennium Gynaecongres, May 23 and 26, 2000, Beatrixtheater, Jaarbeurs, Utrecht Federa Prize 2000, Federation of Medical Scientific Societies, November 17, 2000, RAI, Amsterdam, for scientific work in biomedical determinants of Alzheimer s disease 2002 GIRES (Gender Identity Research and Education Society) award 2002 for the article Male-to-Female Transsexuals Have Female Neuron Numbers in a Limbic Nucleus. (Kruijver et al., J. Clin. Endocrinol. Metabol. 2034-2041 Alzheimer s Association Award: Lifetime Achievement Award in Alzheimer s Disease Research. Received at the 8 th International Conference on Alzheimer s Disease and Related Disorders in Stockholm, Sweden, 21 July 2003 School of Behavioral and Cognitive Neurosciences New Year s Lecture 2003. Exploring the brain: a search for our selves Honorary member of the installation committee of the journal on Gender Identity Disorders, the GID Journal 2004 The Brain Foundation Lecture Sexual Differentiation of the Human Brain. June1, Doorwerth,the Netherlands. 2005/6 Visiting Professorship in Sleep Medicine (Amer.Ass.of Sleep Med.& Pfizer) at Stanford, CA, USA. Guest Professor at the Beijing Institute of Radiation Medicine from 1 October 2005 to 31 December 2008 2

2007 Guest Professor at Zhejiang University, Hangzhou, PR China. 2008 Academy medal for his role in national and international neuroscience (fundamental to applied), for his initiative to start the Netherlands Brain Bank, and for his research in Alzheimer's disease. Two lectures for the opening of the Academic Year on the invitation of Gezondheids- en Levenswetenschappen, Faculty of Aard- en Levenswetenschappen, Vrije Universiteit, Amsterdam. Title: Education and Environment have only a minor effect on us. Most of our characteristics are inborn. 2009 The "Prof. Nico Bakker Lecture" van de Nederlandse Vereniging voor Urologie, 14 November, Martini Plaza, Groningen. 2010 Honorary member of Brein in Beeld 2011-14 Chao Kuang Piu Chair of Zhejiang University, Hangzhou, P.R. China. Ph.D. theses D.F. Swaab was mentor of 77 Ph.D students, 14 of whom became full professor. The following PhD students received an award or other accolades: 1989 A. Kalsbeek Incentive Prize of the Amsterdam Neurological Society, Professor of Experimental Neuroendocrinology, University of Amsterdam, 2012 1991 E. Goudsmit Sandoz Prize for Endocrinology 1992 1993 H.B.O.M. Honnebier Cum Laude. Organon Prize for Endocrinology 1994 1993 E. Aronica Cum Laude 1995 P.J. Lucassen Cum Laude, Organon Prize for Endocrinology 1996, appointed Professor of Structural & Functional Plasticity of the Nervous System at the University of Amsterdam in 2011 1996 J.N. Zhou The Netherlands Society for Endocrinology Thesis Prize 1997 1996 A. Salehi Boerhaave Aanmoedigingsprijs 1998. 1997 E.J.W. van Someren Cum Laude. Young Investigators Award by the International Society for Chronobiology in 1997. 1998 B.A.Th.F. Gabreëls Organon Prize for Endocrinology 1999. 1998 W.J.G. Hoogendijk Ramaermedaille for Psychiatry 1999 and the International Society for Biological Psychiatry Scientific Award for Young Scientists, 1999. 1999 Paul Dijkhuizen Greiner Award for best Ph.D. thesis on gene therapy of 1999. 2000 Tatjana Ishunina Russian thesis (2003) Summa Cum Laude. 2004 F.P.M. Kruijver GIRES research award 2004 Publications D.F. Swaab has published over 490 papers in SCI journals and 200 chapters in books. He is editor of 24 books. He is series editor (3 rd series) of the renowned Elsevier Handbook of Clinical Neurology, of which over 30 volumes are planned and of which 24 volumes have already appeared. Swaab's H-factor is: 70 He is author of: - The Human Hypothalamus. Basic and Clinical Aspects. Part I: Nuclei of the Hypothalamus, Handbook of Clinical Neurology, Elsevier, Amsterdam, approx. 1000 pp, 2003/2004. - The Human Hypothalamus. Basic and Clinical Aspects. Part II: Neuropathology of the Hypothalamus and Adjacent Brain Structures. Handbook of Clinical Neurology, Elsevier, Amsterdam, approx. 1000 pp, 2003/2004. - Wij zijn ons brein: van baarmoeder tot Alzheimer. Uitgeverij Contact, Amsterdam 2010. The book has appeared in Chinese and German translations and English and Italian translations are being prepared and are expected to be published in 2012. A few key topics and publications: Sexual differentiation of the brain - Swaab, D.F. and E. Fliers - A sexually dimorphic nucleus in the human brain. Science 228, 1112-1115, 1985. - Swaab, D.F. and M.A. Hofman - An enlarged suprachiasmatic nucleus in homosexual men. Brain Res. 537, 141-148, 1990. - Zhou, J.N., Hofman, M.A., Gooren, L.J.G. and Swaab, D.F. - A sex difference in the human brain and its relation to transsexuality. Nature 378: 68-70, 1995. 3

- Garcia-Falgueras, A. and Swaab, D.F. - A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. Brain 131: 3132-3146, 2008. - Swaab, D.F. - Sexual orientation and its basis in brain structure and function. Proc. Natl. Acad. Sci. USA 105: 10273-10274, 2008. Alzheimer's disease - Swaab, D.F. - Brain aging and Alzheimer's disease: "wear and tear" versus "use it or lose it". Neurobiol. Aging, 12, 317-324, 1991. - Salehi, A., Verhaagen, J., Dijkhuizen, P.A., Swaab, D.F. - Colocalization of high affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease. Neuroscience 75: 373-378, 1996. - Salehi, A., Dubelaar, E.J.G., Mulder, M., Swaab, D.F. - Decreased activity of nucleus basalis neurons in Alzheimer s disease is ApoE type dependent. PNAS 95: 11445-11449, 1998. - Scherder, E.J.A., Sergeant, J.A., Swaab, D.F. - Pain processing in dementia and its relation to neuropathology. Lancet Neurol. 2: 677-686, 2003. - Ishunina, T.A., Swaab, D.F., Fischer, D.F. - Estrogen receptor alpha splice variants in the medial mamillary nucleus of Alzheimr's disease patients: identification of a novel MS1 isoform. J. Clin. Endocrin. Metab. 90: 3757-3765, 2005. Submission of sequence data to GenBank, nucleotide sequence bankit651211 AY750962 - Dubelaar, E.J.G., Mufson, E.J., Ter Meulen, W., Van Heerikhuize, J.J., Verwer, R.W.H., Swaab, D.F. Increased metabolic activity in nucleus basalis of Meynert neurons in elderly individuals with mild cognitive impairment as indicated by the size of the Golgi apparatus. J. Neuropathol. Exptl. Neurol. 65: 257-266, 2006. - Ishunina, T.A. and Swaab, D.F. - Age-dependent ERα MB1 splice variant expression in discrete areas of the human brain. Neurobiol. Aging 29: 1177-1189, 2008 - Wu, Y.-H., Fischer, D.F., Kalsbeek, A., Garidou-Boof, M.-L., Van der Vliet, J., Pirovano, C., Liu, R.-Y., Zhou, J.N., Swaab, D.F. - Pineal clock gene oscillation is disturbed in Alzheimer's disease, due to functional disconnection from the "master clock". FASEB J. 20: E1171-E1180, 2006 - Riemersma-van der Lek, R.F., Swaab, D.F., Twisk, J., Hol, E.M., Hoogendijk, W.J., Van Someren, E.J. - Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents of group care facilities: a randomized controlled trial. JAMA 299: 2642-2655, 2008 Parkinson s disease - Hoogendijk, W.J.G., Pool, C.W., Troost, D., Van Zwieten, E.J. and Swaab, D.F. - Image-analyzer-assisted morphometry of the locus coeruleus in Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. Brain, 118, 131-143, 1995 * Material from this paper was selected by the journal to serve as cover illustration. - Hoogendijk, W.J.G., Purba, J.S., Hofman, M.A., De Vos, R.A.I., Jansen, E.N.H., Swaab, D.F. - Depression in Parkinson s disease is not accompanied by more corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus. Biol. Psych. 43: 913-917, 1998. - Scherder, E.J.A., Wolters, E., Polman, C., Sergeant, J., Swaab, D. - Pain in Parkinson's disease and multiple sclerosis; its relation to the medial and lateral pain systems. Neuroscience and Biobehavioral Rev. 29: 1047-1056, 2005. - Fronczek, R., Overeem, S., Lee, S.Y.Y., Hegeman, I.M., Van Pelt, J., Van Duinen, S.G., Lammers, G.J., Swaab, D.F. - Hypocretin (orexin) loss and sleep disturbances in Parkinson's disease. Brain 130: 1577-1585, 2007. - Bossers, K., Meerhoff, G., Balesar, R., Van Dongen, J.W., Kruse, C.G., Swaab, D.F., Verhaagen, J. - Analysis of gene expression in Parkinson's disease: possible involvement of neurotrophic support and axon guidance in dopaminergic cell death. Brain Pathol. 19: 91-107, 2008 Depression - Raadsheer, F.C., Van Heerikhuize, J.J., Lucassen, P.J., Hoogendijk, W.J.G., Tilders, F.J.H., D.F. Swaab - Increased corticotropin-releasing hormone (CRH) mrna in the paraventricular nucleus of patients with Alzheimer's disease or depression. Am. J. Psychiatry 152, 1372-1376, 1995. - Zhou, J.N., Riemersma, R.F., Unmehopa, U.A., Hoogendijk, W.J.G., Van Heerikhuize, J.J., Hofman, M.A. and Swaab, D.F. - Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression. Arch. Gen. Psychiatry 58: 655-662, 2001. - Lucassen, P.J., Müller, M.B., Holsboer, F., Bauer, J., Holtrop, A., Wouda, J., Hoogendijk, W.J.G., De Kloet, E.R., Swaab, D.F. - Hippocampal apoptosis in major depression is a rare event and absent from subareas at risk for glucocorticoid overexposure. Am. J. Pathol. 158: 453-468, 2001. 4

- Bao, A.-M., Hestiantoro, A., Van Someren, E.J.W., Swaab, D.F., Zhou, J.N. Colocalization of corticotrophin releasing hormone and estrogen receptor-α in the paraventricular nucleus of the hypothalamus in mood disorders. Brain 128: 1301-1313, 2005. - Meynen, G., Unmehopa, U.A., Van Heerikhuize, J., Hofman, M.A., Swaab, D.F. - Increased arginine vasopressin mrna expression in the human hypothalamus in depression: a preliminary report. Biol. Psychiatry 60: 892-895, 2006 - Meynen, G., Unmehopa, U.A., Hofman, M.A., Swaab, D.F., Hoogendijk, W.J. - Hypothalamic oxytocin mrna expression and melancholic depression. Mol. Psychiatry 12: 118-119, 2007 - Wang, S.S., Kamphuis, W., Zhou, J.N., Swaab, D.F. - Gene expression analysis in the human hypothalamus in depression by Laser Micro-Dissection and Real Time PCR: the presence of multiple receptor imbalances. Mol. Psychiatry 13: 786-799, 2008. - Chen, X.N., Meng, Q.Y., Bao, A.M., Swaab, D.F., Wang, G.H., Zhou, J.N. - The involvement of retinoic acid receptor-α in corticotropin-releasing hormone gene expression and affective disorders. Biol. Psychiatry 66: 832-839, 2009. Eating disorders and metabolism - Goldstone, A.P., Unmehopa, U.A., Swaab, D.F. - Hypothalamic NPY and AGRP are increased in human illness but not in Prader-Willi syndrome and other obese subjects. J. Clin. Endocrinol. Metab. 87: 927-937, 2002. - Swaab, D.F., Purba, J.S. and Hofman, M.A. - Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: A study of five cases. J. Clin. Endocrin. Metab. 80(2):573-579, 1995. - Alkemade, A., Unmehopa, U.A., Wiersinga, W.M., Swaab, D.F., Fliers, E. - Glucocorticoids decrease TRH mrna expression in the paraventricular nucleus (PVN) of the human hypothalamus. J. Clin. Endocrin. Metab. 90: 323-327, 2005. - Unmehopa, U.A., Van Heerikhuize, J.J., Spijkstra, W., Woods, J.W., Howard, A.D., Zycband, E., Feighner, S.D., Hreniuk, D.L., Palyha, O.C., Guan, X.-M., MacNeil, D.J., Van der Ploeg, L.H.T., Swaab, D.F. - Increased melanin concentrating hormone receptor type I (MCH1R) in the human hypothalamic infundibular nucleus in cachexia. J. Clin. Endocrin. Metab. 90: 2412-2419,2005. - Fronczek, R., Lammers, G.J., Balesar, R., Unmehopa, U., Swaab, D.F. - Hypothalamic hypocretin (orexin) system is not affected in Prader-Willi syndrome. J. Clin. Endocr. Metab. 90: 5466-5470. MS - Huitinga, I., De Groot, C.J.A., Van der Valk, P., Kamphorst, W., Tilders, F.J.H., Swaab, D.F. - Hypothalamic lesions in multiple sclerosis. J. Neuropath. Exptl. Neurol. 60: 1208-1218, 2001. - Huitinga, I., Erkut, Z.A., Van Beurden, D., Swaab, D.F. - Impaired hypothalamus-pituitary-adrenal axis activity and more severe multiple sclerosis with hypothalamic lesions. Ann. Neurol. 55: 37-45, 2004. - Koning, N., Swaab, D.F., Hoek, R.M., Huitinga, I. - Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions. J. Neuropathol. Exp. Neurol. 68: 159-167, 2009 Human postmortem cell culture - Dai, J.P., Swaab, D.F., Buijs, R.M. - Recovery of axonal transport in dead neurons. Lancet 351: 499-500, 1998. - Verwer, R.W.H., Hermens, W.T.J.M.C., Dijkhuizen, P.A., Ter Brake, O., Baker, R.E., Salehi, A., Sluiter, A.A., Kok, M.J.M., Müller, L.J., Verhaagen, J., Swaab, D.F. - Cells in human post-mortem brain tissue slices remain alive for several weeks in culture. FASEB J. 16: 54-60, 2002. - Wu, L., Sluiter, A.A., Guo, H.F., Balesar, R.A., Swaab, D.F., Zhou, J.N., Verwer, R.W.H. - Neural stem cells improve neuronal survival in cultured postmortem brain tissue from aged and Alzheimer patients. J. Cellular and Mol. Med. 12: 1611-1621, 2008 Huntington's Disease - Timmers, H.J.L.M., Swaab, D.F., Van de Nes, J.A.P., and Kremer, H.P.H. - Somatostatin 1-12 immunoreactivity is decreased in the hypothalamic lateral tuberal nucleus of Huntington's disease patients. Brain Res. 728: 141-148, 1996. - Aziz, N.A., Swaab, D.F., Pijl, H., Roos, R.A.C. - Hypothalamic dysfunction and neuroendocrine and metabolic alterations in Huntington's disease: clinical consequences and therapeutic implications. Revs. Neurosci 18: 223-251. 5

- Aziz, N.A., Fronczek, R., Maat-Schieman, M.L.C., Unmehopa, U.A., Roelandse, F.W.C., Overeem, S., Van Duinen, S.G., Lammers, G.J., Swaab, D.F., Roos, R.A.C. - Hypocretin and melanin-concentrating hormone in patients with Huntington disease. Brain Pathology 18: 474-483, 2008 Hypertension - Goncharuk, V.D., Van Heerikhuize, J.J., Swaab, D.F., Buijs, R.M. - Paraventricular nucleus of the human hypothalamus in primary hypertension: activation of corticotropin-releasing hormone neurons. J. Comp. Neurol. 443: 321-331, 2001. - Goncharuk, V.D., Buijs, R.M., Swaab, D.F. - Corticotropin-releasing hormone neurons in hypertensive patients are activated in the hypothalamus but not in the brainstem. J. Comp. Neurol. 503: 148-168, 2007. Miscellaneous - Erkut, Z.A., Klooker, T., Endert, E., Huitinga, I., Swaab, D.F. - Stress of dying is not suppressed by high-dose morphine or by dementia. Neuropsychopharmacology 29: 152-157, 2004. - Overeem, S., Van Vliet, J.A., Lammers, G.J., Zitman, F.G., Swaab, D.F., Ferrari, M.D. The hypothalamus in episodic brain disorders. Lancet Neurol. 1: 437-444, 2002. - Verwer, R., Sluiter, A., Balesar, R., Baayen, J., Noske, D., Dirven, C.,Wouda, J., Van Dam, A., Lucassen, P., Swaab, D. - Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin. Brain 130: 3321-3335, 2007. - Raymann, R.J.E.M., Swaab, D.F., Van Someren, E.J.W. - Skin deep: enhanced sleep depth by cutaneous temperature manipulation, Brain 131: 500-513, 2008. - Kreier, F., Swaab, D.F. - History of neuroendocrinology: 'the spring of primitive existence'. In: Finger, S, Boller, F. Tyler, K.L., Eds. Handbook of Clinical Neurology, vol. 95 (3 rd series) History of Neurology, chapter 23, p. 335-360. 6

CURRICULUM VITAE of Dick Frans Swaab, born December 17, 1944, Amsterdam, The Netherlands H-Factor: 70 Education 1963 Final examination 'Amsterdams Lyceum' 1966 Bachelor of Medicine, UvA 1966 Student assistant Netherlands Central Institute for Brain Research NCIBR), Amsterdam 1968 M.D. and doctoral assistant at the NCIBR 1968/71 Internships university clinics of Amsterdam 1970 Ph.D. Thesis, 'Factors Influencing Neurosecretory Activity of the Supraoptic and Paraventricular Nuclei in Rat, a Histochemical and Cytochemical Study' (supervisor: J. Ariëns-Kappers). 1972 General physician (registration 69024173801 as of 31-12-97) Professional career 1975/78 Acting director of the NCIBR (renamed the Netherlands Institute for Brain Research, NIBR, in 1977) 1978-2005 Director of the Netherlands Institute for Brain Research 1979 Professor of Neurobiology at the Medical Faculty, UvA (1 December). 1980 Oratie: Bederven wij de hersenen van onze kinderen reeds voor hun geboorte? (Are we ruining our children's brains even before they are born?) Inaugural lecture, 28 April 1980. Faculteit der Geneeskunde van de Universiteit van Amsterdam. 1985 Initiator and, until 2005, Director of the Netherlands Brain Bank 1978 Team leader of the work group Neuropsychiatric Diseases at the Netherlands Institute for Brain Research/Neuroscience Awards and Honors 1976 'Snoo-van 't Hoogerhuijs' prize (together with Dr. W.J. Honnebier) for work in the field of fetal neuroendocrinology. 1987 'Holst lecture', T.U. Eindhoven and N.V. Philips 'De klok in onze hersenen', December 12. 1990 'Hugo van Poelgeest' prize for the Netherlands Brain Bank as an alternative for animal experiments, June 26. Journal of Neural Transmission (36, 195-215, 1975) paper awarded "Citation Classic" status in Current Contents 33, no. 30, p. 16. 1995 Nature paper on transsexuality discussed in Nature 378, 15-16, 1995, "Another important organ". Selected by Discover for the top 100 science stories of 1995. 1996 Emil Kraepelin Guest Professorship 1996, Max-Planck-Institut für Psychiatrie, Munich, Germany. 1998 Royal Honour, Companion in the Order of the Dutch Lion bestowed by her Royal Highness Queen Beatrix of the Netherlands. 1998 Guest Professor of Anhui Medical University, Hefei, Anhui, PR China. 1999 Guest Professor of Capital University of Medical Sciences, Beijing, P.R. China. 2000 10 th David de Wied lecture Alzheimer research, the beginning of a better end (in Dutch) at the Educatorium, University of Utrecht, 14 April 2000. Gynaecongres lecture 2000, "The clever but vulnerable head of the unborn child" Millennium Gynaecongres, May 23 and 26, 2000, Beatrixtheater, Jaarbeurs, Utrecht Federa Prize 2000, Federation of Medical Scientific Societies, November 17, 2000, RAI, Amsterdam, for scientific work in biomedical determinants of Alzheimer s disease. 2002 GIRES (Gender Identity Research and Education Society) award 2002 for the article Male-to- Female Transsexuals Have Female Neuron Numbers in a Limbic Nucleus. (Kruijver et al., J. Clin. Endocrinol. Metabol. 2034-2041. Alzheimer s Association Award: Lifetime Achievement Award in Alzheimer s Disease Research. Received at the 8 th International Conference on Alzheimer s Disease and Related Disorders in Stockholm, Sweden, 21 July. 2003 School of Behavioral and Cognitive Neurosciences Groningen New Year s Lecture 2003. Exploring the brain: a search for our selves. 2003 Honorary member of the installation committee of the journal about Gender Identity Disorders, 7

the GID Journal 2004 Hersenstichting Lecture, 3 rd Dutch Endo-Neuro-Psycho Meeting, June 1-4, 2004, Doorwerth. "Sexual differentiation of the human brain". 2005/6 Visiting Professorship in Sleep Medicine at Stanford Medical Center, CA, USA (American Academy of Sleep Medicine and Pfizer Inc.). Selected as one of the 200 Dutch scientists for the Keur der Wetenschap ( Cream of Science ), 10 May 2005 KNAW (www.keurderwetenschap.nl). Honorary editor of Neuroendocrinology Letters. Visiting Professorship in Sleep Medicine (Amer.Ass.of Sleep Med.& Pfizer) at Stanford, CA, USA. Guest Professor at the Beijing Institute of Radiation Medicine from 1 October 2005 to 31 December 2008. 2007 Guest Professor at Zhejiang University, Hang Zhou, PR China. 2008 Academy medal for his role in national and international neuroscience (fundamental to applied), for his initiative to start the Netherlands Brain Bank, and for his research in Alzheimer's disease Two lectures for the opening of the Academic Year on the invitation of Gezondheids- en Levenswetenschappen, Faculty of Aard- en Levenswetenschappen, Vrije Universiteit, Amsterdam. Title: Education and Environment have only a minor effect on us. Most of our characteristics are inborn. Chairman International MS audit of MS Center Rotterdam (27 November) and MS Center Amsterdam, with Prof. J.P. Andel (Canada), Prof. A. Compston (UK) and Prof. J. Kesselring (Switzerland). 2009 The "Prof. Nico Bakker Lezing" van de Nederlandse Vereniging voor Urologie, 14 November, Martini Plaza, Groningen. 2011-14 Chao Kuang Piu Chair of Zhejiang University, Hangzhou, P.R. China Functions and committees Netherlands Institute for Brain Research 1971/1973 Secretary of the NCIBR Institute Council 1976/1977 Member RECON-committee 1977 Leader of research team 'Interaction of the Nervous System and Hormones during Maturation' at the NIBR 1982 Secretary-treasurer of the "Van den Houtenfonds" Foundation for the NIBR 1985 Initiator and director of the Netherlands Brain Bank in the Netherlands Institute for Brain Research 1986 Member board of governors of the 'Stichting tot Ondersteuning van de Hersenbank, beheerd door het Nederlands Instituut voor Hersenonderzoek' 1986 Founding member ALS Brain Bank and member board ALS-Bank foundation 1989 Founding member MS Brain Bank Dutch Societies and Committees 1976/1977 Member of the board of the Dutch Society for Endocrinology 1976/ Secretary of the Netherlands 'International Brain Research Organization' (IBRO) Committee of the Royal Academy of Arts and Sciences 1977/1980 Vice-president of the Dutch Society for Endocrinology 1979/1985 Member committee on 'Teratology of Chemical Compounds' (Health Council, The Hague) 1980/1981 President of the Dutch Society for Endocrinology 1980/1989 Member 'ZWO-dwarsverband' committee of Gerontological Research 1981 Member 'FUNGO-dwarsverband' committee of Gerontology Member committee of the Helffer-Kootkar Prize Foundation 1984/1990 Member committee 'Neurosciences' of FUNGO/Medigon 1985/ Member 'Amsterdamsche Neurologenvereeniging' 1985/ Member 'FUNGO/MEDIGON-dwarsverband' committee on 'Etiology of Aging' 1985/ Chairman committee on the assignment of subsidized aged animals (NWO) 1986/1990 Member NWO/ZWO committee of Neurosciences 1987 Member MEDIGON committee of 'Dementia/Alzheimer's Disease' 1987/2003 Member scientific council Netherlands Organization for Scientific Research of Multiple Sclerosis 8

1989/ Member Policy Committee Neuropathology 1990 Member committee incentive prize 'Amsterdamsche Neurologenvereeniging' 1990 Member committee incentive prize 'Sandoz' 1990/ Member advisory board "Veldwijk" Psychiatric Hospital 1990/2003 Member scientific advisory council of the Netherlands Brain Foundation 1991/1992 Member scientific committee NWO 'The Decade of the Brain'. 1994 Consultant commissie "Wetenschap en Beleid" van de Alzheimer Stichting. 1995/2002 Member Scientific Council Dutch Alzheimer's Foundation 1997/ Chairman of De Arnold Oosterbaan Brain Foundation. 1997-2007 Member of the Program Committee Aging Successfully (Succesvol Ouder Worden), NWO. 1998 Lid Wetenschappelijke Adviesraad Stichting Onderzoek Licht en Gezondheid (TU Eindhoven, Philips). 1999 Lid Raad van Aanbeveling voor de Stichting Medisch Interfacultair Congres t.b.v. het 10e Medisch Interfacultair Congres met als onderwerp Experimentele Geneeskunde, Universiteit Leiden. 1999 Member Health Council Committee Dementia (#655). 2000 Lid Adviesraad Stichting Vrijwillig Leven (Dutch Society for Dignified Voluntary Death) 2000 Lid Hoogleraren Dispuut UvA Unitas Multiplex. 2002 Lid Comité van Aanbeveling van het Nederlands Centrum Hersenletsel 2003 Member Health Council Committee Brain Damage due to Sports (#627) 2008 NVVE, Perspectieven op waardig sterven, werkgroep Dementie (Dying with Dignity workgroup) 2008 Curatorium herbenoeming 3 e vijfjaarstermijn Prof. Dr. H.B.M. Uylings (Morfometrie en ontwikkeling van het zenuwstelsel, Vrije Universiteit Amsterdam) 2008-2009 Medische Adviesraad Science Museum Corpus, Oegstgeest, The Netherlands. 2008/ Member Program Advice Committee, Council for Civilian-Military Care and Research (Ministry of Defence) 2009 Ministerie van Justitie: commissie en adviesrapport De Hersenen in Beeld. Neurobiologisch onderzoek en vraagstukken op het gebied van verklaring, reductie en preventie van criminaliteit. 2009-2010 Member of Civilian Initiative on Completed Life (Burgerinitiatief Voltooid Leven). 2010 Treasurer of the Stichting Vrienden van de Neurofederatie. International Societies and Committees 1978 Charter member of the International Society for Developmental Neurocience (ISDN) 1979/84 Member of the International Scientific Committee of the European Science Foundation, ESF (European training programme in Brain and Behavior Research, ETP, Strasbourg, France) 1983/84 Regional secretary of the International Society for Developmental Neuroscience (ISDN) 1984 Member selection committee for neuroendocrinology posts at the Edinburgh MRC Reproductive Biology Unit 1984/93 Founding member of the Research Group on Dementias of the World Federation of Neurology and member of the Executive Committee. 1984 Coordinator for the Netherlands of the European project on aging (EURAGE) 1985/88 Director of the IBRO Workshop Programme (Paris) 1987/ Member external advisory committee of the Lab for Pregnancy and Newborn Research, Cornell University, Ithaca, NY, USA., Center for Pregnancy and Newborn Research, University of Texas Health Sciences Center Medical School, Dept. Obstetrics and Gynecology-MSC 7836, Dallas, Texas. 1988 Dutch representative in EC working party 'Age-related Health Problems' of the EC Medical and Health Research Programme (EUROMED, Brussels) 1988/89 Chairman EURAGE subgroup on Tissue Banking 1989/97 Member of the International Medical Advisory Board of the International Federation of Multiple Sclerosis Societies 1990/95 Council member European Neuroscience Association (Panel Neuroendocrinology) 1990/ Member scientific advisory board of the Croatian Brain Research Institute 1991/92 Chairman Peter Debye-Prize on 'Aging of the Brain' 1992/ Member 'Interim Steering Group' European Dementia Research Network 1992/ Member Scientific Committee EUROSPES Foundation 1992/ Member advisory board The European Graduate School of Child Neuropsychology - Graduate Programme 9

1992/ Consultant "Molecular Geriatrics" (Chicago, USA) 1993 Committee member "Einrichtung eines Referenzzentrums für neurodegenerative Erkrankungen" (Bonn, Germany) 1993 Member of the New York Academy of Sciences. 1994/2003 Member scientific board International Alzheimer Research. 1994 Member Audit Committee projects PO1 HD 28014-03 ("Ontogeny of fetal behavior; P.L. Dr. P.W. Nathanielsz) and PO1 HD 21350 ("Parturition and fetal primate hypothalamic function; P.L. Dr. P.W. Nathanielsz). October 3-5, 1994, Cornell University, Ithaca, New York, USA. Member advisory board of the Society for Behavioral Neuroendocrinology and member of the journal committee Hormones and Behavior. 1996 Member panel for the 1996 Parker-Davis Award for Alzheimer's disease. New York, USA, 10 February 1996. 1998 Member review committee German Reference Center for Diseases of the Central Nervous System (GRCC) BrainNet and member International Advisory Board of the GRCC 2001 Chairman Scientific advisory and review board for the German Reference Center for Diseases of the Central Nervous System BrainNet. 2002 Member Forensic Sciences Expert Centre 2003 Member of the International Scientific Advisory Board of the Croatian Institute for Brain Research. 2004 Evaluation of the competence networks in medicine. Funding measure of the German Federal Ministry of Education and Research (BMBF). Consultant for the "Alzheimer's Disease Discovery Workshop", September 29-30, 2004, Cambridge, MA, USA. 2005 Member of the External Advisory Board of the Center for Pregnancy and Newborn Research, University of Texas Health Sciences Center, Medical School, Department of Obstetrics and Gynecology, Houston, Texas, USA 2008 Chairman International MS Audit of MS Center Rotterdam (Nov. 27) and MS Center Amsterdam, with Prof. J.P. Andel (Canada), Prof. A. Compston (UK) and Prof. J. Kesselring (Switzerland). 2009 Member of program-advice committee Research (Programma adviescommissie Onderzoek) of the RZO (Raad voor civiel-militaire Zorg en Onderzoek). 2010 Advisory Board Member Study Protocol Effects of sex steroid hormones on human brain function, structure and connectivity. (PI Rupert Lanzenberger). 2012 Member Advisoryl Board of Functional Neurology and New Trends in Neurosciences. UvA/AMC/Free University/KNAW 1979 Member committee Neurobiology (2nd Phase Education, Faculty of Biology) Member committee Neurological Sciences (2nd Phase, Faculty of Medicine) 1979/81 Member committee Childpsychology (UvA) 1982/2007 Founding member and member scientific advisory board of the Graduate School Neurosciences Amsterdam (ONWA) 1984/ Member 'Vaste Doctoraalexamencommissie Vrije Studierichting Medische Biologie' 1985/89 Chairman committee extra-ordinary professorate Clinical Pharmacology 1985/88 Member selection committee professorate Neurosurgery 1986 Founding member workgroup of clinicians and scientists on 'Brain Development and its disturbances', in collaboration with Dr. P.G. Barth 1987 Founding member of the Amsterdam workgroup of clinicians and scientists on 'Aging and Dementia' 1987/ Co-initiator and member of the board of the Amsterdam Neuroscience Network (since 1992 Research Institute Neurosciences Amsterdam) 1987-88 Member selection committee professorate Pharmacology, specifically Neuroendocrinology (Faculty of Medicine, Free University, Amsterdam) 1988/93 Curator chair Inborn and Hereditary Diseases of the Nervous System (UvA) Prof. Dr. P.G. Barth 1988 Member selection committee personal ordinary professorate Neurosurgery (UvA) 1989/02 Member evaluation committee and scientific advisory board Psychosis-project Adolescents clinic, Psychiatric Center AZUA (Dr. D.H. Linszen) 1990/ One of the three coordinators Research Institute for the Neurosciences of the Medical Faculty (UvA) 1990 Member selection committee ordinary professorate Neurology (UvA) 10

1990/ Coordinator new curriculum block XIII (Faculty of Medicine, UvA, together with Dr. J. Stam) 1991/95 Curator chair Gerontopsychiatry Free University, Amsterdam (P. Eikelenboom) 1992/2000 Curator chair Comparative Neurobiology, Free University, Amsterdam 1992/93 chairman selection committee 'Ordinariaat Verloskunde' 1992/2002 Member advisory committee for the integration of the Medical Faculty of the UvA and the Academic Medical Centre 1992 Co-initiator and Board member Graduate School Neurosciences Amsterdam, and member Research Institute for Neurosciences of the Medical Faculty (UvA) 1993/94 Member selection committee chair Neurology, in particular MS. Free University. 1994 Member project team reorganization Netherlands Ophthalmic Institute. 1994-2005 Member of the committee of the Van Leersum Fund (KNAW). 1994 Member of selection committee ordinary professorate Histology and Cell Biology (UvA) 1997/ Acting member Advisory Committee External Research Projects (Advies Commissie Externe Onderzoeksproject) AMC 1998 Member Curatorium chair Immunological aspects of chronic inflammation of the nervous system Prof. Dr. C. Lucas. Free University, Amsterdam. 1999 Member Advisory Committee appointment Professor of Social Psychiatry (AMC) 2000 Member Committee appointment Professor of Neurology, in particular dementias. 2001 Chairman committee MS programme applications. 2008 Curatorium Bijzondere Leerstoel Prof. dr. H.B.M. Uylings 2012 Member Scientific Advisory Board EU project Prenatal exposure to stress and the effect on (aging) of the brain. Chairs held by NIBR members (PhDs of D.F. Swaab are indicated by an *) 1986-1998 M.A. Corner: Extraordinary chair in Developmental Physiology at the Faculty of Mathematics and Natural Sciences of the UvA (Van den Houten-Foundation), September 1 1987-1996 N.E. van den Poll: Extraordinary chair in Comparative Psychobiology of Emotions at the Subfaculty of Psychology of the UvA (Van den Houten-Foundation), November 1 *1991 R.M. Buijs: Prof. of Medicine, Medical Faculty, Univ. of Ottawa, Canada 1991 H.B.M. Uylings: Extraordinary chair in Morphometry and Development of the Nervous System at the faculty of medicine of the Free University, Amsterdam, January 1 1991 I. Kostovic' (Zagreb, Yugoslavia): Spinoza Chair, UvA 1995 W.J. Freeman (Berkeley CA, USA): Spinoza Chair, UvA *1995 G.J. de Vries (Amherst, MA, USA): Professor of the Department of Psychology 1996-1998 D.F. Swaab: Emil Kraepelin Guest Professorship. Max-Planck-Institut für Psychiatrie, Munich, Germany. 1996 M. Mirmiran: Visiting Professor, Dept. of Pediatrics, Div. Neonatal. & Devel. Medicine, Stanford University, USA. 1996-1997 M. Mirmiran: Visiting Professor, Dept. Physiology, Lab. Pregnancy & Newborn Research, Cornell University, Ithaca, USA. *1997 R.M. Buijs. Extraordinary Chair in Neuroendocrinology, Faculty of Biology, UvA *1997 J.N. Zhou. Professor of Neuroscience, Department of Psychiatry and Neuroscience, First Affiliated Hospital of Anhui Medical University, P.R. China. 1998 J. Verhaagen. Extraordinary Chair in Molecular Biology, Faculty of Biology, Free University, Amsterdam 1999 D.F. Swaab, Visiting Professor at Capitol University of Medical Sciences, Beijing, P.R. China *1999 H.P.H. Kremer, Professor in Neurology, Faculty of Medicine, University of Nijmegen. 1999 R.M. Buijs, Visiting Professor at the University of Strasbourg, France 1999 A. Kalsbeek, Visiting Professor at the University of Strasbourg, France *2000 W.A. van Gool, Professor of Neurology, especially the Dementias, UvA *2000 D. Troost, Professor of Neuropathology, AMC, Amsterdam 2001 Prof. dr. F. Holsboer, Spinoza Chair, Amsterdam University Ver. for the Faculty of Medicine of the UvA *2002 Prof. dr. E.J.A. Scherder, Bijzonder Hoogleraar Klinische Neuropsychologie, in het bijzonder het onderzoek naar de diagnostiek en behandeling van neuropsychologische stoornissen van de ouder wordende mens. Vrije Universiteit, Amsterdam, faculteit der Psychologie en Pedagogiek. *2002 Prof. R.Y. Liu, Professor of Internal Medicine, Geriatric Department, First Affiliated Hospital of Anhui Medical University, Hefei, P.R. China 2002 Prof. dr. C.M.A. Pennartz, Special Professor in Cognitive Neurobiology at the UvA. 11

*2003 Prof. dr. W.J.G. Hoogendijk. Professor of Biological Psychiatry at the Free University, Amsterdam *2005 Prof. dr. E. Fliers, Professor of Endocrinology, Neuroendocrinology in particular, at the UvA *2006 Prof. dr. J.A.M. van der Post, Strategic Professor of Obstetrics, at the UvA *2008 T.A. Ishunina. Associate Professor at the Department of Histology, Kursk State Medical University, Russia. *2009 Prof. dr. E.J.W. Van Someren, Special Professor "Humane Hersenactiviteit van Slaap, Rust en Vigilantie", Vrije Universiteit, Amsterdam *2009 Prof. A. Salehi, Clinical Associate Professor, Stanford University Medical Center, CA, USA *2011 P.J. Lucassen. Structural and Functional Neuroanatomy, Faculteit der Natuurwetenschappen, Wiskunde en Informatica, Swammerdam Institute of Life Sciences, Universiteit van Amsterdam *2012 G. Meynen, Special Professor Forensic Psychiatry, University of Tilburg, Stichting Koningsheide *2012 A. Kalsbeek, Professor of Experimental Neuroendocrinology, University of Amsterdam. Member editorial boards 1975/1986 Acta Endocrinologica 1976/1983 Journal of Neural Transmission 1978/1987 Journal of Developmental Physiology 1978/1998 Journal of Neuroscience Methods 1981/1990 Peptides 1982/1986 Molecular and Cellular Endocrinology 1983/1991 Journal of Neurological Sciences 1987/now Neuroendocrinology Letters (Associate Editor as of January 2003) 1987/1992 Journal of Chemical Neuroanatomy 1988/1996 Journal of Neuroendocrinology 1988/1990 Advances in Neurosciences 1988/1992 Neuroendocrinology 1990/now Neurobiology of Aging 1990/now Progress in Brain Research 1991/now Brain Research 1997/now Neuropraxis 1997/2000 Neuroscience News 1999/2000 Inaugural Editorial Board of Brain and Mind 2002/2005 Associate Editor & Editorial Board Member, XX vs XY 2002/now Associate Editor of Neuroendocrinology Letters 2002/now Associate Editor of the Journal of Prenatal and Perinatal Psychology and Medicine. 2006 Deputy Chief Editor of International Journal of Prenatal and Perinatal Psychology and Medicine 2002/now Series Editor of the Handbook of Clinical Neurology series (new third series), Elsevier. 2005/now Field editor for Neuroendocrinology, Springer's "Encyclopedic Reference of Neurosciences" 2006 Editor of Biogenic Amines. 2008 Member of the Founding Editorial Board of the International Journal of Physiology, Pathophysiology and Pharmacology (IJPPP). 2008 Member of the Editorial Board of the International Journal of Physiology, Pathophysiology and Pharmacology (IJPPP) 2010 Editor (together with Gerard Nuovo) of Methods Vol. In Situ Hybridization. Elsevier, Amsterdam. 2011 Member of the Editorial Board of Neuroscience Bulletin, Shanghai, China. Courses 1968/70 Course 'Methods of medical-biological research', Department of Medicine, Leiden 1969/70 Course 'Medical statistics' (H. de Jonge), Nederlands Instituut voor Preventieve Geneeskunde, Leiden 1975 4th Training Course on 'Radioimmunoassay and Radioreceptor Techniques'. National Institutes of Health, Bethesda, Maryland, USA (March 17-21) Ph.D.-Theses Supervisor of Ph.D. projects 1974 W.J. Honnebier: 'The fetal brain in intrauterine growth and parturition, the role of the 12

hypothalamohypophysial systems', (cum laude) 1976 G.J. Boer: 'The role of pituicytes in the rat neurohypophysis; an exploratory investigation using histo- and microchemistry' K. Boer: 'The rat hypothalamo-neurohypophysial system; its involvement in the onset and course of labour' 1977 J. Dogterom: 'The release and presence of vasopressin in plasma and cerebrospinal fluid as measured by radioimmunoassay; studies on vasopressin as a mediator of memory processes in the rat' (in collaboration with the Rudolf Magnus Institute, Utrecht) "Promotor" (supervisor) of Ph.D. Students 1980 1 F.W. van Leeuwen: 'Light and electronmicroscopical immunocytochemical localization of neuropeptides in the rat brain', together with Prof. J. Joosse and Dr. J.G. Streefkerk ('co-promotors'), Free Univ. of Amsterdam (Faculty of Mathematics and Natural Sciences). 2 R.M. Buijs: 'Vasopressin and oxytocin innervation of the rat', together with Prof. D. de Wied ('copromotor') and Dr. F.H. Lopes da Silva ('co-referent'), Univ. of Amsterdam (Faculty of Medicine). R.M. Buijs has become Professor of Neuroendocrinology 1981 3 J.G.M. van Oyen: 'Reactions to novel and aversive stimuli in female and male rats', together with Prof. J.L. Slangen, Univ. of Utrecht (Faculty of Social Sciences). 1982 4 M. Mirmiran; 'Experimental studies on the significance of active (c.q. rem)-sleep for maturation of brain and behavior in the rat', together with Dr. M.A. Corner ('co-promotor') and Prof. M. Jouvet (Univ. of Lyon) ('co-referent'), Univ. of Amsterdam (Faculty of Medicine). 1984 5 M.A. Hofman: 'Towards a general theory of encephalization', together with Dr. H.B.M. Uylings and Dr. M.A. Corner ('co-promotors'), Univ. of Amsterdam (Faculty of Mathematics and Natural Sciences). 1985 6 G.J. de Vries: 'The vasopressinergic innervation of the brain. a target for gonadal hormones', together with Dr. R.M. Buijs, ('co-promotor'), Univ. of Amsterdam (Faculty of Medicine). G.J. de Vries has become Professor in Amherst, Massachusetts 7 C.G. van Eden: 'Postnatal development of the prefrontal cortex in the rat', together with Dr. H.B.M. Uylings ('co-promotor'), Univ. of Amsterdam (Faculty of Mathematics and Natural Sciences) 8 E. Fliers: 'Hypothalamic changes in aging and Alzheimer's disease' (31 Oct.), together with Prof. H. van Crevel, Univ. of Amsterdam (Faculty of Medicine). In 1997 E. Fliers was awarded the Organon Nederland Prize for Thyroid Research. In 2005 E. Fliers was made Professor of Neuroendocrinology 9 H.P. Oosterbaan: 'Amniotic oxytocin and vasopressin in the human and rat. Alterations during pregnancy, parturition and intra-uterine growth retardation' (21 Nov.), together with Prof. P.E. Treffers and Dr. G.J. Boer ('co- promotor'), Univ. of Amsterdam (Faculty of Medicine). 1986 10 F. van Huizen: 'Significance of bioelectric activity for synaptic network formation. A quantitative electronmicroscopic study on rat cerebral cortex cultures' (17 April), together with Dr. H.J. Romijn and Dr. M.A. Corner ('co-promotors'), Univ. of Amsterdam (Faculty of Medicine). 1987 11 J. Kruisbrink: 'Accurel polymer as an implantable new device for rate-controlled delivery of peptides' (21 May), together with Dr. G.J. Boer ('co- promotor'), Univ. of Amsterdam (Faculty of Medicine). 12 W.A. van Gool: 'Aging of the brain: circadian sleep-wakefulness rhythms and environmental influences in the rat' (4 Jun.), together with Prof. H. van Crevel ('promotor') and Dr. M. Mirmiran ('copromotor'), Univ. of Amsterdam (Faculty of Medicine). W.A. van Gool has become Professor of Neurology. 13 E.M. Brenner; 'Functions of the noradrenergic innervation of the rat brain' (4 June), together with Prof. M.A. Corner ('promotor') and Dr. M. Mirmiran ('co-promotor'), Univ. of Amsterdam (Faculty of Medicine). 14 A.R. Caffé: 'Intra- and extrahypothalamic vasopressin systems in the rat and monkey brain' (8 Oct.), together with Dr. F.W. van Leeuwen ('co-promotor'), Univ. of Amsterdam (Faculty of Medicine). 1988 15 F.G.M. Snijdewint: 'Vasopressin and brain development: the brattleboro rat as a model' (1 Sept.), together with Dr. G.J. Boer (co-promotor), Univ. of Amsterdam (Faculty of Medicine). 13

1989 16 A. Kalsbeek : 'The role of dopamine in the development of the rat prefrontal cortex' (27 Jan.), together with Dr. H.B.M. Uylings ('co-promotor'), Univ. of Amsterdam (Faculty of Medicine). This thesis was awarded the 1989 Incentive Prize of the Amsterdam Neurological Society. 17 B.M. de Jong: 'Cultured rat cerebral cortex explants and their application in the study of spect scan radiopharmaceuticals' (June 23), together with Prof. dr. J.B. van der Schoot ('promotor'), dr. J.M. Ruijter ('co-promotor'), Dr. E.A. van Royen ('co-promotor'), Univ. of Amsterdam (Faculty of Medicine). 1990 18 M.L.H.J. Hermes: 'Functional significance of central vasopressin and oxytocin in rodents' (December 14) 'Examinateur' together with Dr. P. Pévet (Directeur de Recherche) and Dr. R.M. Buijs, University of Straatsburg (Lab of Zoology and Embryology); (December 21) 'promotor' together with Dr. R.M. Buijs ('co-promotor'), UvA (Faculty of Medicine) 1991 19 E. Goudsmit: 'Neural activation during aging and in Alzheimer's disease; the role of sex steroids and osmotic stimulation' (February 14), Univ. of Amsterdam (Faculty of Medicine). This thesis was awarded the SANDOZ PRIZE for endocrinology in 1992. 20 F.J.C.M. van Eerdenburg: 'Postnatal development of some nuclei in the pig hypothalamus' (April 11) together with Prof.dr. C.J.G. Wensing (promotor) and Dr. F.W. van Leeuwen (co-promotor), State Univ. Utrecht (Faculty of Veterinary Medicine). 21 G.J.A. Ramakers: 'Development of fetal rat cerebral cortex in primary tissue culture and the role of bioelectric activity' (June 21) together with Prof.dr. M.A. Corner (promotor) and Prof.dr. W.H. Gispen (promotor), UvA (Faculty of Medicine). 1992 22 D. Troost: 'Inflammatory changes in amyotrophic lateral sclerosis; a neuropathologic immunocytochemical study' (February 6) together with Prof. J.M.B.V. de Jong (promotor) and Dr. J.J. Van de Oord (co-promotor), UvA (Faculty of Medicine). D. Troost has become Professor of Neuropathology. 23 B.H.W. Erdtsieck-Ernste: 'ß-adrenoceptors in rat brain development' (March 26) together with Dr. M.G.P. Feenstra (co-promotor), UvA (Faculty of Medicine). 24 H.A. Griffioen: 'Suprachiasmatic nucleus transplants in rats; growth and functional development' (February 19) together with Dr. G.J. Boer (co-promotor), UvA (Faculty of Medicine). 25 J.M. de Brabander: 'Sparing of function following damage to the prefrontal cortex. What can we learn from the developing brain?' (May 21) together with Prof.dr. H.B.M. Uylings (promotor) and Dr. J.P.C. de Bruin and Dr. C.G. van Eden (co-promotores), UvA (Faculty of Medicine). 26 H.P.H. Kremer: 'The lateral hypothalamus in Huntington's, Alzheimer's and Parkinson's disease' (September 24) together with Prof. dr. G.W. Bruyn (promotor) and Dr. R.A.C. Roos (co-promotor), University of Leiden (Faculty of Medicine). H.P.H. Kremer has become Professor of Neurology. 1993 27 M.B.O.M. Honnebier: 'The role of the circadian system during pregnancy and labor in monkey and man' (February 3) together with Prof. P.W. Nathanielsz (promotor) and Dr. M. Mirmiran (co-promotor), UvA. Cum Laude. Dr. Honnebier was also awarded the Organon prize for Endocrinology in 1993, and the Snoo van 't Hoogerhuys prize in 1996. 28 E. Aronica: 'Excitatory amino acids in nerve cell development and neuronal plasticity' (June 1) together with Prof.dr. F. Nicoletti (promotor) and R. Balázs (co-promotor), UvA. Cum Laude. 29 C.J.C. Boersma: 'Neuron-glia interactions in the rat neurohypophysis; the role of opioids, other neuropeptides and their receptors' (November 26) together with Dr. F.W. van Leeuwen (co-promotor), UvA. 1994 30 F.C. Raadsheer: 'Increased activity of hypothalamic corticotropin-releasing hormone neurons in aging, Alzheimer's disease and depression: a study on human postmortem material' (June 13), together with Prof. dr. F.J.H. Tilders (promotor), UvA. 31 M.J.A. van Veldhuizen: 'In vivo noradrenaline overflow in rat brain' (September 13), together with Dr. M.G.P. Feenstra (co-promotor), Univ. of Amsterdam. 32 J.S. Purba: 'The paraventricular nucleus of the human hypothalamus during aging and in several pathologies: a morphometric study on postmortem material'; (September 19), together with Dr. M.A. Hofman (co-promotor), Univ. of Amsterdam. 33 A.M. Resink: 'Trophic and toxic influences of excitatory amino acids in cerebellar granule cell cultures: regulation of N-methyl-D-aspartate receptors'; (December 23), together with Dr. R. Balázs and Dr. G.J. Boer (co-promotors), UvA 14

1995 34 N.J. Hack: 'Excitatory amino acids and the development of cerebellar granule cells in vitro'; (February 9), together with Dr. R. Balázs (co-promotor), UvA 35 E.J.A. Scherder: 'Peripheral nerve stimulation in Alzheimer's disease; Effects on memory and affective behavior'; (May 15), together with Prof. dr. T.L. Holdstock (promotor) and Dr. J.M. Bouma (copromotor), Free University, Amsterdam 36 E.J. Van Zwieten: 'Vasopressin systems in aging and Alzheimer's disease: a study on rat and human brain'; (November 9), together with Dr. R. Ravid (co-promotor), UvA. 37 J.A.P. Van de Nes: 'Independent occurrence of -protein deposits and cytoskeletal changes in the brain of Alzheimer's disease patients: a study in the human hypothalamus with anti-a a nd Alz-50'; (December 6), together with Dr. W. Kamphorst and Dr. C. Jonker (co-promoters). Free University, Amsterdam. 1996 38 P.J. Lucassen: 'The relationship between neuronal activity, brain aging and Alzheimer's disease'. (18 March). UvA. Cum Laude. Dr. Lucassen was also awarded the Organon Prize for Endocrinology 1996. In 2011 he became Professor of Structural and Functional Neuroanatomy. 39 P.A. Piosik: 'Influence of thyroid hormones on gene expression in goat brain during development'. (17 April), together with Prof. Dr. J.J.M. de Vijlder (promotor) en Dr. F. Baas (co-promotor). UvA. 40 J.N. Zhou: Vasoactive intestinal polypeptide in the human hypothalamus. Relationship to development, sex, aging and Alzheimer s disease, rhythmicity and depression. (4 October). UvA. In 1997 The Netherlands Society for Endocrinology awarded this thesis with the Thesis Prize. 41 A. Salehi: Relationship between neuropathological hallmarks and neuronal activity in Alzheimer s disease. A postmortem study on the human hypothalamus and hippocampus. (7 November). UvA. Dr. Salehi was awarded the Boerhaave Aanmoedigingsprijs (Dfl. 10.000) on 20 November 1998. 42 A.J.G.D. Holtmaat: Functional analysis of B-50/GAP-43 in transgenic mice and by viral vectormediated gene transfer. (9 December). University of Utrecht. 1997 43 W. Witting: Aging of the circadian system. Chronobiological effects of light. (15 January). UvA. 44 J.A.M. van der Post: Preeclampsia: relation with vasopressin and activation of thrombocytes. (25 April). UvA. 45 W.T.J.M.C. Hermens: Viral vectors. Towards application in neuroregeneration research. (19 June). University of Utrecht. 46 E.J.W. van Someren: Rest-activity rhythms in aging, Alzheimer s disease and Parkinson s disease. Methodological developments and therapeutic interventions. (4 July). UvA. Cum Laude. E.J.W. van Someren was awarded the Young Investigators Award by the International Society for Chronobiology in 1997. He was made a Special Professor of Human Brain Activity in Sleep, Rest and Vigilance in 2010. 1998 47 B.A.Th.F. Gabreëls: Vasopressin secretion disorders in: Diabetes insipidus, Prader-Willi syndrome, Wolfram syndrome. (16 April). UvA. Dr. Gabreëls was awarded the Organon Prize for Endocrinology 1999. 48 W.J.G. Hoogendijk: Brain changes in depression. A combined clinical and post-mortem study in depressed patients with or without Alzheimer s or Parkinson s disease. (12 June), together with Prof. dr. P. Eikelenboom. Free University, Amsterdam. Dr. Hoogendijk was awarded the Ramaermedaille for Psychiatry on 17 April 1999 and the International Society for Biological Psychiatry Scientific Award for Young Scientists, 3-4 June 1999. 49 J.P. Dai: The anatomical organization of the human hypothalamus in relation to circadian rhythms. Immunocytochemical and postmortem tracing studies. (4 November), together with Prof. Dr. R.M. Buijs, UvA. 1999 50 Lisette van Esseveldt: Transplantation of the rat suprachiasmatic nucleus. Functional studies and ex vivo adenoviral vector-mediated gene transfer. (1 June), together with Prof. Dr. W.J. Rietveld, UvA. 51 Paul Dijkhuizen: Viral vectors as tools for neurotrophin gene delivery to the injured nervous system (21 September), together with Prof. dr. J. Verhaagen en Prof. dr. W.H. Gispen. This thesis was awarded the Greiner Award for best Ph.D. thesis on gene therapy for the year 1999. 2000 52 Jeroen Pasterkamp: Chemorepulsive semaphorins in neural regeneration. (20 June), together with Prof. Dr. J. Verhaagen, Free University, Amsterdam. 53 Simone Lunshof: Circadian rhythms in the normal and growth-retarded fetus and infant (21 June), together with Prof. Dr. O.P. Bleker, UvA. 15

54 Tatjana Ishunina: "Functional sex differences in the human hypothalamus and nucleus basalis of Meynert: relation to ageing and Alzheimer's disease" (Dec. 1) together with Prof. dr. A. Zavialov, UvA. Russian thesis (2003) summa cum laude. 2001 55 R.-Y. Liu: Circadian system rhythm disorders in aging and AD (4 July). UvA. 56 B. Blits: Cell and gene therapy: experimental strategies for spinal cord regeneration (26 February). Free University, Amsterdam 2002 57 T.H.K. Heinen: Timing and functional implications of GABA A receptor maturation during visual cortex development. (19 December). Free University, Amsterdam, together with Prof. dr. A.B. Brussaard 2003 58 W.C.J. Chung: Sexual differentiation of the human and rodent forebrain. (15 January). UvA, together with Prof. dr. G.J. de Vries. 59 M.J. Ruitenberg: Experimental spinal cord injury. Emerging cell and gene therapeutic strategies for neuroregeneration. (22 May). Free University, Amsterdam, together with Prof. J. Verhaagen. 2004 60 Z.A. Erkut: The stress-axis in multiple sclerosis. Effects of sepsis, morphine and corticosteroids. (11 mei). UvA. 61 F. de Winter: Secreted semaphorins: chemorepulsive control of neural regeneration? (27 mei). Free University, Amsterdam, together with Prof. J. Verhaagen. 62 F.P.M. Kruijver: "Sex in the brain. Gender differences in the human hypothalamus and adjacent areas. Relationship to transsexualism, sexual orientation, sex hormone receptors and endocrine status". (22 October). UvA, together with Prof.dr. L.J.G. Gooren. Won the GIRES research award 2004. 63 J. de Wit: "Truncated TrKB and semaphorin 3A: a role in restricting structural plasticity in the adult nervous system?" (29 November). Free University, Amsterdam, together with Prof. dr. J. Verhaagen. 2005 64 F. de Vrij: "Mutant ubiquitin and the proteasome in Alzheimer's disease" (10 February). UvA, together with Prof. dr. J. Verhaagen 65 A. Alkemade: "Central components of the human hypothalamus-pituitary-thyroid axis and their role in nonthyroidal illness" (27 September). UvA, together with Prof. dr. W. Wiersinga and Prof. dr. E. Fliers. 66 M.W. Luijpen: "Transcutaneous electrical nerve stimulation in mild cognitive impairment." (8 December) Vrije Universiteit, Amsterdam, together with Prof. dr. E.J.A. Scherder. 2007 67 Y. Wu: The human circadian timing system in aging, Alzheimer s disease and depression (30 January). UvA, together with Prof.dr. J.N. Zhou. 68 G. Meynen: "Neurobiological characteristics of depression" (22 May). Vrije Universiteit, Amsterdam, together with Prof. dr. W.J.G. Hoogendijk. 69 R. Riemersma-Van der Lek: "Keep it bright. Deterioration and reactivation of the biological clock in dementia" (5 July). UvA. 70 L. Eggermont: "Neurorehabilitation in dementia on the move. Influences of physical activity on cognition, mood, and the rest-activity rhythm" (21 December). Vrije Universiteit Amsterdam, together with Prof. E.J.A. Scherder. 2008 71 R. Fronczek: "Hypocretin deficiency. Neuronal loss and functional consequences" (30 January). Universiteit Leiden, together with Prof. dr. J.G. van Dijk. 72 P. van Tijn: "The effect of mutant ubiquitin on proteasome function in relation to neurodegenerative disease" (7 November). UvA. 73 N. Koning: "Imbalanced immunity in multiple sclerosis" (12 March). UvA, together with Prof. Dr. R.A.W. van Lier. 2009 74 C.A.M. Bossers: "Spot the difference. Microarray analysis of gene expression changes in Alzheimer's and Parkinson's disease." (10 November). Vrije Universiteit Amsterdam, together with Prof. Dr. J. Verhaagen and Prof. Dr. C.G. Kruse. 2010 75 E. Altena: "Mapping insomnia: brain structure, function and sleep intervention", together with Prof. dr. E.J.W. van Someren, Dr. Y.D. van der Werf, Prof.dr. Ph. Scheltens. 76 J. Middeldorp: "Astrocytes in development, aging and disease", together with Dr. E. Hol, copromotor. 2011 77 S. van den Berge: The endogenous repair capacity of the Parkinson brain, together with Prof. Dr. 16

E. Hol. "Co-promotor" (co-supervisor) of Ph.D. Students 1985 W. Kamphorst: 'Glial cells. An immunocytochemical and morphological study', together with Prof. F.C. Stam (promotor) and Prof. E.J. Essels (referent), Free Univ., Amsterdam (Faculty of Medicine). 1996 M.J.Th. Koenderink: 'Postnatal neuronal maturation of the human prefrontal cortex'; (February 6) Together with Prof. Dr. H.B.M. Uylings (promotor) and Prof. A. Ruiz Marcos (referent) Free University, Amsterdam (Faculty of Medicine). 1991 O. Van Reeth (Brussels, Belgium) "Manipulation pharmacologique et comportementale de l'horloge circadienne des mammifères". "(Co-)referent" / "External Referent" of Ph.D. Theses 1979 J. Assies: 'Neuroendocrine aspects of prolactinomas. a clinical study', Univ. of Amsterdam (Faculty of Medicine). 1981 M.J. van der Horn: 'De radioimmunologische bepaling van vasopressine in urine', Univ. of Amsterdam (Faculty of Medicine). 1984 L.P.C. Schot: 'Immunocytochemical studies on peptidergic neurons in the pond snail lymnaea stagnalis', Free Univ., Amsterdam (Faculty of Mathematics and Natural Sciences). 1990 J.M. Rozemüller-Kwakkel: 'Amyloid Formation in Alzheimer's Disease. An immunocytochemical study' (19 Jan.) Free Univ., Amsterdam (Faculty of Medicine). 1990 M. Najimi (Lyon, France) on the development of the hypothalamus and SIDS 1992 I. Huitinga: 'The role of macrophages in the pathogenesis of experimental allergic encephalomyelitis' (13 Nov.) Free Univ., Amsterdam (Faculty of Medicine). 2003 S. Overeem: Narcolepsy. From clinical entity to hypocretin deficiency (28 May) University of Leiden (Faculty of Medicine). 2004 S. Perreau-Lenz: Control of the daily melatonin rhythm. (9 June). UvA (Faculty of Medicine). Rapporteur externe.. Ph.D. Committee member 1978 A.F.M. Moorman: 'Synthesis of mythochondrial proteins - identification and localization of genes on yeast mitochondrial DNA', Univ. of Amsterdam (Faculty of Mathematics and Natural Sciences). 1979 O.P. Bleker: 'On human intrauterine growth', Univ. of Amsterdam (Faculty of Medicine). A. ter Maat: 'Integrative properties of a group of neuro-endocrine cells in the pond snail', Univ. of Amsterdam (Faculty of Mathematics and Natural Sciences). 1980 W.L. Lamers: 'Multihormonal control of enzyme clusters in liver ontogeny', Univ. of Amsterdam (Faculty of Medicine). C.W. Pool: 'An immune- and enzyme-histochemical determination of striated muscle fibre characteristics', Univ. of Amsterdam (Faculty of Mathematics and Natural Sciences). 1981 M.F. Schutte: 'Over de behandeling van dreigende vroeggeboorte', Univ. of Amsterdam (Faculty of Medicine). P.W.J. Peters: 'Induced congenital malformations of the central nervous system. a teratological study', Univ. of Utrecht (Faculty of Medicine). 1982 H.J.L.A. Ruis: 'Borstvoeding. in het bijzonder over het afkolven van moedermelk', Cath. Univ. of Nijmegen (Faculty of Medicine). H.W.M. Steinbusch: 'Serotonergic neurons in the central nervous system of the rat', Cath. Univ. of Nijmegen (Faculty of Medicine). G. Schmitt-Ehret: 'Les cellules opiocortico-melanotropes du lobe intermediaire de l'hypophyse. etude au cours de l'ontogenese et apres perturbations du metabolisme hydromineral chez la souris', Strasbourg, Univ. Louis Pasteur (Faculty of Mathematics and Natural Sciences). 1985 J. Overweg: 'Withdrawal of antiepileptic drugs seizure-free adult patients. Prediction of outcome', Univ. of Amsterdam (Faculty of Medicine), 24 October. P. Room: 'Connections of the parahippocampal cortex. A neuroanatomical tracing study in the cat', Free Univ. of Amsterdam (Faculty of Medicine), 25 October. J.A. Poulis: 'Circadian urinary excretion rhythms in rats', Univ. of Leyden (Faculty of Medicine), 4 December. 1986 F.H. de Jonge: 'Sexual and agressive behavior in female rats. Psychological and endocrine factors', Univ. of Utrecht (Faculty of Social Sciences), 14 February. 1987 L.J.A. van Putten: 'The prolactin cells and plasma prolactin levels in the aging rat: an immunocytochemical and biochemical study', Univ. Nijmegen (Faculty of Mathematics and Natural 17

Sciences), 3 December. 1988 N.E.P. Deutz: 'Pathological aspects of acute hepatic encephalopathy in the rat. An electroencephalographic, biochemical and in vivo brain NMR spectroscopic study', Univ. of Amsterdam (Faculty of Medicine), 10 March. B.T. Poll-The: 'Genetic Peroxisomal disorders', Univ. of Amsterdam (Faculty of Medicine), 6 October. 1989 F.T.M. Rotteveel: 'Clonal analysis of human lymphocyte functions: implications for the study of the immunopathology of multiple sclerosis', Univ. of Amsterdam (Faculty of Medicine), 9 February. J.M.H.H. van Hest: 'Behavorial differences between male and female rats: learning and memory', Univ. of Amsterdam (Faculty of Psychology), 9 May. E. Mullaart: 'DNA damage and repair in relation to aging', University of Leiden (Faculty of Mathematics and Natural Sciences), 13 September J. Scholtens: 'Behavioral consequences of agonistic experiences in S3 rats', 1 December. 1990 T.A.M. Voorhuis: 'Vasotocin in the canary brain', University of Utrecht (Faculty of Medicine), 29 March R.P.W. Heinsbroek: 'Sex differences in behavioral and biochemical consequences of aversive stimulation', Univ. of Amsterdam, Faculty of Mathematics and Natural Sciences, 31 May. 1992 C.M. Van Duijn: 'Risk factors for Alzheimer's disease; a genetic epidemiologic study'. Erasmus Univ. Rotterdam, Faculty of Medicine, January 29 C.J.A. de Groot: 'Characterization and function of brain macrophages and neuroglial cells'. Free University, Amsterdam, Faculty of Medicine, 15 May J.A. Gorter: 'Chronic neonatal neurotransmitter interference and adult brain function: effects of clonidine and MK-801'. UvA, Faculty of Medicine, 4 June P.A.E. Sillevis Smitt: 'Amyotrophic lateral sclerosis. Experimental Animal, Immunocytochemical and Biochemical Studies'. Univ. of Amsterdam, Faculty of Medicine, 30 June D. Terwel: 'Vasopressin in the brain and plasma of the aging rat. A radioimmunoassay study'. University of Maastricht, Faculties II, 5 November 1993 D. Jaarsma: Glutamate and related substances in the brain: histochemical methodology and Alzheimer's pathology. University of Groningen, Faculty of Medicine, 31 March N.P.L.G. Verhoeff: Neuroreceptor ligand imaging by Single Photon Emission Computerised Tomography (SPECT). UvA, Faculty of Medicine, 1 April. Cum Laude. M.M.B. Breteler: Cognitive decline in the elderly. Erasmus University Rotterdam, Faculty of Medicine, 18 June. R. Adriaanse: Pulsatile and circadian TSH release in health and disease. UvA, Faculty of medicine, 1 July. M.P. van Veen: Dynamic mechanisms of neuronal outgrowth. Free University, Faculty of Medicine, 1 September. S.A. Scherjon: The brainsparing effect: flow velocity waveforms in the fetal and neonatal period and their relation to intracranial pathology and neurological outcome. UvA, Faculty of Medicine, 19 October. D.H. Linszen: Recent onset schizophrenic disorders: outcome, prognosis and treatment. UvA, 16 November. 1994 A.J.W. van der Does: Symptomatology and cognition in recent onset schizophrenia. UvA, 20 January. E.M. van der Beek: Circadian regulation of the hypothalamus-pituitary-gonadal axis in the female rat. University of Utrecht, 22 February. A.M.W. van Dam: Production and action of immunomodulators in the rat brain. Free UvA, 25 November. J. Bauer: Macrophages and glial cells in the pathogenesis of experimental autoimmune encephalomyelitis. UvA, 2 December. R.H.M. Hermans: Behavioural sequelae of perinatal hypoxia in the rat. University of Maastricht, 21 October. M.H. Godfried: Soluble receptors for tumour necrosis factor in HIV infection. UvA, 23 December. 1995 R.L.A.W. Bleys: Innervation of the basal cerebral arteries: pathways and densities. University of Utrecht, 28 February. K. Gerritse: Antibody formation and immunomodulation in experimental allergic encephalomyelitis and multiple sclerosis. Erasmus University of Rotterdam, 28 September. A.P. Evans: Somatic mutations in vasopressin neurons. Identification of mutant transcripts and precursors. University of Utrecht, 3 October. 1996 J. Bakker: Sexual differentiation of the brain and partner preference in the male rat. Erasmus University Rotterdam, 6 March. J.B. Derks: The effects of antenatal glucocorticoid administration on the fetus. University of Utrecht, 31 May. W. Hesen: Corticosteroid receptor mediated modulation of serotonergic and cholinergic responsiveness 18

in rat hippocampal CA1 neurons. UvA, 13 September. A.B. Dessens: Prenatal exposure to phenobarbital and diphantoin. A study on long-lasting consequences. UvA, 18 September. 1998 B.M.J. Uitdehaag: Cytokines and glucocorticoids in experimental allergic encephalomyelitis and multiple sclerosis. Free University, Amsterdam, 9 January. I. Dijksta: Glucocorticoids and adaptive changes in the hypothalamic-pituitary-adrenal system. Free University, Amsterdam, 18 February. L. Heijink: Hexanedione toxicity and neurofilament metabolism. UvA, 22 April. G. Kwakkel: Dynamics in functional recovery after stroke. Vrije Universiteit, Amsterdam, 2 December. M. van Stipdonk: The immune response to -crystallin: self, non-self and phosphorylation. UvA, 17 March 1999 Y.G.H. Maas: Early neurological development, growth and nutrition in very preterm infants. UvA, 11 November. 2001 I.F. Palm: Timing of female reproduction. Role of the suprachiasmatic nucleus. UvA, 13 March. J. Lavalaye: SPECT imaging in young patients with schizophrenia. UvA, 25 April. J. Ratsma: Biological vulnerability to alcoholism in children of alcoholics. UvA, 30 November L. Reneman: Investigating the potential neurotoxicity of ecstacy (MDMA). An imaging approach. UvA, 6 December. (cum laude) J. Grootendorst: Stress effects on cognitive performance of apolipoprotein E knockout mice. University of Leiden, 13 June. 2002 L.J.S. Brokken: The TSH receptor in the pituitary and its clinical relevance. UvA, 14 May. 2002 T. Rinne: The Neuro-endocrine scars of sustained childhood abuse in adult female patients with borderline personality disorder. UvA, 28 May. 2002 M. Kromkamp: Homeobox genes and thalamic pathology in schizophrenia. A postmortem study. University of Utrecht, 17 October. 2003 R.C. Sival: Aggressive behaviour in dementia. University of Utrecht, 18 November. 2004 N.D. Prins: Cerebral Small Vessel Disease in Dementia and Depression. Erasmus University Rotterdam, 24 March. V.M. Heine: Adult hippocampal cell birth and death in relation to stress, aging and the vasculature. UvA, 28 September. I. van Welie: Activity-dependent plasticity of neuronal excitability. A role for short-term modulation of voltage-gated ion channels in neuronal function. UvA, 30 November. Swaab added to promotion committee due to request for Cum Laude. 2005 K.R.A. van Dijk: Peripheral electrical nerve stimulation in Alzheimer's disease. Vrije Universiteit, Amsterdam, 6 September. F. Kreier: Autonomic nervous control of white adipose tissue. UvA, 7 September. J.P. Brouwer: Thyroid and adrenal axes in major depression. UvA, 18 October. R.J.L. Lindauer: Effects of psychotherapy on the biology of posttraumatic stress disorder: brain imaging and neurophysiological correlates. UvA, 16 December. 2006 F.J. Stam: Exploring the regenerative response to peripheral nervous system injury: a genomics and proteomics approach. Vrije Universiteit, Amsterdam, 29 May. K. Boekhoorn: Microtubule associated proteins and plasticity in the developing and diseased brain. University of Amsterdam, 26 September. 2007 S.R. de Rooij: Metabolic consequences of prenatal exposure to the Dutch famine. UvA, 8 February. J.M. Oosterman: Aging matters. White matter and age-related conditions: a focus on cognition, pain, and the rest-activity rhythm. 2008 W.T.J.H. Hendriks: Gene therapy for neurotrophic factors in experimental neurotrauma. Vrije Universiteit Amsterdam, 20 June. M.R. Tannemaat: Molecular nerve repair. Vrije Universiteit Amsterdam, 3 December E.H.P. Franssen: Olfactory ensheathing glia as a source of neuroregeneration-promoting molecules. Vrije Universiteit Amsterdam, 5 December 2009 T.E. Hartog: Singing on steroids. A story of neuronal plasticity and blood vessels. Vrije Universiteit Amsterdam, 2 September. F.M.J. Jacobs: Pitx3 and Nurr1 in control of terminal differentiation of Meso-diencephalic dopamine neurons. Universiteit Utrecht, 3 September 2010 N.A. Aziz: Huntington's disease. Hypothalamic, endocrine and metabolic aspects. Universiteit Leiden, 31 maart. 2011 T.T. Vo: Studies on semaphorin 3A in the neuromuscular junction and in perineuronal nets. Vrije Universiteit, 8 September 2011 19

M. Sinnema: Prader-Willi syndrome: genotype and phenotype at adult age. University of Maastricht, 9 December 2011. 2012 A.F.M. van Abeelen: Undernutrition and chronic disease. The 1944-1945 Dutch famine. University of Amsterdam, 15 June 2012. International conferences organized (* = post-academic teaching) 1973* 8th International Summer School of Brain Research, 'Integrative Hypothalamic Activity' (The role of the hypothalamus in development, reproduction, growth and behavior), together with Dr. J.P. Schadé, Baarn, June 25-29. 1974 Symposium, 'Brain Development and Thyroid Deficiency', together with Prof. A. Querido (Leyden), Royal Academy, Amsterdam. 1975* 9th International Summer School of Brain Research, 'Perspectives in Brain Research', together with Dr. M.A. Corner, Amsterdam, July 28 - August 1. Member local committee of the Xth Acta Endocrinologica Congress, Amsterdam. 1976 Symposium, 'Melanocyte Stimulating Hormone: Control, Chemistry and Effects', together with Prof. P.G. Smelik and Dr. F.J.H. Tilders, Free Univ., Amsterdam, July 14-16. 1977* 10th International Summer School of Brain Research, 'Maturation of the Nervous System', together with Drs. M.A. Corner, H.B.M. Uylings and N.E. van de Poll and Ir. K. Kuijpers, Amsterdam, July 11-15. 1980* EMBO Practical Course, 'Immunocytochemistry and its Application in Brain Research', together with Dr. G.J. Boer et al., Amsterdam, May 27-30. 1981* 12th International Summer School of Brain Research, 'Chemical Transmission in the Brain. The Role of Amines, Aminoacids and Peptides', together with Drs. R.M. Buijs and P. Pévet, Amsterdam, August 31 - September 4. 1982* Second EMBO Practical Course, 'Immunocytochemistry and its Application in Brain Research', together with Drs. F.W. van Leeuwen and R.M. Buijs, Amsterdam, May 24-28. Member Program-committee 3rd International Meeting of the International Society for Developmental Neurosciences (ISDN), Patras, Greece. 1982/83 Advisory member Program committee Symposium, 'Aging, Dementia and Memory', Cath. Univ. of Nijmegen. 1983* 13th International Summer School of Brain Research, 'Sex Differences in the Brain. Relation between Structure and Function', together with Dr. J.P.C. de Bruin, Dr. H.H. Swanson, G.J. de Vries and J. Sels. 1984* ETP Winter School 'New Developments in the Investigation of the Human Brain', together with Prof. G. Berluchi (Pisa, Italy) and T. Crow (London, U.K.), Zuoz, Switzerland, January 7-14. 1983/84 Member local Committee European Neuroscience Association (ENA), meeting The Hague, September 11-15. 1985* Co-organizer Practical Course on Morphometry and Stereology in Neurosciences, Amsterdam, May 20-24. 1985* 14th International Summer School of Brain Research, 'Aging of the Brain and Senile Dementia', together with E. Fliers, W.A. van Gool, F.P.A.J. van Haaren and M. Mirmiran, Amsterdam, August 26-30. 1986 Member Scientific committee 3rd International Symposium 'Trace Elements and Health', Free Univ., Amsterdam, September 5-6. 1987 Member organizing committee of the International Symposium on Alzheimer's Disease, Free Univ., Amsterdam, May 7-9. 1987* 15th International Summer School of Brain Research, 'Neurochemistry of Functional Neuroteratology; permanent Effects of Chemicals on the Developing Brain', together with G.J. Boer, M.G.P. Feenstra, M. Mirmiran and F. van Haaren, Amsterdam, August 31-September 4. 1988 XIXth Congress of the ISPNE Annual Meeting, together with B. Bohus, University of Groningen, August 21-25. 1990 British-Dutch MS-meeting in NIBR, Amsterdam, 16 March. 1990 Second International Conference on Alzheimer's Disease & related disorders. 15-20 July, Toronto, Canada. 1991* 17th International Summer School of Brain Research, 'The human hypothalamus in health and disease', together with F.W. van Leeuwen, M. Mirmiran, R. Ravid, Amsterdam, 26-30 August 1991. 1991 Member of committee of recommendation for the Alzheimer's Disease International (ADI) Congress 1991. 1992 Member Scientific Committe Third International Conference on Alzheimer's Disease & related disorders. Padua, Italy. 20

1992 Member of the Scientific Committee 'Decade of the Brain' KNAW, Amsterdam, 6-8 December 1992 1993 European Brain Banking in the Decade of the Brain, 19-21 March, 1993, Amsterdam. 1994 Member International Scientific Advisory Committee for the Fourth International Conference on Alzheimer's Disease & Related Disorders (Minneapolis, USA). 1995 ENA Technical Workshop on Brain Banking: the use of human brain material for fundamental and strategic research. 3-7 September, Amsterdam. 1995 Member of the International Scientific Advisory Committee for the Fifth International Conference on Alzheimer's Disease and Related Disorders. Osaka, Japan, 24-29 July 1995. 1996 Member Scientific Organization "Frontiers in maternal, fetal and neonatal health and disease". Cornell Univ., Ithaca, USA, August 9-12, 1996. 1996* Amsterdam International Summer School (AMC) on Alzheimer's disease and other dementias. Diagnosis, treatment and research. July 22-August 9, Amsterdam. 1996 Normal and Pathological Aging, organized with Prof. Dr. F. Holsboer, Munich, Germany, 22 November 1996. 1998 Executive Convener for the Sixth International Conference on Alzheimer's Disease & Related Disorders (Amsterdam) (3000 participants), including a 1) opening presentation; 2) plenary lecture; 3) public education forum; 4) workshop non-pharmacological therapies. 1999 Symposium on the occasion of the NIBR s 90 th anniversary, 8 June 1999. 2000 Chairperson of symposium on cognitive neuroscience in the honour of Patricia Goldman-Rakic. Cortical Dynamics, 28 March 2000 2001* 21 st International Summer School of Brain Research Plasticity in the Adult Brain. Amsterdam, 20-24 August 2001. 2001* The Amsterdam International Medical Summer School, 12 th Edition. Bridging Neurology & Psychiatry on Dementia, Depression, Schizophrenia and Addiction, Amsterdam, 15-20 July 2001. 2001* Spinoza meeting, Association of the UvA, 25/26/27 April 2001 Spinoza lecture Prof. Dr. Florian Holsboer (Max-Planck, Munich, Germany) From neuroendocrine studies in depression to novel therapies. 26 April 2001 Masterclass Prof. dr. Florian Holsboer, 27 April 2001. Chairman Program Committee The Amsterdam International Medical Summer School Bridging Neurology & Psychiatry. Amsterdam, 15-28 July 2001. Member of Organizing Committee 22 nd International Summer School of Brain Research, Amsterdam, 20-24 August 2001. Course of Neuro- and Molecular biology. Minggu, Indonesia, together with Jan Purba, 4 November 2001. 2002 Scientific committee Alzheimer Europe Congres, Commitment to Care. Maastricht, the Netherlands, June 1-4, 2002 2003 Mechanisms Resulting in Sexual Differentiation of the Brain. Netherlands Institute for Brain Research, Amsterdam, 16 January 2003 2004 Member scientific committee Prader-Willi syndrome conference, Christchurch, New Zealand, April 9-12, 2004 Minisymposium The hypothalamus and (critical) illness. Netherlands Institute for Brain Research, December 14, 2004. 2005 Amsterdam-China symposium, 10-12 October, Amsterdam Medical Center (AMC), Amsterdam. Masterclass Neurosciences in het kader van het Amsterdam-China symposium. 11 October, Amsterdam Medical Center (AMC), Amsterdam. Studiemiddag Prader-Willi syndroom. Genen, hersenen, gedrag. 25 November, Netherlands Institute for Brain Research, Amsterdam, together with Prof. dr. L.M.G. Curfs. 24th International Summer School of Brain Research, Hypothalamic Integration of Energy Metabolism, 29 August - 1 September, Amsterdam 2007 Second Joint Meeting of the European PWS Research Group, 23-25 September, Amsterdam. 2008 25 th International Summer School of Brain Research. Neurotherapy: Progress in Restorative Neuroscience & Neurology. 25-28 August, Amsterdam. 2009 The Amsterdam International Medical Summer School 2009: Exploring the brain: from function to dysfunction. 5-31 July, AMC/NIN, Amsterdam. Dutch meetings organized 1973 FUNGO Workgroup, 'Regulation of the hypophysial functions', working visit at the NCIBR, November 15. 1974 Foundation of the workgroup 'Endocrinology', together with Drs. J.L. Touber and W.J. 21

Honnebier.1977Post-academic education course, 'Neuroendocrinology' at the NIBR, Amsterdam, August 8-12. 1978 Didactic symposium, 'Immuno-histochemical localization of hormones', together with Dr. J.G. Streefkerk, Erasmus Univ., Dutch Fed. Meeting, Rotterdam, March 31. 1980 Co-operation Forum 'Hersenwerk', Dienst Wetenschapsvoorlichting, KNAW, Utrecht, November 5. 1983 Workshop, 'Dementia Research' for the Stichting Onderzoek op het terrein van de Ouder wordende Mens (SOOM), together with E. Fliers and W. Chen-Pelt, Amsterdam, October 17. 1984 Meeting "Amsterdamsche Neurologenvereeniging", together with Dr. W. van Emde-Boas, Amsterdam (NIBR), December 6. 1989 Meeting "Amsterdamsche Neurologenvereeniging", together with Dr. A. Hijdra and Dr. F.E. Postumus- Meyer, Amsterdam, December 14. 1990 "Ontwikkeling en veroudering van de hersenen" at the "Nederlands Natuur- en Geneeskundig Congres", Academic Medical Centre, Amsterdam, January 25. 1994 Annual Meeting of the Graduate School Neurosciences Amsterdam: Geheugenprocessen en dementie. Amsterdam, 31 October. 1997 Round table conference Prader Willi syndrome: wetenschappelijke stand van zaken en prioriteiten (together with Dr. H.M. Evenhuis (Zwammerdam) NIH, Amsterdam, March 14. 1999 Recommending Committee of the Stichting Medisch Interfacultair Congres, Leiden, 4 March 1999. 2006 Lid van de Raad van Advies voor 'Het brein ontrafeld', 16 e Medische Interfacultaire Congres. Congrescentrum TU Delft, 4 March 2006. 2007 Spinoza Lecture Jill Goldstein, AMC, Amsterdam, 27 March 2007. Sex differences in the brain: implications for understanding the neurobiology of sex differences in psychiatric disorders. Masterclass Jill Goldstein, NIN, Amsterdam, 27 March 2007 Visit of Jill Goldstein to the F.C. Donders Institute, Nijmegen. Formal Donders lecture: Gonadal hormones & the brain: Implications for understanding sex differences in cognitive and affective functioning. 2008 25 th International Summer School of Brain Research: Neurotherapy. Progress in Restorative Neuroscience and Neurology, 25-28 August, Amsterdam. 2010 Uitburgeringscursus 'Doodgewoon' (ter gelegenheid van het afscheid als hoogleraar van UvA/AMC), Collegezaal 1, AMC, Amsterdam, 17 juni 2010. 2011 AMC Alumni visit to the NIN, 26 March 2011 Some work visits abroad 1970 Dept. of Pharmacology, Univ. of Bristol, Bristol, UK, on request of Prof. H. Heller, May. 1972 Dept. of Anatomy (head: Prof. B.A. Cross), Univ. of Bristol, Bristol, UK, September. 1973 Dept. of Physiology, Univ. of Cambridge, Cambridge, UK, on request of Dr. P.W. Nathanielsz, February March. 1975 Dept. Endocrinology (Dr. P. Czernichow), Hopital des Enfants Malades, Paris, France, April 16. Medical Research Council Developmental Biology Unit, (head: Dr. R. Balàzs), Carshalton, Surrey, UK, May 17. 1976 Dept. of Physiology (Dr. J.F. Morris) and Dept. of Anatomy (Dr. D.F. Salaman), Univ. of Bristol, Bristol, UK, September. 1977 Lab. of Embryology and Comparative Histology (head: Prof. K. Dierickx), Univ. of Gent, Gent, Belgium, March 10-12. Groupe de Neuroendocrinology cellulaire (Dr. A. Tixier-Vidal), Collège de France, Paris, France, November 28. 1981 Dept. of Zoology (Dr. M. Castel), Hebrew Univ. of Jerusalem, Israel, August 12. Dept. of Psychology (Dr. G. Schmitt), Univ. of Strasbourg, Strasbourg, France, November 2-4. 1982 Sarah Herzog Psychiatric Hospital (Dr. H. Belmaker), Jerusalem, Israel, January 30. Univ. of Tel-Aviv (Prof. M.A. Klingberg), Tel-Aviv, Israel, January 31 to February 1. Sandoz AG medizinische Grundlagenforschung (Prof. W. Meier-Ruge et al.), Basel, Switzerland, 22-3. Inst. of Physiol. (Prof. P. Richard et al.), Strasbourg, France, May 4 The Weizmann Institute of Science, Rehovot, Israel, June 23. 1983 Dept. of Human Physiology (Prof. P. Strata), Univ. of Torino, and Lombrosa Collection (Prof. Portioliatti), Torino, Italy, November. 1984 Inst. Louis Pasteur (Dr. P. Pévet), Univ. of Strasbourg, Strasbourg, France, April 24. Dept. of Reproductive Physiology (Prof. Dr. P.W. Nathanielsz and Drs. A. Bass, R. Butler, J. Cummings, B. Currie, T. Devoogd, L. Freeman, B. Hansel, D. Noden, R. Poore, B. Summers), New York State College of Veterinary Medicine, Cornell Univ., Ithaca, New York, May 31 - June 6. 22

Shriver Center for Mental Retardation (Drs. R. Williams, R.D. Adams, V. Caviness and collaborators), Boston, USA, June 6-8. Dept. of Neurology (Drs. M. Di Figlia, M. Flint Beal, M. Massurec, W.J. Schwartz), Massachusetts Gen. Hospital, Harvard Medical School, Boston, USA, June 7. 1985 Prof. G. Dörner, Institute of Experimental Endocrinology, Humboldt University Medical School (Charité), Berlin, GDR, September 11. Dept. of Neurobiology and Anatomy and Center for Brain Research (Drs. P.D. Coleman, C.D. Sladek, W. Silverman, R.Watson, G. Hofman, D.M. Gash, E. Nordeen, K. Nordeen, C. Kellogg, P. Rodier, M. del Cerro, T. Collier, R. Glough, C. Phelps, S. Wiegand, S. Harber and R.M. Herndon), Univ. of Rochester, NY, USA, October. 1987 The Rockefeller Univ., NY, USA (Drs. B. McEwen, R.E. Brinton, V.N. Luine) Inst. for Basic Research on Developmental Disabilities, Staten Island, New York, USA (Drs. H.M. Wisniewski, I. Iqbal and I.Grundke-Iqbal) Laboratory for Pregnancy and Newborn, Cornell, Ithaca, NY, USA (Drs. J. Figueroa, T. Myers, W. Hansel, K. Houpt, B. Honnebier, P.W. Nathanielsz, T. McDonald, B.J. Strupp and T. De Voogd) 1989 Brain Bank of Prof. W.W. Tourtellotte, Los Angeles, California, USA, April 25 Prof. A. Seiger, Prof. B. Wingblad and Dr. I. Alafuzoff, Dept. of Geriatric Medicine, Huddinge Hospital, Stockholm, Sweden, 15 December 1989 1990 Prof. L. Renaud, Fac. Medicine, University of Ottawa, Canada; Dr. Pierre Bois, Pres. MRC; Dr. J. Seely, Dean of Medicine; Dr. T. Pickton, acting chairman, Dept. of Medicine; Dr. D. Grimes, Senior Vice President Research and Administration. Ottawa, 18 July. 1992 Dr. Martha Gillette, Dept. of Cell and Structural Biology, University of Illinois at Urbana/Champaign, USA, 4/5 May Drs. J. Hutchison, J. Biknell, R. Dyer, Prof. I. Hughes, Drs. A. Dickson and C. Wischik, MRC, Cambridge, UK. 18-19 November 1992. 1997 Prof. A. Wirz-Justice, Dept. Psychiatry of the University of Basel, Switzerland, November 1998. Roche, Basel, Switzerland, November 1998 1998 Anhui Medical University and University of Science and Technology, Hefei, Anhui, PR China, September 1998 1998 Xuanwu Hospital, Key laboratories for brain aging (neurology), Military Institute of Medical Sciences, Beijing, PR China, 11-17 November 1998. 1999 Xuan-Wu Hospital, Capital University of Medical Sciences, Beijing, P.R. China (Guest Professor) 14 and 15 October 1999. First Affiliated Hospital of Anhui Medical University, Hefei, Anhui, P.R. China (Guest Professor) 15-22 October 1999. University of Science and Technology of China, Hefei, Anhui, P.R. China, 21 October 1999. J.N. Zhou was selected as one of the top people of the National Key Project for Basic Research in China. The function of brain and brain diseases (project # G1999054007). 2001 Beijing Institute for Neuroscience, Capital University of Medical Sciences, P.R. China, 22/23 October 2001 Anhui Medical University, Dept. of Neurobiology and the Dept. of Gerontology, Hefei, P.R. China, 25/26 October 2001 Dept. of Physiology, The First Military University, Guangzhou, P.R. China, 1 November 2001 Depts. of Neurology and Obstetrics/Gynaecology, University of Jakarta, Jakarta, Indonesia. 2002 Neuroscience Division of Yerkes Primate Research Center & Center for Neurodegenerative Disease, Emory University, Atlanta, GA, USA, 10-11 June 2002 2008 Hefei, University of Science and Technology of China, Lab of Prof. Jiang-Ning Zhou 16 October 2008: Lab talk on Human brain dissection demonstration; Master class; Lecture Stress system in human brain in depression and Alzheimer Zhejiang University, Hangzhou, Lab of Prof. Ai-Min Bao and Prof. Luo 20 October 2008: Proposals for a Brain Bank,Master Class, 21 October 2008: 3 Medical Psychology Lectures 23 October 2008: 4 Medical Psychology Lectures Institute of Neuroscience, Chinese Academy of Scienc, Shanghai, China 26 October 2008: Seminar: Lecture: Similarities and differences in the neurobiology of major depression and depression in Alzheimer's disease. Guest collaborators (and financial support) (for full list see Progress Reports) 23

1973/74 Dr. D.W. Lincoln (Bristol, UK). 1974 Dr. D.F. Salaman (Bristol, UK). 1975 Prof. J.v. Milligan (Canada). P. Liebrechts, A. Bernards (Plant physiology, UvA 1976 A. Dutton (Brabaham, UK). Dr. A.J. Thody (Newcastle, UK). Dr. M. Bevers (Veterinary Obst., Univ. Utrecht). M.M. Shehata (Cairo, Egypt). 1977 M. Visser (Gynaecologist, Amsterdam) (Foundation "De Drie Lichten"). 1978 Dr. J.T. Martin (Pomona, USA). Dr. M.M. Mitchell (Oxford, UK). Dr. E. Tribollet (Geneva, Switzerland). 1983 Dr. Ph. Valet (Geneva, Switzerland); (Swiss Med. Research Foundation). Dr. A. Crine (Liege, Belgium); (ETP-BBR long-term fellowship). 1983/88 Dr. R. Ravid (Jerusalem, Israel); (Foundation "Van den Houtenfund", The John Douglas French Foundation for Alzheimer disease, Los Angeles, USA). 1984 Dr. R. Lequin, A. Bogaart (Univ. Leiden). 1985 Dr. J. Figueroa (Ithaca, USA). 1987/94 Dr. R. Balàzs and N.J. Hack (London, UK). 1991/96 Dr. M. Panayotacopoulou (yearly work visits; postdoc, Athens, Greece) 1994 H. Timmers (Neurology, Univ. Nijmegen) Somatostatin in the nucleus tuberalis lateralis of Huntington patients. S. Heyn (USA) 1995/97 Z. Erkut (Turkey; Ph.D., fellowship from the MS Society) 1993/94 J.S. Purba (Indonesia, Deventer-Maas Stichting) 1992/96 J.N. Zhou (P.R. China; Ph.D., Nuffic fellowship) 1992/96 A. Salehi ((Iran; Ph.D., fellowship from the Shahid Behesti Univ. Tehran) 1997 M. Müller (Max-Planck Institut für Psychiatrie, Munich, Germany) 1997 S. Trottier (Lab. de Physiologie, Paris, France). 1997 K. Bergholm (Lab. for Pregnancy and Newborn Research, Cornell University, Ithaca, USA) 1997/98 A. Fernandez-Guasti (Dept. Pharmacol. Toxicol., Section of Experimental Therapeutics. Mexico City, Mexico) 1997/99 T. Ishunina (Dept. Histology and Embryology, Kursk State Medical University, Kursk, Russia) 1998/99 M. Alonso. Med. student University of Santiago de Compostela (Spain) 1998/99 J.N. Zhou and R. Liu, First Affiliated Hospital of Anhui Medical University, Hefei, (PR China) 1998/99 R.F. Liao (Ophthalmologist) Storage of corneas for transplantation, together with the Netherlands Ophthalmic Institute/ Cornea Bank. 1998 M. Panayotacopoulou (yearly work visits; postdoc, Athens, Greece) 1998 Y. Malidelis (National and Kapodistrian University of Athens, Dept. of Psychiatry): training period at the NIBR. 1998/99 A.P. Goldstone' (ICSM Endocrine Unit, Hammersmith Hospital, London, UK). 1999 D. Sunter (Imperial College School of Medicine, London, UK): quantification. A. Fernandez-Guasti (University Mexico): Sex hormone receptors in the human brain. V. Goncharuk (Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. T. Ishunina (Dept. Histology and Embryology, Kursk State Medical University, Kursk, Russia): Sex differences in the human hypothalamus. S. Kaiser (University of Münster, Germany): Instability of the social environment during pregnancy: effects on offsprings' brain development and behavior in guinea pigs. R-Y. Liu (Anhui Medical School, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer's disease. Y. Malidelis (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. M. Panayotacopoulou (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. H. Zang (Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer's disease. J.-N. Zhou (Anhui Medical School, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer's disease. 24

2000 A. Fernandez-Guasti (University Mexico): Sex hormone receptors in the human brain. A.P. Goldstone (Hammersmith Hospital, London, UK): Prader-Willi syndrome and obesitas. V. Goncharuk (Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. T. Ishunina (Dept. Histology and Embryology, Kursk State Medical University, Kursk, Russia): Sex differences in the human hypothalamus. S. Kaiser (University of Münster, Germany): Instability of the social environment during pregnancy: effects on offsprings' brain development and behavior in guinea pigs. R-Y. Liu (Anhui Medical School, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer's disease. Y. Malidelis (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. M. Panayotacopoulou (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. H. Zang (Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer's disease. J.-N. Zhou (Anhui Medical School, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer's disease. 2001 T. Ishunina (physician, University of Kursk, Russia): Sex differences in the human hypothalamus. R.Y. Liu (internist, First Affiliated Hospital of Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. V. Goncharuk (neurobiologist, Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. A.P. Goldstone (Hammersmith Hospital, London, UK): Prader-Willi syndrome and obesitas. S. Kaiser (University of Munster, Germany): Instability of the social environment during pregnancy: effects on offsprings brain development and behavior in guinea pigs. Y. Malidelis (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. Panayotacopoulou, M. (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. Y. Wu (Anhui Medical Universityy, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. J.N. Zhou (Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. 2002 A.M. Bao (Anhui Medical University, Hefei, P.R. China): The role of oestrogen receptors in depression. A. Hestiantoro (Jakarta, Indonesia): The correlation between estrogen receptor (ER) / changing and Alzheimer s disease neuropathology formation in the infundibular nucleus of the human hypothalamus. T. Ishunina (physician, University of Kursk, Russia): Sex differences in the human hypothalamus. R.Y. Liu (internist, First Affiliated Hospital of Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. V. Goncharuk (neurobiologist, Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. A.P. Goldstone (Hammersmith Hospital, London, UK): Prader-Willi syndrome and obesitas. D. Kontostavlaki (University of Athens, Greece): Expression of catecholamine-synthesizing enzymes in the human paraventricular and supraoptic nucleus: detection at the single cell level. Y. Malidelis (University of Athens, Greece): The supraoptic nucleus in schizophrenia. M. Panayotacopoulou (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. M. Panayotacopoulou (University of Athens, Greece): The supraoptic nucleus in schizophrenia. Y. Wu (Anhui Medical Universityy, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. J.N. Zhou (Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. 2003 A.M. Bao (Anhui Medical University, Hefei, P.R. China): The role of oestrogen receptors in depression. A.. Hestiantoro (Jakarta, Indonesia): The correlation between estrogen receptor (ER) / changing and Alzheimer s disease neuropathology formation in the infundibular nucleus of the human hypothalamus. H. Wiryawan (Jakarta, Indonesia): The correlation between estrogen receptor (ER) / changing and Alzheimer s disease neuropathology formation in the infundibular nucleus of the human hypothalamus. T. Ishunina (physician, University of Kursk, Russia): Sex differences in the human hypothalamus. 25

R.Y. Liu (internist, First Affiliated Hospital of Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. V. Goncharuk (neurobiologist, Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. D. Kontostavlaki (University of Athens, Greece): Expression of catecholamine-synthesizing enzymes in the human paraventricular and supraoptic nucleus: detection at the single cell level. Y. Malidelis (University of Athens, Greece): The supraoptic nucleus in schizophrenia. M. Panayotacopoulou (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. Y. Wu (Anhui Medical Universityy, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. L. Wu (University for Science and Technology of China, Hefei, Anhui, China): Isolation of rat and human neural precursor cells and co-culture with human postmortem brain tissue slices. J.N. Zhou (Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. 2004 A.M. Bao (Anhui Medical University, Hefei, P.R. China): The role of oestrogen receptors in depression. A. Hestiantoro (Jakarta, Indonesia): The correlation between estrogen receptor (ER) / changing and Alzheimer s disease neuropathology formation in the infundibular nucleus of the human hypothalamus. H. Wiryawan (Jakarta, Indonesia): The correlation between estrogen receptor (ER) / changing and Alzheimer s disease neuropathology formation in the infundibular nucleus of the human hypothalamus. T. Ishunina (physician, University of Kursk, Russia): Sex differences in the human hypothalamus. R.Y. Liu (internist, First Affiliated Hospital of Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. V. Goncharuk (neurobiologist, Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. D. Kontostavlaki (University of Athens, Greece): Expression of catecholamine-synthesizing enzymes in the human paraventricular and supraoptic nucleus: detection at the single cell level. Y. Malidelis (University of Athens, Greece): The supraoptic nucleus in schizophrenia. M. Panayotacopoulou (University of Athens, Greece): Colocalization of tyrosine hydroxylase with vasopressin and oxytocin during activation. Y. Wu (Anhui Medical Universityy, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. L. Wu (University for Science and Technology of China, Hefei, Anhui, China): Isolation of rat and human neural precursor cells and co-culture with human postmortem brain tissue slices. J.N. Zhou (Anhui Medical University, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. 2005 A.M. Bao (Anhui Medical University, Hefei, P.R. China): The role of oestrogen receptors in depression. A. Hestiantoro (Jakarta, Indonesia): The correlation between estrogen receptor (ER) / changing and Alzheimer s disease neuropathology formation in the infundibular nucleus of the human hypothalamus.t. Ishunina (physician, University of Kursk, Russia): Sex differences in the human hypothalamus. V. Goncharuk (neurobiologist, Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. Y. Wu (Anhui Medical Universityy, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. L. Wu (University for Science and Technology of China, Hefei, Anhui, China): Isolation of rat and human neural precursor cells and co-culture with human postmortem brain tissue slices. 2006 A.M. Bao (Anhui Medical University, Hefei, P.R. China): The role of oestrogen receptors in depression. A. Hestiantoro (Jakarta, Indonesia): The correlation between estrogen receptor (ER) / changing and Alzheimer s disease neuropathology formation in the infundibular nucleus of the human hypothalamus. T. Ishunina (physician, University of Kursk, Russia): Sex differences in the human hypothalamus. V. Goncharuk (neurobiologist, Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. Y. Wu (Anhui Medical Universityy, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. L. Wu (University for Science and Technology of China, Hefei, Anhui, China): Isolation of rat and human neural precursor cells and co-culture with human postmortem brain tissue slices. 2007 A. Garcia-Falgueras (Postdoctoral fellowship from the Ministry of Education and Science, Spain). Sexual differentiation of the human hypothalamus. 26

A.M. Bao (Anhui Medical University, Hefei, P.R. China): The role of oestrogen receptors in depression. A. Hestiantoro (Jakarta, Indonesia): The correlation between estrogen receptor (ER) / changing and Alzheimer s disease neuropathology formation in the infundibular nucleus of the human hypothalamus. T. Ishunina (physician, University of Kursk, Russia): Sex differences in the human hypothalamus. V. Goncharuk (neurobiologist, Cardiovascular Research Center, Moscow, Russia): Anatomical analysis of the hypertensive hypothalamus. Y. Wu (Anhui Medical Universityy, Hefei, P.R. China): Clinical and neuropathological comparison of vascular dementia and Alzheimer s disease. L. Wu (University for Science and Technology of China, Hefei, Anhui, China): Isolation of rat and human neural precursor cells and co-culture with human postmortem brain tissue slices. S.-S. Wang (Hefei National Laboratory for Physical Sciences at Microscale and Department of Neurobiology and Biophysics, Life Science School, University of Science and Technology of China, Hefei, Anhui, P.R. China): Gene expression analysis in the human hypothalamus in depression by laser micro-dissection and real time PCR: the presence of multiple receptor imbalances. L. Shan (Chinese Government and Zhejiang University, Zhejiang, P.R. China): The histaminergic system in the human hypothalamus in health and disease. Some external funds 1976/79 FUNGO-project no. 35-07 'Physiology and pathology of hypothalamopituitary systems'. 2 technician positions for 3.5 years and 1 technician position for 6 months. 1980/84 ZWO-project Geriatrics 'The vasopressin and oxytocin innervation of the limbic system in the rat and in human during aging' (1 year ZWO, 3 years FUNGO; E. Fliers). Foundation 'Van den Houtenfonds', Commissie Diergeneeskundige Vereniging, Utrecht, Netherlands - project H.P. Oosterbaan (3 months) 1983/84 SOOM-project nr. 830804 'Influence of environmental factors on the sleep pattern and activity of oxytocin and vasopressin producing neurons during aging in the rat' (2-year position P. van Gool). 1983/85 "Van den Houtenfonds", 2-year postdoc fellowship R. Ravid. 1986/89 ZWO-project (3-year thesis position E. Goudsmit). 1985/88 3-Year fellowship R. Ravid from The John Douglas French Foundation (Los Angeles, USA). 1986/87 SOOM-project Brainbank (2 years, 1 part-time position, M. Hofman). 1986/90 Wetenschapsbeleid - Brainbank (4 years, 2 part-time positions: E. Fliers, R. Ravid, T. Wesseling). 1987/88 ZWO-fellowship for Dr. R. Balàzs (UK) 1988/89 Fellowship M.B.O.M. Honnebier for collaborative project with Prof. P.W. Nathanielsz, Cornell, Ithaca, USA. 1988/92 MEDIGON-oio-project for E.J. van Zwieten 1988/ Funding for Brain Bank Foundation 1988 2-year thesis position W. Witting (Alzheimer Conference, Amsterdam) 1989/93 4-year thesis position "Stichting Gezondheidsonderzoek" for J. van de Nes, with Dr. P. Eikelenboom (Valerius Clinic, Free University, Amsterdam) 1989/93 half-time technician "Stichting Gezondheidsonderzoek" for 4 years (J.P.H.M. Ploegmakers). 1990/94 F.C. Raadsheer, 'AIO', Neurowetenschappen Amsterdam, 4 years, with Prof.dr. F.J.H. Tilders. 1990 D.F. Swaab was a recipient of a Senior Travel Fellowship of the Alzheimer Society of Canada. 1990/92 Praeventiefonds #28-1921. De invloed van het zoutbeperkte dieet op vasopressine en oxytocine gedurende de zwangerschap en het puerperium (C.E.A. van Boxtel) 1990/95 MS Brain Bank #89-45ms (6 years) (J.P.H.M. Ploegmakers, G. Beek) 1990/91 Vitatron-Stimulus project, together with M. Mirmiran, 2 'AIO's' (E. van Someren and W. Witting) and a postdoc (W.A. Van Gool) 1990/ Structural annual support of ƒ80,000.- from KNAW for the Netherlands Brain Bank. Additional funds from the Ministry of Education and Science 1990 Grant from the Sandoz Foundation for 3 months of Gerontological Research in Basel (E. Goudsmit) 1990/94 4-year thesis position MEDIGON (P.J. Lucassen) 1990 3-month grant for A.M. Neymeyer-Leloux (Obstetrics, Nijmegen) 1991 2-year postdoc grant from KNAW (E. Goudsmit) Circadian rhythms in MS (E. van Someren, MS Foundation) 1992 3-year thesis project J. Purba (Deventer-Maas Stichting) 27

4-year thesis position Ahmad Salehi (Ministry of Health and Education of the Islamic Republic of Iran) 1991/96 W.J.G. Hoogendijk, AGIKO, NWO-MW # 900-716-019 & # 900-557-007. 1992/93 12-month thesis project Jiangning Zhou (Nuffic) 1993 1-year postdoc E. Goudsmit (Hersenstichting Nederland) 1993/95 MS-foundation positions (2 thesis positions and 1 post-doc position # MS92-111). 1993 Biomed I Project NO PL 931359: European Brain Bank Network for Neurobiological Studies in Neurological and Psychiatric Disorders (E.B.B.N.). Biomed I Project NO PL 931536: Hormonal and genetic disorders in gender-specific brain differentiation. NWO: 3-year post-doc position: sexual differentiation of the human brain (M. Fodor, #900-552- 134). 1993/95 Stipt project, prolonged by Senter (DFL. 884.700). 1995/97 MS-foundation 2-year fellowship for PhD student (Z. Erkut) # 94-188 1995 International Alzheimer Foundation (a total amount of DFL. 400.000,= for 4 years for the Netherlands Brain Bank). 1996 4-year subsidy of DFL. 142.745/year (total amount DFL. 713.725) from the Friends of MS Research Foundation for "Applications of the Netherlands Brain Bank for Multiple Sclerosis" (95-243 MS). 6 months post-doc fellowship for A. Meyer (Ulm) en SRY-expression in human hypothalamus (KNAW). Structural support for the Netherlands Brain Bank from the Royal Netherlands Academy of Sciences of DFL. 150.000,=/year. 3 years postdoc (Inge Huitinga) and technician (Maarten van der Camme) from the Netherlands MS foundation, together with Prof. Dr. F.J.H. Tilders (Free University, Amsterdam). 1 technician for the Netherlands Brain Bank (Pharmagene, UK), with Dr. R. Ravid. 1997/98 1 fellowship Ter Meulen Fund (W.C.J. Chung), together with Prof. G.J. de Vries (Dept. Psychol. Univ. Massachusetts, Amherst, USA). D.F. Swaab is mentor of the project. 1997 Netherlands Brain Bank. Structural support from KNAW, DFL. 425.000 per year. Platform Alternatives for Animal Experiments (PAD 96-07). 0.5 postdoc for the Netherlands Brain Bank for 3 years. For M. Fodor (postdoc) Dfl. 50.000 from Netherlands Brain Foundation for sex hormone receptors Alzheimer s disease. Bedrijfsvereniging Horeca Dfl. 69.584,= for E.Scherder and E.J.W. van Someren. Pharmacia & Upjohn (Sweden) SEK 200.000, research fellow Prader-Willi syndrome. ISAO, Dfl. 150.000 (4-year fellowship A. Salehi). Pharmagene Dfl. 50.000 (NBB technician in 1998) Collaboration with First Affiliated Hospital of Anhui Medical University, P.R. China (financed by KNAW with Dfl. 62.500). Solvay-Duphar, Dfl. 50.000 for the Netherlands Brain Bank 1998 Merck Research Laboratories $ 25.000 for collaboration in the field of obesitas. Praeventiefonds (2830030) Dfl. 943.000 (Prevention of nightly restlessness and depression in elderly in an early stage of dementia). For a postdoc, Ph.D. student and other costs. Fliers, Wiersinga, Swaab. Hypothalamic modulation of non-thyroidal illness. 1 PhD student (NWO) European Charcot Foundation, Dfl. 241.000,= (1 year fellowship for Z. Erkut) Dfl. 100.000,=/year for two years for a study on eating disorders (Merck & Co. Inc. USA). Collaboration with First Affiliated Hospital of Anhui Medical University, P.R. China (financed by KNAW (CCWOCC 99 CD PO18) with Dfl. 75.000). 1999 Collaboration with First Affiliated Hospital of Anhui Medical University, P.R. China (financed by KNAW (CCWOCC 99CDPO18) with Dfl. 80.000). Merck Research Laboratories $ 25.000 for collaboration in the field of obesitas. '99/2000 Dfl. 10.000/year from the Netherlands Brain Foundation for the Netherlands Brain Bank. '99/2004 MS Fellowship awarded to Inge Huitinga from the Stichting Vrienden MS Research 1999 Dfl. 50.000 from the International Foundation Alzheimer Research for the NBB 2000 Dfl. 50.000 from Solvay Duphar for the Netherlands Brain Bank 2000/02 Dfl. 190.000 from NWO for scientific collaboration between the Netherlands and the Russian Federation on Structural and Functional Analysis of the Human Hypothalamux: focus on hypertension and sex differences (together with Prof. R.M. Buijs, # 047-008-002) 28

2000/04 Dfl. 333.333 from NWO for one Ph.D., materials and technical help for the Virtual Research Institute Disease of the Elderly. 2000 Dutch Alzheimer Foundation Dfl. 25.000 (Brain Bank project Dubelaar). $25.000 from Merck for one postdoc and one technician For MS branch of the Netherlands Brain Bank Dfl. 1,230,000 (2001-2006) Project #00-406 from the Foundation Friends of MS Research (Swaab & Ravid). For the Netherlands Brain Bank, Dfl. 50,000 from the Internationale Stichting Alzheimer Onderzoek. Federa Prize, Dfl. 5000. Dfl. 50.000 from Solvay Pharmaceuticals for the Netherlands Brain Bank Dfl. 130.000 for Agiko project from NWO (G. Meynen) with W.J.G. Hoogendijk. 2001 US$ 50,000 for NIBR from Merck & Co. Inc. Distribution of melanin concentrating hormone and its receptors in the human brain and its role in human obesity. 5,000,000 Jp Yen (approx. Dfl. 100.000). Japan Foundation for Aging and Health for the project on Light and Melatonin in Alzheimer patients (E.J.W. van Someren/D.F. Swaab). Dfl. 67,000 from the Royal Netherlands Academy of Arts and Sciences for continuation of the China project with Anhui Medical University in Hefei, P.R. China. Dfl. 47,025 additional support for the foundation of an MS-CSF bank (project 97-310 ms). Dfl. 12,000 ZON-MW for the Netherlands Brain Bank. Dfl. 100,000 (bequest Mrs. C.C. Smit). 2002 Dfl. 340.000 (2 years postdoc H. Lacerda, 0.5 technician and materials from KNAW). Together with J. Verhaagen. 37.040,60 (bequest for NBB). 43.343,00 from KNAW for collaboration with Anhui Medical University, P.R. China Nuffic fellowships voor D. Kontostavlaki (10 months) 415,000 (Solvay) together with J. Verhaagen for molecular biology 68,000 from ISAO (#02505) with Dr. R. Verwer, for postmortem human slice culture 22,690 from ISAO with Dr. R. Ravid for the Netherlands Brain Bank. 22.689 from Hersenstichting Nederland (10F02.12) for project Activation of neurons in the infundibular nucleus in menopause prevents the occurrence of Alzheimer changes (A. Hestiantoro). 2002/03 50,000/year from Merck. 2003 25,000 for PhD Y. Wu, Hersenstichting Nederland (11F03.07) Project: early changes in pineal melatonin synthesis and noradrenergic regulation in the course of Alzheimer s disease. 41,313 from KNAW for collaboration with Anhui Medical University, P.R. China (03CDP001) 25.000 from Merck. 23.800 from ISAO (#03508) for project Relation between sex hormone receptors and Alzheimer changes planned for period of 1 November 2003 to 1 November 2005 for A. Hestiantoro. 25.000 from Hersenstichting Nederland for project Reactivation of cholinergic neurons in post-mortem cultured slices of Alzheimer patients (project # 11F03(2).13 for PhD (L. Dubelaar). 25.000 from Merck (USA) 2004 25.000 from Merck (USA) $ 8.000 from Merck (USA) for Alzheimer advice 14.000 from Organon (Netherlands) 1000 from HCN (Elsevier) 2005 $ 50.000/year for project on regulation of eating and metabolism from Merck (USA) 14.000 for pilot study extension (Organon) 30.000 for MS research Inge Huitinga from Stichting MS Research 29.000 Talent Stipendium from NWO for Anneke Alkemade (Neurogenesis in mice with a mutant thyroid hormone receptor alpha1 gene). 23.044 in royalties from Elsevier ISAO (#05501) for Ronald Verwer 2005/08 126,977, PWS - EU 2006 3437 in royalties from Elsevier 127.000 from PWS - EU 18.170 in royalties from Elsevier 300.000 TIPharma for a technician 2007 38.000 The Chinese Government. China Scholarship Council, 4 year Ph.D for Shan Ling. 29

2008 25.000 from the Hersenstichting Nederland (project: Change in the ratio of ERα wild type and splice variants in aging and Alzheimer's disease (with T. Ishunina). 21.714,12 Royalties from Elsevier 1.000,71 Royalties boek Geurts (Scriptum Psychologie) 11.990,06 Columns NRC Handelsblad etc. 204.826,00 CHDI Foundation A-2376 "The Hypothalamus in Patients with Huntington's Disease". 2009 34.000,00 KNAW China Project 2009L 09CDP011. $ 59.346,00 CHDI Management Inc. For research project The Hypothalamus in Patients with Huntington's Disease. $ 265,125.00 (together with Harvard University, USA, Nikos Markis and Jill Goldstein. Joint project Identification and Validation of Human Hypothalamic Nuclei in-vivo and ex-vivo). 24.757,95 Royalties from Elsevier 2300 Fee for columns in NRC Handelsblad. 2010 12.000 Fee for editorial work for Elsevier 2011 100,50 (royalties Scriptum) 275,92 (royalties Elsevier) 8060,85 (royalties Elsevier) 1000 (royalties Elsevier) 800 (De Booij Party & Congres) 2000 (De Booij Party & Congres) 3000 (Graham Publishing) 3200 (Graham Publishing) 15.894,93 (Royalties Elsevier) 150.000 (for 2 years for project with Sabina Luchetti) (Stichting Internationaal Parkinson Fonds) Teaching (for lectures see list) Students 1972 H. Veerkamp (biochemistry). 1973 F.W. van Leeuwen (biology). 1974/75 Chr.W. Pool (biology). 1974 Y. Koenders (biology). 1974/75 F. Nijveldt (pharmacy). 1975/77 M. Visser (gynecologist in training). 1975 T. Stelling (medicine). 1976 R.M. Buijs (biology). K. Hiemstra (biology. 1977 M. de Boer (biochemistry) (April 25, preliminary examination). M. Evers (biology). P. Jansen (biology). 1978 P.R. Oosting (medicine). 1979 E.L. Baruch-Virransalo (biochemistry). J.P. ter Borg (biology). G.J. de Vries (biology). L.P.C. Schot (biology). D.N. Velis (medicine). 1980 E. Fliers (medicine). 1981 S.E.F. Guldenaar (biology). T. Partiman (medicine). 1982 M. Fiolet (linguistics). 1983 P. van de Hooff (biology) (March 20, 1984 prelim. examination) W. Duetz (chemistry) (March 23, 1984 preliminary examination). 1984 J.E. Hoogendijk (M.D., UvA). (thesis: Rhythmical changes in biohysical parameters in relation to fetal well-being; a literature survey). S. Mosselman (biology) (June 22, 1984 preliminary examination). C.P.E. Rodenburg and P.M. Engelfriet (obstetrics) (Master's thesis). Th. Lammertse (biology, UvA) (October 19, 1984; preliminary examination: "From Neuron to Brain"). 1985 J.H.Th.M. Koelmans (M.D., physician, Univ. Leiden). 30

E. Goudsmit (M.D., Univ. Amsterdam). P. v.d. Hooff (biology, Univ. Amsterdam) (May 22, chairman degree examination board). D.A. van Waardenburg (medicine, UvA). E.C. Jongejan (medicine, UvA). H.V. Willemswaard (psychology, Univ. Amsterdam). F. Zantvoord (psychology, UvA). 1986 B. Roozendaal (medical biology, UvA) (February 13, 1986: preliminary examination). G. Borst (medicine, UvA, with Dr. S. Leung, Canada). E. Schulz-van Dongen (psychology, Univ. Utrecht). C.A. Chee (pharmacy, UvA). E. van Leengoed (biology, UvA), (prelimary examination 28-10-86; thesis on `Perinatal stress') W. Hoogendijk (medicine, UvA) (with D. Troost, AMC) E. van Zwieten (biology, Free Univ., Amsterdam) W. van der Berg (psychology, UvA) 1987 W. Kos (chemistry, UvA) B. Roozendaal (medical biology, UvA) W. Witting (medicine, UvA) (with M. Mirmiran) C.J.J. Bogte (physician, UvA) (with E. Goudsmit) M.B.O.M. Honnebier (medicine, UvA) 1988 V. Lamme (medicine, free subject, cum laude examination 31 August 1988) 1988/89 R. Korthals Altes (medicine, UvA) J. Parlevliet (medicine, UvA, exchange visit to Prof. J. Hardy in Montreal, Canada) 1990 T.H. Lange (medicine, exchange visit to Beth Wolfson hospital, Holon, Israel) 1991 L. Beerepoot (medicine, UvA) R.M. Hoek (biology, Free University, Amsterdam) De wetenschap en de samenleving: een gespannen relatie. T. Ehlhart (biology, State University Utrecht) Development of vasoactive intestinal polypeptide neurons in the human suprachiasmatic nucleus. J. Mijnster (medical biology, Leiden) tentamen immunocytochemische methoden. 1991/92 M. Boon (medicine, Leiden) Alz-50 staining in the hypothalamus of Down syndrome patients. 1992 J.N. Zhou (medicine, People's Republic of China) Vasoactive intestinal polypeptide (VIP) neurons in the human suprachiasmatic nucleus (SCN) in relation to Alzheimer's disease, age and sex. 1992 A. Salehi (medicine, university of Tehran, Iran) Development of a double staining protocol for the Golgi apparatus and vasopressin in neurons of the paraventricular and suprachiasmatic nuclei of the human hypothalamus. 1993 N.L. van Woerden (medicine, UvA) training period with Prof. F.H. Gage, San Diego, USA) Ultrastructural characterization of 19 month old genetically engineered fibroblast grafts in the rat striatum. 1993 T. Ehlhart (biology, State University of Utrecht). Supervision of graduation thesis entitled "Laughter". 1993/94 N. Noppen (medical biology, UvA). Localization of TRH in the human hypothalamus & neurobiology of schizophrenia. 1994 J. Gopie (Medicine, Free University, Amsterdam). Immunocytochemische detectie van DNA-schade in hersencoupes van de rat; een parametrische studie (with P.J. Lucassen). 1994 W.G.J. Chung (medical biology, Free Univ., Amsterdam). Parametric studies of DNA damage detection and its distribution in human and rat brain by means of in situ end labeling and DNA gel electrophoresis (with P.J. Lucassen). W.K.H. Man A Hing (medical biology, Free University, Amsterdam). Apolipoprotein A4: A newly found risk factor for Alzheimer's disease (with A. Salehi). 1994/95 J.M. Bakker (medicine, UvA). Neuronal density around senile plaques is lower than that of control points (with A. Salehi). 1995 A. de Vries (medicine, UvA). Regulation of the metabotropic glutamate receptors in astrocyte cultures. With R. Balázs in Irvine, California, USA. 1995 F.P.M. Kruijver (medicine, UvA). Sexuele oriëntatie, vasopressine en oxytocine. 1995 Winston K.H. Man A Hing (Free Univ. Amsterdam). Fetal cardiovascular and endocrine responses to partial occlusion of the umbilical cord in fetal sleep. At Cornell, Ithaca, USA, with Prof. P.W. Nathanielsz. 1995/96 L.T.G. te Bulte (biology, UvA) The suprachiasmatic nucleus in depression (with J.N. Zhou). 1996 V.M.C.W. Spaander (medicine, Univ. Amsterdam) /A4 and Tau in parahippocampal gyris and cingu - late cortex. (Dr. L.M. Gonzalo, University of Navarra, Dept. Anatomy, Pamplona, Spain). 1996 L.C.G. Hahn (medicine, AMC, keuzeonderwijs) Critical illness neuropathy. Rudolf-Virchow ziekenhuis, 31

Berlin, Germany. 1996 W.C.J. Chung (biology, Free University, Amsterdam) long training period and supervision of end paper "The involvement of cell death in the development of sex differences in the vertebrate central nervous system". Supervision was done in collaboration with Prof. G.J. De Vries, Univ. Massachusetts, USA. 1996 C.G.C. van der Wees (medical biology, Free University, Amsterdam) supervision of end paper on Anorexia and bulimia nervosa. 1997 E.W. Daalman (biology, UvA) Sexuele differentiatie. 1996-97 E.J.G. Dubelaar (biology, UvA) APOE subtype amd metabolic activity in the nucleus basalis of Meynert of Alzheimer patients (with A. Salehi). 1997 P.M.A.F. van Gils (biology, Univ. Utrecht) Sex differences of galanin and cholecystokinin (CCK)-expressing neurons in the human sexually dimorphic nucleus (SDN) (with J.N. Zhou) 1997/98 E.W. Daalman (medical biology, UvA) Human hypothalamus: sexual dimorphism, gender and sexual orientation. (graduation thesis) 1997 B. Noort (University of Pamplona, Spain) Medial temporal lobe neurofibrillary tangle densities in Alzheimer s disease (with R.I. Insausti). 1997 S. Matthijs (Free University, Amsterdam) Melatonin and the mammalian pineal gland. 1997 R. Riemersma (medicine, UvA) AVP-mRNA expression in the suprachiasmatic nucleus in depression. 1997-98 R. Riemersma (medicine, Univ. Amsterdam and Dept. Psychiatry, Max-Planck Institute) Munich, Germany 1997 V. Oleana (Faculty of Medicine, AMC, Amsterdam): Apoptosis in Alzheimer s disease. 1998 L. Ligtenberg (Biology, Univ. Utrecht): Sex differences of galanin and CCK expressing neurons in the human SDN-POA. 1998 V. Gonzalez-Martinez (Medicine, Spain): Apoe type and sex differences in the NBM of Alzheimer patients. 1998 D. Gans (Medicine, AMC, Amsterdam): training period in Israel. B. Noort (Medicine, AMC, Amsterdam): training period in Spain (Pamplona); paper Medial temporal lobe neurofibrillary tangle densities in Alzheimer s disease. 1998 F. Stam (Biomedical Sciences, University of Leiden): training period in the LACDR, Leiden; report: The glucocorticoid receptor in the human brain. 1998 M. Engelen (Medicine, AMC, Amsterdam): training period in the USA (Lab. for Pregnancy and Newborn Research, with Prof. P. Nathanielsz). 1998 G.B. ten Wolde (Psychology, UvA): The pathology of the hypothalamus in Multiple Sclerosis. 1998 N. D. Kruyt (Medicine, UvA): 10-month training period at thedept. of Psychobiologia Universidad Nacional de Education a Distancia, Madrid. Supervision in Madrid by Dr. C. Sandi, supervision in Amsterdam by Dr. J. de Bruin and Prof. dr. D.F. Swaab (NIBR). 1998 T. Roelofs ( UvA): Visualization of estrogen receptor-containing neurons in the human hypothalamus by using the antibody ER (C-314). Supervision F. Kruijver and D.F. Swaab 1998 E.T. te Beek (Medicine, UvA): An inquiry on apoptosis in the central nervous system 1998 J. Drenth (UvA): Galanin-immunoreactive cells in the human sexually dimorphic nucleus of the preoptic area (SDN-POA). Supervision by J.N. Zhou. 1999 M. Engelen (Medicine, UvA): Wetenschappelijke stage bij Prof. Dr. P.W. Nathanielsz, Cornell University, Ithaca, NY. Project: The effect of dexamethasone on the functional response of arterial resistance vessels in the ovine fetus. 1999 R. van Houdt (UvA): Interleukin-1 mrna in neurons of the human hypothalamus. 1999 M. van de Wetering (UvA): Axonal damage in the hypothalamus of Multiple Sclerosis patients. 1999 E.M. Kraan (UvA): Androgen-receptor immunoreactivity in the hypothalamus of transsexuals, aged castrated and non-castrated males. 1999 S. Markx (UvA): Ziels en zenuwziekten: reïnterpretatie. Een analyse van de geestelijke gezondheidszorg met psychiatrie als focus. 1999 E. Lyklema (UvA): ApoE genotyping on paraffin-embedded formalin-fixed human brain tissue. 2000 S. Markx (Mount Sinai Hospital, NY, USA) Phenomenological, neuroimaging, genetic and pharmacological studies of patients with schizophrenia. Superviser in USA: Dr. Joseph Friedman, Mount Sinai, NY. T. Klooker (Medicine, UvA): Morphine has no effect on the cerebrospinal fluid cortisol levels of Alzheimer patients and controls: a post-mortem study. E.M.R. Cohen (Karolinska Institute, Stockholm, Sweden): A computerized monkey brain atlas for anatomical and functional mapping (Balasz Gulyas, Karolinska Inst. Stockholm, Sweden). P.M.A.F. van Gils (Biology, Univ. Utrecht): Gender-specificity in the etiology of human homosexuality. R. Willemse (Biology, UvA): Localization of interleukin (IL)-I type I and type II receptor in the human 32

hypothalamus by use of immunocytochemistry, in situ hybridization and (single cell) PCR techniques. R.A. Balesar (Medical Biology, Free University, Amsterdam): Localization of estrogen receptors alpha and beta in the human hypothalamus and its adjacent areas, and Why is remyelination limited in multiple scleroris? S. Bijl (Medicine, UvA): Vasodilatory effect of isosorbid dinitrate (ISDN) applied to the extremities. S. Collins (Medical Biology, University of Utrecht): Sleep and thermoregulation. A. Espila (Medicine, University of Malage, Spain): Estrogen receptor expression in the human hypothalamus. M. Gholami (Medicine, UvA): Estrogen receptor expression in the human hypothalamus. A. Harwig (Medicine, UvA): Expression of glucocorticoid receptor mrna in human hypothalamus. N. Hoekstra (Medicine, UvA): Development of demasking procedures for the estimation of the endogenous circadian rhythms in core temperature. R.A. Hoekstra (Medical Biology, UvA): Prevention of nightly restlessness, depression and agitation in demented patients by stimulation of the circadian system with light and melatonin. A. Kalis (Neuropsychology, UvA): Prevention of nightly restlessness, depression and agitation in demented patients by stimulation of the circadian system with light and melatonin. E. Kraan (Medicine, UvA): Androgen-receptor immunoreactivity in the hypothalamus of transsexuals, aged castrated and non-castrated males. L. Ligtenberg (Biology, University Utrecht): Galanin expression in the human hypothalamic SDN-MPOA and its relation to age and sex. M. Pticek (Psychology, UvA): Development of long-term assessment methods for tremor and dyskinesias. C. Smeets (Biology, UvA): Prevention of nightly restlessness, depression and agitation in demented patients by stimulation of the circadian system with light and melatonin. P.M.A.F. van Gils (Biology, University Utrecht): Gender-specificity in the etiology of human homosexuality. C.J.M. van Ginkel (Laboratory School Nijmegen): Tracing of neural connections in post-mortem human brain slices during long-term culturing. R.S. van Hutten (Psychology, Free University, Amsterdam): The effect of long-term bright light and melatonin treatment on circadian rhythms, sleep, behavior, cognition and emotion in demented elderly. P. van Tijn (Biology, UvA): Frameshift mutations in the GFAP-mRNA in astrocytomas. Y. Yukahari (Medicine, University Kyoto, Japan): The expression of progestin receptors during the development of the human hypothalamus. S. Zijp (Biology, UvA): The effect of peripheral nerve stimulation on EEG in Alzheimer's disease. 2000/01 F. Goezinne (Medicine and Medical Biology, UvA): Effect of obesity and sex hormones on cocaine- and amphetamine-regulated transcript (CART) neurons in the infundibular nucleus of the human hypothalamus: a post-mortem study using immunocytochemistry and in situ hybridisation. M. Balfoort (Medical Biology, UvA): Distribution of estrogen receptor in the human hypothalamus during development. R.E.L. Hezemans (Biology, UvA): The influence of sex hormones on the development of transsexuality. 2001 M. Bolkenbaas (Biologie, UvA): Estrogen receptor expression in the hippocampus and temporal cortex of vascular dementia and Alzheimer disease. D.J.C. Komen (Medicine, University Leiden): The role of progesterone receptors during the sexual differentiation of the bed nucleus of the stria terminalis. D. Mobach (Medical Biology, Vrije Universiteit, Amsterdam) Distribution of androgen receptor in the bed nucleus of the stria terminalis in human brain development in relation to sexual differentiation. 2002/03 C. Holst (Psychology, UvA) Expression of interleukin-1 receptor antagonist in neurons in postmortem human brain tissue of multiple sclerosis and control cases. F. Lambers (Medicine, UvA) The effect of complex environment on the neuroanatomy of Fragile X knockout mice. (Beckman Inst., University of Illinois, Urbana-Champaign, USA) V. Oleana (Medicine, UvA) Apoptosis vs. necrosis. H. van Dijk (Medicine, UvA) Is the real-time quantitative polymerase chain reaction possible on cultured postmortem human brain tissue? B.O. Fabriek (Medical Biology, University of Utrecht) Distribution of Type II and III deiodinase (D2, D3) peptide and mrna expression in the human hypothalamus and anterior pituitary. F. de Vries (Medicine/Psychology, UvA) Synapse development in Fragile-X knockout mice (Beckman Inst., University of Illinois, Urbana-Champaign, USA). L. Ligtenberg (Biology/University of Utrecht) Galanin immunoreactivity in the human sexually dimorphic nucleus. 33

W. ter Meulen (Medicine, UvA) Metabolic alterations in NBM neurons in the elderly: activation in MCI, decompensation in AD. W. Spijkstra (Medical Biology, UvA) The role of melanin concentrating hormone receptor in the human hypothalamus in the control of feeding and metabolism. H. den Hertog (University of Leiden) The orexin system in human narcolepsy. 2004 D. Velseboer (UvA) Sexual differentiation of the Bed Nucleus of the Stria Terminaliin a patient with the complete androgen insensitivity syndrome. 2005 M. Diemel (UvA) begeleiding wetenschappelijke stage in Argentinië (Cordoba, Dr. Hugo Carrier). R. Fronczek (Faculty of Medicine, University of Leiden). Narcolepsy & the Hypocretin System. R.A. Peters (Faculty of Biology, Radboud University Nijmegen). Structural differences in the human hypothalamus in relation to gender and sexual orientation. M. de Leeuw (Faculty of Medicine, UvA). Are circulating sex hormone levels reflected in the expression of sex hormone receptors and aromatase in the medial mamillary body of the human hypothalamus? S. de Wit (Faculty of Medicine, UvA). Estrogen-receptor-alpha expression in paraventricular corticotropin-releasing hormone neurons in multiple sclerosis (MS). 2005/06 K.M. Wong (Faculty of Medicine, UvA). Orexine receptoren bij Prader-Willi. T. Bets (Faculty of Biology, UvA). Sexual differentiation of the brain: relation to sexual orientation and gender. G. Micolo (Faculty of Biology, UvA). Movie on Homosexuality. E.V.S. Hessel (Faculty of Biology, University of Utrecht) Expression of deiodinase type 3 (D3) in the paraventricular nucleus (PVN) of patients with non thyroidal illness. 2006 M. Louwet (Faculty of Medicine, UvA). The effects of orchidectomy and testosterone replacement in an animal model of obsessive compulsive disorder (at Centro de investigacion y de estudios avanzados del instituto politecnico nacional, guest supervisor: Prof. dr. Alonso Fernandez-Guasti). S.I. Lutgens (Faculty of Science, UvA). The inhibiting influence of oestrogen in the disease process of multiple sclerosis. J.J. Parga (Harvard, Massachusetts, USA). Sexual differentiation of the human brain. A. Oostra (Universidad Autonoma de Madrid). Cellular bases for hypocretin-mediatedmodulation of sleep-wake states within the pontine tegementum of the cat. M. Végh (Vrije Universiteit, Amsterdam). Sexual dimorphisms of the hypothalamo pituitary adrenal axis in schizophrenia; a pilot study. P.I. Koesoebjono (Universiteit van Amsterdam). Neurobiological factors in postpartum depression. E. Nelis (Universiteit van Amsterdam). Functional complexes of AChE and signalling elements in Alzheimer's disease. S. van Loon (Vrije Universiteit, Amsterdam). Sex differences in the SDN-POA of the human hypothalamus; a pilot study. 2007 A.M. Ragel Martínez-Villalba (Senior Medical Student, Faculty of Medicine, Universidad Autónoma de Bucaramanga, Colombia). J. Ribbens (Faculty of Medicine, UvA). The hypothalamo pituitary adrenal axis in schizophrenia. I. Bontebal (Faculty of Medicine, UvA). The influence of estrogen on the antidepressant effect of citalopram. Guest tutor: Dr. A. Fernandez-Guasti, Centro de Investigacion y de Estudios Avanzados del Instituto Politecnico Nacional. Departamento de Farmacobiologia, Mexico. M. Klouwens (Faculty of Biology, UvA). Transsexualism. The sexual brain paradigm. K. de Jong (Faculty of Medicine, UvA). The role of the medial prefrontal cortex in mediating responses to sucrose negative contrast in the rat. Dept. of Physiology, University of California at San Francisco. T.J. van 't Hullenaar (Faculty of Medicine, UvA). Cholesterol in the senile plaque: a clue to the mechanism of secretion of Aβ. Laboratoire Raymond Escourolle, Groupe Hospitalier la Pitié Salpétrière, Paris. A. Klomp (Faculty of Biology, UvA). GABAergic innervation of the hypothalamic paraventricular nucleus in mood disorder: a pilot study. Netherlands Institute for Neuroscience, Amsterdam. S. van Geest (Faculty of Medicine, University of Leiden) Sleep disturbances in Alzheimer's disease. A role for hypocretin-orexin? Dept. Neurophysiology, LUMC, Leiden, and Dept. Neuropsychiatric Diseases. R. van Geel (Faculty of Medicine, UvA) Examination of cerebellar plaques of multiple sclerosis patients with ataxia. Groupe Hospitalier la Pitié Salpétrière, Paris. L. van Wijngaarden (Faculty of Medicine, UvA) Sex differences in the estrogen receptor in the sexually dimorphic nucleus of the preoptic area. 2008 C.A. Croese (Faculty of Medicine, UvA) How does ghrelin increase appetite in the brain? (work experience period supervisor Tony Goldstone, Hammersmith Hospital, Imperial College, London, UK). 34

N. Klioueva (Faculty of Medicine, UvA) Brain Donor Programs in Europe. work experience period Netherlands Brain Bank, supervisor Inge Huitinga). L. Trügg (Faculty of Medicine, UvA) Tracing of the NTS and VGF expression in the NTS in response to feeding and fasting (co-supervised by Ruud Buijs). J. Anink (Faculty of Medicine, UvA) Regulation of CRH expression: crosstalk between ER and AR (cosupervised by J.-N. Zhou). D. Smeekes (University of California at San Francisco, USA) Disrupting GLUR2-AMPAR trafficking in the VTA does not affect behavioral sensitization to cocaine. (co-supervised by Garret Stuber) A. Kuipers (NY State Institute for Basic Research, USA) Study of a chronic treatment with a CNTFbased peptide on a triple transgenic mouse model for Alzheimer's disease. (co-supervised by Julie Blanchard and Inge Grundke-Iqbal). J.W.R. Sins (Cajal-Institute, CSIC, Avenida Doctor Arce 37, E-28002, Madrid, Spain) The antiinflammatory effect of selective estrogen receptor modulators (SERMs), reducing microglia reactivity in vivo after peripheral inflammation: a new perspective in treatment of neurodegenerative diseases? (cosupervised by Prof. L.M. Garcia-Segura). N.W. Duijvis (Faculty of Medicine, UvA) The function of Olig1 in glucocorticoid injury to oligodendrocytes and myelination in the neonatal cerebellum. 2009 A. Huibers (Faculty of Medicine, UvA and Ernest Gallo Clinic and Research Center, University of California, San Francisco, Emeryville, USA) PKCϵ regulates behavioral sensitivity, binding and tolerance to WIN55,212-2. W. Tan (Faculty of Medicine, UvA and University of Illinois at Chicago, USA) Behavioral, physiological and neuroendocrine responses as a function of pup exposure in male prairie voles. F. Wassink (Faculty of Medicine, UvA and University of Illinois at Chicago, USA) J. Ursinus (Faculty of Medicine, UvA) MT 2 melatonin receptor localization in the human hypothalamus and alterations in depression. J. Himmelreich (Faculty of Medicine, UvA). R. Kievit (Faculty of Medicine, UvA, and Universidad de Buenos Aires, Argentina, supervisor Daniel E. Vigo): Autonomic nervous system and decision making. S. van de Bilt (Faculty of Biology, UvA): Neurosteroid biosynthetic enzymes expression: a study on human brain in Alzheimer's and Parkinson's disease. E.F. Hekkelman (Faculty of Medicine, UvA, and Ernest Gallo Clinic & Research Center, UCSF, supervisor Kay M. Tye): DAT blockade mediates the initial cue-reward learning while NET blockade facilitates memory retention of MPH-induced behavioral enhancements. W. van Leeuwen (Faculty of Medicine, UvA, and Ernest Gallo Clinic & Research Center, UCSF, supervisor Garret Stuber): Optogenetic stimulation of basolateral amygdala to nucleus accumbens synapses in mice: a reinforcing effect mediated by D1-type dopamine receptors. A. Koopmans (Faculty of Medicine, UvA, and Ernest Gallo Clinic & Research Center, UCSF, supervisor Dennis R. Sparta): Enhanced corticotropin releasing factor (CRF) signaling in the ventral tegmental area (VTA) following binge drinking is modified by the CRF2 receptor. A. van Lammeren: 'BIID' (24 September). Eindreferaat Psychiatrie. AMC psychiatrisch centrum, Afdeling Stemmingsstoornissen (D.F.Swaab referent). J. Snoek (Faculty of Psychology, UvA, Amsterdam): The visual processing of incentive salience in patients with schizophrenia (Psychiatry, Charité, Berlin, Germany). J. Frijling (Faculty of Medicine, UvA, Amsterdam, University of Illinois at Chicago, USA, with prof. Sue Carter): Autonomic and neuroendocrine effects of acute oxytocin injection. J. van Heusden (Faculty of Medicine, UvA, Amsterdam, University of Illinois at Chicago, USA, with prof. Sue Carter): Estrogen, oxytocin, and anxiety in female prairie voles. 2010 Oostra, A. (Faculty of Medicine, UvA, Amsterdam): Cellular bases for hypocretin-mediated modulation of sleep-wake states within the pontine tegmentum. Hendrikx, R.J. (Faculty of Medicine, UvA, Amsterdam): The primary interoceptive cortex. Prof. F. Torrealba López, Alameda 340, Santiago, Chile. Van Rijn, R. (Faculty of Biology, UvA, Amsterdam): Subventricular nodules and their incidence in Parkinson's disease. Van Alkemade, H. (Faculty of Medicine, UvA, Amsterdam): VEGF secretion in NG2 expressing glioblastoma tumour-initiating cell lines. Jongstra, S. (Faculty of Medicine, UvA, Amsterdam): Dichotic listening and hemispheric lateralization. Terlou, R.J. (Faculty of Medicine, UvA, Amsterdam): Rats acquire strong side preference when raised with fixed bottle position. Lukose, A. (Faculty of Earth and Life Sciences, VU, Amsterdam): Novel insights in Prader-Willi 35

syndrome. SnoRNA HBII-85 gene cluster is a possible candidate gene underlying PWS. Backes, M. (Faculty of Medicine, UvA, Amsterdam and Ernest Gallo Clinic & Research Centre, Department of Neurology, University of California, San Francisco, Emeryville, CA, USA): The role of BDNF in cocaine-induced locomotor sensitization and in a newly set-up mouse cocaine selfadministration model. 2011 Kaag, A.M. (Faculty of??? UvA, Amsterdam): Are all male paedophiles child abusers? Disentangling the behavioural and neurobiological factors that underlie paedophilic sexual preference from those that underlie paedophilic offending. Kroese, C (Faculty of Medicine, UvA, Amsterdam): Skipping breakfast increases brain-activation in reward pathways in response to high-calorie food stimuli. A human functional magnetic resonance imaging study. (with A.P. Goldstone, Imperial College, London, UK, co-supervisor) Ruedi Revilla, N. (José Castilleja project, Spain). Fellowship. Pietersz, K. (Dept. Biosciences, Radboud University Nijmegen): Hypothalamic alterations in depression (with XinRui Qi, Juan Zhao, Ling Shan) Olsman, M. (Faculty of Biology, University of Amsterdam): Causal role of VTA dopamine neurons in associative learning. (with E.E. Steinberg as daily coach) Van Susante, H. (Faculty of Medicine, University of Amsterdam): The role of the arcuate nucleus in the mechanism of corticosterone feedback (with Ruud Buijs of the Instituto de Investigaciones Biomedicas of the Universidad Nacional Autonoma of Mexico. Rigters, S. (Faculty of Medicine, University of Amsterdam): The effects of reduced sleep on autonomic activity and stress in short distance bus drivers. 2012 M. Verbrugge (Faculty of Medicine, University of Amsterdam): The influence of the prefrontal cortex on the ventral tegmental area in mice. (with Jonathan Britt, Gallo Clinic and Research Center, Emeryville, CA, USA) A. Tuenter (Biomedical Sciences, University of Amsterdam): Psychobiological mechanisms of placebo and nocebo effects in antidepressant trials. (with P.J. Lucassen, co-assessor, University of Amsterdam). C. Aarden (Faculty of Medicine, UvA, Amsterdam): Role of Notch signaling and the putative membrane estrogen receptor GPR30 on the neuritogenic action of selective estrogen receptor modulators. (with L.M. Garcia Segura, Instituto Cajal, Madrid, Spain). M. de Brauw (Faculty of Medicine, UvA, Amsterdam): The own, the known and the unknown face: how can we tell the difference? Exploring self-face recognition with event-related potentials. (together with Prof. P. Stoerig and Dr. J. Sänger, Heinrich Heine University, Dusseldorf, Germany). L. de Ruijter (Faculty of Medicine, UvA, Amsterdam): Sexual differences in the response of hypothalamic neurons to muscimol in vitro (together with Dr. H.F. Carrer). For post-academic teaching (Summer and Winter Schools, EMBO courses etc.) see 'International Conferences' University Lectures (and postacademic teaching) 1971 Voordracht `The hypothalamo-neurohypophysial system and reproduction'. 7th Int. Summer School of Brain Research, Amsterdam, 12 augustus. 1972 Voordracht `Invloed van foetale hersenen op intra-uterine groei en baring bij de rat'. Refereeravond Kliniek v. Verloskunde en Gynaecol., Wilhelmina Gasthuis, Amsterdam, 27 november. 1973 Voordracht `The role of the fetal hypothalamus in the development of the fetoplacental unit and in parturition'. 8th Int. Summer School of Brain Research, Baarn, 25-29 juni. 1974 Voordracht `Immunolocalisatie van hypothalamus produkten'. Refereeravond Interne Kliniek, Leiden, 27 februari. 1975 Geïntegreerd college Groei en Ontwikkeling: `Groei en Ontwikkeling van de Hersenen', 3e-jaars Geneeskunde, Univ. v. Amsterdam. 1976 Geïntegreerd college Groei en Ontwikkeling: `Hersenen en groei en groeiende hersenen', 3e-jaars Geneeskunde, Univ. v. Amsterdam. Voordracht `De foetale hypothalamus en hypofyse en het beloop van de baring'. Refereeravond Kliniek voor Verloskunde en Gynaecologie, Wilhelmina Gasthuis, Amsterdam, 26 april. 36

1977 Geïntegreerd college Groei en Ontwikkeling: `Groei en ontwikkeling van de hersenen', 3e-jaars Geneeskunde, Univ. v. Amsterdam. Voordracht `Functional anatomy of the hypothalamus'. Boerhaave-cursus `Clinical and Experimental Aspects of Neuroendocrinolgy', Leiden, 31 maart - 1 april. Voordracht `Fetal neuroendocrine mechanisms in development and parturition'. 10th Int. Summer School of Brain Research, Amsterdam, 11-15 juli. 1978 Voordracht `Role of the pituitary hormones in human parturition'. Boerhaave-cursus `Human parturition; new concepts and developments', Leiden, 27-28 april. 1979 Geïntegreerd college Groei en Ontwikkeling: `Groei en ontwikkeling van de hersenen', 3e-jaars Geneeskunde, Univ. v. Amsterdam, 25 januari. College `Neuro-endocrine besturing van de cyclus', Univ. v. Amsterdam, 5 februari. Voordracht `Morfologische en biochemische veranderingen in de hersenen tijdens veroudering'. Boerhaavecursus `Dementiën', PAO Geneeskunde, Leiden, 15 november. 1980 Geïntegreerd college `Neuroendocrine bestudering van de cyclus', Univ. v. Amsterdam, 22 januari. Geïntegreerd college Groei en Ontwikkeling: `Groei en ontwikkeling van de hersenen, 3e-jaars Geneeskunde, Univ. v. Amsterdam, 24 januari. College `Neuroendocrine regulatie (vasopressine en oxytocine)', 3e-jaars Geneeskunde, Univ. v. Amsterdam, 13 februari. College `Centrale effecten van peptide hormonen', 3e-jaars Geneeskunde, Univ. v. Amsterdam, 13 februari. Inaugurale rede `Bederven wij de hersenen van onze kinderen reeds voor hun geboorte?' bij de aanvaarding van het ambt van buitengewoon hoogleraar in de neurobiologie aan de Universiteit van Amsterdam, 28 april. Voordracht `An approach to specificity in immunocytochemistry (method specificity)'. EMBO-cursus `Immunocytochemistry and its applications in brain research', Amsterdam, 27-30 mei. 1981 Voordracht `Neuropeptides in the limbic system'. ESF Winter School, `Limbic Circuitry and Functions', ETP in Brain and Behavior Research, Zuoz, Zwiterland, 3-10 januari. Geïntegreerde colleges in het kader van de menstruele cyclus, Univ. v. Amsterdam: `Neuroendocrine regulatie van de cyclus', 12 januari, `Organiserende werking geslachtshormonen', 12 januari, `Activerende werking geslachtshormonen', 2 februari. Geïntegreerd college in het kader van de groeicyclus, Universiteit van Amsterdam, 29 januari. Cursus biologische psychiatrie, AMC-Psychiatrie, Amsterdam: `Neurobiologische achtergronden van veroudering en dementie' `Therapeutische (on)mogelijkheden', 19 januari. Voordracht `De invloed van geneesmiddelen op de hersenontwikkeling bij de foet'. Refereeravond Verloskunde en Gynaecol., Wilhelmina Gasthuis, Amsterdam, 23 februari. Voordracht `Neuropeptides and their distribution in the brain', 12th Int. Summer School of Brain Research, `Chemical transmission in the brain', Amsterdam, 31 augustus. College `Enkele stoornissen van de hersenontwikkeling', 3e-jaars Geneeskunde, Univ. v. Amsterdam, 15 oktober. Voordracht `Hersenontwikkeling en de organiserende werking van geslachtshormonen, een introductie'. Vakgroep Interne Geneeskunde, Vrije Univ., Amsterdam, 27 oktober. College `Formation reticularis en monaminerge systemen', 3e-jaars Geneeskunde, Univ. v. Amsterdam, 10 december. 1981/84 Organization Practical course, `Microscopie Centraal Zenuwstelsel' (together with H.B.M. Uylings), 3rd year, Fac. of Medicine. 1982 College `Hersenveroudering, dementie en therapie', Biologische Psychiatrie, AZUA, Amsterdam, 20 januari (2 uur). College `Hersengroei en ontwikkeling' in de groei-cyclus, 3e-jaars Geneeskunde, Univ. v. Amsterdam, 21 januari. Colleges `Neuroendocrine regulatie menstruele cyclus. Activerende effecten geslachtshormonen. Organiserende werking geslachtshormonen', 2e-jaars Geneeskunde, Univ. v. Amsterdam, 26 januari (3 uur). College `Microscopie van het cerebellum', 3e-jaars Geneeskunde, Univ. v. Amsterdam, 4 februari. Colleges `Limbisch systeem' en `Hypothalamus en limbisch systeem', 3e-jaars Geneeskunde, Univ. v. 37

Amsterdam, 11 februari (2 uur). College `Microscopie van de cortex cerebri', 3e-jaars Geneeskunde, Univ. v. Amsterdam, 24 februari. Colleges `Veroudering en dementie', 3e-jaars Geneeskunde, Univ. v. Amsterdam, 15 maart (2 uur). Vasopressin and oxytocin neurons in various stages of life. 2nd EMBO Practical Course `Immunocytochemistry and its Application in Brain Research', Amsterdam, 24-28 mei. De ontwikkeling van het neuron. Academisch Medisch Centrum, Afd. Psychiatrie, Univ. v. Amsterdam, 8 september, 2 uur (PAO Psychiatrie). Peptiderge verbindingen in het centrale zenuwstelsel. Boerhaave cursus, Leiden, 11-12 november. 1983 Neurochemische veranderingen in de hersenen tijdens veroudering en dementie. Amsterdamse Psychiatrie Opleiding, 2e-jaars cursus, Sint Lucas Ziekenhuis, 12 januari, 2 uur (PAO). College `Hersenontwikkeling' in de cyclus `Groei en Ontwikkeling', UvA, 20 januari. College `De hypothalamus en de hypofyse' voor het thema `Menstruele cyclus en levensfasen', UvA, 25 januari. College `Geslachtelijke differentiatie van de hersenen' voor het thema `Menstruele cyclus en levensfasen', UvA, 25 januari. College `Activerende effecten van geslachtshormonen op de hersenen' voor het thema `Menstruele cyclus en levensfasen', UvA, 25 januari. College `Hypothalamus en hypofyse', limbisch systeem, UvA, 28 januari (2 uur). College `Formatio reticularis', UvA, 4 februari. College `Cortex Cerebri', UvA, 11 februari. College `Veroudering en dementie', UvA, 25 februari. (2 uur). College `Cortex Cerebri', UvA, 10 maart. Sexual differentiation of the human brain. A historical perspective. 13th Int. Summer School of Brain Research, Amsterdam, 22 augustus. College `Hersenontwikkeling', post-academische cursus `Psychiatrie', AMC, UvA, 14 sept. (2 uur). Caput college `Het vasopressine neuron', Afdeling Dierfysiologie, UvA, 1 oktober. College `Limbisch systeem', 3e-jaars Geneeskunde, UvA, 3 oktober (2 uur). Inleiding tot het `Hersenpracticum', 3e-jaars Geneeskunde (anatomie), 6 oktober. College `Verslaving en hersenontwikkeling', 2e-jaars Geneeskunde, UvA, 9 oktober. College `Formatio reticularis', 3e-jaars Geneeskunde, UvA, 10 oktober. Inleiding tot het `Hersenpracticum', 3e-jaars Geneeskunde (anatomie), 27 oktober. College `Veroudering en dementie', 2e-jaars Geneeskunde, UvA, 28 oktober (2 uur). College `Microscopie van het cerebellum', 3e-jaars Geneeskunde, UvA, 23 november. 1984 Possibilities and limitations of immunocytochemistry on human postmortem material, ETP Winter School `New developments in the Investigation of the human Brain', Zuoz (Switzerland). 'Neurobiochemische veranderingen in de hersenen tijdens veroudering en dementie' tijdens blok `Organische psychosyndromen', 2e-jaars cursus Amsterdamse Psychiatrie opleiding, St. Lucas Ziekenhuis, PAO Psychiatrie, 4 januari (2 uur). College `Microscopie van de cortex cerebri'. 3e-jaars Geneeskunde, UvA, 25 januari. College `Veroudering en dementie', 3e-jaars Geneeskunde, UvA, 4 april (2 uur). Werkingsmechanisme van chemische teratogenen op de hersenontwikkeling. PAO herhalingscursus `Kindergeneeskunde', RAI, Amsterdam, 9 april. College `Organiserende werking van geslachtshormonen op hersenontwikkeling', 2e-jaars Geneeskunde, Univ. v. Amsterdam, 11 april. College `Activerende werking van geslachtshormonen op hersenontwikkeling', 2e-jaars Geneeskunde, Univ. v. Amsterdam, 11 april. `Hersenontwikkeling en effecten van geneesmiddelen', APO cursus Biologische Psychiatrie, Psychiatrische Kliniek AZA, Academisch Medisch Centrum, Amsterdam, 5 september (2 uur). `Vasopressin and oxytocin neurons in the human brain in relation to aging and dementia', ENA-Satellite Workshop, Boerhaave Course: Modern Techniques in the study of the morphology of the nervous system, Leiden, September 17-18. College 'Hypothalamus en hypofyse', 3e-jaars Geneeskunde (Blok XVIII), Univ. v. Amsterdam, Academisch Medisch Centrum, 1 oktober. College 'Groei en ontwikkeling van de hersenen', 3e-jaars Geneeskunde (Blok XVIII), Univ. v. Amsterdam, Academisch Medisch Centrum, 11 oktober. College 'Veroudering, dementie en geheugen', 2e-jaars Geneeskunde (Blok X), Univ. v. Amsterdam, Academisch Medisch Centrum, (3 sessions) College 'Verslaving en hersenontwikkeling', 2e-jaars Geneeskunde (Blok X), Univ. v. Amsterdam, Academisch 38

Medisch Centrum, 14 november. 1985 Amsterdamse Psychiatrieopleiding. Blok organische psychosyndromen. `Neurobiologische veranderingen in de hersenen tijdens veroudering en dementie', St. Lucas Ziekenhuis, Amsterdam, 30 januari. Caput College `Aging and Dementia', Dierfysiologie, Subf. Biologie, Univ. v. Amsterdam, 5 maart. College `Peptiden in de menselijke hersenen', Faculteit der Geneeskunde, Erasmus Univ., Rotterdam, 6 maart. College onderzoeksstage mogelijkheden voor studenten medische biologie, binnen het programma van het NIH, AMC, 8 mei. Clinical strategies in the treatment of Alzheimer's disease. 14th International Summer School of Brain Research, `Aging of the Brain and Senile Dementia'. Amsterdam, August 30. College `Hypothalamus en hypofyse', Blok XVIII 3e jaar Geneeskunde, UvA, 8 oktober. College `Groei en ontwikkeling van de hersenen', Blok XVIII 3e jaar Geneeskunde, UvA, 10 oktober. College `Limbisch systeem', Blok X 2e jaar Geneeskunde, UvA, 25 & 28 oktober. College `Gebruik toch je hersenen', 39e Universiteitsdag, UvA, 26 oktober. 1986 Wetenschapssymposium `Biologische en psychologische aspecten van dementie', Blok IV 1e jaar Geneeskunde, UvA, Wetenschapssymposium `Biologische en psychologische aspecten van schizofrenie', Blok IV 1e jaar Geneeskunde. College `Leeftijd en circadiane ritmiek' Boerhaave Commissie voor Postacademisch Onderwijs in de Geneeskunde, Univ. van Leiden, 12 juni. Cursus `Neurobiochemische veranderingen in de hersenen tijdens veroudering en dementie' Consortium Psychiatrieopleiding Noord Holland, St. Lucas Ziekenhuis, 13 august. College `Limbisch systeem', Blok X, AMC, 9 oktober. College `Limbisch systeem', Blok X, AMC, 13 oktober. College `Hypothalamus', Blok XVIII, AMC, 20 oktober. College `Hersengroei en ontwikkeling', Blok XVIII, AMC, 30 oktober. College `Verslaving en hersenontwikkeling', Blok Verslaving, Blok X, AMC, 31 oktober 1987 Vrije wil, verantwoordelijkheid en hersenen, MFAS cyclus over Euthanasie, Oude Manhuispoort, Amsterdam, 2 februari Neurobiologische veranderingen tijdens veroudering en dementie, PAO Psychiatrie Consortium Noord-Holland, Valeriuskliniek Amsterdam, 4 februari What may go wrong in brain development due to chemicals? PAO cursus Kindergeneeskunde, AMC, Amsterdam, 11 mei. Geslachtshormonen in relatie tot hersenveroudering en dementie. PAO cursus "Wetenschap en ouder worden". Erasmus Univ. Rotterdam, 15 mei. Potentialities and pitfalls in the use of human brain material in molecular neuroanatomy. ETP/ENA/IBRO Practical Course on Molecular Neuroanatomy, Minisymposium, 18 juni. Postnatal sexual differentiation of the human hypothalamus. 15th Int. Summer School of Brain Research, Amsterdam, 31 augustus. Colleges (4) `Banen', Blok IX, AMC, Amsterdam, 10 & 11 september. Colleges (2) `Limbisch systeem', Blok X, AMC, Amsterdam, 19 september. College `Hypothalamus', Blok XVIII, AMC, Amsterdam, 19 september. College `Verslaving van de moeder en hersenontwikkeling van het kind, Blok X, AMC, Amsterdam, 27 oktober. 1988 Cursus macroscopische neuroanatomie voor NIH-medewerkers, 4 sessies, februari en maart. Bederven wij de hersenen van onze kinderen reeds voor de geboorte? Boerhaave Commissie voor Postacademisch Onderwijs in de Geneeskunde. Op de grens van kinderneurologie en kinderpsychiatrie, Leiden, 29 april. College `Hypothalamus', Blok XVI, geneeskunde AMC, Amsterdam, 16 mei. College `Limbisch Systeem', Blok X, geneeskunde AMC, Amsterdam, 24 oktober. College `Body, mind and gender', Blok X, geneeskunde AMC, Amsterdam, te zamen met Prof.dr. F. de Jonghe, 24 oktober. College (minisymposium `Biologische kennis van homosexualiteit'), Blok X, geneeskunde AMC, Amsterdam, 24 oktober. College `Verslaving van de moeder en hersenontwikkeling', Blok X, geneeskunde AMC, Amsterdam, 11 november. College `Brain disturbances in the elderly', Postgraduate course on `Drug development and aging', Center for Bio- Pharmaceutical Sciences, Leiden, 10 november. 1989 Cursus Organische Stoornissen, Consortium Psychiatrie Noord-Holland, Neurobiologsche aspecten van 39

veroudering of dementie, 2 uur, Psychiatrie AMC, Amsterdam, 1 februari. Organisatie en leiding AIO-dag `De hersenen in gevaar tijdens zwangerschap en baring', Ned. Inst. v. Hersenonderzoek, 10 februari. `De betrokkenheid van de moederlijke en foetale hersenen bij de ontwikkeling en baring', AIO-dag, Ned. Inst. v. Hersenonderzoek, 10 februari. 'De Hypothalamus', Blok XVIII, Geneeskunde AMC, Amsterdam, 29 mei 'Body-mind problematiek en blok X'. Geneeskunde, 2 e jaar, 3 uur (samen met andere docenten), 9/10/89, AMC. 'Limbische systeem', blok X, Geneeskunde 2 e jaar, 12/10/89, AMC. Symposium 'Homosexualiteit', blok X, Geneeskunde, 3 uur (samen met andere docenten), 20/10/89, AMC. College `Verslaving van de moeder en hersenontwikkeling van het kind', Blok X, geneeskunde, 2 e jaar, 31/10/89, AMC. 1990 Organisatie AIO-dag over Neurodegeneratieve ziekten, Neurowetenschappen Amsterdam, together with Prof.dr. J.M.B.V. de Jong, 28 maart, NIH, Amsterdam Caput College 'Plasticiteit van het Zenuwstelsel', Neurowetenschappen Amsterdam. Influence of Hormones on Brain Development. 28 mei, NIH, Amsterdam College 'Hypothalamus'. Blok XVIII, AMC, 21 mei, Amsterdam. Organisatie AIO-dag Neurowetenschappen Amsterdam, 'Limbisch systeem en gedrag', 28 september, NIH, Amsterdam, met C.J.C. Boersma, A.B. Dessens en R. de Beun. College, inleiding blok X, biologische aspecten (met andere docenten, 3 uur) geneeskunde 2e jaar, 8 oktober, AMC, Amsterdam College, limbisch systeem, blok X, geneeskunde 2e jaar, 11 oktober, AMC, Amsterdam College, symposium sexeverschillen, blok X, biologische aspecten, 3 uur te zamen met andere docenten, 19 oktober, AMC, Amsterdam Gastcollege VU, Faculteit Biologie, cursus voortplanting, ontwikkeling en veroudering 'maatschappelijke aspecten van het onderzoek over sexuele differentiatie', 23 oktober, VU, Amsterdam College, verslaving van de moeder en de hersenontwikkeling van het kind, blok X, geneeskunde 2e jaar, 30 oktober, AMC, Amsterdam Neuropeptiden, CREA, studium generale UvA, 14 november, Amsterdam 1991 Neurobiologische aspecten van veroudering en dementie. Consortium psychiatrie opleiding Noord Holland, Cursus Organisatie Stoornissen St. Lucas Ziekenhuis, Amsterdam 16 januari 1991. Differentiation of the human hypothalamus in relation to gender and sexual orientation. 17th International Summer School of Brain Research. Aula van de universiteit van Amsterdam, 28 augustus 1991. 1992 AIO-cursus Endocrinologie 'Geslachtshormonen en hersenontwikkeling bij de mens', 28 februari 1992, Vrije Universiteit Amsterdam. Praktische cursus 'Macroscopische Neuroanatomie voor AIO's e.a. Zes middagen 11 februari-16 maart. 1992 Inleiding "Neurodegenerative Diseases'. AIO-dag "Neuroendocrinology and Neurodegenerative Diseases, 3 april 1992. Inleiding tot de Neuroanatomie Blok 13 (werking van het zenuwstelsel) 20-10-1992, Academisch Medisch Centrum, Amsterdam. Neurobiologische aspecten van de ziekte van Alzheimer. Student symposium 'Het Brein in Stukken'. Tropeninstituut, Amsterdam, 11 November 1992. Neurologie versus psychiatrie (inleiding blok XIV), 7 december 1992 Limbisch systeem en depressie, Blok XIV, 16 december 1992 Limbisch systeem: sexuele differentiatie van de hersenen, Blok XIV, 16 december 1992 1993 Invloed alcohol, tabak, drugs op ontwikkeling hersenen, Blok XIV, 20 januari 1993 Neuroanatomie van schizofrenie, autisme, anorexia nervosa en bulimie, Blok XIV, 26 januari 1993 Neuroanatomie van het geheugen, Blok XIV, 27 januari 1993 Seminar voor AIO's over 'Morfometrie en de menselijke hersenen' voor 'De Grijze Massa'. Rudolf Magnus Instituut, Utrecht, 15 februari 1993 Lezing "Alzheimer-Dementie, morfologie", Post Academisch Onderwijs Geneeskunde over Parkinson & Dementie, Dr. G.J. van Hoytema Stichting, Universiteit van Twente, 23 april 1993. Introductie AIO-dag Neurowetenschappen: "Development till death & aging from conception", Amsterdam, 28 april 1993: Boerhaave course De Biologische Klok; Praktische toepassingen in kliniek en huisartsenpraktijk. Development and 40

aging of the biological clock. 7-8 October 1993. Introductie Blok 13 (Neurologie) 3e jaar Geneeskunde UvA (AMC), 18 October. Studium Generale, University of Maastricht, Seksuele differentiatie van onze hersenen, 17 November. Blok 14, 3e jaar Geneeskunde UvA (AMC): Inleiding Psychiatrie versus neurologie (Neurologische aspecten van psychisch functioneren), 6 December. Neurobiologische aspecten van ontwikkelingsstoornissen, 7 December. Neurobiologie van depressie, 14 December. Neurobiologie van sexuele differentiatie, 15 December. Sexual differentiation of the human hypothalamus, college in het kader van "Hormonale beïnvloeding van het zenuwstelsel" voor het AIO netwerk Wageningen, 13 December 1993. 1994 Blok 14, 3e jaar geneeskunde AMC 12/1/1994, Psychosen en gedragsstoornissen; 18/1/1994, Verslaving AIO cursus Neurowetenschappen voor gevorderden (NWA) coördinator module 4 Alzheimer's disease (NIBR, Amsterdam, 26 January 1994). Introduction Alzheimer's disease Theories on aetiology and pathogenesis of Alzheimer's disease. "De relatie tussen structuur en functie van de hersenen van de mens" Symposium "Hersenen, 't verstand te boven" (Utrecht, 21 Feb. 1994). Controversies in the Neurosciences (NWA), (AMC, Amsterdam, 9 June 1994): D.F. Swaab en E.R. de Kloet 'Corticosteroid neurotoxiciteit staat centraal in het pathogenetisch mechanisme van de ziekte van Alzheimer'. 4 university lectures for the "Zwaartepunt onderwijs Neuroinstituut", Faculty of Medicine, "The Research Programme of the NIBR" (Amsterdam 8 and 10 June 1994). Lecture on Plasticity and Aging for the 1994 European Summerschool on Cognitive Neuroscience, Berg en Dal, 27 June 1994. 4 university lectures for the "Zwaartepunt onderwijs Neuroinstituut", Faculty of Medicine, "The Research Programme of the NIBR" (Amsterdam, 14 and 16 September 1994). Introduction to Neurology, 17 October 1994. Blok 13. The Nervous System, AMC, UvA. Introduction to Blok 14. 5 December 1994. The artificial difference between neurology and psychiatry. AMC, UvA Neurobiological aspects of developmental disturbances. Blok 14, 13 December 1994, AMC, UvA. Neurobiological aspects of sexual behaviour. Blok 14. 14 December 1994, AMC, UvA. Neurobiological aspects of psychoses and disturbed behavior. Blok 14. 21 December 1994, AMC, UvA. 1995 Neurobiological aspects of addiction. Blok 14. 17 January 1995, AMC, UvA. AIO cursus, "Theories on etiology and pathogenesis", 8 February 1995. AIO cursus, "Neuropathological examination of microscopic preparations", together with W. Kamphorst. 10 February 1995. Sexuele differentiatie van de menselijke hersenen. Gyrinus natans, 5 April 1995, Vrije Universiteit, Amsterdam. Neurobiology of dementias - MIK module 12, AMC, 13/6/1995 Neurology versus psychiatry - MIK module 12, AMC 14/6/1995 Neurobiology of schizophrenia, autism, anorexia nervosa and bulimia - MIK module 12, AMC, 14/6/1995 Neurobiology of addiction - MIK module 12, AMC, 20/6/1995 Neurobiology of depression - MIK module 12, AMC, 7/7/1995 Hersenonderzoek en transsexualiteit MFAS - onderwijsdag symposium Transsexualiteit, 14 november 1995, UvA, AMC. Neurobiologische aspecten van psychisch functioneren, 4 december 1995, UvA, AMC. Neurobiologie van ontwikkelingsstoornissen, 5 december 1995, UvA, AMC. Neurobiologie van depressie, 12 december 1995, UvA, AMC. Neurobiologie van eetstoornissen, 19 december 1995, UvA, AMC. Neurobiologie van psychosen, 20 december 1995, UvA, AMC. Cursus ED 223 Pathofysiologie van het zenuwstelsel, Biologie, UvA 21 december 1995. College ziekte van Alzheimer en Practicum Neuropathologie. 1996 Neurobiologie van de verslaving, 16 januari 1996, UvA, NIH: De ziekte van Alzheimer en andere neurodegeneratieve ziekten, met microscopisch praktikum neuropathologie. Neuronale netwerken en klinische neurologie i.h.k. van een extra college Neurologie, 24 januari 1996, UvA, AMC. Practical course in Neuroscience "Neuropathology of Alzheimer's disease, Parkinson's disease and Multiple Sclerosis" (together with W. Kamphorst) NIBR, 23-2-1996, Amsterdam MIK lectures (module 12, klinische concepten): Neurobiological aspects of dementia (4 June) 41

Neurobiological aspects: psychoses (5 June) Neurobiological aspects: autism/anorexia nervosa (5 June) Neurobiological aspects: addiction (11 June) Neuropathologie: pathologie van de hypothalamus (14 June) 5th Amsterdam Summer course Diagnostic Pathology: Neuropathology 12-14 June 1996, AMC, Amsterdam Neurobiological aspects: depression (25 June) Neuroanatomy (introduction) Blok 13, AMC (14 October) Het Raadsel van Hersenen en Gedrag (in het kader van het programma het raadsel als begin en einde in de wetenschap ). CREA, UvA (6 November) Swaab, D.F. - Neuropathology of the human hypothalamus. Summer School AMC (Pathology Department). Swaab, D.F. - De ontwikkeling van de hersenen en de geslachtsdifferentiatie. Werkgroep seksuologische hulpverlening in het AZG. Nascholing. Seksuologie in vogelvlucht, 15 November 1996. College Introductie in de Neuroanatomie (Localisatie van laesie tot puntmutatie) 15 okt. 1996, Blok 13, AMC. Neurologie versus Psychiatrie. Introductiecollege, 2 dec. 1996, Blok 14, AMC. Ontwikkelingsstoornissen en functionele teratologie, 3 dec. 1996, Blok 14, AMC Masterclass. 2 Colleges over sexuele differentiatie van de hersenen, 10 dec. 1996, Blok 14, NIH. Neurobiologie van Psychosen, 11 dec. 1996, Blok 14, AMC. 1997 College verslaving, 14 jan. 1997, Blok 14, AMC. Symposium eetstoornissen (geïntegreerde colleges: 4 uur). Blok 14, AMC. AIO cursus ONWA Clinical Neurosciences and Neuropathology (NIBR, Amsterdam): Theories on etiology and pathogenesis. Neuropathological examination of microscopic preparations (with Dr. W. Kamphorst). Masterclass debate between D.F. Swaab and J.A. Swinkels. 12 June, Scheltema, Holkema, Vermeulen, Amsterdam. Will there still be neurology and psychiatry after the year 2000? (in Dutch). Circadiane en circannuale ritmes in depressie, veroudering en dementie (Psychiatrisch Centrum Bloemendaal, Den Haag). Ten behoeve van de artsassistenten in opleiding tot psychiater en klinisch geriater (30/10/97). 5 colleges MIK (module 11), AMC 2-9-1997 Neurobiologische aspecten van dementie 9-9-1997 Neurobiologische aspecten van verslaving 9-9-1997 Neurobiologische aspecten van depressie 11-9-1997 Neurobiologische aspecten van psychosen en autisme 11-9-1997 Neurobiologische aspecten van eetstoornissen 20th International Summer School of Brain Research (Neuronal Degeneration and Regeneration, Amsterdam, 5-29 August). Reduced neuronal activity in Alzheimer s disease and strategies of reactivation. Masterclass Professor Nancy C. Andreasen. AMC. Member of the selection committee. 6 colleges blok 14 (Geneeskunde), AMC 1-12-1997 Neurobiologische aspecten van psychisch functioneren 2-12-1997 Neurobiologische aspecten van ontwikkelingsstoornissen 10-12-1997 Neurobiologie van psychosen 13-12-1997 Neurobiologie van eetstoornissen 16-12-1997 Neurobiologie van depressie (met W.J.G. Hoogendijk) 21-12-1997 Symposium Verslaving. 13.00-16.00 uur. Cursusdag Biologie UvA - medische biologie 19/12/97 Nederlandse Hersenbank college Practicum neurodegeneratieve ziekten, 2 hours 1998 3-1-98 College Eetstoornissen blok 14 (AMC) 21-1-98 Symposium Verslaving blok 14 (AMC, 4 hours, integrated teaching) 30-1-98: AIO course ONWA; theories on etiology and pathogenesis of AD. 30-1-98: Practical course Neuropathology, with Dr. W. Kamphorst. 24-3-98: Master course Biologie van de Hersenen, Leer en Geheugenstoornissen for Biology teachers, Faculty of Biology, UvA 2-5 June 98: Annual Science Week for second-year students of Medicine of the UvA: 4 afternoons with 12 students for NIBR and NBB. Together with Dr. R.W.H. Verwer. September: Guest lectures at Anhui Medical University, Hefei, Anhui, PR China. On: Development, sexual differentiation, diabetes insipidus, eating disorders, depression, aging. and dementia. Colleges MIK, Module 11 (Klinische concepten 4: zenuwstelsel): 08-09-1998 Neurobiologische aspecten van dementie 42

17-09-1998 Neurobiologische aspecten: psychosen en autisme 17-09-1998 Neurobiologische aspecten: anorexia nervosa en andere eetstoornissen 12-10-1998 Neurobiologie van de verslaving 12-10-1998 Neurobiologische aspecten: depressie Selection committee of the Masterclass for Prof. Charles Weissmann, with W.A. van Gool and P. Borst. November 5, 1998. Colleges Blok 15 (Psychisch functioneren) 7-12-1998 Wat is het verschil tussen neurologie en psychiatrie 8-12-1998 (9-12.45) Symposium stemmingsstoornissen inclusief college De neurobiologie van depressie. 15-12-1998 De neurobiologie van schizofrenie en autisme 16-12-1998 De neurobiologie van ontwikkelingsstoornissen 1999 13-1-1999 De neurobiologie van eetstoornissen - blok 15 22-1-1999 De neurobiologie van verslaving - blok 15 25-2-1999 AIO cursus Possible pathogenetical mechanisms in Alzheimer, AMC 25-2-1999 Practical AIO course (with R. Ravid and W. Kamphorst) of 2 hours MIK courses (module 11) AMC 7-9-1999 - Neurobiologische aspecten van dementie 15-9-1999 (double) - Neurobiologische aspecten: psychosen/autisme/anorexia nervosa 30-9-1999 - Neurobiologische aspecten 11-10-1999 - Neurobiologie van de verslaving Organized 1 day of the AIO-course Macroscopische, microscopische en pathologische anatomie van de huismuis, 11-15 October 1999: Neuroanatomie van de muis. Introduction: neuroanatomie van de muis Macroscopische en microscopische anatomie van de hersenen. Guest Professor Capital University of Beijing, Beijing, P.R. China, 15 October 1999 Life span functions of the biological clock and the therapeutical value of light. Life and death in the central nervous system. Guest Professor Anhui Medical University, Hefei, Anhui, P.R. China, 18 October 1999 Brain research from the moment of birth to the moment of death Human brain disection (3 hours) The relationship between the prefrontal cortex and the hypothalamus in the pathogenesis of depression. Is there life after brain death? (University of Science and Technology of China, Hefei, China) APO Psychiatry courses (coordination D.F. Swaab) 16 hrs Sexual differentiation of the brain (in Dutch) The neurobiology of depression (in Dutch) The neurobiology of eating disorders (in Dutch) The neurobiology of schizophrenia (in Dutch) Is there life after (brain) death? (in Dutch) Blok 15 Psychisch Functioneren (AMC) Neurobiologische aspecten van psychisch functioneren Neurobiologie van depressie Neurobiologie van psychosen Neurobiologie van de ontwikkelingsstoornissen 2000 Blok 15 Psychisch Functioneren (AMC) Neurobiologie van eetstoornissen Angststoornissen AIO course Neurosciences Amsterdam Pathogenetic theories and possible therapies for Alzheimer s disease Pathogenetic theories and possible therapies for Alzheimer s disease. Cognition and Emotion, Part III, Schizophrenia & Alzheimer s disease. NIBR, 14 February (AIO course ONWA) Neuropathology practicals (2.5 hours). With Dr. W. Kamphorst and Dr. R. Ravid. Cognition and Emotion, Part III, Schizophrenia & Alzheimer s disease. NIBR, 14 February (AIO course ONWA) Geslachtsverschillen in hersenen en gedrag, -wetenschappen en samenleving. Gorlaeus Laboratoria, Fac. Wiskunde en Natuurwetenschappen, Univ. Leiden, 8 March Coördinatie APO onderwijs Psychiatrie. 14 hrs (AMC) Wetenschapsweek (4-8 September) 43

3 rd year medicine students AMC, 2 days on Alzheimer s disease. Organized with R.W.H. Verwer. MIK courses (AMC, Amsterdam) 5/9 Neurobiologie van dementieën 14/9 Neurobiologie van schizofrenie en autisme 14/9 Neurobiologie van eetstoornissen 28/9 Neurobiologie van depressie 9/10 Neurobiologie van verslaving Blok 15 (AMC, medicine) 4/12 Neurobiologische aspecten van psychisch functioneren 5/12 De neurobiologie van schizofrenie (symposium psychische stoornissen) 6/12 Neurobiologie van depressie 13/12 Neurobiologie van de ontwikkelingsstoornissen 20/12 Neurobiologie van eetstoornissen Studium Generale Universiteit Groningen. Lecture on "Sexual differentiation of our brains and behavior." (14/11/00) Postgraduate education course. Dept. Psychiatry, AMC Hypothalame aansturing lichamelijke functies (eetstoornissen) 27/9/00 Verslaving 27/9/00 Food disorders (22-12/2000) 2001 Postgraduate education course. Dept. Psychiatry, AMC Sexual differentiation of the brain (3/1/2001) Anxiety (3/1/2001) Practical Neuroanatomy (3/1/2001) The neurobiology of schizofrenia (14/2/2001) Blok 15 AMC (medicine) Neurobiology and addiction (16 January 2001) Coordinator of APO (postgraduate course in Psychiatry, AMC): Sexuele differentiatie van de hersenen: gender, sexuele oriëntatie en psychopathologische consequenties. Advanced course in Neurosciences (ONWA-aio s): 20 Feb. 9.15-10: Pathogenetic mechanisms in Alzheimer's disease and Neuropathology, practical tutorial (with R. Ravid and W. Kamphorst). APO onderwijs psychiatrie (coördinatie neurobiologie): 13-06-01: Neurologie versus Psychiatrie Practicum Neuroanatomie 20-06-01: Leven na de dood. 26-09-01: APO cursus Psychiatrie AMC: Neurobiologie van verslaving Neurobiologie van eetstoornissen 19-12-01: APO cursus psychiatrie AMC: Sexuele differentiatie van de hersenen Neuroanatomie (practicum) Onderwijs psychiatrie, geneeskunde, AMC, blok 15: 4-12-01: Neurobiologische aspecten van psychisch functioneren 5-12-01: Neurobiologie van depressie 7-12-01: Neurobiologie van psychosen 19-12-01: Neurobiologie van eetstoornissen Capita Selecta Neurosciences: APO onderwijs Psychiatrie. Hersendood. 21 March., AMC Chairman The Amsterdam International Medical Summer School, Bridging Neurology and Psychiatry. Dementia, Depression, Schizophrenia and Addiction, AMC, 15-28 July 2001 Introductory speech Introduction to the scientific program Neuroanatomy (computer-assisted and anatomical preparations) Functional neuroanatomy of the human hypothalamus (partly computer-assisted). Neurobiology of depression. 22 nd International Summer School of Brain Research, Amsterdam, 20-24 August 2001: Introduction Introduction to the C.U. Ariëns Kappers lecture. Brain aging and Alzheimer s disease: use it or lose it. (22 August 2001) Sexuale differentiatie van de hersenen: gender, sexuele oriëntatie en psychopathologische consequenties. Subvereniging Assistenten Psychiatrie der Nederlandse Vereniging voor Psychiatrie. Utrecht, 18 May 2001 44

MIK module 14, AMC Neurobiologische aspecten van depressie Neurobiologische aspecten van psychose Neurobiologische aspecten van verslaving AMC Science Education Programme. We are our brain, 10 December 2001. AMC 2002 Blok 15, Medicine, AMC 15-01-02: Neurobiologie en verslaving 02-12-02: Neurobiologische aspecten van psychisch functioneren 06-12-02: Neurobiologie van psychosen 10-12-02: Neurobiologie van de ontwikkelingsstoornissen 17-12-02: Neurobiologie van eetstoornissen AIO course. Pathogenetic mechanisms of Alzheimer s disease (20-02-02)/AIO cursus 20/02/02 (ONWA) Practical course 21/02/02: The use of human brain material for research purposes and the Netherlands Brain Bank. APO onderwijs Psychiatrie (coördinatie Neurobiologie), AMC 03/01/02/APO course Psychiatry Is er leven na de hersendood? De Nederlandse Hersenbank Neurobiologie van eetstoornissen/verslaving (2 hours) 24/04/02 Is er leven na de hersendood? 15-05-02 Neurobiologie van schizophrenie. 29-05-02 Seksuele differentiatie van de hersenen. 05-06-02 Practicum Neuroanatomie. 05-06-02 11/04/02 Herhalingscursus kindergeneeskunde AMC. De invloed van geslachtshormonen op de hersenontwikkeling. Principles of Neuroscience. Course organized by the Graduate School Neurosciences Amsterdam and the Graduate School Pathophysiology of the Nervous System Utrecht. Pathogenetic mechanisms of Alzheimer s disease, 20 februari. The use of human brain for research purposes and the Netherlands Brain Bank. Together with R.W.H. Verwer and R. Ravid, 21 februari Studium Generale Universiteit Leiden ism Faculteit Godgeleerdheid Universiteit Leiden: Hersenen, bewustzijn en geloof: Neurobiologische aspecten.: Religie in de academische arena. Leiden, 18 februari 2002. MIK module 14, AMC Neurobiologische aspecten depressie. 22 november 2002 Neurobiologische aspecten van psychose. 25 november 2002 Neurobiologische aspecten verslaving. 28 november 2002 Wetenschapsweek, AMC Spanning tussen maatschappij, geneeskunde en de wetenschap. 7 oktober 2002 Workshop Principles of Neuroscience (Graduate School Neurosciences Amsterdam and Graduate School Pathophysiology of the Nervous System Utrecht. Pathogenetic mechanisms of Alzheimer s disease. 20 February 2002 PAOG herhalingscursus Kindergeneeskunde. Vrije Universiteit, 11 oktober 2002 Hersenen, bewustzijn en geloof: neurobiologische aspecten. Lezingenserie: Religie in de academische arena. Studium Generale Universiteit Leiden i.s.m. Faculteit der Godgeleerdheid. 18 februari 2002. AGIO course Psychiatry AMC 12/02/02 Sexual differentiation of the brain. Practical course neuroanatomy 2003 Workshop: Gedrag in alle soorten en maten van kinderen in alle soorten en maten: Crimineel gedrag en hersenen. MFAS congres: Kinderart(s). De kunst van het genezen van het zieke kind. 29 January 2003. Dementia. Principles of Neuroscience. Graduate School Neurosciences Amsterdam and Graduate School Pathophysiology of the Nervous System Utrecht. 19 February 2003. Blok 15, Medicine, AMC 14-01-03 Neurobiologie en verslaving AGIO course Psychiatry AMC 22/01/03 Eating disorders, addiction 29/01/03 Life/Death. Netherlands Brain Bank 05/02/03 Schizophrenia 12-03-03 Hersenen, Bewustzijn en Religie. Biologische studentenvereniging, University of Nijmegen 07-05-03 Is er leven na de hersendood? De Nederlandse Hersenbank 25-06-03 Seksuele differentiatie van de hersenen. Practicum Neuroanatomie. 45

APO courses Psychiatry: Neurobiologie van eetstoornissen/verslaving, 23 April, AMC Neurobiologie van verslaving, 23 April, AMC Is er leven na de hersendood? 7 May, AMC Schizofrenie, 28 May, AMC Seksuele differentiatie van de hersenen, 25 June, AMC Practicum Neuroanatomie, 25 June, AMC Seksuele differentiatie van de hersenen, 17 December, AMC Practicum Neuroanatomie, 17 December, AMC MIK Courses, AMC Neurobiologische aspecten: depressie, 21 November, 12.3-13.15. Neurobiologische aspecten: psychose, 24 November, 13.00-13.45 Neurobiologische aspecten: verslaving, 27 November, 10.0-10.45 2004 Blok XV Psychiatrie, Geneeskunde, AMC Eetstoornissen, 14 January, AMC Verslaving, 27 January, AMC APO course Psychiatry Schizofrenie, 21 January, AMC Verslaving, 28 January, AMC Eetstoornissen, 28 January, AMC Is er Leven na de Dood, 4 February, AMC Schizofrenie, 2 juni, AMC Neurobiologie van eetstoornissen, 9 juni, AMC Neurobiologie van verslaving, 9 juni, AMC Is er Leven na de Dood, 16 juni, AMC Seksuele differentiatie van de hersenen, 23 juni, AMC Practicum Neuroanatomie, 23 juni, AMC 20/2 ONWA PhD course Dementia. Free University. 26/10 Studium Generale Cyclus Sociale Wetenschappen, Universiteit van Utrecht. Alleen Hersenen. Academiegebouw Universiteit van Utrecht. 17/11 Neurobiologische aspecten van depressie. Medische Informatiekunde (MIK) course, UvA 29/11 Neurobiologische aspecten van psychose. Medische Informatiekunde (MIK) course, UvA 02/12 Neurobiologische aspecten van verslaving. Medische Informatiekunde (MIK) course, UvA 06/12 Neurobiologische aspecten van psychiatrische stoornissen. Onderwijs Blok 15, UvA 07/12 Neurobiologische aspecten van ontwikkelingsstoornissen. Onderwijs Blok 15, UvA 15/12 Neurobiologie van psychosen. Onderwijs Blok 15, UvA 21/12 Neurobiologie van depressie. Onderwijs Blok 15, UvA 16/12 Two lectures for the Swammerdam Institute of Life Sciences (SILS), UvA, on the relationship between structure and function in the brain. Brain development Brain diseases in adulthood and aging 26-10-04 Alleen hersenen. Studium Generale cyclus Sociale Wetenschappen, Universiteit van Utrecht. Het kind als spiegel van de beschaving. 2005 APO Onderwijs Psychiatrie (coördinatie Neurobiologie) 05/01 Is er leven na de hersendood? 05/01 De Nederlandse Hersenbank 12/01 Schizofrenie 19/01 Neurobiologie van eetstoornissen/verslaving 02/02 Seksuele differentiatie van de hersenen Practicum Neuroanatomie 11/05 Schizofrenie 08/06 Neurobiologie van eetstoornissen Neurobiologie van verslaving 15/06 Is er leven na de hersendood? De Nederlandse Hersenbank 22/06 Seksuele differentiatie van de hersenen 46

Practicum Neuroanatomie 26/01 De neurobiologie van agressie. Symposium Blok 15, Agressie, een psychiatrisch probleem? Biologische, psychologische, sociale en ontwikkelingsaspecten van agressie. 02/02 MFAS Congresdag 2005 Bio-psychologische kant van transseksualiteit en homoseksualiteit. 22-09-05 Neurodegenerative disorders, Symposium Staying Alive, X-Track, Megaron Educatorium, University of Utrecht. 11-10-05 Amsterdam-China Symposium. Masterclass Neurosciences, Netherlands Institute for Brain Research 12-10-05 Amsterdam-China Symposium. Public Debate, 12-10-05, Academic Medical Center (AMC), Amsterdam 10-10-05 Amsterdam-China Symposium. The human circadian system in neurological and psychiatric disorders. Academic Medical Center (AMC) Amsterdam, 10-10-05 Wetenschapsweek 12-10-05 Spanning tussen maatschappij, geneeskunde en de wetenschap. Wetenschapsweek, Academic Medical Center (AMC). 29-11-05 D.F. Swaab. Neuropsychiatric diseases, Netherlands Institute for Brain Research, ONWA Introduction course. University Lectures Blok 15 Medicine AMC 05-12-05 Neurobiologische aspecten van psychiatrische stoornissen 06-12-05 Neurobiologische aspecten van ontwikkelingsstoornissen 14-12-05 Neurobiologie van psychosen 20-12-05 Neurobiologie van depressie 2006 University Lectures Blok 15 Medicine AMC 18-01-06 Neurobiologie van eetstoornissen 24-01-06 Neurobiologie en verslaving 25-01-06 Neurobiologie van placeboeffecten 04-12-06 Neurobiologische aspecten van psychiatrische stoornissen 05-12-06 Neurobiologische aspecten van ontwikkelingsstoornissen 13-12-06 Neurobiologie van psychosen 19-12-06 Neurobiologie van depressie 01-02-06 De Maakbare Mens ("Extreme Evolution Makeover"). M-Fas Congresdag Lezing: Het maakbare brein APO-onderwijs Psychiatrie AMC 11-01-06 Neurobiologie van eetstoornissen 11-01-06 Neurobiologie van verslaving 18-01-06 Schizofrenie 01-02-06 Is er leven na de hersendood? 01-02-06 De Nederlandse Hersenbank 08-02-06 Seksuele differentiatie van de hersenen. Practicum Neuroanatomie 13-12-06 Hersenontwikkeling en functionele teratologie 04-03-06 Sex differences in the brain and gender. 16 th Med. Interfac. Congres (Delft). Organisatie "Symposium for Students of Movement Sciences", Groningen (with Prof. dr. E.J.A. Scherder) 10-03-06 De Nederlandse Hersenbank: leven na de dood. 20-04-06 Seksuele differentiatie. Voor studenten biologie, biomedische wetenschappen en psychobiologie UvA. NIN, Amsterdam 28-04-06 Seksuele differentiatie. Voor studenten neuropsychologie, Universiteit Twente. NIN, Amsterdam 10-05-06 Het menselijk karakter als ontwikkelingsstoornis. Cursusprogramma Landelijk Onderwijs Kinder- en Jeugdpsychiatrie, Den Dolder 18-05-06 Seksuele differentiatie van de hersenen van de mens. Gastcollege Leidse Biologenclub, Leiden. 09-10-06 Spanning tussen maatschappij, geneeskunde en de wetenschap. Wetenschapsweek 2006, AMC, Amsterdam 09-11-06 Nascholingscursus voor psychiaters "Achter de Schermen", georganiseerd door Mark Two Communications en het NIN. Het karakter als aangeboren afwijking. Lezing Dick Swaab: Het menselijk karakter als ontwikkelingsstoornis 2007 Cursusprogramma Landelijk Onderwijs Kinder- en Jeugdpsychiatrie, Tulip Inn De Veluwe, Beekbergen. 09-05-07 Het menselijk karakter als ontwikkelingsstoornis. APO-onderwijs Psychiatrie AMC 47

Schizofrenie Neurobiologie van eetstoornissen/verslaving Is er leven na de hersendood? De Nederlandse Hersenbank Seksuele differentiatie van de hersenen Practicum Neuroanatomie Our character as inborn error. Biologen Symposium Communication in Biology, De Rode Hoed, Amsterdam Parkinson & Alzheimer. Symposium for Students of Movement Sciences, Groningen, held in the NIN (with Prof. dr. E.J.A. Scherder). Het menselijk karakter als ontwikkelingsstoornis. Cursusprogramma Landelijk Onderwijs Kinder- en Jeugdpsychiatrie, Tulip Inn De Veluwe, Beekbergen. Neuropsychiatric diseases. AIO introductie cursus, NIN. University Lectures Blok 15 Medicine AMC 17-01-07 Neurobiologische aspecten van eetstoornissen 22-01-07 Neurobiologie en verslaving 23-01-07 Het placebo-effect: het onbewust zelf-helende vermogen van de hersenen. Symposium Blok 15: Placebo s en het placebo-effect. 03-12-07 Neurobiologische aspecten van psychiatrische stoornissen 04-12-07 Neurobiologische aspecten van ontwikkelingsstoornissen 12-12-07 Neurobiologie van psychosen 18-12-07 Neurobiologie van depressie Medical Neurosciences and Neuro-anatomy College Master Neuroscience at the Vrije Universiteit 27-09-07 The human hypothalamus Wetenschapsweek 09-10-07 Spanning tussen maatschappij, geneeskunde en de wetenschap. AMC AIO introduction course 21-11-07 Neuropsychiatric diseases 2008 University Lectures Blok 15 Medicine AMC 16-01-08 Neurobiologie van eetstoornissen 22-01-08 Neurobiologie en verslaving 23-01-08 Neurobiologie van placebo's. HC 11: Symposium. Het placebo-effect: het onbewust zelf-helende vermogen van de hersenen. 2 Gastcolleges Rechtsgeleerdheid (vak: Conflictbeheersing) 25-02-08 De determinanten van ons handelen en de Vrije Wil (Oudemannenhuispoort, UvA) Achter de Schermen (nascholingscursus voor psychiaters). NIN 27-03-08 Het karakter als aangeboren afwijking Depressie en de hypothalamus Medical Neurosciences and Neuroanatomy Class Master Neuroscience at the Vrije Universiteit (host: Prof. dr. E.J.A. Scherder) 26-09-08. "The Human Hypothalamus". 04-12-08. 2 guest lectures "Ons karakter als aangeboren afwijking" (UvA) Open Forumdiscussie 11-12-08. Wetenschappers over Opvoeden. 2009 13-02-09. Lecture: Personality disorders. Neurobiology of Early Trauma (AMC, Faculty of Medicine). 16-02-09. 2-hour guestlecture on How to settle conflicts, Law Faculty, UvA. 26-03-09. Neurobiology: the neurobiology of aggression: a prelude to violence? Lecture at the UvA. Violence in peace and war: interdisciplinary perspectives. 05-06-09. Programmering van het brein. Lecture Students of Medicine, AMC, UvA 13-07-09. Neurodegeneration and the dementias. AMC Summer School on Exploring the Brain, AMC/NIN Amsterdam. 17-07-09. The Netherlands Brain Bank. AMC Summer School on Exploring the Brain, AMC/NIN, Amsterdam. 02-10-09. Hypothalamic Disorders. Course on Medical Neuroscience & Neuroanatomy, VU University Amsterdam. 17-11-09. Presentation to the new ONWAR students. 24-11-09. Collegereeks 'Wetenschappers over Opvoeden'. Pedagogische Wetenschappen, UvA, Carine Ex, Roetersstraat, Amsterdam. 48

2010 20-01-10 Fellowsprogramma: 3-hour Lecture on Development of Character/De Ontwikkeling van ons Karakter. 19-03-10 Blok 3.4. Lecture Early Traumatization (Faculty of Medicine, AMC/UvA), Psychiatric Disorders. 25-06-10 Hogeschool van Amsterdam, Module: Origin of diseases in the womb/ontstaan van ziekten in de baarmoeder. Programmering van het brein. 08-10-10 Gastcollege Neuropsychologie VU, Amsterdam Guest lectures at the Zhejang University Medical School, Hangzhou, PR China. 03-12-10 Neurobiology, clinics and society. - Programming of the brain: sexual differentia - Functional teratology: chemicals and pregnancy - Dementias: reactivation of neurons in Alzheimer s disease - New therapies and the old problem of placebos. 04-12-10 - Demonstration Human Brain Dissection (4 hrs) 07-12-10 - Programming of the brain: sexual differentia - Functional teratology: chemicals and pregnancy - Dementias: reactivation of neurons in Alzheimer s disease - New therapies and the old problem of placebos. 2011 22-02-11 Interdisciplinary Keuzecollege, Het Brein: Wat weten wetenschappers en wat kunnen we daarmee. - Brein en Ontwikkeling (2-hour lecture). 07-03-11 - Seksuele ontwikkeling van de hersenen. Endocrinology course, highlight lecture, Science Park, Amsterdam 14-03-11 AMC Blok 3.4 Psychiatrische stoornissen - Neurobiologie van vroege traumatisering. 06-06-11 Biomedical Sciences, LUMC Leiden - Hersenen en homoseksualiteit - Stelling, n.a.v. Wij zijn ons Brein. 24-06-11 Keuze-onderwijs Huisartsengeneeskunde (E. Fokke, VUmc), 2 hour lecture We are our brains 16-09-11 Psychologie college VU: Hypothalamic disorders 21-10-11 Medical Neuroscience & Neuroanatomy 2011/2012, AMC: Hypothalamic disorders 01-11-11 Sexual Differentiation. In Mastercourse Endocrinology, The Endocrinology of Stress, Hogeschool van Amsterdam, Amsterdam. 04-11-11 Anatomy and Function of the human hypothalamus. Lecture within the framework of Experimental and Clinical Neuroscience, VUmc Amsterdam, meeting room De Linge. - Lecture for Beijing HuiLongGuan Hospital, PR China Lectures as Chao Kuang Piu Professor of Zhejian University, Hangzhou, P.R.China 14-11-11 Neuroscience and its impact on society. - Development of the brain: programming of sexual differentiation, language and religion - Programming of the brain, criminal behavior and law - Dementias and reactivation of neurons - New therapies from neurosciences and the old problem of placebo 16-11-11 Neuroscience and its impact on society. - Development of the brain: programming of sexual differentiation, language and religion - Programming of the brain, criminal behavior and law - Dementias and reactivation of neurons - New therapies from neurosciences and the old problem of placebo 17-11-11 Masterclass research group Prof. Dr. A.M. Bao 18-11-11 Half-day discussion with the faculty of Philosophy, Zhejiang University; Neuroscience and Philosphy 21-11-11 Depression and the necessity of brain banking. Hangzhou Psychiatric Hospital. 49

23-11-11 Forum key lecture Does our brain decide everything? Faculty of Social Sciences, Zhejiang University, Hangzhou, PR China 2012 06-03-2012 Seksuele differentiatie van onze hersenen. 2-Hour Lecture at SILS, UvA. 12-03-2012 Vroege traumatisering. 1-hour lecture at AMC, Faculty of Medicine (section Child Psychiatry) 12-03-2012 Hersenontwikkeling en de vorming van ons karakter. 2-hour lecture (evening) Science Park Amsterdam, within the framework of the lecture cycle: the Brain. Lectures held at Hangzhou University, China, in capacity of Professor of this university. 11-05-2012 Speech and Language 12-05-2012 Brain and Mind Lectures held at Hefei University, China, in capacity of Professor of this university 14-05-2012 We are our brain 16-05-2012 Brain Pathology (5-hour lecture) 17-05-2012 The Brain decides who you are 50

PUBLICATIONS of Dick Frans SWAAB 51

MONOGRAPHS 2003 1. Swaab DF. The Human Hypothalamus. Basic and Clinical Aspects. Part I: Nuclei of the Hypothalamus, Handbook of Clinical Neurology, Elsevier, Amsterdam. Series Editors: M.J. Aminoff, F. Boller, D.F. Swaab, vol. 79, 476 pp. 2004 1. Swaab DF. The Human Hypothalamus. Basic and Clinical Aspects. Part II: Neuropathology of the Hypothalamus and Adjacent Brain Structures. Handbook of Clinical Neurology, Elsevier, Amsterdam. Series Editors: M.J. Aminoff, F. Boller, D.F. Swaab, vol. 80, 596 pp. These books were reviewed by Fliers E, for J. Neuroendocrinology 16: 1009-1010, 2004 Lucassen PJ, for J. Neuropathol. Exp. Neurol. 64: 260-261, 2005 Lucassen PJ. for Neurology 64: 1668-1669, 2005 Hoogendijk WJG. for Tijdschrift voor Psychiatrie 46: 856-857, 2005 2010 1. Swaab, DF. Wij zijn ons brein. Van baarmoeder tot Alzheimer. Uitgeverij Contact, Amsterdam, pp. 400. This book was reviewed in Elsevier, Trouw, Volkskrant, Arts and Auto, NRC Handelsblad and many other publications. Please see the section Book Reviews of Wij zijn ons Brein at the end of this CV. 52

ARTICLES IN JOURNALS (*special attention) 1967 1 Jongkind JF, DF Swaab - The distribution of thiamine diphosphate-phosphohydrolase in the neurosecretory nuclei of the rat following osmotic stress. Histochemie 11, 319-324, 1967. 1970 2 Swaab DF - Factors influencing neurosecretory activity of the supraoptic and paraventricular nuclei in rat, a histochemical and cytochemical study. Med. Diss., Amsterdam, 1970. 3 Swaab DF, JF Jongkind - The hypothalamic neurosecretory activity during the oestrus cycle, pregnancy, parturition, lactation and persistent oestrus, and after gonadectomy, in the rat. Neuroendocrinology 6, 133-145, 1970. 1971 4 Swaab DF - Pitfalls in the use of rapid freezing for stopping brain and spinal cord metabolism in rat and mouse. J. Neurochem. 18, 2085-2092, 1971. 5 Swaab DF, JF Jongkind - Influence of gonadotropic hormones on the hypothalamic neurosecretory activity in the rat.neuroendocrinology 8, 36-47, 1971. 6 Swaab DF, JF Jongkind, AA De Rijke-Arkenbout - Quantitative histochemical study on the influence of lactation and changing levels of gonadotropic hormones on rat supraoptic nucleus. Endocrinology 89, 1123-1126, 1971. 1972 7 Swaab DF, K Boer - The presence of biologically labile compounds during ischemia and their relationship to the EEG in the rat cerebral cortex and hypothalamus. J. Neurochem. 19, 2843-2853, 1972. 8 Swaab DF, LG Fransman - Reacties van patiënten op de aanwezigheid van een semi-arts in een huisarts praktijk. Huisarts en Wetenschap 15, 346-350, 1972. 1973 9 Honnebier WJ, DF Swaab - The influence of anencephaly upon intrauterine growth of fetus and placenta and upon gestation length. J. Obstet. Gynaec. Brit. Cwlth. 80, 577-588, 1973. 10 Swaab DF, WJ Honnebier - The influence of removal of the fetal brain upon intrauterine growth of the fetus and the placenta and on gestation length. J. Obstet. Gynaec. Brit. Clwth. 80, 589-597, 1973. 1974 11 Honnebier WJ, DF Swaab - Influence of alpha-melanocyte-stimulating hormone (alpha-msh), growth hormone (GH) and fetal brain extracts on intrauterine growth of fetus and placenta in the rat. J. Obstet. Gynaec. Brit. Clwth. 81, 439-447, 1974. 12 Honnebier WJ, AC Jöbsis, DF Swaab - The effect of hypophysial hormones and human chorionic gonadotropin (HCG) on the anencephalic fetal adrenal cortex and on parturition in the human. J. Obstet. Gynaec. Brit. Clwth. 81, 423-438, 1974. 13 Lincoln DW, K Boer, DF Swaab - Measurements of intramammary pressure in rats by a pressure sensitive radio-pill. Physiol. Behav. 12, 289-292, 1974. 1975 14 Boer K, DW Lincoln, DF Swaab - Effects of electrical stimulation of the neurohypophysis on labour in the rat. J. Endocr. 65, 163-176, 1975. 15 Swaab DF, CW Pool - Specificity of oxytocin and vasopressin- immuno- fluorescence. J. Endocr. 66, 263-272, 1975. 16 Swaab DF, F Nijvelt, CW Pool - Distribution of oxytocin and vasopressin in the rat supraoptic and paraventricular nucleus. J. Endocr. 67, 461-462, 1975. *17 Swaab DF, CW Pool, F Nijvelt - Immunofluorescence of vasopressin and oxytocin in the rat hypothalamo-neurohypophyseal system. J. Neural Transm. 36, 195-215, 1975. This paper is a 'citation classic' of Current Contents, vol. 33 (no. 30) 1990. 1976 18 Boer GJ, FW Van Leeuwen, DF Swaab, JWL Nolten - Acid phosphatase activity in the rat neurohypophysis during increased levels of gonadotropic hormones, in diabetes insipidus (Brattleboro 53

strain) and after water loading. Acta Endocr. 81, 697-706, 1976. 19 Swaab DF, M Visser, FJH Tilders - Stimulation of intrauterine growth in rat by alpha-melanocytestimulating hormone. J. Endocr. 70, 445-455, 1976. 1977 20 Dogterom J, TjB Van Wimersma Greidanus, DF Swaab - Evidence for the release of vasopressin and oxytocin into cerebrospinal fluid: measurements in plasma and CSF of intact and hypophysectomized rats. Neuroendocrinology 24, 108-118, 1977. 21 Swaab DF, CW Pool, FW Van Leeuwen - Can specificity ever be proved in immunocytochemical staining? Letter to the Editor, J. Histochem. Cytochem. 25, 388-391, 1977. 22 Swaab DF, FW Van Leeuwen, J Dogterom, WJ Honnebier - The fetal hypothalamus and pituitary during growth and differentiation. J. Steroid Biochem. 8, 545-551, 1977. 23 Van Leeuwen FW, DF Swaab - Specific immunoelectronmicroscopic localization of vasopressin and oxytocin in the neurohypophysis of the rat. Cell Tiss. Res. 177, 493-501, 1977. 1978 24 Buijs RM, DF Swaab, J Dogterom, FW Van Leeuwen - Intra- and extrahypothalamic vasopressin and oxytocin pathways in the rat. Cell Tiss. Res. 186, 423-433, 1978. 25 Swaab DF, B Fisser - Immunocytochemical localization of alpha- melanocyte stimulating hormone (alpha-msh)-like compounds in the rat nervous system. Neurosci. Lett. 7, 313-317, 1978. 26 Van Leeuwen FW, DF Swaab, C De Raay - Immunoelectron microscopic localization of vasopressin in the rat suprachiasmatic nucleus. Cell Tiss. Res. 193, 1-10, 1978. 1979 27 Boer K, DF Swaab, M Visser - The fetal brain and parturition. Animal Reprod. Sci. 2, 63-75, 1979. 28 Boer HH, LPC Schot, EW Roubos, A Ter Maat, JC Lodder, D Reichelt, DF Swaab - ACTH-like immunoreactivity in two electrotonically coupled giant neurons in the pond snail Lymnea Stagnalis. Cell Tiss. Res. 202, 231-240, 1979. 29 Buijs RM, DF Swaab - Immuno-electron microscopical demonstration of vasopressin and oxytocin synapses in the limbic system of the rat. Cell Tiss. Res. 204, 355-365, 1979. 30 Pévet P, DF Swaab - Immunocytochemical evidence for the presence of an alpha-msh-like compound in the rat pineal gland. J. Physiol., Paris, 75, 101-103, 1979. 31 Tilders FJH, HA Van der Woude, DF Swaab, AH Mulder - Identification of MSH release -inhibiting elements in the neurointermediate lobe of the rat. Brain Res. 171, 425-435, 1979. 32 Van Leeuwen FW, C De Raay, DF Swaab, B Fisser - The localization of oxytocin, vasopressin, somatostatin and luteinizing hormone in the rat neurohypophysis. Cell Tiss. Res. 202, 189-201, 1979. 33 Visser M, DF Swaab - Life span changes in the presence of melanocyte stimulating hormone containing cells in the human pituitary. J. Developm. Physiol. 1, 161-178, 1979. 1980 34 Boer GJ, RM Buijs, DF Swaab, GJ De Vries - Vasopressin and the developing rat brain. Peptides 1: Suppl.1, 203-209, 1980. 35 Buijs RM, DN Velis, DF Swaab - Ontogeny of vasopressin and oxytocin in the fetal rat: early vasopressinergic innervation of the fetal brain. Peptides 1, 315-324, 1980. 36 Dogterom J, FGM Snijdewint, P Pévet, DF Swaab - Studies on the presence of vasopressin, oxytocin and vasotocin in the pineal gland, subcom- missural organ and fetal pituitary gland: failure to demonstrate vasotocin in mammals. J. Endocr. 84, 115-123, 1980. 37 Pévet P, I Ebels, DF Swaab, MT Mud, A Arimura - Presence of AVT- -MSH-, LHRH- and somatostatinlike compounds in the rat pineal gland and their relationship with the UMO5R pineal fraction: an immunocytochemical study. Cell Tiss. Res. 206, 341-353, 1980. 38 Swaab DF - Bederven wij de hersenen van onze kinderen reeds voor hun geboorte? Publikatie inaugurale rede, 28 april 1980, Faculteit der Geneeskunde van de Universiteit van Amsterdam, 1980. 1981 39 Boer K, GJ Boer, DF Swaab - Reproduction in Brattleboro rats with diabetes insipidus. J. Reprod. Fert. 61, 273-280, 1981. 40 De Vries GJ, RM Buijs, DF Swaab - Ontogeny of the vasopressinergic neurons of the suprachiasmatic nucleus and their extrahypothalamic projections in the rat brain - presence of a sex difference in the lateral septum. Brain Res. 218, 67-78, 1981. 54

41 Schot LPC, HH Boer, DF Swaab, S Van Noorden - Immunocytochemical demonstration of peptidergic neurons in the central nervous system of the pond snail Lymnaea stagnalis with antisera raised to biologically active peptides of vertebrates. Cell Tiss. Res. 216, 273-291, 1981. 42 Swaab DF - Bederven wij de hersenen van onze kinderen reeds voor hun geboorte? T. Verloskundigen 6(7/8), 189-198, 1981 (see inaug. lecture). 43 Swaab DF - Bederven wij de hersenen van onze kinderen reeds voor hun geboorte? T. Ziekenverpl. 34(23), 1014-1021, 1981 (see inaug. lecture). 44 Fliers E, DF Swaab - Activation of vasopressinergic and oxytocinergic neurons during aging in the Wistar rat. Peptides 4: 165-170, 1983. 45 Goodfellow CF, MGR Hull, DF Swaab, J Dogterom, RM Buijs - Oxytocin deficiency at delivery with epidural analgesia. Brit. J. Obstet. Gynaecol. 90, 214-219, 1983. 46 Swaab DF, GJ Boer - Neuropeptides and brain development. Current perils and future potential. J. Devel. Physiol. 5, 67-75, 1983. 47 Swaab DF, HP Oosterbaan - Exclusion of the fetal brain as the main source of rat and human amniotic fluid oxytocin. Br. J. Obstet. Gynaecol. 90, 1160-1167, 1983. 1984 48 Boer GJ, R Kragten, J Kruisbrink, DF Swaab - Vasopressin fails to restore postnatally the stunted brain development in the Brattleboro rat, but affects water metabolism permanently. Neurobehav. Toxicol. Teratol., 6, 103-110, 1984. 49 Swaab DF, MA Hofman - Sexuele differentiatie van de menselijke hersenen. Wending 39 (no.2), 75-81, 1984. 1985 50 Boer GJ, Swaab DF - Neuropeptide effects on brain development to be expected from behavioral teratology. Peptides 6, suppl.2, 21-28, 1985. 51 De Vries GJ, RM Buijs, FW Van Leeuwen, AR Caffé, DF Swaab - The vasopressinergic innervation of the brain in normal and castrated rats. J. Comp. Neurol. 233, 236-254, 1985. 52 Fliers E, GJ De Vries, DF Swaab - Changes with aging in the vasopressin and oxytocin innervation of the rat brain. Brain Res. 48, 1-8, 1985. 53 Fliers E, DF Swaab, CW Pool, RWH Verwer - The vasopressin and oxytocin neurons in the human supraoptic and paraventricular nucleus; changes with aging and in senile dementia. Brain Res. 342, 45-53, 1985. 54 Hoogendijk JE, E Fliers, DF Swaab, RWH Verwer - Activation of vasopressin neurons in the human supraoptic and paraventricular nucleus in senescence and senile dementia. J. Neurol. Sci. 69, 291-299, 1985. 55 Mirmiran M, E Brenner, J Van der Gugten, DF Swaab - Neurochemical and electrophysiological disturbances mediate developmental behavioral alterations produced by medicines. Neurobeh. Toxicology and Teratology 7, 677-683, 1985. 56 Oosterbaan HP, DF Swaab, GJ Boer - Increased amniotic vasopressin levels in experimentally growthretarded rat fetuses. J. Devel. Physiol. 7, 89-97, 1985. 57 Oosterbaan HP, DF Swaab, GJ Boer - Oxytocin and vasopressin in the rat do not readily pass from the mother to the amniotic fluid in late pregnancy. J. Devel. Physiol. 7, 55-62, 1985. 58 Ravid R, DF Swaab, CW Pool - Light microscopic immunocytochemical localization of vasopressin binding sites in the rat kidney. J. Endocrinol., 105, 133-140, 1985. 59 Snijdewint FGM, GJ Boer, DF Swaab - Body and brain growth following continuous perinatal administration of arginine- and lysine-vasopressin to the homozygous Brattleboro rat. Devel. Brain Res.22, 269-277, 1985. *60 Swaab DF, E Fliers - A sexually dimorphic nucleus in the human brain. Science 228, 1112-1115, 1985. 61 Swaab DF, E Fliers and B. Fisser - The vasopressin-containing neuron in the human brain; changes during aging and senile dementia. Brit.J. Clinical Practise 39, 7-10, 1985. 62 Swaab DF, E Fliers, T Partiman - The suprachiasmatic nucleus of the human brain in relation to sex, age and dementia, Brain Res. 342, 37-44, 1985. 1986 63 Fliers E, SEF Guldenaar, N van de Wal, DF Swaab - Extrahypothalamic vasopressin and oxytocin in the human brain; presence of vasopressin cells in the bed nucleus of the stria terminalis. Brain Res. 375, 363-367, 1986. 64 Mirmiran M, DF Swaab - Central neurotransmitter disturbances underlying developmental 55

neurotoxicological effects. J. Neurotoxicology 7, 95-102, 1986. 65 Ravid R, HP Oosterbaan, BL Hansen, DF Swaab - Localisation of oxytocin, vasopressin and parts of precursors in the human neonatal adrenal. Histochemistry 84, 401-407, 1986. 66 Ravid R, DF Swaab, E Fliers, JE Hoogendijk - Verhoogde vasopressine productie gedurende ouderdom en dementie. Tijdschrift v. Gerontologie en Geriatrie 17, 136-140, 1986. 67 Ravid R, DF Swaab, TP van der Woude, GJ Boer - Immunocytochemically stained vasopressin binding sites in rat brain. Ventricular application of vasopressin Accurel in the Brattleboro rat. J. Neurol. Sci.76, 317-333, 1986. 68 Ravid R, DF Swaab, TP van de Woude, GJ Boer - Immunocytochemically stained binding sites for oxytocin and a-melanocyte stimulating hormone in rat brain following ventricular administration. Brain Res. 379, 404-408, 1986. 69 Swaab DF - De hersenontwikkeling van het kind bij de verslaafde moeder. TGO (Tijdschrift voor Therapie, Geneesmiddel en Onderzoek) 11, 254-257, 1986. 70 Swaab DF - Fundamenteel onderzoek van hersenen en het gebruik ervan door medici. Vakblad voor Biologen 66, 335-337, 1986. 71 Swaab DF, MA Hofman, E Fliers - Sexuele differentiatie van de menselijke hersenen. Ned. T. Geneeskunde, Caput Selectum 130, 106-110, 1986. 72 Van der Sluis PJ, GJ Boer, DF Swaab - Vasopressin and oxytocin in the developing rat brain as shown by isoelectric focusing of radioimmunoassayable peptides. Dev. Brain Research 26, 85-90, 1986. 1987 73 Fliers E, DF Swaab - Neurobiologisch onderzoek naar veroudering en de ziekte van Alzheimer; achtergronden van de organisatie van een hersenbank. Vox Hospitii, 11(3), 73-76, 1987. 74 Mirmiran M, DF Swaab - Influence of drugs on brain neurotransmitters and behavioral states during development. Dev. Pharmacol. Ther.10, 377-384, 1987. 75 Oosterbaan HP, DF Swaab - Circulating neurohypophysial hormones in anencephalic infants. Am. J. Obstet. and Gynec. 157, 117-119, 1987. 76 Ravid R, E Fliers, DF Swaab, C Zurcher - Changes in vasopressin and plasma testosterone in the senescent Brown-Norway BN/BiRij rat. Gerontology 33, 87-98, 1987. 77 Roozendaal B, WA van Gool, DF Swaab, JE Hoogendijk, M Mirmiran - Changes in vasopressin cells of the rat suprachiasmatic nucleus with aging. Brain Res.409, 259-264, 1987. 78 Swaab DF - De klok in onze hersenen. 11th Holst lecture, Techn. Univ. Eindhoven, 1987. 79 Swaab DF and E. Fliers - Vasopressin systems in the rat and human brain; their changes in relation to aging and dementia. Reinhardsbrunn Symp. 1986, Math.- Naturwiss. R. 36, 165-169, 1987. 80 Swaab DF and HBM Uylings - Comments on review by Coleman and Flood `Neuron numbers and dendritic extend in normal aging and Alzheimer's disease', Density measures: parameters to avoid. Neurobiol. of Aging 8, 574-575, 1987. 1988 81 Chee CA, B Roozendaal, DF Swaab, E Goudsmit, M Mirmiran - Vasoactive intestinal polypeptide and vasopressin changes in the senile rat suprachiasmatic nucleus. Neurobiology of Aging, 9, 307-312, 1988. 82 Goudsmit E, E Fliers, DF Swaab - Vasopressin and oxytocin excretion in the Brown-Norway rat in relation to aging, water metabolism and testosterone. Mech. Ageing and Development 44, 241-252, 1988. 83 Goudsmit E, E Fliers, DF Swaab - Testosterone supplementation restores vasopressin innervation in the senescent rat brain. Brain Res. 473, 306-313, 1988. 84 Hofman MA, E Fliers, E Goudsmit, DF Swaab - Morphometric analysis of the suprachiasmatic and paraventricular nuclei in the human brain: sex differences and age-dependent changes. J. Anat. 160, 127-143, 1988. 85 Mirmiran M, J Overdijk, W Witting, A Klop, DF Swaab - A simple method for recording and analysing circadian rhythms in man. J. Neurosci. Meth. 25, 209-214, 1988. 86 Oosterbaan HP, DF Swaab - Oxytocine en vasopressine in het amnionvocht bij de mens en de rat. Tijdschr. v. Diergeneesk. 113, 677-680, 1988. 87 Oosterbaan HP, DF Swaab, MA Hofman - Het op gang komen van de baring: een kwestie van energie? Medisch Journaal Groot Ziekengasthuis 's-hertogenbosch, 3, 205-216, 1988 88 Oosterbaan HP, DF Swaab - Oxytocine en vasopressine in het amnionvocht bij de mens en de rat. Tijdschr. Diergeneeskunde, 113, 677-680, 1988. 89 Ravid R, DF Swaab - De Hersenbank. Tijdschr. v. Ziekenverpl. 42, 358-360, 1988. 56

90 Snijdewint FGM, GJ Boer, DF Swaab - Prenatal development of the Brattleboro rat is influenced by genotype and lysine vasopressin treatment of the mother. Biol. Neonate 53, 295-304, 1988. 91 Swaab DF - Wij zijn onze hersenen. EOS Magazine 11, p. 139, 1988. 92 Swaab DF, MA Hofman - Sexual differentiation of the human hypothalamus: ontogeny of the sexually dimorphic nucleus of the preoptic area. Devel. Brain Res. 44, 314-318, 1988. 93 Swaab DF, B Fisser, W Kamphorst, D Troost - The human suprachiasmatic nucleus; neuropeptide changes in senium and Alzheimer's disease. Basic Appl. Histochem.32, 434, 1988. 94 Swaab DF, E Goudsmit, E Fliers - Veroudering en de ziekte van Alzheimer: de ontwikkeling van een nieuwe onderzoekslijn binnen het Nederlands Instituut voor Hersenonderzoek. Verband 12 (3), 5-6, 1988. 95 Turkenburg JL, DF Swaab, E Endert, AL Louwerse, NE van de Poll - Effects of lesions of the sexually dimorphic nucleus on sexual behavior of testosterone-treated female Wistar rats. Brain Res. Bull. 21, 215-224, 1988. 96 Van Zwieten EJ, R Ravid, DF Swaab, Tj vd Woude - Immunocytochemically stained vasopressin binding sites on blood vessels in the rat brain. Brain Res. 474, 369-373, 1988. 1989 97 Hofman MA, DF Swaab - The sexually dimorphic nucleus of the preoptic area in the human brain: a comparative, morphometric study. J. Anat. 164, 55-72, 1989. 98 Mirmiran M, DF Swaab, W Witting, MBOM Honnebier, WA Van Gool, P Eikelenboom - Biological clocks in development, aging and Alzheimer's disease. Brain Dysfunct. 2, 57-66, 1989. 99 Oosterbaan HP, DF Swaab - Amniotic oxytocin and vasopressin in relation to human fetal development and labor. Early Human Development 19, 253-262, 1989. 100 Swaab DF. - Blijvende effecten van chemische stoffen op het zich ontwikkelende zenuwstelsel: functionele teratologie. Ned. Tijdschr. v. Geneesk. 133, 246-249, 1989. 101 Swaab DF - De fitrace naar de dood. Elseviers Magazine 45 (nr.5, 4-2-1989), p. 107. 102 Swaab DF, JJ Hauw, GP Reynolds, S Sorbi - Tissue Banking and EURAGE, J. Neurol. Sci. 93: 341-343, 1989. 103 Troost D, JJ Van den Oord, JMBV De Jong, DF Swaab - Lymphocytic infiltration in the spinal cord of patients with amyotrophic lateral sclerosis. Clin. Neuropathol. 8, 289-294, 1989. 1990 104 Duyckaerts C, P Delaere, JJ Hauw, AL Abbamondi-Pinto, S Sorbi, I Allen, JP Brion, J Flament-Durand, L Duchen, J Kauss, W Schlote, J Lowe, A Probst, R Ravid, DF Swaab, K Renkawek, B Tomlinson - Rating of the lesions in senile dementia of the Alzheimer type: concordance between laboratories: a European multicentric study under the auspices of EURAGE. J. Neurol. Sci. 97, 295-323, 1990. 105 Ghanbari H., BE Miller, HJ Haigler, M Arato, G Bissette, P Davies, Ch Nemeroff, E Perry, R Perry, R Ravid, DF Swaab, WO Whetsell, FP Zemlan - Biochemical Assay of Alzheimer's Disease: Associated Protein(s) in Human Brain Tissue. JAMA 263, 2907-2910, 1990. 106 Goudsmit E, MGP Feenstra, DF Swaab - Central monoamine metabolism in the male Brown-Norway rat in relation to aging and testosterone. Brain Res. Bull., 25, 755-763, 1990. 107 Goudsmit E, MA Hofman, E Fliers, DF Swaab - The supraoptic and paraventricular nuclei of the human hypothalamus in relation to sex, age and Alzheimer's disease. Neurobiology of Aging, 11, 529-536, 1990. 108 Goudsmit E, VN Luine, DF Swaab - Testosterone locally increases vasopressin content but fails to restore choline acetyltransferase activity in the senescent male rat brain. Neurosci. Lett. 112, 290-296, 1990. 109 Goudsmit E, NE Van de Poll, DF Swaab - Testosterone fails to reverse spatial memory decline in aged rats and impairs retention in young and middle-aged animals. Behav. Neural Biol. 53, 6-20, 1990. 110 Hofman MA, E Goudsmit, JS Purba, DF Swaab - Morphometric analysis of the supraoptic nucleus in the human brain. J. Anat. 172, 259-270, 1990. 111 Mullaert E, MET Boerrigter, R Ravid, DF Swaab, J Vijg - Increased levels of DNA breaks in cerebral cortex of Alzheimer's disease patients. Neurobiology of Aging 11, 169-173, 1990. 112 Skene DJ, B Vivien-Roels, DL Sparks, P Pevet, R Ravid, DF Swaab - Daily variation in the concentration of melatonin and 5-methoxytryptophol in the human pineal gland: effect of age and Alzheimer's disease. Brain Res., 528, 170-174, 1990. 113 Swaab DF - Immunofluorescence of vasopressin and oxytocin, Citation Classic Current Contents 22, no. 28, 9 July, p.34 (Social and Behavioral Sciences) and no. 30, 23 July (Life Sciences), 1990. *114 Swaab DF, MA Hofman - An enlarged suprachiasmatic nucleus in homosexual men. Brain Res. 537, 141-148, 1990. 115 Swaab DF, MA Hofman, MBOM Honnebier - Development of vasopressin neurons in the human 57

suprachiasmatic nucleus in relation to birth. Dev. Brain. Res. 52, 289-293, 1990. 116 Van Eerdenburg FJCM, P Poot, GJ Molenaar, FW van Leeuwen, DF Swaab - A vasopressin and oxytocin containing nucleus in the pig hypothalamus that shows neuronal changes during puberty, J. Comp. Neurol. 301, 138-146, 1990. 117 Witting W, IH Kwa, P Eikelenboom, M Mirmiran, DF Swaab - Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease. Biol. Psychiatr. 27, 563-572, 1990. 1991 118 Hofman MA, DF Swaab - Sexual dimorphism of the human brain: myth and reality, Exp. Clin. Endocrinol. 98, 161-170, 1991. 119 Kremer HPH, DF Swaab, GThAM Bots, B Fisser, R Ravid, RAC Roos -The hypothalamic lateral tuberal nucleus in Alzheimer's disease, Ann. Neurol. 29, 279-284, 1991. *120 Swaab DF - Brain aging and Alzheimer's disease: "wear and tear" versus "use it or lose it". Neurobiol. Aging, 12, 317-324, 1991. 121 Swaab DF - Author's response to Commentaries, Neurobiology of Aging 12, 352-355, 1991. 122 Swaab DF - Het syndroom van Prader-Willi en de hypothalamus. In: Contactblad Prader-Willi Vereniging no. 2, 3-5, december 1991. Tevens in Belgisch Kontactblad jaargang 4, nummer 2/3, p. 7-9. 123 Van Eerdenburg FJCM, CMJE Lugard-Kok, SJ Dieleman, MM Bevers, DF Swaab - Influence of gonadectomy and testosterone supplementation on the postnatal development of the vasopressin and oxytocin containing nucleus of the pig hypothalamus. Neuroendocrinology, 54: 580-586, 1991. 124 Van Eerdenburg FJCM, DF Swaab - Increasing neuron numbers in the vasopressin and oxytocin containing nucleus of the adult female pig hypothalamus, Neuroscience Letters, 132: 85-88, 1991. 125 Van Zwieten EJ, R Ravid, PJ Van der Sluis, AA Sluiter, CW Pool, D Smyth, DF Swaab - Increased vasopressin immunoreactivity in the rat brain after a postmortem interval of 6 hours. Brain Res. 550, 263-267, 1991. 126 Wierda M, E Goudsmit, PF Van der Woude, JS Purba, MA Hofman, H Bogte, DF Swaab - Oxytocin cell number in the human paraventricular nucleus remains constant with aging and in Alzheimer's disease, Neurobiol. Aging 12: 511-516, 1991. 1992 127 Bahnsen U, P Oosting, DF Swaab, P Nahke, D Richter, H Schmale - A missense mutation in the vasopressin-neurophysin precursor gene cosegregates with human autosomal dominant neurohypophyseal diabetes insipidus, The EMBO journal, vol. 11, no. 1, 19-23, 1992. 128 Hofman MA, DF Swaab - Seasonal changes in the suprachiasmatic nucleus of man, Neuroscience Letters, 139, 257-260, 1992. 129 Romijn HJ, AWJW Janszen, MJD Van Voorst, RM Buijs, R Balázs, DF Swaab - Perinatal hypoxic ischemic encephalopathy affects the proportion of GABA-immunoreactive neurons in the cerebral cortex of the rat. Brain Research 592: 17-28, 1992. 130 Romijn HJ, AWJW Janszen, MJD Van Voorst, RM Buijs, R Balázs, DF Swaab - Perinatal hypoxia and epilepsy. Acta Antwerpgentia 9, 24-36. 131 Swaab DF - How to prevent the retiring brain from degenerating, Clinical Neurology and Neurosurgery, 94, S150-S152, 1992. 132 Swaab DF, I Grundke-Iqbal, K Iqbal, HPH Kremer, R Ravid, JAP van de Nes - Tau and ubiquitin in the human hypothalamus in aging and Alzheimer's disease. Brain Res. 590: 239-249 (1992). 133 Swaab DF - The Prader-Willi syndrome and the hypothalamus. Pickwick Papers (Newsletter of the Prader-Willi Syndrome Association) May 1992. Also in The Open Door (Prader-Willi Syndrome Association Australia, no. 2, p. 9-11, 1992). 134 Swaab DF, LJG Gooren, MA Hofman - Gender and Sexual Orientation in relation to hypothalamic structures. Hormone Res. 38 (suppl.): 51-61, 1992. 135 Troost D, PAE Sillevis Smitt, JMBV De Jong, DF Swaab - Neurofilament and glia alterations in the cerebral cortex in amyotrophic lateral sclerosis, Acta Neuropathol. 84: 664-673, 1992 136 Van Eerdenburg FJCM, CMJE Lugard-Kok, DF Swaab - The supraoptic nucleus in the pig hypothalamus: postnatal development and the effect of gonadal steroids. J. Endocrinology 134, 19-25, 1992. 137 Van Eerdenburg FJCM, DF Swaab, FW Van Leeuwen - Distribution of vasopressin and oxytocin cells and fibres in the hypothalamus of the domestic pig (Sus scrofa), J. Comp. Neurol., 318: 138-146, 1992. 1993 138 Hofman MA, JS Purba, DF Swaab - Annual variations in the vasopressin neuron population of the 58

human suprachiasmatic nucleus. Neuroscience 53: 1103-1112, 1993. 139 Hofman MA, DF Swaab - Diurnal and seasonal rhythms of neuronal activity in the suprachiasmatic nucleus of humans. J. Biol. Rhythms 8: 283-295. 140 Kruijver FPM, FH De Jonge, WT Van den Broek, T Van der Woude, E Endert, DF Swaab - Lesions of the suprachiasmatic nucleus do not disturb sexual orientation of the adult male rat. Brain Res. 624: 342-346, 1993 141 Lucassen PJ, R Ravid, NK Gonatas, DF Swaab - Activation of the human supraoptic and paraventricular nucleus neurons with aging and in Alzheimer's disease as judged from increasing size of the Golgi apparatus. Brain Research 632: 105-113 (1993). 142 Panayotacopoulou MT, DF Swaab - Development of tyrosine hydroxylase-immunoreactive neurons in the human paraventricular and supraoptic nucleus. Dev. Brain Res. 72: 145-150, 1993. 143 Purba JS, MA Hofman, D Troost, DF Swaab - Decreased number of oxytocin neurons in the paraventricular nucleus of human hypothalamus in AIDS. Brain 116: 795-809. 144 Raadsheer FC, AA Sluiter, R Ravid, FJH Tilders, DF Swaab - Localization of corticotropin-releasing hormone (CRH) neurons in the paraventricular nucleus of the human hypothalamus; age-dependent colocalization with vasopressin. Brain Res. 615: 50-62, 1993. 145 Ravid R, DF Swaab - The Netherlands Brain Bank - a clinico-pathological link in aging and dementia research. J. Neural Transm. [Suppl.] 39: 143-153, 1993. 146 Swaab DF - Neurohypophyseal peptides in the human hypothalamus in relation to development, sexual differentiation, aging and disease. Regulatory Peptides 45: 143-147, 1993. 147 Swaab DF, MA Hofman, JAP Van de Nes, JS Purba, FC Raadsheer, PJ Lucassen - Functional neuroanatomy and neuropathology of the human hypothalamus. Anat. & Embryol. 187: 317-330, 1993. 148 Taphoorn MJB, EJW Van Someren, FJ Snoek, RLM Strijers, DF Swaab, F Visscher, LP De Waal, CH Polman - Fatigue, sleep disturbances and circadian rhythm in multiple sclerosis. J. Neurol. 240: 446-448 (1993) 149 Troost D, N Claessen, JJ Van den Oord, DF Swaab, JMBV De Jong - Neuronophagia in the motor cortex in amyotrophic lateral sclerosis. Neuropathology and Applied Neurobiology 19, 390-397, 1993. 150 Van de Nes JAP, W Kamphorst, R Ravid, DF Swaab - The distribution of Alz-50 immunoreactivity in the hypothalamus and adjoining areas of Alzheimer's disease patients. Brain, 116: 103-115, 1993. 151 Van der Post JAM, A Konijnenberg, K Boer, MCL Schaap, CEA Van Boxtel, A Sturk, GJ Boer, DF Swaab - Preeclampsia is not associated with altered platelet vasopressin binding and cytosolic Ca2+ concentration. Am. J. Obstetr. & Gynecol., 169, 1169-1178, 1993. 152 Van Someren EJW, WA Van Gool, BFM Vonk, M Mirmiran, JD Speelman, DA Bosch, DF Swaab - A new method for the ambulatory registration of tremor and movement. J. Neurol. Sci. 117: 16-23, 1993. 153 Van Someren EJW, Mirmiran M, Swaab DF - Non-pharmacological treatment of sleep and wake disturbances in aging and Alzheimer's disease: chronobiological perspectives. Behav. Brain Res. 57: 235-253, 1993. 154 Van Zwieten EJ, WT Kos, R Ravid, DF Swaab - Decreased number of vasopressin immunoreactive neurons in the medial amygdala and locus coeruleus of the aged rat, Neurobiology of Aging 14: 245-248, 1993. 155 Van Zwieten EJ, DF Swaab - Neurohypophysial peptides in the human brain in relation to development, sexual differentiation, aging and disease. Neuroendocrinology Lett. 15: 1-11, 1993. 156 Witting W, Mirmiran M, Bos NPA, Swaab DF - Effect of Light Intensity on Diurnal Sleep-Wake Distribution in Young and Old Rats. Brain Research Bulletin 30: pp. 157-162, 1993. 1994 157 Fliers E, Noppen NWAM, Wiersinga WM, Visser TJ, Swaab DF - Distribution of thyrotropin-releasing hormone(trh)-containing cells and fibers in the human hypothalamus. J. Comp. Neurol. 350: 311-323, 1994 158 Gabreëls BAThF, DF Swaab, NG Seidah, JLP Van Duijnhoven, GJM Martens, FW Van Leeuwen - Differential expression of the neuroendocrine polypeptide 7B2 in hypothalami of Prader-(Labhart)-Willi syndrome patients. Brain Research 657: 281-293, 1994. 159 Hofman MA, Swaab DF - Alterations in circadian neuronal rhythmicity of the human suprachiasmatic nucleus (SCN) with aging. Brain Research 651: 134-142, 1994. 160 Kudo T, K Iqbal, R Ravid, DF Swaab, I Grundke-Iqbal - A competitive enzyme-linked immunoflow assay for ubiquitin in cerebrospinal fluid. Neuroreport 5: 1522-1524, 1994. 161 Kudo T, K Iqbal, R Ravid, DF Swaab, I Grundke-Iqbal - Alzheimer disease: correlation of cerebrospinal fluid and brain ubiquitin levels. Brain Research 639, 1-7, 1994. 162 Lucassen PJ, A Salehi, CW Pool, NK Gonatas, DF Swaab - Activation of vasopressin neurons in aging 59

and Alzheimer's disease. J. Neuroendocr. 6: 673-680, 1994. 163 Panayotacopoulou MT, Raadsheer FC, Swaab DF - Colocalization of tyrosine hydroxylase with oxytocin or vasopressin in neurons of the human paraventricular and supraoptic nucleus. Dev. Brain Research 83: 59-66, 1994. 164 Purba JS, Hofman MA, Swaab DF - Decreased number of oxytocin-immunoreactive neurons in the paraventricular nucleus of the hypothalamus in Parkinson's disease. Neurology 44, 84-89 (1994). 165 Raadsheer FC, DE Oorschot, RWH Verwer, FJH Tilders, DF Swaab - Age-related increase in the total number of corticotropin-releasing hormone neurons in the human paraventricular nucleus in controls and Alzheimer's disease: comparison of the disector with an unfolding method. J. Comp. Neurol. 339: 447-457. 166 Raadsheer FC, FJH Tilders, DF Swaab - Similar age related increase of vasopressin colocalization in paraventricular corticoptropin-releasing hormone neurons in controls and Alzheimer patients. J. Neuroendocrinol. 6, 131-133 (1994). 167 Raadsheer FC, Hoogendijk WJG, Stam FC, Tilders FJH, Swaab DF. - Increased numbers of corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus of depressed patients. Neuroendocrinology 60: 436-444, 1994. 168 Salehi A, PJ Lucassen, CW Pool, NK Gonatas, R Ravid, DF Swaab - Decreased neuronal activity in the nucleus basalis of Meynert in Alzheimer's disease as suggested by the size of the Golgi apparatus. Neuroscience 59: 871-880, 1994. 169 Swaab DF, MA Hofman, PJ Lucassen, A Salehi, HBM Uylings - Neuronal atrophy, not cell death, is the main hallmark of Alzheimer's disease. Neurobiology of Aging 15: 369-371, 1994. 170 Swaab DF, JN Zhou, T Ehlhart, MA Hofman - Development of vasoactive intestinal polypeptide (VIP) neurons in the human suprachiasmatic nucleus (SCN) in relation to birth and sex. Dev. Brain Research 79: 249-259, 1994. 171 Swaab DF, FC Raadsheer, E Endert, MA Hofman, W Kamphorst, R Ravid. Increased cortisol levels in aging and Alzheimer's disease in postmortem cerebrospinal fluid. J. Neuroendocrinology 6: 681-688, 1994. 172 Van de Nes JAP, Sluiter AA, Pool CW, Kamphorst W, Ravid R, Swaab DF - The monoclonal antibody Alz-50, used to reveal cytoskeletal changes in Alzheimer's disease, also reacts with somatostatinergic neurons in the normal human hypothalamus and adjoining areas. Brain Research 655: 97-109, 1994. 173 Van de Nes JAP, Kamphorst W, Swaab DF - Arguments for and against the primary amyloid local induction hypothesis on the pathogenesis of Alzheimer's disease. Ann. Psychiatry 4: 95-111, 1994. 174 Van der Post JA, Van Heerikhuize JJ, Boer K, Van Boxtel CE, Swaab DF - Radioimmunoassay of vasopressin during pregnancy. Use and removal of cystylaminopeptidase inhibitors. Clinica Chimica Acta 230: 125-136, 1994. 175 Van Eerdenburg FJCM, DF Swaab - Postnatal development and sexual differentiation of pig hypothalamic nuclei. Psychoneuroendocrinology 19 (5-7): 471-484, 1994. 176 Van Zwieten EJ, R Ravid, WJG Hoogendijk, DF Swaab - Stable vasopressin innervation in the degenerating human locus coeruleus in Alzheimer's disease. Brain Research 649: 329-333, 1994. 177 Witting W, M Mirmiran, NPA Bos, DF Swaab - The effect of old age on the free-running period of circadian rhythms in rat. Chronobiology International 11: 103-112, 1994. 1995 178 De Vos RAI, ENH Jansen, FC Stam, R Ravid, H Begthel, H Ploegmakers, DF Swaab - "Lewy body disease": clinico-neuro-pathological correlations in 18 consecutive cases of Parkinson's disease. Clinical Neurology and Neurosurgery 97: 13-22, 1995. 179 Erkut ZA, MA Hofman, R Ravid, DF Swaab - Increased activity of hypothalamic corticotropin-releasing hormone (CRH) neurons in multiple sclerosis. J. Neuroimmunol. 62: 27-33, 1995. 180 Guldenaar SEF, Swaab DF - Estimation of oxytocin mrna in the human paraventricular nucleus in AIDS by means of quantitative in situ hybridization. Brain Research 700: 107-114. 181 Hofman MA, Skene DJ, Swaab DF - Effect of photoperiod on the diurnal melatonin and 5- methoxytryptophol rhythms in the human pineal gland. Brain Res. 671: 254-260. 182 Hofman MA, Swaab DF - Influence of aging on the seasonal rhythm of the human suprachiasmatic nucleus (SCN). Neurobiology of Aging 16: 965-971. 183 Hoogendijk WJG, Pool CW, Troost D, Van Zwieten EJ, Swaab DF - Image-analyzer-assisted morphometry of the locus coeruleus in Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. Brain, 118, 131-143. * Material from this paper was selected by the journal to serve as cover illustration. 184 Lucassen PJ, E Goudsmit, G Mengod, JM Palacios, FC Raadsheer, SEF Guldenaar, DF Swaab - In situ 60

hybridization for vasopressin mrna in the human supraoptic and paraventricular nucleus; quantitative aspects of formalin-fixed paraffin-embedded tissue sections as compared to cryostat sections. J. Neuroscience Methods 57: 221-230, 1995 (& corrigendum in J. Neurosci. Meth. 64 (1996) 133). 185 Lucassen PJ, Chung WCJ, Vermeulen JP, Van Lookeren Campagne M, Van Dierendonck JH, Swaab DF - Microwave-enhanced in situ end-labeling of fragmented DNA; parametric studies in relation to post mortem delay and fixation of rat and human brain, J. Histochem. Cytochem. 43: 1163-1171, 1995. 186 Lucassen PJ, Hofman MA, Swaab DF - Increased light intensity prevents the age related loss of vasopressin-expressing neurons in the rat suprachiasmatic nucleus. Brain Res. 693: 261-266, 1995. 187 Portela A, Cornélissen G, Halberg F, Halberg J, Hofman MA, Swaab DF, Ikonomov OC, Stoynev AG - Metachronalysis of circannual and circasemiannual characteristics of human suprachiasmatic vasopressin-containing neurons. In Vivo 9: 347-358, 1995. 188 Purba JS, Raadsheer FC, Hofman MA, Ravid R, Polman CH, Kamphorst W, Swaab DF - Increased number of corticotropin releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus of patients with multiple sclerosis. Neuroendocrinology 62: 62-70, 1995. *189 Raadsheer FC, Van Heerikhuize JJ, Lucassen PJ, Hoogendijk WJG, Tilders FJH, DF Swaab - Increased corticotropin-releasing hormone (CRH) mrna in the paraventricular nucleus of patients with Alzheimer's disease or depression. Am. J. Psychiatry 152, 1372-1376, 1995. 190 Salehi A, Van de Nes JAP, Hofman MA, Gonatas NK, Swaab DF - Early cytoskeletal changes as shown by Alz-50 are not accompanied by decreased neuronal activity. Brain Res., 678: 29-39. 191 Salehi A, Ravid R, Gonatas NK, Swaab DF - Decreased activity of hippocampal neurons in Alzheimer's disease is not related to the presence of neurofibrillary tangles. J. Neuropathol. Exptl. Neurol. 54, 704-709 (1995). 192 Salehi A, Heyn S, Gonatas NK, Swaab DF - Decreased protein synthetic activity of the hypothalamic tuberomammillary nucleus in Alzheimer's disease as suggested by a smaller Golgi apparatus. Neurosci. Lett. 193: 29-32, 1995. 193 Scherder EJA, Bouma A, Steen L, Swaab DF - Peripheral nerve stimulation in Alzheimer's disease; A meta-analysis. Alzheimer's Research 1: 183-184 (1995). 194 Swaab DF - Ageing of the human hypothalamus. Horm. Res. 43: 8-11, 1995. 195 Swaab DF, Hofman MA - Sexual differentiation of the human hypothalamus in relation to gender and sexual orientation. (Trends in Neurosciences (TINS) 18: 264-270. *Material from this paper was selected by the journal to serve as cover illustration. 196 Swaab DF, LJG Gooren, MA Hofman - Brain Research, Gender and Sexual Orientation. J. Homosexuality 28: 283-301, 1995. 197 Swaab DF, Slob AK, Houtsmuller EJ, Brand T, Zhou JN - Increased number of vasopressin neurons in the suprachiasmatic nucleus (SCN) of "bisexual" adult male rats following perinatal treatment with the aromatase blocker ATD. Dev. Brain Res., 85: 273-279. 198 Swaab DF, Purba JS, Hofman MA - Alterations in the hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) in Prader-Willi syndrome: A study of five cases. J. Clin. Endocrin. Metab. 80(2):573-579. 199 Swaab DF - Development of the human hypothalamus. Neurochem. Res. 20(5), 509-519, 1995 200 Swaab DF - Kan activatie van het zenuwstelsel het Alzheimerproces gunstig beïnvloeden? COBObulletin 2: 3-6, 1995. 201 Van der Woude PF, Goudsmit E, Wierda M, Purba JS, Hofman MA, Bogte H, Swaab DF - No vasopressin cell loss in the human paraventricular and supraoptic nucleus during aging and in Alzheimer's disease. Neurobiology of Aging, 16: 11-18. 202 Van Leeuwen FW, Chouham S, Axelson JF, Swaab DF, Van Eerdenburg FJCM - Sex differences in the distribution of estrogen receptors in the septal area and hypothalamus of the domestic pig (sus scrofa). Neuroscience 64(1): 261-275. 203 Witting W, Boerma D, Koster-van Hoffen GC, Swaab DF, Mirmiran M. - Light suppresses frequency and endogenous amplitude of the circadian system in nocturnal animals. Biological Rhythm Research 26: 477-485, 1995. 204 Zhou JN, Hofman MA, Swaab DF - VIP neurons in the human SCN in relation to sex, age and Alzheimer's disease. Neurobiol. Aging 16, 571-576. *205 Zhou JN, Hofman MA, Gooren LJG, Swaab DF - A sex difference in the human brain and its relation to transsexuality. Nature 378: 68-70, 1995. Reprinted with permission in the Int. J. Transgenderism 1 in 1997 (electronic journal). 206 Zhou JN, Hofman MA, Swaab DF - No changes in the number of vasoactive intestinal polypeptide (VIP) expressing neurons in the suprachiasmatic nucleus of homosexual men; comparison with vasopressin expressing neurons. Brain Res. 672: 285-288. 61

1996 207 Evans DAP, JPH Burbach, DF Swaab, FW Van Leeuwen - Mutant vasopressin precursors in the human hypothalamus: evidence for neuronal somatic mutations in man. Neuroscience 71: 1025-1030. 208 Guldenaar SEF, B Veldkamp, O Bakker, WM Wiersinga, DF Swaab, E Fliers - Thyrotropin-releasing hormone gene expression in the human hypothalamus. Brain Res. 743: 93-101. *Material from this paper was selected by the journal to serve as cover illustration. 209 Hofman MA, Zhou JN, Swaab DF - Suprachiasmatic nucleus of the human brain: an immunocytochemical and morphometric analysis. The Anatomical Record 244: 552-562, 1996. 210 Hofman MA, Zhou JN, Swaab DF - No evidence for a diurnal vasoactive intestinal polypeptide (VIP) rhythm in the human suprachiasmatic nucleus. Brain Research 722: 78-82, 1996. 211 Hoogendijk WJG, Van Someren EJW, Mirmiran M, Hofman MA, Lucassen PJ, Zhou JN, Swaab DF - Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer s disease. Int. Psychogeriatrics 8, suppl. 3: 245-252 and 269-272, 1996. 212 Korting C, EJ Van Zwieten, GJ Boer, R Ravid, DF Swaab - Increase in vasopressin binding sites in the human choroid plexus in Alzheimer's disease. Brain Res. 706: 151-154, 1996. 213 Mirmiran M, Van Someren EJW, Swaab DF - Is brain plasticity preserved during aging and in Alzheimer's disease. Behavioural Brain Research 78: 43-48, 1996 214 Purba JS, Hoogendijk WJG, Hofman MA, Swaab DF - Increased number of vasopressin and oxytocin expressing neurons in the paraventricular nucleus of the human hypothalamus in depression. Arch. Gen. Psych. 53: 137-143, 1996. *215 Salehi A, Verhaagen J, Dijkhuizen PA, Swaab DF - Colocalization of high affinity neurotrophin receptors in nucleus basalis of Meynert neurons and their differential reduction in Alzheimer's disease. Neuroscience 75: 373-378, 1996. 216 Te Koppele JM, Lucassen PJ, Sakkee AN, Van Asten JG, Ravid R, Swaab DF, Van Bezooijen CFA - 8- OHdG levels in brain do not indicate oxidative DNA damage in Alzheimer s disease. Neurobiol. Aging 17: 819-826. 217 Timmers HJLM, Swaab DF, Van de Nes JAP, Kremer HPH - Somatostatin 1-12 immunoreactivity is decreased in the hypothalamic lateral tuberal nucleus of Huntington's disease patients. Brain Res. 728: 141-148, 1996. 218 Van Someren EJW, Hagebeuk EEO, Lijzenga C, Scheltens P, De Rooij SEJA, Jonker C, Pot AM, Mirmiran M, Swaab DF - Circadian rest-activity rhythm disturbances in Alzheimer's disease. Biol. Psych. 40: 259-270, 1996. 219 Van Someren EJW, Lazeron RHC, Vonk BFM, Mirmiran M, Swaab DF - Gravitational artefact in frequency spectra of movement acceleration: implications for actigraphy in young and elderly subjects. J. Neurosci. Meth. 65: 55-62, 1996. 220 Van Zwieten EJ, Ravid R, Swaab DF - Differential vasopressin and oxytocin innervation of the human parabrachial nucleus: no changes in Alzheimer's disease. Brain Res. 711: 146-152, 1996. 221 Zhou JN, Hofman MA, Swaab DF - Morphometric analysis of vasopressin and vasoactive intestinal polypeptide neurons in the human suprachiasmatic nucleus: influence of microwave treatment. Brain Res. 742: 334-338, 1996. 1997 222 Dai J, Swaab DF, Buijs RM - Distribution of vasopressin and vasoactive intestinal polypeptide (VIP) fibers in the human hypothalamus with special emphasis on suprachiasmatic nucleus efferent projections. J. Comp. Neurol. 383: 397-414, 1997. 223 Fliers E, Guldenaar SEF, Wiersinga WM, Swaab DF - Decreased hypothalamic thyrotropin-releasing hormone (TRH) gene expression in patients with nonthyroidal illness. J. Clin. Endocr. Metab. 82: 4032-4036, 1997. 224 Lucassen PJ, Chung WCJ, Kamphorst W, Swaab DF - DNA damage distribution in the human brain as shown by in situ end labeling: area specific differences in aging and Alzheimer's disease. J. Neuropathol. Exp. Neurol. 56: 887-900. 225 Lucassen PJ, Van Heerikhuize JJ, Guldenaar SEF, Pool CW, Hofman MA, Swaab DF - Unchanged amounts of vasopressin mrna in the supraoptic and paraventricular nucleus during aging and in Alzheimer's disease. J. Neuroendocrinology 9: 297-305, 1997. 226 Swaab DF, Salehi A - Letter to the Editor. J. Neuropathol. Exp. Neurol. 56: 216, 1997. 227 Van der Post JAM, Van Buul BJA, Hart AAM, Van Heerikhuize JJ, Pesman G, Legros JJ, Steegers EAP, Swaab DF, Boer K. - Vasopressin and oxytocin levels during normal pregnancy: effects of chronic dietary sodium restriction. J. Endocrinol. 152: 345-354, 1997. 62

228 Van Someren EJW, Lijzenga C, Mirmiran M, Swaab DF - Long-term fitness training improves the circadian rest-activity rhythm in healthy elderly males. J. Biol. Rhythms 12: 146-156, 1997. 229 Van Someren EJW, Kessler A, Mirmiran M, Swaab DF - Indirect bright light improves circadian restactivity rhythm disturbances in demented patients. Biol. Psychiatr. 41: 955-963, 1997. 1998 230 Dai JP, Van der Vliet J, Swaab DF, Buijs RM - The human retinohypothalamic tract as revealed by in vitro postmortem tracing. J. Comp. Neurol. 397: 357-370, 1998. *231 Dai JP, Swaab DF, Buijs RM - Recovery of axonal transport in dead neurons. Lancet 351: 499-500. 232 Dai JP, Swaab DF, Van der Vliet J, Buijs RM - Postmortem tracing reveals the organization of hypothalamic projections of the suprachiasmatic nucleus in the human brain. J. Comp. Neurol. 400: 87-102. 233 Dai JP, Van der Vliet J, Swaab DF, Buijs RM - Postmortem anterograde tracing of intrahypothalamic projections of the human dorsomedial nucleus of the hypothalamus. J. Comp. Neurol. 401: 16-33. 234 Erkut Z, Pool CW, Swaab DF - Glucocorticoids suppress corticotropin-releasing hormone (CRH) and vasopressin (AVP) expression in human hypothalamic neurons. J. Clin. Endocr. Metab. 83: 2066-2973, 1998 235 Gabreëls BAThF, Swaab DF, De Kleijn DPV, Dean A, Seidah NG, Van de Loo J-W, Van de Ven WJM, Martens GJM, Van Leeuwen FW - The vasopressin precursor is not processed in the hypothalamus of Wolfram syndrome patients with diabetes insipidus: evidence for the involvement of PC2 and 7B2. J. Clin. Endocr. Metabol. 83: 4026-4033, 1998. 236 Gabreëls BAThF, Swaab DF, De Kleijn DPV, Seidah NG, Van de Loo J-W, Van de Ven WJM, Martens GJM, Van Leeuwen FW - Attenuation of the polypeptide 7B2, prohormone convertase PC2 and vasopressin in the hypothalamus of some Prader-Willi patients: indications for a processing defect. J. Clin. Endocr. Metab. 83: 591-599. 237 Hoogendijk WJG, Purba JS, Hofman MA, De Vos RAI, Jansen ENH, Swaab DF - Depression in Parkinson s disease is not accompanied by more corticotropin-releasing hormone expressing neurons in the hypothalamic paraventricular nucleus. Biol. Psych. 43: 913-917, 1998. 238 Lucassen PJ, Van Someren EJW, Swaab DF - Zijn actieve neuronen beter bestand tegen veroudering en de ziekte van Alzheimer? Tijdschrift voor Gerontologie en Geriatrie 29: 177-183, 1998. *239 Mayer A, Swaab DF, Pilgrim C, Reisert I, Lahr G - Genes involved in male sex determination are expressed in adult human brain. Neurogenetics 1: 281-288, 1998 240 Mulder M, Ravid R, Swaab DF, De Kloet ER, Haasdijk E, Kulk J, Van der Boom J, Havekes LM - Reduced levels of cholesterol, phospholipids and fatty acids in cerebrospinal fluid of Alzheimer s disease patients are not related to apolipoprotein E4. Alzheimer s Dis. Assoc. Disorders 12: 198-203, 1998. 241 Oleana V, Salehi A, Swaab DF - Increased expression of the TIAR protein in the hippocampus of Alzheimer patients. Neuroreport 9: 1451-1454, 1998. 242 Salehi A, Bakker JM, Mulder M, Swaab DF - Limited effect of senile plaques on neuronal density in the hippocampal CA1 Area of Alzheimer patients. Alzh. Dis. Assoc. Disorders. 12: 77-82, 1998. *243 Salehi A, Dubelaar EJG, Mulder M, Swaab DF - Decreased activity of nucleus basalis neurons in Alzheimer s disease is ApoE type dependent. PNAS 95: 11445-11449. 244 Salehi A, Pool CW, Mulder M, Ravid R, Gonatas NK, Swaab DF - Activity of hippocampal CA1 neurons in Alzheimer s disease is not affected by the presence of adjacent neuritic plaques. J. Alzh. Disease 1: 107-118. 245 Salehi A, Gonzalez-Martinez V, Swaab DF - A sex difference and no effect of ApoE-type on the amount of cytoskeletal alterations in the nucleus basalis of Meynert in Alzheimer s disease. Neurobiol. Aging 19: 505-510, 1998 246 Scherder EJA, Bouma A, Van Someren EJW, Swaab DF - Beneficial effects of peripheral nerve stimulation on cognition, behaviour and the rest-activity rhythm in Alzheimer s disease. Neurosci. News 1: 18-25. 247 Van de Nes JAP, Kamphorst W, Ravid R, Swaab DF - ComParison of beta-protein/a4 deposits and Alz- 50-stained cytoskeletal changes in the hypothalamus and adjoining areas of Alzheimer's disease patients: amorphic plaques and cytoskeletal changes occur independently. Acta Neuropathol. 96: 129-138, 1998. 248 Van Someren EJW, Scherder EJA, Swaab DF - Transcutaneous electrical nerve stimulation (TENS) improves circadian rhythm disturbances in Alzheimer's disease. Alzheimer s Disease and Associated Disorders 12: 114-118, 1998. 249 Van Someren EJ, Vonk BFM, Thijssen W, Speelman JD, Schuurman PR, Mirmiran M, Swaab DF - A 63

new actigraph for long-term registration of the duration and intensity of tremor and movement. IEEE 45: 386-395, 1998. 1999 *250 Hoogendijk WJG, Sommer IEC, Pool CW, Kamphorst W, Hofman MA, Eikelenboom P, Swaab DF - Lack of association between depression and the loss of neurons in the locus coeruleus in Alzheimer s disease. Arch. Gen. Psychiatry 56: 45-51. *251 Hoogendijk WJG, Feenstra MPG, Botterblom MHA, Gilhuis J, Sommer IEC, Kamphorst W, Eikelenboom P, Swaab DF - Increased activity of surviving locus coeruleus neurons in Alzheimer s disease. Annals of Neurology, 45: 82-91. 252 Hoogendijk WJG, Swaab DF - Klinische consequenties van centrale activatie van de hypothalamushypofyse-bijnier as. Tijdschrift Psychiatrie 41: 597-601. 253 Huitinga I, Van der Cammen MMJF, Fisser B, Swaab DF - Detectie van cytokines in paraffine-ingebed formaline-gefixeerd hersenweefsel van multiple sclerose patiënten. Histotechniek en Cytovisie 5: 19-22. 254 Ishunina TA, Swaab DF - Vasopressin and oxytocin neurons of the human supraoptic and paraventricular nucleus: size changes in relation to sex and age. J. Clin. Endocrinol. Metabol. 84: 4637-4644. 255 Ishunina TA, Salehi A, Hofman MA, Swaab DF - Activity of vasopressinergic neurons of the human supraoptic nucleus is age and sex dependent. J. Neuroendocr. 11: 251-258. 256 Liu R, Zhou JN, Van Heerikhuize JJ, Hofman MA, Swaab DF - Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer s disease and ApoE- 4/4 genotype. J. Clin. Endocrinol. Metabol. 84: 323-327. 257 Salehi A, Swaab DF - Diminished neuronal metabolic activity in Alzheimer s disease. J. Neural Transm. 106: 995-986. 258 Salehi A, Ocampo M, Verhaagen J, Swaab DF - P75 neurotrophin receptor in the nucleus basalis of Meynert in relation to age, sex and Alzheimer s disease. Exp. Neurol. 161: 245-258. 259 Scherder EJA, Van Someren EJW, Swaab DF - Epilepsy: a possible contraindication for transcutaneous electrical nerve stimulation. Letter to the Editor. J. Pain Sympt. Management 17: 152-153. 260 Swaab DF - Hypothalamic peptides in human brain diseases. Trends Endocrinol. Metabol. 10: 236-244. 261 Van Someren EJW, Swaab DF, Colenda CC, Cohen W, Vaughn McCall W, Rosenquist PB - Bright light therapy: improved sensitivity to its effects on rest-activity rhythms in Alzheimer patients by application of non-parametric methods. Chronobiol. Int. 16: 505-518, 1999. 262 Van Someren EJW, Scherder EJA, Lijzenga C, Swaab DF - Het slaap-waakritme bij veroudering en dementie. Modern Medicine7:628-633. 263 Zhou JN, Swaab DF - Activation and degeneration during aging: a morphometric study of the human hypothalamus. Microscopy Res. and Techn. 44: 36-48. 2000 264 Chung WCJ, Swaab DF, De Vries GJ - Apoptosis during sexual differentiation of the bed nucleus of the stria terminalis in the rat brain. J. Neurobiol. 43: 234-243. 265 Fernandez-Guasti A, Fodor M,Kruijver FPM, Swaab DF - Sex differences in the distribution of androgen receptors in the human hypothalamus. J. Comp. Neurol. 425: 422-435. 266 Hoogendijk WJG, Meynen G, Eikelenboom P, Swaab DF - Brain alterations in depression. Acta Neuropsychiatrica 12: 54-58. 267 Huitinga I, Van der Cammen MJF, Salm LP, Erkut ZA, Van Dam AM, Tilders FJH, Swaab DF - Interleukin-1 immunoreactive neurons in the human hypothalamus: changes in the paraventricular nucleus in multiple sclerosis. J. Neuroimmunology 107: 8-20, 2000. 268 Ishunina, T.A., Salehi, A. and Swaab, D.F. - Sex- and age-related P75 neurotrophin receptor expression in the human supraoptic nucleus. Neuroendocrinology 71: 243-251. 269 Ishunina, T.A., Unmehopa, U.A., Dolzhikov, A.A., Swaab, D.F. - Multinucleated arginine-vasopressin neurons in the human supraoptic nucleus: A hallmark of pulmonary pathology. Neuroendocrinology 72: 318-326. 270 Ishunina, T.A., Kruijver, F.P.M., Balesar, R., Swaab, D.F. - Differential expression of estrogen receptor and immunoreactivity in the human supraoptic nucleus in relation to sex and aging. J. Clin. Endocr. Metabol. 85: 3283-3291. 271 Kruijver, F.P.M., Zhou, J.N., Pool, C.W., Hofman, M.A., Gooren, L.J.G., Swaab, D.F. - Male-to-female transsexuals have female neuron numbers in a limbic nucleus. J. Clin. Endocrinol. Metabol. 85: 2034-2041, 2000. This paper was awarded the GIRES (Gender Identity Research and Education 64

Society) prize 2002. *272 Liu, R.Y., Zhou, J.N., Hoogendijk, W.J.G., van Heerikhuize, J., Kamphorst, W., Unmehopa, U.A., Hofman, M.A. and Swaab, D.F. - Decreased vasopressin gene expression in the biological clock of Alzheimer s disease patients with and without depression. J. Neuropath. Exptl. Neurol. 59: 314-322, 2000. 273 Panayotacopoulou, M.T., Goudsmit, E., Van Heerikhuize, J.J., Swaab, D.F. - Simultaneous detection of tyrosine hydroxylase-immunoreactivity and vasopressin mrna in neurons of the human paraventricular and supraoptic nucleus. Brain Res. 855: 181-185. 274 Scherder, E.J.A., Van Someren, E.J.W. and Swaab, D.F. - Transcutaneous electrical nerve stimulation (TENS) improves the rest-activity rhythm in midstage Alzheimer s disease. Behav. Brain Res. 101: 105-107. 275 Van Leeuwen, F.W., Kamel, D., Sluijs, J.A., Sonnemans, M.A.F., Fischer, D.F., Benne, R., Swaab, D.F., Salehi, A., Hol, E.M. - Molecular misreading: a new type of transcript mutation expressed during aging. Neurobiol. Aging 21: 879-891. 276 Verwer, R.W.H., Jansen, K.A., Sluiter, A.A., Pool, C.W., Kamphorst, W., Swaab, D.F. - Decreased hippocampal metabolic activity in Alzheimer patients is not reflected in the immunoreactivity of cytochrome oxidase subunits. Exp. Neurol. 163: 440-451. 2001 277 Fliers, E., Unmehopa, U., Manniesing, S., Wiersinga, W.M., Swaab, D.F. - Decreased neuropeptide Y (NPY) expression in the infundibular nucleus of patients with nonthyroidal illness. Peptides 22: 459-465. 278 Goncharuk, V.D., Van Heerikhuize, J.J., Dai, J.P., Swaab, D.F., Buijs, R.M. - Neuropeptide changes in the suprachiasmatic nucleus in primary hypertension indicate functional impairment of the biological clock. J. Comp. Neurol. 431: 320-330. 279 Hoogendijk, W.J.G., Meynen, G., Feenstra, M.G., Eikelenboom, P., Kamphorst, W., Swaab, D.F. - Verhoogde activiteit van stressregulerende systemen bij de ziekte van Alzheimer. Gerontol. Geriatr. 32: 17-23. 280 Huitinga, I., Van Beurden, D., De Groot, C.J.A., Van der Valk, P., Kamphorst, W., Tilders, F.J.H., Swaab, D.F. - Hypothalamic lesions in multiple sclerosis. J. Neuropath. Exptl. Neurol. 60: 1208-1218. 281 Ishunina, T.A. and Swaab, D.F. - Increased expression of estrogen receptor and in the nucleus basalis of Meynert in Alzheimer s disease. Neurobiol. Aging 22: 417-426. 282 Ishunina, T.A.,Unmehopa, U.A., Van Heerikhuize, J.J., Pool, C.W., Swaab, D.F. - Metabolic activity of the human ventromedial nucleus neurons in relation to sex and aging. Brain Res. 893: 70-76. 283 Kruijver, F.P.M., Fernandez-Guasti, A., Fodor, M., Kraan, E.M., Swaab, D.F. - Sex differences in androgen receptors of the human mamillary bodies are related to endocrine status rather than to sexual orientation or transsexuality. J. Clin. Endocrinol. Metabol. 86: 818-827. *284 Lucassen, P.J., Müller, M.B., Holsboer, F., Bauer, J., Holtrop, A., Wouda, J., Hoogendijk, W.J.G., De Kloet, E.R., Swaab, D.F. - Hippocampal apoptosis in major depression is a rare event and absent from subareas at risk for glucocorticoid overexposure. Am. J. Pathol. 158: 453-468. 285 Müller, M.B., Lucassen, P.J., Yassouridis, A., Hoogendijk, W.J.G., Holsboer, F., Swaab, D.F. - Neither major depression nor glucocorticoid treatment affects the cellular integrity of the human hippocampus. Eur. J. Neurosci.14: 1603-1612. 286 Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A., Ishunina, T.A. - Structural and functional sex differences in the human hypothalamus. Horm. Behav. 40: 93-98. *287 Zhou, J.N., Riemersma, R.F., Unmehopa, U.A., Hoogendijk, W.J.G., Van Heerikhuize, J.J., Hofman, M.A. and Swaab, D.F. - Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression. Arch. Gen. Psychiatry 58: 655-662. 2002 *288 Chung, W.C.J., De Vries, G.J., Swaab, D.F. - Sexual differentiation of the bed nucleus of the stria terminalis in humans may extend into adulthood. J. Neurosci. 22: 1027-1033. 289 Dai, J., Buijs, R.M., Kamphorst, W., Swaab, D.F. (2002) Impaired axonal transport of cortical neurons in Alzheimer s disease is associated with neuropathological changes. Brain Res. 948: 138-144. 290 Erkut, Z.A., Endert, E., Huitinga, I., Swaab, D.F. - Cortisol is increased in postmortem cerebrospinal fluid of multiple sclerosis patients: relationship with cytokines and sepsis. Multiple Sclerosis 8: 229-236. 291 Erkut, Z.A., Gabreëls, B.A.Th.F., Eikelenboom, J., Van Leeuwen, F.W., Swaab, D.F. - Glucocorticoid treatment is associated with decreased expression of processed AVP but not of proavp, neurophysin or oxytocin in the human hypothalamus: Are PC1 and PC2 involved? Neuroendocrinol. Lett. 23: 33-44. 292 Fodor, M., Van Leeuwen, F.W., Swaab, D.F. - Differences in post mortem stability of sex steroid receptor immunoreactivity in rat brain. J. Histochemistry & Cytochemistry 50: 641-649. 65

293 Goldstone, A.P., Unmehopa, U.A., Swaab, D.F. - Hypothalamic NPY and AGRP are increased in human illness but not in Prader-Willi syndrome and other obese subjects. J. Clin. Endocrinol. Metab. 87: 927-937. 294 Goncharuk, V.D., Van Heerikhuize, J.J., Swaab, D.F., Buijs, R.M. - Paraventricular nucleus of the human hypothalamus in primary hypertension: activation of corticotropin-releasing hormone neurons. J. Comp. Neurol. 443: 321-331. 295 Hu, X-Y., Zhang, H.Y., Qin, S., Xu, H., Swaab, D.F., Zhou, J-N. - Increased p75 NTR expression in hippocampal neurons containing hyperphosphorylated tau in Alzheimer patients. Exptl. Neurol. 178: 104-111. 296 Ishunina, T.A., Swaab, D.F. - Sex differences in androgen receptor immunoreactivity in the cholinergic nuclei of the basal forebrain of elderly and Alzheimer patients. Exptl. Neurol. 176: 122-132. 297 Ishunina, T.A., Swaab, D.F. - Neurohypophyseal peptides in aging and Alzheimer s disease. Ageing Res. Revs. 31: 1-22. 298 Ishunina, T.A., Wouda, J., Fisser, B., Swaab, D.F. - Sex differences in estrogen receptor and expression in vasopressin neurons of the supraoptic nucleus in elderly and Alzheimer s disease patients: no relationship with cytoskeletal alterations. Brain Res. 951: 322-329. 299 Kruijver, F.P.M., Balesar, R., Espila, A.M., Unmehopa, U.A., Swaab, D.F. - Estrogen receptor- distribution in the human hypothalamus in relation to sex and endocrine status. J. Comp. Neurol. 454: 115-139. 300 Kruijver, F.P.M., Swaab, D.F. - Sex hormone receptors are present in the human suprachiasmatic nucleus. Neuroendocrinology 75: 296-305. *301 Overeem, S., Van Vliet, J.A., Lammers, G.J., Zitman, F.G., Swaab, D.F., Ferrari, M.D. (2002) The hypothalamus in episodic brain disorders. Lancet Neurol. 1: 437-444 302 Panayotacopoulou, M.T., Malidelis, Y., Fliers, E., Bouras, C., Ravid, R., Swaab, D.F. - Increased expression of tyrosine hydroxylase immunoreactivity in neurons of the paraventricular and supraoptic nucleus in illnesses with prolonged osmotic or non-osmotic stimulation of vasopressin release. Neuroendocrinology 76: 254-266. 303 Pandi-Perumal, S.R., Seils, L.K., Kayumov, L., Ralph, M.R., Lowe, A., Moller, H., Swaab, D.F. - Senescence, sleep, and circadian rhythms. Ageing Res. Rev. 1: 559-604. 304 Scherder, E.J.A., Deijen, J.B., Vreeswijk, S.H., Sergeant, J.A., Swaab, D.F. - Cranial electrostimulation (CES) in patients with probable Alzheimer s disease. Behav. Brain Res. 128: 215-217. 305 Swaab, D.F. - The complex effects of sex hormones on the brain: it all depends on species, sex, age and cell type. XX vs. XY 1: 1-2. 306 Swaab, D.F., Chung, W.C., Kruijver, F.P.M., Hofman, M.A., Ishunina, T.A. - Sexual differentiation of the human hypothalamus. Adv. Exp. Med. Biol. 511: 75-100 (Discussion 100-5). 307 Trottier, S., Chotard, C., Traiffort, E., Unmehopa, U., Fisser, B., Swaab, D.F., Schwartz, J.C. - Colocalization of histamine with GABA but not with galanin in the human tuberomamillary nucleus. Brain Res. 939: 52-64. 308 Van Someren, E.J.W., Raymann, R.J.E.M., Scherder, E.J.A., Daanen, H.A.M., Swaab, D.F. - Circadian and age-related modulation of thermoreception and temperature regulation: mechanisms and functional implications. Ageing Res. Rev. 1: 721-778. *309 Verwer, R.W.H., Hermens, W.T.J.M.C., Dijkhuizen, P.A., Ter Brake, O., Baker, R.E., Salehi, A., Sluiter, A.A., Kok, M.J.M., Müller, L.J., Verhaagen, J., Swaab, D.F. - Cells in human post-mortem brain tissue slices remain alive for several weeks in culture. FASEB J. 16: 54-60. 310 Verwer, R.W.H., Hermens, W.T.J.M.C., Ter Brake, O., Verhaagen, J., Swaab, D.F. - Life after death? Neurology 59: p. 2006. 311 Verwer, R.W.H., Dubelaar, E.J.G., Hermens, W.T.J.M.C., Swaab, D.F. - Tissue cultures from adult human postmortem subcortical brain areas. J. Cell. Mol. Med. 6: 429-432. 2003 312 Alkemade, A., Unmehopa, U.A., Brouwer, J.P., Hoogendijk, W.J.G., Wiersinga, W.M., Swaab, D.F., Fliers, E. - Decreased thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus (PVN) of patients with major depression. Molec. Psychiatr. 8: 838-839 313 De Rijk, R., Schaaf, M., Stam, F.J., De Jong, I.E.M., Swaab, D.F., Vreugdenhof, E., Cidlowski, J.A., De Kloet, E.R., Lucassen. P.J. - Very low levels of the glucocorticoid receptor beta isoform in the human hippocampus as shown by Taqman RT-PCR and immunocytochemistry. Mol. Brain Res. 116: 17-26. 314 Fernandez-Guasti, A., Rodriguez-Manzo, G., Swaab, D.F. - Sexual behaviour reduces hypothalamic androgen receptor immunoreactivity. Psychoneuroendocrinology 28: 501-512. 315 Goldstone, A.P., Unmehopa, U.A., Swaab, D.F. - Hypothalamic growth hormone-releasing hormone 66

(GHRH) cell number in human illness, Prader-Willi syndrome and obesity. Clin. Endocrinol. 58: 743-755. 316 Hu, X.Y., Qin, S., Lu, Y.P., Ravid, R., Swaab, D.F., Zhou, J.N. - Decreased estrogen receptor-alpha expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients. Acta Neuropathol. (Berl.). 106: 213-220. 317 Huitinga, I., Erkut, Z.A., Van Beurden, D., Swaab, D.F. - Impaired HPA-axis activity and unfavourable disease prognosis with active multiple sclerosis lesions in the hypothalamus. Ann. NY Acad. Sci. vol. 992, 118-129. 318 Ishunina, T.A., Kamphorst, W., Swaab, D.F. - Changes in metabolic activity and estrogen receptors in the human medial mamillary nucleus: relation to sex, aging and Alzheimer s disease. Neurobiol. Aging 24: 817-828. 319 Ishunina, T.A., Van Heerikhuize, J.J., Ravid, R., Swaab, D.F. - Estrogen receptors and metabolic activity in the human tuberomamillary nucleus: changes in relation to sex, aging, and Alzheimer s disease. Brain Res. 988: 84-96 320 Ishunina, T.A., Swaab, D.F. - Increased neuronal metabolic activity and estrogen receptors in the vertical limb of the diagonal band of Broca in Alzheimer s disease: relation to sex and aging. Exptl. Neurol. 183: 159-172 321 Kaiser, S., Kruijver, F.P.M., Sachser, N., Swaab, D.F. - Early social stress in male guinea pigs changes social behaviour, and autonomic and neuroendocrine functions. J. Neuroendocrinol. 15: 761-769. 322 Kaiser, S., Kruijver, F.P.M., Straub, R.H., Sachser, N., Swaab, D.F. - Early social stress in female guinea pigs induces a masculinization of adult behavior and corresponding changes in brain and neuroendocrine function. Behav. Brain Res. 144: 199-210. 323 Kruijver, F.P.M., Balesar, R., Espila, A.M., Unmehopa, U.A., Swaab, D.F. - Estrogen-receptor-β distribution in the human hypothalamus: similarities and differences with ER-α distribution. J. Comp. Neurol. 466: 251-277. 324 Lu, Y.-P., Zeng, M., Hu, X.-Y., Xu, H., Swaab, D.F., Ravid, R., Zhou, J.-N. - Estrogen receptor alphaimmunoreactive astrocytes are increased in the hippocampus in Alzheimer s disease. Exptl. Neurol. 183: 482-488. 325 Luijpen, M.W., Scherder, E.J.A., Van Someren, E.J.W., Swaab, D.F., Sergeant, J.A. - Nonpharmacological interventions in cognitively impaired and demented patients. A comparison with cholinesterase inhibitors. Rev. Neurosci. 14: 343-368. *326 Scherder, E.J.A., Sergeant, J.A., Swaab, D.F. - Pain processing in dementia and its relation to neuropathology. Lancet Neurol. 2: 677-686. 327 Skene, D.J., Swaab, D.F. - Melatonin rhythmicity: effect of age and Alzheimer s disease. Exp. Gerontol. 38: 199-206. 328 Swaab, D.F., Chung, W.C., Kruijver, F.P., Hofman, M.A., Hestiantoro, A. - Sex differences in the hypothalamus in the different stages of human life. Neurobiol. Aging 24 (suppl. 1): S1-16. 329 Swaab, D.F. - Discussion to Sex differences in the hypothalamus in the different stages of human life. Neurobiol. Aging 24 (suppl. 1): S17-S19. 330 Swaab, D.F., Dubelaar, E.J., Scherder, E.J., Van Someren, E.J., Verwer, R. - Therapeutic strategies for Alzheimer disease: focus on neuronal reactivation of metabolically impaired neurons. Alzheimer Dis. Assoc. Disord. 17: S114-22. 331 Van Someren, E.J.W., Riemersma, R., Raymann, R., Swaab, D.F. - Het effect van licht en temperatuur op verstoord slaap-waak-ritme bij ouderen. Psychopraxis 2: 48-50. 332 Verwer, R.W.H., Baker, R.E., Boiten, E.F.M., Dubelaar, E.J.G., Van Ginkel, C.J.M., Sluiter, A.A., Swaab, D.F. - Post-mortem brain tissue cultures from elderly control subjects and patients with a neurodegenerative disease. Exp. Gerontol. 38: 167-172. 333 Wu, Y.-H., Feenstra, M.G.P., Zhou, J.-N., Liu, R.-Y., Torano, J.S., Van Kan, H.J.M., Fischer, D.F., Ravid, R., Swaab, D.F. - Molecular changes underlying reduced Pineal Melatonin levels in Alzheimer s disease; Alterations in Preclinical and Clinical Stages. J. Clin. Endocrin. Metabol. 88: 5898-5906. 334 Zhou, J.N., LIu, R.Y., Van Heerikhuize, J.J., Hofman, M.A., Swaab, D.F. - Alterations in the circadian rhythm of salivary melatonin begin during middle-age. J. Pineal Res. 34: 11-16. 335 Zhou, J.N., Liu, R.Y., Kamphorst, W., Hofman, M.A., Swaab, D.F. - Early neuropathological Alzheimer changes in aged controls accompanied by decreased cerebrospinal fluid melatonin levels. J. Pineal Res. 35: 125-130. 2004 336 Dai, J., Buijs, R.M., Swaab, D.F. - Glucocorticoid hormone (cortisol) affects axonal transport in human cortex neurons but shows resistance in Alzheimer's disease. Brit. J. Pharmacol. 143 (5): 606-610. 67

*337 Dubelaar, E.J., Verwer, R.W., Hofman, M.A., Van Heerikhuize, J.J., Ravid, R., Swaab, D.F. - ApoE epsilon4 genotype is accompanied by lower metabolic activity in nucleus basalis of Meynert neurons in Alzheimer patients and controls as indicated by the size of the Golgi apparatus. J. Neuropathol. Exp. Neurol. 63: 159-169. 338 Erkut, Z.A., Klooker, T., Endert, E., Huitinga, I., Swaab, D.F. - Stress of dying is not suppressed by highdose morphine or by dementia. Neuropsychopharmacology 29: 152-157 339 Hestiantoro, A. and Swaab, D.F. - Changes in estrogen receptor- and - in the infundibular nucleus of the human hypothalamus are related to the occurrence of Alzheimer s disease neuropathology. J. Clin. Endocrinol. Metab. 89: 1912-1925. *340 Huitinga, I., Erkut, Z.A., Van Beurden, D., Swaab, D.F. - Impaired hypothalamus-pituitary-adrenal axis activity and more severe multiple sclerosis with hypothalamic lesions. Ann. Neurol. 55: 37-45. 341 Ishunina, T.A., Kamphorst, W., Swaab, D.F. - Metabolic alterations in the hypothalamus and basal forebrain in vascular dementia. J. Neuropathol. Exptl. Neurol. 63: 1243-1254. 342 Lu, Y.P., Zeng, M., Swaab, D.F., Ravid, R., Zhou, J.N. - Colocalization and alteration of estrogenreceptor-alpha and -beta in the hippocampus in Alzheimer's disease. Hum. Pathol. 35 (3): 275-280. 342 Luijpen, M.W., Swaab, D.F., Sergeant, J.A., Scherder, E.J.A. - Effects of transcutaneous electrical nerve stimulation (TENS) on self-efficacy and mood in elderly with mild cognitive impairment. Neurorehab. & Neural Repair 18: 166-175 343 Salehi, A., Delcroix, J.D., Swaab, D.F. - Alzheimer s disease and NGF signalling. J. Neural Transm. 111: 323-345. 344 Swaab, D.F. - Sexual differentiation of the human brain: relevance for gender identity, transsexualism and sexual orientation. Gynecol. Endocrinol. 19: 301-312. 345 Swaab, D.F. - Neuropeptides in hypothalamic neuronal disorders. Int. Rev. of Cytol. 240: 305-375 346 Van Someren, E.J.W., Swart-Heikens, J., Endert, E., Bisschop, P.H., Swaab, D.F., Bakker, P.J.M., Romijn, J.A., Fliers. E. - Long-term effects of cranial irradiation for childhood malignancy on sleep in adulthood. Eur. J. Endocrinol. 150: 503-510. 2005 347 Alkemade, A., Vuijst, C.L., Unmehopa, U.A., Bakker, O., Wiersinga, W.M., Swaab, D.F., Fliers, E. - Thyroid hormone receptor expression in the human hypothalamus and anterior pituitary. JCEM 90: 904-912. 348 Alkemade, A., Unmehopa, U.A., Wiersinga, W.M., Swaab, D.F., Fliers, E. - Glucocorticoids decrease TRH mrna expression in the paraventricular nucleus (PVN) of the human hypothalamus. JCEM 90: 323-327. 349 Alkemade, A., Friesema, E.C., Kuiper, G.G., Wiersinga, W.M., Swaab, D.F., Visser, T.J., Fliers, E. - Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary. J. Clin. Endocrinol. Metabol. 90: 4322-4334. *350 Bao, A.-M., Hestiantoro, A., Van Someren, E.J.W., Swaab, D.F., Zhou, J.N. - Colocalization of corticotrophin-releasing hormone and estrogen receptor-α in the paraventricular nucleus of the hypothalamus in mood disorders. Brain 128: 1301-1313. 351 Fronczek, R., Lammers, G.J., Balesar, R., Unmehopa, U., Swaab, D.F. - Hypothalamic hypocretin (orexin) system is not affected in Prader-Willi syndrome. J. Clin. Endocr. Metab. 90: 5466-5470. 352 Ishunina, T.A., Van Beurden, D., Van der Meulen, G., Unmehopa, U.A., Huitinga, I., Swaab, D.F. - Diminished aromatase immunoreactivity in the hypothalamus, but not in the basal forebrain nuclei in Alzheimer's disease. Neurobiology of Aging 173-194. *353 Ishunina, T.A., Swaab, D.F., Fischer, D.F. - Estrogen receptor alpha splice variants in the medial mamillary nucleus of Alzheimr's disease patients: identification of a novel MS1 isoform. JCEM. 90: 3757-3765. Submission of sequence data to GenBank, nucleotide sequence bankit651211 AY750962. 354 Luijpen, M.W., Swaab, D.F., Sergeant, J.A., Van Dijk, K.R.A., Scherder, E.J.A. - Effects of transcutaneous electrical nerve stimulation (TENS) on memory in elderly with mild cognitive impairment. Behav. Brain Res. 158: 349-357. 355 Malidelis, Y.I., Panayotacopoulou, M.T., Van Heerikhuize, J.J., Unmehopa, U.A., Kontostavlaki, D.P., Swaab, D.F. - Absence of a difference in the neurosecretory activity of supraoptic nucleus vasopressin neurons of neuroleptic-treated schizophrenic patients. Neuroendocrinology 82: 63-69. 356 Panayotacopoulou, M.T., Malidelis, Y., Van Heerikhuize, J., Unmehopa, U.A., Swaab, D.F. - Individual differences in the expression of tyrosine hydroxylase mrna in neurosecretory neurons of the human paraventricular and supraoptic nuclei: positive correlation with vasopressin mrna. Neuroendocrinology 81: 329-338. 357 Raymann, R., Swaab, D.F., Van Someren, E.J.W. - Cutaneous warming promotes sleep onset. Am. J. 68

Physiol. Regul. Integr. Comp. Physiol. 288: 1589-1597. (Highlights from the literature in Physiology, vol. 20, 2005, p 150-151) 358 Scherder, E., Oosterman, J., Swaab, D.F., Herr, K., Ooms, M., Ribbe, M., Sergeant, J., Pickering, G., Benedetti, F. - Recent developments in pain in dementia. BMJ 330: 461-464. 359 Scherder, E., Oosterman, J.M., Ooms, M.E., Ribbe, M.W., Swaab, D.F. - Chronische pijn bij dementie en bij aandoeningen met een verhoogd risico op cognitieve achteruitgang. Tijdschr. Gerontol. 36: 116-121. 360 Scherder, E.J.A., Wolters, E., Polman, C., Sergeant, J., Swaab, D. - Pain in Parkinson's disease and multiple sclerosis; its relation to the medial and lateral pain systems. Neuroscience and Biobehavioral Rev. 29: 1047-1056. 361 Scherder, E.J.A., Van Paasschen, J., Deijen, J.B., Van der Knokke, S., Orlebeke, J.F., Burgers, I., Devriese, P.P., Swaab, D.F., Sergeant, J.A. - Physical activity and executive functions in the elderly with mild cognitive impairment. Aging & Mental Health 9: 272-280. 362 Swaab, D.F., Bao, A.M., Lucassen, P.J. - The stress system in the human brain in depression and neurodegeneration. Ageing Research Reviews 4: 141-194. 363 Unmehopa, U.A., Van Heerikhuize, J.J., Spijkstra, W., Woods, J.W., Howard, A.D., Zycband, E., Feighner, S.D., Hreniuk, D.L., Palyha, O.C., Guan, X.-M., MacNeil, D.J., Van der Ploeg, L.H.T., Swaab, D.F. - Increased melanin concentrating hormone receptor type I (MCH1R) in the human hypothalamic infundibular nucleus in cachexia. J. Clin. Endocrin. Metab. 90: 2412-2419. 364 Van Someren, E.J.W., Riemersma, R.F., Swaab, D.F. - Licht op het slaap-waakritme bij ouderen en op dementie. State-of-the-art-artikel. Tijdschrift voor Psychiatrie 47: 29-38. 365 Wu, Y.-H., and Swaab, D.F. The human pineal gland and melatonin in aging and Alzheimer s disease. Journal of Pineal Research, 38 (2005) 145-152. 2006 366 Alkemade, A., Friesema, E.C., Kuiper, G.G., Wiersinga, W.M., Swaab, D.F., Visser, T.J., Fliers, E. - Novel neuroanatomical pathways for thyroid hormone action in the human anterior pituitary. Eur. J. Endocrinol. 154: 491-500. 367 Bao, A.M., Fischer, D.F., Wu, Y.H., Hol, E.M., Balesar, R., Unmehopa, U.A., Zhou, J.N., Swaab, D.F. - A direct androgenic involvement in the expression of human corticotropin-releasing hormone. Molec. Psychiatry 11: 567-576. 368 Dubelaar, E.J.G., Mufson, E.J., Ter Meulen, W., Van Heerikhuize, J.J., Verwer, R.W.H., Swaab, D.F. - Increased metabolic activity in nucleus basalis of Meynert neurons in elderly individuals with mild cognitive impairment as indicated by the size of the Golgi apparatus. J. Neuropathol. Exptl. Neurol. 65: 257-266. 369 Eggermont, L., Swaab, D.F., Luiten, P., Scherder, E. - Exercise, cognition and Alzheimer's disease: More is not necessarily better. Neurosci. Biobehav. Rev. 30: 562-575. 370 GIRES (Gender Identity Research and Education Society) - Atypical gender development - a review. Intern. J. Transgenderism, vol. 9, no. 1: 29-44. 371 Hoekert, M., Van der Lek, R.F., Swaab, D.F., Kaufer, D., Van Someren, E.J. - Comparison between informant-observed and actigraph assessments of sleep-wake rhythm disturbance in demented residents of homes for the elderly. Am. J. Geriatr. Psychiatry 14: 104-111. 372 Hofman, M.A., Swaab, D.F. - Living by the clock: the circadian pacemaker in older people. Ageing Research Reviews 5: 33-51. 373 Hoogendijk, W.J.G., Meynen, G., Endert, E., Hofman, M.A., Swaab, D.F. - Increased cerebrospinal fluid cortisol level in Alzheimer's disease is not related to depression. Neurobiol. Aging. 27: 780-781. 374 Kontostavlaki, D.P., Panayotacopoulou, M.T., Sluijs, J.A., Unmehopa, U., Huitinga, I., Hol, E.M., Swaab, D.F. - Co-expression of tyrosine hydroxylase and GTP cyclohydrolase I in arginine vasopressinsynthesizing neurons of the human supraoptic nucleus demonstrated by laser microdissection and realtime PCR. Neuroendocrinology. 84: 386-395. 375 Liu, R.Y., Unmehopa, U.A., Zhou, J.N., Swaab, D.F. - Glucocorticoids suppress vasopressin gene expression in human suprachiasmatic nucleus. J. Steroid Biochem. Mol. Biol. 98: 248-253. 376 Lucassen, P.J., Heine, V.M., Muller, M.B., Van der Beek, E.M., Wiegant, W.M., De Kloet, E.R., Joels, M., Fuchs, E., Swaab, D.F., Czeh, B. - Stress, depression and hippocampal apoptosis. CNS & Neurological Disorders - Drug Targets, 5: 531-546 (Review) 377 Meynen, G., Unmehopa, U.A., Van Heerikhuize, J., Hofman, M.A., Swaab, D.F. - Increased arginine vasopressin mrna expression in the human hypothalamus in depression: a preliminary report. Biol. Psychiatry 60: 892-895. 378 Overeem, S., Verschuuren, J.J., Fronczek, R., Schreurs, L., Den Hertog, H., Hegeman-Kleinn, I.M., Van 69

Duinen, S.G., Unmehopa, U.A., Swaab, D.F., Lammers, G.J. - Immunohistochemical screening for autoantibodies against lateral hypothalamic neurons in human narcolepsy. J. Neuroimmunol. 174: 187-191. 379 Scherder, E.J.A., Van Tol, M.J., Swaab, D.F. - High-frequency cranial electrostimulation (CES) in patients with probable Alzheimer's disease. Am. J. Phys. Med. Rehabil. 85: 614-618. 380 Scherder, E.J.A., Knol, D., Van Tol, M.J., Van Someren, E., Deijen, J.B., Swaab, D., Scheltens, P. (Effects of high-frequency cranial electrostimulation on the rest-activity rhythm and salivary cortisol in Alzheimer's disease. A pilot study. Dement. Geriatr. Cogn. Disord. 22: 267-272. 381 Van de Nes, J.A.P., Konemann, S., Nafe, R., Swaab, D.F. - β-protein/a4 deposits are not associated with hyperphosphorylated tau in somatostatin neurons in the hypothalamus of Alzheimer s disease patients. Acta Neuropathologica 111: 126-138. 382 Van Someren, E.J., Pticek, M.D., Speelman, J.D., Schuurman, P.R. - New actigraph for long-term recording. Mov. Discord.: 21: 1136-1143. 383 Wu, Y.-H., Fischer, D.F., Kalsbeek, A., Garidou-Boof, M.-L., Van der Vliet, J., Pirovano, C., Liu, R.-Y., Zhou, J.-N., Swaab, D.F. - Pineal clock gene oscillation is disturbed in Alzheimer s disease, due to functional disconnection from the "master clock". FASEB J, 20: E1171-E1180. 384 Wu, Y-H., Zhou, J.-N., Balesar, R., Bao, A.-M., Unmehopa, U., Bao, A., Jockers, R., Van Heerikhuize, J.J., Swaab, D.F. - Distribution of MT1 melatonin receptor immunoreactivity in the human hypothalamus and pituitary gland: colocalization of MT1 with vasopressin, oxytocin, and corticotropin-releasing hormone. J. Comp. Neurol. 499: 897-910. 2007 385 Aziz, N.A., Swaab, D.F., Pijl, H., Roos, R.A.C. - Hypothalamic dysfunction and neuroendocrine and metabolic alterations in Huntington's disease: clinical consequences and therapeutic implications. Revs. Neurosci 18: 223-251. 386 Bao, A.M. and Swaab, D.F. - Gender difference in age-related number of corticotropin-releasing hormone-expressing neurons in the human hypothalamic paraventricular nucleus and the role of sex hormones. Neuroendocrinology 85: 27-36 387 Fronczek, R., Overeem, S., Lee, S.Y.Y., Hegeman, I.M., Van Pelt, J., Van Duinen, S.G., Lammers, G.J., Swaab, D.F. - Hypocretin (orexin) loss and sleep disturbances in Parkinson's disease. Brain 131: 1577-1585. 388 Goncharuk, V.D., Buijs, R.M., Swaab, D.F. - Corticotropin-releasing hormone neurons in hypertensive patients are activated in the hypothalamus but not in the brainstem. J. Comp. Neurol. 503: 148-168. 389 Ishunina, T.A., Swaab, D.F., Bogolepova, I.N. - Estrogen receptor α in the hypothalamus and basal forebrain of Alzheimer's disease and vascular dementia cases. Morphological Newsletter, International Morphological Journal, no. 1-2 (in Russian). 390 Ishunina, T.A. and Swaab, D.F. - Alterations in the human brain in menopause. Maturitas 57: 20-22. 391 Ishunina, T.A., Fischer, D.F., Swaab, D.F. - Estrogen receptor alpha and its splice variants in the hippocampus in aging and Alzheimer's disease. Neurobiol. Aging 28: 1670-1681. 392 Meynen, G., Unmehopa, U.A., Hofman, M.A., Swaab, D.F., Hoogendijk, W.J. - Relation between corticotropin-releasing hormone neuron number in the hypothalamic paraventricular nucleus and depressive state in Alzheimer's disease. Neuroendocrinology 85: 37-44. 393 Meynen, G., Unmehopa, U.A., Hofman, M.A., Swaab, D.F., Hoogendijk, W.J. - Hypothalamic oxytocin mrna expression and melancholic depression. Mol. Psychiatry 12: 118-119. 394 Raymann, R.J., Swaab, D.F., Van Someren, E.J. - Skin temperature and sleep-onset latency: changes with age and insomnia. Physiol. Behav. 90: 257-266. 395 Scherder, E., Eggermont, L., Swaab, D., Van Heuvelen, M., Kamsma, Y., De Greef, M., Van Wijck, R., Mulder, T. - Gait in ageing and associated dementias; its relationship with cognition. Neurosci. Biobehav. Rev. 31: 484-497. 396 Scherder, E.J., Vuijk, P.J., Swaab, D.F., Van Someren, E.J. - Estimating the effects of right median nerve stimulation on memory in Alzheimer's disease: a randomized controlled pilot study. Exp. Aging Res. 33: 177-186. 397 Swaab, D.F. - Sexual differentiation of the brain and behavior. Best Pract. Res. Clin. Endocrinol. Metab. 21: 431-444. 398 Verwer, R., Sluiter, A., Balesar, R., Baayen, J., Noske, D., Dirven, C.,Wouda, J., Van Dam, A., Lucassen, P., Swaab, D. - Mature astrocytes in the adult human neocortex express the early neuronal marker doublecortin. Brain 130: 3321-3335. 399 Wu, Y.H. and Swaab, D.F. - Disturbance and strategies for reactivation of the circadian rhythm system in aging and Alzheimer's disease. Sleep Med. 8: 623-636. 70

400 Wu, Y.H., Zhou, J.N., Van Heerikhuize, J., Jockers, R., Swaab, D.F. - Decreased MT1 melatonin receptor expression in the suprachiasmatic nucleus in aging and Alzheimer's disease. Neurobiol. Aging 28: 1239-1247. 401 Wu, Y.H., Fischer, D.F., Swaab, D.F. - A promoter polymorphism in the monoamine oxidase A gene is associated with the pineal MAOA activity in Alzheimer's disease patients. Brain Res. 1167: 13-19. 2008 402 Aziz, N.A., Fronczek, R., Maat-Schieman, M.L.C., Unmehopa, U.A., Roelandse, F.W.C., Overeem, S., Van Duinen, S.G., Lammers, G.J., Swaab, D.F., Roos, R.A.C. - Hypocretin and melanin-concentrating hormone in patients with Huntington disease. Brain Pathology 18: 474-483 403 Bao, A.-M., Meynen, G., Swaab, D.F. - The stress system in depression and neurodegeneration: focus on the human hypothalamus. Brain Res. Rev. 57: 531-553. 404 Bossers, K., Meerhoff, G., Balesar, R., Van Dongen, J.W., Kruse, C.G., Swaab, D.F., Verhaagen, J. - Analysis of gene expression in Parkinson's disease: possible involvement of neurotrophic support and axon guidance in dopaminergic cell death. Brain Pathology 19: 91-107. 405 Fronczek, R., Overeem, S., Lee, S.Y.Y., Hegeman, I.M., Van Pelt, J., Van Duinen, S.G., Lammers, G.J., Swaab, D.F. - Hypocretin (orexin) loss and sleep disturbances in Parkinson's disease. Brain 131, e88. 406 Garcia-Falgueras, A., Swaab, D.F. - A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. Brain 13: 32-46. 407 Goldstone, A.P., Holland, A.J., Hauffa, B.P., Hokken-Koelega, A.C., Tauber, M. et al. - Recommendations for the diagnosis and management of Prader-Willi syndrome. J. Clin. Endocrinol. Metab. 93: 4183-4197. 408 Herbert, Joe. Commentary to Garcia-Falgueras, A., Swaab, D.F., A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. Brain. 409 Ishunina, T.A. and Swaab, D.F. - Age-dependent ERα MB1 splice variant expression in discrete areas of the human brain. Neurobiol. Aging 29: 1177-1189. 410 Ishunina, T.A., Swaab, D.F. - Estrogen receptor-α splice variants in the human brain. Gynecological Endocrinology 24: 93-98 (Review). 411 Raymann, R.J.E.M, Swaab, D.F., Van Someren, E.J.W. - Skin deep: enhanced sleep depth by cutaneous temperature manipulation. Brain 131: 500-513. 412 Riemersma-van der Lek, R.F., Swaab, D.F., Twisk, J., Hol, E.M., Hoogendijk, W.J.G., Van Someren, E.J.G. - Effect of bright light and melatonin on cognitive and noncognitive function in elderly residents. JAMA, Vol. 299, no. 22, 2642-2655. 413 Swaab, D.F. - Sexual orientation and its basis in brain structure and function. PNAS 105, pp. 10273-10274. 414 Wang, S.S., Kamphuis, W., Huitinga, I., Zhou, J.-N., Swaab, D.F. - Depression laser-dissected. Mol. Psychiatry 13: 741. 415 Van Someren, E.J.W., Riemersma-Van der Lek, R.F., Twisk, J., Hol, E.M., Hoogendijk, W., Swaab, D.F. - Symptomatische behandeling bij patiënten met dementie: licht mogelijk wel, maar melatonine niet zinvol. Reactie op ingezonden stuk in Ned. Tijdschr. Geneeskunde 152: 2435. 416 Wang, S.S., Kamphuis, W., Huitinga, I., Zhou, J.-N., Swaab, D.F. - Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances. Mol. Psychiatry 13: 786-799. 417 Wu, L., Sluiter, A.A., Guo, Ho-fu, Balesar, R.A., Swaab, D.F., Zhou, J.N., Verwer, R.W.H. - Neural stem cells improve neuronal survival in cultured postmortem brain tissue from aged and Alzheimer patients. J. Cell. Mol. Med. Vol. 12, no. 5A, pp. 1611-1621. 418 Garcia-Falgueras, A., Swaab, D.F. - A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. (in Turkish). Special Edition, Brain 131: 3132-3146. 2009 419 Chen, X.N., Meng, Q.Y., Bao, A.M., Swaab, D.F., Wang, G.H., Zhou, J.N. - The involvement of retinoic acid receptor-α in corticotropin-releasing hormone gene expression and affective disorders. Biol. Psychiatry 66: 832-839, 2009. 420 Ishunina, T.A., Swaab, D.F. - Hippocampa estrogen receptor-alpha splice variant TADD1 in the human brain in aging and Alzheimer's disease. Neuroendocrinology 89: 187-199, 2009 421 Koning, N., Swaab, D.F., Hoek, R.M., Huitinga, I. - Distribution of the immune inhibitory molecules CD200 and CD200R in the normal central nervous system and multiple sclerosis lesions suggests neuron-glia and glia-glia interactions. J. Neuropathol. Exp. Neurol. 68: 159-167, 2009. 422 Swaab, R.I. and Swaab, D.F. - Sex differences in the effects of visual contact and eye contact in 71

negotiations. J. Exp. Social Psychology 45: 129-136, 2009 423 Swaab, D.F. and Garcia-Falgueras, A. - Sexual differentiation of the human brain in relation to gender identity and sexual orientation. Functional Neurol. 24(1): 17-28, 2009 424 De Rooij, S., Swaab, D.F., Roseboom, T.J., Painter, R.C. - Sexual orientation and gender identity after prenatal exposure to the Dutch famine: a pilot study. Arch. Sex. Behav. 38: 411-416, 2009 425 Eggermont, L.H.P., Swaab, D.F., Hol, E.M., Scherder, E.J.A. - Observation of hand movements by older persons with dementia: Effects on cognition. A pilot study. Dement. Geriatr. Cogn. Disord. 27: 366-374, 2009 426 Eggermont, L.H.P., Swaab, D.F., Hol, E.M., Scherder, E.J.A. - Walking the line. A randomized controlled trial on the effects of a short-term walking program on cognition in dementia. J. Neurol. Neurosurg. Psychiatry 80: 802-804, 2009. 427 Meynen, G., Unmehopa, U.A., Hofman, M.A., Swaab, D.F., Hoogendijk, W.J.G. - Hypothalamic vasopressin and oxytocin mrna expression in relation to depressive state in Alzheimer's disease: a difference with major depressive disorder. J. Neuroendocrinology 21: 722-729. 428 Eggermont, L.H., Swaab, D.F., Knol, D.L., Scherder, E.J. - Hand motor-activity, cognition, mood and the rest-activity rhythm in dementia: a clustered RCT. Behavioural Brain Res. 196: 271-278. 2010 429 Middeldorp, J., Boer, K., Sluijs, J.A., De Filippis, L., Encha-Razavi, F., Vescovi, A.L., Swaab, D.F., Aronica, E., Hol, E.M. - GFAPδ in radial glia and subventricular zone progenitors in the developing human cortex. Development 137: 313-321, 2010 430 Meynen, G., Van Stralen, H., Smit, J.H., Kamphorst, W., Swaab, D.F., Hoogendijk, W.J.G. - Relation between neuritic plaques and depressive state in Alzheimer's disease. Acta Neuropsychiatrica 22: 14-20, 2010 431 Scherder, E., Eggermont, L., Achterberg, W., Plooij, B., Volkers, K., Weijenberg, R., Hooghiemstra, A., Prick, A.E., Pieper, M., Blankevoort, C., Zwakhalen, S., Van Heuvelen, M.J.G., Hamers, J., Lobbezoo, F., Swaab, D., Pot, A.M. - Pijn en bewegen in relatie tot cognitie en gedrag bij dementie. Tijdschrift voor Gerontologie en Geriatrie, jaargang 40, nr. 6, p. 270-278, 2010 432 Kalsbeek, A., Fliers, E., Hofman, M., Swaab, D.F., Buijs, R.M. - Vasopressin and the output of the hypothalamic biological clock. J. Neuroendocrinol. 22: 362-372, 2010 433 Wawrzik, M., Unmehopa, U.A., Swaab, D.F., Van de Nes, J., Buiting, K., Horsthemke, B. - The C15orf2 gene in the Prader-Willi syndrome region is subject to genomic imprinting and positive selection. Neurogenetics 11: 153-161, 2010 434 Bao, A.M., Swaab, D.F. - Corticotrophin-releasing hormone and arginine vasopressin in depression focus on the human postmortem hypothalamus. Vitam. Horm. 82: 339-365, 2010. 435 Middeldorp, J., Boer, K., Sluijs, J.A., De Filippis, L., Encha-Razavi, F., Vescovi, A.L., Swaab, D.F., Aronica, E., Hol, E.M. - GFAP delta in radial glia and subventricular zone progenitors in the developing human cortex. Development 137(2): 313-321, 2010 436 Wawrzik, M. Unmehopa, U.A., Swaab, D.F., Van de Nes, J., Buiting, K., Horsthemke, B. - The C15orf2 gene in the Prader-Willi syndrome region is subject to genomic imprinting and positive selection. Neurogenetics 11(2): 153-161, 2010. 437 Garcia-Falgueras, A., Swaab, D.F. - Sexual hormones and the brain - an essential alliance for sexual identity and sexual orientation. Endocr. Dev. 17: 22-35, 2010. 438 Scherder, E.J.A., Bogen, T., Eggermont, L., Hamers, J.P.H., Swaab, D.F. - The more physical inactivity, the more agitation in dementia. Int. Psychogeriatrics 22:8, 1203-1208. 439 Sprangers, M.A.G., Bartels, M., Veenhoven, R., Baas, F., Martin, N.G., Mosing, M., Movsas, B., Ropka, M.E., Shinozaki, G., Swaab, D., The GENEQOL Consortium Which patient will feel down, which will be happy? The need to study the genetic disposition of emotional states. Qual. Life Res. 19: 1429-1437. 440 Sprangers, M.A.G., Sloan, J.A., Barsevick, A., Chauhan, C., Dueck, A.C., Raat, H., Shi, Q., Van Noorden, C.J.F., The GENEQOL Consortium and D.F. Swaab Scientific imperatives, clinical implications, and theoretical underpinnings for the investigation of the relationship between genetic variables and patient-reported quality-of-life outcomes. Qual. Life Res. 19: 1395-1403. 441 Bossers, K., Wirz, K.T.S., Meerhoff, G.F., Essing, A.H.W., Van Dongen, J.W., Houba, P., Kruse, C.G., Verhaagen, J., Swaab, D.F. Concerted changes in transcripts in the prefrontal cortex precede neuropathology in Alzheimer s disease. Brain 133: 3699-3723. 442 Bao, A.M., Swaab, D.F. Sex differences in the brain, behavior and neuropsychiatric disorders. The Neuroscientist 16: 550-565. 443 Zhou, T., Wang, S.S., Ren, H. Qi, X-R., Luchetti, S., Kamphuis. W., Zou, J.N., Wang, G., Swaab, D.F. Dendritic cell nuclear protein-1, a novel depression-related protein, upregulates corticotropin-releasing 72

hormone expression. Brain, 133: 3069-3079. 2011 444 Goncharuk, V.D., Buijs, R.M., Jhamandas, J.H., Swaab, D.F. - Vasopressin (VP) and neuropeptide FF (NPFF) systems in the normal and hypertensive human brainstem. JCN Res. Systems Neurosci. 519:93-124 445 Meng, Q.Y., Chen, X-N, Zhao, J., Swaab, D.F., Zhou, J.N. Distribution of retinoic acid receptor-α immunoreactivity in the human hypothalamus. Neuroscience 174: 132-142 446 De Fost, M., Van Trotsenburg, A.S.P., Van Santen, H.M., Endert, E., Van den Elzen, C., Kamsteeg, E.J., Swaab, D.F., Fliers, E. Familial neurohypophyseal diabetes insipidus due to a novel mutation in the arginine vasopressin-neurophysin II gene. Eur. J. Endocrinol. 165: 161-165. 447 Liu, J., Hu, P., Qi, X.R., Meng, F.T., Kalsbeek, A., Zhou, J.N. Acute restraint stress increases intrahypothalamic oestradiol concentrations in conjunction with increased hypothalamic oestrogen receptor Beta and aromatase mrna expression in female rats. J. Neuroendocrinol. 23: 435-443. 448 Meynen, G. Swaab, D.F. Why medication in involuntary treatment may be less effective: the placebo/nocebo effect. Medical Hypotheses 77: 993-995. 449 Wang, Q., Joëls, M., Swaab, D.F., Lucassen, P.J. Hippocampal GR expression is increased in elderly depressed females. Neuropharmacology 62: 527-533. 450 Plooij, B., Swaab, D.F., Scherder, E. Autonomic responses to pain in aging and dementie. Rev. Neurosci. 22(5): 583-589. 2012 451 Ishunina, T.A., Swaab, D.F. - Decreased alternative splicing of estrogen receptor-alpha mrna in the Alzheimer's disease brain. Neurobiol. Aging 33: 286-296. 452 Meynen, G., Swaab, D.F., Widdershoven, G. Nocebo and informed consent in the internet era. Am. J. Bioethics 12(3): 1-2, 2012. 453 Zhao, J., Bao, A.-M., Qi, X.-R., Kamphuis, W., Luchetti, S., Lou, J.-S., Swaab, D.F. Gene expression of GABA and glutamate pathway markers in the prefrontal cortex of non-suicidal elderly depressed patients. J. Affect. Dis. 138: 494-502. 455 Shan, L., Bossers, K., Luchetti, S., Balesar, R., Lethbridge, N., Chazot, P.L., Bao, A-M., Swaab, D.F. Alterations in the histaminergic system in the substantia nigra and striatum of Parkinson s patients: a postmortem study. Neurobiol. Aging, 33: 1488e1-e13. 456 Neuronal histamine production remains unaltered in Parkinson s disease despite the accumulation of Lewy bodies and Lewy neurites in the tuberomamillary nucleus. Neurobiol. Aging 33: 1343-1344. 457 Shan, L., Hofman, M.A., Van Wamelen, D.J., Van Someren, E.J.W., Bao, A.-M., Swaab, D.F. Diurnal fluctuation in histidine decarboxylase expression, the rate limiting enzyme for histamine production, and its disorder in neurodegenerative diseases. Sleep 35 (5) : 713-715. 458 Fronczek, R., Van Geest, S., Frölich, M., Roelandse, F.W.C., Lammers, G.J., Swaab, D.F. - Hypocretin (orexin) loss in Alzheimer's disease. Neurobiol. Aging 33: 1642-1650. 459 Rodriguez-Pereira R., Kanhai, H., Rosendaal, F., Van Dommelen, P., Swaab, D.F., Rodigues-Pereira, E., Van de Wetering, B. Parenteral pethidine for labour pain relief and substance use disorder: 20- year follow-up cohort study in offspring. BMJ Open 2012;2:3000719 doi:10.1136/bmjopen 2012 (in press) Ishunina, T.A., Swaab, D.F. - Decreased alternative splicing of estrogen receptor-α mrna in the Alzheimer's disease brain. Neurobiology of Aging. Liu, C.Q., Shan, L., Balesar, R., Luchetti, S., Van Heerikhuize, J.J., Luo, J.H., Swaab, D.F., Bao, A.M. - Quantitative in situ hybridization protocol for formalin-fixed paraffin-embedded human brain material. Methods Scherder, E.J.A., Bouma, A., Van Someren, E.J.W., Swaab, D.F. - Disturbances in behavior and rest-activity rhythm in Alzheimer's disease improve by transcutaneous electrical nerve stimulation (TENS). Int. J. Geriatr. Psychiatr. Swaab, D.F., Bao A-M. - (Re-)activation of neurons in aging and dementia: Lessons from the hypothalamus. Exp. Gerontology, 2010. Goncharuk, V.D., Buijs, R.M., Jhamandas, J., Swaab, D.F. - Vasopressin (VP) and neuropeptide FF (NPFF) systems in the normal and hypertensive human brainstem. J. Comp. Neurol. Scherder, E.J.A., Eggermont, L., Visscher, C., Scheltens, P., Swaab, D.F. - Understanding higher level gait disturbances in mild dementia in order to improve rehabilitation. Neuroscience & Biobehavioral Rev. Alkemade, A., Unmehopa, U., Hessel, E.V.S., Swaab, D.F., Kalsbeek, A., Fliers, E. - Suppressor of cytokine signaling 3 in the human hypothalamus. In press. 73

Alkemade, A., Yi, C.-X., Pei, L., Harakalova, M., Swaab, D.F., La Fleur, S.E., Fliers, E., Kalsbeek, A. AgRP and NPY expression in the human hypothalamic infundibular nucleus correlate with body mass index, whereas changes in αmsh are related to type 2 diabetes. Journal Clin. Endocrin. & Metab. In press. Epub ahead of print. Wijte, D. McDonnell, L.A., Balog, C.I.A., Bossers, K., Deelder, A.M., Swaab, D.F., Verhaagen, J., Mayboroda, O.A. A novel peptidomics approach to detect markers in cerebrospinal fluid of Alzheimer s disease samples. In press. 2012 (submitted/offered/in preparation, accepted) Alkemade, A., Harakalova, M., Swaab, D., Fliers, E., Kalsbeek, A. - Decreased α-melanocyte stimulating hormone (αmsh) expression in the hypothalamic infundibular nucleus of subjects with type 2 diabetes. (submitted) Chung, W.C.J., Balfoort, M., Unmehopa, U., Mobach, D., Lopez, M.J., De Vries, G.J., Swaab, D.F. - Distribution of gonadal steroid receptors in the sexually dimorphic bed nucleus of the stria terminalis during human brain development. (in preparation) Garcia-Falgueras, A., Ligtenberg, L., Kruijver, F.P.M., Swaab, D.F. - Galanin neurons in the sexually dimorphic nucleus of the human preoptic area (SDN-POA) in relation to sex, age, and gender identity. (submitted) Luchetti, S., Bossers, K., Van de Bilt, S., Agrapart, V., Ramirez Morales, V., Frajese, G.V., Swaab, D.F. - Neurosteroid synthesis changes in prefrontal cortex in Alzheimer's disease. Annals of Neurology, submitted. Plooij, B., Eggermont, L.H., Swaab, D.F., Scherder, E.J. - Pain and aerobic physical activity in aging and dementia: are they causally related? (submitted) Plooij, B., Eggermont, L., De Kieviet, J., Swaab, D., Scherder, E. - Relieving chronic musculoskeletal pain; to move or not to move. Rodriguez-Pereira, R., Kanhai, H.H.H., Rosendaal, F.R., Van Dommelen, P., Swaab, D.F., Van de Wetering, B.J.M. - Parenteral opioids for labour pain relief are not linked to substance use disorder of offspring (submitted). Shan, L., Liu, C.-Q., Van Heerikhuize, J., Wu, J.L., Bao, Ai-Min, Swaab, D. - Histamine production: no relationship to Parkinson's disease neuropathology. Submitted to Annals of Neurology. Shan, L., Liu, C-Q., Balesar, R., Van Heerikhuize, J., Swaab, D.F., Bao, A-M. - Histamine production in Parkinson's disease brain: relationship with Lewy bodies and gender. Offered to Brain. Swaab, D.F. and Bao, A. - Effect of age and sex hormones on corticotropin-releasing hormone neurons in the paraventricular nucleus of the human hypothalamus. Brain. (submitted) Swaab, D.F. and Garcia-Falgueras, A. - Letter to the Editor of Perspectives in Biology and Medicine (submitted) Wu, L., Sluiter, A.A., Swaab, D.F., Zhou, J.-N., Verwer, R.W.H. - Neural stem cells improve neuronal survival in cultured postmortem brain tissue from aged patients. (offered) Zhao, X., Zhao, J., Bossers, K., Swaab, D.F., Pei, G. - β-arrestin 1 modulates Alzheimer's disease pathogenesis via promotion of γ-secretase complex formation. Offered. Frijling, J., Yee, J.R., Carter, C.S., Swaab, D.F. The effects of oxytocin and social context on hormone release and neural activation in the paraventricular nucleus of the hypothalamus and dorsal motor nucleus of hte vagus in female praire voles. Zwinderman, A.H., Sprangers, M.A.G., Baas, F., Van Noorden, C.J.F., Radbruch, L., Davies, A., Swaab, D.F., Sloan, J., Kaasa, S., Skorpen, F., Klepstad, P., the GeneQol Consortium Genes selected for their relevance to pain or cachexia are also associated with fatigue and dyspnea: Evidence from the European Pharmacogenetic Opioid Study. Offered Borgers, A.J., Fliers, E., Siljee-Wong, J.E., Swaab, D.F., Van Someren, E., Bisschop, P.H., Alkemade, A. Arginine vasopressin immunoreactivity is decreased in the hypothalamic suprachiasmatic nucleus of subjects with suprasellar tumours. Offered. Friesema, E.C.H., Visser, T.J., Borgers, A.J., Kalsbeek, A., Swaab, D.F., Fliers, E., Alkemade, A. Thyroid hormone transporters and deiodinases in the developing human hypothalamus. Accepted Eur. J. Endocrinology. Melief, J., De Wit, J., Teunissen, C., Uitdehaag, B.M., Swaab, D.F., Huitinga, I. Cortisol relates to disease progression and lesion type in multiple sclerosis. Submitted. Siljee-Wong, J., Unmehopa, U.A., Kalsbeek, A., Swaab, D.F., Fliers, E., Alkemade, A. Melanocortin-4 receptor distribution in the human hypothalamus. Offered. Makris, N, Swaab, D.F., Van der Kouwe, A., Abbs, B., Boriel, D., Handa, R., Tobet, S., Goldstein, J.M. Morphometric parcellation methodology of the human hypothalamus in neuroimaging: validation, normative data and sex differences. Offered to Neuroimage. 74

BOOK CHAPTERS 1970 1 Jongkind, J.F. and D.F. Swaab - Qualitative and quantitative histochemistry of mammalian neurosecretory centers. In: Bargmann and Scharrer: Aspects of Neuroendocrinology, pp. 296-300. Springer, Berlin/ Heidelberg/New York, 1970. 1972 2 Swaab, D.F. - The Hypothalamo-Neurohypophysial System and Reproduction. In: Topics in Neuroendocrinology. Progress in Brain Research, Vol. 38, J. Ariëns Kappers and J.P. Schadé (Eds.), pp.225-244, 1972. 1974 3 Boer, K., G.J. Boer and D.F. Swaab - Does the hypothalamo-neurohypophysial system play a role in gestation length or the course of parturition? In: Integrative Hypothalamic Activity. Progress in Brain Research, Vol. 41, D.F. Swaab and J.P. Schadé (Eds.), pp. 307-319. Elsevier/North-Holland Biomedical Press, Amsterdam, 1974. 4 Swaab, D.F. and W.J. Honnebier - The role of the fetal hypothalamus in development of the fetoplacental unit and in parturition. In: Integrative Hypothalamic Activity. Progress in Brain Research, Vol.41, D.F. Swaab and J.P. Schadé (Eds.), pp. 255-280. Elsevier/North-Holland Biomedical Press, Amsterdam, 1974. 1975 5 Swaab, D.F. - Development of thyroid function and regulation in rat. In: Brain Development and Thyroid Deficiency, A. Querido and D.F. Swaab (Eds.), pp. 19-21. North-Holland Publishing Comp., Amsterdam- New York, 1975. 1976 6 Van Leeuwen, F.W., D.F. Swaab and H.J. Romijn - Light and electron microscopic localization of oxytocin and vasopressin in rats. In: Immunoenzymatic Techniques, INSERM Symposium No. 2, G. Feldmann, P. Druet, J. Bignon and S. Avrameas (Eds.), pp. 345-353. North-Holland Publishing Comp., Amsterdam-Oxford, 1976. 1977 7 Swaab, D.F. and M. Visser - A function for alpha-msh in fetal development and the presence of an alpha-msh like compound in nervous tissue. In: Melanocyte Stimulating Hormone: Control, Chemistry and Effects, F.J.H. Tilders, D.F. Swaab and Tj. B. Van Wimersma Greidanus (Eds.), pp. 170-178. Karger, Basel, 1977. 8 Swaab, D.F., K. Boer and W.J. Honnebier - The influence of the fetal hypothalamus and pituitary on the onset and course of parturition. In: The Fetus and Birth, Ciba Foundation Symposium 47, J. Knight and M. O'Connor (Eds.), pp. 379-400. Elsevier/North-Holland Biomedical Press, Amsterdam-New York, 1977. 9 Visser, M. and D.F. Swaab - Alpha-MSH in the human pituitary. In: Melanocyte Stimulating Hormone: Control, Chemistry and Effects, F.J.H. Tilders, D.F. Swaab and Tj.B. Van Wimersma Greidanus (Eds.), pp.42-45. Karger, Basel, 1977. 1978 10 Corner, M.A., R.E. Baker, N.E. Van de Poll, D.F. Swaab and H.B.M. Uylings (Eds.) - Maturation of the Nervous System. Progress in Brain Research, Vol. 48. Elsevier/North-Holland Biomedical Press, Amsterdam, 1978. 11 Swaab, D.F., K. Boer - Cerebro e hipofisis fetal en el crecimiento intra-uterino y el parto. In: Avances en Obstetricia y Ginecologia, J. Gonzales-Merlo, J. Iglesias Guiu y I. Burzaco (Eds.), pp. 149-158. Salvat Editores, S.A., Barcelona, 1978. 12 Swaab, D.F., G.J. Boer and M. Visser - The fetal brain and intrauterine growth. In: Paediatrics and Growth, D. Barltrop (Ed.), Postgrad. Med. J. 54, Suppl. 1, pp. 63-73, 1978. 13 Swaab, D.F., G.J. Boer, K. Boer, J. Dogterom, F.W. Van Leeuwen and M. Visser - Fetal neuroendocrine mechanisms in development and parturition. In: Maturation of the Nervous System, Progress in Brain Research, Vol. 48, M.A. Corner, R.E. Baker, N.E. Van de Poll, D.F. Swaab and H.B.M. Uylings (Eds.), pp. 277-289. Elsevier/North-Holland Biomedical Press, Amsterdam, 1978. 75

1979 14 Swaab, D.F. and K. Boer - Function of pituitary hormones in human parturition - A comparison with data in the rat. In: Human parturition: New Concepts and Developments, M.J.N.C. Keirse, A.B.M. Anderson and J. Bennebroek Gravenhorst (Eds.), pp. 49-71. Kluwer Acad. Publishers Group, Dordrecht, The Netherlands, 1979. 15 Swaab, D.F., M. Visser and J. Dogterom - The maturity of the foetal brain and its involvement in labour. In: Psychoneuroendocrinology in reproduction, L. Zichella and P. Pancheri (Eds.), pp. 483-495. Elsevier/North-Holland Biomedical Press, Amsterdam, 1979. 1980 16 Boer, G.J., D.F. Swaab, H.B.M. Uylings, K. Boer, R.M. Buijs and D.N. Velis - Neuropeptides in rat brain development. In: Adaptive Capabilities of the Nervous System. Progress in Brain Research, Vol. 53, P. McConnell, G.J. Boer, H.J. Romijn, N.E. Van de Poll and M.A. Corner (Eds.), pp.207-227. Elsevier/North-Holland Biomedical Press, Amsterdam, 1980. 17 Buijs, R.M., D.N. Velis and D.F. Swaab - Extrahypothalamic vasopressin and oxytocin innervation of fetal and adult rat brain. In: Adaptive Capabilities of the Nervous System. Progress in Brain Research, Vol. 53, P. McConnell, G.J. Boer, H.J. Romijn, N.E. Van de Poll, and M.A. Corner (Eds.), pp. 159-167. Elsevier/North-Holland Biomedical Press, Amsterdam, 1980. 18 Swaab, D.F. - Neuropeptides and brain development - a working hypothesis. In: A Multidisciplinary Approach to Brain Development, C. Di Benedetta, R. Balázs, G. Gombos and P. Porcellati (Eds.), pp. 181-196. Elsevier/North-Holland Biomedical Press, Amsterdam, 1980. 19 Swaab, D.F. - Neurohypophysial hormones and their distribution in the brain. In: Hormones and the Brain, D. de Wied and P.A. van Keep (Eds.), pp. 87-100. MTP Press Limited, Lancaster, England, 1980. 20 Swaab, D.F. and K. Boer - Technical developments in the study of neuroendocrine mechanisms in rat pregnancy and parturition. In: Animal Models in Fetal Medicine, P.W. Nathanielsz (Ed.), pp. 169-234. Elsevier/North-Holland Biomedical Press, Amsterdam, 1980. 1981 21 Pévet, P., R.M. Buijs, J. Dogterom, B. Vivien-Roels, F.C. Holder, J.M. Guerné, A. Reinharz, D.F. Swaab, I. Ebels and C. Neacsu - Peptides in the mammalian pineal gland. In: Pineal Function, C.D. Matthews and R.F. Seamark (Eds.), pp. 173-184. Elsevier/North-Holland Biomedical Press, 1981. 22 Swaab, D.F. and J.T. Martin - Functions of alpha-melanotropin and other opiomelanocortin peptides in labour, intrauterine growth and brain development. In: Peptides of the Pars Intermedia, Ciba Foundation Symposium, Vol. 81, D. Evered and G. Lawrenson (Eds.), pp. 196-217. Pitman Medical, London, 1981. 23 Swaab, D.F. and J.P. Ter Borg - Development of peptidergic systems in the rat brain. In: The Fetus and Independent Life, Ciba Foundation Symposium Vol. 86, K. Elliott and J. Whelan (Eds.), pp. 271-294. Pitman Medical, London, 1981. 24 Swaab, D.F., P.W. Achterberg, G.J. Boer, J. Dogterom and F.W. Van Leeuwen - The distribution of MSH and ACTH in the rat and human brain and its relation to pituitary stores. In: Endogenous Peptides and Learning and Memory Processes, J.L. Martinez, R.A. Jensen, R.B. Messing, H. Rigter and J.L. McGaugh (Eds.), pp. 7-36. Academic Press, New York, 1981. 1982 25 Boer, G.J., K. Boer, and D.F. Swaab - On the reproductive and developmental differences within the Brattlebor rat. Ann. N.Y. Acad. Sci. 394, 37-47, 1982. 26 Buijs, R.M., P. Pévet and D.F. Swaab - (Eds.) Chemical Transmission in the Brain: The Role of Amines, Amino Acids and Peptides. Progress in Brain Research, Vol. 55. Elsevier/North-Holland Biomedical Press, Amsterdam, 1982. 27 Swaab, D.F. - Comments on the validity of immunocytochemical methods. In: Cytochemical Methods in Neuroanatomy, V. Chan-Palay and S.L. Palay (Eds.), pp. 423-440. Alan R. Liss, Inc. New York, 1982. 28 Swaab. D.F. - Neuropeptides. Their distribution and function in the brain. In: Chemical Transmission in the Brain. Progress in Brain Research, Vol. 55, R.M. Buijs, P. Pévet and D.F. Swaab (Eds.). pp. 97-122. Elsevier/North-Holland Biomedical Press, Amsterdam, 1982. 29 Swaab, D.F., G.J. Boer, K. Boer, H.P. Oosterbaan and P.R. Oosting - Neurohypophysial and intermediate lobe peptides in intrauterine growth and labour. In: Neuroendocrinology of Vasopressin, Corticoliberin and Opiomelanocortins, A.J. Baertschi and J.J. Dreifuss (Eds.), pp. 343-352. Academic Press, London, 1982. 76

1983 30 Boer, G.J. and D.F. Swaab - Long-term effects on brain and behavior of early treatments with neuropeptides. In: Application of Behavioral Pharmacology in Toxicology, G. Zbinden, V. Cuomo, G. Racagni and B. Weiss (Eds.), pp. 251-263. Raven Press, New York, 1983. 31 Boer, K. and D.F. Swaab - Oxytocine en de baring. In: Voortgang en Visie. 25 jaar Verloskunde en Gynaecologie. Bundel aangeboden aan Prof. Dr. G.J. Kloosterman bij zijn afscheid als hoogleraar aan de UvA, onder redactie van P.E. Treffers, M.F. Schutte, O.P. Bleker, D. van Alten J.V.Th.H. Hamerlynck en J.H. van Wering. Bohn, Scheltema en Holkema, Utrecht/Antwerpen, pp.216-226, 1983. 32 Buijs, R.M., G.J. de Vries, F.W. van Leeuwen and D.F. Swaab - Vasopressin and oxytocin: distribution and putative functions in the brain. In: The Neurohypophysis: Structure, Function and Control. Progress in Brain Research, Vol. 60, B.A. Cross and G. Leng (Eds.), pp.115-122. Elsevier/North-Holland Biomedical Press, Amsterdam, 1983. 33 Pool, Ch.W., R.M. Buijs, D.F. Swaab, G.J. Boer and F.W. van Leeuwen - On the way to a specific immunocytochemical localization. In: Immunohistochemistry, A.C. Cuello (Ed.), IBRO Handbook Series `Methods in Neurosciences', pp.1-46. John Wiley and Sons, Ltd., New York/London, 1983. 34 Swaab, D.F. and M. Mirmiran - Possible mechanisms underlying the teratogenic effects of medicines of the developing brain. In: Proc. EFCNS Congress, `Prenatal Development Disturbances', pp.127-156, 1983. Pre-published in TCCD, Vol. 6, May 1983. 1984 35 Swaab, D.F. and M.A. Hofman - Sexual differentiation of the human brain. A historical perspective. In: Sex Differences in the Brain. Relation between Structure and Function. Progress in Brain Research, Vol. 61., G.J. de Vries et al. (Eds.), pp. 361-374. Elsevier/North-Holland Biomedical Press, Amsterdam, 1984. 36 Swaab, D.F., H.P. Oosterbaan, R. Ravid and M.A. Hofman - Parturition as an outcome of fetal neuroendocrine stimuli superimposed upon an inherent metabolic mechanism. In: Research in Perinatal Medicine II. "Fetal Neuroendocrinology", F. Ellendorff, P.D. Gluckman and N. Parvizi (Eds.), pp. 259-274. Perinatology Press, Ithaca, New York, 1984. 37 Swaab, D.F. and M. Mirmiran - Possible mechanisms underlying the teratologic effects of medicines on the developing brain. In: Neurobehavioral Teratology, J. Yanai (Ed.), pp. 55-71. Elsevier/North-Holland Biomedical Press, Amsterdam, 1984. 38 Swaab, D.F., E. Fliers and B. Fisser - The vasopressin containing neuron in the human brain; changes during aging and senile dementia. Proceedings of the EURAGE Workshop on "Aging of the brain and senile dementia: the inventory of EEC potentialities", D.L. Knook, G. Calderini and L. Amaducci (Eds.), pp. 71-78, 1984. 1985 39 Fliers, E., W.A. Van Gool, F.P.A.J. Van Haaren, M. Mirmiran and D.F. Swaab - Meeting Report: Aging of the Brain and Senile Dementia. 14th International Summer School of Brain Research, Amsterdam, August 26-30, Neurobiol. Aging 6, 341-344, 1985. 40 Oosterbaan, H.P., D.F. Swaab and G.J. Boer - The origin of amniotic oxytocin and vasopressin and their relationship to intra-uterine growth. In: The Physiological Development of Fetus and Newborn, C.T. Jones and P.W. Nathanielsz (Eds.), pp. 89-92. Academic Press, London, 1985. 41 Swaab, D.F. - Report of the Study Group No. 11 of the World Congr. by the UNIPEI, `Influence of fetal and neonatal environment on physical, psychological and intellectual development'. In: `Prevention of Physical and Mental Congenital Defects', In: Epidemiology, Early Detection and Therapy, and Environmental Factors, M. Marois (Ed.), pp. 463-467. Alan R. Liss. Inc., New York, 1985. 42 Swaab, D.F. and M. Mirmiran - The influence of chemicals and environment on brain development. In: `Behavioral Teratology'. Proc. World Congr. UNAPEI, `Prevention of Physical and Mental Congenital Defects', In: M. Marois (Ed.), Epidemiology, Early Detection and Therapy, and Environmental Factors, pp. 447-451. Alan R. Liss Inc., New York, 1985. 1986 43 Fliers, E. and D.F. Swaab - Neuropeptide changes in aging and Alzheimer's disease. In: Aging of the Brain and Alzheimer's Disease. Progress in Brain Research, Vol.70, D.F. Swaab et al. (Eds.), Elsevier Biomed. Press, Amsterdam, pp. 141-152, 1986. 44 Ravid, R., Swaab, D.F., Fliers, E. and Hoogendijk, J.E. - Increased vasopressin production in senescence and dementia due to kidney changes. In: Alzheimer's and Parkinson's Disease: Strategies for Research and Development, A. Fisher, I. Hanin and C. Lachman (Eds.). Plenum Press/New York, 77

pp.121-127, 1986. 45 Swaab, D.F. - Aging and circadian rhythms. In: Boerhaave Commissie voor Postacademisch Onderwijs in de Geneeskunde `De Biologische Klok', pp.63-68, 1986. 46 Swaab, D.F. and E. Fliers - Clinical strategies in the treatment of Alzheimer's disease. In: Aging of the Brain and Alzheimer's Disease. Progress in Brain Research, Vol.70, D.F. Swaab et al. (Eds.). Elsevier Biomedical Press, Amsterdam, pp.413-427, 1986. 47 Swaab, D.F. and M. Mirmiran - Mechanisms underlying the behavioral teratogenic effects of chemicals on the developing brain. In: Child Development and Learning Behaviour. Proc. 2nd Eur. Symp. on Developmental Neurology, 1985 Hamburg, pp.417. I. Flehming and L. Stern (Eds.), Gustav Fischer Verlag, Stuttgart/New York, 1986. 48 Swaab, D.F. and M. Mirmiran - Functional teratogenic effects of chemicals on the developing brain. Monographs in Neuronal Sciences. M.M. Cohen (Ed.), In: `Systemic Hormones, Neurotransmitters and Brain Development', G. Dörner, S.M. McCann and L. Martini (Eds.), pp. 457, 1986. 49 Swaab, D.F., E. Fliers and W.A. van Gool - Immunocytochemical localization of vasopressin in the human brain; its possible consequences for therapeutic strategies in aging and dementia. In: Psychiatric Disorders: Neurotransmitters and Neuropeptides, J.M. van Ree and S. Matthysse (Eds.). Progress in Brain Research, Vol.65, Elsevier Science Publishers BV, Biomedical Division, Amsterdam, pp. 105-113, 1986. 50 Swaab, D.F., E. Fliers and E. Goudsmit - Differential cell loss in (peptide) neurons in the hypothalamus anterior with aging and Alzheimer's disease: Lack of changes in cell density. In: Neurology, K. Poeck, H.J. Freund and H. Gänshirt (Eds.), Springer-Verlag, Berlin, Heidelberg, pp.119-125, 1986. 51 Swaab, D.F., E. Fliers and R. Ravid - The vasopressin neuron in the aging human and rat brain. CRC Handbook of Comparative Opioid and Related Neuropeptide Mechanisms, Vol. II. G.B. Stefano (Ed.), CRC Press, Boca Raton, pp.221-230, 1986. 52 Swaab, D.F., E. Fliers, E. Goudsmit and H.B.M. Uylings - Brain sampling and preservation of specimens from Alzheimer patients and controls for morphology. In: Modern Trends in Aging Research. Y. Courtois et al. (Eds.), Coll. INSERM-EURAGE, John Libbey Eurotext Ltd., pp.413-420, 1986. 53 Swaab, D.F., E. Fliers, J.E. Hoogendijk and R. Ravid - Peptiden in de menselijke hersenen; vasopressine in relatie tot veroudering en dementie. In: Neuropeptiden. Hersenen, Gedrag en Verslaving, J. Joosse en P.E. Voorhoeve (Eds.). Pudoc, Wageningen, pp.126-145, 1986. 1987 54 Fliers, E. and D.F. Swaab - Een hersenbank ten behoeve van onderzoek naar de ziekte van Alzheimer. Geriatrie-informatorium, L1105/7 - L1105/11, november 1987. 55 Swaab, D.F. - EURAGE inventory of research on `aging of the brain and dementia in the Netherlands'. In: EEC Concerned Action on Cellular Ageing and Diseases, EURAGE-report, Amsterdam, 1987. 56 Swaab, D.F., E. Fliers and J.E. Hoogendijk - Vasopressin in relation to human aging and dementia. In: Vasopressin: Principles and Properties, D.M. Gash and G.J. Boer (Eds.). Plenum Press, New York, pp. 611-625, 1987. 57 Swaab, D.F., B. Roozendaal, R. Ravid, D.N. Velis, L. Gooren and R. Williams - Suprachiasmatic nucleus in aging, Alzheimer's disease, transsexuality and Prader-Willi syndrome. In: Neuropeptides and Brain Function. E.R. de Kloet, V.M. Wiegant and D. de Wied (Eds.), Progress in Brain Research, Vol.72, Elsevier Biomedical Press, pp.301-310, 1987. 58 Swaab, D.F. and H.B.M. Uylings - Potentialities and pitfalls in the use of human brain material in molecular neuroanatomy. Manual ETP/ENA/IBRO practical course Molecular Neuroanatomy, Amsterdam, June 15-19, pp.549-566, 1987. 1988 59 Boer, G.J., F.G.M. Snijdewint and D.F. Swaab - Neuropeptides and functional neuroteratology. In: Biochemical Basis of Functional Neuroteratology: permanent effects of chemicals on the developing brain. Progr. Brain Res., Vol.73, G.J. Boer, M.G.P. Feenstra, M. Mirmiran, D.F. Swaab and F. Van Haaren (Eds.), Elsevier Biomed. Press, Amsterdam, pp. 243-264, 1988. 60 Goudsmit, E. and D.F. Swaab - Dementie en de ziekte van Alzheimer. Spectrum Jaarboek, 339-342, 1988. 61 Goudsmit, E., E. Fliers and D.F. Swaab - Hersenveroudering en de ziekte van Alzheimer. Geriatrie Informatorium 15, D 1015-14, March, 1988. 62 Mirmiran, M. and D.F. Swaab - Drugs and Behavioral Development. Handbook of Human Growth and Developmental Biology, Vol.1, Part C: Factors Influencing Brain Development. E. Meisani and P. Timiras (Eds.), CRS Press, Florida, pp. 125-137, 1988. 78

63 Swaab, D.F. - Hersenen en postmenopauze. Proceedings van "De medicalisering van de postmenopauze", Academisch Medisch Centrum, 23 maart, Amsterdam, p. 15-21, 1988. 64 Swaab, D.F. and M. Mirmiran - Permanent effects of chemicals on the developing brain; Functional and behavioral teratology. In: Fetal and Neonatal Neurology and Neurosurgery, M. Levene, M.J. Bennett and J. Punt (Eds.), Churchill Livingstone, Edinburgh, UK, pp. 258-264, 1988. 65 Swaab, D.F., G.J. Boer and M.G.P. Feenstra - Concept of functional neuroteratology and the importance of neurochemistry. In: Biochemical Basis of functional Neuroteratology: permanent effects of chemicals on the developing brain. Progr. Brain Res., Vol.73, G.J. Boer, M.G.P. Feenstra, M. Mirmiran, D.F. Swaab and F. Van Haaren (Eds.), Elsevier Biomed. Press, Amsterdam, pp. 3-14, 1988. 66 Swaab, D.F. and H.B.M. Uylings - Potentialities and pitfalls in the use of human brain material in molecular neuroanatomy. In: Molecular Neuroanatomy, F.W. Van leeuwen, R.M., Buijs, Chr.W. Pool and O. Pach (Eds.), Elsevier Science Publishers, Amsterdam, pp. 403-416, 1988. 1989 67 Goudsmit, E., E. Fliers and D.F. Swaab - Changes in vasopressin neurons and fibers in aging and Alzheimer's disease: reversibility in the rat. Alzheimer's disease and Related Disorders. Progress in Clinical and Biological Research 317, 1193-1208, 1989, Alan R. Liss, Inc., New York. 68 Goudsmit, E. and D.F. Swaab, Neuroendocrine aspects of normal and pathological aging. In: Recent advances in basic and clinical neuroendocrinology (eds. F.F. Casanueva, C. Dieguez), 1989, Elsevier Publisher, 369-382. 69 Honnebier, M.B.O.M., D.F. Swaab and M. Mirmiran - Diurnal rhythmicity during early human development. In: Development of circadian rhythmicity and photoperiodism in mammals. (ed. S.M. Reppert), Perinatology Press, Ithaca, NY, 221-244, 1989. 70 Swaab, D.F. - De klok in onze hersenen. Lecture for "Koninklijke Maatschappelijke Diligentia", Natuurkundige Voordrachten, Nieuwe Reeks No. 67, W.P. van Stokkum & Zn., The Hague, 93-102, 1989. 71 Swaab, D.F. and R. Ravid - The brain's defence mechanisms against aging and dementia. In: The Future of Psychogeriatrics, Eds. D.H. Sipsma and L.M. Punt, pp.83-99, 1989. 1990 72 De Jonge F.H., D.F. Swaab, M.P. Ooms, E. Endert, N.E. Van de Poll - Developmental and functional aspects of the human and rat sexually dimorphic nucleus of the preoptic area (SDN-POA). In: Hormones, Brain and Behavior in Vertebrates I. Sexual differentiation, Neuroanatomical Aspects, Neurotransmitters and Neuropeptides. Comparative Physiology vol. 8. J. Balthazart (Ed.), Karger AG, Basel, pp. 121-136, 1990. 73 Goudsmit, E., E. Fliers and D.F. Swaab - Ageing of the brain and Alzheimer's disease. In: Gerontology - Approaches to biomedical and clinical research (eds. M.A. Horan and A. Brouwer), Edward Arnold, Hodder & Stoughton, London/Melbourne/ Auckland, pp. 165-203, 1990. 74 Goudsmit, E. and D.F. Swaab - Activation of neuronal systems with aging and in Alzheimer's disease. In: From Gene to Man - Gerontological Research in the Netherlands (eds. C.F.A. van Bezooijen, R. Ravid, A.A.J. Verhofstad) 62-65, Stichting Gerontologie en Geriatrie, Rijswijk, 1990. 75 Kremer, H.P.H., R.A.C. Roos, G.Th.A.M. Bots and D.F. Swaab - The hypothalamic lateral tuberal nucleus in Huntington's disease and Alzheimer's disease. In: From Gene to Man - Gerontological Research in the Netherlands (eds. C.F.A. van Bezooijen, R. Ravid, A.A.J. Verhofstad) 137-139, Stichting Gerontologie en Geriatrie, Rijswijk, 1990. 76 Mullaart, E., M.E.T.I. Boerrigter, R. Ravid, D.F. Swaab and J. Vijg - Accumulation of DNA damage in cerebral cortex of Alzheimer's disease patients. In: From Gene to Man - Gerontological Research in the Netherlands (eds. C.F.A. van Bezooijen, R. Ravid, A.A.J. Verhofstad) 337-340, Stichting Gerontologie en Geriatrie, Rijswijk, 1990. 77 Oosterbaan, H.P., D.F. Swaab and R. Ravid - The fetal brain and parturition. The possible function of endocrine systems and energy balance. In: Handbook of Human Biological Development, Part B: Growth, Nutrition and Metabolism, E. Meisami and P. Timiras (Eds.), CRC Press, Inc., Boca Raton, Florida, USA, p.39-51, 1990. 78 Ravid, R. and D.F. Swaab - De Nederlandse Hersenbank - op weg naar gezond verstand. In: Ouder worden nu '90 (eds. C.P.M. Knipscheer, J.J.M. Michels, M.W. Ribbe), Versluys, Almere, pp. 279-284, 1990. 79 Ravid, R. and D.F. Swaab - The Netherlands Brain Bank. In: From Gene to Man: Gerontological Research in the Netherlands" (eds. A.A.J. Verhofstad, C.F.A. van Bezooijen, R. Ravid), 55-59, Stichting Gerontologie en Geriatrie, Rijswijk, 1990. 79

80 Ravid, R., E.J. van Zwieten, D.F. Swaab and Tj.P. Van der Woude - Light microscopic immunocytochemical localization of vasopressin binding sites in the vascular bed of the rat brain, Proceedings IVth International Conference on the Neurohypophysis, Copenhagen 2-5 July, Oxford University Press, 124-129, 1990. 81 Swaab, D.F. - Strategie voor hersenonderzoek betreffende veroudering en de ziekte van Alzheimer. In: Gerontologie en Wetenschap, D.J.B. Ringoir and C.J.J. Tempelman (Eds.), NIG, Nijmegen, pp. 75-87, 1990. 82 Swaab, D.F. - Aging and dementia research in the Netherlands Institute for Brain Research (NIBR) In: From Gene to Man - Gerontological Research in the Netherlands (eds. C.F.A. van Bezooijen, R. Ravid, A.A.J. Verhofstad) 53-54, Stichting Gerontologie en Geriatrie, Rijswijk, 1990. 83 Swaab, D.F., E. Goudsmit, M.A. Hofman, M.B.O.M. Honnebier, W. Kamphorst, R. Ravid, D. Troost - Lifespan changes in vasopressin neurons in the suprachiasmatic nucleus of the human hypothalamus. Proceedings IVth International Conference on the Neurohypophysis, Copenhagen 2-5 July, Oxford University Press, 130-134, 1990. 84 Van Zwieten, E.J., R. Ravid and D.F. Swaab - Post-Mortem effects on vasopressin producing neurons in the Wistar rat. In: From Gene to Man -Gerontological Research in the Netherlands (eds. C.F.A. van Bezooijen, R. Ravid, A.A.J. Verhofstad) 66-68, Stichting Gerontologie en Geriatrie, Rijswijk, 1990. 85 Witting, W., M. Mirmiran, D.F. Swaab, I.H. Kwa and P. Eikelenboom - Alterations in the circadian restactivity rhythm in aging and Alzheimer's disease. In: From Gene to Man - Gerontological Research in the Netherlands (eds. C.F.A. van Bezooijen, R. Ravid, A.A.J. Verhofstad) 60-61, Stichting Gerontologie en Geriatrie, Rijswijk, 1990. 1991 86 Mirmiran, M., W. Witting, D.F. Swaab, P. Eikelenboom and W.A. Van Gool - Sleep and circadian rhythm changes in Alzheimer's disease. In: Smirne, S., Franceschi, M. and Ferini-Strambi, L. (Eds.) Sleep and Ageing. Proceedings of the second Milano International Symposium on Sleep, Masson, Milano, pp. 57-64, 1991. 87 Ravid, R., J. van Heerikhuize, D.F. Swaab, W. Kamphorst, H.J. Haigler, B.E. Miller and H.A. Ghanbari - Temporal-frontal differences in Alzheimer's disease associated proteins: A biochemical study. In: K. Iqbal, D.R.C. McLachlan, B. Winblad and H.M. Wisniewski (Eds.) Alzheimer's Disease: Basic Mechanisms, Diagnosis and Therapeutic Strategies, John Wiley & Sons Ltd., New York, pp. 577-579, 1991. 88 Swaab, D.F. - Relation between maturation of neurotransmitter systems in the human brain and psychosocial disorders. Biological Risk Factors for psychological disorders. eds. M. Rutten and P. Casaer, Cambridge Univ. Press, Cambridge, pp. 50-66, 1991. 89 Swaab, D.F., P. Eikelenboom, I. Grundke-Iqbal, K. Iqbal, H.P.H. Kremer, R. Ravid, and J.A.P. van de Nes - Cytoskeletal alterations in the hypothalamus during aging and in Alzheimer's disease are not necessarily a marker for impending cell death. In: K. Iqbal, D.R.C. McLachlan, B. Winblad and H.M. Wisniewski (Eds.), Alzheimer's Disease: Basic Mechanisms, Diagnosis and Therapeutic Strategies, John Wiley & Sons Ltd., New York, pp. 181-190, 1991. 90 Swaab, D.F. and R. Ravid - Biochemical markers for Alzheimer's disease. Proceedings 7th International Meeting of Alzheimer's Disease International, Amsterdam, 23-25 September 1991, pp.121-134. 1992 91 Goudsmit, E., A. Neijmeijer-Leloux and D.F. Swaab - The human hypothalamo-neurohypophyseal system in relation to development, aging and Alzheimer's disease. In D.F. Swaab, M.A. Hofman, M. Mirmiran, R. Ravid and F.W. van Leeuwen (Eds.) The human hypothalamus in health and disease. Progress in Brain Research Vol. 93, Elsevier, Amsterdam, 237-248. 92 Hofman, M.A. and D.F. Swaab - The human hypothalamus: comparative morphometry and photoperiodic influences. In D.F. Swaab, M.A. Hofman, M. Mirmiran, R. Ravid and F.W. van Leeuwen (Eds.) The human hypothalamus in health and disease. Progress in Brain Research Vol. 93, Elsevier, Amsterdam, 133-149. 93 Mirmiran, M. and D.F. Swaab - Effects of perinatal medication on the developing brain. In: J.G. Nijhuis (Ed.), Fetal Behaviour: Development and Perinatal aspects, Oxford University Press, Oxford, pp. 112-125. 94 Mirmiran, M., D.F. Swaab, J.H. Kok, M.A. Hofman, W. Witting and W.A. Van Gool - Circadian rhythms and the suprachiasmatic nucleus in perinatal development, aging and Alzheimer's disease. In D.F. Swaab, M.A. Hofman, M. Mirmiran, R. Ravid and F.W. van Leeuwen (Eds.) The human hypothalamus in health and disease. Progress in Brain Research Vol. 93, Elsevier, Amsterdam, 151-163. 80

95 Ravid, R., E.J. van Zwieten and D.F. Swaab - Brain banking and the human hypothalamus - factors to match for, pitfalls and potentials. In D.F. Swaab, M.A. Hofman, M. Mirmiran, R. Ravid and F.W. van Leeuwen (Eds.) The human hypothalamus in health and disease. Progress in Brain Research Vol. 93, Elsevier, Amsterdam, 83-95. 96 Swaab, D.F., L.J.G. Gooren and M.A. Hofman - The human hypothalamus in relation to gender and sexual orientation. In D.F. Swaab, M.A. Hofman, M. Mirmiran, R. Ravid and F.W. van Leeuwen (Eds.) The human hypothalamus in health and disease. Progress in Brain Research Vol. 93, Elsevier, Amsterdam, 205-219. 97 Swaab, D.F., E. Goudsmit, H.P.H. Kremer, M.A. Hofman and R. Ravid - The human hypothalamus in development, sexual differentiation, aging and Alzheimer's disease. In A. Ermisch, R. Landgraf and H.- J. Rühle (Eds.), Progress in Brain Research Vol. 91, Elsevier, Amsterdam, pp. 465-472. 98 Swaab, D.F., M.B.O.M. Honnebier and M. Mirmiran - Development of the central nervous system and its relationship to fetal behavior: the fetal suprachiasmatic nucleus and circadian rhythms. In: Foetal Behaviour: Developmental and Perinatal Aspects. J. Nijhuis (Ed.), Oxford University Press, Oxford, p. 75-90, 1992. 99 Swaab, D.F. In: Professoren A/Z, UvA 1992. 100 Swaab, D.F., E. Goudsmit, H.P.H. Kremer, R. Ravid and W. Witting - Neuroendocrine changes i n aging and Alzheimer's disease. Neurodevelopment, Aging and Cognition. I. Kostovi, S. Kn e e v i, H.M. Wisniewski and G.J. Spillich (eds.) Birkhäuser, Boston, 1992, pp. 227-237. 1993 101 Cacabelos, R., Hofman, A., Mullan, M., Ferris, S.H., Portera, A., Frey, H., Swaab, D.F., de Leon, M., Terry, R., Masters, C.L., Iqbal, K., Wisniewski, H.M., Takeda, M., Giacobini, E., Nordberg, A. and Winblad, B. - Alzheimer's disease: Scientific progress for future trends. Drug News and Perspectives, vol. 6(4): 242-244. 102 Hofman, M.A. and Swaab, D.F. - Effects of light and ageing on the human suprachiasmatic nucleus. In: H. Nakagawa, Y. Oomura and K. Nagai (eds.) New Functional Aspects of the Suprachiasmatic Nucleus of the Hypothalamus. John Libbey and Co. Ltd., pp. 207-217, 1993. 103 Ravid, R. and D.F. Swaab - The importance of brain banking in Parkinson's disease. In: E.Ch. Wolters and Philip Scheltens (Eds.) Mental Dysfunction, Vrije Universiteit Amsterdam, pp. 381-396. 104 Swaab, D.F. - De baring als een samenspel tussen regulerende factoren uit de foetale en moederlijke hersenen. Proceedings Papendalsymposium "Fysiologie van de zwangerschap", 1993. 105 Swaab, D.F. - The fetal brain and intrauterine growth retardation. In: Perinatal aspects of growth retardation, K. Boer, J. Kok, H. Wolf and H. Zondervan (Eds.), Amsterdam University Press, pp. 131-137, 1993. 106 Swaab, D.F., M.A. Hofman, M. Mirmiran, E.J.W. Van Someren and J.N. Zhou -Development and Aging of the biological clock. Boerhaave Course: De Biologische Klok; praktische toepassingen in kliniek en huisartsenpraktijk", Eds. Prof. dr. W.J. Rietveld en Dr. G.A. Kerkhof, Univ. of Leiden, Oktober 7-8, pp. 9-23. 107 Van Zwieten, E.J., R. Ravid and D.F. Swaab - Unchanged vasopressin innervation of the locus coeruleus in Alzheimer's disease. In: Alzheimer's Disease: Advances in Clinical and Basic Research. B. Corain, K.Iqbal, M. Nicolini, B. Winblad, H. Wisniewski and P. Zatta (Eds.), John Wiley and Sons Ltd, 1993. 108 Witting, W., M. Mirmiran, P. Eikelenboom, I.H. Kwa and D.F. Swaab - Circadian rest-activity rhythm monitoring in aging and Alzheimer's disease. In: Geriatric Psychiatry abd New Technologies. M. Kalousek (Ed.) Janssen Publishers, Neuss, pp. 281-292. 1994 109 Swaab, D.F. and Hofman, M.A. - Age, sex and light: variability in the human suprachiasmatic nucleus (SCN) in relation to its function. In: Neuroscience: From the Molecular to the Cognitive, F. Bloom (Ed.), Progress in Brain Research, Vol. 100, chapter 32, Elsevier, Amsterdam, pp. 261-265. 110 Swaab, D.F., Hofman, M.A., Mirmiran, M., Van Someren, E.J.W. and Zhou, J.N. - The human suprachiasmatic nucleus (SCN) in a periodic environment. Proceedings of the fifth Sapporo Symposium of Biological Rhythm, Sapporo, Japan, pp. 323-337, Hokkaido University Press. 111 Van Someren, E.J.W., C. Lijzenga, M. Mirmiran and D.F. Swaab - Effect of physical activity on the circadian system in the elderly. In: Environment and Physiology, B.N. Mallick and R. Singh (Eds.), Narosa Publishing House, New Delhi, India, chapter 15, pp. 153-163. 1995 81

112 Raadsheer, F.C., Kamphorst, W., Purba, J.S., Ravid, R., Tilders, F.J.H. and Swaab, D.F. - Hyperactivity of the hypothalamo-pituitary-adrenal axis may contribute to depression rather than to dementia. In: Cacabelos, R., Frey, H., Nishimura, T. and Winblad, B. (Eds). Neurogerontology and Neurogeriatrics, vol. 1, pp. 51-59, 1995 113 Ravid, R., Swaab, D.F., Van Zwieten, E.J. and Salehi, A. - Controls are what makes a brain bank go round. In: Cruz-Sánchez, F.F., Ravid, R., and Cuzner, L. (Eds.) Neuropathological diagnostic criteria for brain banking. IOS Press, Amsterdam, 1995, pp. 4-13. 114 Ravid, R., Swaab, D.F., Kamphorst, W. and Van Zwieten, E.J. - A golden standard protocol for the brain banking society? The Amsterdam experience. In: Cruz-Sanchez, F.F., Cuzner, M.L., and Ravid, R. (Eds.) Neuropathological Diagnostic Criteria for Brain Banking, J. of Neuropathol. & Exptl. Pathol. 54. Suppl. 25S-26S. 115 Ravid, R. and Swaab, D.F. - Brain banking in Alzheimer's disease: pitfalls and potentials. Neuropathol. Appl. Neurobiol. 21: 18-19, 1995. 116 Swaab, D.F., Kamphorst, W., Raadsheer, F.C., Purba, J.S., Ravid, R. and Tilders, F.J.H. - Increased hypothalamo-pituitary-adrenal (HPA) axis activity is not pivotal in the pathogenesis of Alzheimer's disease. In: K. Iqbal, A. Mortimer, B. Winblad and H.M. Wisniewski (eds.) Research Advances in Alzheimer's disease and related Disorders. pp. 461-466. John Wiley & Sons Ltd. 1995. 117 Swaab, D.F., K. Boer and M. Mirmiran - Long-term functional teratogenic effects of chemicals on the developing brain. In: Levene, M.I., Lilford, R.J., Bennett, M.J., Punt, J. (Eds.) Fetal and Neonatal Neurology and Neurosurgery, pp. 263-277, Churchill Livingstone, Edinburgh. 118 Swaab, D.F. - The human hypothalamus in aging and dementia. In: Scherbaum, W.A., Rossmanith, W.G. (Eds.) The Endocrinology of Aging. pp. 1-14. Walter de Gruyter, Berlin. 119 Zhou, J.N. and Swaab, D.F. - Age-related changes in neuropeptidergic neurons in the human hypothalamus. In: Macieira-Coelho, A. (Ed.). Molecular basis of aging. CRC Press, Boca Raton, 1995, pp. 528-552. 1996 120 Swaab, D.F., Zhou, J.N., Fodor, M. and Hofman, M.A. - Gender- and sexual orientation-related differences in the human hypothalamus. In: I. Hughes (Ed.) Sex differentiation: clinical and biological aspects. Frontiers in Endocrinology, vol. 20. Serono Symposia, pp. 135-152. 121 Swaab, D.F., Van Someren, E.J.W., Zhou, J.N., and Hofman, M.A. - Biological rhythms in the human life cycle and their relationship to functional changes in the suprachiasmatic nucleus. In: Buijs, R.M., Kalsbeek, A., Romijn, H.J., Pennartz, C.M.A. and Mirmiran, M. (eds.) Progress in Brain Research 111, Elsevier, Amsterdam, 1996, pp. 347-366. 122 Swaab, D.F. - Neuropeptides in hypothalamic pathology. In: B. Krisch and R. Mentlein (Eds.) The Peptidergic Neuron. Birkhauser Verlag, Basel, 1996, pp. 315-328. 1997 123 Hoogendijk, W.J.G., Van Someren, E.J.W., Mirmiran, M., Hofman, M.A., Lucassen, P.J., Zhou, J.-N., Swaab, D.F. (1996) Circadian rhythm-related behavioral disturbances and structural hypothalamic changes in Alzheimer s diseases. Int. Psychogeriatrics 8(suppl. 3): 245-252. 124 Lucassen, P.J., Tilders, F.J.H., Salehi, A., Swaab, D.F. - Neuropeptides vasopressin (AVP), oxytocin (OXT) and corticotropin-releasing hormone (CRH) in the human hypothalamus: activity changes in aging, Alzheimer s disease and depression. Aging, Clin.& Exp. Res. 9(suppl. to no.4): 48-50, 1997. 125 Swaab, D.F. - Neurobiology and neuropathology of the human hypothalamus. In: Bloom, F.E. and Hökfelt, T. (Eds.) Handbook of Chemical Neuroanatomy. The Primate Nervous System, Part I, vol. 13, pp. 39-137. 126 Swaab, D.F., Lucassen, P.J., Van de Nes, J.A.P., Ravid, R. and Salehi, A. - Reduced neuronal activity is one of the major hallmarks of Alzheimer's disease. In: B.T. Hyman, C. Duyckaerts, Y. Christen (Eds.) Connections, Cognition, and Alzheimer s Disease. Springer Verlag, Berlin, pp.83-104. 127 Swaab, D.F., Zhou, J.N., Fodor, M., Hofman, M.A. - Sexual differentiation of the human brain. In: Biomedical Reviews, vol. 7, pp. 17-32, The Bulgarian-American Center, Varna, Bulgaria, 1997 128 Swaab, D.F. - Hogere functies in lagere regionen: de opwaardering van de hypothalamus tot onderkamer in het huis van de menselijke geest. In: Van Everdingen, J.J.E. en Gerson, B.P.R. (eds.) Huis van de Geest, Boom/Belvédere, Amsterdam, pp. 37-46, 1997. 129 Swaab, D.F. - Prader-Willi syndrome and the hypothalamus. Acta Paediatr. Suppl. 423: 50-54, 1997. 130 Swaab, D.F., Zhou, J.N., Fodor, M. and Hofman, M.A. - Sexual differentiation of the human hypothalamus: differences according to sex, sexual orientation, and transsexuality. In: Ellis, L, Ebertz, L. (Eds.) Sexual orientation: toward biological understanding. Praeger, Westport, pp. 129-150. 82

131 Van Someren, E.J.W., Scherder, E.J.A., Lijzenga, C., Mirmiran, M., Swaab, D.F. - Stimulation of the circadian timing system is effective in the treatment of sleep-wake rhythm disturbances in aging and Alzheimer patients. In: Beersma, D.G.M., Arends, J.B.A.M., Van Bemmel, A.L., Hofman, W.F., Ruigt, G.S.F. (Eds.) Sleep-Wake Research in the Netherlands, vol. 8, Dutch Soc. for Sleep-Wake Research, pp. 99-103. 1998 132 Fliers, E., Wiersinga, W.M., Swaab, D.F. - Physiological and pathophysiological aspects of thyrotropinreleasing hormone (TRH) gene expression in the human hypothalamus. Thyroid 8: 921-928 133 Ravid, R., Swaab, D.F., Kamphorst, W., Salehi, A. - Brain Banking in Aging and Dementia Research - The Amsterdam Experience. In: Progress in Alzheimer s and Parkinson s Diseases. Fisher et al. (eds.), Plenum Publishing, pp. 277-285. 134 Salehi, A., Dubelaar, E.J.G., Ishunina, T., Swaab, D.F. - Neuronal activity and genetic background in Alzheimer s disease. In: Van Leeuwen, F.W., Salehi, A., Giger, R.J., Holtmaat, A.J.G.D., Verhaagen, J. (Eds.) Progress in Brain Res. 117: 71-89, Elsevier, Amsterdam. 135 Scherder, E.J.A., Van Someren, E.J.W., Swaab, D.F. - Transcutane electrische neuro stimulatie (TENS) verbetert het rust-activiteitritme van patiënten in een middenstadium van de ziekte van Alzheimer. In: Broese van Groenou, M.I., Deeg, D.J.H., Knipscheer, C.P.M., Ligthhart, G.J. (Eds.) VU-visies op veroudering, pp. 75-78. 136 Swaab, D.F., Lucassen, P.J., Salehi, A., Scherder, E.J.A., Van Someren, E.J.W., Verwer, R.W.H. - Reduced neuronal activity and reactivation in Alzheimer s disease. In: Verhaagen, J., Van Leeuwen, F.W., Salehi, A., Holtmaat, A.J.G.D. and Giger, R.J. (Eds.) Progress in Brain Research 117: 343-377, Elsevier, Amsterdam. 137 Swaab, D.F. - The human hypothalamo-neurohypophysial system in health and disease. In: Urban, I.J.A., Burbach, J.P.H. and De Wied, D. (Eds). Brain Vasopressin. Progress in Brain Research 119: 577-618. 138 Swaab, D.F. - Hersenontwikkeling, karakter en plasticiteit. In Psychoanalyse en Neurobiologie. Koerselman, G.F. en Van Tilburg, W. (Eds.), Stichting Psychoanalyse en Psychiatrie, 1998, pp. 11-20. 139 Swaab, D.F. - interview met René de Bok in Macht en Onmacht in de Geneeskunde. De toekomstvisie van Nederlandse topspecialisten. Uitgeverij Strengholt, 1998. 140 Uylings, H.B.M., Swaab, D.F., Hofman, M.A. - Hersenen in wording. In: Ontwikkeling van de hersenen. Cahiers Biowetenschappen en Maatschappij. Stichting Bio-Wetenschappen en Maatschappij, Rotterdam, 1998, pp. 5-15. 141 Van Someren, E.J.W., Scherder, E.J.A., Lijzenga, C., Mirmiran, M., Swaab, D.F. - Treatment of circadian rhythm disturbances in healthy and demented elderly. In: Touitou, Y (ed). Elsevier, Amsterdam, pp. 549-552. 1999 142 Salehi, A., Dubelaar, E.J.G., Ishunina, T.A. and Swaab, D.F. - Neuronal activity and genetic background in Alzheimer s disease. In: Iqbal, K., Swaab, D.F., Winblad, B. and Wisniewski, H.M. (Eds.), Alzheimer s Disease and Related Disorders. Etiology, Pathogenesis and Therapeutics..John Wiley & Sons, Ltd., pp. 487-492. 143 Scherder, E.J.A., Bouma, A., Van Someren, E.J.W. and Swaab, D.F. - Effects of transcutaneous electrical nerve stimulation (TENS) on mood and cognition in Alzheimer s disease. In: Iqbal, K., Swaab, D.F., Winblad, B. and Wisniewski, H.M. (Eds.), Alzheimer s Disease and Related Disorders. Etiology, Pathogenesis and Therapeutics. John Wiley & Sons, Ltd., pp. 763-769. 144 Swaab, D.F. - Biological rhythms in health and disease: the suprachiasmatic nucleus and the autonomous system. In: P.J. Vinken, G.W. Bruyn (Series Eds), O. Appenzeller (Volume Ed.), Handbook of Clinical Neurology, Elsevier, Amsterdam, Vol. 74, pp. 467-521. 145 Swaab, D.F., Lucassen, P.J., Salehi, A., Scherder, E.J.A., Van Someren, E.J.W. and Verwer, R.W.H. - Decreased neuronal activity and therapeutic strategies directed towards reactivation in Alzheimer s disease. In: Iqbal, K., Swaab, D.F., Winblad, B. and Wisniewski, H.M. (Eds.), Alzheimer s Disease and Related Disorders. Etiology, Pathogenesis and Therapeutics. John Wiley & Sons, Ltd., pp. 750-756. 146 Tilders, F.J.H., Schmidt, E.D., Hoogendijk, W.J.G., Swaab, D.F. - Delayed effects of stress and immune activation. In: Baillière s Clinical Endocrinology and Metabolism. Vol. 13, pp. 523-540. Harcourt Publishers Ltd. 147 Van Someren, E.J.W., Scherder, E.J.A. and Swaab, D.F. - Stimulation of the circadian timing system in healthy and demented elderly. In: Iqbal, K., Swaab, D.F., Winblad, B. and Wisniewski, H.M. (Eds.), Alzheimer s Disease and Related Disorders. Etiology, Pathogenesis and Therapeutics. John Wiley & 83

Sons, Ltd., pp. 771-779. 148 Van Someren, E.J.W., Scherder, E.J.A., Lijzenga, C., Swaab, D.F. - Het slaap-waakritme bij veroudering en dementie. In: Modern Sleep Medicine., Knuistingh Neven, A. (Ed.) Van Zuiden Communications, Alphen a/d Rijn. pp. 93-99. 2000 149 Swaab, D.F. - Hersenontwikkelingen. In: Zorgen na Morgen. Samengesteld door A.L.M. Lagro-Janssen. Van der Wees, Utrecht, p. 122. 150 Swaab, D.F., Fliers, E., Hoogendijk, W.J.G., Veltman, D.J., Zhou, J.N. - Interaction of prefrontal cortical and hypothalamic systems in the pathogenesis of depression. In: Uylings, H.B.M., Van Eden, C.G., De Bruin, J.P.C., Feenstra, M.P.G., Pennartz, C.M.A. (Eds.) Progress in Brain Research 126, pp. 376-396, Elsevier, Amsterdam. 151 Swaab, D.F. - Mensen maken altijd onderscheid tussen een omgevingsfactor en een biologische factor - het hele onderscheid tussen biologisch of sociaal is zo achterhaald!. In: K. Neuvel (ed.) Wee de Genen. Over de biologische fundamenten van menselijk gedrag. Meinema, Zoetermeer. 152 Van Someren, E.J.W., Riemersma, R.F., Swaab, D.F. - Chronobiologische mechanismen en behandelingen van nachtelijke onrust bij gezonde en demente ouderen. In: Ontwikkelingen in de Geriatrie. H.J.M. Cools, Lagaay, A.M., Roos, R.A.C., Verhoeff, J.B. (Eds.) LUMC 2000. 2001 153 Liu, R.-Y., Zhou, J.-N., Swaab, D.F. - Biological rhythm disorder: in aging and Alzheimer s disease. In: Neuroendocrinologie des démences. Hormones, plaisir, vieillissement. Michel, B.F. et al. (eds.). Solal, Marseille, 2001, pp. 11-30. 154 Swaab, D.F., Boer, K. - Functional teratogenic effects of chemicals on the developing brain. In: Fetal and Neonatal Neurology and Neurosurgery, third edition, Levene, M.I., Whittle, M.J., Chervenak, F.A., Punt, J., Bennett, M.J. (eds.). Churchill Livingstone, Edinburgh. 155 Swaab, D.F. - Hersenen, bewustzijn en geloof. Neurobiologische aspecten. In: Hersenen. Bewustzijn. Zicht op onszelf. P.M.F. Oomen, J.W.M. Osse, V.G.H.J. Kirkels (Eds.) Valkhof Pers, Nijmegen, pp. 79-95. 156 Swaab, D.F. and Huitinga, I. - The hypothalamus in multiple sclerosis. In: Pathology and clinical features of multiple sclerosis. Proceedings of the MS Forum in Athens, Greece. 157 Verhaagen, J., Swaab, D.F. - De toekomst van het onderzoek naar hersenletsel en herstel. In: Het Brein belicht: omgaan met de gevolgen van niet-aangeboren hersenletsel. Uitgeverij Lemma BV, Utrecht, pp. 65-75. 158 Swaab, D.F., Boer, K. - Functional teratogenic effects of chemicals on the developing brain. In: Fetal and Neonatal Neurology and Neurosurgery. Levene, M.I. et al. (eds.). Churchill Livingstone, London, 2001, pp.251-265. 2002 159 Hofman, M.A. and Swaab, D.F. - A brain for all seasons: cellular and molecular mechanisms of photoperiodic plasticity. In: Hofman, M.A., Boer, G.J., Holtmaat, A.J.G.D., Van Someren, E.J.W., Verhaagen, J., Swaab, D.F. Progress in Brain Research vol. 138. Plasticity in the Adult Brain: from genes to neurotherapy. Elsevier, Amsterdam, pp. 255-306. 160 Riemersma, R.F., Van Someren, E.J.W., Swaab, D.F. - 24-hour salivary melatonin rhythm in demented elderly. Sleep-wake research in the Netherlands. Vol. 13. Van Zuiden, Alphen a/d Rijn, pp. 88-90 161 Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A., Ishunina, T.A. - Sexual differentiation of the human hypothalamus. Proceedings Dallas Conference on Pediatric Gender Reassignment: a Critical Reappraisal. Adv. Exp. Med. Biol. 511: 75-100 162 Swaab, D.F. - Leo Isaac Swaab, vrouwenarts. In: Erflaters van de Geneeskunde. Kaandorp, C.J.E., Van Everdingen, J.J.E., Mooij, A. (Eds.) Belvédère/Medidact. Overveen/Alphen aan den Rijn, pp. 170-177. 163 Swaab, D.F. - Gender issues in brain structures and functions and their relevance for psychopathology. In: Part I: Basic Principles. Textbook Biological Psychiatry. D'Haenen, Den Boer, J.A., Willner, P. (Eds.), John Wiley & Sons, Ltd. pp. 189-209. 164 Swaab, D.F. and Hofman, M.A. - The fifteenth C.U. Ariëns Kappers Lecture. An Introduction. In: Hofman, M.A., Boer, G.J., Holtmaat, A.J.G.D., Van Someren, E.J.W., Verhaagen, J., Swaab, D.F. Progress in Brain Research vol. 138. Plasticity in the Adult Brain: from genes to neurotherapy. Elsevier, Amsterdam, pp. 397-399. 165 Swaab, D.F., Dubelaar, E.J.G., Hofman, M.A., Scherder, E.J.A., Van Someren, E.J.W., Verwer, R.W.H. 84

- Brain aging and Alzheimer s disease; use it or lose it. Progress in Brain Research vol. 138. Plasticity in the Adult Brain: from genes to neurotherapy Elsevier, Amsterdam, pp. 343-373. 166 Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A., Ishunina, T.A. - Sexual differentiation of the human hypothalamus. In: Zderic et al. (Eds.) Pediatric Gender Assignment: A Critical Reappraisal. Kluwer Academic/Plenum Publishers, Adv. Exp. Med. Biol. 511: 75-100. Discussion 100-105. 167 Van Someren, E.J.W., Riemersma, R.F., Swaab, D.F. - Functional plasticity of the circadian timing system in old age: light exposure. In: Hofman, M.A., Boer, G.J., Holtmaat, A.J.G.D., Van Someren, E.J.W., Verhaagen, J., Swaab, D.F. Progress in Brain Research vol. 138. Plasticity in the Adult Brain: from genes to neurotherapy. Elsevier, Amsterdam, pp. 205-231. 2003 168 Goldstone, A.P., Unmehopa, U.A., Swaab, D.F. - Hypothalamic neuropeptides in Prader-Willi syndrome: regulatory peptides (invited review). In: Eiholzer, U., l Allemand, D., Zipf, W.B. (eds.): Prader- Willi Syndrome as a Model for Obesity. Karger AG. Basel, pp. 31-43. 169 Goldstone, A.P., Unmehopa, U.A., Thomas, E.L., Brynes, A.E., Bell, J.D., Frost, G., Ghatei, M.A., Holland, A., Bloom, S.R., Swaab, D.F. - Hypothalamic neuropeptides and regulation of fat mass in Prader-Willi syndrome. In: Eiholzer, U., l Allemand, D., Zipf, W.B. (Eds.). Prader-Willi Syndrome as a Model for Obesity. International Symposium, Zurich, Basel, Karger, pp. 31-43. 170 Huitinga, I., Erkut, Z.A., Van Beurden, D., Swaab, D. - The hypothalamo-pituitary adrenal axis in multiple sclerosis. Ann. N.Y. Acad. Sci. 992: 118-128. 171 Raymann, R.J.E.M., Schneijdenberg, W., Drosopoulos, S., Den Haan, R., Van Braak, E., Van Krevelen, G., Collins, S., Vis, R., Swaab, D.F., Van Someren, E.J.W. - Effects of peripheral thermal stimulation on sleep onset latency and scores of subjective feelings associated with sleepiness. In: Bemmel, Beersma, Hofman, Ruigt and Vos (Eds.). Sleep-Wake Research in the Netherlands. Vol. 14, pp. 66-69. 172 Swaab, D.F., Hestiantoro, A., Wu, Y. - Neuroendocrinology of memory in Alzheimer s disease. In: Iqbal, K. and Winblad, B. (eds). Alzheimer s Disease and Related Disorders: Research Advances. Chapter 41, pp. 459-467. Published by: Ana Asian Intl. Acad. of Aging, Bucharest, Romania, 2003. 173 Swaab, D.F. - Reactivation of atrophic neurons in Alzheimer s disease. Neurol. Res. 25: 652-660, 2003. 2004 174 Hofman, M.A., Swaab, D.F. - Neuroplasticity in the human hypothalamus during aging: In: Mocchegiani, E. and Straub, R. (Eds.) The Neuroendocrine Immune Network in Aging, Elsevier, Amsterdam, pp. 105-121. 175 Riemersma, R.F., Mattheij, C.A.M., Swaab, D.F., Van Someren, E.J.W. - Melatonin rhythms and supplementation in old age. In: E. Mocchegioani (Ed.) Neuro-immune Biology, vol. 9. The Neuroendocrine immune network in ageing. Elsevier, Amsterdam, pp. 195-211. 176 Stoeckart, R., Swaab, D., Gijs, L., Slob, K. - Biologie van de seksualiteit; endocrinologische, anatomische en fysiologische aspecten. In: Gijs, L., Gianotten, W., Vanwesenbeeck, I., Weijenborg, P. (Eds.) Seksuologie. Bohn Stafleu Van Loghum, Houten, 2004, pp. 73-134. 177 Swaab, D.F., Kruijver, F.P.M., Hestiantoro, A. - Sex hormone receptors in the human hypothalamus in the different stages of human life. In: Genazzani, A.R. (Ed.) Hormone Replacement Therapy and the Brain. Controversial Issues in Climacteric Medicine Series, Parthenon Publishing Group, CRC Press, Boca Raton, pp. 44-56. 2005 178. Swaab, D.F. - The role of hypothalamus and endocrine system in sexuality. In; Hyde, J.S. (Ed.) Biological substrates of human sexuality, American Psychological Association, Washington DC, USA, pp. 21-74. 179. Swaab, D.F., Van Pelt, J., Hofman, M.A. - Introduction to the seventeenth C.U. Ariëns Kappers Lecture. Progress in Brain Research 147: 39-41. 180 Scherder, E.J.A., Swaab, D.F. - Pain in dementia. In: F. Cervero, T.S. Jensen (Eds.) Handbook of Clinical Neurology, vol. 81, Elsevier, Amsterdam 2006 181 Fliers, E., Alkemade, A., Wiersinga, W.M., Swaab, D.F. - Hypothalamic thyroid hormone feedback in health and disease. In: Kalsbeek, Fliers, Hofman, Swaab, Van Someren, Buijs (Eds.). Progress in Brain Research. Vol. 153: 189-207. 182 Hofman, M.A., Swaab, D.F. - The seventeenth C.U. Ariëns Kappers Lecture: an introduction. In: 85

Kalsbeek, Fliers, Hofman, Swaab, Van Someren, Buijs (Eds.). Progress in Brain Research. Vol. 153: 243-245. 183 Kalsbeek, A., Fliers, E., Hofman, M.A., Swaab, D.F., Van Someren, E.J.W., Buijs, R.M. Hypothalamic Integration of Energy Metabolism. In Kalsbeek, Fliers, Hofman, Swaab, Van Someren, Buijs (Eds.). Progress in Brain Research. Vol. 153: 184 Lucassen, P.J., Heine, V.M., Muller, M.B., Van der Beek, E., Wiegant, V.M., De Kloet, R., Joels, M., Fuchs, E., Swaab, D.F. and Czeh, B. Stress, depression and hippocampal apoptosis. In CNS & Nuerological Disorders Drug Targets 5, Bentham Science Publishers Ltd., pp. 531-546. 185 Scherder, E.J.A., Swaab, D.F. - Pain in dementia. In: F. Cervero, T.S. Jensen (Eds.) Handbook of Clinical Neurology. Vol. 81: 817-829. 186 Swaab, D.F. - Reactivation of metabolically impaired neurons in Alzheimer's disease. Proceedings of "Il International Congress on Neuroregeneration. Revista Brasileira de Neurologia, 99-112. 187 Swaab, D.F. - The human hypothalamus in metabolic and episodic disorders. In: Kalsbeek, Fliers, Hofman, Swaab, Van Someren, Buijs (Eds.). Progress in Brain Research. Vol. 153: 3-45. 2007 188 Swaab, D.F. - Ons karakter als aangeboren afwijking. In: W. Koops, B. Levering, M. de Winter (Eds.) Het kind als spiegel van de beschaving. Uitgeverij SWP, Amsterdam, pp. 45-61. 189 Swaab, D.F., De Ranitz, A.G.S. - Agressief en crimineel gedrag. In: Cath, D.C., Gijsbers van Wijk, C.M.T., Klumpers, U.M.H. (Eds.) Sekseverschillen in de psychiatrie. Een neurobiologische benadering. Van Gorcum 2007, pp. 208-229. 190 Swaab, D.F. - Seksuele differentiatie van het brein: bepalen je hersenen of je hetero of homo wordt? In: Jeroen Geurts: Over de Kop. Fascinerende vragen over het brein. Scriptum Psychologie, pp. 56-81. 191 Swaab, D.F. - Wij zijn onze hersenen: Over het brein en ons unieke karakter. In: Opvoeden, wat kun je? Carine Ex, Wereldbibliotheek, Amsterdam 2007, pp. 13-23. 2008 192 Swaab, D.F., Lucassen, P.J. - Neuroendocrinology of Eating Disorders. In: Encyclopedia of Neuroscience, Springer Science and Business Media, Heidelberg, Germany. 193 Swaab, D.F., Lucassen, P.J. - The Hypothalamo Neurohypophysial System. In: Encyclopedia of Neuroscience, Springer Science and Business Media, Heidelberg, Germany. 194 Swaab, D.F. - Verschil moet er zijn, maar in de hersenen mocht het niet. Woord vooraf. In: M. Delfos, Verschil Mag Er Zijn Waarom er mannen en vrouwen zijn. Uitgeverij Bert Bakker, Amsterdam, 2008, pp. 9-14. 2009 195 Kreier, F., Swaab, D.F. - History of neuroendocrinology: 'the spring of primitive existence'. In: Finger, S, Boller, F. Tyler, K.L., Eds. Handbook of Clinical Neurology, vol. 95 (3 rd series) History of Neurology, chapter 23, p. 335-360. 196 Swaab, D.F., Lucassen, P.J. - Neuroendocrinology of tumors. Encyclopedia of Neuroscience. Springer Science and Business Media, Heidelberg, Germany, 2645-2648. 197 Swaab, D.F., Lucassen, P.J. - Neuroendocrinology of eating disorders. Encyclopedia of Neuroscience. Springer Science and Business Media, Heidelberg, Germany. 2635-2637 198 Swaab, D.F., Lucassen, P.J. - Neuroendocrinology. Encyclopedia of Neuroscience. Springer Science and Business Media, Heidelberg, Germany, 2631-2635. 199 Bao, A-M., Lucassen, P.J., Swaab, D.F. - Neuroendocrinology of Psychiatric Disorders. Encyclopedia of Neuroscience. Springer Science and Business Media, Heidelberg, Germany, 2641-2645 200 Lucassen, P.J., Swaab, D.F. - Endocrine disorders of development and growth. Encyclopedia of Neuroscience. Springer Science and Business Media, Heidelberg, Germany 201 Lucassen, P.J., Swaab, D.F. - Hypothalamo-pituitary-adrenal axis, stress and depression. Encyclopedia of Neuroscience. Springer Science and Business Media, Heidelberg, Germany 202 Swaab, D.F., Lucassen, P.J. - Drinking disorders and osmoregulation. Encyclopedia of Neuroscience. Springer Science and Business Media, Heidelberg, Germany 203 Stoeckart, R., Swaab, D., Gijs, L., De Ronde, P., Slob, K. - Biologie van de seksualiteit; endocrinologische, anatomische en fysiologische aspecten. In: Gijs, L., Gianotten, W.L., Vanwesenbeeck, I., Weijenborg, P.T.M. (Eds). Seksuologie. Bohn Stafleu van Loghum, Houten, 2009 204 Verhaagen, J. and Swaab, D.F. - The eighteenth C.U. Ariëns Kappers lecture: an introduction. In: J. Verhaagen et al. (Eds). Progress in Brain Research, vol. 175, pp. 497-499. 205 Swaab, D.F., Verweij, W.T.P. - Neuro-Theology: Demasqué of Religions. In: Verhagen, P.J., Van 86

Praag, H.M., López-Ibor, J.L., Cox, J.L., Moussaioui, D. Religion and Psychiatry: Beyond Boundaries. John Wiley & Sons Ltd., 2009. 2010 205 Garcia-Falgueras, A., Swaab, D.F. - Sexual hormones and the brain: an essential alliance for sexual identity and sexual orientation. In: Loche, S., Cappa, M., Ghizzoni, L., Maghnie, M., Savage, M.O. (Eds.) Pediatric Neuroendocrinology, Endocr. Dev. Basel, Karger, vol 17, pp. 22-35. 206 Savic, I., Garcia-Falgueras, A., Swaab, D.F. - Sexual differentiation of the human brain in relation to gender identity and sexual orientation. In: Savic-Berglund, I. (Ed.). Progress in Brain Research, Elsevier, Amsterdam, vol. 186, 2010. 2011 207 Swaab, D.F. - Sexual differentiation of the human brain and male/female behaviour. In: Beets, G., Schippers, J. and te Velde, E. Eds. The Future of Motherhood in Western Societies: Late Fertility and Consquences, Springer, Dordrecht, pp. 33-47 208 Swaab, D.F. Foreword. In: ISAO collection on the occasion of the World Alzheimer Day, 21 September. 209 Swaab, D.F. Foreword. In: Doodeerlijk, A.A. Wouda. 210 Swaab, D.F. Levenslange gevolgen van je tijd in de baarmoeder. In: What s on your mind?! Alles over je hersenen. p. 9. Abbott and Volle Maan, 2011 211 Swaab, D.F. De neurobiologie van geheugen en intuïtie. In: Intuïtie in de Geneeskunde. Ed. F. Jonker & C. Tacke, pp. 9-11, De Tijdstroom, Utrecht. 212 Swaab, D.F. Mijn belangrijkste drijfveer is nieuwsgierigheid. In: Geloof in de Wetenschap. Ed. M. van Veelen, Buijten en Schipperheijn Motief, Amsterdam, pp 139-145 2012 213 Swaab, D.F., Bao, A-M., Garcia-Falgueras, A., Hofman, M.A., Ishunina, T.A. Sex differences in the forebrain. In: The Human Nervous System, 3 rd Edition, Elsevier Inc. 214 Swaab, D.F. Neurotheologie het demasqué van religies. In: P.J. Verhagen, H.J.G.M. van Megen, Handboek psychiatrie, religie en spiritualiteit. Uitgeverij De Tijdstroom, pp. 319-335. 215 V.D. Goncharuk and D.F. Swaab Essential hypertension as a hypothalamic disease. In: The Human Hypothalamus: Anatomy, Functions and Disorders. Nova Publishers. In press. 87

BOOKS EDITED 1974 1 Swaab, D.F. and J.P. Schadé - (Eds.) Integrative Hypothalamic Activity. Progress in Brain Research, Vol. 41. Elsevier/North-Holland Biomedical Press, Amsterdam, 1974. 1975 2 Querido, A. and D.F. Swaab - (Eds.) Brain Development and Thyroid Deficiency. North-Holland Publishing Comp., Amsterdam-New York, 1975. 1976 3 Corner, M.A. and D.F. Swaab - (Eds.) Perspectives in Brain Research. Progress in Brain Research, Vol. 45. Elsevier/North-Holland Biomedical Press, Amsterdam, 1976. 1977 4 Tilders, F.J.H., D.F. Swaab and Tj.B. Van Wimersma Greidanus - (Eds.) Melanocyte Stimulating Hormone: Control, Chemistry and Effects. Karger, Basel, 1977. 1986 5 Swaab, D.F., E. Fliers, M. Mirmiran, W.A. Van Gool and F. Van Haaren - (Eds.) Aging of the Brain and Alzheimer's Disease. Progress in Brain Research. Vol.70, Elsevier Biomedical Press, Amsterdam, 1986. 1988 6 Boer, G.J., M.G.P. Feenstra, M. Mirmiran, D.F. Swaab and F. Van Haaren (Eds.) - Biochemical Basis of Functionional Neuroteratology: permanent effects of chemicals on the developing brain. Progr. Brain Res., Vol.73, Elsevier Biomed. Press, Amsterdam, 1988. 1992 7 Swaab, D.F., M.A. Hofman, M. Mirmiran, R. Ravid and F.W. Van Leeuwen (Eds.) - The Human Hypothalamus in Health and Disease. Progress in Brain Research 93, Elsevier, Amsterdam. 1999 8 Iqbal, K., Swaab, D.F., Winblad, B., Wisniewski, H.M. (Eds.) - Alzheimer s disease and related disorders. Etiology, pathogenesis and therapeutics. John Wiley and Sons, Ltd., Chicester. 2002 9 Hofman, M.A., Boer, G.J., Holtmaat, A.J.G.D., Van Someren, E.J.W., Verhaagen, J., Swaab, D.F. - Plasticity in the adult brain: from genes to neurotherapy. Progress in Brain Research, vol. 138, Elsevier, Amsterdam 2006 10 Aminoff, M.J., Boller, F., Swaab, D.F. - Pain. Handbook of Clinical Neurology, vol. 81, 900 pp. Elsevier, Edinburgh 11 Kalsbeek, A., Fliers, E., Hofman, M.A., Swaab, D.F., Van Someren, E.J.W., Buijs, R.M. (Eds.) - Hypothalamic Integration of Energy Metabolism. Progress in Brain Research, vol. 153, 414 pp., Elsevier, Amsterdam 12 Aminoff, M.J., Boller, F., Swaab, D.F. - Motor Neuron Disorders and Related Diseases, vol. 82, Elsevier, Edinburgh 2007 13 Aminoff, M.J., Boller, F., Swaab, D.F. - Parkinson's Disease and Related Disorders, Part I, vol. 83, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh 14 Aminoff, M.J., Boller, F., Swaab, D.F. - Parkinson's Disease and Related Disorders, Part II, vol. 84, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh 15 Aminoff, M.J., Boller, F., Swaab, D.F. - HIV/AIDS and the nervous system. vol. 85, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh 16 Aminoff, M.J., Boller, F., Swaab, D.F. - Myopathies, vol. 86, 3 rd series Handbook of Clinical Neurology, 88

Elsevier, Edinburgh 17 Aminoff, M.J., Boller, F., Swaab, D.F. - Malformations of the Nervous System, vol. 87, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh 18 Aminoff, M.J., Boller, F., Swaab, D.F. - Neuropsychology and behavioral neurology. Vol. 88, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh 2008 19 Aminoff, M.J., Boller, F., Swaab, D.F. - Dementias. Vol. 89, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh 20 Aminoff, M.J., Boller, F., Swaab, D.F. - Disorders of Consciousness, Vol. 90, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh. 21 Aminoff, M.J., Boller, F., Swaab, D.F. - Neuromuscular Junction Disorders. Vol. 91, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh. 2009 22 Aminoff, M.J., Boller, F., Swaab, D.F. - Stroke. Part I: Basic and Epidemiological Aspects. Vol. 92, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh. 23 Aminoff, M.J., Boller, F., Swaab, D.F. - Stroke. Part II: Clinical Manifestations and Pathogenesis. Vol. 93, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh. 24 Aminoff, M.J., Boller, F., Swaab, D.F. - Stroke. Part III: Investigation and Management. Vol. 94, 3 rd series Handbook of Clinical Neurology, Elsevier, Edinburgh. 24 Swaab, D.F. (Advisor) - Textbook of Veterinary Anatomy. Dyce, K.M., Sack, W.O., Wensing, C.J.G. (Eds), Saunders Elsevier, 2009 2010 25 Aminoff, M.J., Boller, F., Swaab, D.F. - History of Neurology, vol. 95. Elsevier Edinburgh. 26 Aminoff, M.J., Boller, F., Swaab, D.F. - Handbook of Clinical Neurology, vol. 96, Bacterial Infections of the Central Nervous System, Elsevier Edinburgh. 27 Aminoff, M.J., Boller, F., Swaab, D.F. - Handbook of Clinical Neurology, vol. 97, Headache. Elsevier Edinburgh. 2011 28 Aminoff, M.J., Boller, F., Swaab, D.F. - Handbook of Clinical Neurology, vol. 100, Hyperkinetic Movement Disorders, Elsevier Edinburgh. 29 Aminoff, M.J., Boller, F., Swaab, D.F. - Handbook of Clinical Neurology, vol. 101, Muscular Dystrophies, Elsevier Edinburgh. 30 Aminoff, M.J., Boller, F., Swaab, D.F. - Handbook of Clinical Neurology, vol. 102, Neuroophthalmology, Elsevier Edinburgh. 31 Aminoff, M.J., Boller, F., Swaab, D.F. Handbook of Clinical Neurology, vol. 104, Neuro-Oncology, Part I, Elsevier, Edinburgh. 32 Aminoff, M.J., Boller, F., Swaab, D.F. Handbook of Clinical Neurology, vol. 105, Neuro-Oncology, Part II, Elsevier, Edinburgh 89

REPORTS and COLUMNS 1976 1 Swaab, D.F. - (Ed.) Netherlands Central Institute for Brain Research, Amsterdam. Progress Report 1975. Verhandelingen der Koninklijke Nederlandse Akademie van Wetenschappen, Afd. Natuurkunde, Tweede Reeks, Deel 67, 1976. 1977 2 Swaab, D.F. - The Netherlands Institute for Brain Research. NUFFIC Bull. 21(2), 13-20, 1977. 3 Swaab, D.F. - (Ed.) Netherlands Central Institute for Brain Research, Amsterdam. Progress Report 1976. Verhandelingen der Koninklijke Nederlandse Akademie van Wetenschappen, Afd. Natuurkunde, Tweede Reeks, Deel 68, 1977. 4 Swaab, D.F. - Algemene inleiding Neuroendocrinologie. PAO-cursus `Neuroendocrinologie', Nederlands Instituut voor Hersenonderzoek en Biologische Raad van de KNAW, 1977. 1978 5 Swaab, D.F. - Netherlands Institute for Brain Research. Progress Report 1977. Verhandelingen der Koninklijke Nederlandse Akademie van Wetenschappen, Afd. Natuurkunde, Tweede Reeks, Deel 71, 1978. 1979 6 Swaab, D.F. - Netherlands Institute for Brain Research. Progress Report 1978. Verhandelingen der Koninklijke Nederlandse Akademie van Wetenschappen, Afd. Natuurkunde, Tweede Reeks, Deel 73, 1979. 1980 7 Swaab, D.F. - Netherlands Institute for Brain Research. Progress Report Verhandelingen der Koninklijke Nederlandse Akademie van Wetenschappen, Afd. Natuurkunde, Tweede Reeks, Deel 75, 1980. 1981 8 Swaab, D.F. (Ed.) - Nederlandse Vereniging voor Endocrinologie, Verenigingsverslag vergadering 18 oktober 1980, Utrecht. Ned. T. Geneesk. 125, 605-608, 1981. 9 Swaab, D.F. (Ed.) - Nederlandse Vereniging voor Endocrinologie, Verenigingsverslag vergadering 21 februari 1981, Utrecht. Ned. T. Geneesk. 125, 1142-1144, 1981. 10 Swaab, D.F. - Netherlands Institute for Brain Research. Progress Report 1980. Verhandelingen der Koninklijke Nederlandse Akademie van Wetenschappen, Afd. Natuurkunde, Tweede Reeks, Deel 77, 1981. 1982 11 Swaab, D.F., M.A. Corner and W. Chen-Pelt - Netherlands Institute for Brain Research. Progress Report 1981. Verhandelingen der Koninklijke Nederlandse Akademie van Wetenschappen, Afd. Natuurkunde, Tweede Reeks, Deel 79, 1982. 1983 12 Fliers, E., A. Lisei and D.F. Swaab - Dementia. Some current concepts and research in The Netherlands. (op verzoek van het Ned. Inst. v. Gerontologie) Ned. Inst. v. Hersenonderzoek, Amsterdam, pp. 1-47, 1983. 13 Fliers, E., A. Lisei and D.F. Swaab - Dementie: recente inzichten en onderzoek in Nederland; Samenvatting van een reviewstudie in opdracht van het Ned. Inst. v. Gerontologie, Stichting Studentenpers, Nijmegen, pp. 1-27, 1983. 14 Swaab, D.F. - Resultaten en conclusies van de SOOM-Workshop,`Dementie onderzoek', t.b.v. de Stichting Onderzoek op het terrein van de Ouder wordende Mens (SOOM), October 1983, 1-7, 1983. 15 Van de Poll, N.E., D.F. Swaab and W. Chen-Pelt - Progress Report 1982 of the Netherlands Institute for Brain Research. Reprinted from: `Institutes of the Royal Netherlands Academy of Arts and Sciences, Progress Report 1982'. Verh. KNAW, Afd. Nat., 2e reeks, deel 81, pp.1-63, 1983. 1985 16 Chen-Pelt, W., P.J. Van Nieuwkoop and D.F. Swaab - Progress Report 1985 of the Netherlands 90

Institute for Brain Research. Koninklijke Nederlandse Akademie van Wetenschappen, 1985. 17 Swaab, D.F., (co-author of) Advies inzake teratogeniteit van chemische stoffen. Gezondheidsraad, Den Haag, 11 maart 1985. 18 Swaab, D.F., G.J. Boer en H.B.M. Uylings - Neurowetenschappen. In: Innovatieve Ontwikkelingen in de Neurowetenschappen, Jaarboek Gezondheidsraad 1985, 134-139. 1986 19 Swaab, D.F. (co-author of) - Report on the evaluation of the teratogenicity of chemical substances. Health Council of the Netherlands, 129 pp., 1986. 1987 20 Swaab, D.F. (co-author of) - Report on Clinical, pathological and experimental opportunities for collaborative research on ageing of the brain and dementia in the EEG countries and Switzerland, EURAGE, Rijswijk, 1987. 21 Swaab, D.F. (co-author of) - Report on Dementie en de Ziekte van Alzheimer, MEDIGON, 1987. 22 Swaab, D.F., E. Fliers and E. Goudsmit - Onderzoek naar vasopressineneuronen tijdens de veroudering en bij Alzheimer-patiënten. ZWO-jaarboek 1986, 225-230, 1987. 23 Swaab, D.F., E. Fliers and W.A. Van Gool - Multidisciplinair onderzoek naar circadiane ritme veranderingen tijdens veroudering en bij de ziekte van Alzheimer; noodzaak van infrastructurele voorzieningen als een hersenbank. In: SOOM Werkdocumenten nr. 14, `Kennis over ouder', E.G.J. Küper-Carriere (Ed.), pp.13-21, 1987. 24 Swaab, D.F. and J. Jolles - Dementie en de ziekte van Alzheimer. In: MEDIGON Beleidsnota 1987-1991, pp.549, 1987. 1989 25 Swaab, D.F. - Veel informatie maar geen genezing van MS. NRC Handelsblad, 14 March 1989. 26 Swaab, D.F. - Standpunt: Schizofrenie. In: Het Parool, 11 Nov. 1989. 27 Swaab, D.F., D. Knook and A. Hofman - Standpunt: Hersenonderzoek naar dementie en de ziekte van Alzheimer - Waar blijft Nederland? In: Het Parool, 16 september 1989. 1990 28 Swaab, D.F. - Standpunt: Alzheimer. In: Het Parool, 6 January 1990, 17. 29 Swaab, D.F. - Osteopathie en MS. In: Op Zoek 35, April 1990. 30 Swaab, D.F. - Standpunt: Geboorte. In: Het Parool, 17 March 1990, 17. 31 Swaab, D.F. - Standpunt: Vruchten. In: Het Parool, 5 May 1990. 32 Swaab, D.F. - Standpunt: Vervuiling. In: Het Parool, 23 June 1990. 33 Swaab, D.F. - Standpunt: Spons. In: Het Parool, 25 August 1990. 34 Swaab, D.F. - Standpunt: Mosselen. In: Het Parool, 20 October 1990. 35 Swaab, D.F. - Myelinetransplantatie en MS. Op Zoek 27 (Oct./Nov 1990), 110-111. 36 Swaab, D.F. - Standpunt: Querido. In: Het Parool, 15 December 1990. 1991 37 Swaab, D.F. - Dementia (in Dutch) In: Kijken in Hersenen, N. Model and J.M. van Ree (Eds.), Kok Kampen, pp. 63-69. 38 Swaab, D.F. - Dementie. In: H. Mochel and J.M. van Ree (Eds.), Kijken in Hersenen, Kok, Kampen, pp. 63-69, 1991. 39 Swaab, D.F. - Standpunt: Melatonine, Het Parool, 16 January 1991. 40 Swaab, D.F. - Standpunt: Parkinson, Het Parool, 13 April 1991. 41 Swaab, D.F. - Standpunt: Ziel, Het Parool, 1 June 1991. 42 Swaab, D.F. - Mysterie ALS is nog steeds onopgelost (article on Amyotrophic Lateral Sclerosis), Het Parool, 31 augustus 1991. 43 Swaab, D.F. Boksen. Het Parool, 2 november 1991. 1992 44 Ravid, R., D.F. Swaab, J. Steinmetz and F. Veltmeijer (Eds.) - Progress Report of the Netherlands Brain Bank. 45 Ravid, R., D.F. Swaab, F. Veltmeijer (Eds.) - Jaarverslag Nederlandse Hersenbank, Amsterdam. 46 Swaab, D.F. - De ziekte van Alzheimer. Column voor het neurobiologisch symposium: Het Brein in Stukken, 11 November 1992. 91

47 Swaab, D.F. - Alles staat bij de geboorte al vast. HN Magazine 48, p. 5-7. 1993 48 Swaab, D.F., O. Pach and W.T.P. Verweij (Eds.) - Progress Report Netherlands Institute for Brain Research 1992. 49 Swaab, D.F. - De Nederlandse Hersenbank: op zoek naar gezond verstand. Hersenpanne. Hersenstichting Nederland. Den Haag, p. 7. 50 Swaab, D.F. - Hersenen en Geest. Leidse Biologen Almanak, p. 227-230. 1996 51 Swaab, D.F. - Anorexia nervosa en bulimia nervosa: ziekten van de hypothalamus? CNS Review 1: 14-15, 1996 52 Swaab, D.F. - Tien jaar Nederlandse Hersenbank. Mediator 7: 6-8, 1996. 53 Swaab, D.F. - Neuropornografie. CNS Review 1, 11, 1996 1997 54 Swaab, D.F. - Wij zijn onze hersenen. CNS Review 2, 13, 1997 55 Swaab, D.F. - Little Wrong. CNS Review 2, 15, 1997 56 Swaab, D.F. - De onmaakbaarheid van sexe en sex. CNS Review 2, 12-13. 57 Swaab, D.F. - De biologische basis van Genesis: ritmen van een week. CNS Review 3, 58 Swaab, D.F. - Granuloompjes. In Sarcoïdose Nieuws, 16e jaargang, no. 4, december 1997, pp. 8-9. 1998 59 Swaab, D.F. - Granuloompjes II. In Sarcoïdose Nieuws, 17e jaargang, no. 1, februari 1998, p. 12. 60 Swaab, D.F. - Granuloompjes III. In Sarcoïdose Nieuws, 17e jaargang, no. 2, juli 1998, p.21. 61 Ravid, R., Swaab, D.F., Van den Berg, M. (Eds.) - Nederlande Hersenbank: Jaarverslag 1996-1997. 62 Ravid, R., Swaab, D.F., Van den Berg, M. (Eds.) - Nederlande Hersenbank: Progress Report 1996-1997. 63 Swaab, D.F. - Granuloompjes IV. In Sarcoïdose Nieuws, 17e jaargang, no. 3, p.8. 64 Swaab, D.F. - Hersenblessure? Medisch Contact 40: 1269, 1998 65 Swaab, D.F. - Granuloompjes V. In Sarcoïdose Nieuws, 17e jaargang, 5-6, 1998. 1999 66 Swaab, D.F. - Granuloompjes VI. In Sarcoïdose Nieuws, 18e jaargang, #2, p. 6-7. 67 Goldstone, A.P. and Swaab, D.F. - What causes the increased appetite in Prader-Willi syndrome? Pickwick Papers, vol. 11: 12-13, 1999. 68 Goldstone, A.P. and Swaab, D.F. - What causes the increased appetite in Prader-Willi syndrome? Wavelength 20-22 68 Swaab, D.F. - Hersenontwikkelingen. Koninklijke Nederlandsche Maatschappij tot Bevordering der Geneeskunst, Jubileumspecial Medisch Contact, p. 20, 13 nov. 1999 69 Swaab, D.F. - Granuloompjes VII. In Sarcoïdose Nieuws, 18e jaargang, #3, p. 6-7. 70 Swaab, D.F. - boekbespreking van Handbook of the Aging Brain voor het Tijdschrift voor Gerontologie en Geriatrie 30, p. 204. 71 Swaab, D.F. - boekbespreking van Ouderdom Bestaat Niet voor het Tijdschrift voor Gerontologie en Geriatrie 30, p. 211. 72 Swaab, D.F. - Granuloompjes VIII. In Sarcoïdose Nieuws, 18e jaargang, #4, p. 8-9. 73 Swaab, D.F. - Eight suggestions for the development of Alzheimer research in China. Newsletter of Senile Dementia 1, China Association of Alzheimer s Disease Scientists, Xuanwu Hospital, Capital University of Medical Sciences: 10-11. 74 Swaab, D.F. - Mensen maken altijd onderscheid tussen een omgevingsfactor en een biologische factor - het hele onderscheid tussen biologisch of sociaal is zo achterhaald! In: Wee de Genen, K. Neuvel (Ed.) Uitgeverij Meinema, Zoetermeer. pp. 157-168 2000 75 Swaab, D.F. - Reactie op stelling Binnen 10 jaar zal een medicijn de ziekte van Alzheimer bij de wortel aanpakken. Alzheimer Magazine. 76 Swaab, D.F. - Granuloompjes IX. Sarcoïdose Nieuws, 19e jaargang, nr. 3, 10-11. 77 Van Someren, E.J.W., Riemersma, R.F., Swaab, D.F. - Licht en melatonine in de behandeling van nachtelijke onrust. Alzheimer Magazine 1, pp. 22-24. 92

78 Swaab, D.F. - Wij zijn onze hersenen. In: Trouw. Rubriek Letter en Geest, p. 47, 30 september 2000. 79 Swaab, D.F. - Granuloompjes X. Sarcoïdose Nieuws, 19e jaargang, nr. 4, p. 11. 80 Swaab, D.F. - Alzheimer onderzoek: het begin van een beter einde. David de Wied-lecture 2000. Stichting David de Wied-lezing, Universiteit Utrecht en CenE Bankiers NV, Utrecht, 14 april 2000. 2001 81 Swaab, D.F. - Boekbespreking van Alzheimer's disease. A compendium of current theories. Annals of the New York Academy of Sciences, vol. 924, USA. Ed. by Zaven S. Khachaturian and M.-Marsel Mesulam. In: Ned. Tijdschrift voor Gerontologie, jaargang 32, p. 136. 82 Swaab, D.F. - Granuloompjes XI. Sarcoidose Nieuws, 20ste jaargang no. 2, 10. 83 Swaab, D.F. - Portret van Prof. dr. David de Wied. In: Dertien in een dozijn. Wetenschappelijke uitgeverij Bunge, Utrecht (offered). 84 Swaab, D.F. - Wij zijn onze hersenen. Fysioscoop, 27ste jaargang, nr. 4, p. 9. 85 Gill, K., Tibben, A., Swaab, D.F. - Als het leven niets meer biedt. (offered) 86 Swaab, D.F. - Granuloompjes XII. Sarcoidose Nieuws, 20ste jaargang no. 4, p.8. 87 Swaab, D.F. - Criminele hersenen. In: Natuur en Techniek, 69e jaargang, 2001. 88 Swaab, D.F. - Boekbespreking van: Alzheimer s Disease and Related Disorders. Annual 2001, Gauthier and Cummings (Eds). Martin Dunitz Ltd. London, 216 pp. in Tijdschrift voor Gerontologie 32, p. 283, 2001. 2002 89 Swaab, D.F. - Boekbespreking van Valk, J., Barkhof, F., Scheltens, P. - Magnetic resonance in dementia. Springer, Heidelberg, Germany, 2002, 353 p. in Tijdschrift voor Gerontologie en Geriatrie 33, p. 92, 2002. 90 Swaab, D.F. - Boekbespreking van Szesko, P.R., Strous, R.D., Goldman, R.S., Ahstari, M., Knuth, K.H., Lieberman, J.A., Bilder, R.M. - Neuropsychological correlates of hippocampal volumes in patients experiencing a first episode of schizophrenia in Nederlands Tijdschrift voor Geneeskunde, 146: 871-872, 2002. 91 Swaab, D.F. - portret David de Wied. Academische Boekengids 31, 2002 92 Swaab, D.F. - Granuloompjes XIII. Sarcoïdose Nieuws, 21ste jaargang, nr. 2, p. 7-8 93 Swaab, D.F. - Placebo heeft een meetbaar effect op de hersenfunctie bij depressie. Ned. Tijdschrift v. Geneeskunde 146: 1709. 94 Swaab, D.F. - Meer post-mortemhersenonderzoek van schizofreniepatiënten wenselijk. Ned. Tijdschrift v. Geneeskunde 146: 871. 95 Swaab, D.F. - Dementie. Advies van een commissie van de Gezondheidsraad aan de Minister van Volksgezondheid, Welzijn en Sport, Den Haag: Gezondheidsraad, 2002, publicatienummer 2002/04. 96 Swaab, D.F. - Dementia. Advice by a committee of the Health Council of the Netherlands to the Minister of Health, Welfare and Sport, The Hague. Health Council of the Netherlands 2002, nr. 2002/04E. 97 Swaab, D.F. - Zonder Fosfor Geen Gedachten. AMC Magazine, december 2002, p. 22. 98 Swaab, D.F. - Granuloompjes XIV. Sarcoïdose Nieuws 3, 21ste jaargang, 2002, p. 10. 2003 99 Swaab, D.F. - Granuloompjes XV. Sarcoïdose Nieuws 1, 22ste jaargang, 2003, nr. 1, p. 16-17 100 Swaab, D.F. - Granuloompjes XVI. Sarcoïdose Nieuws 2, 22ste jaargang, 2003, nr. 2, p. 15. 101 Swaab, D.F. - Is er Leven na de (hersen)dood? Thomas More Lecture, Maastricht, p. 49-50 102 Swaab, D.F. - Evolutionair gezien zijn we weinig meer dan wegwerpartikelen. In: Visser, H. (Ed.) Leven zonder God. Elf interviews over ongeloof. LJ Veen. pp.139. 103 Swaab, D.F. - Granuloompjes XVII. Sarcoïdose Nieuws 3, 22ste jaargang, nr. 3, p. 12-13. 104 Swaab D.F. - Position paper on HRT in climacteric and aging brain. Member of Scientific Panel, edited by Genazzani, A.R., Gambacciani, M., Simoncini, T., Schneider, H.P.G. (eds.) Controversial Issues in Climacteric Medicine series. Climacteric 6: 188-203. 105 Swaab, D.F. - Granuloompjes XVIII ( Bidden ). Sarcoïdose Nieuws. 22ste jaargang, no. 4, p. 16. 106 Swaab, D.F. - Geheugen in een ouder brein. Alzheimer Magazine, jaargang 6. nr. 4, p. 4-5. 107 Swaab, D.F. - Neurons in the human postmortem brain are still very much alive. Brain Res. vol. 1000. 107 Van Someren, E.J.W., Riemersma, R., Raymann, R., Swaab, D.F. - Het effect van licht en temperatuur op verstoord slaap-waakritme bij ouderen. Psychopraxis jaargang 5, nr. 2, p. 48-50. 93

2004 108 Swaab, D.F. - Granuloompjes XIX: Zenuwen. Sarcoïdose Nieuws. 23ste jaargang, no. 2, p. 14. 109 Swaab, D.F. - Granuloompjes XX: de zorg van mijn longarts Carel Roos. Sarcoïdose Nieuws. Jaargang 23, no. 3, p. 18-19. 110 Besser, M., Carr, S., Cohen-Kettenis, P., Connolly, P., De Sutter, P., Diamond, M., Di Ceglie, D., Higashi, Y., Kruijver, F., Martin, J., Playdon, Z-J., Ralph, D., Reed, T., Reid, R., Reiner, W., Swaab, D., Terry, T., Wilson, P., Wylie, K. (BBC Trans Group). Atypical gender development. Gires, King's Fund, april 2004, pp. 1-19. In press (2006) Int. J. Transsexualism 2005 111 Swaab, D.F. - Granuloompjes XXI: Bezuinig nu op onderzoek en bezuur het later. Jaargang 23, no. 4, p. 22-23. 112 Swaab, D.F. - Granuloompjes XXII: Sarcoïdose door stamceltransplantatie. Jaargang 24, no 1, p. 26. 113 Swaab, D.F. - two papers for 25 years of MS Research, patient magazine MenSen. 114 Swaab, D.F. - Zijn moeders echt slimmer? Bespreking van Moederbrein - Hoe moederschap je slimmer maakt, van Katherine Ellison. Opzij, p. 20, september 2005 115 Swaab, D.F. - Granuloompje XXIII: Donor? 116 Swaab, D.F. - Granuloompjes XXIV: Tatoeages en piercings. Sarcoïdose Nieuws, jaargang 24, nr. 4, december 2005, p. 18 117 Swaab, D.F. - Wij zijn onze hersenen. Academy Magazine, winter 2005/2006, pp. 16-29 2006 118 Swaab, D.F. - Granuloompjes XXV. Lang leven en Chinese kruiden. Sarcoïdose Nieuws, jaargang 25, p. 25-28. 119 Swaab, D.F. - De hersenen; het placebo-effect. Het onbewuste zelfhelende vermogen. Lentekriebels. Hersenen (???) pp. 22-24. 120 Swaab, D.F. - Hans Ariëns Kappers. Levensbericht door D.F. Swaab. In: Levensberichten en herdenkingen 2006, Koninklijke Nederlandse Akademie van Wetenschappen. 121 Swaab, D.F. - Wij zijn onze hersenen. In: Proviand, juni 2006, p. 5 2007 122 Swaab, D.F. - Nawoord bij Het biologische misverstand, D. Mesland (Ed.). 123 Swaab, D.F. - De analytische psychiatrie in zicht. In: Health Management Forum. Tijdschrift voor toekomstverkenning, strategieontwikkeling en innovatie. maart 2007-07-30 2008 124 Swaab, D.F. - Swaab over hersenen. Wij zijn ons brein. NRC Handelsblad weekendeditie, 22/23 maart. 125 Swaab, D.F. - Swaab over hersenen. Bijna-dood kan niet. NRC Handelsblad weekendeditie, 29/30 maart. 126 Swaab, D.F. - Swaab over hersenen. De week is in de urine. NRC Handelsblad weekendeditie, 5/6 april 127 Swaab, D.F. - De onbetrouwbare bijbel. Boekbespreking van Omhoog Kijken in Platland. Over geloven in de wetenschap, door Kees Dekker. De Academische Boekengids 66, januari 2008, p. 35. 128 Swaab, D.F. - Swaab over hersenen. Effectieve placebo's. NRC Handelsblad weekendeditie 12/13 april 2008 129 Swaab, D.F. - Swaab over hersenen. Zwarte Jan. NRC Handelsblad weekendeditie 19/20 april 2008 130 Swaab, D.F. - Swaab over hersenen. Schade na de liefde. NRC Handelsblad weekendeditie 26/27 april 2008 131 Swaab, D.F. - Swaab over hersenen. Het verliefde brein. NRC Handelsblad weekendeditie 3/4 mei 2008 132 Swaab, D.F. - Swaab over hersenen. Agressief de buik uit. NRC Handelsblad weekendeditie 10/11 mei 2008 133 Swaab, D.F. - Swaab over hersenen. Onreine mosselen. NRC Handelsblad weekendeditie 17/18 mei 2008 134 Swaab, D.F. - Swaab over hersenen. Cursus Uitburgering. NRC Handelsblad weekendeditie 24/25 mei 2008 135 Swaab, D.F. - Swaab over hersenen. Gevraagd: hersenen. NRC Handelsblad weekendeditie 7/8 juni 2008 136 Swaab, D.F. - Swaab over hersenen. Oorlog in de Zomer. NRC Handelsblad weekendeditie 14/15 juni 2008 94

137 Swaab, D.F. - Swaab over hersenen. He, ho of bi. NRC Handelsblad weekendeditie 21/22 juni 2008. 138 Swaab, D.F. - Swaab over hersenen. Agressie. NRC Handelsblad weekendeditie 28/29 juni 2008. 139 Swaab, D.F. - Swaab over hersenen. Geluk bij Ongeluk. NRC Handelsblad weekendeditie 5/6 juli 2008 140 Swaab, D.F. - Swaab over hersenen. Geneesgebed. NRC Handelsblad weekendeditie 11/12 juli 2008 141 Swaab, D.F. - Swaab over hersenen. Man/vrouw. NRC Handelsblad weekendeditie, 19/20 juli 2008 142 Swaab, D.F. - Swaab over hersenen. Groepsstraf. NRC Handelsblad weekendeditie 26/27 juli 2008 143 Swaab, D.F. - Swaab over hersenen. Freuds gelijk. NRC Handelsblad weekendeditie 2/3 augustus 2008 144 Swaab, D.F. - Swaab over hersenen. Olympische seksen. NRC Handelsblad weekendeditie 9/10 augustus 2008 145 Swaab, D.F. - Swaab over hersenen. Neuroporno. NRC Handelsblad weekendeditie 16/17 augustus 2008 146 Swaab, D.F. - Swaab over hersenen. Hersenstimulatie. NRC Handelsblad weekendeditie, 23/24 augustus 2008 147 Swaab, D.F. - Swaab over hersenen. De 21 gram. NRC Handelsblad weekendeditie 30/31 augustus 2008 148 Swaab, D.F. - Swaab over hersenen. Baren doe je samen. NRC Handelsblad weekendeditie 6/7 september 2008 149 Swaab, D.F. - Swaab over hersenen. Prothese in het brein. NRC Handelsblad weekendeditie 13/14 september 2008 150 Swaab, D.F. - Swaab over hersenen. Blinde ouderdom. NRC Handelsblad weekendeditie 20/21 september 2008 151 Swaab, D.F. - Swaab over hersenen. Denken en geloven. NRC Handelsblad weekendeditie 27/28 september 2008 152 Swaab, D.F. - Swaab over hersenen. Geen keus. NRC Handelsblad weekendeditie 4/5 oktober 2008 153 Swaab, D.F. - PWS Research in mice and human brain. In: Wavelength (newsletter for parents and professionals - International Prader-Willi Syndrome Organisation), vol. 2, pp. 22-23, July 2008 154 Swaab, D.F. - Swaab over hersenen. Zelf je arm afzagen. NRC Handelsblad weekendeditie 11/12 oktober 2008 155 Swaab, D.F. - Swaab over hersenen. Half leven. NRC Handelsblad weekendeditie 18/19 oktober 2008 156 Swaab, D.F. - Swaab over hersenen. Aangeboren. NRC Handelsblad weekendeditie 25/26 oktober 2008 157 Swaab, D.F. - Verschil moet er zijn, maar in de hersenen mocht het niet. In: Martine F. Delfos. Verschil mag er zijn. Uitgeverij Bert Bakker, Amsterdam. 158 Swaab, D.F. - Swaab over hersenen. Hart en ziel. NRC Handelsblad weekendeditie 1/2 november 2008 159 Swaab, D.F. - Swaab over hersenen. Puberhoofd. NRC Handelsblad weekendeditie 8/9 november 2008 160 Swaab, D.F. - Swaab over hersenen. Puberhoofd 2. NRC Handelsblad weekendeditie 15/16 november 2008 161 Swaab, D.F. - Hoeveel pijn. Relevant. NVVE nr. 4, november 2008. 162 Swaab, D.F. - Swaab over hersenen. Gelukkig. NRC Handelsblad weekendeditie 29/30 november 2008 163 Swaab, D.F. - Boodschappen van God. In: de Telegraaf, zaterdag 4 oktober 2008 164 Swaab, D.F. - Wij zijn onze hersenen. Themabijlage Onze Hersenen. Media Planet, September 2008. 165 Swaab, D.F. - Uit de keuken van de apologie. Discussie over Geneesgebed van Swaab (NRC weekend column). In: Oikodomè, jaargang XII, nr. 3, december 2008, p. 54-64 166. Swaab, D.F. - Getallen als bergen. NRC Handelsblad weekendeditie 13/14 december 2008 167. Swaab, D.F. - Te veel hersens. NRC Handelsblad weekendeditie 20/21 december 2008 168. Swaab, D.F. - Geniaal. NRC Handelsblad weekendeditie 27/28 december 2008 2009 169. Swaab, D.F. - Iedereen savant. NRC Handelsblad weekendeditie 3/4 januari 2009 170. Swaab, D.F. - Brein per kilo. NRC Handelsblad weekendeditie 17/18 januari 2009 171. Swaab, D.F. - De mens in het beest. NRC Handelsblad weekendeditie 31 januari/1 februari 2009 172. Swaab, D.F. - Goed gedrag. NRC Handelsblad weekendeditie, 14/15 februari 2009 173. Swaab, D.F. - Hersenmoraal. NRC Handelsblad weekendeditie, 28 februari/1 maart 2009 174. Swaab, D.F. - Het Juiste Moment. In: Relevant, nr. 1, februari 2009 175. Swaab. D.F. - Weer Baby. NRC Handelsblad weekendeditie, 14/15 maart 2009 176. Swaab, D.F. - Veelplassers. NRC Handelsblad weekendeditie, 28/29 maart 2009 177. Swaab, D.F. - Respijt door een schedelmeting. NRC Handelsblad. 4 mei 2009 95

178. Swaab, D.F. - Strabismus In Een absolute mus. Mussenwoorden in tekst en tekening. Peter Müller, Bert Keizer, p. 28, ISBN 978-90-8138-871-9 179. Swaab, D.F. - Hypothalamus In Een absolute mus. Mussenwoorden in tekst en tekening. Peter Müller, Bert Keizer, p. 100, ISBN 978-90-8138-871-9 180. Swaab, D.F. - Voorwoord in Puberbrein. Binnenstebuiten. Huub Nelis & Yvonne van Sark. 181. Swaab, D.F. - Vloeibaar Vertrouwen. Swaab over Hersenen. In: NRC weekblad (week 9-15 mei 2009). 182. Swaab, D.F. - Vaderskindjes. Swaab over Hersenen. In: NRC weekblad (week 20-27 juni 2009). 183. Swaab, D.F. - De werking van een placebo. In: MS Info, juni 2009. 184. Swaab, D.F. - Samen zullen we niet alleen zijn. NRC Handelsblad, vrijdag 9 oktober 2009 2010 185. Swaab, D.F. - Bén ik nog als ik niet meer denk. In: Relevant. NVVE, no. 2, May 2010. 186. Swaab, D.F. - Om internationaal mee te tellen, moet de overheid Nederlandse universiteiten dwingen tot samenwerking bij wetenschappelijk onderzoek. In: Folia, rubriek Overigens, vol. 63, no. 32, May 2010 187 Swaab, D.F. Voorwoord bij Genderkinderen. Sarah Wong en Ellen de Visser, Uitg. d jonge hond, 2010 188 Swaab, D.F. Foreword of Inside Out, Sarah Wong and Ellen de Visser, d jonge hond Publishing 2010 189 Swaab, D.F. Honderdduizend kilometer vezels. De neurobiologie van angst en agressie bij het kind. Balans Belicht, redactie Arga Paternotte en Miriam de Heer, februari 2011, pp. 22-28. 190 Swaab, D.F. Foreword of Doodeerlijk, by A.A. Wouda 2012 191 Swaab, D.F. De keuze van Dick Swaab, Hersenonderzoeker/schrijver. Bij de tentoonstelling Rollercoaster, MOTI (Museum of the Image, Breda). 192 Swaab, D.F. Overigens. In Folia Magazine nr. 33, 6 juni 2012 193 Swaab, D.F. Hersenverschillen bij identieke tweelingen: waarom zijn we allemaal uniek? 25 years of NTR. 96

ABSTRACTS etc. 1968 Jongkind, J.F. and D.F. Swaab - Enzymatische parameters voor neuro-secretorische activiteit. Negende Federatieve Vergadering van Medisch-Biologische Verenigingen, Nijmegen, 1968. Jongkind, J.F. and D.F. Swaab - Enzymatic parameters for neurosecretory activity. 3rd Int. Congr. of Histochemistry and Cytochemistry, New York, 1968, p. 120 (Springer, New York), 1968. 1969 Swaab, D.F. and J.F. Jongkind - De mogelijkheid van een verband tussen de neurosecretorische activiteit en de gonadotropinen spiegels bij de rat. Tiende Federatieve Vergadering van Medisch-Biologische Verenigingen, Utrecht, 1969. Swaab, D.F. and J.F. Jongkind - The relation between the neurosecretory activity and the level of gonadotropic hormones. Gener. comp. Endocr. 13, p. 533, 1969. 1970 Swaab, D.F. and J.F. Jongkind - The activation of neurosecretory activity by gonadotropic hormones. J. Endocr. 48, xliv-xlv, 1970. 1973 Boer, K. and D.F. Swaab - Telemetric recordings from the rat hypothalamus. J. Endocr. 57, xxxiii-xxxiv, 1973. Boer, G.J., D.F. Swaab and J.F. Jongkind - Lysosomale enzym activiteits-veranderingen in de neurohypophyse van de rat tijdens de activering van het hypothalamusneurohypofyse systeem. Veertiende Federatieve Vergadering van Medisch-Biologische Verenigingen, Groningen, 1973. Boer, G.J., D.F. Swaab and J.F. Jongkind - Changes in enzyme activities of the neurohypophysis after influencing in the hypothalamo-neurohypophysial system of the rat. J. Endocr. 57, xviii, 1973. Honnebier, W.J. and D.F. Swaab - The role of the human foetal brain in the onset of labour. J. Endocr. 57, xxxxxxi, 1973. Honnebier, W.J. and D.F. Swaab - The role of the human and rat foetal hypothalamus upon intrauterine growth of foetus and placenta and on gestation length. Acta Endocr. (Kbh.) Suppl. 177, p. 241, 1973. Honnebier, W.J. and D.F. Swaab - The influence of anencephaly upon intrauterine growth of fetus and placenta and upon gestation length. J. Obstet. Gynaec. Brit. Cwlth. 80, pp. 57788, 1973. Swaab, D.F., G.J. Boer and J.W.L. Nolten - The hypothalamo-neurohypophysial system (HNS) of the Brattleboro rat. Acta endocr. (Kbh.) Suppl. 177, p.80, 1973. Swaab, D.F., W.J. Honnebier and K. Boer - The role of the fetal rat brain in labour. J. Endocr. 57, xxxi-xxxii, 1973. 1974 Honnebier, W.J. and D.F. Swaab - The role of the hypothalamo-hypophysial system in fetal and placental growth. Vijftiende federatieve vergadering van medisch-biologische verenigingen, Nijmegen, 1974. Swaab, D.F. - Neuro-endocriene regulatie van intr-uteriene groei en baring. Ned. T. Geneesk. 118, p. 364, 1974. Swaab, D.F. and W.J. Honnebier - Stimulation of the human fetal adrenal by ACTH and its role in parturition. Fourth International Congress on Hormonal Steroids. J. Steroid Biochem. 5, Abstract 295. Mexico City, 2-7 September, 1974. Swaab, D.F., H.J.G. Hollemans, A.P.M. Schellekens, J.L. Touber, T.E.W. Feltkamp and A.L. Van Rossum - Localization of vasopressin in the hypothalamo-neurohypophysial system (HNS) of the rat by immunofluorescence-histochemistry. Vijftiende Federatieve Vergadering van Medisch-Biologische Verenigingen, Nijmegen, 1974. Swaab, D.F. - De betekenis van het hypothalamus-neurohypofyse systeem voor diurese en voortplanting. Organorama 11(2), 3-9, 1974. 1975 Boer, K., D.W. Lincoln and D.F. Swaab - Effects of electrical stimulation of the neurohypophysis on labour in the rat. Zestiende Federatieve Vergadering van Medisch- Biologische Verenigingen, Utrecht, Abstract p. 159, 1975. Boer, G.J., C. Van Rheenen-Verberg, Y. Koenders, J. Brugge and D.F. Swaab - Cellular localization of the neurohypophyseal acid phosphatase activity increase following water deprivation of the rat. Zestiende Federatieve Vergadering van Medisch-Biologische Verenigingen, Utrecht, Abstract p. 158, 1975. Honnebier, W.J. and D.F. Swaab - Regulation of growth velocity by the foetus. Xth Acta Endocrinologica 97

Congress, Amsterdam, Abstract p. 97, 1975. Swaab, D.F., F. Nijveldt and C.W. Pool - Distribution of oxytocin and vasopressin within the rat hypothalamus. Xth Acta Endocrinologica Congress, Amsterdam, Abstract p. 131, 1975. Swaab, D.F., C.W. Pool, F. Nijveldt, H.J.G. Hollemans, A.P.M. Schellekens and J.L. Touber - The localization of oxytocin and vasopressin in the hypothalamus and neurohypophysis of the rat by immunofluorescence. Zestiende federatieve vergadering van medisch-biologische verenigingen, Utrecht, Abstract p. 362, 1975. Van Leeuwen, F.W. and D.F. Swaab - Immunolocalization of neurohypophyseal hormones in rats at the light and electronmicroscopic level by means of a peroxidase procedure. Zestiende federatieve vergadering van medisch-biologische verenigingen, Utrecht, Abstract p. 274, 1975. Van Wimersma Greidanus, Tj.B., J. Dogterom, J.H.J. Goedemans, R.M. Buijs and D.F. Swaab - Vasopressin and oxytocin content of neurohypophyses of Brattleboro rats, as measured by radioimmuno-assay. Zestiende federatieve vergadering van medisch-biologische verenigingen, Utrecht, Abstract p. 402, 1975. 1976 Dogterom, J., D.F. Swaab and Tj.B. Van Wimersma Greidanus - A possible role of vasopressin in cerebrospinal fluid for memory expression of rats. Zeventiende federatieve vergadering van medisch-biologische verenigingen, Amsterdam, Abstract p. 173, 1976. Honnebier, W.J. and D.F. Swaab - Regulatie van de groeisnelheid door de foetus. Ned. T. Geneesk. 120, pp. 1767-1768, 1976. Swaab, D.F. - Localization of an alpha-msh-like compound in the nervous system by immunofluorescence. Vth Int. Congress of Endocrinology, Hamburg, FRG, Abstract nr. 285, 1976. Swaab, D.F., M. Visser, F.J.H. Tilders and W.J. Honnebier - Stimulation of intra- uterine growth in rat by alpha- MSH. A function for this hormone in mammals. Zeventiende vergadering van medisch-biologische verenigingen, Amsterdam, Abstract p. 373, 1976. Van Leeuwen, F.W. and D.F. Swaab - Immunoelectronmicroscopical localization of neurohypophyseal hormones in rats. Zeventiende federatieve vergadering van medisch-biologische verenigingen, Amsterdam, Abstract p. 274, 1976. Van Leeuwen, F.W. and D.F. Swaab - Specific immunocytochemistry of neurohypophyseal peptides. Ultramicroscopy 2, p. 136, 1976. Dogterom, J., C.M.F. Van Rheenen-Verberg, Tj.B. Van Wimersma Greidanus and D.F. Swaab - Vasopressin and oxytocin in cerebrospinal fluid of rats. J. Endocr. 72, 74P-75P, 1977. Swaab, D.F. - Functional anatomy of the hypothalamus. Boerhaave Committee for postgraduate education "Clinical and Experimental Aspects of Neuroendocrinology", Leyden, 1977. Swaab, D.F. - Hersenen en Ouderdom. Boekbespreking "Aging", Vol. 1: Clinical, Morphological and Neurochemical Aspects in the Aging Central Nervous System, H. Brody, D. Harman and J.M. Ordy (eds.), Raven Press, New York, 1975, 221 pp., voor het Vakblad voor Biologen 57, p. 372, 1977. Swaab, D.F., J. Dogterom, F.W. Van Leeuwen and K. Boer - Arginine-vasotocin in the foetal rat pituitary gland. J. Endocr. 72, 4PP, 1977. Van Leeuwen, F.W. and D.F. Swaab - Specific immunoelectronmicroscopic localization of vasopressin and oxytocin in the rat neurohypophysis. J. Endocr. 72, 62P, 1977. Van Leeuwen, F.W. and D.F. Swaab - Optimalization of ultrastructural immunocytochemistry of rat neurohypophyseal substances. Achtiende federatieve vergadering van medisch-biologische verenigingen, Leyden, Abstract p. 278, 1977. 1978 Buijs, R.M., D.F. Swaab, J. Dogterom and F.W. Van Leeuwen - Intra- en extrahypothalame vasopressine en oxytocine banen in de rat. Ned. T. Geneesk. 122, pp. 734-735, 1978. Pévet, P., D.F. Swaab and P.M. Janssens - Détection immunocytochimique d'une substance immunogiquement apparentée á l'alpha-msh dans la glande pinéale du rat blanc. Proc. IX Colloque de Neuroendocrinologie Expérimentale, Genève, 1978. Pévet, P., J. Dogterom, R.M. Buijs, D.F. Swaab and P.M. Janssens - The presence of neuropeptides in the mammalian pineal and subcommissural organ. Neurosci. Lett. Suppl. 1, Abstract S225, 1978. Swaab, D.F. - Immunohistochemical localization of hormones in the brain and pituitary. 19e federatieve vergadering van medisch wetenschappelijke verenigingen, Rotterdam, 29-31 March, Didactisch symposium, Abstract p. 9, 1978. Swaab, D.F., P.M. Janssens, F.W. Van Leeuwen and G.J. Boer - Alpha-MSH-like compounds in the rat brain. Neurosci. Lett. Suppl. 1, Abstract S230, 1978. Swaab, D.F., F.W. Van Leeuwen, G.J. Boer and P.M. Janssens - Alpha-MSH-like compounds in the developing and in the adult rat brain. Abstract Internat. Symp. on Developmental Neurobiology (IBRO), Teheran, Iran, 98

1978. Van Leeuwen, F.W., R.M. Buijs, D.F. Swaab and C. De Raay - Localization of vasopressin at the light and electronmicroscopical level in the suprachiasmatic-limbic system in rats. Neurosci. Lett. Suppl. 1, Abstract S222, 1978. Visser, M. and D.F. Swaab - Alpha-melanocyte stimulating hormone in the human pituitary. 19e Dederatieve Vergadering van medisch wetenschappelijke verenigingen, Rotterdam, 29-31 March, Abstract p. 56, 1978. 1979 Boer, G.J., D.F. Swaab and H.B.M. Uylings - Neuropeptides and brain development. Seventh Intern. Meeting ISN, Jerusalem, Abstract p. 244, 79. Dogterom, J., P. Pévet, R.M. Buijs, F.G.M. Snijdewint and D.F. Swaab - Vasopressin, oxytocin and vasotocin in pineal gland, subcommissural organ and foetal pituitary: failure to demonstrate vasotocin in mammals. Acta endocr. (Kbh.) Suppl. 225, Vol. 91, p. 413, 1979. Martin, J.T., J. Dogterom and D.F. Swaab - Vasotocin and alpha-msh in the pituitary and hypothalamus of the duck in relation to the imprinting sensitive period. Annual Meeting of the American Society of Zoologists, Tampa, Florida, USA, December 27-30, 1979. Pévet, P., J. Dogterom, R.M. Buijs, I. Ebels, D.F. Swaab and A. Arimura - Presence of alpha-msh-, AVT- and LHRH-like compounds in the mammalian pineal and subcommisural organ and their relationship with the UMO5R pineal fraction. Abstract Xth Conf. of European Comparative Endocrinologists, Sorrento, Italy, May 21-25, 1979. Swaab, D.F. - The Hypothalamus. Research Publications: Association for Research in Nervous and Mental Disease, Vol. 56, S. Reichlin, R.J. Baldessarini and J.B. Martin (Eds.). Raven Press, New York, 1978. Book review in Quart. Rev. Biol. 54, p. 119, 1979. Swaab, D.F. - Immuno-neurocytochemie. Abstract in klapper t.b.v. cursus "Neurochemie", Univ. v. Utrecht, 6-12 June, 1979. Swaab, D.F. - Programs of the Brain, J.Z. Young (Ed.), Oxford University Press, Oxford, 1978. Book review in Theor. Appl. Gen., 1979. Swaab, D.F. - Morfologische en biochemische veranderingen in de hersenen tijdens veroudering. Boerhaave cursus "Dementiën", Algemeen-medische en neurologische aspecten. Boerhaave Commissie voor postacademisch onderwijs in de geneeskunde, Rijksuniversiteit Leiden, 15-16 november, pp. 33-39, 1979. Swaab, D.F. and R.M. Buijs - Life span changes in the presence of melanocyte stimulating hormone containing cells in the human pituitary. J. Developm. Physiol. 1, pp. 161-178, 1979. Van Leeuwen, F.W., D.F. Swaab, C. De Raay and B. Fisser - Immunoelectron-microscopical demonstration of alpha-melanocyte-stimulating hormone-like compounds in the rat brain. J. Endocr. 80, 59P-60P, 1979. Van Leeuwen, F.W., D.F. Swaab, C. De Raay and B. Fisser - Immunoelectron-microscopical localization of alpha-msh-like compounds in the rat brain. Ultramicroscopy 4, p. 125, 1979. 1980 Boer, G.J., D.F. Swaab, R.M. Buijs and H.B.M. Uylings - Neuropeptiden en hersenontwikkeling. Ned. T. Geneesk. 124(7), p. 250, 1980. Buijs, R.M. and D.F. Swaab - Peptides in the central nervous system. Proc. 21st Dutch Federation Meeting, Nijmegen, April 9-11, Abstract Nr. 62, 1980. Buijs, R.M., G.J. De Vries, D.N. Velis and D.F. Swaab - Exohypothalamic vasopressin and oxytocin pathways in the adult and developing rat brain, a light and electron microscopical study. XI Internat. Congr. Internat. Soc. of Psychoneuroendocrinology, Florence, Italy, June 16-20, Abstract p. 28, 1980. Pévet, P., J. Dogterom, R.M. Buijs, I. Ebels, D.F. Swaab and A. Arimura - Presence of alpha-msh-, AVT- and LHRH-like compounds in the mammalian pineal and subcommisural organ and their relationship with the UMO5R pineal fraction. Gen. Comp. Endocrinol. 40(3), 366-367, 1980. Swaab, D.F. - Synthesis, transport and release of peptides in the brain. Proc. 21st Dutch Federation Meeting, Nijmegen, 9-11 April, Abstract Nr. 417, 1980. Velis, D.N., R.M. Buijs and D.F. Swaab - Neurosecretoire cellen en hun exohypothalame vezels tijdens de hersenontwikkeling bij de rat. Ned. T. Geneesk. 124, 855-856, 1980. 1981 Buijs, R.M., G.J. Boer And D.F. Swaab - Hersenfuncties en de betekenis van neuropeptiden. In: Abstractboek PAO-cursus `Nieuwe ontwikkelingen in de Neuroendocrinologie', Vrije Univ., Amsterdam, Sept 25 - Oct. 3, 1981. Fliers, E., D.F. Swaab and C.W. Pool - Changes related to aging in human and rat vasopressinergic and ocytocinergic neurons. In: Proc. Int. Symp. Aging Brain and Ergot Alkaloids', A. Agnoli, G. Crepaldi, P.F. Spano 99

and M. Trabucchi (Eds.), pp. 91-92, Abstr. Book, Rome, Italy, 1981. Swaab, D.F. - Geslachtelijke differentiatie van de hersenen. Verslagen Avondsymposium "Hormonen en sexueel gedrag", pp. 11-19, Organon Nederland b.v., Amsterdam, April 27, 1981. Swaab, D.F. - Life span changes in extrahypothalamic vasopressinergic and oxytocinergic innervation in the brain. In: Proceedings of the XI Conference of the European Society for Comparative Endocrinology, Jerusalem, Israel, August 24-28, Abstract book, 1981. Swaab, D.F. - Neuropeptides and their distribution in the brain. Proc. 12th International Summer School of Brain Research "Chemical Transmission in the Brain", Abstract book pp. 115-116, Amsterdam, 1981. Swaab, D.F., G.J. Boer and R.M. Buijs - Toepassingsmogelijkheden en gevaren van neuropeptiden. In: Abstractboek post-academische cursus `Nieuwe Ontwikkelingen in de Neuroendocrinologie', Vrije Univ., Amsterdam, Sept 25 - Oct. 3, 1981. 1982 Swaab, D.F. - Life span changes in extrahypothalamic vasopressinergic and oxytocinergic innervation in the brain. Gen. Comp. Endocr. 46, 345-413, 1982. Fliers, E., D.F. Swaab and C.W. Pool - The human and rat hypothalamo-neurohypophyseal system (HNS) during aging. 23rd Dutch Federative Meeting, Amsterdam, Nr. 127, 7-8 April, 1982. Swaab, D.F. - Introduction in Manual Second EMBO Practical Course "Immunocytochemistry and its application in brain research", Amsterdam, pp. 29-31, 1982. Swaab, D.F. - Vasopressin and oxytocin neurons in various stages of life. In: Manual Second EMBO Practical Course "Immunocytochemistry and its application in brain research", Amsterdam, pp. 287-293, 1982. Swaab, D.F. - Verklaring van trefwoord "Neurosecretie", Winkler Prins Encyclopedie, Deel 16, p. 316. Elsevier/North-Holland Biomedical Press, Amsterdam, 1982. Swaab, D.F. - Vasopressin and oxytocin in the developing, adult and aging brain. 13th CINP Congress, Symposium "Peptides in the Brain", Jerusalem, Israel, 1982. Swaab, D.F. - Peptiderge verbindingen in het centrale zenuwstelsel. In: Hypothalamus en Hypofyse: pathofysiologie en kliniek, Boerhaave Commissie voor Postacademisch Onderwijs in de Geneeskunde (cursus), Leiden, pp. 43-47, November 11-12, 1982. Swaab, D.F. and E. Fliers - Aging of the brain. 23rd Dutch Federative Meeting, Amsterdam, Nr. 408, April 7-8, 1982. Swaab, D.F., F.W. Van Leeuwen and R.M. Buijs - Preface in Manual Second EMBO practical course "Immunocytochemistry and its application in brain research", Amsterdam, pp. 9-10, 1982. Swaab, D.F., G.J. Boer, H.P. Oosterbaan and P. Oosting - The fetal brain-pituitary-adrenal axis and labour. In: Abstract booklet of IBRO Satellite Symposium on Vasopressin, Corticoliberin and ACTH-related Peptides, Geneva, A-30, March 28-30, 1982. 1983 Swaab, D.F. - Evolution and Tumour. Pathology of the Neuroendocrinology System (1985) book review. Proceedings of the 5th Fernström Symposium, Lund, Sweden, July 3, 1983. Fliers, E. and D.F. Swaab - The human vasopressinergic and oxytocinergic system in relation to sex, aging and dementia. 17th Annual Symp. `Aging 2000; our health care destiny', TRINS, Houston, USA, 1983. Fliers, E. and D.F. Swaab - Vasopressin and oxytocin neurons in the human brain in relation to aging and dementia. Proc. 14th CINP Congress, Florence, Italy, pp. 19-23, 1983. Fliers, E., D.F. Swaab and T. Partiman - The human paraventricular, supraoptic and suprachiasmatic nucleus in relation to sex, aging and dementia. Proc. 13th Int. Summer School of Brain Research, Amsterdam, 62-63, 1983 (also poster). Oosterbaan, H.P. and D.F. Swaab - The contribution of the fetus and the mother to amniotic fluid oxytocin and vasopressin. Proc. of the 24th Dutch Fed. Meet., Leyden, no. 297, 1983. Swaab, D.F. - Book review `Aging of the Brain', Vol. 22, D. Samuel, S. Algeri, S. Gershon, V.E. Grimm and G. Toffono (Eds.). Raven Press, NY, 1983, T. Gerontologie en Geriatrie, in press, 1983. Swaab, D.F. - Prenatal brain disturbances by chemicals. Neuropediatrics 14, 124, 1983. Swaab, D.F. and E. Fliers - Neuropeptides, memory and aging. Proc. Symp., `The aging brain, dementia and memory impairments', Nijmegen, 1983. Swaab, D.F. and E. Fliers - De wenselijkheid van een `hersenbank' voor onderzoeksmateriaal van demente patienten. Proc. SOOM Workshop, `Dementie onderzoek', Amsterdam, 1983. Swaab, D.F. and M. Hofman - Sexual differentiation of the brain. A historical perspective. Proc. 13th Int. Summer School of Brain Research, Amsterdam, 115-116, 1983. Van de Poll, N.E., A.M.M.C. Habets and D.F. Swaab - Book review `Adrenal actions on brain, current topics in neuroendocrinology', Vol. 2, D. Ganten and D. Pfaff (Eds.). Springer Verlag, New York, 1982. Mol. cell. 100

Endocrinol. 31, 161-162, 1983. 1984 Boer, G.J., D.F. Swaab, H.P. Oosterbaan and F.G.M. Snijdewint - Neuropeptides in development. J. Endocrinol. 102, S72, August, 1984. Fliers, E. and D.F. Swaab - Vasopressin and oxytocin neurons in the human brain in relation to aging and dementia. 8th European Neuroscience Congress, The Hague, The Netherlands, September 11-15, 1984. Neurosci. Lett. 18, S342, 1984. Fliers, E. and D.F. Swaab - Vasopressin and oxytocin neurons in the human brain in relation to aging and senile dementia. Proc. 14th Int. CINP Congr., Florence, Italy, S277, 1984. Hoogendijk, J.E., E. Fliers and D.F. Swaab - Het humane hypothalamo-neurohypophyseale systeem tijdens veroudering. Vakbl. Biol. 64, 429-430, 1984. Oosterbaan, H.P., D.F. Swaab and G.J. Boer - The origin of amniotic oxytocin and vasopressin in their relationship to intrauterine growth. Symp., `Physiological Development of Fetus and Newborn', Oxford, UK, 1984. Ravid, R., D.F. Swaab and C.W. Pool - Light microscopic immunocytochemical localization of vasopressin binding sites in the rat kidney. 1984 Regional Meet. of the Int. Union of Physiol. Sci., Jerusalem, Israel, August 26-31, 1984. Swaab, D.F. - Book review `Evolution and tumour pathology of the neuroendocrine system', Proc. of the 5th Eric K. Fernström Symposium, Lund, Sweden, July 3, 1983, S. Falkmer, R. Haakanson and F. Sundler (Eds.), Elsevier, Amsterdam, New York, Oxford, 1984, J. Neurol. Sci. 69, 117-118, 1985. Swaab, D.F. - Permanente effecten van chemische stoffen op de hersenontwikkeling. Proc. 36th Repetition Course Kindergeneeskunde, 1984. Swaab, D.F. - Peptiden in de menselijke hersenen. Symposium Biologische Raad: Amsterdam, Nov. 2nd, `Neuropeptiden, hersenen en gedrag', 1984. Swaab, D.F. and E. Fliers - Possibilities and limitations of immunocytochemistry on human postmortem brain material. Proc. ETP Winter School, Zuoz, Switzerland, 1984. Swaab, D.F. and E. Fliers - Immunocytochemistry; recent applications to the human brain. ENA satellite workshop/boerhaave course: "Modern techniques in the study of the morphology of the nervous system", September 17-18, Leyden, 1984. Swaab, D.F., E. Fliers and T. Partiman - The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia. 8th European Neuroscience Congress, The Hague, September 11-15, 1984, Neurosci. Lett. Suppl. 18, S327, 1984. Swaab, D.F., H.P. Oosterbaan and E. Fliers - Localization of neuropeptides in the brain: life-span changes. Int. Symp., 'Perspectives in Aetiology of Psychiatric Disorder', Rotterdam, April 19, 1984. Swaab, D.F. - Wetenschappelijke puberteit, een oprukkende laboratoriumziekte. Vakblad voor Biologen 64(20), 446, 1984. 1985 Boer, G.J., F.G.M. Snijdewint, J. Kruisbrink, D.F. Swaab and M. Manning - Developmental effects of perinatal treatment with vasopressin, its antagonist and heterologues in Wistar and Brattleboro rat. 5th Ann. Meet. Society for Neuroscience, Dallas, USA, nr. 186.9, 1985. Fliers, E., G.J. De Vries and D.F. Swaab - Changes with aging in the vasopressin and oxytocin innervation of the rat brain. 26ste Federatieve Vergadering van Medisch Wetenschappelijke Verenigingen in Nederland, Academic Medical Center, Amsterdam, April 11-12, Abstract nr. 97, 1985. Fliers, E., J.E. Hoogendijk and D.F. Swaab - Vasopressin and oxytocin neurons in the human brain; changes with aging and in senile dementia. Vergadering der Amsterdamsche Neurologenvereeniging, December 6, J. Clin. Neurol. & Neurosurg. 87, 76-77, 1985. Fliers, E. and D.F. Swaab - Neuropeptide changes in aging and Alzheimer's disease. 14th Int. Summer School of Brain Research "Aging of the Brain and Senile Dementia", Amsterdam, August 26-30, Abstract book pp. 30-31, 1985. Goudsmit, E., E. Fliers and D.F. Swaab - Unaltered neuron numbers in the human supraoptic and paraventricular nucleus with aging and senile dementia. 14th International Summer School of Brain Research "Aging of the Brain and Senile Dementia", Amsterdam, August 26-30, Abstract book p. 71, 1985. Hoogendijk, J.E., E. Fliers and D.F. Swaab - Vasopressin and oxytocin neurons in the human hypothalamus; changes with aging and dementia. 26ste Federatieve Vergadering van Medisch Wetenschappelijke Verenigingen in Nederland, Academic Medical Center, Amsterdam, The Netherlands, April 11-12, Abstract nr. 144, 1985. Hoogendijk, J.E., E. Fliers, D.F. Swaab and R. Ravid - Het vasopressine neuron in de menselijke hersenen; 101

veranderingen tijdens veroudering. Abstract Nederlandse Vereniging voor Endocrinologie, NTVG 129, 2429-2430, 1985. Mirmiran, M. and D.F. Swaab - Neurochemical and electrophysiological disturbances during development mediate behavioral teratogenicity of medicines. Symp and Workshop `Design Considerations in Screening for Behavioral Teratogens: Results of the Collaborative Behavioral Teratology Study', Cincinatti, USA, September 3-6, poster, 1985. Mirmiran, M. and D.F. Swaab - Central neurotransmitter disturbances underlying developmental neurotoxicological effects. 4th Int. Conf., `Neurotoxicology of Selected Chemical: Neurotoxicology in the Fetus and Child', Little Rock, USA, September 9-13, pp. 14-15, 1985. Oosterbaan, H.P., D.F. Swaab, G.J. Boer and R. Ravid - Amniotic fluid oxytocin and vasopressin in the human and the rat. Werkgroep voor Perinatale Biologie. November 1, p. 6, 1985. Ravid, R., D.F. Swaab, T.P. Van der Woude and G.J. Boer - Immunocytochemical staining of vasopressin binding sites in the rat brain. In: Proceedings of the 26th Dutch Federation Meeting, Amsterdam, April 11-12, Abstract nr. 273, 1985. Ravid, R., D.F. Swaab, T.P. Van der Woude and G.J. Boer - Immunocytochemical staining of vasopressin binding sites in the rat brain. Neurosci. Lett., Suppl. 22, S392, 1985. Ravid, R., D.F. Swaab, T.P. van der Woude and G.J. Boer - Immunocytochemical staining of vasopressin binding sites in the rat brain. 15th Ann. Meet. Society for Neuroscience, Dallas, USA, nr. 234.6, 1985. Snijdewint, F.G.M., G.J. Boer, T.P. Van der Woude and D.F. Swaab - Effects of vasopressin administration to the homozygous Brattleboro rat and vasopressin antagonists to the Wistar. In: Proceedings of the 26th Dutch Federation Meeting, Amsterdam, April 11-12, Abstract 323, 1985. Swaab, D.F. - Evolution and tumour pathology of the neuroendocrine system. In: Proceedings of the 5th Eric K. Fernström, Lund, Sweden, S. Falkmer, R. Haakanson and F. Sundler (Eds.), July 3, 1983, Elsevier, Amsterdam/Oxford/New York, book review. J. Neurol. Sci. 69, 117-118, 1985. Swaab, D.F. - Inleiding voor boek `Zwangerschap en medicijngebruik', U. Bittner, R. Jackle, C. Scholz, I. Dakman and F. Groenestijn (Eds.), ELMAR, 1985. Swaab, D.F. - Boekbespreking: Zenuwweefsel: groei en herstel. Ned T. Geneesk. 129(1), 39, 1985. Swaab, D.F. - A brain-bank in the Netherlands, Eurage workshop: Clinical Pathological and Neurochemical Opportunities for Collaborative Research in Dementia, June 5-7, Newcastle-upon-Tyne, UK, 1985. Swaab, D.F. - Peptiden in de menselijke hersenen. Capita Selecta, Faculteit der Geneeskunde, Erasmus Univ., Rotterdam, 6 March, 1985. Swaab, D.F. and E. Fliers - A sexually dimorphic nucleus in the human brain. Neurosci. Lett., Suppl. 22, 1985. Swaab, D.F. and E. Fliers - Clinical strategies in the treatment of Alzheimer's disease. 14th International Summer School of Brain Research "Aging of the Brain and Senile Dementia", Amsterdam, August 26-30, Abstract book pp. 512, 1985. Swaab, D.F., E. Fliers and M.A. Hofman - Sexual dimorphism of the human brain. Vergadering der Amsterdamsche Neurologenvereeniging, December 6, J. Clin. Neurol. & Neurosurg. 87, 77-78, 1985. Swaab, D.F. and M. Mirmiran - Possible mechanisms underlying the functional teratological effects of medicines on the developing brain. Abstract 2nd European Symposium on Developmental Neurology, Hamburg, FRG, Abstract book, May 15-18, 1985. Swaab, D.F. and M. Mirmiran - Functional teratological effects of chemicals on the developing brain. Symposium on Systemic Hormones, Neurotransmitters and Brain Development, Berlin, GDR, September 12-14, 1985. Swaab, D.F. and M. Mirmiran - Mechanisms underlying functional teratogenic effects on the developing brain. Royal Postgraduate Medical School, `Update in Neonatal Neurolo-gy'. Hammersmith Hospital, London, UK, November 18-22, 1985. 1986 Goudsmit, E., E. Fliers and D.F. Swaab - Unaltered cell numbers in the human supraoptic and paraventricular nucleus with aging and in Alzheimer's disease. Proc. 27th Dutch Fed. Meeting, Groningen, April 2-3, Abstract nr.138. Goudsmit, E., D.F. Swaab and E. Fliers - Differential cell loss in the hypothalamus anterior with aging and in Alzheimer's disease. Xth. Int. Congr. Neuropathology, Stockholm, Abstract nr. 610 (p.303). Goudsmit, E., D.F. Swaab and E. Fliers - Het effect van testosteron suppletie op de afgenomen vasopressine innervatie in het brein van de oude rat. Retraite MEDIGON Dwarsverband Gerontologie. Stevensbeek, November 7-8, 1986. Goudsmit, E. and D.F. Swaab - Effecten van testosteron suppletie op de afgenomen vasopressine innervatie in het brein van de oude rat. Retraite MEDIGON Dwarsverband Gerontologie. Stevensbeek, November 7-8, 1986. Oosterbaan, H.P., R. Ravid and D.F. Swaab - De foetale bijnier als bron van oxytocine en vasopressine. Ned. 102

Ver. v. Obstetrie en Gynaecologie, 1986. Oosterbaan, H.P., D.F. Swaab, G.J. Boer and R. Ravid - Amniotic fluid oxytocin and vasopressin in the human and the rat. Eur. J. Obstet. Gynaecol. Reprod. Biol. 22, 262/263, 1986. Prechtl, H.F.R. and D.F. Swaab - Ultra-geluidsonderzoek van foetaal gedrag. In: Jubileumboek 25 jaar FUNGO `Beterschap door Wetenschap', pp.130-131, 1986. Ravid, R., D.F. Swaab, G.J. Boer and E. van Zwieten - Immunocytochemically stained bindingsites for oxytocin and alpha-msh in rat brain following ventricular administration. Neurosci. Lett., Suppl.26, S617, 1986. Ravid, R., D.F. Swaab and E. Fliers - Changes in vasopressin neurons in the brain in senescence due to peripheral alterations. Symp., Neuropeptides and Brain Function, Utrecht, May 28-30, 1986. Ravid, R., D.F. Swaab, E. Fliers and J.E. Hoogendijk - Changes in vasopressin neurons in the brain in senescence due to peripheral alterations. EURAGE- meeting, Gerontology 2000, Int. Symp. on Modern Trends in Aging Research, Paris, France, 1986 Ravid, R., D.F. Swaab, E. Fliers and E. Van Zwieten - Immunocytochemically stained administration. Xth Eur. Neuroscience Meet., Marseille, France, 1986. Swaab, D.F. - Book review: Neuroendocrine Perspectives, Vol. 4, E.E. Müller et al. (Eds.). Elsevier Science Publishers, Amsterdam. In: J. Neurol. Sci.75, 363-364, 1986. Swaab, D.F. - De hersenontwikkeling van het kind bij de verslaafde moeder. Symposium "Kind van de verslaving", Fac. Geneeskunde, Erasmus Univ., Rotterdam, February 28, 1986. Swaab, D.F. - Cimetidine of ranitidine? Ned. T. Geneesk. 130, 1373-1974, 1986. Swaab, D.F. - Sexual dimorphism of the human brain. Int. Acad. of Sex Research. Twelfth Ann. Meet., Amsterdam, September 16-20, p.45, 1986. Swaab, D.F. and E. Fliers - Vasopressin systems in the rat and human brain: their changes in relation to aging and Alzheimer's disease. III Reinhardsbrunn Symp., `Circumventricular Organs and Brain Fluid Environment', GDR, March 30 - April 4, 1986. Swaab, D.F. and E. Fliers - Zijn melatonine en tryptofaan ook slaapmiddelen? Ned. T. Geneesk. 130, 926-927, 1986. Swaab, D.F., E. Fliers, L. Gooren and R. Williams - The human suprachiasmatic nucleus in relation to aging and various psychopathologies. Scientific Meeting Biological Measures, their Theoretical and Diagnostic Value in Psychiatry, Noordwijk, September 10-11, 1986, nr.44 Swaab, D.F., E. Fliers, L. Gooren and R. Williams - Vasopressin (AVP) in the human brain in relation to various psychopathologies. Neurosci. Lett., Suppl.26, S14, 1986. Swaab, D.F., E. Fliers, L. Gooren and R. Williams - Vasopressin (AVP) in the human brain in relation to various psychopathologies. Symposium `Neuropeptides and brain Function', May 28-30, Utrecht, Abstract nr. S27. Swaab, D.F., E. Fliers, E. Goudsmit and H.B.M. Uylings - Brain sampling and preservation of specimens for morphology. EURAGE-meeting, Gerontologie 2000, Int. Symp. on Modern Trends in Aging Research. Paris, March 12-14, 1986. 1987 Buijs, R.M. and D.F. Swaab - Book review: `Handbook of Chemical Neuroanatomy, Vol.4 GABA and Neuropeptides in the CNS, part I', 1985, Eds.: A. Björklund and T. Hökfelt. J. Neurol. Sci.79, 241-242, 1987. Fliers, E. and D.F. Swaab - Hersencellen 2. NRC Handelsblad, May 7, 1987. Fliers, E., E. Goudsmit and D.F. Swaab - Changes in the aging human and rat hypothalamus. Federa 1987. Fliers, E., E. Goudsmit and D.F. Swaab - Changes in the aging human and rat hypothalamus. Symp. `Aging of the Central Nervous System'. 28th Dutch Fed. Meet., 1987. Goudsmit, E., E. Fliers and D.F. Swaab - Differentiele veranderingen in de hypothalamus anterior tijdens verandering en bij de ziekte van Alzheimer. Neuroanatomen Methodendag, Erasmus Univ., Rotterdam, p.24, 1987. Goudsmit, E., E. Fliers and D.F. Swaab - Differential cell loss in the hypothalamus anterior with aging and in Alzheimer disease. Autumn Meet. of the Dutch Soc. for Cell. Biology and Symp., `Cell Biological Basis of Ageing', 1987. Goudsmit, E., E. Fliers and D.F. Swaab - Restoration of the vasopressin innervation in the senescent rat brain by testosterone supplementation. In: Clinical Neurology and Neurosurgery, SupplI, Vol.89(2), nr.25, 1987. Mirmiran, M., D.F. Swaab, W.A. Van Gool and W. Witting - The importance of studying `circadian rhythm' in aging and Alzheimer's disease. Neuroscience Suppl., Vol.22, 2516P, 1987. Mirmiran, M., W.A. Van Gool, W. Witting and D.F. Swaab - The importance of studying `circadian rhythm' in aging and Alzheimer's disease. In: Clinical Neurology and Neurosurgery, Vol.89(2), nr.01, 1987. Oosterbaan, H.P., R. Ravid and D.F. Swaab - De bijnier van de foetus als bron van oxytocine en vasopressine. Ned. T. Geneesk.131, 1644, 1987. Oosterbaan, H.P. and D.F. Swaab - Glucocorticoiden in de zwangerschap: effecten op de foetus en 103

pasgeborene. Ned. T. Geneesk.131, 170-1 1987. Ravid, R., E. Fliers and D.F. Swaab - Changes in vasopressin and testosterone in the senescent rat result in alterations in the brain. Conf. Eur. Region of Int. Association of Gerontology, Symp. `Ageing Well', p.27, 1987. Ravid, R., E. Fliers and D.F. Swaab - Peripheral changes in the senenscent rat result in alterations in the brain. T. Soc. Gezondheidszorg 9, 287, 1987. Ravid, R., E. Fliers, D.F. Swaab and E.J. Van Zwieten - Changes in vasopressin and testosterone in the senescent rat result in alterations in the brain. In: Clinical Neurology and Neurosurgery, SupplI, Vol.89(2), nr.26, 1987. Ravid, R., E. Van Zwieten and D.F. Swaab - Vasopressin production sites in slices of rat and human brain. Neuroscience Suppl., Vol.22, 407P, 1987. Schultz-van Dongen, E., E. Goudsmit, D.F. Swaab, F.J.H. Tilders and F. Berkenbosch - Demonstration of corticotropin-releasing factor neurones in the paraventricular nucleus of human subjects including cases of Alzheimer's disease. Clin. Neurol. Neurosurg., SupplI, Vol.89(2), nr.24, 1987. Swaab, D.F. - Postnatal sexual differentiation of the human hypothalamus. Neuroscience Suppl., Vol.22, 473P, 1987. Swaab, D.F. - What may go wrong in brain development due to chemicals? Abstr. PAO cursus Kindergeneeskunde AMC p.14, 1987. Swaab, D.F. - Sexual differentiation of the human hypothalamus. Acta Anat.130, p.90, 1987. Swaab, D.F. - Circadian rhythms, age and Alzheimer's disease. Conf. Eur. Region of Int. Association of Gerontology, Symp. `Ageing Well', p.26, 1987. Swaab, D.F. - Book review: `Neuroendocrine Perspectives', Vol.5. E.E. Müller and R.M. MacLeod (Eds.), Elsevier Biomedical Press, Amsterdam. J. Neurol. Sci.78, 238-239, 1987. Swaab, D.F. - Book review: Neural Regeneration. Progress in Brain Research, Vol.71, F.J. Seil, E. Herbert and B.M. Carlson (Eds.), Elsevier Biomedical Press, Amsterdam. J. Neurol. Sci.81, 113, 1987. Swaab, D.F. - Book review: Brain Peptides Update, Volume 1, J.B. Martin, M.J. Brownstein and D.T. Krieger (Eds.), John Wiley & Sons, New York. J. Neurol. Sci. 82, 309, 1987. Swaab, D.F. and E. Fliers - De organisatie van een Nederlandse hersenbank. SOOM Symp. 'Wijzer over Ouder', p.112, 1987. Swaab, D.F. and E. Fliers - The 14h International Summer School of Brain Research: Aging of the Brain and Alzheimer's Disease. SOOM Symp. `Wijzer over Ouder', p.113, 1987. Swaab, D.F. and W.A. Van Gool - Omgevingsstimulatie, slaappatronen en circadiane ritmen tijdens veroudering. SOOM Symp. `Wijzer over Ouder', p.75, 1987. Swaab, D.F., E. Goudsmit, R. Ravid and H.B.M. Uylings - Neuronal plasticity in senescence. Autumn Meet. Dutch Soc. for Cell Biology and Symp. `Cell Biological Basis of Ageing', Eur. J. Cell Biol., Vol.44, Suppl.20, p.27, 1987. Swaab, D.F. and M.A. Hofman - Postnatal sexual differentiation of the human hypothalamus. 15th Int. Summer School of Brain Research: Neurochemistry of functional neuroteratology, permanent effects of chemicals on the developing brain, Amsterdam, August 31-September 4, p.89, 1987. Swaab, D.F. and H.B.M. Uylings - Mogelijkheden en moeilijkheden bij het neurobiologische onderzoek van menselijk weefsel. E.M. Verhaart groep, Neuroanatomische Methodendag, Rotterdam, p.7, June 5, 1987. Swaab, D.F. G.J. Boer and M. Feenstra - Concept of functional neuroteratology and the importance of neurochemistry. 15th Int. Summer School of Brain Research: Neurochemistry of Functional Neuroteratology, Permanent Effects of Chemicals on the Developing Brain, Amsterdam, August 31-September 4, p.63, 1987. Van Zwieten, E.J., R. Ravid, Tj. Van der Woude and D.F. Swaab - Immunocytochemically stained vasopressin binding sites on blood vessels in rat brain. Dutch J. Zool., in press. 1988 Gooren, L., J.J. Spijkstra, T. Spinder, D. Swaab and M. Mirmiran - Circadian rhythms in transsexuals. Neuroendocrinol. Lett. 10, 241, 1988. Goudsmit, E. and D.F. Swaab - Ageing of the central nervous system: not all downhill. 29th Dutch Fed. Meeting, Utrecht, abstr. 135, 1988. Goudsmit, E., D.F. Swaab and E. Fliers - Veroudering van hersenen en zenuwstelsel. Tijdschr. Gerontol. Geriatr. 19, 264-265, 1988. Goudsmit, E., E. Fliers and D.F. Swaab - Reversibility of changes in vasopressin innervation in the senescent rat brain. Neuroendocrinol. Lett. 10, 204, 1988. Goudsmit, E., E. Fliers and D.F. Swaab - Changes in vasopressin neurons and fibers with aging and in Alzheimer's disease; reversibility in the rat. Alzheimer Disease and Associated Disorders 2, p. 215. Mirmiran, M., W. Witting, D.F. Swaab and P. Eikelenboom - Circadian rhythms in Alzheimer's disease. Neuroendocrinol. Lett. 10, 216, 1988. 104

Mirmiran, M., D.F. Swaab, W. Witting, P. Eikelenboom, B. Honnebier and W.A. Van Gool - Biologiocal clock dysfunction during development and aging. Abstr. Ist Int. Symp. on Mental Retardation, Malnutrition and Aging, OASI, Troina, Sicily, Italy, October 16-20, 1988. Oosterbaan, H.P., R. Ravid and D.F. Swaab - De foetale bijnier als bron van oxytocine en vasopressine. Ned. Tijdschr. v. Obstet. & Gyn. 101, 124, 1988. Oosterbaan, H.P. and D.F. Swaab - Is there still a role for oxytocin (OXT) in the initiation of labor? XIIth World Congr. Gynecology and Obstetrics, Rio de Janeiro, Brasil, October 23-28, p. 491, 1988. Ravid, R., W. Kos, D.F. Swaab and E.J. Van Zwieten - Age related changes in vasopressin production sites in fresh brain slices of senescent rat brains. Neuroendocrinol. Lett. 10, 269, 1988. Ravid, R., E.J. Van Zwieten, D.F. Swaab and W. Kos - The use of fresh brain slices and immersion fixation: a new method for immunocytochemical detection of vasopressin producing neurons in rat and human brain. Methodendag, Free Univ., Amsterdam, May 2, 1988. Ravid, R., E.J. Van Zwieten, D.F. Swaab and Tj.P. Van der Woude - Immunocytochemically stained vasopressin binding sites on blood vessels in the rat brain. Abstr. 11th Ann. Meet. Eur. Neuroscience Ass., Zürich, p. 110, Sept. 4-8, 1988. Swaab, D.F. - Therapeutische strategieën voor de ziekte van Alzheimer. Abstr. in "Van Cel tot Medicijn", Ned. Ver. Farmaceutische Wetenschappen, p. 15, Oct. 27, 1988. Swaab, D.F. - Dementie, ziekte van Alzheimer. Symp. `Ouderdom en geneesmiddelen'. Leiden, 22 January. Abstr. p.30-32, 1988. Swaab, D.F. - Book review: Regulatory peptides in Digestive, Nervous and Endocrine systems. M.J.M. Lewin and S. Bonfils (Eds.). Inserm Symp. no.25, Elsevier, Amsterdam (1987). J. Neurol. Sci. 85, 348, 1988. Swaab, D.F. - Book review: Receptor and Ligands in Neurological Disorders. A.K. Sen and T. Lee (Eds.), Vol.4, Cambridge Univ. Press, Cambridge (1988). J. Neurol. Sci. 88, 347, 1988. Swaab, D.F. - Neurons in ageing and Alzheimer's disease. Symp. `Cellular Pathol. and Ageing'. Combined Meeting Neth. Pathol. Anatom. Soc. and Pathol. Soc. of Great Britain and Ireland, p.2. Maastricht, May 4-6, 1988. Swaab, D.F. - Geslachtsverschillen in de menselijke hersenen. Lustrum Symp. SAMS LAOCOON `Een wereld van verschil', Programmaboekje, p.8, Utrecht, April 8, 1988. Swaab, D.F. - En de student die kiest een opleider... Biovisie 68, 174, 1988. Swaab, D.F. - Circadian Rhythms, aging and Alzheimer's disease. Symp. `The Future of Psychogeriatrics'. Abstractbook, p.10, Drachten, March 24-25, 1988. Swaab, D.F. and E. Goudsmit - Vasopressin and oxytocin in the rat and human brain in relation to sex and age. Abstr. 11th Ann. Meet. of the Eur. Neurosci. Ass., Zürich (Switzerland), Septembre 4-8. Abstr. 34.2, p. 121, 1988. Swaab, D.F., E. Goudsmit and M.A. Hofman - The human hypothalamus in aging and Alzheimer's disease. Psychopharmacology, Suppl. 96, abstr. WE 04.07, p. 53, 1988. Swaab, D.F., M.A. Hofman and B. Fisser - Sexual differentiation of the human hypothalamus. Abstr. 11th Ann. Meet. of the Eur. Neurosci. Ass., Zürich (Switzerland), September 4-8, Abstr. 7.2, p. 8, 1988. Swaab, D.F., M.A. Hofman and B. Fisser - Sexual differentiation of the human brain. Neuroendocrinol. Lett. 10, 222, 1988. Van der Post, J.A.M., J.J. Van Heerikhuize, K. Boer and D.F. Swaab - Vasopressin assay in pregnancy. ISSPH Meet., Montreal, Canada, May 22-28. Abstr. no.240, p.264, 1988. Witting, W., M. Mirmiran, P. Eikelenboom, I.H. Kwa, W.A. Van Gool and D.F. Swaab - Disturbances in the circadian rest-activity rhythm of Alzheimer patients. Sleep Res. 17, 402, 1988. 1989 Goudsmit, E. and D.F. Swaab, Neuroendocrine aspects of normal and pathological aging, 4th meeting of the ENEA, Spain, June 28-30, 1989. J. Endocrinol. Invest. 12 (Suppl. 2), p. 20, 1989. Goudsmit, E., M.G.P. Feenstra and D.F. Swaab, Monoamine metabolism in the rat brain in relation to aging and testosterone: differential changes in mesocortical projections, 16th International Summer School of Brain Research, Amsterdam, August 28 - September 1, 1989. Goudsmit, E., J.S. Purba, M.A. Hofman, C.J.J. Bogte, and D.F. Swaab - Changes in vasopressin and oxytocin cells in the human hypothalamus with aging and in Alzheimer's disease. Eerste Lustrumbijeenkomst Medigon- Dwarsverband Gerontologie, Egmond aan Zee, 23-24 November. Honnebier, H.B.O.M., W. Witting, D.F. Swaab, J.P. Figueroa and P.W. Nathanielsz - Use of an acceleration detector (RA-24) to record rest-activity patterns in tethered pregnant Rhesus Monkeys. Soc. for Gynecologic Investigation. Abstract no. 177, San Diego (USA) 16 March. Kremer H.P.H., D.F. Swaab, G.Th.A.M. Bots, R.A.C. Roos - The hypothalamic lateral tuberal nucleus in HD and AD. Eerste Lustrumbijeenkomst Medigon-Dwarsverband Gerontologie, Egmond aan Zee, 23-24 November. 105

Ravid, R. and D.F. Swaab - Brain Banking in Multiple Sclerosis - The bridge between clinic and animal models. Proceedings 5th Ectrims Congress on Recent Advances in MS Therapy. R.E. Gonsette and P. Delmotte (eds.) Elsevier Science Publishers. Ravid, R. and D.F. Swaab - De Nederlandse hersenbank: een brug tussen hersenonderzoek en kliniek. Ned. Ver. Neuropathologie/Ned. Anatomen Vereniging, Nijmegen, 29 September, pp. 1-2. Ravid, R. and Swaab, D.F. - The Netherlands Brain Bank - a bridge between clinic and brain research. Eerste Lustrumbijeenkomst Medigon-Dwarsverband Gerontologie, Egmond aan Zee, 23-24 November. Ravid, R., E.J. van Zwieten, D.F. Swaab, D. Smyth, A.J. Sluiter, P. van der Sluis and Chr.W. Pool - Vasopressin producing neurons in rat brain and in Alzheimer patients. Proceedings of the International Congress on "Aging of the brain and dementia - ten years later", Florence, May 31 - June 3, pp. 96. Ravid, R., E.J. van Zwieten, D.F. Swaab and Tj. van der Woude - Light microscopic immunocytochemical localization of vasopressin binding sites on blood vessels in the rat brain. International Conference on the Neurohypophysis, Copenhagen, 2-5 July. Swaab, D.F. - Book review "Psychofarmaca: Hersenen onder invloed". Solomon H. Snyder, Deel 15 van de Wetenschappelijke Bibliotheek, Natuur en Techniek. Swaab, D.F. - Brain aging and Alzheimer's disease: "wear and tear" versus "use it or lose it". World Fed. of Neurology, Aging of the Brain and Dementia: 10 years later, Florence, May 31 - June 3, p.11 Swaab, D.F. - De hypothalamus bij de ziekte van Alzheimer. Ned. Ver. Neuropathologie/Ned. Anatomen Vereniging, 29 September 1989, Nijmegen. Swaab, D.F. and M. Mirmiran - Book review: Neuromethods, Vol.9, The Neuronal Microenvironment, A.A. Boulton, G.B. Baker and W. Walz (Eds.), Humana Press, Clifton, New Jersey, USA. J. Neurol. Sci. 89, 325-326, 1989. Swaab, D.F., E. Goudsmit, M.A. Hofman and M.B.O.M. Honnebier - Vasopressin (AVP) in the human hypothalamus in relation to development, aging and reproduction. International Conference on the Neurohypophysis, 2-5 July, Copenhagen, 1989. Swaab, D.F. - antwoord op "Blijvende effecten van chemische stoffen op het zich ontwikkelende zenuwstelsel". Functionele teratologie. Nederlands Tijdschrift voor Geneeskunde 133, 953-954, 1989. Troost, D., J.M.B.V. de Jong, D.F. Swaab - Neurofilament alterations in the cerebral cortex in amyotrophic lateral sclerosis. Ned. Ver. Neuropathologie/ Ned. Anatomen Ver., 29 September 1989, Nijmegen. Van der Post, J.A.M., J.J. Van Heerikhuize, K. Boer and D.F. Swaab - Vasopressin and oxytocin assay in pregnancy. Federa Symp. `Hormonal regulation of fluid and sodium homeostasis during pregnancy', Maastricht, March 29, 1989, pp.6-7. Van der Post, J.A.M., J.J. Van Heerikhuize, K. Boer and D.F. Swaab - Vasopressin and oxytocin radio-immunoassay in pregnancy. AIO-symposium van de Faculteit Geneeskunde, AMC, Univ. v. Amsterdam, 18 October 1989. Van Eerdenburg, F.J.C.M., P. Poot, D.F. Swaab, F.W. van Leeuwen, and G.J. Molenaar, Neuron formation during puberty in a new AVP & OXT containing nucleus in the pig hypothalamus. 3rd International Conference on the Control of the Onset of Puberty, Amsterdam, May 7-10, 1989. Van Eerdenburg, F.J.C.M., C.W. Pool, W. Hoogendijk and D.F. Swaab - Computer assisted method for drawing a border around cell clusters. Eur. J. Neurosci., Suppl. 2, 39. Van Eerdenburg, F.J.C.M., Poot, P., Molenaar, G.J., Van Leeuwen, F., Swaab, D.F., Postnatal development of a new VP & OT containing nucleus (VON) in the pig hypothalamus, Third International Conference on Pig Reproduction, Abstr. 10, Nottingham, 1989 Van Zwieten, R.J., Ravid, R. and Swaab, D.F. - Post mortem effects on vasopressin producing neurons in the suprachiasmatic nucleus of the Wistar rat. Eerste Lustrumbijeenkomst Medigon-Dwarsverband Gerontologie, Egmond aan Zee, 23-24 November 1989 Vivien-Roels, B., D. Skene, D. Arendt, P. Pevet and D.F. Swaab - Melatonine et 5-methozytryptophol dans la glande pineale humaine: presence d'un rythme nyothemeral chez l'adolescent et l'adulte. French Society of Endocrinology. IX. Congres Francais d'endocrinologie, Strasbourg, 12-14 October 1989. Annales d'endocrinologie 50 (4), 270, 1989. Witting, W., Mirmiran, M., Swaab, D.F., Alterations in the circadian rest-activity rhythm in aging and Alzheimer's disease. Eerste Lustrumbijeenkomst Medigon-Dwarsverband Gerontologie, Egmond aan Zee, 23-24 November 1989. 1990 Duyckaerts, C., A.L. Abbamondi-Pinto, I. Allen, J.P. Brion, P. Delaère, L. Duchen, J. Flament-Durand, J.-J. Hauw, J. Kauss, J. Lowe, A. Probst, R. Ravid, K. Renkavek, W. Schlote, S. Sorbi, D.F. Swaab, B. Tomlinson - Rating of the lesions in senile dementia of the Alzheimer type: Concordance between laboratories. Neurobiology of Aging 11, 268, Abstr. 65, 1990. 106

Goudsmit, E., E. Fliers and D.F. Swaab - Changes in vasopressin cells and fibers with aging and in Alzheimer's disease. Proceedings Third International Vasopressin Conference, Montpellier, France, 5-10 August 1990, Abstract B3. Hofman, M.A. and D.F. Swaab - Sexual dimorphism of the human brain: Myth and reality. 3rd International Berlin Conference for Sexology, Berlin, 10-13 July, p. 15. Mirmiran, M., W. Witting and D.F. Swaab - Effects of aging on circadian rhythms of rats. 10th European Winter Conference on Brain Research, 3-10 March, Les Arcs, France. Raadsheer, F.C., A.A. Sluiter, R. Ravid, F.J.H. Tilders and D.F. Swaab - Human hypothalamic corticotropin releasing hormone (CRH) neurons in relation to aging, Alzheimer's disease and depression. Abstracts 'Retraite MW-dwarsverband Gerontologie', Egmond aan Zee, 25-26 October. Ravid, R. and D.F. Swaab - Brain Bank: A clinico-pathological link in aging and dementia research. Abstracts 'Retraite MW-dwarsverband Gerontologie', Egmond aan Zee, 25-26 October. Ravid, R. and D.F. Swaab - Brain Bank: A clinico-pathological link in aging and dementia research. 2nd International Conference on Alzheimer's Disease & Related Disorders, Toronto, 15-20 July. Neurobiology of Aging 11, 275-276 (Abstr. 95). Ravid, R. and D.F. Swaab - Brain Bank: A clinico-pathological link in aging and dementia research. Abstracts XIth international congress of neuropathology, Kyoto, Japan, September 2-8, p.221. Ravid, R. and D.F. Swaab - Immunocytochemical demonstration of vasopressin binding in rat kidney (letter to the editor). J. Histochem. Cytochem. 38, 1693. Ravid, R., D.F. Swaab, J. v. Heerikhuize, W. Kamphorst, H.G. Haigler, H.A. Ghanbari, B.E. Miller - Temporalfrontal changes in Alzheimer's disease associated proteins: a biochemical study. 2nd International Conference on Alzheimer's Disease & Related Disorders, Toronto, 15-20 July. Neurobiology of Aging 11, 332 (Abstr. 329), 1990. Ravid, R., D.F. Swaab, J. v. Heerikhuize, W. Kamphorst, H.G. Haigler, H.A. Ghanbari, B.E. Miller - Temporal versus frontal changes in Alzheimer's disease associated proteins: a biochemical study. Abstracts XIth international congress of neuropathology, Kyoto, Japan, September 2-8, p.166. Swaab, D.F. - Book review: Research and Perspectives in Alzheimer's Disease. Neuronal Grafting and Alzheimer's Disease, F.H. Gage, A. Privat and Y. Christen (eds.), Springer Verlag, Berlin/Heidelberg etc. Tijdschr. Geront. Geriat. 21: 142, 1990. Swaab, D.F., H.P.H. Kremer, R. Ravid, E. Goudsmit, J.A.P. van de Nes, K. Iqbal and I. Grundke-Iqbal - Hypothalamic cytoskeletal alterations during aging and in Alzheimer's disease. Abstracts XIth International Congress of Neuropathology, Kyoto, Japan, 2-8 September, p.164. Swaab, D.F. - Book review: Neuroendocrine Perspectives, Vol. 7. E.E. Müller and R.M. MacLeod (eds.) Springer Verlag, Berlin/Heidelberg etc., J. Neurol. Sci. 96, no. 1, April 1990, 128. Swaab, D.F., E. Goudsmit and H.P.H. Kremer - Neuroendocrine changes in aging and dementia. 3rd International Brain Workshop on Neurodevelopment, Aging and Cognition, Dubrovnik, 7-13 May. Swaab, D.F., H.P.H. Kremer, R. Ravid, E. Goudsmit, J. van de Nes, K. Iqbal and I. Grundke-Iqbal - Cytoskeletal alterations in the hypothalamus during aging and in Alzheimer's disease. 2nd International Conference on Alzheimer's disease & Related Disorders, 15-20 July, Toronto, Canada. Neurobiology of Aging 11, 277 (Abstr. 102). Swaab, D.F. and M. Mirmiran - Neuroanatomical changes in rat and human SCN in relation to age. 10th European Winter Conference on Brain Research, 3-10 March, Les Arcs, France Swaab, D.F. - Book review: Mullaart, E. - Damage and Repair in Relation to Aging. Thesis University of Leiden. Meppel: Krips Repro, 1989, 177 pp. Tijdschr. Gerontol. Geriatr. 21 Troost, D., J.M.B.V. De Jong and D.F. Swaab - Neurofilamentveranderingen in de cerebrale cortex bij patiënten met amytrofische laterale sclerose. Ned. Tijdschr. Geneesk. 134, 1824. Van de Nes, J.A.P., D.F. Swaab, P. Eikelboom, W. Kamphorst and R. Ravid - How useful is the antibody Alz-50 for the diagnosis of Alzheimer's disease. Abstracts 'Retraite MW-dwarsverband Gerontologie', Egmond aan Zee, 25-26 October. Van Eerdenburg, F.J.C.M., P. Poot, G.J. Molenaar, F.W. van Leeuwen and D.F. Swaab - A vasopressin and oxytocin containing nucleus in the pig hypothalamus that shows increase in neuron number during puberty. Proceedings of the 3rd International Vasopressin Conference, Montpellier, France, 5-10 August, Abstract A37. Van Eerdenburg, F.J.C.M., P. Poot, G.J. Molenaar, F.W. van Leeuwen and D.F. Swaab - A vasopressin and oxytocin containing nucleus in the pig hypothalamus that shows increase in neuron number during puberty. Abstracts of the 20th Meeting of the Society for Neuroscience, St. Louis, Vol. 16, in press. Van Gool, W.A., P.A. Bolhuis, R. Ravid, H. van Crevel, D.F. Swaab - Studying the value of a diagnostic test for Alzheimer's disease (AD) on cerebrospinal fluid (CSF) samples. AAN Scientific Program. Van Zwieten, E.J., W.T. Kos, R. Ravid and D.F. Swaab - Decreased number of vasopressin expressing neurons in the medial amygdala and locus coeruleus of the senescent rat. Abstracts 'Retraite MW-dwarsverband 107

Gerontologie', Egmond aan Zee, 25-26 October. Van Zwieten, E.J., Ravid R., Swaab D.F. - Postmortem effects on vasopressin producing neurons in the suprachiasmatic nucleus of the Wistar rat. Eur. J. Neurosci. Suppl. 2, 208. 1991 Chouham, S., F.J.C.M. van Eerdenburg, J.F. Axelson, D.F. Swaab and F.W. Van Leeuwen -The distribution of estrogen receptors in the pig hypothalamus, Third IBRO World Congress of Neuroscience, August 4-9, 1991, Montreal, Canada, P. 33.44, p. 232 Goudsmit, E., Hofman, M.A., Fliers, E. and Swaab, D.F. - Supraoptic and paraventricular nuclei of human hypothalamus in relation to sex, age and Alzheimer's disease. Parkinson/Alzheimer Digest 3, 19-21, 1991. Goudsmit, E., A. Neijmeijer-Leloux and D.F. Swaab - The human hypothalamo-neurohypophyseal system in relation to development, aging and Alzheimer's disease. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 28-29. Goudsmit, E. and D.F. Swaab - Vasopressin and oxytocin cell numbers in the human hypothalamus during aging and in Alzheimer's disease. Society for Neuroscience Abstracts, Vol. 17, no. 308.6, p. 771, 1991. Hofman, M.A. and D.F. Swaab - Seasonal changes in the morphology of the human hypothalamus. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 30-31. Hofman, M.A. and D.F. Swaab - Effects of light and aging on the human suprachiasmatic nucleus, International Symposium on New Functional Aspects of the Suprachiasmatic Nucleus of the Hypothalamus, October 27-31, 1991, Osaka, Japan, p. 41. Lucassen, P.J., D.F. Swaab, R. Ravid and N.K. Gonatas - Changes in Golgi-apparatus in human supraoptic and paraventricular nucleus with age and Alzheimer's disease, Third IBRO World Congress of Neuroscience, August 4-9, 1991, Montreal, Canada, P. 11.20, p. 90. Lucassen, P.J., D.F. Swaab, R. Ravid and N.K, Gonatas - Changes in Golgi-apparatus in human supraoptic and paraventricular nucleus with age and Alzheimer's disease. In: Abstracts van de NWO Retraite Gerontologie en Geriatrie, "Plasticiteit en veroudering: Use it or lose it. Egmond aan Zee, The Netherlands, October 24-25. Lucassen, P.J., D.F. Swaab, R. Ravid and N.K. Gonatas - Changes in Golgi-apparatus in human supraoptic and paraventricular nucleus with age and Alzheimer's disease. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 100. Mijnster, M.J., E.J. Van Zwieten and D.F. Swaab - Identification of possible synaptic contacts between vasopressin fibers and locus coeruleus neurons in the human brain. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 104-105. Neijmeijer-Leloux, A., E. Goudsmit and D.F. Swaab - Fetal development of vasopressin and oxytocin neurons in the human hypothalamus. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 110-111. Panayotacopoulou, M.T. and D.F. Swaab - Development of tyrosine-hydroxylase immunoreactive (TH-IR) neurons in the human paraventricular and supraoptic nuclei. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 112. Raadsheer, F.C., A.A. Sluiter, R. Ravid, F.J.H. Tilders and D.F. Swaab - Colocalization of corticotropin releasing hormone (CRH) and vasopressin (AVP) in human paraventricular nucleus (PVN) neurons, Third IBRO World Congress of Neuroscience, August 4-9, 1991, Montreal, Canada, P. 33.33, p. 230. Raadsheer, F.C., A.A. Sluiter, R. Ravid, F.J.H. Tilders and D.F. Swaab - Human hypothalamic corticotropin releasing hormone (CRH) neurons in relation to aging, Alzheimer's disease and depression. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, 113-114. Ravid, R., J.J. van Heerikhuize, D.F. Swaab, W. Kamphorst and H.A. Ghanbari -Temporo-frontal differences in alzheimer's disease associated protein - a biochemical study, Society for Neuroscience, New Orleans, USA, vol. 17, no. 147.11, p. 352. Ravid, R., D.F. Swaab and E.J. Van Zwieten - Brain Banking and the human hypothalamus - factors to match for. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 62-64. Romijn, H.J., A.W.J.W. Janszen, M.A. Hofman and D.F. Swaab - Perinatal hypoxic-ischemic encephalopathy and GABA-IR neurons. 12th EKN meeting, Neurochemical and neuropharmaological aspects of epilepsy, Antwerp, Belgium, 22 November. Swaab, D.F. - Book review of Neuroendocrinology: New Frontiers, Gupta, D., Wollmann, H.A. and Ranke, M.B. (Eds.) Neuroendocrinology Letters, 13, p. 392 (1991). Swaab, D.F. - Book review of Stress and the Aging Brain. Integrative Mechanisms. G. Nappi, A.R. Genazzani, E. Martignoni, F. Petraglia (Eds.) Aging Series vo. 37. New York: Raven Press 1990. Tijdschr. Gerontol. Geriatr. 1991; 22, p. 670, P. 264.1. Swaab, D.F. - The human hypothalamus in health and disease. Abstracts Rheinhardsbrunn Symposium, 108

Leipzig, Germany, 24-29 March, p.92. Swaab, D.F. and M.A. Hofman - The human suprachiasmatic nucleus (SCN); differences in relation to sexual orientation and season, Society for Neuroscience Abstracts, Vol. 17, no. 264.1, p.670, 1991. Swaab, D.F. and M.A. Hofman - Differentiation of the human hypothalamus in relation to gender and sexual orientation. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 75-76. Taphoorn, M.J.B., F.J. Snoek, E. van Someren, R.L.M. Strijers, D.F. Swaab, F. Visscher, L. de Waal, C.H. Polman - Analysis of chronic fatigue, excessive daytime sleepiness and circadian rhythm in patients with multiple sclerosis. Anton M.L. Coenen (Ed.) Dutch Society for Sleep-Wake Research, Sleep-Wake Research in the Netherlands, Abstracts 1991, p. 113-114. Van de Nes, J.A.P., D.F. Swaab, P. Eikelenboom, W. Kamphorst and R. Ravid - The distribution of Alz-50 immunoreactivity in the hypothalamus of Alzheimer patients and controls. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 116-117. Van de Nes, J.A.P., W. Kamphorst, R. Ravid and D.F. Swaab - Cytoskeletal changes in the hypothalamus of Alzheimer patients: do they lead to cell death, and are they induced by plaques? In: Abstracts of NWO retraite Gerontologie en Geriatrie "Plasticiteit en veroudering: Use it or lose it. Egmond aan Zee, The Netherlands, October 24-25, 1991. Van der Woude, P.F., Wierda, M., E. Goudsmit and D.F. Swaab - Oxytocin and vasopressin cell numbers in the human paraventricular nucleus with aging and in Alzheimer's disease. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 118-119. Van Eerdenburg, F.J.C.M. and D.F. Swaab - Postnatal development of a new, sexually dimorphic, vasopressin and oxytocin containing nucleus in the hypothalamus of the pig. 17th International Summer School of Brain Research, August 26-30, 1991, Amsterdam, The Netherlands, p. 120. Van Eerdenburg, F.J.C.M., S. Chouham, J.F. Axelson, D.F. Swaab and F.W. van Leeuwen - The Distribution of estrogen receptors in the pig hypothalamus. Society for Neuroscience Abstracts, Vol. 17, #172.12, p. 419, 1991. Van Someren, E.J.W., D.F. Swaab, M. Mirmiran, W.A. van Gool, J.D. Speelman and B.F.M. Vonk - A new method for long-term ambulatory tremor registration, WF-SRS in Sleep Research 20A, Cannes, 21-25 September. pp. 521. 1992 Hoogendijk, W.J.G., Pool, Ch., Troost, D. and Swaab, D.F. - Parkinson's disease and amyotrophic lateral sclerosis. 7th International Catecholamine Symposium, June 23-26, 1992, Amsterdam, The Netherlands, p. 141, 1992. Hoogendijk, W.J.G., Pool, Ch., Troost, D. and Swaab, D.F. - The locus coeruleus (LC) in Alzheimer's disease (AD), Parkinson's disease (PD), and amyotrophic lateral sclerosis (ALS), Neurobiology of Aging 13, suppl. 1, abstract no. 193, 1992. Hoogendijk, W.J.G., Pool, Ch., Troost, D. and Swaab, D.F. - The locus coeruleus in Alzheimer's disease, Parkinson's disease and amyotrophic lateral sclerosis. 7th International Catecholamine Symposium, Amsterdam, June 22-26. Kudo, T., Ravid, R., Swaab, D.F. and Grundke-Iqbal, I. - Measurement of ubiquitin immunoreactivity in cerebrospinal fluid (CSF) of Alzheimer's disease and control patients. Neurobiology of Aging 13, suppl. 1, abstract no. 114. Lucassen, P.J., Swaab, D.F., Ravid, R. and Gonatas, N.K. - Vasopressin and oxytocin in aging and Alzheimer's disease. In: Progress Report of the Netherlands Brain Bank 1991, pp. 57-58. Lucassen, P.J., Swaab, D.F., Ravid, R. and Gonatas, N.K. - Changes in Golgi-apparatus in human supraoptic and paraventricular nucleus with age and Alzheimer's disease. Neurobiology of Aging 13, suppl. 1, abstract no. 197. Mirmiran, M., Hagebeuk, E., Van Someren, E., Witting, W., Swaab, D.F., Van Gool, W.A. and Hofman, M.A. - Circadian Rhythms disturbances in Alzheimer's disease. Sleep-Wake research in The Netherlands, vol. 3, 1992, pp. 121-123, Dutch Society for Sleep-Wake Research, Coenen, A.M.L. (Ed.) Panayotacopoulou, M.T., Raadsheer, F.C. and Swaab, D.F. - Colocalization of tyrosine hydroxylase with oxytocin or vasopressin in neurons of the human paraventricular and supraoptic nuclei. 7th International Catecholamine Symposium, Amsterdam, June 22-26, p. 246, 1992. Panayotacopoulou, M.T. and Swaab, D.F. - Development of tyrosine hydroxylase immunoreactive neurons in the human paraventricular and supraoptic nucleus. IBRO workshop "Mechanisms of neuronal plasticity", University of Padras, Greece, 8 October 1992. Ravid, R., Van Zwieten, E.J., Swaab, D.F. and Kamphorst, W. - Cerebrospinal fluid ph is not influenced by postmortem interval in Alzheimer's and controls. Neurobiology of Aging 13, suppl. 1, abstract no. 129, 1992. Swaab, D.F. - Book review: G. Krämer, De Ziekte van Alzheimer, oorzaken, symptomen, onderzoek en 109

behandeling (Alzheimer's disease, causes, symptoms, research and treatment). De Driehoek, Amsterdam, 96 pp., 1991, Tijdschrift voor Gerontologie en Geriatrie, 23, 167, 1992. Swaab, D.F. - Book review: I. Hindmarch, H. Hippius and G. Wilcock (Eds.), Dementia: Molecules, Methods and Measures. John Wiley & Sons, Chichester, U.K., 208 pp., 1991. Tijdschrift voor Gerontologie en Geriatrie, 2, 79, 1992. Swaab, D.F. and Hofman, M.A. - Sexual differentiation, aging and dementia and the human hypothalamus. Int. J. of Developmental Neuroscience. 9th International meeting of the international society for developmental neuroscience. June 14-18, La Grande Motte, France, #31, p 45, 1992. Swaab, D.F. - Plastic changes in the human hypothalamus. Publication for proceedings of Decade of the Brain, 10 December. Swaab, D.F., Grundke-Iqbal, I., Iqbal, K., Lucassen, P.J., Raadsheer, F.C., Ravid, R and Van de Nes, J.A.P. - The human hypothalamus and Alzheimer symptoms. Neurobiology of Aging 13, suppl. 1, abstract no. 171, 1992. Swaab, D.F. - Histochemistry of the human hypothalamus in development and aging. Histochem. J. 24: 474 (1992). Swaab, D.F., Hofman, M.A., Lucassen, P.J., Purba, J.S. and Raadsheer,F.C. - Neurohypophyseal peptides in the human hypothalamus in relation to development, sexual differentiation, aging and disease. Satellite Symposium of the N.I.C.E. '92: The Neurohypophysial Peptide Systems, Spa-Liège, Belgium, 6-11 September 1992, p. 46. Swaab, D.F., Hofman, M.A. and Mirmiran, M. - The human suprachiasmatic nucleus in relation to aging and dementia. Meeting of the Dutch Association for Sleep/ Wake Research, Amsterdam, 16 October. Swaab, D.F. - Neurobiologische aspecten van de ziekte van Alzheimer. Neurobiologisch Symposium Het Brein in Stukken, Amsterdam, 11 November. Swaab, D.F. - De ziekte van Alzheimer. Neurobiologisch Symposium Het Brein in Stukken, Amsterdam, 11 November. Swaab, D.F., Gooren, L.J.G. and Hofman, M.A. - Sexual dimorphism of hypothalamic nuclei: neuroanatomical and clinical aspects. New Trends in Psychoneuroendocrinological approach of sexual behavior, Liège, Belgium, 9 October. BCNP XVth Annual Forum Joint Meeting. Swaab, D.F., Hofman, M.A. and Mirmiran, M. - The human suprachiasmatic nucleus in relation to aging and dementia. Sleep-Wake research in the Netherlands, vol. 3, 1992, pp. 161-162, Dutch Society for Sleep-Wake Research, Coenen, A.M.L. (Ed.). Swaab, D.F. - Plastic changes in the human hypothalamus. Proceedings of the 'Decade of the Brain' Conference, Amsterdam, December 1992, p. 33. Swaab, D.F. - Neuropeptiden in de hypothalamus van de mens. Verslag Afd. Nat. 101(9), 1992. Taphoorn, M.J.B., Snoek, F.J., Van Someren, E., Strijers, R.L.M., Swaab, D.F., Visscher, F., De Waal, L. and Polman, C.H. - Sleep disturbances and circadian rhythms in multile sclerosis patients. Sleep-Wake research in the Netherlands, vol. 3, 1992, pp. 165-168, Dutch Society for Sleep-Wake Research, Coenen, A.M.L. (Ed.). Taphoorn, M.J.B., Snoek, F.J., Van Someren, E., Strijers, R.L.M., Swaab, D.F., Visscher, F., De Waal, L. and Polman, C.H. - The circadian rhythm and the multiple sleep latency test in Multiple Sclerosis patients. J. Neurol. 239, Suppl. 2, p. 75. Van der Post, J.A.M., van Buul, E.J.A., van Boxtel, C.E.A., Pesman, G., Steegers, E.A.P., Swaab, D.F. and Boer, K. - Effects of dietary sodium restriction on vasopressin and oxytocin plasma levels in normal pregnancy. ISSHP Meeting, Buenos Aires, Argentina, 8-12 November. Van der Post, J.A.M., Konijnenberg, A., Boer, K., Schaap, M.C.L., van Boxtel, C.E.A., Sturk, A., Boer, G.J. and Swaab, D.F. - Gestational hypertension is not associated with altered platelet vasopressin binding and cytosolic CA2+ concentration. ISSHP Meeting, Buenos Aires, Argentina, 8-12 November. Van de Nes, J.A.P., Kamphorst, W., Ravid, R. and Swaab, D.F. - Alzheimer's disease: are cytoskeletal changes induced by plaques and do they lead to cell death? Neurobiology of Aging 13, suppl. 1, abstract no. 138, 1992. Van de Nes, J.A.P., Kamphorst, W., Ravid, R. and Swaab, D.F. - Plaques, cytoskeletal changes and cell death in the Alzheimer hypothalamus. Proceedings 22nd Annual Meeting Society for Neuroscience, Anaheim, USA, p. 734. Van Zwieten, E.J., Ravid, R. and Swaab, D.F. - Vasopressin innervation of the locus coeruleus and nucleus parabrachialis in aging and Alzheimer's disease. Neurobiology of Aging 13, suppl. 1, abstract no. 179, 1992. Van Someren, E.J.W., Van Gool, W.A., Vonk, B.F.M., Mirmiran, M., Speelman, J.D., Bosch, D.A. and Swaab, D.F. - Ambulatory movement and tremor registration during sleeping and waking. Sleep-Wake research in the Netherlands, vol. 3, 1992, pp. 157-158, Dutch Society for Sleep-Wake Research, Coenen, A.M.L. (Ed.). Van Someren, E.J.W., Van Gool, W.A., Vonk, B.F.M., Mirmiran, M., Speelman, J.D., Bosch, D.A. and Swaab, D.F. - A new method for long-term ambulatory movement and tremor registration. J. Interdiscipl. Cycle Res. 23: 183-184, 1992. 110

1993 Fliers, E., Wiersinga, W.M., Van Zwieten, E.J. and Swaab, D.F. - TRH cells and fibers in the human hypothalamus. 75th Annual Meeting Endocrine Society, Las Vegas, USA, 1993, p. 475. Panayotacopoulou, M.T., F.C. Raadsheer and D.F. Swaab - Expression of tyrosine hydroxylase in neurons of the paraventricular and supraoptic nucleus of the human neontae: primary developmental phenomenon or induced by perinatal asphyxia? First International Congress on Hormones, Brain and Neuropsychopharmacology, Rhodes, Greece, September 13-17, 1993. Swaab, D.F. (book review for Tijdschrift voor Gerontology en Geriatrie, vol. 24, p. 143) L. Parker, L. Prilipko and Y. Christen (Eds.) Free Radicals in the Brain. Aging, Neurological and Mental Disorders, 1993, Berlin, Springer Verlag. Swaab, D.F., Lucassen, P.J., Raadsheer, F.C. and Salehi, A. - The relation between functional use and structural integrity in neuronal nets: wear and tear versus use it or lose it. Sixth Congress of the International Psychogeriatric Association (IPA), Berlin, Germany, September 5-10, 1993. Swaab, D.F. and Hofman, M.A. - Sexual differentiation of the human hypothalamus. 32nd congress of the international union of physiological sciences. 1-6 August 1993, p. 35, # 21.1/0. Swaab, D.F. Hofman, M.A. and Zhou, J.N. - The human suprachiasmatic nucleus (SCN) in a periodic environment. Fifth Sapporo Symposium on Biological Rhythms, Sapporo, Japan, 25-28 August 1993, p. 45. Van Someren, E.J.W., Swaab, D.F., Mirmiran, M., Van Gool, W.A., Speelman, J.D. and Vonk, B.F.M. - A new device for concurrent long-term ambulatory movement and tremor registration. Sleep Research 22, 611 (1993). Van Someren, E.J.W., Hagebeuk, E.E.O., Swaab, D.F., Mirmiran, M., Scheltens, Ph., Schrijver, Th.L., Kolder, R.M.M., De Rooij, S.E.J.A., Walstra, G.J.M., Jonker, C. and Pot, A.M. - Circadian rest-activity rhythm disturbances in Alzheimer's disease. Sleep Research 22, 637 (1993). Van Eerdenburg, F.J.C.M. and Swaab, D.F. - Postnatal development and sexual differentiation of pig hypothalamic nuclei. International Conference on Hormones, Brain and Behaviour. Tours, France, August 24-27, 1993, p. 55-56. 1994 De Vos, R.A.I., Jansen, E.N.H., Stam, F.C., Ravid, R. and Swaab, D.F. - Clinicopathological findings in 22 cases of "Lewy body disease". P32-12, XIIth International Congress of Neuropathology, Brain Pathology 4: 533, 1994. Gabreëls, B.A.Th.F., Swaab, D.F. and Van Leeuwen, F.W. - Coincidence of the absence of neuroendocrine polypeptide 7B2 and vasopressin in the hypothalamus of some Prader-(Labhart)-Willi patients. Eur. J. Endocrinol. 130(2): 17, abstract S01.08, 1994. Kamphorst, W., Stam, F.C., Ravid, R. and Swaab, D.F. - Neuropathological scores of Alzheimer changes. Neurobiology of Aging 15, suppl. 1, abstract no. 453, 1994. Noppen, N.W.A.M., Fliers, E., Wiersinga, W.M., Visser, T.J. and Swaab, D.F. - Thyrotropin-releasing hormone (TRH)-containing cells and fibers in the human hypothalamus. Eur. J. Endocrinol. 130(2): 16, abstract S01.05, 1994. Ravid, R., Swaab, D.F., Kamphorst, W., and Stam, F.C. - The way to ideal brain banking in Alzheimer's disease is paved with matching factors. Neurobiology of Aging 15, suppl. 1, abstract no. 590, 1994. Ravid, R. and Swaab, D.F. - The way to ideal brain banking in paved with matching factors. W20-2, XIIth International Congress of Neuropathology, Brain Pathology 4: 368, 1994. Salehi, A., Van de Nes, J.A.P., Lucassen, P.J., Hofman, M.A., Gonatas, N.K. and Swaab, D.F. - Relation between neuronal activity and cytoskeletal changes in Alzheimer's disease. International Workshop on the Borderland between Normal and Pathological Mental Aging. Amsterdam, The Netherlands, June 5-8, abstract P10, 1994. Swaab, D.F. Book review of "Alzheimer Disease" (Robert D. Terry, Robert Katzman and Katherine L. Blick, eds.) New York, Raven Press, 1994, Tijdschrift Gerontol. Geriatr. 1994, 25, 183. Swaab, D.F. - Sexuele differentiatie van de hersenen van de mens. Symposium Humane Ethologie: voorgeprogrammeerdheid en flexibiliteit in de vroege gedragsontwikkeling van de mens. Utrecht, 22 January 1994. Swaab, D.F., Raadsheer F.C., Van de Nes, J.A.P., Salehi, A. and Ravid, R. - Lack of relationship between Alz- 50 staining, -A4 accumulation and neuronal activity in the human hypothalamus of Alzheimer patients. Neurobiology of Aging 15, suppl. 1, abstract no. 571, 1994. Swaab, D.F. - Sexual differentiation of the human hypothalamus. Abstracts of the 17th Annual Meeting of the European Neuroscience Association, Vienna, Austria, September 4-8, abstract no. 72.05, 1994. Swaab, D.F. - Brain changes in Alzheimer's disease: age- or disease-specific? International Workshop on the Borderland between Normal and Pathological Mental Aging. Amsterdam, The Netherlands, June 5-8, p. 6, 111

1994. Swaab, D.F. - Aging of the human hypothalamus. Symposium on Fonctions endocrines et vieillissement/endocrine functions and ageing. P. 6, Paris, France, 5-6 May 1994. Tilders, F.J.H., Schmidt, E.D., Raadsheer, F.C. and Swaab, D.F. - Stress-induced plasticity of hypothalamic CRH neurons. First World Congress on Stress, Bethesda MD, USA, October 2-7, 1994. Tilders, F.J.H., Schmidt, E.D., Van Dijken, H.H., Mos, J., De Goeij, D.C.E. and Swaab, D.F. - Adaptive changes in hypothalamic CRH-neurons in experimental animals and man. Am. College of Neuropsychopharmacology. Puerto Rico, Dec. 12-16, 1994. Van Someren, E.J.W., E.E.O. Hagebeuk, M. Mirmiran and D.F. Swaab - The involvement of activity level, dementia severity, sleep disruption and environmental light in circadian rest-activity rhythm disturbances in Alzheimer's disease. EUROSLEEP 94.!2th Congress of the European Sleep Research Society, Florence, Italy, May 22-27, 1994. 1995 Dean, A.F., Watkins, P.J., Morley, S. and Swaab, D.F. - Hypothalamic and brainstem neuropathology in a 49- year old man with DIDMOAD syndrome. British Neuropathological Society. Erkut, Z.A., Hofman, M.A., Ravid, R., Swaab, D.F. - Hyperactivity of corticotropin-releasing hormone (CRH) neurons in multiple sclerosis (MS) patients. ENA, Amsterdam, 3-7 September 1995, #49.21, p. 17. Erkut, Z.A., Hofman, M.A., Ravid, R. and Swaab, D.F. - Increased activity of corticotropin-releasing hormone (CRH) neurons in multiple sclerosis (MS) patients. Satellite Symposium "Neurobiology of Stress". 8-9 Sept. 1995, Haren, p. 18. Guldenaar, S.E.F. and Swaab, D.F. - Oxytocin mrna in the human paraventricular nucleus in AIDS. In: R. Ivell and J.A. Russell (Eds.) Oxytocin: Cellular and Molecular Approaches in Medicine and Research. Advances in Experimental Medicine and Biology, Vol. 395, Plenum Press, New York, pp. 91. Guldenaar, S.E.F., Purba, J.S., Boerma, D. and Swaab, D.F. - Oxytocin and corticotropin-releasing hormone in the human paraventricular nucleus in AIDS. 12th Int. Symposium Neurosecretion, Kiel, Germany, 1995. Hofman, M.A. and Swaab, D.F. - Diurnal and seasonal rhythms in the suprachiasmatic nucleus of humans. Biological Rhythm Research 26, no. 113, p. 401, 1995. Hoogendijk, W.J.G., Swaab, D.F. and Eikelenboom, P. - Depression and the noradrenergic system in Alzheimer's disease. Abstracts of the III European Congress of Gerontology, 30 August - 2 September 1995. #0605 Kamphorst, W., Ravid, R., Swaab, D.F. and Van Zwieten, E.J. - Alzheimer scores of Netherlands Brain Bank Cerebra. J. Neuropathol. Exp. Neurol. 54 (supplement): 83S, 1995. Lucassen, P.J., Raadsheer, F.C., Purba, J.S., Guldenaar, S.E.F., Tilders, F.J.H., and Swaab, D.F. - Corticotropin-releasing hormone (CRH) and vasopressin (VP) in the human hypothalamus; activity changes with aging, Alzheimer's disease and depression. Symposium on stress and aging of the IIIrd European Congress of Gerontology, Amsterdam, 30 August - 2 September 1995. Lucassen, P.J., Chung, W.J.C. and Swaab, D.F. - Distribution of DNA damage in Alzheimer brain as detected with the apoptosis marker technique in situ end labeling of fragmented DNA. ENA meeting, Amsterdam, 3-7 September 1995. Lucassen, P.J., Raadsheer, F.C., Guldenaar, S.E.F., Tilders, F.J.H., and Swaab, D.F. - In situ hybridization for CRH and AVP-mRNA in the human hypothalamus; changes with aging, Alzheimer's disease and depression. Abstract for the 7th Meeting of the European Neuroendocrine Association. Tel Aviv, Israel, pp. 31. Panayotacopoulou, M.T., Goudsmit, E., Van Heerikhuize, J.J. and Swaab, D.F. - Simultaneous detection of tyrosine-hydroxylase immunoreactivity and vasopressin mrna in neurons of the human paraventricular and supraoptic nucleus. ENA, Amsterdam, 3-7 September 1995. Ravid, R. and Swaab, D.F. - Brain banking in Alzheimer's disease: pitfalls and potentials. Neuropathology and Applied Neurobiology 21, 18-19, 1995. Ravid, R., Swaab, D.F. and Van Zwieten, E.J. - De Nederlandse Hersenbank: 1985-1995 (The Netherlands Brain Bank: 1985-1995). Publieksdag (Public lectures day at the) RAI, 8 September 1995. Ravid, R., Swaab, D.F., Cruz-Sanchez, F.F. - Brain banks: a clinico-pathological link in aging and dementia research. Satellite Symposium of 4th IBRO World Congress of Neuroscience. pp. 522. Ravid, R., Swaab, D.F., Kamphorst, W. and Van Zwieten, E.J. - A golden standard protocol for the brain banking society? The Amsterdam experience. J. Neuropathol. Exp. Neurol. 54 (supplement): 25S-26S. Salehi, A., Verhaagen, J., Kaplan, D. and Swaab, D.F. - Expression of high affinity neurotrophin receptors (TRK A, B and C) in the nucleus basalis of Meynert of human brain. Keystone Symposia, The Molecular and Cellular Basis of Human Neurodegenerative Disease. Breckenridge, USA, April 3-9, 1995. Salehi, A., Verhaagen, J. and Swaab, D.F. - Differential reduction in high affinity neurotrophin receptors in the nucleus basalis of Meynert of Alzheimer patients. ENA, Amsterdam, 3-7 September 1995 112

Swaab, D.F., Zhou, J.N. and Hofman, M.A. - The neurobiology and neuropathology of the human hypothalamus. Symposium in Kiel, Germany, 1995, p. 48 Swaab, D.F. Sexe en Brein. Boekbespreking voor BioNieuws nr. 3, p. 6, 1995, van "Het Seksuele Brein" van Simon LeVay, en "Myths of Gender: Biological Theories about Women and Men" van Anne Fausto-Sterling. Swaab, D.F., Zhou, J.N. and Hofman, M.A. - Sexual differentiation of the human hypothalamus. The Biological Basis of Sexual Orientation and Sex - Typical Behavior, Minot, USA, 1995, p. 72 Swaab, D.F., Purba, J.S. and Hofman, M.A. - The hypothalamic paraventricular nucleus and its oxytocin neurons (putative satiety cells) are affected in Prader-Willi syndrome. 2 nd Prader-Willi Conference, Oslo, Norway, June 1995, abstract # 6 Swaab, D.F., Zhou, J.N. and Hofman, M.A. - Sexual differentiation of the human hypothalamus. Int. Symposium on Sex differentiation: clinical and biological aspects. Cambridge, England, 1-3 July, 1995, abstract # 14, p. 18. Swaab, D.F., Zhou, J.N. and Hofman, M.A. - The human suprachiasmatic nucleus (SCN) in development, sexual differentiation and aging. Abstract for the 19th Summer School of Brain Research. Amsterdam, 28-31 August 1995, pp. 74-75. Swaab, D.F., Hofman, M.A., and Zhou, J.N. - Brain, gender and sexual orientation. Abstract for the 7th Meeting of the European Neuroendocrine Association. Tel Aviv, Israel, p. 29. Swaab, D.F., Zhou, J.N. and Hofman, M.A. - Biological rhythms and the human hypothalamus. Abstract for the 7th Meeting of the European Neuroendocrine Association. Tel Aviv, Israel, p. 63. Swaab, D.F., Zhou, J.N., Hofman, M.A. - Biological clock in the suprachiasmatic nucleus. Satellite Symposium of 4th IBRO World Congress of Neuroscience. Swaab, D.F., Hofman, M.A., Zhou, J.N. - Sexual differentiation of the human hypothalamus. Satellite Symposium of 4th IBRO World Congress of Neuroscience. p. 36. Swaab, D.F., Lucassen, P.J., Salehi, A., Guldenaar, S.E.F. - Immunocytochemistry and in situ hybridization of peptides as a measure of activity in the human brain. Brain Bank Meeting. ENA, RAI, Amsterdam, 3 September 1995, p. 6 Swaab, D.F., Zhou, J.N., Hofman, M.A. - The neurobiology and neuropathology of the human hypothalamus. Proceedings of the 12th International Symposium on Neurosecretion 1995. The Peptidergic Neuron, p. 48, 1995, Kiel, Germany. Swaab, D.F., Zhou, J.N. and Hofman, M.A. - The human suprachiasmatic nucleus (SCN) in development, sexual differentiation and aging. Abstracts 19th International Summer School of Brain Research, p. 73-74. Timmers, H.J.L.M., Swaab, D.F., Van de Nes, J.A.P. and Kremer, H.P.H. - Somatostatin 1-12 immunoreactivity is decreased in the hypothalamic lateral tuberal nucleus of Huntington's disease patients. 16th International meeting of the world federation of neurology research group on Huntington disease. July 15-18, 1995, Leuven, Belgium. Van Someren, E.J.W., Kessler, A., Mirmiran, M. and Swaab, D.F. - Indirect bright light affects circadian restactivity rhythm disturbances of demented patients. "Lux" Society for Light Treatment and Biological Rhythms, vol. 7, p. 13, 1995. Van Someren, E.J.W., Kessler, A., Mirmiran, M. and Swaab, D.F. - Indirect bright light affects circadian restactivity rhythm disturbances of demented patients. 19th International Summer School of Brain Research, 28-31 August 1995, Amsterdam, pp. 112-113. Zhou, J.N., Hofman, M.A. and Swaab, D.F. - Vasoactive intestinal polypeptide (VIP) in human hypothalamus. ENA, Amsterdam, 3-7 September 1995. Zhou, J.N., Hofman, M.A. and Swaab, D.F. - VIP neurons in the human SCN in relation to development, aging, Alzheimer's disease, gender, and sexual orientation. 19th International Summer School of Brain Research, 28-31 August 1995, Amsterdam, pp. 120-121. 1996 Erkut, Z. and Swaab, D.F. - The effects of multiple sclerosis and corticosteroids on hypothalamic CRH and AVP neurons. Society for Neuroscience 1996, no. 335.17, p. 846. Fliers, E., Wiersinga, W.M. and Swaab, D.F. - De TRH cell in de humane hypothalamus. In: Klinisch relevant schildklieronderzoek in Nederland. Een overzicht, anno 1996. G. Henneman and E.P. Krenning (eds.), p. 6, 1996. Fliers, E., Guldenaar, S.E.F., Veldkamp, B., Bakker, O., Wiersinga, W.M. and Swaab, D.F. - Thyrotropinreleasing hormone gene expression in the human hypothalamus. 10th International Congress of Endocrinology, San Francisco, June 12-15. Gabreëls, B.A.Th.F., Swaab, D.F. and Van Leeuwen, F.W. - 7B2 and PC2 are absent in some Prader-Willi patients that are also unable to process the vasopressin precursor correctly. Society for Neuroscience 1996, no. 460.3. 113

Hoogendijk, W.J.G., Purba, J.S., Raadsheer, F.C., Zhou, J.N., Hofman, M.A. and Swaab, D.F. - The hypothalamus of depressed patients. Association of European Psychiatrists/Royal College of Psychiatrists Meeting. 8 July. European Psychiatry 11, Suppl. 4, 156S. Hoogendijk, W.J.G. - Depression in Parkinson's disease is not accompanied by activation of corticotropinreleasing hormone neurons in the hypothalamic paraventricular nucleus. Proceedings Annual Meeting of the American Psychiatric Association, May 4-9, New York, USA, no. 336 (p. 158), 1996. Hoogendijk, W.J.G., Sommers, I., Eikelenboom, P., Pool, C.W. and Swaab, D.F. - The locus coeruleus in Alzheimer's disease: the relation between cell death and depression. Neurobiology of Aging, 17, no. 470, S117, 1996 Hoogendijk, W.J.G., Purba, J.S., Raadsheer, F.C., Zhou, J.N., Hofman, M.A., and Swaab, D.F. - The hypothalamus of depressed patients. Eur. Psych. 11: 156S, 1996. Hoogendijk, W.J.G., Purba, J.S., Hofman, M.A., De Vos, R.A.I., Jansen-Steur, E.N.H. and Swaab, D.F. - Corticotrophin-releasing hormone (CRH) neurons in the hypothalamic paraventricular nucleus of depressed and non-depressed parkinsonian patients with and without dementia. Eur. Neuropsychopharmacology 6, no. p.2.002, S4-94. Lahr, G., Mayer, A., Pilgrim, C., Swaab, D.F. and Reisert, I. - Sex-specific gene regulation in mammals. Hormonal and genetic disorders in gender-specific brain differentiation. 2nd EU Biomed Meeting, June 29-July 2, 1996, Salamanca, Spain. Lucassen, P.J., Chung, W.J.C. and Swaab, D.F. - Hippocampal DNA damage in Alzheimer brain. Proceedings 40th Oholo Conference on New Frontiers in Stress Research: modulation of brain function, Zichron Ya'akov, Israel, 24-28 March, p. 13. 1996. Mayer, A., Lahr, G., Pilgrim, C., Swaab, D.F. and Reisert, I. - Expression of the testis-determining gene, SRY, in the human brain. Hormonal and genetic disorders in gender-specific brain differentiation.2nd EU Biomed Meeting, June 29-July 2, 1996, Salamanca, Spain Panayotacopoulou, M.T., Van Heerikhuize, J.J., Guldenaar, S.E.F., Swaab, D.F. - Tyrosine-hydroxylase mrna in neurons of the human paraventricular and supraoptic nucleus demonstrated by in situ hybridization. 12th Annual Meeting of the Hellenic Society for Neuroscience 25-27 October 1996. Ravid, R., Swaab, D.F., Van Zwieten, E.J. and Cruz-Sanchez, F.F. - Brain banking - the future options in aging and dementia research. Neurobiology of Aging, 17, no. 477, S119, 1996. Ravid, R. and Swaab, D.F. - Ethical and legal issues in brain banking. Alzheimer s disease international 12th International Conference, p. 35, Jerusalem, Israel, Oct. 8-11, 1996 Salehi, A., Pool. C.W., Gonatas, N.K. and Swaab, D.F. - Decreased protein synthetic ability and the neuropathological hallmarks of Alzheimer's disease are independent phenomena. Neurobiology of Aging, 17, no. 734, S183, 1996. Swaab, D.F., Van de Nes, J.A.P. and Salehi, A. - Hallmarks of Alzheimer's disease are independent phenomena. Neurobiology of Aging, 17, no. 804, S200, 1996. Swaab, D.F., Van de Nes, J.A.P. and Salehi, A. - Hallmarks of Alzheimer's disease are independent phenomena. 5th International conference on Alzheimer's disease and related disorders. Fondation IPSEN symposium on Connections, Cognition et Maladie d'alzheimer. Paris, 20 May 1996. Swaab, D.F., Van Someren, E.J.W., Lucassen, P.J. and Salehi, A. - Alzheimer changes in hypothalamic nuclei: their relationship to neuronal activity and clinical symptoms. Fondation IPSEN symposium on Connections, Cognition et Maladie d'alzheimer. Paris, 20 May 1996. Swaab, D.F., Raadsheer, F.C., Lucassen, P.J., Hoogendijk, W.J.G. and Tilders, F.J.H. - The activity of corticotropin releasing hormone (CRH) neurons in the human hypothalamus in relation to aging, Alzheimer's disease and depression. Eur. Psych. 11: 194S, 1996. Swaab, D.F. - Book review of Neurotransmitters in the human brain (Tracey, Paxinos and Stone, Eds.). J. Chem. Neuroanat., vol. 11, p. 79, 1996. Swaab, D.F. - Desirable Biology. Book review of Queer science: the use and abuse of research into homosexuality. Nature, vol. 382: p. 682-683, 1996. Swaab, D.F. - Sexual differentiation of the human hypothalamus. Frontiers in maternal, fetal and neonatal health. Session 7, The developing brain and the origins of behavior. Cornell University, Ithaca, USA, August 9-12, 1996 Swaab, D.F. - Sexual differentiation of the human hypothalamus. 2nd EU Biomed Meeting, June 29-July 2, 1996, Salamanca, Spain Swaab, D.F. - Sexual differentiation of the human hypothalamus. International Academy of Sex Research, p. 74, 1996. 1997 Chung, W.C.J., Carlson, N.R., Swaab, D.F., De Vries, G.J. - Apoptosis in the development of sex differences in 114

the rat brain. Society for Neuroscience 1997, New Orleans, USA, # 139.4, p. 341. Dai, J.P., Swaab, D.F., Van der Vliet, J., Buijs, R.M. - Postmortem tracing in human brain reveals hypothalamic projections of the biological clock. Society for Neuroscience 1997, New Orleans, USA, # 865.8, p. 2224. Dubelaar, E.J.G., Salehi, A., Mulder, M., Gonatas, N.K., Swaab, D.F. - Decreased neuronal activity of nucleus basalis neurons in Alzheimer s disease is APOE dependent. 20th International Summer School of Brain Research, Amsterdam, 25-29 August 1996. p. 107. Fliers, E., Guldenaar, S.E.F., W.M. Wieringa and D.F. Swaab - Decreased thyrotropin-releasing hormone (TRH) gene expression in the paraventricular nucleus of patients with nonthyroidal illness. 24th Annual Meeting of the European Thyroid AssociationG. August 30-September 1, 1997, Munich, Germany. Gabreëls, B.A.Th.F., Swaab, D.F. and Van Leeuwen, F.W. - Concomitant absence of 7B2, convertase PC2 and enzymatically processed vasopressin in the hypothalamus of some Prader-Willi patients: indications for a processing disturbance. 79th annual meeting of the Endocrine Society, 1997. Gabreëls, B.A.Th.F., Swaab, D.F. and Van Leeuwen, F.W. - The vasopressin precursor is not processed in the hypothalamus of Wolfram patients with diabetes insipidus: evidence for the involvement of PC2 and 7B2. 79th annual meeting of the Endocrine Society, 1997. Guldenaar, S.E.F., Unmehopa, U.A., Fliers, E., Swaab, D.F. - Localization of leptin- and leptin-receptor mrna in the human hypothalamus. Endocrine Soc., USA, 1997. Huitinga, I., Van der Cammen, M.J.F., Salm, L., Erkut, Z.A., Van Dam, A.-M., Tilders, F.J.H., Ravid, R. and Swaab, D.F. - Interleukin-immunoreactivity in the human hypothalamus. Society for Neuroscience 1997, New Orleans, USA, #593.27, p. 1513. Huitinga, I., Van der Cammen, M.J.F., Salm. L., Erkut, Z., Van Dam, A.-M., Tilders, F.J.H., Ravid, R., Swaab, D.F. - Interleukin-1 immunoreactive neurons in the human hypothalamus: reduced numbers in multiple sclerosis. Neuroimmunomodulation 4: 200-224, 1997 Huitinga, I., Van der Cammen, M.J.F., Salm, L., Erkut, Z.A., Van Dam, A.M., Tilders, F.J.H., Ravid, R., Swaab, D.F. - Interleukin-1 Immunoreactive neurons in the human hypothalamus: reduced numbers in multiple sclerosis. Neuroimmodulation 4: 219. Lucassen, P.J., De Kloet, E.R., Wouda, J., Holtrop, A., Van Oers, H., and Swaab, D.F. - No increase in DNA damage in the hippocampus of depressed patients. Society for Neuroscience 1997, New Orleans, USA, #698.2, p. 1792. Lucassen, P.J., De Kloet, E.R., Wouda, J., Holtrop, A., Swaab, D.F. - No overall increase in DNA damage in the hippocampus of depressed patients. 20th International Summer School of Brain Research, Amsterdam, 25-29 August 1996. p. 117. Oleana, V.H., Salehi, A., Swaab, D.F. - Increased expression of the apoptosis protein tiar in the hippocampus of Alzheimer s disease patients. 20th International Summer School of Brain Research, Amsterdam, 25-29 August 1996. p. 124. Pilgrim, Ch., Mayer, A., Lahr, G., Swaab, D.F. and Reisert, I. - Sex-specific transcriptional regulators in human brain. Joint meeting of the Polish and German Anatomists, p.27-28. Ravid, R., Swaab, D.F., Kamphorst, W., Van der Valk, P. - Setting up donor programmes for multiple sclerosis via national MS-societies. Biennial conference of the international federation of multiple sclerosis societies. 1997: MS: Creating Awareness & Understanding. Buenos Aires, Argentina, p. 30. Ravid, R., Swaab, D.F., Kamphorst, W., Van der Valk, P., Polman, Ch., Scheltens, Ph., Barkhof, F., Lycklama à Nijeholt, G.J., Van Waesberghe, J.H.T.M. and Van Walderveen, M.A.A. - Brain banking in multiple sclerosis - future options in research. Biennial conference of the international federation of multiple sclerosis societies. 1997: MS: Creating Awareness & Understanding. Buenos Aires, Argentina, p. 30. Ravid, R., Swaab, D.F., Kamphorst, W. - Brain banking in AD, PD and related disorders - The Amsterdam experience. Fourth International Conference. Oholo 41st conference, Progress in Alzheimer s and Parkinson s diseases. Eilat, Israel, May 18-23, p. 26. Salehi, A., Pool, C.W., Verhaagen, J., Swaab, D.F. - Expression of TRK receptors in the nucleus basalis of Meynert and hippocampus of Alzheimer s patients. 20th International Summer School of Brain Research, Amsterdam, 25-29 August 1996. p. 79. Salehi, A., Verhaagen, J., Swaab, D.F. - Expression of trkb receptors in the nucleus basalis of Meynert and hippocampus of Alzheimer patients. Abstracts First Dutch Endo-Neuro Meeting, Doorwerth, p. 36. Swaab, D.F. - Inactivity of neurons in Alzheimer s disease and strategies of reactivation. Oholo 41 st conference, 4th International Conference Progress in Alzheimer s and Parkinson s Diseases. Eilat, Israel, May 18-23, 1997, p. 48. Swaab, D.F., Lucassen, P.J., Salehi, A., Scherder, E.J.A., Van Someren, E.J.W. - Reduced neuronal activity in Alzheimer s disease and strategies of reactivation. 20th International Summer School of Brain Research, Amsterdam, 25-29 August 1997. p. 87. 115

1998 Chung, W.C.J., Lubbers, L.S., De Vries, G.J., Swaab, D.F. - Apoptosis during the development of the sexually dimorphic bed nucleus of the stria terminalis in the human brain. Society for Neuroscience, Los Angeles, 515.11, p. 1297. Dai, J.P., D.F. Swaab, J. Van der Vliet, R.M. Buijs - Postmortem tracing reveals the organization of hypothalamic projections of the suprachiasmatic nucleus in the human brain. J. Comp. Neurol. 400: 87-102. Dai, J.P., Swaab, D.F., Buijs, R.M. - Retinohypothalamic projections in Alzheimer s disease. Neurobiol. Aging 19, #1013, p. S242. De Rijk, R.H., Stam, F.J., Swaab, D.F., Vreugdenhil, E., Datson, N. Roovers, E., De Kloet, E.R., Lucassen, P.J. - Identification of the glucocorticoid receptor -form in the human hippocampus. Neuroscience Meeting, Los Angeles, USA, 1998, 544.13, p. 1380. De Rijk, R.H., Stam, F.J., Swaab, D.F., Vreugdenhil, E., Datson, N. Roovers, E., De Kloet, E.R., Lucassen, P.J. - Identification of the glucocorticoid receptor -form in the human hippocampus. Endocrinology Meeting Doorwerth. Fliers, E., Bisselink, J.M., Bakker, O., Wiersinga, W.M., Swaab, D.F. - Immunocytochemical localization of thyroid hormone receptor isoforms in the human hypothalamus and pituitary. 80th Annual Meeting of the Endocrine Society. Fliers, E., Guldenaar, S.E.F., Wiersinga, W.M., Swaab, D.F. - Distribution and function of thyrotropin-releasing hormone (TRH) in the human hypothalamus. Thyroid and Development 1997, 41-43. Fodor, M., Fernández-Guasti, A., Kruijver, F.P.M., Van Leeuwen, F.W., Swaab, D.F. - Stability of androgen receptor immunoreactivity during postmortem periods in rat and human hypothalamus. IV European Congress of Endocrinology. Sevilla, no. 4, p. 40, 1998. Goldstone, A.P., Bloom, S.R., Swaab, D.F. - Hypothalamic peptidergic pathways in appetite regulation. 3 rd Dutch EndoNeuro meeting 1999. Hoogendijk, W.J.G., Feenstra, M.G.P., I.E.C. Sommer, Kamphorst, W., Hofman, M.A., Pool, C.W., Eikelenboom, P., Swaab, D.F. - Do clinico-pathological correlates in depressed, or agitated AD patients provide a rationale for specific pharmacotherapeutic strategies? Neurobiol. Aging 19, #948, p. S226. Huitinga, I., Van der Cammen, M., Salm, L., Erkut, Z., Van Dam, A.M., Tilders, F., Swaab, D.F. - Interleukin-1 beta immunoreactive neurons in the human hypothalamus: changes in the paraventricular nucleus in multiple sclerosis. J. Neuroimmunol. 90, no. 410, p. 73 Kamel, D., Salehi, A., Sonnemans, M.A.F., Swaab, D.F., Van Leeuwen, F.W. - ComParison of early markers for Alzheimer s type neurodegeneration within the hypothalamaus. Neurobiol. Aging 19, #1140, p. S273. Kamel, D., Salehi, A., Sonnemans, M.A.F., Swaab, D.F., Van Leeuwen, F.W. - ComParison of early markers for Alzheimer s type neurodegeneration within the hypothalamaus. Society for Neuroscience, Los Angeles, USA, 282.17, p. 722. Liu, R., Zhou, J.N., Van Heerikhuize, J.J., Hofman, M.A., Swaab, D.F. - Decreased melatonin levels in postmortem cerebrospinal fluid in relation to aging, Alzheimer s disease and ApoE genotype. Neurobiol. Aging 19, #692, p. S165. Müller, M.B., Lucassen, P.J., Yassouridis, A., Hoogendijk, W.J.G., Holsboer, F., Swaab, D.F. - The human hippocampus in major depression or following administration of glucocorticoids: no evidence for major structural alterations., Society for Neuroscience, Los Angeles, USA, 1998, 386.14, p. 990. Müller, M.B., Lucassen, P.J., Yassouridis, A., Hoogendijk, W.J.G., Wouda, J., Holsboer, F., Swaab, D.F. - No evidence for structural alterations in the hippocampus of patients with major depression or following administration of glucocorticoids. ENA 1998, 19.26, p. 39. Müller, M.B., Lucassen, P.J., Yassouridis, A., Hoogendijk, W.J.G., Holsboer, F., Swaab, D.F. - No major pathology in the human hippocampus in major depression or following administration of glucocorticoids. A study on human postmortem tissue. XIth Congress of the European College of Neuropsychopharmacology, Paris, France, Oct. 31-Nov 4, 1998. Eur. Neuropsychopharmacology 8: P.1.188. Panayotacopoulou, M., Van Heerikhuize, J.J., Guldenaar, S.E.F., Swaab, D.F. - Tyrosine-hydroxylase mrna in neurons of the human paraventricular and supraoptic nucleus. ENA 1998, 147.09, p. 347. Ravid, R., Swaab, D.F., Kamphorst, W., Van der Valk, P., Polman, Ch., Scheltens, Ph., Barkhof, Lycklama à Nijeholt, Van Waesberghe, J.H.T.M., Van Walderveen, M.A.A. - Brain banking in multiple sclerosis combined with magnetic resonance imaging (MRI). Society for Neuroscience, 1998. Salehi, A., Swaab, D.F. - Relationship between neuronal activity, neuropathological hallmarks and genetic background in Alzheimer s disease. Neurobiol. Aging 19, #18, p. S5. Salehi, A., Ishunina, T., Swaab, D.F. - Neuronal activity in aging and Alzheimer s disease. Aging 2000 (Munich, Germany), 248: S21, 1998. Salehi, A., Pei, J.J., Verwer, R.J., Swaab, D.F. - Increased expression of GSK-3 in the nucleus basalis of Meynert and tuberomamillary nucleus in Alzheimer s disease. Society for Neuroscience, Los Angeles, USA, 116

671.8, p. 1714. Scherder, E.J.A., Van Someren, E.J.W., Swaab, D.F. - Transcutane Electrische Neuro Stimulatie (TENS) verbetert het rust-activiteitritme van patiënten in een middenstadium van de ziekte van Alzheimer, poster Centrum voor Ouderen. Swaab, D.F. - Reduced neuronal activity as the major cause of dementia in Alzheimer s disease: therapeutic strategies for reactivation. Neurobiol. Aging 19, #928, p. S221. Swaab, D.F. - Sex and gender differences in the human brain: behavioural consequences. ENA 1998, 140.03, p. 330. Swaab, D.F. - Reduced neuronal activity and reactivation in Alzheimer s disease. XIth Congress of the European College of Neuropsychopharmacology, Paris, France, Oct. 31-Nov 4, 1998. Eur. Neuropsychopharmacology 8: S.18.04. Swaab, D.F., Hoogendijk, W.J.G., Zhou, J.N. - The locus coeruleus and hypothalamus in depression: postmortem studies. National Conference on Senile Dementia and Depression. Beijing, P.R. China, Nov. 1998. 1 3. Van Someren, E.J.W., Scherder, E.J.A., Lijzenga, C., Mirmiran, M., Swaab, D.F. - Stimulation of the circadian timing system in healthy and demented elderly. Neurobiol. Aging 19, #970, p. S231. Verwer, R.W.H., Jansen, K.A., Sluiter, A.A., Terpstra, J., Pool, C.W., Swaab, D.F. - Reduced cytochrome oxidase activity in Alzheimer patients is not reflected in the immunoreactivity of its subunits, COX II and COX IV. Neurobiol. Aging 19, #1135, p. S271. Zhou, J.N., Hofman, M.A., Swaab, D.F. - Alterations in the human hypothalamus start in middle-age but are more severe in Alzheimer s disease. Neurobiol. Aging 19, #1285, p. S309. 1999 Fliers, E., Manniesing, S., Unmehopa, U.A., Wiersinga, W.M., Swaab, D.F. - Decreased neuropeptide Y immunoreactivity in the arcuate nucleus of patients with nonthyroidal illness. 81 st Ann. Meeting of The Endocrine Society Goldstone, A.P., Unmehopa, U.A, Bloom, S.R., Swaab, D.F.. - Reduced hypothalamic NPY and AGRP in Prader-Willi syndrome and human obesity. 5 th International NPY Meeting, 17-22 April, Grand Cayman. Goldstone, A.P., Bloom, S.R., Swaab, D.F. - Hypothalamic peptidergic pathways in appetite regulation. 3 rd Dutch Endo-Neuro Meeting, Doorwerth, June 2-4, p.4. Kruyver, F.P.M., Fernandez-Guasti, A., Fodor, M., Swaab, D.F. - Sex hormone receptor distribution in the human hypothalamus in relation to gender, sexual orientation and endocrine status. 3 rd Dutch Endo-Neuro Meeting, Doorwerth, June 2-4, n-7, p. 71. Riemersma, R.F., Van Someren, E.J.W., Swaab, D.F. - Prevention of nightly restlessness, depression and agitation in demented patients by stimulation of the circadian system with light and melatonin. Annual Meeting Graduate Schools, Conference Center Woudschoten. Swaab, D.F. - Sexual differentiation of the human hypothalamus. ESHRE 15 th Ann. Meeting, 27-30 June, Tours, France, p. 46 Swaab, D.F. - Neuropeptides in brain aging and Alzheimer s disease. J. Endocrinol. 160, suppl., no. S16. Swaab, D.F. - Sexual differentiation of the human hypothalamus. 22 nd Annual Meeting of the Japan Neuroscience Society, Osaka, Japan, 6-8 July 1999. Swaab, D.F. - Successful aging and the struggle against dementias. 99 International Symposium on Medicine and Pharmacology. Prevention and Treatment of Senile Diseases. p. 13 Van Leeuwen, F.W., Maat, M., Tonk, M.T., Fischer, D.F., Swaab, D.F., Hol, E.M., Roos, R.A.C. - Molecular misreading of the ubiquitin gene: a new mechanism in Huntington s disease. Neuroscience Meeting, p. 541, Van Someren, E.J.W., Scherder, E., Lijzenga, C., Swaab, D.F. - Treatment of rhythm alterations in the elderly. Int. Congress on Chronobiology, Washington 1999. Van Someren, E.J.W., Colenda, C.C., Cohen, W., McCall, W.V., Rosenquist, P.B., Swaab, D.F. - Nonparametric analysis of actigraphy data improves sensitivity to chronobiological treatment effects. Int. Congress on Chronobiology, Washington 1999. Vuijst, C.L., Unmehopa, U., Bisselink, J.M., Sluiter, A.A., Swaab, D.F., Fliers, E. - Thyroid hormone receptor isoforms in the human hypothalamus and pituitary: an immunocytochemical study. 26 th Annual meeting of the European Thyroid Association., p. C16. Riemersma, R., Van Someren, E.J.W., Swaab, D.F. - Prevention of nightly restlessness, depression and agitation in demented patients by stimulation of the circadian system with light and melatonin. Annual Meeting Graduate Schools Neurosciences Amsterdam and Pathophysiology of the Nervous System. p. E24. 2000 Chung, W.C., De Vries, G.J., Swaab, D.F. - Sexual differentiation of the human brain may extend into 117

adulthood. Abstracts 30th Annual Meeting Soc. of Neuroscience, New Orleans, USA, vol. 26, 224.2, p. 591. Fernández-Guasti, A., Fodor, M., Kruijver, F., Swaab, D.F. - Diferencias de acuerdo al sexo, pero no a la orientacion sexual, en la distribucion de receptores a androgenos en el hipotalamo humano. Memoria del XLII congresco nacional. Sociedad Mexicana de Ciencias Fisiológicas, A.C., p. S34. Hoogendijk, W.J.G., Meynen, G., Feenstra, M.G.P., Eikelenboom, P., Swaab, D.F. - Clinical implications of increased activity of surviving locus coeruleus neurons in Alzheimer's disease. The 2nd National Meeting on Dementia and Depression & International Symposium on Alzheimer's disease. May 31-June 4, Tun-Xi, China, K4. Huitinga, I., Erkut, Z.A., Van Beurden, D., Fisser, B., Swaab, D.F. - High incidence of hypothalamic lesions is related to impaired functioning of the hypothalamus-pituitary-adrenal axis. Multiple Sclerosis 6: S20. Ishunina, T.A., Swaab, D.F. - Sex- and age-related differences in the activity of arginine-vasopressin neurons in the human supraoptic nucleus are mediated via changes in estrogen receptor and immunoreactivity. Trabajos del Instituto Cajal, vol. 77, p. 125-126 Ishunina, T.A. and Swaab, D.F. - Estrogen receptor and immunoreactivity in the human supraoptic nucleus in relation to sex and age differences in the activity of arginine-vasopressin neurons. Conference on nuclear receptors in the brain. Potential targets for therapeutic agents. Oegstgeest, p. 38. Kaiser, S., Kruijver, F.P.M., Swaab, D.F., Sachser, N. - Prenatal social stress in female guinea pigs: effects on behavior, endocrine system and distribution of hypothalamic sex hormone receptors. International Behavioral Development Symposium, Biological Basis of Sexual Orientation, Gender Identity, and Gender-Typical Behavior, 25-27 May, Minot, p. 39. Kaiser, S., Kruijver, F.P.M., Swaab, D.F., Sachser, N. - Prenatal social stress in female guinea pigs: effects on behavior, endocrine system and distribution of hypothalamic sex hormone receptors. Trabajos del Instituto Cajal, vol. 77, p. 388. Kruijver, F.P.M., Pool, C.W., Hofman, M.A., Swaab, D.F., Zhou, J.N., Gooren, L.J.G. - Male-to-female transsexuals have femal neuron numbers in a limbic nucleus. International Behavioral Development Symposium, Biological Basis of Sexual Orientation, Gender Identity, and Gender-Typical Behavior, 25-27 May, Minot, p. 80. Kruijver, F.P.M., Fernandez-Guasti, A., Fodor, M., Kraan, E., Swaab, D.F. - Androgen receptor distribution in the human hypothalamus in relation to sex, gender identity, sexual orientation and endocrine status. Trabajos del Instituto Cajal, vol. 77, p. 123. Kruijver, F.P.M., Fernandez-Guasti, A., Fodor, M., Kraan, E.M., Swaab, D.F. - Androgen receptor distribution in the human hypothalamus in relation to sex, gender identity, sexual orientation and endocrine status. 4th Dutch Endo-Neuro Meeting, Doorwerth, p. 92. Lacerda, H.M., Fischer, D.F., Smit, A.G., Verhaagen, J., Ravid, R., Swaab, D.F. - Gene expression profile of Alzheimer s disease post-mortem brain employing high-densitiy cdna filters. Heidelberg, June 2000. Liu, R.-Y., Zhou, J.N., Swaab, D.F. - Alterations of the vasopressin and melatonin in aging and Alzheimer s disease. The 2 nd National Meeting on Dementia and Depression & Int. Symp. on Alzheimer s Disease. May 31- June 4, 2000, TunXi, China, S24. Liu, R.-Y., Zhou, J.N., Hoogendijk, W.J.G., Van Heerikhuize, J., Kamphorst, W., Unmehopa, U.A., Hofman, M.A., Swaab, D.F. - Alteration of vasopression mrna expression in the suprachiasmatic nucleus of the patients with Alzheimer s disease. 7 th Int. Conference on Alzheimer s Disease and Related Disorders, July 9-13, Washington DC, USA, Neurobiol. Aging 21, Abstr. 245, p. S54. Meynen, G., Hoogendijk, W.J.G., Unmehopa, U., Swaab, D.F. - Hersenveranderingen bij gedragsgestoorde Alzheimerpatiënten. AIO-dagen Psychiatrie, Zandvoort, 3/4 juli. Pasterkamp, R.J., Chung, W.C., Balfoort, M., De Vries, G.J., Swaab, D.F. - Distribution of estrogen receptors in the developing human hypothalamus. Neuroscience Meeting, New Orleans, USA, vol. 26, 224.1, 591 Raymann, R.J.E.M., Van Someren, E.J.W., Swaab, D.F. - Interaction of the circadian regulation of temperature and sleep. Annual Meeting of the Graduate School Neuroscience Amsterdam and the Graduate School Pathophysiology of the Nervous System. Woudschoten, 30 Nov and 1 Dec. K-57 Raymann, R.J.E.M., Van Wijk, P.M., Van Doornen, L.J.P. - Ambulatory measurement of fatigue during mental effort by means of critical flicker fusion frequency. J. Sleep Res. 9: S315. Riemersma, R., Van Hutten, R., Hoekstra, R., Berdowski, J., Hoogendijk, W., Scherder, E., Swaab, D.F., Van Someren, E. - The effect of light and melatonin on sleep in demented elderly. Annual Meeting of the Graduate School Neuroscience Amsterdam and the Graduate School Pathophysiology of the Nervous System. Woudschoten, 30 Nov and 1 Dec. K-55 Riemersma, R.F., Zhou, J.N., Unmehopa, U.A., Hoogendijk, W.J.G., Van Heerikhuize, J.J., Hofman, M.A., Swaab, D.F. - Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in depression. 15th Congress of the European Sleep Research Society. Istanbul, Turkey. Rodríguez-Manzo, G., Swaab, D.F., Lemus, A., Fernández-Guasti, A. - Male rat sexual activity induces changes 118

in androgen receptor-density in brain regions associated to sexual behavior expression. Trabajos del Instituto Cajal, vol. 77, p. 127. Salehi, A., Cooper, J.D., Alonso, M.A., Swaab, D.F., Mobley, W.C. - Neurotrophin receptors in Alzheimer brain and a mouse model of Down syndrome. 7 th Int. Conference on Alzheimer s Disease and Related Disorders, July 9-13, Washington DC, USA, Neurobiol. Aging 21, Abstr. 513, p. S114 Swaab, D.F. - Neuropathology of the hypothalamus and Alzheimer s disease (AD). XIIIèmes journées du gral France Alzheimer, Marseille, France, Symposium de Neurogériatrie. Swaab, D.F. - Herstel van functie door stimulatie van hersencellen: ontwikkeling in de neurologie en psychiatrie. Studiedag Vrije Universiteit Amsterdam on Multi-modale interventies bij kinderen met Attention-Deficit Hyperactivity Disorder (ADHD) en patiënten met de ziekte van Alzheimer (AD). 6 April 2000. Swaab, D.F. - Reduced neuronal activity and reactivation in Alzheimer s disease. The 2 nd National Meeting on Dementia and Depression & Int. Symp. on Alzheimer s Disease. May 31-June 4, 2000, TunXi, China, Key lecture 1. Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A. - The human hypothalamus in relation to age, sex and sexual orientation. Trabajos del Instituto Cajal, vol. 77, p. 5. Swaab, D.F.,Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A. - Sex differences in the human brain. King s College Meeting of the Physiological Society, London, UK, p. 12P. Van Hutten, D.F., Riemersma, R.F., Scherder, E.J.A., Hoogendijk, W.J.G., Hoekstra, R.A., Berdowski, J, Swaab, D.F., Van Someren, E.J.W. - Frontal task performance in demented elderly is related to the circadian amplitude in the rest-activity rhythm. European Congres on Sleep, Istanbul, Turkey. J. Sleep Res. 9: S197. Van Hutten, D.F., Riemersma, R.F., Scherder, E.J.A., Hoogendijk, W.J.G., Hoekstra, R.A., Berdowski, J, Swaab, D.F., Van Someren, E.J.W. - Sleep-wake cycle disturbance affects prefrontal functioning in demented elderly. Annual Meeting of the Graduate School Neuroscience Amsterdam and the Graduate School Pathophysiology of the Nervous System. Woudschoten, 30 Nov and 1 Dec. K-54 Van Leeuwen, F.W., Sonnemans, M.A.F., Gabreëls, B.A.Th.F., Fischer, D.F., Hol, E.M., Swaab, D.F. - Processing and secretion disorders in endocrine diseases and in Alzheimer's disease. Auckland, New Zealand, p. 27. Verhaagen, J., Blits, B., Hermens, W., Boer, G.J., Verwer, R.W.J., Swaab, D.F. - Repair of the injured nervous system by genetic therapy and transplantation. Ned. Vereniging voor Gentherapie. Zhou, J.N., Riemersma, R.F., Unmehopa, U., Hoogendijk, W.J.G., Van Heerikhuize, J.J., Hofman, M.A., Swaab, D.F. - Alterations in arginine vasopressin neurons in the suprachiasmatic nucleus in mood disorders. The 2 nd National Meeting on Dementia and Depression & Int. Symp. on Alzheimer s Disease. May 31-June 4, 2000, TunXi, China, S23. Zhou, J.N., Hu, X.-Y., Liu, R.-Y., Qing, S., Swaab, D.F. - Oestrogen receptors containing neurons decrease in the hippocampus of Alzheimer patients. 7 th Int. Conference on Alzheimer s Disease and Related Disorders, July 9-13, Washington DC, USA, Neurobiol. Aging 21, Abstr. 1211, p. S264. 2001 Alkemade, A., Unmehopa, U.A., Brouwer, J.P., Hoogendijk, W.J.G., Swaab, D.F., Fliers, E. - Decreased thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus (PVN) of patients with major depression. Fifth Dutch Endo-Neuro Meeting, Doorwerth 5-7 June 2001, p. 107. Alkemade, A., Unmehopa, U.A., Brouwer, J., Hoogendijk, W.J.G., Swaab, D.F., Fliers, E. - Decreased thyrotropin-releasing hormone gene expression in the hypothalamic paraventricular nucleus (PVN) of patients with major depression. Endocrine Society, published on the Internet 11 January 2001. Chotard, C., Ridray, S., Swaab, D.F., Schwartz, J.C., Trottier, S. - Relative préservation des neurones histaminergiques chez des patients atteints de la maladie d Alzheimer. Rev. Neurologique 157, Suppl. 10, p. AS47. 2001 Dubelaar, L., Fisser, B., Van Heerikhuize, J.J., Verwer, R., Swaab, D.F. - A decrease of neuronal metabolic activity in the nucleus basalis of Meynert of APOE E4 positive controls. Annual Meeting Graduate Schools Neurosciences Amsterdam and Pathophysiology of the nervous system 2001, Conference Center Woudschoten, p. A-2. Goldstone, A.P., Unmehopa, U.A., Bloom, S.R., Swaab, D.F. - Hypothalamic neuropeptides in Prader-Willi syndrome. Int. PWS Conference, Minnesota, June 2001. Goldstone, A.P., Unmehopa, U.A., Bloom, S.R., Swaab, D.F. - Changes in hypothalamic neuropeptide Y (NPY) and agouti-related protein (AGRP) in human illness and obesity. Association of Physicians meeting. London. (in press). Hoogendijk, W.J.G., Meynen, G., Feenstra, M.G., Eikelenboom, P., Kamphorst, W., Swaab, D.F. - Tijdschrift Gerontol. Geriatr. 32: 17-23. Kaiser, S., Kruijver, F.P.M., Sachser, N., Swaab, D.F. - Prenatal social stress in guinea pigs: sex-specific and 119

sex-reversed effects on hormones, brain and behavior. International Meeting Steroids and nervous system, Turin, Italy, February 11-14, p. 78. Kaiser, S., Kruijver, F.P.M., Sachser, N., Swaab, D.F. - Prenatal social stress induces sex-specific and sexreversed effects on sex hormone receptor expression in the guinea pig brain. Fifth Dutch Endo-Neuro Meeting, 5-7 June 2001, p. 62. Kruijver, F.P.M., Swaab, D.F. - Sex hormone receptors in the human hypothalamus in relation to gender, sexual orientation, transsexuality and endocrine status. International Meeting Steroids and nervous system, Turin, Italy, February 11-14., p. 81. Kruijver, F.P.M., Swaab, D.F. - Organizational and activating effects of sex hormones on the brain: relation to transsexuality. Fifth Dutch Endo-Neuro Meeting, Doorwerth, 5-7 June 2001, p. 62. Swaab, D.F. - Reduced neuronal activity and reactivation in Alzheimer's disease. J. Mol. Neurosci. 16: 59. Swaab, D.F. - Endocrinology of memory. 5th International Conference on Progress in Alzheimer's and Parkinson's disease. Kyoto, Japan, March 31-April 5. Swaab, D.F. - Wij zijn onze hersenen. Studium Generale, 2 oktober, Maastricht. Swaab, D.F. - Brain aging and Alzheimer s disease (AD): Use it or lose it. 22 nd International Summer School of Brain Research, Amsterdam, 20-24 August. Swaab, D.F., Chung, W.C.J., Kruijver, F.P.M., Hofman, M.A. - Sexual differentiation of the human hypothalamus. Fifth Dutch Endo-Neuro Meeting, Doorwerth, 5-7 June 2001, p. 61. Van Hutten, R., Riemersma, R., Scherder, E., Hoogendijk, W., Hoekstra, R.A., Berdowski, J., Swaab, D.F., Van Someren, E. - Sleep-wake cycle disturbance affects prefrontal functioning in demented elderly. Annual Meeting Graduate Schools Neurosciences Amsterdam and Pathophysiology of the nervous system 2001, Conference Center Woudschoten, p. A-5. Van Someren, E.J.W., Raymann, R., Drosopoulos, S., Collins, S., Vis, R., Van Krevelen, G., Swaab, D.F. - Effect of body temperature manipulation on Pulse-wave amplitude and sleep onset latency. Sleep Research Conference, USA. Verwer, R.W.J., Van Ginkel, C.J., Sluiter, A.A., Hermens, W.T., Müller, L.J., Baker, R.E., Verhaagen, J., Swaab, D.F. - Quantitative and morphological characterization of long-term cultures of post-mortem adult human brain tissue. Society for Neuroscience 2001. Verwer, R.W.J., Van Ginkel, C.J.M., Sluiter, A.A., Galjart, N., Hermens, W.T.J.M.C., Müller, L.J., Baker, R.E., Verhaagen, J., Swaab, D.F. - Culture of post-mortem adult human brain tissue: a possible approach to the study of neurodegenerative diseases? Abstract 22 nd International Summer School of Brain Research, Amsterdam, p. 101. 2002 Alkemade, A., Unmehopa, U.A., Swaab, D.F., Wiersinga, W.M., Fliers, E. - Major depression and corticosteroid treatment decrease thyrotropin-releasing hormone (TRH) gene expression in the hypothalamic paraventricular nucleus (PVN). European Thyroid Association (ETA). Chung, W.C.J., De Vries, G.J., Swaab, D.F. - Sexual differentiation of the bed nucleus of the stria terminalis in rodents and humans. Workshop on Steroid Hormones and Brain Function, Breckenridge, Colorado, USA Dubelaar, E.J.G., Verwer, R.W.H., Hofman, M.A., Van Heerikhuize, J.J., Swaab, D.F. - Lower metabolic activity in nucleus basalis of Meynert neurons in APOE 4 positive Alzheimer and control patients. Neurobiology of Aging, 23, p. S267. Dubelaar, E.J.G., Verwer, R.W.H., Hofman, M.A., Van Heerikhuize, J.J., Swaab, D.F. - Lower metabolic activity in nucleus basalis of Meynert neurons in APOE 4 positive Alzheimer and control patients. Annual Meeting Graduate School Neurosciences Amsterdam and Pathophysiology of the Nervous System. Woudschoten, Abstract Nr. D3. Dubelaar, E.J.G., Verwer, R.W.H., Hofman, M.A., Van Heerikhuize, J.J., Ravid, R., Swaab, D.F. - Lower metabolic activity in nucleus basalis of Meynert neurons in APOE 4 positive Alzheimer and control pat ients. Sixth Dutch Endo-Neuro Meeting, Doorwerth, p. 77. Goldstone, A.P., Unmehopa, U.A., Swaab, D.F. - Hypothalamic growth hormone-releasing hormone (GHRH) cell number in human illness, obesity and Prader-Willi syndrome. 8 th Annual Meeting of the Am. Endocrine Society, June 2002. OR38-5 Hestiantoro, A., Swaab, D.F. - Changing of estrogen receptor alpha expression in infundibular nucleus of elderly people, protect them against the hyperphosphorylated tau protein formation. Abstract book of 10 th World Congress on the Menopause. Berlin, Germany. Hu, X.-Y., Zhou, J.-N., Swaab, D.F. - Decreased estrogen receptor- expression in hippocampal neurons in relation to hyperphosphorylated tau in Alzheimer patients. Alzheimer Conference Stockholm, Neurobiology of Aging, 23, p. S496. Ishunina, T.A., Swaab, D.F. - Sex differences in estrogen receptor- and immunocytochemical expression in 120

the supraoptic nucleus in aging and Alzheimer s disease. 5 th International Congress of Neuroendocrinology. Liu, R., Zhou, J.-N., Kamphorst, W., Hofman, M.A., Swaab, D.F. - The first appearance of neurofibrillary tangles and plaques in the temporal cortex of aged controls is accompanied by decreased cerebrospinal fluid melatonin levels. Alzheimer Conference Stockholm, Neurobiology of Aging, 23, p. S381. Lucassen, P.J., Kuipers, A., Bauer, J., Boekhoorn, K., Ravid, R., Swaab, D.F., De Kloet, E.R., Joëls, M. - Dexamethasone induced changes in cell death and proliferation in the adult human hippocampus. FENS Forum. 3 rd Forum of European Neuroscience. 12-17 July, Paris, France. Abstr. vol. 1, Abstr. 088, poster 351. Meynen, G., Unmehopa, U.A., Van Heerikhuize, J.J., Hofman, M.A., Ravid, R., Swaab, D.F., Hoogendijk, W.J.G. - Increased arginine vasopressin mrna expression in the human supraoptic nucleus in depression. Sixth Dutch Endo-Neuro Meeting, Doorwerth, p. 53. Riemersma, R., Van Hutten, R., Kalis, A., Hoekstra, R., Hoogendijk, W., Scherder, E., Swaab, D.F., Van Someren, E. - Indirect bright light therapy decreases sleep-fragmentation in institutionalized demented elderly. Abstracts from the 8 th Int. Conference on Alzheimer s Disease and Related Disorders, Neurobiology of Aging 23, no. 1S, p. S127-S128. Riemersma, R., Van Someren, E.J.W., Swaab, D.F. - Effect van licht als interventie op nachtelijke onrust bij dementie. In Neurorevalidatie bij Dementie: realiteit of utopie? Medische Faculteit Vrije Universiteit, Amsterdam, p. 12 Riemersma, R., Van Someren, E.J.W., Swaab, D.F. - 24-hour salivary melatonin in demented elderly. Sixth Dutch Endo-Neuro Meeting, Doorwerth, p. 51. Swaab, D.F. - Neuroendocrinology of memory in Alzheimer s disease. Alzheimer Conference Stockholm, Neurobiology of Aging, 23, p. S563. Van Someren, E.J.W., Raymann, R., Drosopoulos, S., Collins, S., Vis, R., Van Krevelen, G., Swaab, D.F. - Effect of body temperature manipulation on pulse wave amplitude and sleep onset. Sleep, 25, abstract supplement 2002, 16 th Annual meeting, June 8-13, Seattle. p. A 128. Van Someren, E.J.W., Riemersma, R.F., Raymann, R.E.J.M., Swaab, D.F. - Sleep-wake rhythm disturbances in aging and dementia: mechanisms, consequences and treatment. J. Clin. Psychiatry 63: 1083-1084. Van Someren, E.J.W., Riemersma, R.F., Raymann, R.E.J.M., Swaab, D.F. - The effect of illumination and temperature on sleep-wake rhythm disturbances in the elderly. Abstracts Tenth International Conference on Environmental Ergonomics. Y. Tochihara (Ed.). Kyushu Institute of Design, Fukuoka. pp. 349-352. Van Someren, E.J.W., Riemersma, R., Raymann, R.E.J.M., Swaab, D.F. - Het effect van licht en temperatuur op verstoord slaap-waak-ritme bij ouderen. Psychopraxis jaargang 5, nr. 2, pp. 48-50. Verwer, R.W.H., Dubelaar, E.J.G., Van Ginkel, C.J.M., Sluiter, A.A., Hermens, W.T.J.M.C., Müller, L.J., Baker, R.E., Verhaagen, J., Ravid, R., Swaab, D.F. - Tissue cultures obtained from postmortem brains of control and Alzheimer patients. Alzheimer conference Stockholm. Neurobiology of Aging, 23, p. S21. Verwer, R., Hermens, W., Ter Brake, O., Sluiter, A., Müller, L., Baker, R., Verhaagen, J., Ravid, R., Swaab, D.F. - Viral vector mediated transgene expression in cultured slices of postmortem human brain tissue. Annual General Meeting of The Vereniging voor Gentherapie, 28-2-2002, Amsterdam. Verwer, R.W.H., Hermens, W.T.J.M.C., Boiten, E.F.M., Sluiter, A.A., Baker, R.E., Verhaagen, J., Ravid, R., Swaab, D.F. - Viral vector mediated transgene expression in adult human postmortem brain tissue cultures. 13 th Nectar Meeting, 12-14 December, Amsterdam p.38 Verwer, R., Sluiter, A., Hermens, W., Müller, L., Baker, R., Verhaagen, J., Ravid, R., Swaab, D. - Cultured postmortem human brain tissue slices: quantitative aspects. FENS Forum. 3 rd Forum of European Neuroscience. 12-17 July, Paris, France. Wu, Y., Feenstra, M.P.G., Zhou, J.N., Liu, R.Y., Toranõ, J.S., Van Kan, H.J.M., Fischer, D.F., Ravid, R., Swaab, D.F. - Changes of pineal melatonin synthesis and noradrenergic regulation in the earliest stages of Alzheimer disease. Annual Meeting Graduate School Neurosciences Amsterdam and Pathophysiology of the Nervous System, Woudschoten, Abstract Nr. H9. Zhou, J.-N., Liu, R.-Y., Van Heerikhuize, J.J., Hofman, M.A., Swaab, D.F. - Alterations in the circadian rhythm of salivary melatonin start already at middle-age. Alzheimer Conference Stockholm, Neurobiology of Aging, 23, p. S514. 2003 Alkemade, A., Unmehopa, U.A., Fabriek, B.O., Brouwer, J.P., Leonard, J.L., Kuiper, G.G., Visser, T.J., Swaab, D.F., Fliers, E. - Distribution of type II and III deiodinase expression in the human hypothalamus and anterior pituitary. European Congress of Endocrinology, Lyon, France, April 2003. Alkemade, A., Unmehopa, U.A., Fabriek, B.O., Brouwer, J.P., Leonard, J.L., Kuiper, G.G., Visser, T.J., Swaab, D.F., Fliers, E. - Type II and III deiodinase immunoreactivity and enzyme activity in the human hypothalamus and anterior pituitary. Endocrine Society, Philadelphia. 2003 Alkemade, A., Unmehopa, U.A., Swaab, D.F., Fliers, E. - The human hypothalamus in nonthyroidal illness. 121

ONWA, Doorwerth Alkemade, A., Unmehopa, U.A., Swaab, D.F, Wiersinga, W.M., Fliers, E. - Major depression and corticosteroid treatment decrease thyrotropin-releasing hormone (TRH) gene expression in the human hypothalamic paraventricular nucleus (PVN). European Thyroid Association, Edinburgh, October 2003. Fliers, E., Alkemade, A., Unmehopa, U.A., Fabriek, B.O., Brouwer, J.P., Leonard, J.L., Kuiper, G.G., Visser, T.J., Swaab, D.F. Type II and type III deiodinase immunoreactivity and enzyme activity in the human hypothalamus and anterior pituitary. The Endocrine Society s 85 th Annual Meeting. Goldstone, A.P., Unmehopa, U.A., Swaab, D.F. - Hypothalamic neuropeptides in Prader-Willi syndrome. 6 th European Congress of Endocrinology, Lyon, France, 2003, pp.? Ishunina, T.A., and Swaab, D.F. - Estrogen receptor immunocytochemical expression in the hypothalamus and cholinergic basal forebrain nuclei in Alzheimer s disease. 2 nd International Meeting Steroids and Nervous System. Italy. Malidelis, Y.I., Kontastavlaki, D.P., Unmehopa, U.A., Van Heerikhuize, J.J., Panayotacopoulou, M.T., Swaab, D.F. - Vasopressin neurons of the supraoptic nucleus are not activated in schizophrenia: an immunocytochemical and in situ hybridization study. 1 st International Congress on Brain and Behaviour, Thessaloniki, Nov. 20-23, 2003 Riemersma, R.F., Swaab, D.F., Van Someren, E.J.W. - Licht en melatonine: effect op slaap, stemming, en cognitie bij demente ouderen. Presentatie bij symposium Rob Sival Verwer, R.W.H., Hermens, W.T.J.M.C., Boiten, E.F.M., Sluiter, A.A., Baker, R.E., Niclou, S.P., Verhaagen, J., Ravid, R., Swaab, D.F. - Basic studies on human postmortem tissue slices exploring gene therapeutic approaches. EPN Meeting, Doorwerth. Verwer, R.W.H. and Swaab, D.F. - In vitro activation and reactivation of neurons in relation to aging and neurodegenerative diseases, in particular Alzheimer s disease. Symposium Tissue Engineering. Congress Centre De Reehorst, November 7 th, 2003. Wu, Y.H., Fischer, D.F., Zhou, J.N., Swaab, D.F. - Circadian clock genes oscillate in the human pineal gland and are desynchronized in Alzheimer disease. Annual Meeting Graduate School Neurosciences Amsterdam, Woudschoten 27-28 October 2003, p. L-1 Wu, Y.H., Feenstra, M.G.P., Zhou, J.N., Liu, R.Y., Toraño, J.S., Vankar, H.J.M., Fischer, D.F., Ravid, R., Swaab, D.F. - Changes of pineal melatonin synthesis and noradrenergic regulation in the earliest stages of Alzheimer disease. 7 th Endo-Neuro Meeting, Doorwerth, 2003. 2004 Alkemade, A., Unmehopa, U.A., Kuiper, G.G., Visser, T.J., Friesema, E.C., Swaab, D.F., Fliers, E. - Thryoid hormone transporter (MCT8) and type III deiodinase (D3) expression in the human hypothalamus and anterior pituitary. Endocrine Society. Bao, A.M., Hestiantoro, A., Van Someren, E.J.W., Swaab, D.F., Zhou, J.N. - Colocalization of corticotrophinreleasing hormone and estrogen receptor in the human paraventricular nucleus in depression. 3 rd Dutch Endo- Neuro-Psycho Meeting, Parkhotel Doorwerth, 1-4 June. p. 173 Dubelaar, E.J.G., Ter Meulen, W.G., Mufson, E.J., Van Heerikhuize, J.J., Verwer, R.W.H., Swaab, D.F. - Increased activity of nucleus basalis of Meynert neurons in mild cognitive impairment. 3 rd Dutch Endo-Neuro- Psycho Meeting, Parkhotel Doorwerth, 1-4 June. p. 191 Fronczek, R., Unmehopa, U.A., Balesar, R., Lammers, G.J., Swaab, D.F. - Immunocytochemical staining of hypothalamic hypocretin neurons in Prader-Willi patients. 3 rd Dutch Endo-Neuro-Psycho Meeting, Parkhotel Doorwerth, 1-4 June. p. 182. Huitinga, I., Van Beurden, D., Erkut, Z., Ravid, R., Swaab, D.F. - The stress-axis in MS patients. NHB in VU. 17 Feb. 2004. Huitinga, I., Van Beurden, D., Ravid, R., Swaab, D.F. - Neuroendocrine low responders in MS. Annual Meeting Dutch MS Research Foundation, 22-23 December 2004 Kontostavlaki, D., Sluijs, J.A., Unmehopa, U.A., Huitinga, I., Hol, E.M., Panayotacopoulou, M.T., Swaab, D.F. - Real- time Q-PCR on tyrosine hydroxylase immunocytochemically identified neurons of the human supraoptic nucleus isolated from cryostat sections using laser microdissection: co-expression with GTP cyclohydrolase I. FENS Lissabon Kontostavlaki, D., Sluijs, J.A., Unmehopa, U.A., Swaab, D.F., Panayotacopoulou, M.T., Huitinga, I., Hol, E.M. - Application of laser microdissection and real-time Q-PCR on immunocytochemically identified neurons of the human brain: results from post-mortem material. First International Q-PCR Symposium and Application Workshop Transcriptomics, Clinical Diagnostics & Gene Quantification. Freising-Weihenstephan, Germany, March 3-6, 2004 Kontostavlaki, D., Sluijs, J.A., Unmehopa, U.A., Huitinga, I., Hol, E.M., Panayotacopoulou, M.T., Swaab, D.F. - Real- time Q-PCR on tyrosine hydroxylase immunocytochemically identified neurons of the human supraoptic 122

nucleus isolated from cryostat sections using laser microdissection: co-expression with GTP cyclohydrolase I. 3 rd Dutch Endo-Neuro-Psycho Meeting, Parkhotel Doorwerth, 1-4 June. p.70 Raymann, R.J.E.M., Den Haan, R., Ootes, S., Van Braak, E., Bierman, D.J., Schmitt, A.J., Swaab, D.F., Van Someren, E.J.W. - Verbal episodic memory is relatively spared in elderly insomniacs. 3 rd Dutch Endo-Neuro- Psycho Meeting, Parkhotel Doorwerth, 1-4 June. p. 250. Riemersma, R.F., Swaab, D.F., Hoogendijk, W.J.G., Van Someren, E.J.W. - Light and melatonin: effect on sleep, mood, and cognition in demented elderly. Alzheimer Conference 2004 Swaab, D.F. - Reactivation of metabolically impaired neurons in Alzheimer s disease. 9 th International Conference on Alzheimer s disease and related disorders. Swaab, D.F. - The stress-axis in MS patients. NUBIN, 17 Feb. 2004 Swaab, R.I. and Swaab, D.F. - Sex differences in negotiations: combining perspectives from neurobiological and communication domains. 30 May 2004. Swaab, D.F., Hestiantoro, A. - Steroid hormones and receptors in the human brain: involvement in development, gender disorder, aging, and dementia. 11 th World Congress of Gynecological Endocrinology, Florence, Italy, PS7. Swaab, D.F. - Reactivation of metabolically impaired neurons in Alzheimer s disease. 2 nd International Congress Neuroregeneration, Rio de Janeiro, Brazil, September 20-24, 2004. Swaab, D.F., Dubelaar, E.J.G., Verwer, R.W.H. - Reactivation of metabolically impaired neurons in Alzheimer s disease. Alzheimer s Disease Congress, Philadelphia Verwer, R.W.H., Balesar, R., Wu, L., Boiten, E.F., Sluiter, A.A., Dirven, C.M., Noske, D.P., Baker, R.E., Ravid, R., Zhou, J.N., Swaab, D.F. - Tissue slice cultures from human brain autopsies and biopsies: Alzheimer's disease and other neurological disorders. 9 th International Conference on Alzheimer's Disease and Related Disorders. P2-142. Wiersinga, W.M., Alkemade, A., Unmehopa, U.A., Kuiper, G.G., Visser, T.J., Friesema, E.C., Swaab, D.F., Fliers, E. - Thyroid hormone transporter (MCT8) and deiodinase (D2 and D3) expression in the human hypothalamus. ETA. Istanbul 2004 Wu, L., Verwer, R.W.H., Sluiter, A.A., Swaab, D.F., Zhou, J.N. - Effects of rat embryonic neurospheres on the viability of cultured postmortem brain tissue slices from AD patients. 9 th International Conference on Alzheimer's Disease and Related Disorders. O4-05-03. Wu, Y.H., Fischer, D., Zhou, J.N., Swaab, D.F. - Circadian clock genes oscillate in the human pineal gland and are desynchronized in Alzheimer s disease. 3 rd Dutch Endo-Neuro-Psycho Meeting, Parkhotel Doorwerth, 1-4 June. p. 188 Wu, Y.H., Fischer, D.F., Kalsbeek, A., Garidou-Boof, M.-L., Liu, R.Y., Zhou, J.N., Swaab, D.F. -The circadian system is affected from the earliest preclinical stages onwards in Alzheimer disease. ONWA. 2005 Balesar, R.A., Wolters, P., Baker, R.E., Sluiter, A., Wu, L., Van Pelt, J., Swaab, D.F., Verwer, R.W.H. - Electrical activity in post-mortem adult human brain tissue cultures. Fourth Dutch Endo-Neuro-Psycho Meeting, Doorwerth, June 2005, p. 248. Bao, A.M., Fischer, D.F., Wu, Y.H., Unmehopa, U.A., Zhou, J.N., Swaab, D.F. - Evidence of a direct androgenic involvement in the activity of human corticotropin-releasing hormone neurons: an immunocytochemical and bandshift analysis study, p. 213. Bossers, K., Verhaagen, J., Swaab, D.F., Ravid, R., Thaete, C., Kruse, C. - Gene expression of profiling Parkinson s disease. Fourth Dutch Endo-Neuro-Psycho Meeting, Doorwerth, June 2005, p. 221. De Wit, S., Van der Windt, R., Swaab, D.F., Huitinga, I. - Decreased estrogen receptor α expression in corticotrophin-releasing hormone neurons near active hypothalamic MS lesions. Fourth Dutch Endo-Neuro- Psycho Meeting, Doorwerth, June 2005, p. 212. Winner of Poster Prize Dubelaar, E.J.G., Sluiter, A.A., Hol, E.M., Verwer, R.W.H., Swaab, D.F. - The human cholinergic, neurotrophic and metabolic response of degenerating neurons of Alzheimer s disease patients, to neurotrophic growth factors in an in vitro study. Fourth Dutch Endo-Neuro-Psycho Meeting, Doorwerth, June 2005, p.248. Erkut, Z.A., Huitinga, I., Swaab, D.F. - The HPA axis in multiple sclerosis. Fourth Dutch Endo-Neuro-Psycho Meeting, Doorwerth, June 2005. p. 82. Fronczek, R., Lammers, G.J., Balesar, R., Unmehopa, U., Swaab, D.F. - The number of hypothalamic hypocretin (orexin) neurons is not affected in Prader-Willi syndrome. 24 th International Summer School of Brain Research, 29 August-1 September, Amsterdam. Huitinga, I., Van Hulten-Van Run, P., Ravid, R., Swaab, D. - Estrogen receptor-alpha expression in reactive astrocytes in active MS lesions: implications for neuroprotective actions of estrogens? Annual MS meeting of the Dutch MS Research Foundation. 24/25 November Ishunina, T.A., Swaab, D.F. - Aromatase alterations in relation to estrogen receptor changes in aging and 123

Alzheimer's disease. Trabajos del Instituto Cajal, Torino, Italy, Feb, 13-17, 2005, p. 80-81. Ishunina, T.A., Swaab, D.F. - Neuronal metabolic changes in the hypothalamus and basal forebrain in vascular dementia. May estrogens play a role? 8 th European Congress of Neuropathology, Amsterdam, 25-28 June. Koning, N., Swaab, D.F., Van Lier, R.A., Huitinga, I., Hoek, R.M. - The role of CD200-CD200 receptor interaction in the regulation of microglia and macrophages in multiple sclerosis. Fourth Dutch Endo-Neuro- Psycho Meeting, Doorwerth, June 2005. Winner of Poster Prize Lutgens, S.I., Sluiter, A.A., Baker, R.E., Swaab, D.F., Verwer, R.W.H. - Quantitative analysis of living cells in post-mortem human brain samples in relation to neurotrophic factors. Fourth Dutch Endo-Neuro-Psycho Meeting, Doorwerth, June 2005, p. 247. Swaab, D.F. - Sexual differentiation of the human brain and gender. 24 th Joint Meeting of the British Endocrine Societies, Harrogate, UK, Endocrine Abstracts, 4-6 April 2005, S44. Swaab, D.F., Fronczek, R., Lammers, G.J., Balesar, R., Unmehopa, U.A. - Hypothalamic alterations in Prader- Willi syndrome (PWS): focus on the orexin system. Symposium on Orexins / Hypocretins, Dusseldorf/Cologne, Germany, 20-24 July 2005. Swaab, D.F. - Sex differences in the human brain and gender. DANA, Centre for the Brain, London, UK, 5 July. Van de Nes, J.A.P., Konermann, S., Nafe, R., Swaab, D.F. - β-protein/a4 deposits are not associated with hyperphosphorylated tau in somatostatin neurons in the hypothalamus of Alzheimer s disease patients. AMC Neuropathology Conference, 2005 Van de Nes, J.A.P., Nafe, R., Konermann, S., Schlote, W. - Tau hyperphosphorylation and neuronal atrophy are not related in the medial temporal neocortex of Alzheimer's disease patients. 8 th European Congress of Neuropathology, Amsterdam, 25-28 June Verwer, R.W.H., Wu, L., Sluiter, A.A., Swaab, D.F., Zhou, J.N. - Rat embryonic neurospheres improve membrane integrity of neurons in co-cultured postmortem brain tissue slices from AD and control patients. 5 th Days of Molecular Medicine Meeting. Stem Cells 2005, 17-20 March 2005, San Diego, USA. Wu, L, Zhou, J.N., Sluiter, A.A., Baker, R.E., Swaab, D.F., Verwer, R.W.H. - Rat neural precursor cells improve viability of neurons in co-cultured postmortem human brain tissue slice. Fourth Dutch Endo-Neuro-Psycho Meeting, Doorwerth, June 2005, p. 246. Wu, Y.H., Fischer, D.F., Swaab, D.F. - A promoter polymorphism in the monoamine oxidase A gene modulates the susceptibility to monoamine oxidase A dysfunction in Alzheimer s disease. Fourth Dutch Endo-Neuro- Psycho Meeting, Doorwerth, June 2005, p. 204. 2006 Bao, A.M., Swaab, D.F. - Corticotropin-releasing hormone neurons in the paraventricular nucleus of the human hypothalamus in subjects with normal and abnormal sex hormone status. Experimental Gerontology. Bregenz meeting, Bregenz, Austria. Bao, A.M., Swaab, D.F. - Corticotropin-releasing hormone neurons in the paraventricular nucleus of the human hypothalamus in relation to sex and aging. 37 th Annual ISPNE Conference, Leiden, Hormones & Brain. From Cloning to Clinic. S022, p39. Hestiantoro, A., Swaab, D.F. - Neurons surrounded by basket-like estrogen receptor (ER)β containing terminals in the hypothalamic infundibular nucleus are not affected by neurofibrillary Alzheimer's disease pathology. Gynecol. Endocrinol. 22: 153. Swaab, D.F. - Degeneration and reactivation of metabolically impaired neurons in aging, Alzheimer's disease and depression. 37 th Annual ISPNE Conference, Leiden, Hormones & Brain. From Cloning to Clinic. S041, p. 49 Swaab, D.F. - Sex differences in the human brain, normal and irregular. 12 th Meeting of the European Neuroendocrine Association, Athens, Greece, October 21-24 2006, vol. 5, suppl. 1, p.32. Wu, L., Sluiter, A.A., Balesar, R.A., Baker, R.E., Swaab, D.F., Zhou, J.N., Verwer, R.W.H. - In vitro production of survival enhancing factors by neural stem cells. ENP meeting 2006. 2007 Bao, A.-M., Swaab, D.F. Gender difference in age-related number of corticotropin-releasingf hormone expressing neurons in the human hypothalamic paraventricular nuclears and the role of sex hormones. 4 th International Meeting, Steroids and Nervous System, Villa Gualino, Turin, Italy, February 17-21, p. 265-266. Bossers, K., Kruse, C., Verhaagen, J., Swaab, D.F. - Gene expression changes in the course of Alzheimer's disease. Neuroscience Meeting, San Diego, November 3-7 Ishunina, T.A., Swaab, D.F. - Canonical and alternatively spliced estrogen receptor α in the human mamillary bodies and hippocampus in aging and Alzheimer's disease. 4 th International Meeting, Steroids and Nervous System, Villa Gualino, Turin, Italy, February 17-21, p. 43-44. Ishunina, T.A., Swaab, D.F. Alterations in the human brain in menopause. Menopause Meeting, Amsterdam, 19-21 June. 124

Klomp, A., Bao, A.-M., Pool, C.W., Van Heerikhuize, J.J., Balesar, R., Swaab,D.F. GABAergic innervation of the hypothalamic paraventricular nucleus in mood disorder. ENP meeting 2007. Swaab, D.F. Human brain sex differences in relation to gender, sexual orientation and brain disorders. 4 th International Meeting, Steroids and Nervous System, Villa Gualino, Turin, Italy, February 17-21, p. 53. Swaab, D.F., Bao, A.-M. The stress system in the human brain in depression and neurodegeneration. 4 th International Meeting, Steroids and Nervous System, Villa Gualino, Turin, Italy, February 17-21, p. 125-126. Swaab, D.F., Bao, A-M, Ishunina, T.A. - Sexual differentiation in the human brain. The 2 nd World Congress on Gender-Specific Medicine and Ageing. The Endocrine Impact, Rome, Italy, March 8-11, p. A38. Wu, Y.H., Swaab, D.F. - The circadian timing system in Alzheimer's disease. Endo-Neuro-Psycho meeting, Doorwerth, 5-8 June. 2008 Bossers, K. Meerhoff, G., Essing, A., Van Dongen, J., Houba, P., Kruse, C., Verhaagen, J., Swaab, D. - Gene expression changes in the human prefrontal cortex during the progression of Alzheimer's disease. 25 th International Summer School of Brain Research, Neurotherapy. Progress in Restorative Neuroscience & Neurology. Amsterdam, 25-28 August, pp. 80-81. Korecka, J.A., Blaas, E., Unmehopa, U.A., Balesar, R.A., Van Kesteren, R.E., Smit, A.B., Bossers, K., Swaab, D.F., Verhaagen, J. - Selecting and validating gene targets responsible for Parkinson's disease development and progression. Endo-Neuro-Psycho meeting, Doorwerth, 4-6 June. Korecka, J.A., Blaas, E., Unmehopa, U.A., Balesar, R.A., Van Kesteren, R.E., Smit, A.B., Bossers, K., Swaab, D.F., Verhaagen, J. - Selecting and validating gene targets responsible for Parkinson's disease development and progression. 25 th International Summer School of Brain Research, Neurotherapy. Progress in Restorative Neuroscience & Neurology. Amsterdam, 25-28 August, pp. 95. Lucassen, P.J., Wouda, J., Marlatt, M., Boekhoorn, K., Kolk, S.M., Aronica, E., Swaab, D.F., Vreugdenhil, E., Verwer, R.W.H. - Doublecortin(-like) proteins in early mouse development and adult human brain. Endo-Neuro- Psycho meeting, Doorwerth, 4-6 June. Lucassen, P.J., Marlatt, M., Krugers, H., Joels, M., Van Leuven, F., Swaab, D.F., Verwer, R., Boekhoorn, K. - Neurogenesis in relation to aging and dementia. Eur. Neuropsychopharmacology 18 (suppl. 4), 2008, S178. Shan, L., Liu, C.-Q., Balesar, R., Swaab, D.F., Bao, A.-M. - Stable histamine production in spite of extensive Parkinson pathology in the hypothalamic tuberomamillary nucleus. 25 th International Summer School of Brain Research, Amsterdam, 25-28 August 2008. Vo, T.T., Carulli, D., Ehlert, E.M.E., Kwok, J.C.F., Asher, R.A., Fawcett, J.W., Verhaagen, J. - The chemorepulsive axon guidance protein Semaphorin 3A is a constituent of perineuronal nets in the adult rodent brain. 25 th International Summer School of Brain Research, Neurotherapy. Progress in Restorative Neuroscience & Neurology. Amsterdam, 25-28 August, pp. 115. 2009 Garcia-Falgueras, A., Swaab, D.F. - A sex difference in the hypothalamic uncinate nucleus: relationship to gender identity. Trabajos del Instituto Cajal, 5 th Int. Meeting Steroids and Nervous System, 13018 February 2009, Turin, Italy, p. 209. Ishunina, T.A., Swaab, D.F. - Estrogen receptor alpha splice variants in the brain of the elderly people. Trabajos del Instituto Cajal, 5 th Int. Meeting Steroids and Nervous System, 13018 February 2009, Turin, Italy, p. 227-228. Korecka, J.A., Blaas, E., Van Kesteren, R.E., Smit, A.B., Swaab, D.F., Bossers, K., Verhaagen, J. - Gene expression profiling of Retinoic acid differentiated human neuroblastoma SH-SY5Y cells. Prague, Czech Republic. Luchetti, S., Bossers, K., Van de Bilt, S., Frajese, G., Agrapart, V., Ramirez Morales R., Bernardi, G., Frajese G.V., Swaab, D.F. - Neurosteroid biosynthetic pathways in the human brain: gene expression changes in Alzheimer's and Parkinson's disease. Trabajos del Instituto Cajal, 5 th Int. Meeting Steroids and Nervous System, 13018 February 2009, Turin, Italy, p. 246-247. Riemersma-van der Lek, R., Swaab, D.F., Twisk, J., Hol, E.M., Hoogendijk, W.J.G., Van Someren, E. - Melatonin in elderly patients. Biol. Rhythms Res. 40: 83-84. Shan, L., Liu, C.-Q., Balesar, R., Swaab, D.F., Bao, A.-M. - Stable histamine production in spite of extensive Parkinson pathology in the hypothalamic tuberomamillary nucleus. Exp. Gerontol. 44: 126-134. Swaab, D.F., Garcia-Falgueras, A. - Sexual differentiation of the human brain in relation to gender identity and sexual orientation. Trabajos del Instituto Cajal, 5 th Int. Meeting Steroids and Nervous System, 13018 February 2009, Turin, Italy, p. 20. Zhou, T., Wang, S.-S., Kamphuis, W., Wang, G.-H., Zhou, J.-N., Swaab, D.F. - DCNP1 up-regulates corticotropin-releasing hormone gene expression and may play a role in depression. Exp. Gerontol. 44: 126-134. 125

Wang, Q., Wouda, J., Seress, L., Van Heerikhuize, J., Swaab, D.F., Joels, M., Lucassen, P.J. - Glucocorticoid receptor expression in the human hippocampus; changes with age. Miezlaiskyte, A., Dijkstra, F., Unmehopa, U., Swaab, D.F. - Novel insights in Prader-Willi syndrome. 8th Dutch Endo-Neuro-Psycho Meeting, Doorwerth 3-5 June 2009 Luchetti, S., Bossers, K., Van de Bilt, S., Frajese, G., Agrapart, V., Ramirez Morales, R., Bernardi, G., Swaab, D.F. - Neurosteroid biosynthetic pathways in the human brain: gene expression changes in Alzheimer's and Parkinson's disease. Trabajos del Instituto Cajal, vol. LXXXII, 2009, pp. 246-247. Ishunina, T., Swaab, D.F. - Estrogen receptor alpha splice variants in the brain of postmenopausal and Alzheimer's disease women. Abstract 244, 8 th European Congress on Menopause (EMAS), London, UK, May 16-20, 2009. Swaab, D.F. - Validation of animal-model circadian-system changes in aging for human brain disorders. XI. Congress of the European Biological Rhythms Society, Strasbourg, France, August 22-28, 2009, S16. Van Someren, E.J.W., Riemersma-Van der Lek, R.F., Swaab, D.F. - Effects of the aging biological clock and treatment in demented elderly. XI. Congress of the European Biological Rhythms Society, Strasbourg, France, August 22-28, 2009, S16-1 Wirz, K.T.S., Bossers, K., Korecka, J.A., Zwart, R., Schepers, W., Swaab, D.F., Verhaagen, J. - Functional characterization of target genes involved in Alzheimer's disease development and progression. FIGON geneesmiddelendagen, October 2009. Ishunina, T, Swaab, D.F. - Estrogen receptor alpha splice variants in the brain of postmenopausal and Alzheimer's disease women. Maturitas vol. 63, suppl. 1, p. S64. Wang, Q., Wouda, J., Seress, L., Van Heerikhuize, J., Swaab, D.F., Joels, M., Lucassen, P.J. - Glucocorticoid receptor expression in the human hippocampus. 8 th Dutch Endo-Neuro-Psycho Meeting Dordrecht, 3-5 June 2009. 2010 Alkemade, A., Unmehopa, U., Hessel, E.V.S., Swaab, D.F., Kalsbeek, A., Fliers, E. - Suppressor of cytokine signaling 3 (SOCS3) expression in the post-mortem human hypothalamus and its relationship with pre-mortem serum leptin. Endocrine Society, San Diego, USA, June 19-22, 2010 Alkemade, A., Harakalova, M., Swaab, D.F., Fliers, E., Kalsbeek, A. - Decreased α melanocyte stimulating hormone (αmsh) expression in the hypothalamic infundibular nucleus of subjects with type 2 diabetes. Endocrine Society, San Diego, USA, June 19-22, 2010. Garcia-Falgueras, M.A., Ligtenberg, L., Kruijver, F., Swaab, D.F. - Galanin neurons in the sexually dimorphic nucleus of the human preoptic area (SDN-POA) in relation to sex, age and gender identity. FENS, Rai, Amsterdam, 3-7 July 2010. Zhao, J., Bao, A.-M., Hoogendijk, W.J.G., Qi, X.R., Kamphuis, W., Luchetti, S., Meynen, G., Lou, J.-S., Swaab, D.F. - Alterations in GABA and glutamate pathways in the prefrontal cortex in major depressive disorder, bipolar depression and depression in Alzheimer's disease. FENS, Rai, Amsterdam, 3-7 July 2010. Luchetti, S., Bossers, K., Van de Bilt, S., Agrapart, V., Ramirez Morales, R., Frajese G.V., Swaab, D.F. - Neurosteroid biosynthetic pathway changes in Alzheimer's and Parkinson's disease. FENS, Rai, Amsterdam, 3-7 July 2010. Xin-Rui, Q., Zhou, J.N., Kamphuis, W., Wang, Q., Lucassen, P.J., Swaab, D.F. - Expression of stress-related genes in the prefrontal cortex in mood disorders. FENS, Rai, Amsterdam, 3-7 July 2010. Wang, Q., Joels, M., Seress, L., Aronica, E., Van Heerikhuize, J., Swaab, D.F., Lucassen, P.J. - Glucocorticoid receptor expression in the human hippocampus: changes with age and in depression. FENS, Rai, Amsterdam, 3-7 July 2010. Bossers, K., Meerhoff, G., Essing, A., Van Dongen, J.W.F., Houba, P., Kruse, C.G., Verhaagen, J., Swaab, D.F. - Concerted changes in gene expression in the prefrontal cortex precede neuropathology in Alzheimer's disease. FENS, Rai, Amsterdam, 3-7 July 2010. Korecka, J.A., Eggers, R., Swaab, D.F., Bossers, K., Verhaagen, J. - Creating an in vivo Parkinson disease model using AAV-mediated transgene expression in the Substantia Nigra pars compacta and MPTP induced neuronal degeneration. FENS, Rai, Amsterdam, 3-7 July 2010. Wirz, K.T.S., Bossers, K., Stargardt, A., Kamphuis, W., Swaab, D.F., Hol, E.M., Verhaagen, J. - Genome-wide transcriptional alterations before, during and after the development of amyloid beta neuropathology in the frontal cortex of the APPswe/PS1dE9 transgenic mouse model for Alzheimer's disease. FENS, Rai, Amsterdam, 3-7 July 2010. Luchetti, S, Bossers, K., Van de Bilt, S., Agrapart, V., Ramirez Morales, R., Frajese, G.V., Swaab, D.F. - Neurosteroid biosynthetic pathway changes in Alzheimer's and Parkinson's disease. FENS 2010, Amsterdam Garcia-Falguera, A., Ligtenberg, L., Kruijver, F.P.M., Swaab, D.F. - Galanin neurons in the sexually dimporphic nucleus of the human preoptic area (SDN-POA) in relation to sex, age and gender identity. FENS 2010, 126

Amsterdam. Taziaux, M., Starphorius. M., Swaab, D.F., Bakker, J. - Distribution of neurokinin B in the human hypothalamus: an immunohistochemical study. Society for Neuroscience 2010. Zwinderman, A.H., Sprangers, M.A., Baas, F, Van Noorden, C.J., Radbruch, L.. Davies, A., Swaab, D.F., Sloan, J., Kaasa, S., Skorpen, F., Klepstad, P. - Genes selected for their relevance to pain are also associated with fatigue and dyspnea: evidence of the European pharmacogenetic opioid study. ISOQOL (International Society for Quality of Life Research). Korecka, J.A., Eggers, R., Swaab, D.F., Bossers, K., Verhaagen, J. - Creating an in vivo Parkinson disease model using AAV-mediated transgene expression in the substantia nigra pars compacta and MPTP induced neuronal degeneration. FENS 2010, Amsterdam Swaab, D.F. - Gender identity and sexual differentiation of the human brain. European Society for Paediatric Endocrinology (ESPE), Prague, Czech Republic, September 22-25, 2010. Garcia-Falgueras, A., Ligtenberg, L., Kruijver, F.P.M., Verwer, R., Swaab, D.F. Decrease in galanin neuron number in the intermediate nucleus of the human preoptic area (InM) in aging men: possible relation with testosterone. Torino meeting 2010 Swaab, D.F. De evolutie van onze hersenen. Natuurkundige voordrachten, no. 88, seizoen 2009-2010. Drukkerij Vis Offset Alphen aan den Rijn 2010. 2011 Wirz, K.T.S., Stargardt, A., Bossers, K., Kamphuis, W., Swaab, D.F., Hol, E.M., Verhaagen, J. - ABETA pathology triggers changes of transcripts involved in immune response but not in synaptic activity in the frontal cortex of APPSWE/PSIDE9 mice. AD/PD meeting, March 2011. Borgers, A.J., Fliers, E., Siljee, J., Swaab, D.F., Bisschop, P.H., Alkemade, A. Arginine vasopressin immunoreactivity in the suprachiasmatic nucleus is decreased in patients with a suprasellar tumor and visual field defects. Society for Endocrinology, Boston, USA, June 2011. Taziaux, M., Swaab, D.F., Bakker, J. Neurokinin B in the human infundibular nucleus: sex difference and developmental aspects. In: Trabajos del Instituto Cajal, 6 th Int. Meeting Steroids and Nervous System, Villa Gualino, Torino, Italy, February 19-23, 2011, p. 57 Garcia-Falgueras, A., Ligtenberg, L., Kruijver, F.P.M., Verwer, R., Swaab, D.F. Decrease in galanin neuron number in the intermediate nucleus of the human preoptic area (INM) in aging men: possible relation with testosterone. In: Trabajos del Instituto Cajal, 6 th Int. Meeting Steroids and Nervous System, Villa Gualino, Torino, Italy, February 19-23, 2011, p. 165 Luchetti, S., Van Eden, C., Melief, J., Swaab, D.F., Huitinga, I. Neurosteroid synthetic pathway changes in multiple sclerosis chronic active and chronic inactive lesions. In: Trabajos del Instituto Cajal, 6 th Int. Meeting Steroids and Nervous System, Villa Gualino, Torino, Italy, February 19-23, 2011, p. 185 Swaab, D.F., Bao, A.-M. Re-activation of neurons in Alzheimer s disease. Swaab, D.F. - Sexual differentiation of the human brain: consequences for gender-identity, sexua orientation and neuropsychiatric disorders. SiNapsa Neuroscience Conference 11, Ljubljana, Slovenia, 25 September 2011. 2012 Swaab, D.F. The human hypothalamus in health and disease. NH Conference Centre Leeuwenhorst, Noordwijkerhout, 11/12 February 2012. Klomp, A., Lucassen, P.J., Meerhoff, G.F., de Bruin, K., Iyer, A.M., Denys, D., Swaab, D., Booij, J., Feenstra, M., Aronica, E., Reneman, L. Lasting effects of chronic fluoxetine treatment on the late developing rat brain: age-dependent changes in the serotonergic neurotransmitter system. Fens Forum 2012, Barcelona, Spain. Bossers, K., Lau Poui Cheung, P., Salta, E., Sala Frigerio, C., Swaab, D.F., Verhaagen, J., De Strooper, B. Elucidating the microrna profile of Alzheimer s disease. Society for Neuroscience, New Orleans, USA, October 2012. Shan, L., Bao, A.M., Swaab, D.F. The human histaminergic system in health and neuropsychiatric disorders: a postmortem study. Society for Neuroscience, New Orleans, USA, October 2012 Korecka, J., Eggers, R., Van Kesteren, R.E., Blaas, E., Raas-Verloop, N., Pasterkamp, R.J., Smit, A.B., Swaab, D.F., Bossers, K., Verhaagen, J. Repulsive guidance molecule a induces degeneration of dopaminergic neurons in the adult mouse substantia nigra: implications for Parkinson s disease. Society for Neuroscience, New Orleans, USA, October 2012 Klomp, A, Lucassen P.J., Meerhoff, G.F., Hamelink, R., De Bruin, K., Iyer, A.M., Denys, D., Swaab, D.F., Feenstra, M.G., Booij, J., Aronica, E., Reneman, L. Lasting effects of chronic fluoxetine treatment on the developing rat brain: changes in the serotonergic neurotransmitter system. 8 th FENS, Barcelona, 14-18 July 2012. 127

PAPERS READ if not mentioned in 'lectures' and 'abstracts' (incl. posters) All exclusively by Swaab, D.F., unless otherwise stated. 1967 - Histochemische lokalisatie van hypofysiotrope functies in de hypothalamus. Sectie voor Vergelijkende Endocrinologie van de Nederlandse Vereniging voor Endocrinologie, Amsterdam. 1969 - Neurosecretory activity. Workshop Conference, "Integration of Endocrine and Non-endocrine Mechanisms in the Hypothalamus". Stresa, Italy. - The relation between the neurosecretory activity and the level of gonadotropic hormones. 5th Conference of Eur. Comparative Endocrinologists, Utrecht. 1970 - Neurosecretie en voortplanting bij de rat. Ned. Ver. v. Endocrinologie, Groningen. - Some factors influencing the neurosecretory activity. Univ. of Bristol, Dept. of Pharmacology, Bristol, UK. - Een semi-quantitatieve histochemische methode voor de bepaling van TTP-ase. Werkgroep Coupehistochemie van de Ned. Ver. v. Histochemie en Cytochemie, Utrecht. 1971 - Toepassing van de kwantitatieve histochemie in het hypothalamus onderzoek. Werkgroep voor Kwantitatieve Histochemie v.d. Ned. Ver. v. Histochemie en Cytochemie, Leiden, January 8. - Problemen van substraatmetingen in de hypothalamus. FUNGO Workgroup, "Regulatie van de Hypofyse Functies", Amsterdam, January 26. - Pitfalls in the determination of substrates in rat and mouse brain. Ned. Ver. v. Histochemie en Cytochemie, Rotterdam, April 2. 1972 - Enkele parameters van het onderzoek van de stimulatie van het hypothalamus- neurohypofyse systeem. Sectie Vergelijkende Endocrinol., Ned. Ver. v. Endocrinologie, April 2. 1973 - De organiserende en stimulerende invloed van steroïden op sexueel gedrag van de rat. Medische sectie van de Dr. J. Rutgers Stichting, Utrecht, January 6. - Neuro-endocriene regulatie van intra-uterine groei en baring. Commissie van Toezicht en Advies. KNAW, Amsterdam, January 19. - Neuroendocriene regulatie van intra-uteriene groei en baring. Amsterdamsche Neurologenvereeniging, Amsterdam, May 3. - Neuroendocrinologie op het Nederlands Centraal Instituut voor Hersenonderzoek. FUNGO-werkbezoek NCIH, Amsterdam, November 15. - Immunofluorescentie van vasopressine. FUNGO-werkbezoek NCIH, Amsterdam, November 15. 1983 - Clinical aspects of the developmental toxicology. Symp., "Developmental Toxicology. Chemical Risks for Reproduction and Posterity", Annual Meet. of the Dutch Soc. for Toxicology, Wageningen, January 5. - Neuropeptides, memory and aging. Symp., "The Aging Brain, Dementia and Memory Impairments", Nijmegen, March 17-18. - Possible mechanisms underlying the teratogenic effects of medicins on the developing brain. EFCNS Congr., "Prenatal Development Disturbances", Noordwijkerhout, June 13-17. - The vasopressin cell in the human suprachiasmatic, paraventricular and supraoptic nucleus in relation to aging. Autumn Meet. FUNGO workgroup "Development and Aging of the Nervous System and Behavior", Amsterdam, October 25. - Changes with aging and dementia in the vasopressin neurons of the man supraoptic nucleus and suprachiasmatic nucleus. Eurage Workshop, "Aging of the Brain and Senile Dementia; the Inventory of EEC Potentialities", San Miniato, Pisa, Italy, November 18-19. 128

1984 - The vasopressin cell in the suprachiasmatic, supraoptic and paraventricular nucleus in the human brain; changes in relation to age, sex and dementia. Symposium: "Comparative Aspects of Opioid and Related Mechanisms", State Univ. of New York, College at Old Westberry, USA, May 31. - Peptides in the brain; neurohormones and neurotransmitters. Cornell University, Ithaca, New York, USA, June 1. The Netherlands Institute for Brain Research. Cornell University, Ithaca, New York, USA, June 4. - Fetal oxytocin and vasopressin in relation to fetal development and labor. Special Reproductive Endocrinology Seminar, Cornell Univesity, Ithaca, New York, June 4. - Behavioral teratology; mechanisms and consequences. Physiology seminar, Cornell University, Ithaca, New York, USA, June 5. - Magnocellular and parvocellular vasopressin nuclei in demented and non-demented old people. Neuroscience seminar, Massachusetts General Hospital, Harvard Med. School, Dept. of Neurology, Boston, USA, June 7. - Permanent functional CNS deficits due to chemical given during intrauterine development. Seminar, Shriver Center for Mental Retardation, Boston, USA, June 8. - The suprachiasmatic nucleus of the human brain in relation to sex, age and senile dementia. ENA- Satellite Workshop, Boerhaave Course: "Modern Techniques in the Study of Morphology of the Nervous System", Leiden, September 17-18. - Permanente effecten van chemische stoffen op de hersenontwikkeling. Voordracht Symposium " Genees- en Genotmiddelen in de Zwangerschap", Reinier de Graaf Gasthuis, Delft, October 9. - Het onderzoeksprogramma van het Ned. Inst. voor Hersenonderzoek. Lezing Afd. Neurologie, Acad. Med. Centrum, Amsterdam, October 29. - Peptiden in de menselijke hersenen. Lezing Symposium Biologische Raad, "Neuropeptiden, Hersenen en Gedrag", Kon. Ned. Acad. van Wetensch., Amsterdam, November 2. - Pre- and perinatal neuroendocrine control of pituitary hormones. Symposium, "Fetal Neuroendocrinology", Mariensee, Germany, November 8. - Peptiden, van neurohormonen tot transmitters. Najaarsvergadering Nederlandse Vereniging voor Endocrinologie, Preklinisch Instituut der Kath. Univ. Nijmegen, November 16. - Geslachtelijke differentiatie van de hersenen bij de mens. Vergadering der Amsterdamsche Neurologenvereeniging, Ned. Inst. v. Hersenonderzoek, Amsterdam, December 6. - Neuropeptides in aging and dementia. Scientific Meeting, "Senile Dementia and Stroke: Therapeutic Possibilities", Amsterdam, December 6. 1985 - Dementia research in the Netherlands. European Steering Committee of the WFN Research Group on the Dementias, Munich, FRG, January 12-13. - FUNGO Werkgemeenschap Ontwikkeling en Veroudering van Zenuwstelsel en Gedrag. Kunnen degeneratieve veranderingen in (vasopressine)neuronen tijdens veroudering en dementie voorkomen worden door hen te activeren? IOI, AMC, Amsterdam, January 29. - Neurochemical strategies, Eurage Workshop, "Clinical, Pathological and Neurochemical Opportunities for Collaborative Research in Dementia", Newcastle-upon-Tyne, UK, June 5-7. - Neuropeptides and growth factors in Alzheimer's disease. XIIIth World Congress of Neurology, Hamburg, FRG, September 1-6. - Drug effects on brain development. Symp., "Developmental Clinical Pharmacology", Academic Medical Center, Amsterdam, September 16. - The long-term effects of drugs utilized in pregnancy. 16th Ann. Meet. of the Perinatal Research Society, Cape God, USA, September 30. - A sexually dimorphic nucleus. Seminar of Dept. of Neurobiol. and Anatomy, Univ. of Rochester, USA, October 2. - Changes of vasopressin neurons in aging and Alzheimer's disease. Seminar of Dept. of Neurobiol. and Anatomy, Univ. of Rochester, USA, October 3. - Functionele teratologie blijvende effecten van geneesmiddelen toegediend tijdens de zwangerschap. Ned. Werkgroep voor Perinatale Biologie, Utrecht, November 1. - Het vasopressineneuron in veroudering en dementie. FUNGO-wgm. "Ontwikkeling en Veroudering van Gedrag". Retraite Stevensbeek, November 5-6. - Kunnen degeneratieve veranderingen in (vasopressine)neuronen tijdens veroudering en dementie 129

voorkomen worden door hen te activeren? FUNGO-retraite, dwarsverband i.o. "Etiologie van Veroudering", November 14-15. 1986 - Fundamenteel onderzoek van hersenen en het gebruik ervan door medici. Jaarvergadering Nederlandse Dierkundige Vereniging, Fundamenteel Zoölogisch Onderzoek en Maatschappij, KNAW, Amsterdam, February 21. - What could be considered as a normal control for a brain bank? Brain Tissue Bank Meeting, Centre National de la Recherche Scientifique et Association Claude Bernard, Lab. de Neuropathologie Charles Foix, Hopital de la Salpêtrière, Paris, France, March 11. - Effecten van anaesthetica, op de hersenontwikkeling van het kind. Colloquium afd. Anaesthesie, AMC, Amsterdam, May 7. - Are the human and rat suprachiasmatic nucleus homologous? 10th Ann. Meet. of the Eur. Neuroscience Association, Marseille, France, September 15. - Strategie van hersenonderzoek betreffende de veroudering en de ziekte van Alzheimer. Workshop `Veroudering en Wetenschap', Amsterdam, October 24. - De sexueel dimorfe kern in ontwikkeling en veroudering. MEDIGON-werkgemeenschap `Ontwikkeling en veroudering van het zenuwstelsel en gedrag', Amsterdam, October 29. 1987 - De noodzaak van menselijk hersenweefsel voor het onderzoek naar veroudering en dementie. SOOM Symp. `Wijzer over Ouder', Utrecht, January 1. - Mogelijkheden en onmogelijkheden bij de therapie van de ziekte van Alzheimer. Organon, Arnhem, April 7. - Psychofarmaca en de hersenontwikkeling van het kind. Symposium Psychofarmaca tijdens graviditeit en lactatieperiode. Sophia Ziekenhuis, Zwolle, April 9. - De hypothalamus van de mens in relatie tot geslacht, veroudering en de ziekte van Alzheimer. Nederlandse Vereniging voor Neuropathologie, Utrecht, April 24. - Research on ageing of the brain and dementia in the Netherlands. Eurage, Neth. Inst. for Brain Res., Amsterdam, May 6. - Mogelijkheden en moeilijkheden bij het neurobiologisch onderzoek van menselijk weefsel. Neuroanatomische Methodendag, Rotterdam, June 5. - Sexual differentiation of the brain. 10th Int. Symp. Gender Dysphoria, Amsterdam, June 12. - Introduction to the C.U. Ariëns-Kappers lecture. 15th Summer School of Brain Research, "Neurochemistry of Functional Neuroteratology", Amsterdam, September 4. - Sexualiteit en wetenschap: Neurobiologische aspecten. Studiedag Universiteit van Amsterdam, October 2. - The view of a neurobiologist on ageing. Cell biological Basis of Aging, Cell Biology & Medigon Study Group on Gerontology. Veldhoven, October 15. - Differential cell loss in the hypothalamus anterior with aging and Alzheimer's disease. Poster, Velthoven, Oct. 15. - Betekenis van functionele neuroteratologie voor de ontwikkelingsteratologie. MEDIGON retraite, Noordwijkerhout, October 30/31. - Kunnen degeneratieve veranderingen in (vasopressine) neuronen tijdens veroudering en dementie voorkomen worden door hen te activeren? MEDIGON-retraite, Noordwijkerhout, October 30/31. - Veranderingen in de SCN tijdens veroudering en dementie. Werkgroep `Veroudering en dementie', NIH, Amsterdam, November 3. - Chemie en voorplanting. Minisymposium "Chemie en voortplanting", Vrije Universiteit, Amsterdam, Nov. 20. - Sexual differentiation of the human brain. The Rockefeller Univ., NY, NY, USA, December 7. - The suprachiasmatic nucleus in ageing and Alzheimer's disease. Institute for Basis Research in Developmental Disabilities, Staten Island (NY, USA), December 8. - Sex differences in the central nervous system. Reproductive Endocrinol. Seminar and Students Seminar, Cornell, Ithaca (NY, USA), December 9. - Plasticity in the ageing central nervous system. Dept. Neurobiology and Behavior, Cornell, Ithaca, (NY, USA), December 11. - Combined research project NIBR-Cornell Lab for Pregnancy and Newborn, Cornell, Ithaca NY, USA, December 11. 130

1988 - Hersenen en menopauze. Symp. `De Medicalisering van de postmenopauze?'. Acad. Medisch Centrum, Amsterdam, March 23. - MS gezien door neuropatholoog. MS Research Studiedag (NOWOMS), Centr. Lab. Bloedtransfusiedienst, Amsterdam, March 26. - Neurobiologisch perspectief in dementie. Seminar `Dementie in Wetenschappelijk Perspectief, Konsekwenties voor de Praktijk', Helmond, April 22. - Een MS Hersenbank, NOWOMS, Nijmegen, Afd. Neurologie, October 29. - Presentation "Advice of the subgroup Tissue Banking", EURAGE Meeting on `Ageing of the Brain and Dementia', Lausanne, Switzerland, November 18-19. - Stain the human brain. Symp. Genootschap ter Bevordering van Natuur-, Genees- en Heelkunde, `Histochemistry, More than a Tool', Amsterdam, November 25. - Hoe kan een neuron veroudering/dementie overleven. Medigon-Retraite Neurowetenschappen, Veldhoven, December 1. 1989 - De klok in onze hersenen. Koninklijke Maatschappij voor Natuurkunde DILIGENTIA, Den Haag, January 30. - De geslachtelijke differentiatie van de hersenen. Amsterdamse Neurologen Vereniging, AMC, A dam. March 2. - De menselijke hypothalamus in relatie tot dementie, gender en sexuele preferentie. Wetenschappelijke bijeenkomst afdeling Infectieziekten, Tropische Geneeskunde, Immunologie en AIDS, AMC, A dam, April 13, 1989. - Presentation during the Workshop on Neuropathological diagnosis of Alzheimer's disease, Florence, May 30. - Mens sana in corpore sano. Symposium, Univ. van Twente, Enschede, September 20. - Het verschijnen en verdwijnen van concepten over veroudering. Eerste Lustrumbijeenkomst Medigondwarsverband Gerontologie, Egmond aan Zee, 23 November - Ziekte van Alzheimer: ontwikkelingen betreffende etiologie en diagnostiek. Meeting on the occasion of the 80th anniversary of the "Amsterdamsche Neurologenvereeniging", 14 December, NIBR, Amsterdam. - The human hypothalamus in health and disease. Dept. of Geriatric Medicine, Huddinge Hospital, Karolinska, Stockholm, Sweden, 15 December. 1990 - Dutch Society on Cell Biology 1959-1989: The neuron en the struggle for existence during development, aging and dementia. Attainments and Prospects - Cell Biology and Neurobiology, Nijmegen, 29-30 January. - Architecture of the human hypothalamus. Dept. of Physiology, State University Leiden, 7 February - Potentialities and pitfalls of the use of human postmortem brain material for the study of Alzheimer's disease. 24th Ann. Scientific Meeting Europ. Soc. for Clinical Investigation, Maastricht, 26 April. - The Netherlands Brain Bank: necessity for rapid obductions. Dept. of Cardiology AMC, 23 May 1990 - Debate on Pharmacotherapy of Alzheimer's Disease: Yes or no. XIth International Congress on Pharmacology, Amsterdam, 4 July 1990 1991 - 'Zien denken' NeuroSPECT-meeting, 11 January, AMC, Amsterdam - 'Hersenen in relatie tot geslacht en sexuele oriëntatie' Vereniging het Nederlands Natuur- en geneeskundig congres-meeting. Amsterdam, 25 January. - Development of the human hypothalamus in relation to birth, Guest lecture, Society for the study of fetal physiology, De Eemhof, Flevopolder, 7 May. - The hypothalamus in dementia disorders. Research education course on etiological and clinical aspects of Alzheimer's disease and vascular dementia. Dept. of Psychiatry and Neurochemistry, University of Götheborg, Sweden, 17 May. - Discussion on the Tissue Bank for Neurobiological Research: Organization, Methods and Utilization. University Hospital Uppsala, Sweden, 16 May. - Medi(c)alisering gezondheidszorg en media. MFAS lectures, Amsterdam, 21 May. - De hypothalamus bij veroudering en de ziekte van Alzheimer. Lezing voor de Interfacultaire club voor Moleculaire Neurobiologie, organized within the framework of the Groninger Centrum voor Gedrag, 131

Cognitie and in cooperation with the Biomedische Technologie Centrum, Groningen, the Netherlands, 18 September. - Markers for Alzheimer's disease. Lecture at the 7th International Meeting of Alzheimer's Disease International, Amsterdam, the Netherlands, 25 September. - Sexual Differentiation of the Human Hypothalamus in Relation to Gender and Sexual Preference. Lecture at the Eli Lilly VIII International Symposium on Endocrinology and Development. Telfs-Buchen, Austria, 12 October. - Brain Banks. Lezing voor de European Workshop on Familial Motor Neuron Disease (Amyotrophic Lateral Sclerosis-FALS). European Neuromuscular Centre, Baarn, The Netherlands, October 25-27. - The human suprachiasmatic nucleus in relation to development, aging, season and sexual orientation. Proceedings Conference Philippe Laudat: Neurobiology of circadian and seasonal rhythms - animal and clinical studies, Strasbourg, France, 25-30 November. 1992 - De hypothalamus van de mens. Lezing voor de NVE/NVDO-bijeenkomst 'Klinische Endocrinologie 1992', Doorwerth, The Netherlands, 21 februari 1992. - De ziekte van Alzheimer. Lezing voor de Donateursdag van de Alzheimer Stichting. Amersfoort, the Netherlands, 21 maart 1992. - The Human Suprachiasmatic Nucleus in Relation to Development, Aging, Season and Sexual Orientation. University of Illinois, Urbana-Champaign, USA, 4 May 1992. - TV-uitzending over De Nederlandse Hersenbank bij 'NOS-Laat', met Dr. R. Ravid, 14 mei 1992. - De sexuele differentiatie van de hersenen van de mens. Lezing voor de publieksdag van de Stichting voor Publieksvoorlichting over Wetenschap en Techniek. Onderwerp: de biologische kant van menselijk gedrag. Jaarbeurs, Utrecht, 23 mei 1992. - NIBR contribution to Amstelproject 20/10/92, Valeriuskliniek, Amsterdam, December 1992. - The human hypothalamus in Aging and Dementia. Lecture for the Scientific Symposium 'Recent Advances in the Neuroendocrinology of Aging, Ulm, Germany 13 November 1992. - Morphometry and the hypothalamus. MRC, NDB Group, Babraham, Cambridge, UK. 19 November 1992. - Colloquium 'Sexual differentiation of the human hypothalamus', Babraham, Cambridge, UK. 19 November 1992. - The human hypothalamus in health and disease. Addenbrooke's Hospital, Cambridge, UK. 20 November 1992. - De hypothalamus van de mens. Lecture for the Annual General Meeting of Members of the Genootschap ter bevordering van Natuur-, Genees- en Heelkunde. B.C.P. Jansen Instituut, Amsterdam, 27 November 1992. - Neuropeptiden in de hypothalamus van de mens. Neuropeptiden themabijeenkomst van de Afdeling Natuurkunde van de KNAW. Amsterdam, 30 November 1992. 1993 - Swaab, D.F./Lucassen, P.J. - Herstelt of voorkomt stimulatie van neuronen degeneratie tijdens veroudering en de ziekte van Alzheimer? NWO deelwerkgemeenschap 'Ontwikkeling en Veroudering van het centrale zenuwstelsel en gedrag', 15 februari 1993 - What is a good control lesion from the hypothalamus (19/3/1993, European Brain Banking in the decade of the brain, Royal Netherlands Academy of Sciences, Amsterdam, 19 March 1993. - Neuroendocrine alterations in Alzheimer's disease. International workshop: Alzheimer's disease: Progress for the next decade, 22-23 March 1993, Madrid, Spain. - Intrauterine groeivertraging en hersenontwikkeling. Symposium Perinatale aspecten van groeivertraging. Afscheidssymposium Prof.dr. P.E. Treffers, AMC, Amsterdam, 27 mei 1993. - Sexuele differentiatie van de hypothalamus van de mens. Retraite Werkgemeenschappen Ontwikkeling en Veroudering ZG en Motoriek, Kerkrade, 9 December 1993. - Neuro-endocriene regulatie van de baring. Papendalsymposium Nederlandse Vereniging voor Fysiologie "Fysiologie van de zwangerschap", 10 december 1993. - Swaab,D.F., F.C. Raadsheer, A. Salehi and J.A.P. Van de Nes - Physiological vs. pathological aging in the human hypothalamus. Sixth Congress of the International Psychogeriatric Association (IPA), Berlin, Germany, September 5-10, 1993. 1994 - Activation of corticotropine releasing hormone (CRH) neurons in MS patients. Scientific Meeting of the 132

Stichting Vrienden MS research, Amsterdam, 28 January 1994. - Functional anatomy of the human hypothalamus. Department of Anatomy of the University of Cambridge. Cambridge, UK, 3 June 1994. - The NIBR research programme and the Netherlands Brain Bank (a visit of participants of the European Summer School on Cognitive Neuroscience) Amsterdam, 29 June 1994. - De sexuele differentiatie van de hersenen van de mens. Sandoz Satelliet Symposium "New Developments in Diagnosis and Treatment of Acromegaly. The Grand Hotel, Amsterdam, 17 July 1994. - Sexual differentiation of the human brain. Tandem Day on Hormones and the Brain of the Dutch Society for Endocrinology. Amsterdam, November 2, 1994 - Plasticity in the human brain in aging and Alzheimer's disease. (not cell loss by athrophy is the main hallmark of Alzheimer's disease). Seminar at Cornell University, Ithaca, NY, USA, October 4, 1994. - Lifetime changes in the human suprachiasmatic nucleus (including circadian and circannual fluctuation in humans). Seminar at Cornell University, Ithaca, NY, USA, October 5, 1994. - De rol van cerebraal amyloid bij de ziekte van Alzheimer (is geen centrale). Controversen in de Neuropsychiatrie. Amsterdam, 14 October 1994. - Immunocytochemistry, in situ hybridization and morphometry; respect the volume. European Brain Bank Network for neurobiological studies in neurological and psychiatric disorders (E.B.B.N.). Biomed-I programme. Workshop, Thessaloniki, Greece, October 21-22, 1994. - Does the Brain Mind? Debate in De Balie, Amsterdam, 13 November 1994. - Theoretical aspects of fetal brain development, 24-hour rhythms and human parturition. Symposium "Foetale Hersenontwikkeling, 24-uurs ritmen en de menselijke baring" en "Grenzen van moderne voortplantingstechnieken". Amsterdam, 15 December 1994. 1995 - Recent hersenonderzoek in Nederland. Het Trippenhuis, 12 January 1995. - Kan activatie van het zenuwstelsel het Alzheimerproces gunstig beïnvloeden? COBO-symposium Diagnose en Behandeling van Dementieën. Beatrixgebouw, Jaarbeurs Utrecht, 20 January 1995. - The human hypothalamus "... the very main spring of primitive existence - vegetative, emotional, reproductive - on which with more or less success, man has come to superimpose a cortex of inhibition". Scientific symposium in honour of Prof. Joos Joosse, Amsterdam, 16 May. - Sexual dimorphism in the human hypothalamus. Biomed workshop, St. John's College, Cambridge, UK 1-7-95. - The Neurobiology and neuropathology of the human hypothalamus. Plenary lecture. Neurodegenerative diseases research group symposiu,, 29-06-95. Institute of Psychiatry, Mandsley Hospital, London, UK. - Sexualiteit en hersenen: water en vuur. Wetenschapsdag, 8 October 1995, Agnietenkapel, UvA. - member of the panel for the Panel Debate on the future of Sexology which concludes the exhibition on 100 Years of Sexology in Amsterdam. 12 October 1995, Agnietenkapel, UvA. - Sexual differentiation of the human brain: not by hormones alone. Vergadering NWO Werkgemeenschap "Functionele Neuronale Systemen", 1 December 1995, Stratenum, Utrecht. 1996 - Sexualiteit en Hersenen: Water en Vuur. Openingslezing van het NIBI. 10e Conferentie voor het Biologie Onderwijs, 12 Januari 1996, Driebergen. - Sexual differentiation of the human brain: relation to sexual orientation and transsexuality. Rockefeller University, N.Y., USA, 10-2-1996 (Drs. B.S. McEwen and D.W. Pfaff). - Neuronal inactivity as a major hallmark of Alzheimer's disease. European Brain Bank Network (EBBN) Workshop. Fifth European Congress of Neuropathology. Paris, April 27, 1996. - Sex and Stress: post-mortem human brain studies. Elba International Neuroscience Programme, Workshop and Summer School, 1996. - The human hypothalamus. Age-related degeneration in the brain centers of sex, rhythms and emotions and opportunities for reactivation. Festvortrag des Emil Kraepelin Gastprofessors 1996. Max-Planck Institut für Psychiatrie, Munich, Germany, 28 Nov. 1996. 1997 - De klok van de veroudering en veroudering van de klok. Tijd & Leven. Lezingencyclus Teyler s Museum, Haarlem. 11 Jan. 1997 - Prader Willi syndroom, een ziekte van de hypothalamus. Rondetafelconferentie Prader Willi syndroom: wetenschappelijke stand van zaken en prioriteiten. 14 March 1997. - Neurobiologische systemen betrokken bij depressie. Lezingencyclus Ontwikkelingen in de psychiatrie. 133

Universiteit Maastricht. 16 april 1997. - Aging and the brain. Use it or lose it? First Neuro-Endo Meeting. Nederlandse Vereniging voor Endocrinologie. Doorwerth, June 2-4, 1997. - Depressie bij ouderen - State of the Art. Symposium Depressies en Gedragsstoornissen bij Ouderen. Psychiatrisch Centrum Bloemendaal, 6 June 1997. - Normal and pathological aging of the human circadian system. XVI World Congress of Neurology. Buenos Aires, Argentina, 14-19 September 1997 - Groot en klein in de hersenen. Wetenschapsdag 1997, 5 October 1997. - De rol van de biologie in de psychiatrie; hoe buigzaam is ons brein? 10 Jaar Psychiatrie. Een proloog voor de toekomst. Scheveningen, 7 and 8 November 1997. - How abnormalities of brain function can be investigated in postmortem material. 7th Scientific Meeting of the Society for the Study of Behavioural Phenotypes (SSBP). Cambridge, UK, 14 November 1997. 1998 Key lectures - Reduced neuronal activity as the major cause of dementia in Alzheimer s disease: therapeutic strategies for reactivation. lecture 6 th International Conference on Alzheimer s disease and related disorders, Amsterdam (18-23 July 1998). - Depression in Alzheimer s disease. National Chinese Conference on Senile Dementia and Depression, Beijing, PR China, 14-16 November 1998. Plenary lectures - Brain peptides in human diseases. IV European Congress of endocrinology. Seville, Spain, 1998, L2. - The hypothalamus in Prader-Willi syndrome. 3 rd Prader-Willi syndrome conference. Lido di Jesolo, Italy, 1998. Invited lectures - Sex and gender differences in the human brain: behavioral consequences. Forum of European Neurosciences, Berlin, Germany, 27 June- 1 July 1998. - Postmortem studies of the locus coeruleus and hypothalamus in depression. Aging 2000, Munich, Germany, 1998 - Reduced neuronal activity and reactivation in Alzheimer s disease. XIth Congress of the European College of Neuropsychopharmacology. Paris, France, Oct. 31-Nov. 4, 1998. Lectures - Symposium Psychoanalyse en Neurobiologie. Lecture Hogere functies in lagere regionen. July 1998, Artis, Amsterdam. - Prader-Willi Syndroom invitational conference. Wetenschappelijke stand van zaken en prioriteiten. Medische Aspecten: Hypothalamus in PWS. NIBR, 1 October 1998. - Perspectives in Alzheimer s Research, Xuanwu Hospital, Beijing, PR China, 12-11-1998 - Plasticity in Alzheimer s disease. Military Institute of Medical Sciences, Beijing, PR China, 13-11-1998 - Opportunities for a Chinese Association for Alzheimer s Research. During the National Chinese Conference on Senile Dementia and Depression, Beijing, PR China, 16 November 1998. - Het onderzoeksprogramma van het Nederlands Instituut voor Hersenonderzoek; het belang van obducties. Stafbespreking MFO Psychiatrie, AMC 30-11-1998. Public lectures - Hersenonderzoek, emoties en ethiek. K.L. Poll-stichting voor Onderwijs, Kunst en Wetenschap, Paradiso, 29-3-1998, Amsterdam. 1999 Key lectures - Prader-Willi syndrome. 7 th Australasian Prader-Willi syndrome conference, Life, live it to the full. Melbourne, Australia, March 1999 Invited lectures - Decreased neuronal activity and neuronal reactivation in Alzheimer s disease. The 204 th Neuroscience Seminar of Kyoto Prefectural University of Medicine, Kyoto, Japan, 9 July 1999. - Sexual differentiation of the human hypothalamus. ESHRE 15 th Ann. Meeting, 27-30 June, Tours, France. - Sexual differentiation of the human hypothalamus. 22 nd Annual Meeting of the Japan Neuroscience Society, Osaka, Japan, 6-8 July, 1999. Lectures - Geestelijke volksgezondheid, de hersenen en verstandelijke handicaps. Lezing voor de Skövde groep, 134

4 March 1998. - Morphology: Decreased neuronal metabolism in Alzheimer s disease: potential for reactivation, European Alzheimer s Research Symposium, Maastricht, 17 September 1999. - Successful aging and the struggle against dementias. International Symposium on Medicine and Pharmacology, Prevention and Treatment of Senile Diseases. Beijing, P.R. China, 17 October 1999. - Medicine and psychology in the future. The Future of Psychology congress 1999, Amsterdam, 11 November. - Licht van luier tot wandelstok. Symposium Licht en Gezondheid., Amsterdam, 16 November 1999. - Partogenese, neuropathologie en therapie van schizofrenie: Het belang van de Nederlandse Hersenbank. Ypsilon, Zaandam, 17 December 1999 - Neuropeptides in brain aging and Alzheimer s disease. London, UK. - Successful aging and the struggle against dementias. 99 International Symposium on Medicine and Pharmacology. Prevention and Treatment of Senile Diseases. Public lectures - Is er leven na de (hersen)dood? Hersenen en Bewustzijn, OKW Wetenschapslezingen in Paradiso. Amsterdam, 9 May 1999. - Hersenen op Leeftijd. Jubileumdag Hersenstichting Nederland, Utrecht, 19 June 1999. 2000 Special lectures - David de Wiedlezing. Alzheimer onderzoek, het begin van een beter einde., 14 april 2000. Theatronzaal, Educatorium, Utrecht. - Federaprijs lezing. Dementie: Het weinige dat wij weten over het ontluisterend vergeten.. Rai Congrescentrum Amsterdam, 17/18 november 2000. Key lectures - Reduced neuronal activity and reactivation in Alzheimer s disease. 2 nd National Meeting on Dementia and Depression & International Symposium on Alzheimer s Disease. TunXi, May-June, 2000 - Endocrinology of Memory. Ice 2000, Sydney, Australia, 29 October-2 November 2000. Invited lectures - Neuropathology of the hypothalamus and Alzheimer s disease (AD), XIIIèmes journées dy gral France Alzheimer, Neuro-Endocrinologie des démences: Hormones, Plaisir, Vieillissement. 27-28-29 January 2000, Marseille, France. - The hypothalamus in multiple sclerosis: changes in the paraventricular nucleus.12th MS Forum Workshop, Athens, Greece, 17-19 March 2000 - Interaction between the prefrontal cortex and the hypothalamus in depression. Department of Psychiatry, National and Kapodistrian University of Athens, Greece, 17 March 2000. - Male-female differences in brain morphology and biology. Second Amsterdam Menopause Symposium, April 2000. - Herstel van functie door stimulatie van hersencellen: ontwikkeling in de neurologie en psychiatrie. Studiedag Vrije Universiteit Amsterdam over Multimodale interventies bij kinderen met Attention Deficit Hyperactivity Disorder (ADHD) en patiënten met de ziekte van Alzheimer (AD). 6 April 2000. - Eating, drinking, sex and thinking; the molecular anatomy of the human hypothalamus. Lustrum Faculteit Biologie Vrije Universiteit. Amsterdam, 4 oktober 2000. - The human hypothalamus in relation to age, sex and sexual orientation. Trabajos del Instituto Cajal, Madrid, Spain. - Sex differences in the human brain. King s College Meeting of the Physiological Society, London, UK. Lectures - Verminderde neuronale activiteit en reactivatie van neuronen bij de ziekte van Alzheimer. NPA seminar, AMC. Amsterdam, 23 maart 2000. - Dutch brain bank and schizophrenia. Solvay Mini-Symposium on Target Discovery for Schizophrenia using human brain tissue. May 2000. - Meet-the-Professor sessions. Second Amsterdam Menopause Symposium, April 2000. - Het knappe maar kwetsbare kopje van het nog ongeboren kind. Gynaecongres Lecture 2000. Millennium Gynaecongres, Jaarbeurs Utrecht, May 2000. - Verminderde neuronale activiteit en reactivatie van neuronen bij de ziekte van Alzheimer. NPA Seminar, AMC, March 2000. - Hersenen, bewustzijn en geloof: neurobiologische aspecten. Symposium Thijmgenootschap en Heyendaal Instituut Nijmegen, gehouden in hotel Krasnapolsky in Amsterdam, op 30 september 2000. 135

2001 Plenary lectures - 51 st Asian Federation of Endocrine Societies congress: Recent advances in neuroendocrinology: the role of the suprachiasmatic nucleus in circadian rhythms. Bali International Convention Center, Indonesia, 8 November Invited lectures - Hersenen, bewustzijn en geloof: neurobiologische aspecten. In het diepst van mijn gedachten. Hersenen, bewustzijn en het zicht op onszelf. Symposium van het Thijmgenootschap en Heyendaal Instituut, Nijmegen. 27January 2001. - What makes a man? Lecture for the Meeting of the Dutch Endocrinology Society (NVE) and the NVDO on 9 February 2001. - Sexuele differentiatie van de hersenen. Tegelaers-lezing, Emma Kinderziekenhuis AMC, 16 February 2001. - Endocrinology of memory. 5 th International Conference on Progress in Alzheimer s and Parkinson s disease. Kyoto, Japan, March 31-April 5. - Sexual differentiation of the human hypothalamus. Fifth Dutch Endo-Neuro Meeting, Doorwerth, 5-7 June. - The Biological Clock and Alzheimer's disease. Koninklijke Nederlandse Dierkundige Vereniging. 20 april, Amsterdam, VU. - Neurobiologie van depressie (Neurobiology of depression). Nederlandse Vereniging v. Psychiatrie. Groningen, 3-5 April. - Seminar Neurodegeneration, in particular Alzheimer s disease. First Military Medical University (Prof. Tian-Ming Gao) Guangzhou, P.R. China, 1 November. - Alzheimer s disease. Course of Neuro- and Molecular biology, Jakarta, Indonesia, 4 November. Three Lectures: Brain development and functional teratology; Alzheimer s disease; Neurobiology of schizophrenia. Lectures - Brain aging and Alzheimer s disease (AD): Use it or lose it. 22 nd International Summer School of Brain Research, Amsterdam, 20-24 August. - Introduction to C.U. Ariëns Kappers Lecture, 22 nd International Summer School of Brain Research. Amsterdam, 20-24 August 2001. - Seminar Development and Neurodegeneration, use it or lose it,capital University of Medical Sciences, Beijing Institute for Neuroscience (Prof. Xu Qun Yuan), Beijing, P.R. China, 22 October. - Masterclass Anhui Medical University, Dept. Neurobiology (Prof. J.N. Zhou), Hefei, P.R. China, 25 October - Seminar Programming and plasticity of the brain. Anhui Medical University, Hefei, P.R. China, 25 October - Seminar Life-time structure-function relationships of the human suprachiasmatic nucleus. Univ. Science Technology, Hefei, P.R. China, 26 October - Brain development and functional teratology. Course of Neuro- and Molecular biology. Jakarta, Indonesia, 4 November. - Introduction: Restimulation of Alzheimer neurons as aim. Symposium NIBR, 12 December Public lectures - Het Brein - een hoofdzaak. Openingslezing voor tentoonstelling Het Brein in Museum Naturalis in Leiden, 1 maart 2001 - Wij zijn onze hersenen. Zondaglezing ter gelegenheid van de tentoonstelling Het Brein in Museum Naturalis in Leiden, 22 april 2001. - Theorieën van hersenveroudering. Brein Publieksdag Hersenwerk 2002. Jaarbeurs Utrecht, 18 oktober 2001. - Wij zijn onze hersenen. Studium Generale, Maastricht, 2 October - The hypothalamus in Prader-Willi syndrome. 10. Tagung Prader Willi Syndrom Vereinigung Deutschland. Reutlingen, Germany, 16 November. - Symposium Verknipt of Verlicht. Verknipt of Verlicht: het blijft neurobiologie. Rotterdam, 14 December. 2002 Key lectures - The role of the hypothalamus and endocrine systems in sexuality. Society for the Scientific Study of Sexuality, 2002 Midcontinent and Eastern region conference. Ferris State University, Big Rapids, Michigan, 14 juni 136

- Sex differences, stages of life, and neuropsychiatric disease. Society for the Scientific Study of Sexuality, 2002 Midcontinent and Eastern region conference. Ferris State University, Big Rapids, Michigan, 15 June - Nuclear receptors in human postmortem brain. Karolinska Institute, Huddinge, Sweden, 25 August. - Onze levensloop is die van onze hersenen: ontwikkeling, seksuele differentiatie, veroudering, en de ziekte van Alzheimer. Startsymposium NWO programma Cognitie. Tussen Brein en Bewustzijn. Wetenschapsmuseum NEMO, 1 november 2002. Invited lectures - State of the art: hypothalamus en veroudering. Nederlands-Vlaamse Vereniging voor Impotentie Onderzoek (NVIO) 15e jaarcongres Vught, 11 januari 2002. - Hersenen, bewustzijn en geloof: neurobiologische aspecten. Lezingenserie: Religie in de academische arena. Studium Generale Universiteit Leiden i.s.m. Faculteit der Godgeleerdheid. 18 februari 2002. - Introduction: Sexual differentiation of the human brain. Expert Workshop The Brain and Behaviour in different stages of human life. International Health Foundation, Wassenaar, 18/19 april 2002. - Fetal programming of the brain. Symposium: Fetal Origins of Adult Disease. AMC, 15 mei 2002. - Discussion: Procurement & Dissemination of Human Brain Tissue. Neuroscience Seminar Series, Yerkes Primate Research Center, Emory University, Atlanta, GA, USA, 10 June - Sexual differentiation of the human brain. Neuroscience Seminar Series, Yerkes Primate Research Center, Emory University, Atlanta, GA, USA, 10 June. - Alzheimer s disease: therapeutic strategies towards restimulation of neuronal metabolism. Yerkes Primate Research Center, Emory University, Atlanta, GA, USA, 11 June. - The human circadian system in health and disease. Symposium: The Circadian Clock (in honour of the superannuation of Prof. Dr. W.J. Rietveld. Leiden, 29 November 2002. - Hoe verstoren wij de hersenontwikkeling van onze kinderen? Alumnidag 2002, Medische Alumnivereniging Antonius Deusing. 2 november 2002, AZ Groningen. - Hersenveroudering en de ziekte van Alzheimer. Koninklijke Vlaamse Academie van België voor Wetenschappen en Kunsten (KVAB), Brussel, België, 25 oktober 2002. - Light and the Elderly. Light and Health Research Foundation. Symposium Healthy Lighting. 20 november 2002, Eindhoven University of Technology. - Herstel van functies bij veroudering en de ziekte van Alzheimer. Symposium Neurorevalidatie bij dementie: realtiteit of utopie? Vrije Universiteit, Amsterdam, 13 december 2002. - Neuroendocrinology of memory in Alzheimer s disease. Alzheimer Conference Stockholm, Sweden. July 2002. Lectures - Regulation of appetite and eating behavior in the central nervous system. Prader Willi syndrome: new perspectives. Dutch Growth Foundation, Amersfoort, 11 januari 2002. - De pathogenese van de ziekte van Alzheimer. Refereeravond Stichting Meerkanten. Ermelo, 7 januari 2002. - Prader-Willi syndroom: een hypothalaam ziektebeeld. Bijeenkomst met als doel het genereren van nieuwe samenwerkings- en onderzoeksideeën m.b.t. de rol van de hypothalamus in episodische hersenaandoeningen. NIH en LUMC, 10 januari 2002. - Use it or lose it. Gezond ouder worden in een verrijkte omgeving. AMC, 16 april 2002. - Hypothalamic disorders: lessons from postmortem material. Hypothalamus Werkgroep Amsterdam (HWA), Conferentie Noorderbuiten, 29 mei 2002. - Therapeutic strategies for Alzheimer s disease: focus on neuronal degeneration. Symposium Current Challenges, Emerging Treatments. Eight International Conference on Alzheimer s Disease and Related Disorders, Stockholm, Sweden, 23 July. - Schizofrenie en de Nederlandse Hersenbank. Ypsilon Symposium, UMC, Utrecht, 30 augustus. Public lectures - Zijn wij onze hersenen of worden we meer dan dat? Discussie: Hersenen in de Geneeskunde, AMC, 7 maart. Samen met Dr. J.A. Swinkels. - Ouder worden met een intact brein? 6e Nationaal Gerontologiecongres. Ouder worden, nu en straks. 6e Nat. Gerontologie Congres, Veldhoven, 8 maart. - Oud worden met een intact brein? Publieksdag Weten van Vergeten. Alzheimer Nederland Symposium, Maastricht, 3 juni. - Schizofrenie: een ontwikkelingsstoornis. Invitational Conference Stichting Voorbereiding Acomplex, Almere, 5 september. - Willens en Wetens. Forumdiscussie over de vraag of de natuurwetenschappen ruimte bieden voor een vrije wil. Interdisciplinair Studie Forum, 16 november 2002, Amsterdam. 137

2003 Special lectures - Opening lecture Research Institute. Functional alterations in postmortem tissue of patients suffering from Alzheimer and depression. Euron Recognition, Research Institute Brain and Behaviour, Maastricht, 24 September 2003. - Hersenonderzoek: kinderspel. Wetenschapsdag AMC, 19 October 2003. (Lecture for an audience of children). Key lectures - Functionele teratologie: permanente gevolgen voor de hersenontwikkeling van het kind. Minisymposium 23 mei. Kinderen in de Toxicologie. Sectie Toxicologie en Risicobeoordeling. Universiteit van Utrecht, Faculteit Diergeneeskunde. - Permanente gevolgen van gebeurtenissen in de vroege ontwikkeling. 3de EKZ wetenschapssymposium. Koninklijk Instituut voor de Tropen (KIT). Invited lectures - Human post-mortem studies. Workshop stress hormones and depression. In honour of Prof. dr. dr. Florian Holsboer, recipient of the 2002 Marius Tausk Chair in Endocrinology. 20-21 January, Oegstgeest - Placebo-effecten zijn ook echte effecten. Co-assistentenraad, UvA, OLVG, 27 March - Sex, mood and food and the human hypothalamus. XXXII Annual Congress of the International Society of Psychoneuroendocrinology (Pisa, Italy, 23 March). - Estrogens; their action on the human brain. 3 rd Pisa Workshop Hormone Replacement Therapy in Climacteric and Aging Brain. Pisa, Italy, 16 March. - Reactivation of metabolically affected neurons in Alzheimer s disease. Symposium at the IGSN, Ruhr University, Bochum, Germany, 18 August 2003. - Re-activation of neurons in Alzheimer s disease. RIDE Research Meeting, Rotterdam, 16 December 2003 Lectures - The hypothalamus in Parkinson s disease. On the occasion of Hagai Bergman s research group Interdisciplinary Center for Neural Computation from the Hebrew University, Jerusalem, Israel. 23-24 January, Netherlands Institute for Brain Research. - Presentation Netherlands Institute for Brain Research at the one-day-get-together for scientific staff of the Research School ONWA at The Second Decade of ONWA, 11 April 2003 - Chair of discussion on The preclinical-clinical alliance at the one-day-get-together for scientific staff on ONWA at The Second Decade of ONWA, 11 April 2003. - The application of a new model for the study of Alzheimer s disease: human post-mortem slices in tissue culture. Workshop Findings from Awarded Alzheimer s Research Projects. ISAO Symposium, 2 October, Brussels, Belgium - Bewustzijn, hersenen, en de kliniek. Symposium Evolutie en Bewustzijn. Faculteitsvereniging Gyrinus Natans, Vrije Universiteit, Amsterdam, 28 October 2003. - Geheugen in een ouder brein. Alzheimer Publieksdag, Utrecht, 30 October 2003. Public lectures - Seksuele differentiatie van onze hersenen. Nederlandse Vereniging voor Seksuologie, sectie hulpverlening. Planetarium Gaasperplas, Amsterdam, 26 March. - Is er leven na de (hersen) dood? Thomas More Lecture, Studiekring Thomas More, Maastricht, 20 May 2003. - Waarheen? Vergezichten in de wetenschap: het brein The Final Frontier, over de stand van zaken van het hersenen-en-bewustzijn onderzoek. Paradiso lezing, OKW/NWO, Paradiso, Amsterdam, 24 June 2003. - Schizofrenie. Minder gek dan je denkt. Nationale Dag voor de Geestelijke Volksgezondheid, Riagg Zaanstreek-Waterland, Hersenonderzoek naar schizofrenie. 10 October 2003. - Effecten van het materialistisch denken op ons mensbeeld. Programme RRQR-congres, Christelijke Hogeschool Ede, 8 November, 2003 (public debate). 2004 Invited lectures - How important are prenatal and postnatal environment in the determination of gender identity and gender role? Academy Colloquium Prenatal programming of behavior, physiology and cognition, 20 February 2004, KNAW, Amsterdam 138

- Sex differences in the human hypothalamus: androgen and estrogen receptors in sexual differentiation, adulthood and Alzheimer s disease. Androgen Receptors: no longer the illegitimate cousin of ER. 2004 Workshop on steroid hormones and brain function. Breckenridge, Colorado, USA, March 29, 2004. - The human hypothalamus in health and disease: sex, mood and food. Colorado State University, Fort Collins, USA, 31 March 2004 - The human hypothalamus in health and disease. May 7, 2004, Dept. Neuroscience & Physiology and SUNY Upstate Medical University. - De ontwikkelingsneurobiologie van emoties, stemming en gedrag. Symposium De Bascule. Kwestie van Gevoel. 18 juni 2004, AMC - The neurobiology of depression. Inst. Nacional de Psiquiatria Ramon de la Fuente Muñiz (Dir. Prof. G. Heinze), Mexico City, Mexico. 26 July 2004. - Sexual differentiation of the human brain. Dept. Pharmacology and Toxicology, Cinvestan, Director Prof. Dr. A. Fernandez-Guasti, Mexico City, Mexico, 27 July 2004. - The neurobiology of eating disorders. Inst. de Fysiologia B.U.A.P. (Dir. Prof. J.R. Equibar). Publa, Mexico. - Sexual differentiation of the human brain: relation to gender and sexual orientation. Annual Meeting British Society for Neuroendocrinology, Univ. of Glasgow, 6-8 September, 2004. - Reactivation of neurons in Alzheimer's disease. 2nd Int. Congress on Neuroregeneration, Rio de Janeiro, Brazil, September 20-24, 2004 - The stress-axis in Alzheime's disease. 2nd Int. Congress on Neuroregeneration, Rio de Janeiro, Brazil, September 20-24, 2004 - Is er leven na de (hersen)dood?. Unitas, Amstelveen, 5 oktober 2004. - The Human Hypothalamus in Health and Disease. 7th Annual Symposium of the Center for Neuroendorcine Studies "Neuroendocrinology; from bench to bedside and back". Univ. Massachusetts, Amherst, MA, USA, 8 October 2004. - The stress-axis in Alzheimer's disease. II International Congress on Neuroregeneration. Rio de Janeiro, Brazil, September 20-24, 2004. - Steroid hormone receptors and the human brain. Their role in development, aging and Alzheimer s disease. Organon (Akzo Nobel) Oss, 11 November 2004 - Hypothalamic defects and brain banking in PWS. Prader-Willi syndrome association (USA) Research Advocacy Team. Baltimore, USA, 19 November 2004 - Hypothalamic NPY, AGRP and GH in relation to disease duration. Minisymposium for Spinoza Professor (G. van den Berghe) The hypothalamus and (critical) illness, NIH, Amsterdam, 14 December 2004 - We are our brain. Sterrenkundig Instituut Anton Pannekoek, Amsterdam, 17 December 2004 (Prof. dr. E. van den Heuvel) Special lectures - Granuloompjes. On the occasion of Dr. C.M. Roos' retirement from the AMC lung disease department, 3 June 2004 - Sexual differentiation of the human brain; development aging and Alzheimer s disease. Purdue University, West Lafayette, USA, 5 May 2004 - The human hypothalamus: sex, drinking, mood and food. Purdue University, West Lafayette, USA, May 6. - Introduction to the Project: Samen tegen Parkinson (Together against Parkinson). Stichting Vrienden van de Hebreeuwse Universiteit van Jeruzalem/Hebrew University Netherlands Association. 17 June 2004, Hilton Hotel Amsterdam. Key lectures - Postmortem brain research in PWS. International PWS Conference, Christchurch, New Zealand, 9-12 April 2004. - Hypothalamic pathophysiology in PWS. International PWS Conference, Christchurch, New Zealand, 9-12 April 2004. - The human hypothalamus in health and disease. La Sociedad Mexicana de Ciencias Fisilologicas. XLVII Congreso Nacional de Ciencias Fisiologicas, Veracruz Ver. 1-5 August 2004. Dir. Dr. Luisa Rocha. - Reactivation of neurons in Alzheimer's disease. II International Congress on Neuroregeneration. Rio de Janeiro, Brazil, September 20-24, 2004. Plenary lectures - Steroid hormones and receptors in the human brain: involvement in development, gender disorder, aging and dementia. 11 th World Congress of Gynecological Endocrinology. Florence, Italy, Feb. 26-29, 139

2004. Lectures - Lessons from postmortem material. Hypothalamus Werkgroep Amsterdam (HWA). Free University, Amsterdam, 23 April 2004. - Introduction: repair and/or destruction. Neuroscience and Vision Symposium on Stem cells and human brain cultures: pilots and plans. IOI/NIH, Amsterdam, 4 February 2004. Public lectures - Wij zijn onze hersenen. Verenigde Protestantse Gemeente (Prof.dr. J. Lever), Amsterdam, 12 oktober 2004. - De ziekte van Alzheimer. 20-jarig bestaan Alzheimer Nederland. Frascati, Amsterdam, 24 oktober 2004. - Alleen hersenen. Studium Generale cyclus Sociale Wetenschappen, Universiteit van Utrecht. Het kind als spiegel van de beschaving, 26 October 2004. - De neurobiologie van bewustzijn, leven en dood. Genootschap voor de Joodse Wetenschap in Nederland. Amsterdam, 14 november 2004. 2005 Invited lectures - Sexual differentiation of the human brain and gender. Wetenschapsdag. Neuroscience; het grijze mysterie Faculteit Geneeskunde, Katholieke Universiteit Nijmegen, 12 January 2005. - Sex in the brain. Erasmus MC Lectures on Endocrinology. Erasmus MC, University Medical Center Rotterdam, 27 January 2005. - Neuronal reactivation in Alzheimer s disease. Two-day symposium Frontal lobe functioning: fundamentals and interventions. Faculty Psychology and Educational Science, Free University, KNAW Amsterdam, 7/8 April 2005 - Sexual differentiation of the human brain. New Frontiers in Neonatology, A Globul Forum for Research and Science, Innsbruck, Austria, Feb. 28-March 2, 2005 - Reactivation of neurons in Alzheimer s disease. Rush University Medical Center, Chicago, IL, USA, 21 April 2005 - Is sexual dimorphism of the brain plastic? Nobel Mini Symposium, Karolinska Institute, Stockholm, Sweden, 23 May 2005. - Hypothalamic alterations in Prader-Willi syndrome (PWS): focus on the orexin system. Symposium Orexins/Hypocretins, Dusseldorf/Cologne, 20-24 July 2005 - Sex differences in the human brain in relation to behaviour, gender, sexual behaviour. Symposium on Integrative Biology of Reproductive and Social Behaviors. Saint Remy Les Chevreuses, 6 October 2005 - The human circadian system in neurological and psychiatric disorders. Amsterdam-China Symposium: The Biological Clock: From Genes to Chronotherapy. Academic Medical Center, Amsterdam, 10 October 2005 - Degeneration and reactivation of metabolically impaired neurons in Alzheimer's disease. Capital Medical University, Beijing, P.R. China, 27 October 2005 - Degeneration and reactivation of metabolically impaired neurons in Alzheimer's disease. Military Medical Institute, Beijing, P.R. China, 28 October 2005 - Pathophysiology of the brain in PWS. Prader-Willi Syndrome Conference, Beijing, P.R. China, 1 November 2005 - We are our brain. Humanities College of Zhejiang University, Hangzhou, P.R. China, 4 November 2005 - We are our brain. USTC, Hefei, P.R. China, 8 November 2005 - Our brain as a target for Western and Traditional Chinese medicine, Dept. TCM and Dept. Neurobiology of the 2 nd Military Medical University, Shanghai, P.R. China, 10 November 2005 - Masterclass. First Affiliated Hospital of Medical College of Zhejiang University, Hangzhou, P.R. China, 5 November 2005 Masterclass, USTC, Hefei, P.R. China (with Dr. Jiang-Ning Zhou), 7 November 2005 - Discussie in Rode-Hoed Wetenschapscafé, 29 November 2005 Lectures - Why are some of us susceptible and others resistant to brain diseases? The possible contribution of polymorphisms. Neuroscience and Vision Symposium on Gene polymorphisms in Alzheimer s disease and multiple sclerosis (MS). NIH/IOI, Amsterdam, 26 January 2005 - Korte toelichting op het programma. ISAO, Een nieuw licht op de ziekte van Alzheimer. NIH, 23 September 2005 - Reactivatie van hersencellen bij de ziekte van Alzheimer: leven na de dood. ISAO, Een nieuw licht op de ziekte van Alzheimer. NIH, 23 September 2005 140

- U kunt iets doen tegen dementie: donor worden. ISAO, Een nieuw licht op de ziekte van Alzheimer. NIH, 23 September 2005 Public Lectures - 3 lezingen/debatten op het grensvlak tussen hersenonderzoek, maatschappij en kliniek (AMC) - Bederven wij de hersenen van onze kinderen reeds voor hun geboorte? 1 February 2005. - Seksuele differentiatie van de hersenen - wat te doen in geval van twijfel. Debat met Prof. dr. Hugo Heymans. 2 February 2005 - Het brein als dader. Debat met Prof. dr. Theo Dorelijers. 3 February 2005. - Discussieavond Opzij, 8 March, Felix Meritis, Amsterdam - What you always wanted to know about your granulomas, but were afraid to ask. General Members Meeting Sarcoidosis Association (Sarcoidose Belangenvereniging Nederland). Driebergen, 2 april 2005 - Participant in discussion on male-female differences. Magazine Opzij, 8 March 2005 - Seksualiteit, maakbaar of ongenaakbaar? Young & Out, Studium Generale, Univ. Tilburg, 14 April 2005. - Hersenen van doden zijn van levensbelang. Presentation Annual General Meeting Clients family council Clifa, Evean Oostergouw, Zaandam, 28 April 2005 - MS onderzoek en de Nederlandse Hersenbank, Publieksdag Stichting MS Research, Koepelkerk Amsterdam, 30 March 2005. - Hersenveroudering. Hoe maken we er het beste van? Rosa Spierhuis, Laren, NH, 9 June 2005 - Hersenonderzoek, een zoektocht naar onszelf. Universiteitsdag 2005, Universiteit van Amsterdam, 11 June 2005. - Lezing over de stelling: 'Opvoeding en omgeving hebben slechts een geringe invloed op de mens en de meeste van onze eigenschappen zijn aangeboren' (Charles Darwin). Oudemanhuispoort, Amsterdam, 13 October 2005. - Debat met Prof. Roel Verheul over 'Opvoeding en omgeving hebben slechts een geringe invloed op de mens en de meeste van onze eigenschappen zijn aangeboren' (Charles Darwin). Oudemanhuispoort, Amsterdam, 13 October 2005. - Sex differences in the human brain in relation to behaviour, gender, sexual orientation and brain diseases. Symposium on "Integrative Biology of Reproductive and Social Behaviors". Saint-Rémy les Chevreuses, France, 8 October 2005 2006 Invited lectures - Man/vrouw: competitie of samenwerking tussen androgenen en oestrogenen. T.g.v. de opening van de vernieuwde polikliniek Urologie en Verloskunde & Vrouwenziekten, Erasmus MC Rotterdam, 11 January 2006 - Sex differences in the human brain and gender. 16 th Medisch Interfacultair Congres 'Het Brein Ontrafeld', Delft, 4 March 2006. - Wij zijn onze hersenen. Olo, Dies, Het Amsterdams Lyceum, Amsterdam, 11 February 2006 - Wij zijn onze hersenen. Persoonlijkheid, dat ben jij. Beevee's Symposiumcommissie, Universiteit Utrecht. - Wij zijn onze hersenen. Natuurwetenschappelijke Studievereniging Amsterdam, 26 April 2006 - Nieuwe onderzoekstechnieken maken het mogelijk informatie te krijgen over het functioneren van de hypothalamus en inzicht te krijgen over ziekteprocessen in de hypothalamus. Symposium Nederlandse Hypofyse Stichting, Amsterdam, 13 May 2006 - Sekseverschillen in agressief en crimineel gedrag. 34 ste Voorjaarscongres van de Nederlandse Vereniging voor Psychiatrie. Groningen, 5 April 2006. - Wij zijn onze hersenen. Natuurwetenschappelijke Studievereniging Amsterdam, 26 April 2006. - Neuro-Theology: Demasque of religion. World Psychiatric Association International Congress. Psychiatry: Uniqueness and Universality. Istanbul, Turkey, 12-16 July 2006 - De kwab van Swaab. Genius bijeenkomst, De Waag, Amsterdam, 29 July 2006 - Sex of the human brain. 2 nd International Symposium on Disorders of Sex Development (DSD). Lübeck, Germany, 1 September 2006 - Sexual differentiation of the human hypothalamus. 12 th International Congress on Hormonal Steroids and Hormones and Cancer, Athens, Greece, 13-16 September 2006 - Sekse en genderdifferentiatie van het brein: een neurobiologisch en levensloop perspectief. Seksuologisch Lustrumcongres 2006, Antwerp, Belgium, 29 September 2006. - The hypothalamus in PWS. Meeting of the basic science and clinical research groups, European PWS research consortium, Marseille, France, 5 October 2006 - Advanced aging and Alzheimer's disease in PWS. Meeting of the basic science and clinical research groups, European PWS research consortium, Marseille, France, 6 October 2006 141

- Estrogen, xenoestrogen and sexual identity. Eighth European Meeting Days of the French Society of Gynaecology, 12-14 October 2006, Paris, France - Geslachtsverschillen in onze hersenen en hun consequenties. Maagdenhuis op Maandag. Maagdenhuis, Universiteit van Amsterdam, 16 October 2006. - Sex differences in the human brain, normal and irregular. 12 th Meeting of the European Neuroendocrine Association, Athens, Greece, 23 October 2006 - What is wrong with the hypothalamus? 2 nd Expert Meeting "Comprehensive Care of Patients with PWS - consensus, questions and future directions, Toulouse, France, 27 October 2006 - Degeneration and reactivation of metabolically impaired neurons in Alzheimer's disease. 4 th Vienna Biocenter PhD student symposium "Timing Age", Vienna, Austria, 3 November 2006 Lectures as visiting Professor - Sleep disorders in Alzheimer's disease and light therapy. Stanford, Palo Alto, Menlo Park Division, CA, USA, 23 February 2006. - The human hypothalamus in health and disease. Stanford, CA, USA, 24 February 2006. - Alzheimer's disease: early changes and neuronal activation. Dept. of Neurobiology, Second Military Medical University, Shanghai, P.R. China, 14 November 2006 - Human brain dissection: relation to function and pathology (3 hours). With Prof. J. Luo, Zhejian University School of Medicine, Hangzhou, P.R. China, 16 November 2006 - Sexual differentiation of the human brain. With Prof. J. Luo, Zhejian University School of Medicine, Hangzhou, P.R. China, 16 November 2006 - Alzheimer's disease: risk factors and targets for therapeutic strategies. With Prof. J.N. Zhou, University of Science and Technology of China, Hefei, P.R. China, 20 November 2006 - Human brain dissection: relation to function and pathology (3 hours). With Prof. J.N. Zhou, University of Science and Technology of China, Hefei, P.R. China, 21 November 2006 - Development of our character. With Prof. Cheng. Beijing Proteomic Center, Zhong Guan Cun Scientific Park, Beijing, P.R. China, 23 November 2006 - Neurobiology of depression. With Prof. Chang, Beijing Proteomic Center, Zhong Guan Cun Scientific Park, Beijing, P.R. China, 23 November 2006 - Neurobiology of depression. With Prof. Li, Dept. of Pharmacology, Capital University of Medical Sciences, Beijing, P.R. China, 24 November 2006 - Alzheimer's disease: early alterations and reactivation. With Prof. Li, Dept. of Pharmacology, Capital University of Medical Sciences, Beijing, P.R. China, 24 November 2006 Lectures - Sekseverschillen in de psychiatrie - het laatste nieuws over de neurobiologie. 34 ste Voorjaarscongres van de Nederlandse Vereniging voor Psychiatrie. Groningen, 5 April 2006. Public Lectures - Wie ben ik? Waar ben ik? Geheugen, dementie en identiteit. Salon rond Hersenschimmen, Stadsschouwburg, Amsterdam, 6 May 2006. - Nieuwe onderzoekstechnieken maken het mogelijk informatie te krijgen over het functioneren van de hypothalamus en inzicht te krijgen over ziekteprocessen in de hypothalamus. Symposium Nederlands Hypofyse Stichting, RAI Forumcentrum, Amsterdam, 13 May 2006. - Debate (Van Lommel-Swaab) on bijna-dood ervaringen en bewustzijn. Felix Meritis, Amsterdam, 19 September 2006 - Wat is dementie? Discussion in 'Alzheimercafé', Van de Die-restaurant, Amsterdam, 26 September 2006. - What the bleep do we know? Onderdeel 'Interview' in het programma rondom het Brainspotting festival 8-10 October 2006. Masterclasses - Masterclass Neuroscience for PhD students. With Prof. J. Luo, Zhejian University School of Medicine, Shangzhou, P.R. China, 17 November 2006 - Masterclass Neuroscience. With Prof. J.N. Zhou, University of Science and Technology of China, Hefei, P.R. China, 21 November 2006 2007 Invited lectures - Ben jij slaaf van je hersenen? Discussieavond met VU en UVA studenten, together with Prof.dr. T. Dorelijers en Dhr. Van Oranje, Sociëteit L.a.n.x., Amsterdam, 2 February 2007 - Geslachtsverschillen in de hersenen. Themaconferentie voor vrouwen Gelijk maar toch anders, Politie Amsterdam-Amstelland, Amsterdam, Tuesday, 6 February 2007 142

- Biologische aspecten van geslachtsidentiteit en seksulele ontwikkeling. Studiebijeenkomst Seksualiteit en geslachtsverschil: eeuwige thema s in actuele gedaante, Vereniging voor Kinder- en Jeugdpsychiatrie, Utrecht, Tulip Inn Hotel, Garderen, Saturday 10 February 2007 - Human brain sex differences in relation to gender, sexual orientation and brain disorders. 4 th International Meeting, Steroids and Nervous System, Villa Gualino, Turin, Italy, 18-21 February 2007 - De vrije wil, een plezierige illusie. Symposium: De Verlichting: 150 jaar achteruitgang. De Rode Hoed, Amsterdam, 21 May 2007 - Debater on "Het puberbrein en de onbestuurbaarheid van jongeren" (the adolescent brain and the impossibility to steer the young"). Universiteitsdag, Oudemanhuispoort, Amsterdam, 9 June 2007 - Special lecture, The human hypothalamus in psychiatric and neurodegenerative disorders. Neuroscience Day, Department of Experimental Medical Science, Lund University, Lund, Sweden, 3 May 2007. - Neuro-theologie: hersenen en religie. Bijeenkomst Unitas Multiplex, Amstelveen, 1 May 2007 - Sexual differentiation of the human brain - gender identity and sexual orientation. PHI mini-symposium on Brain sexual dimorphism - Genes or hormones? Clayton, Victoria, Australia, 12 July 2007 - Sexual differentiation of the human brain. IBRO Congress, Melbourne, Australia, 14 July 2007. - Ontmoetingen. Vlaams-Nederlands Huis deburen, Brussels, Belgium, 10 December 2007 Public Lectures - De ontwikkeling van ons karakter. Genootschap de Nalatenschap van Hendrik VIII, Maastricht, 12 January 2007. - Toxische invloeden. Publiekslezing voor de Hersenstichting Nederland, Jaarbeurs Utrecht, 11 oktober 2007. - Seksuele differentiatie van onze hersenen en homoseksualiteit. Open contrario dag, Petrakerk, Harderwijk, 24 november 2007. Special Lectures - The human hypothalamus in health and disease. Symposium on Neuroendocrine Changes in Huntington s disease, Leiden, 16 March 2007 Miscellaneous - Opening lecture of exhibition of work by Kees Boer. Central Library, AMC, Amsterdam, 11 December 2007 2008 Invited lectures - De ontwikkeling van ons karakter. 3 e Congres Neurobiologie. Nieuw kompas voor de Forensische Psychiatrie? Pompestichting, Scandic Sanadome, Nijmegen 17 January 2008. - Seksuele differentiatie van het menselijk brein in relatie tot het geslacht en seksuele oriëntatie. Aangepaste thema-avond 'Scientific dogma en het probleem rond gender identity'. Emma Kinderziekenhuis, AMC Amsterdam, 15 April 2008. - Melatonin receptor localization in the human brain in health and disease. Pineal Cell Biology: Mechanisms of circadian rhythmicity and melatonin action. Il Ciocco Hotel and Resort, Lucca (Barga) Italy, 20-25 April 2008. - De ontwikkeling van ons karakter, focus op seks en agressie. Utrechtse AIO retraite, Lochem, 18 June 2008. - Activatie van neuronen bij de ziekte van Alzheimer. Alzheimercyclus AZVU, 5 June 2008. - Two lectures for the opening of the Academic Year on the invitation of Gezondheids- en Levenswetenschappen, Faculty of Aard- en Levenswetenschappen, Vrije Universiteit, Amsterdam. Title: Education and Environment have only a minor effect on us. Most of our characteristics are inborn. - Happiness and the Brain. Symposium Thoughts on Happiness. Oegstgeest, 5 November 2008. - Mechanismen van het placebo-effect; het zelfhelend vermogen van de hersenen. Congres Gezondheidszorg; meer dan techniek. 1 December 2008. - Geslachtsverschil in hersenontwikkeling en leerprestaties. Kapittelavond University of Utrecht, 12 November 2008. - Neurotheologie. Het Menselijke Brein. Erasmus Universiteit Rotterdam, 13 November 2008. - Neuro-theology: Demasqué of religions. For student society Congo in Amsterdam, 10 December 2008. - Hersenen en Psychiatrische Ziektebeelden. Stichting Ypsilon, 12 December 2008 Public lectures - Taboes in de wetenschap. Debate and interview. Volkskrant Kenniscafé. Meeting with the general public in De Balie, Amsterdam, 15 September 2008-2-hour lecture for Ons Karakter Als Aangeboren Afwijking. AUV-dag, Amsterdam, 8 November 2008. 143

Key lectures - Reactivatie van neuronen bij de ziekte van Alzheimer. Symposium Dr. G.J. Van Hoytema Stichting, University of Twente, Enschede, The Netherlands, 3 April 2008. - De neurobiologische ontwikkeling van genderidentiteit en seksuele oriëntatie. VKJP-congres "Seksualiteit bij Kinderen en Jeugdigen. De grens verkennen of overschrijden." Congrescentrum De Reehorst, Ede, 29 May 2008. Plenary lectures - Functioneel onderzoek in postmortem materiaal. Geriatriedagen, Beurs WTC Rotterdam, 14/15 February 2008. Lectures - Reactivation of neurons in Alzheimer's disease. Neuroscience & Vision Symposium, Netherlands Institute for Neuroscience, Amsterdam, 8 February 2008 - Introduction to the 18 th C.U. Ariëns Kappers lecture, 25 th International Summer School of Brain Research. Neurotherapy. Progress in Restorative Neuroscience & Neurology, 28 August 2008, Amsterdam Public debate - Voor ik het vergeet (Before I forget). Debate on elective death. De Rode Hoed theatre, Amsterdam, 11 November 2008 2009 Invited Lectures - Sexual differentiation of the brain in relation to gender identity and sexual orientation. Postgraduate lecture, Swedish Endocrinological Society, Malmö, Sweden, 29 January 2009 - Sexual differentiation of the human brain in relation to gender identity and sexual orientation. VII Conference Hormones, Brain and Behavior, Department of Anatomy, Pharmacology and Legal Medicine, Turin, Italy, 13 February 2009. - Hypothalamus, AVP and depressions. Postacademic teaching: Vasopressinerge mechanismen bij affectieve stoornissen. Boerhaave Commissie voor Postacademisch Onderwijs in de Geneeskunde. Leiden University Medical Center, 26 February 2009 - Een DNA bank ten behoeve van PTSD. Raad voor Civiel-Militaire Zorg en Onderzoek, De Zwaluwenberg, Hilversum, 11 March 2009. - Hersenen en Religie. Limmoed dag Amsterdams Lyceum, Amsterdam, 15 March 2009 - Neurotheologie. Rotary Minerva, Amsterdam, 11 May 2009 - Opening lecture: Sexual differentiation of the human brain in relation to gender identity and sexual orientation. University of Pavia, Italy, 23 April 2009. - Dementie en euthanasie. ALV of the NVVE, Jaarbeurs, Utrecht, 25 April 2009 - On age limits in the justice system. With Jacqueline Mulder. Dag van de wetgeving. Over de grenzen. Kurhaus, Scheveningen, 19 March 2009 - Workshop On age limits in the justice system. With Jacqueline Mulder. Dag van de wetgeving. Over de grenzen. Kurhaus, Scheveningen, 19 March 2009. - Speaker at the Minisymposium over doodswens chronisch psychiatrisch patiënten. ROC Nove College, 24 March 2009. - Sex hormones and the brain. Workshop Pediatric Neuroendocrinology: an update. Cagliari, Italy, 17-19 May 2009 - The Neurobiology of aggression: a prelude to violence? Lecture for the subject of Violence in Peace and War, UvA, 26 March 2009 - Mini lecture and debate titled "Opvoeden wat kun je?", Universiteitsdag 2009, UvA. - De evolutie van onze hersenen. Kennismakingslezing. Koninklijke Maatschappij voor natuurkunde, Diligentia, The Hague, 21 September 2009 - Plasticiteit van de hersenen en de ziekte van Alzheimer. Congres Neurorevalidatie, 18 November 2009, Jaarbeurs Utrecht. - The human hypothalamus. XVIII reunión Nacional de Morfología, Sociedad Mexicana de Anatomía A.C. Facultad de Medicina Y Cirugía, Universidad Autónoma 'Benito Juárez' de Oaxaca. Oaxaca de Juárez, Mexico, 6-9 October 2009. - Validation of animal-model circadian-system changes in aging for human brain disorders. XI Congress of the European Biological Rhythms Society in association with the Japanese Society for Chronobiology. 27 August 2009. - Plasticiteit van de hersenen en de ziekte van Alzheimer. Congres Neurorevalidatie, Jaarbeurs Utrecht, 22 September 2009. 144

- Dementiën en het levenseinde. Probus 84, Amstelveen, 25 November 2009 - De ontwikkeling van een neurobiologisch perspectief in de kinder- en jeugdpsychiatrie. AMC, Amsterdam, 26 November 2009. - Permanente invloed van chemische stoffen op de hersenontwikkeling van het kind. Regionaal Referaat 'Effects of Psychotropic Drugs on the Developing Brain". De Bascule, Amsterdam, 15 December 2009. Invited Discussion - 2 workshops on Leeftijdsgrenzen in het Recht. Workshop Dag van de Wetgeving, 19 March 2009. Keynote Lecture - Sexual differentiation of the human brain: relation to gender and sexual orientation. 20 th Anniversary C ongress of the ESPU, 6-9 May 2009, Amsterdam. Plenary Lecture - Sexual differentiation of the brain. Nederlandse Vereniging voor Psychiatrie, Martinitheater, Groningen, 3 April 2009. Public Debate - Opvoedingsdebat. Organized by Tumult and the Nederlands Jeugdinstituut. Tumultzaal, Utrecht, 27 October 2009 - Introduction to De ziekte van Alzheimer en euthanasie. Vrije Universiteit, 18 November 2009. - Forum member at the above public debate, 18 November 2009 Special Lecture by invitation on the occasion of the celebration of 10 years of the gender team) - Sexual differentiation of the human brain: relation to gender identity, sexual orientation, aggression and neuropsychiatric disorders, Dept. of Psychiatry, Karolinska Inst., Stockholm, Sweden, 4 November 2009 (Cecila Dheine) Seminar by invitation - Research in gender identity disorders. Karolinska Inst., Stockholm, Sweden, 5 November 2009 (Ivanka Savic) Symposium by invitation - Nature/Nurture: Wat is aangeboren en wat wordt bepaald door de omgeving. Scholierensymposium bij De Anatomische Les, AMC collegezaal 5, Amsterdam, 2 November 2009 - Het bedreigde brein in utero, foetale programmering. Symposium: De veilige baarmoeder?! De gevolgen van medicatie en schadelijke stoffen op de foetus. CineMec, Ede, 6 November 2009. - Depression, hormones and aging. Instituto Nacional de Psiquiatría Ramón de La Fuente Muñiz, Calzada México Xochimilco 101, Col. San Lorenzo Huipulco, 13 October 2009 - Neurodegenerative diseases: reactivation of neurons in Alzheimer's disease. Cinvestav-sede sur, Departamento de Farmacobiología, Calzada de los Tenorios 235, Col Granjas Coapa, 14 October 2009 - Neuro-theology: the brain and religion. Auditorio Luis Lara Tapia. Facultad de Psicología, Universidad Nacional Autónoma de México. 15 October 2009. Lectures as visiting professor - Neurobiology of depression. Tianjin Medical University General Hospital and visit Hospital, 7 September 2009 - Alzheimer's disease and reactivation of neurons. Tianjin Medical University, Basic Medicine Research Center and visit Center, 8 September 2009 - Eating disorders: focus on Prader-Willi syndrome. USTC, Hefei, 9 September 2009 - Dissection Human Brain (4 hours), Zejiang University School of Medicine, 14 September 2009 - Laboratorium techniques. Group of Prof. Ai-Min Bao, Zejiang University School of Medicine, 15 September 2009 - We are our brains. Zejiang Univ. School of Medicine (Prof. J.-H. Luo), 15 September 2009 - Master Class group of Prof. A.M. Bao, Zejiang Univ. School of Medicine, 16 September 2009. 2010 Invited lectures - The brain: two of a kind? Symposium "Brain for Anatomists" Nederlandse Anatomen Vereniging, 8 January 2010 - Ontwikkeling van ons karakter. Fellowsbijeenkomst, UvA, Amsterdam, 20 January 2010 - Neurotheologie. 21 January 2010. Fellows-optreden (Ontmoeting met toonaangevende hoogleraren van de UvA). Universiteit van Amsterdam, FEB Business School. - Neuro-anatomische aspecten van seksualiteit. Multiple Sclerose en neurodegeneratieve aandoeningen. Revalidatieseksuologie. Radboud auditorium, Radboud Universiteit Nijmegen, 22 January 2010 - Hormonen en Hersenen. Studium Generale, Groningen, 1 February 2010. - Dementie en het zelfgekozen levenseinde. Unitas, Amstelveen, 2 March 2010. 145

- Seksuele differentiatie van de hersenen van de mens. Congres 2010. Change of Mind. De ontrafelende psyche. Labyrint, Studievereniging Psychologie, Rivierduinen, Oegstgeest, 12 March 2010. - Gene expression in brain and premature Alzheimer disease, 7 th International Prader-Willi Syndrome Organisation, Taipei, Taiwan, May 20-21, 2010. - Progress in postmortem PWS research, 7 th International Prader-Willi Syndrome Organisation, Taipei, Taiwan, May 20-21, 2010. - Sexual differentiation of our brain: relation to gender identity, sexual orientation and neuropsychiatric disorders. Tianjing Medical University, Tianjing, P.R. China. May 17, 2010. - De neurobiologie van minder geaccepteerd seksueel gedrag. Perversie, Artis Symposium. Stichting Psychoanalyse en Psychiatrie, Artis Congrescentrum, Amsterdam, 18 June 2010. - Dementia. Introduction for the NVVE forum "Voor ik het vergeet" (Before I forget). Aula Haagse Hogeschool, Den Haag, 30 March 2010. - Aging and dementia in hypothalamic systems: functional consequences. The Tenth International Symposium on Neurobiology and Neuroendocrinology of Aging. Bregenz, Austria, 25-30 July 2010. - Gender identity and sexual differentiation of the human brain. European Society for Paediatric Endocrinology (ESPE), Prague, Czech Republic, September 22-25, 2010. - Seksuele differentiatie van de hersenen. Focus op seksuele oriëntatie. Faculty of Psychology, UvA, 15 September 2010. - Collaborating with Chinese scientists. Visit of the Chinese Academy delegation. NIN, Amsterdam, 13 September 2010. - Voorspelbaarheid en beïnvloedbaarheid van gedrag. Aftrapworkshop "Grondslagen HRM in 2020". Amsterdam, 13 September 2010 - Angst en depressie in het brein. Symposium Balans 2010. 1 October 2010, Beatrixtheater Utrecht. - Programmering van onze hersenen en recht. Minisymposium rechtbanken Haarlem en Amsterdam. Gerechtsgebouw Jansstraat 81, Haarlem, 7 oktober 2010. - Seksuele differentiatie van de hersenen en AIS, Erasmus MC Rotterdam, 9 October 2010 - Hoe werkt dat leren in onze hersenen? 100 jaar Montessori vrij & zelfstandig. Montessoricollege-Oost, Amsterdam, 13 October 2010. - Introduction and chairperson of the day at Symposium Genderdysforie, ABN AMRO Coolsingel Rotterdam, 20 October 2010 - De neurobiologie van kennis en intuïtie. Symposium Kennis en Intuïtie in de Geneeskunde. AMC, Amsterdam, 21 October 2010. - Wij zijn ons brain. Festival Key of Life. Theater of talks: Talks on the brain. De Waag, Mandenmakerssteeg, Leiden, 23 October 2010 - Gender identity, sexual orientation and brain structure structural and functional sex differences in the brain. 16 th International congress of the international society of psychosomatic obstetrics and gynecology. Scuola Grande S. Giovanni Evangelista, Venice, Italy, 28-30 October 2010. - Het bloed kruipt waar het niet gaan kan. Nascholing Hematologen, Rosarium, Amsterdam, 4 November 2010. - Het substraat, waar zit het geheugen? Symposium: Focus op geheugen, 11 November 2010, De Vrijhof, Universiteit Twente, Enschede. - Vroege programmering van schizofrenie, depressie en borderline in relatie met suicide, Horizon Tilburg, 27 November 2010. - Reactivation of neurons in Alzheimer s disease. University of Hamburg, 13 December 2010 Special lecture - Valedictory lecture. "Het doode lijf schenkt leering...": wat we over het leven leerden van dode hersenen. Afscheidscollege, AMC, 17 June 2010. Key lectures (invited) - Permanente effecten op de hersenontwikkeling van het kind in de baarmoeder. Gynaecongres, Breda, 3-4 June 2010 - Ouder, wijzer, beïnvloedbaarder. KNMG bijeenkomst, Groningen, 1 June 2010. Lectures as visiting professor - Visual art and the brain, China Academy of Art, Hangzhou, P.R. China, 12 April 2010 - Sexual differentiation of the human brain, Zhejiang University School of Medicine, Zhejiang, P.R. China, 13 April 2010 - Development of our character, Zhejiang University School of Medicine, Zhejiang, P.R. China, 13 April 2010 - Neurobiology of addiction, Zhejiang University School of Medicine, Zhejiang, P.R. China, 14 April 2010 - Neurobiology of eating disorders, Zhejiang University School of Medicine, Zhejiang, P.R. China, 14 April 146

2010 - Neurobiology of placebo effects, Zhejiang University School of Medicine, Zhejiang, P.R. China, 14 April 2010 - Sexual differentiation of the human brain: consequences for gender-identity, sexual orientation and neuropsychiatric disorders. Tianjin Medical University, Tianjin, P.R. China, May 2010 Public appearances - Interview at Book Fair Manuscripta on the occasion of the upcoming publication of Swaabs book Wij zijn ons Brein, van baarmoeder tot Alzheimer, Westerliefde, Amsterdam, 2 September 2010 Forum member - Voor ik het vergeet (Before I forget) Debate on dementia and elective death. Domus Medica, Utrecht, 4 October 2010. Discussion leader - Expertmeeting RZO (Civilian-Military Care Organization) on foreign mission-related disorders: the future and reconnaissance of a multidisciplinary approach. De Zwaluwenberg, Hilversum, 30 September 2010. Workshop leader - Uitburgeringscursus. Dementie en het zelfgewilde levenseinde, Jaarbeurs Utrecht, 22 November 2010. Debate - Op sterven na dood. De Rode Hoed, Amsterdam, 9 November 2010 - The free will delusion. Is geloven een vrije keuze? Zit geloven in brein, genen of het hart? Veritas forum Amsterdam, 29 november 2010. Debate and Introduction. 2011 Invited lectures - De evolutie van onze hersenen. Koninklijk Genootschap PHYSICA, Trefpuntskerk, Alkmaar, 10 January 2011. - Programmering van de hersenen en de (on)mogelijkheid van gedragsveranderingen. Spark Communicatie, Lido, Amsterdam, 20 January 2011. - Presentation, interview, discussion, with Bram Bakker, Literatuur in de Duinen, Bloemendaal, 28 January 2011. - Reactivatie van neuronen bij de ziekte van Alzheimer. Symposium Het Brein, Studievereniging Leonardo da Vinci, Centre for Cognitive Neuroimaging, Nijmegen, 28 January 2011. - Functionele teratologie; blijvende effecten van chemische stoffen op de hersenontwikkeling van het kind. AMC, Amsterdam, 31 January 2011. - We are our brain. IOT Onderzoekdagen, Lunteren, 3 February 2011. - Tijd in het brein. Studium Generale, Universiteit Utrecht, 16 February 2011 - We are our brain. Lecture for the William James Graduate School, Psychology Faculty, VU, 3 March 2011 - Escape from paradise, Lecture on the occasion of the Farewell Symposium for Kees Boer, AMC, 11 March 2011. - De werking van ons brein in conflictueuze situaties, Regiogroep NMI-mediators Haaglanden e.o., Hotel Den Haag-Wassenaar, te Wassenaar, 14 March 2011 - De neurobiologie van angst en agressie bij kinderen. Avondsymposium Balans, Haarlem, 11 April 2011. - Sexual differentiation of our brain. Mind the Brain Symposium, Utrecht, 12 April 2011. - Onze geest; van dode moleculen naar levende patiënten. Programma Geestkracht, ZonMw, Zwolle, 24 March 2011. - Wij zijn ons brein. 11th Nationaal Autisme Congres, Beurs WTC, Rotterdam, 18 March 2011 - Ontwikkeling van ons karakter. Hooglerarenreeks Breinkunde voor Managers. Focus Conferences, Nijenrode, 21 april 2011. - Wij zijn ons brein. Island Bookstore, Nassaukerk, Amsterdam, 26 April 2011 - Wij zijn ons brein. Graham CCC in collaboration with ING Wealth Management. No. 578, Amsterdam, 18 April 2011. - The impact of brain research on social debate and thinking in the Netherlands. Embassy of the Kingdom of the Netherlands, Beijing, China, 20 May 2011 - Wij zijn ons Brein. Lecture for the Universiteitsdag 2011, Aula of the UvA, 28 May 2011 - Hersenontwikkeling: van baarmoeder tot stemgerechtigd. Congres Van Pap tot Pizza, Nederlandse Academie van Voedingswetenschappen. NBC, Blokhoeve 1, Nieuwegein, 7 June 2011. - De evolutie van onze hersenen. Planetarium, Artis, 7 June 2011. - Function & dysfunction of the brain. Insane in the brain, AMC PhD symposium, 17 June 2011. - Muziektherapie en hersenziekten, Coolpolitics, Muziek telt! Pakhuis De Zwijger, Amsterdam, 22 June 147

2011. - Wij zijn ons brein. Zit-aan-Zee, VNA café meeting, 19 June 2011, IJmuiden. - Member of the forum on Neurowetenschappen in de forensische context. Forensisch symposium, Maastricht, 6 July 2011. - Wij zijn ons brein. Coolpolitics lecture, Lowlands University, Biddinghuizen, 19 August 2011. - Hersenen en Recht.!78ste plenaire SWR conferentie, Hotelconferentieoord ISVW, Leusden, 9 September 2011 - Forum member 25th Netherlands Brain Bank anniversary symposium, De Rode Hoed, Amsterdam, 15 September 2011. - Sexual differentiation of the human brain: consequences for gender-identity, sexua orientation and neuropsychiatric disorders. SiNapsa Neuroscience Conference 11, Ljubljana, Slovenia, 25 September 2011. - Dementie. Rosa Spier Huis, Laren, 27 September 2011 - Reactivatie van neuronen bij de ziekte van Alzheimer, Pearson Assessment and Information. Neuropsychologisch congres Het Lerende Brein. NEMO, Amsterdam, 29 September 2011. - Één jaar Wij zijn ons Brein. Openbare Bibliotheek Amsterdam, Theater van t Woord, Santpoort, 3 October 2011 - Wij zijn ons brein. Beverwijkse Boekhandel, Kennemer Theater, Beverwijk, 4 October 2011. - Vrije wil bestaat niet. General Counsel Retreat, Allen & Overy, Duin en Kruidberg, 5 October 2011 - Seksuele differentiatie van de hersenen. Polemiek in de Metaboliek, Continuum Endocrinologie, Kasteel de Vanenburg, Putten, 6 October 2011. - Hersenen en Muziek (together with Johannes Leertouwer). Tap cultuur, Grand Hotel Karel V, Utrecht, 11 October 2011. - Wij zijn ons brein. Bibliotheek Spijkenisse, 12 October 2011. - Hersenen en Recht. Gerechtshof Den Haag. 13 October 2011. - Zijn wij ons brein en geldt dat ook voor de aandoening schizofrenie? 3e dinsdagavondprogramma Ypsilon, Mentrumkliniek, 18 October 2011. - De neurobiologie van dakloosheid, verslaving en criminaliteit. CoRaad Symposium Seks, drugs en dakloos. De Amsterdamse patiënt. ABN-AMRO, Amsterdam, 21 October 2011. - De zetel van zonderlinge verschijningen. Skepsis congres Brein en Illusie. Hogeschool Domstad, Utrecht, 22 October 2011 - Participant in The Battle of Ideas. Institute of Ideas and Royal College of Art, London, UK, 30 October 2011. - Brain and Art. Lecture for the Museumnachtlezing, Special collections of the University of Amsterdam, Oude Turfmarkt 129, Amsterdam, 5 November 2011 - Geslachtsdifferentiatie van onze hersenen. Het Testosteronplafond. Towards women in science and technology, 9 November 2011, Museumcafé Renzo, Science Center NEMO, Amsterdam - Sexual differentiation of the human brain: relationship to physiology and disease. International Conference Sex and Brain, Nijmegen, 11 November 2011 - Wij zijn ons brein. Gebruik je hersens! 5 e lustrum Senioren Academie, RU Groningen, 1 December 2011 - Live interview on Carré stage. Volle Maan, A Kind of Magic, on living with HIV, 3 December 2011 - Wij zijn ons Brein. Senioren Academie. Gezelschap Senioren Vrije Universiteit. Medische Faculteit VU, 6 December 2011 - Wij zijn ons Brein. Bibliotheek Amstelland, 7 december 2011 - Gastcollege Docenten Blok Verkiezingen, VU, Amsterdam, 8 december 2011 - Informatie productiviteit Hersenen & Informatieverwerking, NIN, Amsterdam, 12 december 2011 - Deelnemer debat over Psychiatrische ziekten zijn hersenaandoeningen. Ter gelegenheid van de verschijning van het Handboek Psychiatrie en Filosofie (Damiaan Denys en Gerben Meynen), Rode Hoed, Amsterdam, 14 december 2011. Keynote lectures (invited) - De ontwikkeling van ons karakter en de aanleg voor psychiatrische ziekten: consequenties voor preventie en behandeling. Studium Generale, Maastricht University, 17 Februari 2011 - Re-activation of neurons in Alzheimer s disease. BIT s 2 nd Annual World Congress of NeuroTalk, Dalian, China, 23 May 2011. - Het bedreigde kinderbrein. Nationaal Congres 2011 Praktische Pediatrie, Apeldoorn, 15 December 2011. 2012 Invited lectures 148

- Lange-termijns effecten van anesthesie bij kinderen. Seminar, afdeling Anesthesie, AMC, Vermeulen Cranch zaal, 11 January 2012 - De noodzaak en risico s van activatie van onze hersenen in de verschillende levensfasen. Kerkrade, Brainparty Continuum, 14 January 2012. - Leren en Geheugen. Lezing voor Personeelsdag Alpha Scholengroep, De Zeeuwse Stromen, Renesse, 25 January 2012 - Depressie: een hersenontwikkelingsstoornis. Studium Generale, Maastricht University, 9 February 2012 - Prenatal influences on the development of behaviour. 3rd Year Symposium GZ Psychologie. Meeting Plaza, Utrecht, 14 February 2012. - Adolescence. Beta-Break. Discussie voor studenten van het SILS. Amsterdam, UvA, 16 February 2012 - Simpele opvattingen over complexe breinen. Paradisolezing, 29 January 2012 - Hersenen en recht, Ottone bijeenkomst, Utrecht, 24 January 2012 - Sexual differentiation of our brain, relations to gender identity and sexual orientation. Leidsche Ganymedes Borrel, Groot Auditorium, University of Leiden, 27 January 2012. - Stress systems in dementia. Joint PAIC and EU-COST action: Pain in impaired cognition, especially dementia. LUMC, Leiden, 13 January 2012 - The biological clock: life time involvement. Leiden Institute for Brain and Cognition (LIBC): Sylvius Lecture. 6 February 2012. - Lecture: Grijze cellen: Zijn wij ons brein? Handelsbeurs, Concertzaal, Gent, Belgium, 22 February 2012 - Wij zijn ons brein. Technische Universiteit Eindhoven, 25 February 2012 - Gender identity, sexual orientation and the brain. 15 th World Congress of Gynecological Endocrinology, Florence, Italy, 10 March 2012 - De Toegift. Metabole Dag 2012: Endocrinologie in de praktijk. Media Plaza, Jaarbeurs, Utrecht, 21 March 2012. - Wij zijn ons brein. Vroege programmering van onze hersenen. 8 ste Landelijke Studiedag Implantologie, NVOI, Hilton Ballroom, Amsterdam, 30 March 2012. - Pedofilie is geprogrammeerd in ons brein. Pedofilie Aandoening of geaardheid. Medilex, De Driehoek, Utrecht, 28 March 2012. - Scan Uzelve. Breinkunde voor Managers. Hooglerarenreeks, Universiteit Nijenrode, 31 March 2012 - Muziek, hersenontwikkeling en hersenziekten. Muziek en het Brein, Lustrum VSP-VU, Amstelzaal VU, 5 april 2012. - Het kwetsbare jonge brein. Congres Samen nog Beter. 12 april 2012, Woudschoten, Zeist. - Wij zijn ons brein. Functionele teratologie. Samen nog Beter. 12 april 2012, Woudschoten, Zeist. - De grenzen, dat is het brein. Grenzen, Cobra Dagen 2012, Leeuwenhorst Congrescentrum Noordwijkerhout, 20 april 2012. - Het bedreigde kinderbrein. Themadag Neurologische Ontwikkeling en Gedrag. Landelijke Onderwijsdag, 13 april 2012. - Het kwetsbare kinderbrein. Afscheidssymposium Rob Pereira, Maasstad Ziekenhuis, Rotterdam, 27 april 2012. - Het bedreigde kinderbrein. Stichting Fedra, Philharmonie, Haarlem, 21 mei 2012 - The impact of neuroscience findings on information productivity. EIM 2012, Leerhotel Het Klooster, Amersfoort, 23 mei 2012. - Introduction. Battle of the Brains, EduMind, 11 juni 2012 - Hersenen, geest, bewustzijn en vrije wil. Unitas Multiplex, Amsterdam, 12 juni 2012. - Wij zijn ons brein. AS Prometheus, Lipsius, zaal 003, Leiden, 20 juni 2012. - Jouw hersenen zijn fascinerend. ISBW opleidingen, Regardz Planetarium Amsterdam, 21 juni 2012 - De kracht van het verschil. Female Capital BAM congres 2012, Maasgebouw bij De Kuip, Rotterdam, 3 juli 2012 Debates (invited) - Identiteit, religie en het brein, wat bepaalt wie wij zijn. Jacobikerk, Utrecht, 18 January 2012. - Debate: Grijze cellen: Zijn wij ons brein? Handelsbeurs, Concertzaal, Gent, Belgium, 22 February 2012 - Debate: Does it take two to tango? De Ziel en/of Het Brein. Feest van de Filosofie. Hoger Instituut voor Wijsbegeerte, Leuven, België, 31 maart 2012. - Nacht van de Filosofie. Debat Wij zijn ons Brein met Bert Keizer en Marc Slors. 13 April 2012 - NRC Academie Vrije Wil. 3 debates. Landgoed ISVW, Leusden, on 1 May 2012. - Debating match and varying debates, Opvoeden (Swaab tegen de rest van Nederland) Zorgen aan Zee, Vlissingen, 1 June 2012. Masterclasses (invited) - Bewustzijn, schizofrenie, geheugen. Masterclass Honours programma BMW, Universiteit Utrecht, 30 149

January 2012. Keynote lectures (invited) - Visual Art and the Brain. Art Department, Zhejiang University, P.R. China, 16 March 2012 - Brain, Mind and Neuroscience, Hangzhou Buddhism Academy, P.R. China, 17 March 2012 - De positieve kanten van het ouder worden. Zin in Ouder Worden. Innovatieve visies ACA 2012, VU, 31 May 2012 - Introductie. Zorgen aan Zee. Vlissingen, 1 June 2012 - Neuroscience. 19 th International Student Congress of (bio)medical Sciences (ISCOMS), Groningen, 6 June 2012 Public lectures (invited) - Functional Brain Anatomy (Human Brain Dissection, Zhejiang University School of Medicine), 19 May 2012 Workshops (invited) - Workshop neuroscience, 19 th International Student Congress of (bio)medical Sciences (ISCOMS), Groningen 6 June 2012 150

Meetings with the press/media/swaab s research in the national and international (popular) press, recorded since 1997 1997 Heilzaam licht ( The benefits of light ) In: Plus, December 1997 Hersenen zonder hiërarchie ( no hierarchy in the brain ) In: NRC Handelsblad, 29 November 1997 Hormone gegen geistigen Verfall ( Hormones against the decaying brain ) In: Süddeutsche Zeitung, 9 January, 1997 Verlichting van het slaapprobleem ( A solution for disturbed sleep ) In: Het Parool, 18 January 1997 Licht verlicht het Alzheimer leed ( Light can lighten the burden of Alzheimer ) In: De Telegraaf, 5 July 1997 Nieuw licht op winterdepressie ( Light and winter depression ) In: VPN, 23 October 1997 Gesprekstherapie voor werkloze hersencellen ( Talking about inactive brain cells ) In: AMC Magazine, May 1997 Master debat ( Master debate ) In: Verband, September 1997 Meer licht voor grijs ( Light for Grey ) In: AMC Magazine, Januray 1997 Wegenwacht bij zenuwschade ( repairing nerve damage ) In: Scan, no. 4, 1997 1998 Sex on the brain In: The Observer Review, 8 November 1998 Laat mij maar werken ( I m better off working ) In: Algemeen Dagblad, 30 April 1998 In tachtig plakjes ( 80 slices ) In: Limburgs Dagblad, 15 August 1998 Dick Swaab in tachtig plakjes( Dick Swaab in 80 slices ) In: Tubantia, 27 June 1998 Amsterdam conference on Alzheimer s disease In: The News, June 1998 Alzheimer te lijf ( Fighting Alzheimer ) In: De Volkskrant, 18 July 1998 Alzheimer als hart- en vaatziekte ( Alzheimer and coronary disease ) In: Het Parool, 18 July 1998 Sluipmoord op de hersenen ( Assassination of the brain ) In: Haagsche Courant, 18 July 1998 Hersenziekte ( Brain Disease ) In: Vrij Nederland, 19 December 1998 Demente ouderen onder kunstzon ( Demented elderly treated with artificial sunlight ) In: Algemeen Dagblad, 22 June 1998 Doel van de geneeskunde raakt op achtergrond ( Losing sight of healing ) In: NRC Handelsblad, 20 June 1998 Depressie zit écht tussen de oren ( Depression is a disease of the brain ) In: De Telegraaf, 13 June 1998 Alzheimergolf nog niet te keren ( Alzheimer floodgates opened ) In: De Telegraaf, 20 June 1998 Niks Frankenstein, niks luguber ( Neither Frankenstein nor sinister ) In: De Gooi- en Eemlander, 27 June 1998 Zo complex als het heelal ( As complex as the universe ) In: Drentse & Asser Courant, 27 June 1998 Op naar de hersenbank ( Let s go to the brain bank ) In: Het Parool, 30 March 1998 Oren lesbiennes lijken op die van mannen ( Lesbians have male ears) In: Trouw, 11 March 1998 Sporen van leven na de dood ( Traces of life after death ) In: De Telegraaf, 28 February 1998 Dementia linked to faulty RNA In: New Scientist, 17 January 1998 De fout zit niet in de streepjescode, maar in de afleesapparatuur ( It s not the bar code that s faulty, it s the scanner ) In: Utrechts Univ. blad, 22 January 1998 Een depressie zit tussen de oren ( Depression is a brain disease ) In: Psychologie, January 1998 Ouder wordend DNA heeft leesbril nodig ( Aging DNA needs reading glasses ) In: Het Parool, 10 January 1998 Vertaalfout ( Translation error ) In: NRC Handelsblad, 10 January 1998 Boodschapper krijgt de schuld van dementie ( Don t blame the messenger ) In: De Volkskrant, 10 January 1998 151

Het hart klopt ook in het hoofd ( The heart also beats in the head ) In: AMC Magazine, March 1998 Een nieuwe kijk op het ontstaan van de ziekte van Alzheimer ( A new way of looking at Alzheimer s disease ) In: Mediator, February 1998 Vochtverlies door knipfouten ( Loss of fluids due to cutting errors ) In: AMC Magazine, April 1998 Cellen tellen in hersenkernen ( Counting cells in brain nuclei ) In: Neuropraxis, no. 2, 1998 Seksualiteit zit echt tussen de oren ( Sex on the brain ) In: AMC Magazine, May 1998 Neuronale veranderingen bij depressie ( Neuronal changes in depression ) In: Neuropraxis, no. 3, 1998 Het zit niet in de genen ( It s not in the genes ) In: Akademie Nieuws, February 1998 Sex im Kopf ( Sex on the brain ) In: Münchener Medizinische Wochenschrift, 30 May 1998 Halszaak voor de psychiater ( Hanging matter for the psychiatrist ) In: AMC Magazine, December 1998 Overeenkomsten depressie en ziekte van Alzheimer ( Similarities depression and Alzheimer s disease ) In: De Psychiater, Oktober 1998 Alzheimer is een stofwisselingsziekte ( Alzheimer is a metabolic disorder ) In: Alzheimer Magazine, 1998 Tussen twee ijzeren tangen ( Iron grip ) In: Haagsche Courant, 6 October 1998 1999 Nederlands Instituut voor Hersenonderzoek bestaat negentig jaar: Steeds weer nieuwe contacten, steeds weer nieuwe verbindingen (Ninety years of the Netherlands Institute for Brain Research: A steady stream of new contacts) In: Folia, 18 June 1999 Seks in het brain ( Sex on the brain ) In: Elsevier, 21 August 1999 Onderzoek naar ontstaan depressie ( Causes of depression ) In: De Telegraaf, 16 October 1999 Zo n onderzoek speelt dag en nacht door je hoofd ( I always carry my research project with me ) In: Intermediair, 23 September 1999 Transseksueel heeft andere hersencellen ( The transsexual brain is different ) In: Het Parool, 15 January 1999 Mutilation won t make a man a woman In: The Guardian, 5 August 1999 Ramaermedaille voor grensverleggend onderzoek naar ontstaan depressies ( Ramaermedal for expanding the horizons for research into the cause of depression ) In: De Psychiater, no. 5, 1999 Gezond oordeel ( Judged healthy ) In: NRC Handelsblad, 24 April 1999 Herseninstituut viert 90-jarig bestaan (90 th Birthday Netherlands Institute for Brain Research) In: Akademie Nieuws, April 1999 Ontregeling stress-as leidt tot depressie - ook bij Alzheimerpatiënten ( Disorganized stress-axis leads to depression - also in Alzheimer patients In: Alzheimer Magazine, no. 10, 1999 Gevangene van eigen genen ( A prisoner of your own genes ) In: Hersenwerk 2002, no. 32, 1999 Geest en genen (Mind and genes) In: HP/De Tijd, 18 June 1999 Dicteren genen ons gedrag? (Do our genes dictate our behaviour?) In: Bio Nieuws, 1999 Naar de psychiater of naar de Cariben (A visit to the psychiatrist or to the Caribbean) In: UIT/VN, no. 25A, 1999 Roze genen ( Pink genes ) In: Intermediair, 17 June 1999 Tegen arrogante wetenschap ( Against the arrogance of science ) In: NRC Handelsblad, 12 June 1999 Historie contra genen ( History versus genes ) In: De Volkskrant, 12 June 1999 Het menselijk brein ( The human brain ) In: AMC Magazine, June 1999 De hersenpan: grijze machine of tuin van Darwin? (The cranium: grey machine or Darwin s garden?) In: Folia, 11 June 1999 152

Grens tussen leven en dood steeds vager ( Fading borders between life and death ) In: Algemeen Dagblad, 10 May 1999 Baby beslist ( It s the baby s decision ) In: Elsevier, 1 May 1999 Manke boodschapper voor gebroken zenuwen ( Limping messenger for severed nerves ) In: AMC Magazine, May 1999 Versmade melk ( Scorned milk ) In: NRC Handelsblad, 9 October 1999 Multidisciplinair onderzoek: het voordeel van ellende ( Multidisciplinary research: the benefits of misery ) In: NBMF Nieuws, June 1999 De technische mens ( Technical man ) In: De Groene Amsterdammer, 15 December 1999 2000 Fundamenteel onderzoek naar achtergronden dementie (Fundamental research into background of dementia) In: Mediator, no. 7, 2000 Alzheimer kun je voorkomen met een interessante baan (prevent Alzheimer with an interesting job) In: HN, November 2000 Vaccin tegen Alzheimer ( Alzheimer vaccination ) In: Intermediair, 27 July 2000 Wij zijn onze hersenen ( Brains R Us ) In: Trouw, 30 September 2000 Een vorm van hersendood ( A kind of brain death ) In: Het Parool, 10 October 2000 Ontspoorde hersenen ( The brain derailed ) In: NRC Handelsblad, 30 December 2000 Hersenherstel na celtransplantatie ( Cellular transplants could repair the brain ) In: De Telegraaf, 16 December 2000 Een verlicht brein ( An enlightened brain ) In: Hersenwerk, no. 39, 2000 Zou het ooit nog wat worden met de psychologie? (Will psychology ever amount to anything?) In: Trouw, 14 October 2000 Klokkijken in de baarmoeder ( The clock and the fetus ) In: AMC Magazine, September 2000 Dementie beheerst discussie rond euthanasie ( Euthanasia debate hogged by dementia ) In: Relevant, no. 3, 2000 Revolutie in hersenonderzoek ( A revolution in brain research ) In: De Telegraaf, 1 January 2000 Nieuw initiatief voor hersenonderzoek ( New initiative in brain research) In: Ypsilon Nieuws, February 2000 Niets van wat ik noem is dé oorzaak van schizofrenie ( No one cause of schizophrenia ) In: Ypsilon Nieuws, February 2000 Alzheimer neemt epidemische vormen aan (Alzheimer epidemic) In: De Telegraaf, 15 April 2000 Wijs over grijs ( Grey Matter ) In: AMC Magazine, January 2000 Een opkikker voor het dovende brain ( A pick-me up for the fading brain ) In: De Volkskrant, 8 January 2000 Gebruik je hersens ( Use your brain ) In: Illuster, March 2000 2001 Anorexia is een hersenziekte, geen psychische kwaal ( Anorexia is a brain disease, not a psychiatric disorder ) In: Opzij, no. 10, October 2001 Baas in eigen brein ( Boss of your brain ) In: Relevant, no. 3, 2001 Laatste doorbraak van het jaar ( Last breakthrough of the year ) In: Het Parool, 29 December 2001 Breinreis naar het verleden ( Trip down memory lane ) In: AMC Magazine, April 2001 Als je temperatuur stijgt, begin je wakker te worden ( When your temperature rises, you re waking up ) In: Akademie Nieuws, December 2001 Masculien feminisme ( Masculine feminism ) In: De Volkskrant, 15 December 2001 Veroudering van de grijze massa ( Brain Aging ) In: AMC Magazine, January 2001 Verschil moet er wezen ( Distinctions are fine ) In: Folia, 9 March 2001 In het diepst van mijn gedachten ( My deepest thoughts ) In: KuZien, Winter 2000/2001 Een geleerde in kniebroek ( A scholar in plus fours ) In: Folia, 1 June 2001 Wat wil het brein? (What does the brain want?) In: NRC Handelsblad Magazine, June 2001 Het roze raadsel ( The pink riddle ) In: Elsevier, 16 June 2001 De Nederlandse Hersenbank speelt essentiële rol bij Alzheimer onderzoek 153

( Netherlands Brain Bank plays vital part in Alzheimer research ) In: Alzheimer Actueel, Spring 2001 Avondje tv beter dan sporten ( An evening of telly is healthier than exercise ) In: De Telegraaf 20 June 2001 No sports In: De Volkskrant, 7 July 2001 Hersens voor onderzoek ( Brains for research ) In: Elsevier, 13 January 2001 De temperatuur van een goede nachtrust ( The temperature of a good night s sleep ) In: AMC Magazine, December 2001 Zenuwen lokken ( Tempting nerves ) In: De Volkskrant, 16 February 2002 Criminele hersenen ( The criminal brain ) In: Natuur en Techniek, November 2001 2002 Hersenen zijn aaibaar geworden ( The cuddly brain ) In: Natuur en Techniek, no. 12, December 2002 De biologische klok ( The biological clock ) In: Medisch Contact, 9 August 2002 Voor gek verklaard ( Certifiable ) In: PS van de Week, 27 July 2002 Hiermee kun je zowat alle bestaande genen checken ( A device that will check almost all known genes ) In: Akademie Nieuws, April 2002 Menselijke hersenen razendsnel geëvolueerd ( Super fast evolution of the human brain ) In: Het Parool, 13 April 2002 Eiwitten maken de aap ( Proteins are the difference between man and ape ) In: De Volkskrant, 13 April 2002 Stress van de creche ( Creche stress ) In: NRC Handelsblad, 7 April 2002 Een klein beetje leven na de dood ( A little bit of life after death ) In: AMC Magazine, March 2002 Genomica en t grote geld ( Genomics and the big money ) In: Folia, 22 March 2002 Hersencellen blijven leven ( Brain cells stay alive ) In: Volkskrant, 12 January 2002 Het belang van hersenvocht ( The importance of liquor ) In: Mensen Medisch, February 2002 Rat met dwarslaesie herstelt gedeeltelijk door nieuwe therapie ( New therapy helps rats partially recover from paraplegia) In: De Telegraaf, 7 February 2002 Hersencellen blijven leven ( Brain cells stay alive ) In: De Gooi- en Eemlander, 8 January 2002 Biologische klok maakt niet depressief ( Biological clock does not cause depression ) In: De Volkskrant, 12 January 2002 Agilent stakes its claim In: Genetic Engineering News, February 2002. Geen gedachten zonder fosfor ( No phosphor, no thoughts ) In: AMC Magazine, December 2002 2003 De mens is van beton ( Concrete man ) In: NRC Handelsblad, 3 January 2003 De risico s van beroepsboksen en koppen ( Risks of professional boxing and heading ) In: De Volkskrant, 12 November 2003 Boksverbod? (Banning Boxing?) In: NRC Handelsblad, 15 November 2003 Zélf in de schijnwerper: licht (A life in the spotlights: light) In: Gezondheidsnieuws no. 11, November 2003 Well stress, geen strijd ( Stress, yes, struggle, no ) In: De Volkskrant, 13 September 2003 Wel of geen schizofreen ( Schizo or no schizo ) In: Algemeen Dagblad, 15 August 2003 Hersenonderzoek van belang voor onderwijs ( The importance of brain research for education ) In:Staatscourant, 25 July 2003 Demente bejaarden hebben licht nodig ( Demented elderly need light) In: Dagblad van het Noorden, 7 August 2003 De ziel is een misverstand ( The soul is a mistake ) In: De Limburger, 2003 Atheïsten (Atheists) In: NRC Handelsblad, 29 April 2003 De ware ongelovigen ( True Disbelievers ) In: Nederlands Dagblad, 11 July 2003 Sekseverschillen in het brein ( Sex differences in the brain ) In: Sciam, June 2003 Theologie wetenschappelijk? (Is theology a science?) In: NRC Handelsblad, 28/29 June 2003 Nieuw debat zelfdoding ( A new debate on suicide ) In: De Volkskrant, 19 June 2003 Hotelroereifabriek ( Prefab scrambled eggs ) In: NRC Handelsblad, 21/22 June 2003 154

Een dag bij het herseninstituut ( A day at the Brain Institute) In: MSZien, 17 June 2003 Een ongewone erfenis ( An unusual inheritance ) In: De Neuroloog, no. 2, 2003 Mannelijkheid zit in je brein ( Masculinity is in your brain ) In: Psychologie Magazine, 30 April 2003 Début de siècle. De opkomst van het ietsisme (The rise of something-ism ) In: Vrij Nederland, 19 April 2003 Zonder beschermengel red je het niet ( You need a guardian angel ) In: Mediator, no. 2, March 2003 Tussenmensen ( not a male, not a female ) In: Vrij Nederland, 15 March 2003 Hoe bevlogen kun je zijn? ( A passion for research ) In: MS Nieuwsbrief, no. 18, 2003 Breingeheimen ( Secrets of the brain ) In: Algemeen Dagblad, 12 March 2003 Training houdt de hersens fit ( Training keeps the brain fit ) In: De Volkskrant, 8 March 2003 Het jatten van kennis ( Stealing knowledge ) In: Elsevier, 22 February 2003 Lesbisch klonen onzin ( Lesbian cloning is nonsense ) In: De Telegraaf, 7 January 2003 Exploring the brain: a search for ourselves In: BCN Nieuwsbrief, January 2003 Het brein beslist pas later ( The brain makes up its mind later on ) In: AMC Magazine, January 2003 Transseksueel heeft vrouwelijke hersenen ( Transsexuals have female brain ) In: Het Parool, 6 January 2003 Bescherm je brein ( Save your brain ) In: Men s Health, December 2003 2004 Een zoektocht naar jezelf. In: Hersenmagazine, jaargang 2, nr. 2, June 2004. Interview met Prof.Dr. D.F. Swaab (Interview with Prof.dr. D.F. Swaab) In: Sarcoïdose Nieuws, jaargang 23, March 2004 Stimulatie van neuronen en functioneel herstel In: Alzheimer Nederland, pag. 3, 2004 ("Neuronal stimulation and functional recovery") IJveren voor Chinees Onderzoekstalent In: Status, nr. 16, jaargang 13. November. Interview with Dick Swaab 2005 Denken over hersens In: De Volkskrant, 29 January 2005. (Thinking about the brain) De eerste stap in de wetenschap van Dick Swaab (Dick Swaab s first steps in science). In: Akademie Nieuws 81, February 2005. Nee, de baarmoeder is niet veilig (The womb is not a safe place) In: NRC Handelsblad. 6 February 2005. Passie op de kubieke centimeter (Passionate about a cubic centimeter) In: AMC Magazine, nr. 2, February 2005. Het hersenonderzoek kent geen taboes meer (No taboos in brain research) Hersenen van doden zijn van levensbelang (The brains of the dead are vital) Geen mens die de pijn ziet (Invisible pain) 155 In: Bionieuws 4. Jaargang 15, 25 February 2005. In: MSzien no 1. 25 February 2005. Interview met Dick Swaab & Inge Huitinga In: De Volkskrant, 5 March 2005. Interview about pain in dementia (research done with Prof. dr. E.J.A. Scherder). Homo ruikt zoals vrouw (Gays noses smell what females smell) In: NRC Handelsblad, 10 May 2005 Verschil in hersenen homo s en hetero s (gay brain is different from straight brain) In: Metro, 11 May 2005 Homoseksuele hersenen (Homosexual brain) In: Quest, April 2005 Bedorven brein (Brain gone bad) In: Medisch Contact, 29 April 2005.

'Homokwabjes' (Location of homosexuality) In: 'Het testosteron-effect' in Psychologie Magazine, June 2005 Sex differences in the human brain Public debate organized by the European Dana Alliance for the Brain and Imperial College London, 5 July 2005 Hersenen en psychiatrie (Brains and psychiatry) 2, pp. 74-78. June 2005 In: Kind en adolescent praktijk, jaargang 4, nr. Een hoofd voor hersenen: neurobioloog Dick Swaab dissecteert In: Humo, augustus 2005 Een kwart eeuw Stichting MS Research, deel 2 In: MenSen, nr. 4, October 2005-10-03 (A quarter of a century for the MS Research Foundation) Ons karakter wordt in baarmoeder bepaald In: Spui, Res. Academicae, 2, p. 4-5, 2005 (Our character is determined in the womb) Tussen jongen en meisje In: NRC Handelsblad, 24 July 2005. (Between a boy and a girl) Pas als dat been eraf is, voel ik me compleet (I won't be whole until that leg comes off) In: Psychologie Magazine, July/August 2005 Amsterdammer van hart tot hersens (An Amsterdammer in heart and brain) In: Het Parool. 26 September 2005 Gebruik je hersens (Use your brain) In: Cheerz, no. 1, 2005. Anders maakt eender (Differences create sameness) In: NRC Handelsblad, 8/9 October 2005 De mythe van het agressie-gen (The aggression gene myth) In: Vrij Nederland, 15 October 2005 Oosterse naalden door Westerse ogen (Acupuncture as seen by the Western world) In: Status, AMC, October 2005 Newspaper report on the Lustrum Academische Club In: Folia, 21 October 2005 Een verjongingskuur voor het brein (Rejuvenation therapy for the brain) In: AMC Magazine, November 2005 Waarom opvoeden geen zin zou hebben (Is there any sense in trying to raise children well?) In: Ouders van nu, December 2005 Hersenen van doden zijn van levensbelang (The brains of the dead can help the living) In: Rondom MS, December 2005 2006 Denken over het brein (Thinking about the brain) In: Nieuw Israelitisch Weekblad, January 2006 Hersenonderzoeker zou het beter gedaan hebben dan 'intelligent ontwerper' (Brain researcher would have done a better job than the 'intelligent designer') In: Nederlands Dagblad, 21 January 2006 Hersenen van overleden mensen zijn van levensbelang (The brains of the deceased are of vital importance) In: RondOm MS, nr. 24, 2006 Zijn mannen nog te verbeteren? (Can men be improved?) In: Opzij, March 2006 Kwade homo's zaten aan de verkeerde kant In: Gay Krant 554, 2006 (Angry gays got it all wrong) Je kunt aan een karakter weinig veranderen (Character can't really be changed) In: Living, autumn 2006 De keuze van Dick Swaab (Dick Swaab's choice) In: De Academische Boekengids 58, Sept. 2006 De maat genomen. Topmannen langs de feministische meetlat In: Topmannen langs de feministische meetlat. Uitgeverij Archipel, 2006. 2007 Mist in het brein (Fog in the brain) In: Psychologie Magazine, February 2007 Schaken en Alzheimer 156

(Chess and Alzheimer) In: Zsana, February 2007 Alzheimer: nog steeds geen remedie (Alzheimer: still no remedy available) In: Zsana, March 2007 Bij demente bejaarden. Kwaliteit van leven groter met fel licht In: De Volkskrant, 28 June 2007 (Bright light brings better quality of life for demented elderly). Minder van slag met TL-buizen en een pil In: AMC Magazine, no. 6, June 2007 (Tube lighting and a pil mean less confusion) Meer licht helpt tegen dementie In: De Telegraaf, 22 June 2007 (More light to improve dementia) Hersenen maken de man/vrouw In: Aware Psychologie, nr. 3, 2007 (The brain makes the man/woman) Het brein is lang niet zo flexibel als we hopen (The brain is no way near as flexible as we would like) In: Psychologie Magazine, December 2007 Van alle markten thuis. In Quest. December 2007 (Jack-of-all-trades) 2008 Hebben homo's gevoeliger hersenen? (Are gay men's brains more sensitive?) In: Psychologie Magazine, May 2008. Licht helpt demente bejaarde (Light is beneficial to demented elderly people) In: De Volkskrant, 11 June 2008 Slecht slapen door falende hersenen (Failing brain causes bad sleep) In: AMC Magazine, June 2008 Gezocht: hersenen. (Wanted: brains) In: De Telegraaf, 17 June 2008 De mens is niet langer maakbaar (Man is not makeable any more) In: Ad Valvas, 4 September 2008 Permanent sabbatical in eigen lab. (Permanent sabbatical in own lab) 2008 M/V: wat maakt een brein mannelijk of vrouwelijk? (M/F: what makes a brain male or female?) 157 In: Reformatorisch dagblad, 28 November In: Quest Gezond. Special issue on the brain, autumn 2008 Dick Swaab en het homokwabje (Dick Swaab and the gay lobe) In: Akademie Nieuws, December 2008. 2009 Aangeboren slecht In: NRC Handelsblad, 24/25 January 2009 (Born bad) Van drinken krijg je geen bolleboos In: NRC Next, 6 February 2009 (Alcohol does not a bright child make) Geniepige karakters In: Quest, Special over Psychologie, nr. 15, 2009. (Sneaky characters) Wie we zijn wordt grotendeels bepaald in de baarmoeder In: Psychologie Magazine, themanummer, April 2009. (Our character is mainly determined in the womb) Het individuele karakter is reeds in de baarmoeder vastgelegd In: De Psychiater. Jaarg 16, no. 1, Jan 2009. (The individual character is determined in the womb) De overheid moet meer betrokken worden bij hersenonderzoek (The government should be more involved in brain research) 2, June 2009. Kneedbare hersenen. In: Elsevier, 27 June 2009. (Pliable brains) Dementie kan heel snel gaan In: Relevant, nr. 2, 2009 (Dementia can progress really quickly) NIN met slag en stoot naar honderdjarig jubileum In: Status, no. 9, June 2009. (NIN reaches 100 years - but not without a struggle) Een eeuw lang kronkels kijken In: Akademie Nieuws juni 2009 In: Hersenmagazine, Jaargang 7, no,

(a century of brain research) Als we alles bewust moesten doen, zouden we geen leven hebben In: KRO Magazine, no. 48, 2009 (If we had to think about everything we do, we wouldn't have time to live) Abnormaliteitsfobie In: NRC, 2009 (Abnormality Fobia) Verwaterde relaties (Diluted relationships) In: C2W Life Sciences, jaargang 105, #19, October 2009 Gek op kinderen en gestoord (Crazy about kids, and plain crazy) In: De Volkskrant, 19 December 2009 2010 Weg met de diëten. (Down with dieting) In: NRC Weekly. 2 January 2010 Swaab van het homokwabje gaat stug door (Swaab is undeterred) In: Het Parool, 18 June 2010 Swaab bepaalt zelf wanneer hij stopt (Swaab determines when it's been enough) In: Status, June 2010, no. 8, vol. 19 Alles, ook ons karakter, ligt vast in ons brein (Everything, including our character, is fixed in our brain) In: Dagblad van het Noorden, 26-06-2010 Bedankt, mam. (Thanks, mom) In: Quest Psychologie, no. 2, 2010, pp.14-17 Identity Crisis: What determines gender? In: Endocrine News, June 2010, pp. 30-33. Intuïtieve en zorgzame multitaskers (Intuitive and caring multitaskers) In: J/M voor Ouders, 14 th issue, no. 7/8, July/August 2010 Uitburgeren met Dick Swaab (Dick Swaab on subjects surrounding death) In: Uitvaart, 26 th issue, no. 9, September 2010 Overigens. Meningen van diverse publieke personen In: Folia, 64th issue, no. 02, 10-09-2010 (By the way) Neurobioloog Dick Swaab (65) neemt geen afscheid: "Er is nog veel te ontdekken" (Dick Swaab turns 65 but reckons retirement is not for him as there is still too much to discover) In: MSzien 2010, 3 Hersenonderzoeker bij toeval. (The accidental scientist) In: NRC Handelsblad, 12-06-2010 Een brein went nooit helemaal (Brain obductions never become a matter of routine) In: De Volkskrant, 12-06-2010 Met hersenen in de hand komt de dood heel dichtbij. In: Folia, vol. 63, no. 35, June 2010 (Holding a brain is a confrontation with death) Het brein is de baas (The Brain Rules) In: Medisch Contact, 65 th issue, 7 October 2010. Karakter ontstaat door chemie in baarmoeder. (Chemical reactions in the womb are the heart of our person) by Dick Swaab. De mythe van de eigen verantwoordelijkheid. Op: Joop.nl, 1 October 2010 De Vrije Wil is een plezierige illusie (Free will is a pleasant illusion) 158 In: Volkskrant, 2 October 2010, Letter In: De Groene Amsterdammer, 11 November 2010. Pensioen (Retirement) In: Spui, Uva Alumni Magazine, 02/2010, 33. 2011 Pedofiel, dat ben je gewoon (Pedophile? It can t be helped) In: Sp!ts, 10 January 2011 Straffen moet je eerst uittesten. (Efficacy of punishment should be tested before it s imposed) In: HP/De Tijd, 4 February 2011, pp. 16-18

Wij zijn ons brein (We are our brain) 159 In: Spiegeloog, nr. 338, issue 38, February 2011, pp. 13-15. Het brein is in, al is dat wel eens anders geweest (The brain is hot, but that wasn t always so) In: Metro, 25 January 2011 Werk is mijn grootste begeerte (My work is what I covet most) In: Trouw, 12 March 2011 Het begint in de baarmoeder (It starts in the womb) In: De Volkskrant, 12 March 2011 De stijl van Darwin is overweldigend (Darwin has an overwhelming style) In: NRC Handelsblad. Boeken, 10 March 2011 Mijn leven bestaat uit onderzoek en andere activiteiten die je niet meer kan doen als het brein het laat afweten. En dan heeft het leven ook geen zin meer. Interview in: Uit Vrije Wil. Waardig sterven op hoge leeftijd. Redactie J. Peters, E. Sutorius en anderen. Uitgeverij Boom, Amsterdam, pp. 85-88 We zullen nog lang mogen wachten op de wonderpillen (Miracle cure is still a long way off) In: Knack. 23 February 2011 Een bijna-doodervaring is kortsluiting van de hersenen (A near-death experience is a short-circuit of the brain) In: AD, 25 February 2011 Swaab weet overal iets van denken media (Swaab knows something about everything is what the media think) In: Status, April 2011, no.5, issue 20 Dick Swaab niet zo bang aangelegd (Dick Swaab does not scare easily ) In: Noordhollands Dagblad, 26 March 2011 In: Haarlems Dagblad, 26 March 2011 Dick Swaab: We zullen nog lang mogen wachten op de wonderpillen (We ll be waiting a long time for those miracle cures) In: Knack, 23 February 2011, no. 8, issue 41. Interview Dick Swaab In: Factaal, March 2011, no. 1, issue 11 Vrijwel alles ligt min of meer vast (Not much chance of change) In: Libelle, no. 17, 2011 Houdt doorwerken Alzheimer op afstand? In: Drukker dan Ooit. Werken na je 65 ste. Cisca Dresselhuys, Just Publishers. Dick Swaab antwoordt zijn critici In: NRC Weekend, 23/24 april 2011 (Dick Swaab s response to his critics) Jongens deden het ooit beter (Once upon a time boys did better at school) In: NRC Handelsblad 5 July 2011 Steun aan pedo s vermindert recidive In: De Volkskrant, 17 July 2011 (Buddies for pedophiles reduce the chance of repeat offenders) Eén keer leven is genoeg (One life is enough) In: De Telegraaf, 23 July 2011 Het gevaar van de geïsoleerde pedoseksueel (Isolating pedophiles does not help) In: NRC Weekend, 23/24 July 2011 Dick Swaab Zelfportret (Dick Swaab Self Portrait) In: HP de Tijd. week 30, July 2011 Het bestaan is één groot toeval (Being is Happenstance) In: VPRO gids, week 31, July 2011 Hersenen zijn hot. (The brain is a hot item) In: Sp!ts, 26 August 2011 Het is van alle tijden (Something that is and always will be there) In: De Volkskrant, 3 September 2011 Ik stop reacties in het laatje gek. (Some responses I have to file under mad ) In: NRC Next, 9 September 2011 Ook Swaab is zijn brein (Swaab, too, is his brain) In: NIW, nr.48, 16 September 2011 Minder placebo-werking bij dwangmedicatie? (Placebo-effect reduced in forced medication?) In: Psy, issue 15, no. 10, November 2011 (article by Dick Swaab and Gerben Meynen) Herseninstituut had een vacature (There was a position vacant at the Brain Research Institute) In: Trouw, 8 October 2011 De vrije wil is een illusie

(Free will is an illusion) In: De Morgen Magazine, 12 November 2011 Dick Swaab slaat terug naar zijn critici (Dick Swaab retaliates) In: Het Parool, 10 December 2011 Swaab riposteert (Swaab retaliates) In: AMC Magazine no 10, December 2011 Mijn kennis is beperkt (My knowledge is limited) In: ParaVisie, issue 26, December 2011 Mijn drive is een aangeboren afwijking. In: Libelle, nr. 52, December 2011. (My drive is inherited) Ons meest cruciale organ (Our most crucial organ) 160 In: Telegraaf. Bijlage De Uitdaging, December 2011 2012 Catherine interviewt Dick Swaab In: Gezond Nu. Januari 2012 (Catherine interviews Dick Swaab) De grens tussen normaal en psychotisch is grillig en vaag (The boundaries between what is normal and what is psychotic are fickle and vague) In: Alibi. Issue 42, no. 2, 2012 Boze homo s (Angry gays) In: Mare, 26 January 2012 Door internet een ander mens (A different person as a result of the internet) In: Nederlands Dagblad, 28 January 2012 Prikkel je brein via je zintuigen (Let your senses stimulate your brain) In: Sp!ts. Foreword in Special edition supplement, 29 March 2012 Guest editorial: About Neuroscience with Professor Dick F. Swaab In: Activitas Nervosa Superior Rediviva, volume 53, no. 4, 2011. De vraag is: heb je biologische aanleg of niet? (The question is, do you have the biological aptitude or not?) In: Over de Top. Haal het allerbeste uit jongeren. pp. 58-60. Kosmos Uitgevers, Utrecht, 2012 Als onze hersenen niet meer door onze zintuigen gestimuleerd worden gaan ze zelf informatie maken. (Brains that lack stimulation by the senses proceed to create their own information) In: Prikkel je brein via je zintuigen, 29 maart 2012. Het laatste oordeel. Dick Swaab, Neurobioloog (The Last Judgment. Dick Swaab, Neurobiologist) In: De Standaard, vrijdag 30 maart 2012 Pedo: kind onder kinderen In: Tubantia, 3 maart 2012 (Pedophile: child among children) De ziel is niet meer dan een misverstand (The existence of a soul is a misunderstanding) In: Campuskrant, tijdschrift van de KU Leuven, 28 maart 2012 Het onmuzikale brein van Dick Swaab (The non-musical brain of Dick Swaab) In: Ad Valvas, 19 april 2012 De ziel bestaat niet (The soul does not exist) In: Filosofie Magazine. Nr.4, jaargang 20, april 2012. De mens is een (on)bezield wezen (Humans do (not) have a soul) In: De Volkskrant, 7 april 2012. Zelfs van Mozart blijft niks over (Nothing remains, not even of the person Mozart) In: NRC Handelsblad, 18 april 2012. Doodsbang voor het slotakkoord (Scared to death of dying) In: Het Uitvaartwezen, mei 2012, p.9 Broers en Zussen (Brothers and Sisters) In: De Volkskrant, 16 mei 2012 Gesprek met Dick Swaab (Interview with Dick Swaab) Website Studium Generale Universiteit

Utrecht. Interview by Ed Veldhuizen Breinbodem in zicht. (Interview with Dick Swaab and Inge Huitinga) In: De Telegraaf, 15 juni 2012 Problemen bij de geboorte zijn het eerste syndroom (The first symptoms are problems with the birth) In: Vakblad voor Contextuele Hulpverlening, jaargang 17, nr 2, juni 2012 De computer in je hoofd (The computer in your head) In: Discovery Magazine, September 2012 De mens een dier? (Is man an animal?) In: Maarten, juli/augustus 2012 161

Swaab's/NIN research in national and international television/radio programmes/theatre January 8, 1998. BBC World news. Interview with Fred van Leeuwen November 24, 1998 Press Conference at the University of Pamplona, Navarra, Spain. TV Espagna. Interview with Fred van Leeuwen. January 10, 1998 Tros Nieuwsshow. Interview with Fred van Leeuwen January 10, 1998 Wereldomroep, European Edition. Interview with Fred van Leeuwen January 12, 1998 Wereldomroep, Latin American and World Edition. Interview with Fred van Leeuwen December 1998 Hardlopen is ongezond ('Running is bad for you') Interview with Dick Swaab for the Programme 'Wetenshoppen' (Broadcasting Company: Teleac/NOT) January 2000 Over de toekomst van de medische wetenschap ("The future of medical science') Interview with Dick Swaab for the programme Heerlijke Nieuwe Wereld (Broadcasting Company: AT5). December 2000 Gender Identity. Interview with Dick Swaab for the programme Horizon (Broadcasting company: BBC) October 2, 2002 Sleep-wake rhythms. Interview with Eus van Someren for BBC4 November 2, 2002 Sleep. Interview with Roy Raymann for Radio Rijnmond May 2003 Transsexuality. Interview with Dick Swaab for the programme Sex Change (Broadcasting company, TLC; Discovery). July 2003 Transsexuality. Interview with Dick Swaab for the programme Twee Vandaag (Broadcasting company: NOS) May 23, 2004 Radio interview met Dick Swaab in De Andere Wereld van Zondagavond. 'De grote vraag'. (Broadcasting company: EO). 2005 February 1, 2005 February 24, 2005 March 13, 2005 May 19, 2005 June 25, 2005 December 25, 2005 2006 September 21, 2006 Live radio interview with Theodor Holman in Desmet Live. Live radio interview for popular science radio show Hoe? Zo! (Teleac) with Prof. dr. H. Heymans Radiodocumentary about Dick Swaab, Humanistische Omroep. Live TV interview with Dick Swaab by Muntz & Van de Wint for the program "God bestaat niet" (God doesn't exist) in Parool Theatre, Amsterdam Live television interview with Dick Swaab by Frenk van der Linden for RTVNH Radio Rijnmond interview with Dick Swaab by Paul Verspeek. Commentator for tragicomic 'Alzheimer opera' in two acts. 2007 January 14, 2007 Tegenpolen. Live television interview Jacobine Geel with Dick Swaab and Rabbijn R. Evers over God (Broadcasting company: Ned 1). September 10, 2007 Hoe?Zo? Live radio programme due to the publication of "Born on a blue day" by Daniel Tammet. September 18, 2007 Alzheimer's disease. In Galileo (tv programme). September 22, 2007 Daniel Tammet. In Met het Oog op Morgen (radio show) September 23, 2007 Interview with Rob van Hattum (VPRO Television) with Daniel Tammet on autism/asperger (on the publication of "Born on a blue day" by Daniel Tammet) September 24, 2007 Pauw & Witteman. TV show. With Daniel Tammet. October 16, 2007 TV show in South Korea on transsexuality DVD published on the 60 th anniversary of the NVE ((Dutch Endocrine Society) Ha die Hormonen. Een boeiende endocrinologische les (CD-rom). 2008 February 20, 2008 March 26, 2008 April 18, 2008 May 23, 2008 Feromonen in haargel. RTL 4, Editie NL Bijnadoodervaring: waanzin of wetenschap? Profiel. TV programme about near death experiences. Op het randje. Interview in Folia nr. 29 van "Eindeloos bewustzijn" van Pim van Lommel Akademiepenning 2008. Radio interview Hoe?Zo!Radio. 162

November 6, 2008 Introduction film Max Baer's Last Right Hook (twice). Joods Filmfestival 2008, Amsterdam 2009 January 3, 2009 January 23, 2009 February 2, 2009 February 26, 2009 April 11, 2009 November 17, 2009 November 15, 2009 November 20, 2009 November 27, 2009 Interview within the framework of the Darwin year. Hoe?Zo!, Radio I, 6-8 pm. "Geschiedenis Live!"- Debat with Dutch Minister of Youth and Families. Arminiuskerk, Rotterdam. Swaab in AVRO radio programme De Praktijk. Series on Neuroscience. Other sessions with scientists from the NIN (P. Roelfsema, K. Bossers, I. Huitinga, J. Verhaagen, E. van Someren). Swaab in VPRO Television programme "Andere Tijden" Radio Interview: Napels bij Nacht. Hoe?Zo! Radio (Teleac). "Puberhormonen" & de Kettingvraag. Radio Interview in radio show "Andersdenkenden". TV program De Onrendabelen. VARA Broadcasting Company. TV program Eigen Schuld Dikke Bult, VARA Broadcasting Company. 2010 June 23, 2010 BBC interview "Goal of Vrije Wil". Legalization of assisted suicide for those elderly who consider their lives completed. June 14, 2010 Radio 1 interview on Goedemorgen Nederland, interviewer: Sven Kokkelman. June 16, 2010 Radioshow 'Met het oog op morgen', interviewer Henk van Hoorn. June 22, 2010 Radioshow 'Terugkijkend op mijn onderzoek'. Wereldomroep. May 14, 2010 Radioshow De Praktijk, radio 1, AVRO broadcasting. Spring 2010 Appearance in the DVD of the Netherlands Brain Bank October 2, 2010 Radio interview Wij zijn ons Brein voor TROS Nieuwsshow. October 7, 2010 Guest in television talkshow Pauw en Witteman. October 8, 2010 ARTE tv programme on Intersexuality. October 16, 2010 TV show in South Korea on transsexuality DVD published on the 60 th anniversary of the NVE (Dutch Endocrine Society) Ha die Hormonen. Een boeiende endocrinologische les (CD-rom). October 18, 2010 OBAlive, HUMAN Radio, interview by Theodor Holman about Swaab s long years of being a brain researcher November 9, 2010 Radio interview about elective death initiative and dementia, MAX broadcasting company, Radio 1, 8 pm. Radioshow: Twee dingen. November 6, 2010 Radio interview RTV-NH. October 25, 2010 BNR Gezond, radio interview 2011 January 1, 2011 Lekker dik? (A Fat Lot of Good?) TV programme on obesity, VPRO broadcasting company January 2, 2011 Het brein van Swaab (Swaab s brain), radio programme Labyrint, VPRO broadcasting company January 5, 2011 Chain question on transsexuality, Radio programme Hoe?Zo!, VPRO broadcasting company. January 11, 2011 RTL 4 News, radio interview on pedophilia. January 13, 2011 Radio interview on pedophilia for VARA broadcasting company, Radio 1. January 16, 2011 Live telephone interview for Turkish Television Programme on Revival of Brain Nerves. January 18, 2011 Live Interview for Radio Nederland Wereldomroep on fake pornography for pedophiles. January 20, 2011 Documentary by Jan-Willem Breure on pedophilia, to be broadcast on tv and internet. January 28, 2011 TV interview, VARA Uitgesproken. February 16, 2011 Profiel, Human Broadcasting Corporation. June 13, 2011 Radio interview on Uit Vrije Wil (a movement on voluntary life end) at Goedemorgen Nederland for KRO broadcasting company July 31, 2011 Zomergasten, all-evening televised interview. VPRO broadcasting company. August 4, 2011 Flikker op! KRO/VARA theme-night on homosexuality. 163

August 15, 2011 August 22, 2011 September 19, 2011 September 27, 2011 October 2011 November 2011 December 2011 2012 January 12, 2012 February 8, 2012 February 22, 2012 March 1, 2012 March 2, 2012 March 2, 2012 April 8, 2012 May 19, 2012 May 30, 2012 June 14, 2012 June 24, 2012 July 2, 2012 Coolpolitics/Lowlands University radio interview Doodgaan voor dummies. HUMAN broadcasting company Homoseksualiteit. Radio show Lust, BNN broadcasting company guest in TV programme Tijd voor Max, Omroep Max broadcasting company. Audio interview: www.geloofenwetenschap.nl/index.php/videoaudio.html Pavlov, NTR public broadcasting company. Interview in Danish magazine Weekendavisen Radiointerview voor L1 Radio. Jong. EO Broadcasting company. Radiointerview voor Radio 1 Joos. Vlaamse Radio- en Televisieomroeporganisatie De Kist, EO Broadcasting company Interview for French tv (Channel France 5) on the subject of euthanasia Videoclip to generate sponsoring for psychiatric research, with Jim van Os, University of Maastricht Radio interview for Labyrint, on the Religion Lobe. VPRO broadcasting company TV interview with Brandpunt, KRO broadcasting company TV interview for the programme Jong of the EO broadcasting company TV interview with RTL broadcasting company on filibustering in Dutch government Radio interview over deugen. IKON radio. TV programme Levy en de laatste Nazi s. AVRO broadcasting company Dick Swaab's name and/or research referred to in the written media/internet/other media "De oorlog, hij duurt maar voort", Volkskrant 20 December 2004 "Vrij Nederland, Piet Grijs en Buikhuisen" Vrij Nederland, 15 October 2005 "Lustrum Academische Club" in Folia, 21 October 2005 "Karaktervast" in NRC Handelsblad, 20 November 2005 "De hypothalamus en boulimia nervosa" AMC Magazine, 4 April 2005 "Moeder rookt? Meer kans op lesbisch kind", De Telegraaf, 9 September 2005 "Gif in baarmoeder hele leven schadelijk", De Telegraaf, 9 September 2005 "Lesbisch", De Volkskrant, 10 September 2005 "Ouders willen liever een heterokind", De Telegraaf, 10 September 2005 "Eindelijk goed nieuws voor moeders die denken dat ze voortijdig seniel worden", Libelle, September 2005 "Vrije wil", Parool, 15 October 2005 "Beltegoed in ruil voor afstaan DNA", Algemeen Dagblad, September 2005 "Geen kritiek s.v.p." Opzij, January 2006 "Tielman: gemiste kans". Gay Krant, 2006 "De onttakeling van Jaap de Groot". Het Parool, Uitmarktissue, August 2006 Chemie van de ziel, Prof. dr. B. Smalhout, De Telegraaf 20 January 2007 "Nieuw licht op de oorzaak van slaapstoornissen bij de ziekte van Parkinson." Arts en Apotheker 13 June 2007 "Nieuw licht op de oorzaak van slaapstoornissen bij de ziekte van Parkinson." Gezondheid.nl, 13 June 2007 "Vier antwoorden over het brein, voor al uw feestjes." De Volkskrant, 2 June 2007 "Bij demente bejaarden kwaliteit van leven groter met fel licht". NRC Handelsblad, June 28, 2007 "De uitdaging van het brein." Algemeen Dagblad, 29 June 2007 "Ėén nietig Y-chromosoom." De Volkskrant, 25 June 2007 So that others may live The Gathered View, May-June 2007 issue "Dementie, de epidemie van de toekomst?" Trouw, 18 September 2007 "Ik honger, dus ik besta". NRC Handelsblad, 23 September 2007 "Amsterdams Dagboek" (Daniel Tammet), De Volkskrant, 29 September 2007 "Onethische experimenten". Quest - braintainment, October 2007. Diverse recencies van "Over de Kop", met bijdrage van Dick Swaab "Reactiveren van neuronen in hersenweefsel van overledenen". In Alzheimer Actueel, zomer 2007 "Amsterdams Dagboek". In De Volkskrant, 29 September 2007 "Dat God liefde is, strijdt niet met evolutietheorie". In Trouw, 4 October 2007 164

"Plasterk wil scheiding geloof en wetenschap". Reformatorisch Dagblad, 4 October 2007 "De vriendelijke autist". In: NRC Handelsblad, 14 October 2007 "De vriendelijke autist 2". (ingezonden brief) In: De Volkskrant, 27 October 2007 "Schipperend voor ouder spelen". In: De Volkskrant, 30 November 2007 "De chemie van het vergeten". In C2W Life Sciences, 10 November 2007 "Kopzorgen". In Natuur, Wetenschap en Techniek. November 2007 "Voor God en de naaste home zijn met hoofd, hart en ziel", Nederlands Dagblad, 26 November 2007 "Deep brain stimulation". In The Gathered View, November-December 2007 "Homo-gevoelens zijn niet van graniet" In: Nederlands Dagblad, 1 December 2007 "De vriendelijke autist". In NRC handelsblad, 28 October 2007 "Corpus". Het Parool. 15 March 2008. "De bijna-doodervaring". Algemeen Dagblad, 26 March 2008 "Bijnadoodervaring: waanzin of wetenschap?" Spits, 26 March 2008. "Dick Swaab heeft een fantasievol brein". Academische Boekengids, March 2008 "Bijna dood". NRC Handelsblad editie zaterdag & cetera, 5/6 April 2008. "Geen wetenschap". NRC Handelsblad editie zaterdag & cetera, 5/6 April 2008. "Het slikken van XTC is bloedlink". NRC, 26/27 April 2008. Ingezonden brieven over artikel XTC, NRC, 3/4 May 2009 "Man wil man." Quest, July 2008 "Boodschappen van God". Feature article in De Telegraaf, 4 October 2008 "Wij zijn onze hersenen." In: Themabijlage Onze Hersenen. Mediaplanet 2008. "Depression is associated with imbalance in genes that regulate the hypothalamic-pituitary-adrenal axis" In: Neuro-psychiatry Reviews 30 June 2008. "Laser dissection of depression" In Molecular Psychiatry 22 April 2008. "Het brein verdient beter". In: Status, October 2008, no. 12, year 17, pp. 11-13. "Dementie minder dankzij extra licht". NRC, 11 May 2008. "Brein Special" Speciaal nummer over de hersenen. Quest. 4 September 2008. "Licht en melatonine effectief bij Alzheimer". De Neuroloog 4, 2008. "Dick Swaab ontvangt Akademiepenning 2008". De Neuroloog 4, 2008 Reacties op Swaab's columns in de weekendedities van NRC Handelsblad, in NRC Handelsblad weekendeditie 6/7 september 2008 "Neuroloog Swaab wil 'uitburgeringscursus'. In: Relevant, NVVE, no. 3, July 2008 Selected by Jonathan Seckl for comment in F1000: "Gene expression analysis in the human hypothalamus in depression by laser microdissection and real-time PCR: the presence of multiple receptor imbalances. "De (onzekere) huisarts en de doodswens". NRC, 12 November 2008 "Verlichting bij dementie", Synaps, no. 67. "Verliefd Geheugen" - reactie op column Verliefd Brein. "Buikhuisen heeft toch gelijk" - Volkskrant, 13 February 2009. "Ophef over homobrein en hetero-hersenen" - Algemeen Dagblad, 26 February 2009 "Als homo word je geboren" - Humo, 26 February 2009 "Een kalm brein. Dat kun je zelf" - Mind Magazine, March 2009 "De aftakeling". In: Dag. Frits Abrahams, NRC Handelsblad 16 March 2009. "Afscheid Swaab". In: Kwesties. NRC Handelsblad weekendeditionn 4/5 April 2009 "Pak de PacMan". In: AMC Magazine, no. 3, March 2009 "Geheime codes". In: Explore, no. 1, February 2009 "NIN met slag en stoot naar honderdjarig jubileum." In Status, nr. 9, jaargang 18, juni 2009 "Een eeuw lang kronkels kijken". In: Akademie Nieuws, no. 102, June 2009 "Helderheid en openheid over doodswens in de psychiatrie." In: Relevant nr. 2, 2009. Het grootste compliment is: ik heb een gewoon leven nu. De Volkskrant, 18 July 2011 "Waar zit God in de hersens?" Het Parool, PS Weekend, 22 August 2009. "Sprookje", Column Aleid Truijens, De Volkskrant, 22 September 2009 "Meer klootzakjes in Nederland?" Humanistische Omroep, 12 November 2009 "Revela especialista de instituto holandés que es posible reactivar neuronas dañadas por el Alzheimer" La Jornada, 16 October 2009. "Opvoeden is geen sinecure." Spui 30 (alumnimagazine). February 2009 'Schuld". Column Jean-Pierre Geelen. De Volkskrant, 30 November 2009 "Uitburgering" in Medisch Contact, November 2009 "Wetenschappers over strenger straffen" NRC, 30 November 2009 "Hulp bepleit bij zelfdoding 70-plussers" NRC, 8 February 2010 165

"70-plus eist zachte dood." Het Parool. 9 February 2010 "Omgeving heeft ook stem in einde naaste" Trouw, 9 February 2010 "Laat oudere vrij in keus voor de dood." De Volkskrant, 13 February 2010 "Oog in oog met de laatste wil" VPRO tv guide of 27 February to 5 March, 2010 "Wat is ondraaglijk lijden?"nrc Handelsblad, Opinie en Debat, zaterdag/zondag 19/20 June 2010. "Hersenonderzoeker bij toeval" NRC Handelsblad, Rubriek 'Brieven', zaterdag/zondag 19/20 June 2010. "Hersenonderzoeker bij toeval 2" NRC Handelsblad, Rubriek 'Brieven', zaterdag/zondag 19/20 June 2010. "Het ik als kwebbeldoos" NRC Handelsblad, Rubriek Interview, zaterdag/zondag 19/20 June 2010. "Afscheidsrede Dick Swaab in het teken van de dood". Trouw, 18 June 2010 "Voltooid leven op de agenda gezet". In Human, lente 2010. "Pressure mounts for Dutch MPs to hold 'time to die'debate" British Medical Journal, 27 February 2010, vol. 340. "Wangedrag is meer dan biologie" Volkskrant, 10 juli 2010. "We weten niet waar we het over hebben". Column Marjoleine de Vos. NRC 5 July 2010. "De bokkensprongen van het brein verklaard." Book review of Dick Swaab's book: Wij zijn ons brein: van baarmoeder tot Alzheimer. In: Trouw, 27-09-2010. "Levenseindekliniek is een merkwaardig initiatief" Bert Keizer in Trouw, 14 August 2010. "Ons brein en de politiek" Column Marcel van Dam in de Volkskrant, 14 October 2010. Taboo Intersex Between the Genders. Thurn film, ZDF/Arte, 2010 Nederlands doorbraak in onderzoek naar Alzheimer. Parool 26 October 2010. Dutch researchers find very early signs of Alzheimer s. Dutch News.nl Hersenen zijn niet blauw of roze. NRC Handelsblad 28 October 2010. Belangrijke stap in strijd tegen Alzheimer. Nu.nl Gebruik toch je hersens in Advocatenblad, 12 november 2010 Ziel kent zijn eigen werkelijkheid. In Friesch Dagblad, 29 november 2010 De vrije wil is een prettige illusie. Psyche en Brein, december 2010 Ons brein is een godswonder. In Katholiek Nieuwsblad, 17 December 2010 Wij zijn ons brein van neurocalvinist Swaab. Iedereen leest by Margriet van der Heijden in NRC Next, 25 oktober 2010 Wij zijn meer dan ons brein by Herman van Praag, Trouw, Saturday 5 February 2011 Overvolle aula voor Swaab. In, Haarlems Dagblad, 28 January 2011 Het brein volgens Dick Swaab. Announcement of the tv special Profiel in tv guide Letter to the Editor in NRC Handelsblad 15 February 2011 Het handenschudden-incident. In Folia, issue 64, no. 21, 18 February 2011 Moeten er ook nog gedachten in? In: NRC Handelsblad, 1 March 2011 Waarnemen is nog geen denken. In: NRC Handelsblad, 31 March 2011 Baas in eigen brein? In: NRC Handelsblad, 31 March 2011 Wij zijn niet ons brein, kijk maar naar het Midden-Oosten: is hersenonderzoek wetenschap of ideologie? Vrij Nederland, 12 March 2011 The Neuro Calvinist who discovered the homo lobe In: The Low Countries. Arts and Society in Flanders and The Netherlands. Ze zijn er weer: de Zomergasten. In: Media, NRC Handelsblad, 14 June 2011. Amuzikaal zijn is de grote uitzondering. Door Henkjan Honing, Erik Scherder en Dick Swaab. In: De Volkskrant, 18 June 2011. Doodgaan met Dick Swaab. In: NRC Handelsblad, 22 August 2011. Wij zijn ons brein niet. In: NRC 5 August 2011. Are all men pedophiles? J.W. Production (this movie features an interview with Dick Swaab) Leven in de brouwerij. In: De Pers, 5 August 2011. Uren glimlachen en niets persoonlijks zeggen. In: Trouw, 3 August 2011. Swaab. In: Het Parool, 1 August 2011. We hebben lang geaarzeld om dit te tonen. In: Trouw, 26 August 2011. 25 Jaar snijden in hersenen voor wetenschap. In: ANP 26 August 2011. Zijn wij ons brein. In: NRC, 2 September 2011 De Hersenbank: de enige bank met hersenen. (on the 25th anniversary of the Netherlands Brain Bank) Parool, 17 September 2011. Vrije wil meet je niet met een hersenscan. In: De Volkskrant, 15 September 2011 Een goede tegenwerping heb ik nog niet gehoord. In: NRC Weekend, Saturday 5 November & Sunday 6 November 2011 Dick Swaab, 1967. In: De eerste stap in de wetenschap. Interviews met geleerden. Hans van Maanen. 166

Uitgeverij Boom, Amsterdam, 2011. 25 jaar Nederlandse Hersenbank. In: Mensen. issue 19, no. 5, October 2011 Swaab s question on brain evolution answered in Quest 101, p.44 Question asked of Swaab in Quest 101, p. 103. Chapter on Swaab in Aan het Werk. De opmerkelijke Joodse bijdrage aan naoorlogs Nederland. Auteur: André Agsteribbe, AMB Diemen, 2011. Reactie Dick Swaab op stelling Naema Tahir over pedofilie zichtbaar in scanner. Volkskrant 21 December 2011. Hersengymnastiek op museumfeestje. De Limburger, 16 January 2012. In Boek. Special over Het Brein, issue 9, no. 1, January/February 2012 Zaal TU/e veel te klein voor hersenprofessor. Peter van Vlerken, Eindhovens Dagblad, 27 February 2012 Het menselijk tekort. Column Wilma de Rek in De Volkskrant, 3 March 2012 Neurobioloog Dick Swaab op het Feest van de Filosofie. Nieuws, http://nieuws.kuleuven.be Aankondiging Publiekslezing te houden op 17 mei 2012 in China (in het Chinees, in Chinese krant op 15 mei 2012) Interview n.a.v. Publiekslezing gehouden op 17 mei 2012 in China (in het Chinees, in Chinese krant op 19 mei 2012) Blootstelling aan explosies kan leiden tot hersenziekte. De Volkskrant, 18 mei 2012. De vrije wil bestaat weer. Of toch niet? Trouw, 21 april 2012. Interview about children and alcohol. DVD for www.alcoholvrijkind.nl, 12 July 2012 Over boksen. In: Privé, week 25, 27 juni 2012 Over genialiteit. In: Spits, 5 juli 2012 Diepvriesvrienden (Frozen friends) In: Volkskrant magazine, 30 June 2012 Hot topics in het hersenonderzoek. DVD voor ISBW, 28 June 2012 Over Thought Leadership gesproken. In: Realities. Deutsche Bank Magazine. June 2012 Matters relating to Wij Zijn Ons Brein - book reviews/related events "Swaabs brein". Book review of Dick Swaab's book: Wij zijn ons brein: van baarmoeder tot Alzheimer. In: Elsevier, 25-09-2010. "De bokkensprongen van het brein verklaard." Book review of Dick Swaab's book: Wij zijn ons brein: van baarmoeder tot Alzheimer. In: Trouw, 27-09-2010. Het brein is wat wij zijn. Review van "Wij zijn ons brein" In: De Volkskrant, 02-10-2010. Review Wij zijn ons Brein in Arts en Auto, October 2010 Review Wij zijn ons Brein in Het Financieele Dagblad, 13 November 2010. Review Wij zijn ons Brein in De Groene Amsterdammer, 11 November 2010 Dick Swaab signeersessie Amstelveen op youtube.com/watch?v=smvst845wda Dick Swaab signeersessie Amstelveen in Amstelveens Nieuwsblad Review Wij zijn ons Brein in www.boeken.blogo.nl Review Wij zijn ons Brein by Piet van der Ploeg, Centrum Cognitieve Gedragstherapie, 15 October 2010 Review Wij zijn ons Brein. NRC Handelsblad, 29 October 2010 Review Wij zijn ons Brein. De Redactie, De Recensie, 7 December 2010 Review Wij zijn ons Brein. Relevant 4, 2010 Review Wij zijn ons Brein, Het Goede Leven, 3 december 2010 Review Wij zijn ons Brein, Psycholoog, 31 december 2010 Review Wij zijn ons Brein, Kraamsupport, 31 december 2010 Review Wij zijn ons Brein, Radio Stad Roosendaal, January 2010 Het bruisende brein. Review Wij zijn ons Brein, De Standaard, 14 January 2011 De Hersenhype ((Brains are Hot), In: NRC Weekblad, 29 January 2011, pp. 19-23. Review Wij zijn ons Brein in YN, issue 27, no. 1, February 2011, p. 13. Review Wij zijn ons Brein in Ons Erfdeel, Vlaams-Nederlands Cultureel Tijdschrift, February 2011, pp 84-91 Top 100 Certificate (Bestselling books) for Wij zijn ons Brein. CPNB. Dick Swaab koestert over het brein een al te absolute overtuiging. NRC Handelsblad, 22 April 2011. Review Wij zijn ons Brein, Ad Kaasenbrood, Maandblad Geestelijke Volksgezondheid 11/6. Book review Wij zijn ons Brein, Marian Henderson in Soft Secrets, Issue 11, no. 1, 2011 Book review Wij zijn ons Brein, De Staatskrant/De Buurtkrant, May 2011 Het brein is in. Review Wij zijn ons Brein. Sp!ts, August 15 August 2011 Book review Wij zijn ons Brein. It s all right, I m a doctor, by Douwe Draaisma. In: De Academische Boekengids, no. 88, September 2011 NS publieksprijs nomination for Wij Zijn Ons Brein. Ook China wil Geert Mak en Dick Swaab lezen. NRC, 2 September 2011 167

Mijn muziek zat er dus al vanaf het begin in. Interview met Janine Janssen. NRC Handelsblad, 20 October 2011 Review Wij zijn ons Brein in Academische Boeken Gids, nr. 89, November 2011 Brieven over Swaab. Tegenwerpingen. In: NRC Weekend, Saturday 26 November 2011/Sunday 27 November 2011. Hersenspinsel. Report on a discussion with Herman van Praag in the Jacobikerk, Utrecht. Elsevier, 11 Februari 2012 Warum Sport das Leben verkürzt. Review of the German translation of Wij zijn ons Brein, Kleine Zeitung, 1 January 2012. Hersenen Centraal. Performance with Prof. Chantal Kemner in the Public Library of Amsterdam, OBE Schrijver Live, 27 February 2012. Questions for the VWO (pre-university) Final Examination Philosophy based on Wij Zijn ons Brein. Interview voor het blad van het Istituto Nazionale di Neuroscienze over de Italiaanse vertaling van Wij Zijn ons Brein (Noi siamo il nostro cervello). 168