Assistant Professor of Psychiatry, Dalhousie University
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1 NAME: Cynthia CALKIN POSITION / TITLE: Assistant Professor of Psychiatry, Dalhousie University ADDRESS: Abbie J. Lane Building, Room Veterans Memorial Lane Halifax, Nova Scotia B3H 2E2 Office: (902) Fax: (902) [email protected] EDUCATION / TRAINING Diploma - Statistical Genetics: Probability and Statistical Inference - University of Washington Diploma - The Peer Review Process & Making Your Grant More Competitive - Dalhousie University FRCPC - Fellow - Psychiatry, Dalhousie University CCFP - Fellow - Family Practice - Dalhousie University Doctorate (M.D.) - Dalhousie University BSc (cum laude) - Dalhousie University USER PROFILE Disciplines Trained In: Psychiatry, Family Medicine Research Disciplines: Psychiatry Areas of Research: Mood Disorders, Neuroendocrine Diseases Fields of Application: Biomedical Aspects of Human Health, Pathogenesis and Treatment of Diseases Research Specialization Keywords: Bipolar Disorder, Medical Co-morbidity, Metabolic Syndrome, Psychiatry, Type 2 Diabetes
2 POSITIONS AND HONOURS Positions and Employment present Active staff psychiatrist, Capital District Health Authority, Halifax, Nova Scotia, Canada present Assistant Professor, Department of Psychiatry, Dalhousie University Lecturer, Department of Psychiatry, Dalhousie University Honors APA Physician s Recognition Award (Distinction) - American Medical Association 1992 Dr. Elizabeth Weld Memorial Award (Distinction) - Dalhousie University 1991 John George & Emily MacDougall Award (Distinction) - Dalhousie University 1990 John George & Emily MacDougall Award (Distinction) - Dalhousie University OTHER EXPERIENCE AND PROFESSIONAL MEMBERSHIPS Memberships/Credentials present International Group for the Study of Lithium treated patients - Member present Nova Scotia College of Physicians & Surgeons - Member present Royal College Physicians & Surgeons of Canada Certificant and Fellow present Canadian Psychiatric Association - Member present Canadian Medical Association Member 1995 present Canadian College of Family Practice - Member present Licentiate, MCCQE Part 1 - Medical Council of Canada American Board of Family Practice - Certificant 2
3 Research Support The risk and burden of insulin resistance in bipolar disorder. Brain and Behavior Research Foundation (formerly NARSAD), principal investigator, $59, Sub-phenotyping bipolar disorder as a function of diabetes co-morbidity. Capital Health Research Fund, principal investigator, $14,949 International Collaboration Activities Metabolic dysfunction in depression- biochemical and anthropometric markers and their relationship with cognitive functioning International collaboration with Dr Dorota Łojko, PI- Researcher-Poland present International Group for the Study of Lithium treated patients (IGSLi) - IGSLi Member & researcher - Germany present Pharmacogenomics of mood stabilizer response in bipolar disorder international study with Dr. John Kelsoe, PI - Researcher - California Mentoring Activities present As assistant professor (Dalhousie University) - 6 mentorees As Lecturer (Dalhousie University) - 11 mentorees Publications (Peer reviewed only) Cynthia V. Calkin, Martina Ruzickova, Rudolf Uher, Tomas Hajek, Claire M. Slaney, Julie S. Garnham, M. Claire O Donovan, Martin Alda: Insulin resistance and outcome in bipolar disorder. British Journal of Psychiatry, May 2014, In Press Tomas Hajek, Cynthia Calkin, Ryan Blagdon, Claire Slaney, Rudolf Uher, Martin Alda: Insulin resistance, diabetes mellitus and brain structure in bipolar disorders? Neuropsychopharmacology, May 2014, In Press. Tomas Hajek, Cynthia Calkin, Ryan Blagdon, Martin Alda: Type 2 diabetes mellitus - a potentially modifiable risk factor for neurochemical brain changes in bipolar disorders. Biological Psychiatry. Nov 2013 Epub ahead of print. 3
4 Mirko Manchia, Martin Alda, Cynthia V. Calkin: Repeated erythromycin/codeine-induced psychotic mania. Clin Neuropharmacol (5): Mirko Manchia Cynthia V. Calkin Martin Alda: Assessment of Response to Lithium Maintenance Treatment in Bipolar Disorder: a Consortium on Lithium Genetics (ConLiGen) Report. PLoS ONE ;8(6):e Cynthia V. Calkin, David Gardner, Thomas Ransom, Martin Alda: The relationship between bipolar disorder and type 2 diabetes: more than just comorbid disorders. Annals of Med : Cynthia V. Calkin, Martin Alda: Beyond bipolar guidelines: Practical issues in long term treatment with lithium. Can J Psych (7): Cynthia Calkin, Caroline van de Velde, Martina Ruzickova, Claire Slaney, Julie Garnham, Tomas Hajek, Claire O Donovan, Martin Alda: Can body mass index help predict outcome in patients with bipolar disorder? Bipolar Disorders (6): Martin Alda, Tomas Hajek, Cynthia Calkin, Claire O Donovan: Treatment of bipolar disorder: New perspectives. Ann Med (3): Cynthia V. Calkin, Carlo G. Carandang: Certain eating disorders may be a neuropsychiatric manifestation of PANDAS: Case report. J Can Acad Child Adolesc Psychiatry (3): Abstracts C. Calkin, M. Ruzickova, C. Slaney, J. Garnham, R. Uher, C. O Donovan, M. Alda. Insulin resistance: An occult, modifiable risk factor for refractory bipolar disorder. International Journal of Neuropsychopharmacology Supplement. C. Calkin, M. Ruzickova, C. Slaney, J. Garnham, C. O Donovan, T. Ransom, M. Alda. Are comorbid insulin resistance and type II diabetes risk factors for refractory bipolar illness? European Neuropsychopharmacology supplement (ENP). C. Calkin, C. Slaney, M. Ruzickova, J. Garnham, C. O Donovan, T. Ransom, M. Alda. The risk of insulin resistance and type 2 diabetes mellitus in bipolar disorder. International College of Neuropsychopharmacology supplement (CINP). Presentations C. Calkin, M. Ruzickova, C. Slaney, J. Garnham, R. Uher, C. O Donovan, M. Alda. Insulin resistance: An occult, modifiable risk factor for refractory bipolar disorder. International Journal of Neuropsychopharmacology Supplement. Presented CINP Vancouver, 23 June
5 C. Calkin, M. Ruzickova, C. Slaney, J. Garnham, R. Uher, C. T. Hajek, C. O Donovan, M. Alda. Co-morbid insulin resistance and type II diabetes predict chronic course of bipolar illness and poor response to lithium. Presented American Psychiatric Association (APA) Annual Meeting, New York City, 4 May C. Calkin, M. Ruzickova, C. Slaney, J. Garnham, C. O Donovan, T. Ransom, M. Alda. Are comorbid insulin resistance and type II diabetes risk factors for refractory bipolar illness? European Neuropsychopharmacology supplement (ENP), presented ECNP Barcelona, Spain, 6 Oct C. Calkin. Comorbid insulin resistance and type II diabetes may predict poor response to lithium International Group for the Study of lithium treated patients (IGSLi) annual meeting. Dresden, Germany, 6 September 2013 C. Calkin. The role of early life adversity in bipolar disorder and diabetes. Presented as invited guest. Women in Psychiatry meeting, Halifax, NS. 20 Nov 2012 C. Calkin. Metabolic abnormalities in bipolar disorder. Presented as invited guest New Brunswick Psychiatric Association Annual Meeting, Moncton, NB. 2 November 2012 C. Calkin, C. Slaney, J. Garnham, M. Ruzickova C. O Donovan, T. Ransom, M. Alda The risk and burden of insulin resistance and type 2 diabetes in bipolar disorder International College of Neuro-Psychopharmacology (CINP) World Congress in Stockholm, Sweden 3-7 June C. Calkin. Bipolar Disorder and Metabolic Factors: Type 2 Diabetes, insulin resistance and metabolic syndrome. The Nova Scotia Bipolar Peer Support Alliance - Halifax Chapter presentation: 23 April C. Calkin. Medical Co-morbidity in bipolar disorder and the role of early life adversity. Clinical Academic Rounds Dalhousie University, Halifax, NS. 4 April C. Calkin, C. Van de Velde, M. Ruzickova, C. Slaney, J. Garnham, T. Hajek, C. O Donovan, M. Alda. Can body mass index help predict prognosis and outcome in bipolar disorder? 2011 WFSBP Annual Meeting. Prague, Czech Republic. 29 May- June 2, C. Calkin. Diabetes and metabolic factors in bipolar disorder. Presented as invited guest, 2010 International Group for the Study of lithium treated patients (IGSLi) annual meeting. Sardegna, Italy 1 October 2010 C. Calkin. Sub-phenotyping Bipolar Disorder as a Function of Diabetes Co-morbidity. Canadian Institute of Health Research: New Principal Investigators Meeting, Jackson Point, Canada, November
6 C. Calkin, C. Van de Velde, M. Ruzickova, C. Slaney, J. Garnham, T. Hajek, C. O Donovan, M. Alda. Body mass index correlates of bipolar disorder: Can BMI help predict prognosis and outcome? 2009 WFSBP Annual Meeting. Paris, France. 28 June - 2 July C. Calkin, C. van de Velde, M. Ruzickova, C. Slaney, J. Garnham, T. Hajek, C. O Donovan, M. Alda. Body mass index correlates of bipolar disorder: Can BMI help predict prognosis and outcome? Presented 2009 Society of Biological Psychiatry (SOBP) Annual Meeting Vancouver, Canada May C. Calkin, C. Van de Velde, C. Slaney, J. Garnham, M. Růžičková,T. Hájek, C. O Donovan, M. Alda. Body mass index correlates of bipolar disorder: Can BMI help predict prognosis and outcome? 2008 APA Annual Meeting in Washington, DC, USA. 3-8 May
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