Organ on Chip. Developing tools for new, better and personalized therapies. Organ on Chip

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1 Organ on Chip Developing tools for new, better and personalized therapies Organ on Chip

2 Organs on Chip for tailor-made medicine Professor Albert van den Berg received his PhD at the University of Twente in 1988 on the topic of chemically modified ISFETs. From he worked in Neuchatel,Switzerland, at the CSEM and the University (IMT) on miniaturized chemical sensors. From 1993 until 1999 he was research director of Micro Total Analysis Systems (microtas) at MESA+, University of Twente, a topic that was extended to Miniaturized Chemical Systems (MiCS) in In 1998 he was appointed as part-time professor Biochemical Analysis Systems, and later in 2000 as full professor on Miniaturized Systems for (Bio) Chemical Analysis in the faculty of Electrical Engineering, embedded in the MESA+ Institute for Nanotechnology. In 2002 he received the Simon Stevin Master award from the Dutch Technical Science foundation (STW). In 2003 he was appointed as captain of the Nanofluidics Flagship within the national nanotechnology program Nanoned. In 2005, he carried out sabbatical research at the La Jolla Institute for Allergy and Immunology in San Diego, U.S.A., which led to obtain additional support from an Advanced Research Grant from ERC in His research interests focus on microanalysis systems and nanosensors, nanofluidics and single cells on chips, with applications in health care and the environment. Van den Berg is a board member of the Royal Dutch Academy of Sciences (KNAW), the Dutch Health council, board member of the Chemical and Biological Microsystems Society, member of the Dutch chemical society (KNCV) and associate editor of the journal Lab on a Chip. He has co-authored over 280 peer reviewed papers and over 15 patents, and has been involved in more than five spinoff companies. Albert van den Berg University Professor, University of Twente In 2009 he was awarded the most prestigious Dutch scientific award - the NWO/Spinoza Prize for his key achievements in the Microsystems field, and its application to development of new medical devices. In 2010 he was appointed University Professor at the University of Twente, and in 2011 he became Distinguished Professor at the South China Normal University. In 2014 he was appointed as scientific director of the MIRA institute for biomedical technology at the University of Twente.

3 Christine Mummery is Professor of Developmental Biology at Leiden University Medical Centre in the Netherlands and head of the Department of Anatomy and Embryology. Her research concerns heart development and the differentiation of pluripotent human stem cells into the cardiac and vascular lineages and using these cells as disease models, for safety pharmacology, drug discovery and future cardiac repair. She is a member of the Royal Netherlands Academy of Science (KNAW), and board member of ISSCR, the KNAW and the Dutch Medical Research Council (ZonMW). She was recently awarded the Hugo van de Poelgeest Prize for Animal Alternatives in research. She co-authored a popular book on stem cells Stem Cells: scientific facts and Fiction in 2011 (2nd edition 2014) and is editor in chief of the ISSCR journal Stem Cell Reports. Christine Mummery Professor of Developmental Biology at Leiden University Medical Centre Human stem cells as the new patient Live cell imaging: formation of a blood vessel. Endothelial-pericyte (in red) interactions in microfluidic channels (source LUMC, UTwente)

4 Partners in this program Contact details Prof. dr. ir. Albert van den Berg University of Twente P.O. Box AE Enschede

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