Japan Association for International Chemical Information (JAICI)

Japan Association for International Chemical Information (JAICI)

Our Mission To contribute to the Advancement of the Science and Technology of Japan and the rest of the World via the Flow of Chemical Information Vision for Tomorrow PREFACE With the explosion of knowledge in the 21st century, we are deluged by a constant flood of new information on science and technology emerging from every corner of the globe. The key to success, in this vast sea of information, is to effectively retrieve and use relevant information for the support of R&D, intellectual property management, and the many processes of manufacturing. No single person can expect to find and extract the most useful information on science and technology from the staggering amounts of information published. This is where a secondary information database comes into play. Yet to truly function as intended, a secondary database must effectively collect information, process and compile it in an easily accessible form, and offer comprehensive functionality to help users reach and analyze the information of the most use to them. Without these capabilities, a database will offer no true value. Message to JAICI Taking information and transforming it into solid knowledge. Life is too short to read everything worth reading. A scientist nowadays needs some sort of mechanism to sift through the vast body of literature published and come up with the papers really worth reading. CAS serves up information of the highest reliability and quality - information I hope will last forever. Dr. Ryoji Noyori 2001 Nobel Laureate in Chemistry To accomplish its mission of "promoting the progress of science and technology in Japan and the rest of the world as a portal of chemical information," JAICI has been working as an information support center dedicated to the growth of science and technology in Japan, especially in the field of chemistry. Our services include access to STN for integrated searches of various databases, access to SciFinder (CAS) for use by researchers, maximum customer support through workshops and help desk services, and access to scientifically valuable information, such as crystal structures. We also offer retrieval and search services backed up by years of accumulated knowledge and experience. Over the decades since its founding, JAICI has expanded its field of activities in a close partnership with the US Chemical Abstracts Service (CAS). The growing body of domestic information resources we provide as an information portal from Japan to the rest of the world now encompasses more than half of the patent and journal literature published in Japan. We are fully committed to promoting the development of science and technology for future generations by providing vital information and truly useful services to customers from various disciplines and industries. Kazuhiko Onuma President, Japan Association for International Chemical Information 1 Japan Association for International Chemical Information (JAICI) Japan Association for International Chemical Information (JAICI) 2

Database Services Transforming chemical information from around the world into chemical knowledge for Japan We provide companies and universities in Japan with information on science and technology from around the world. SciFinder search results We provide access to SciFinder, an information search tool indispensable for researchers who need to produce fruitful results in order to discover new phenomena and innovate new technologies. SciFinder is an online search service that allows researchers to retrieve information from disciplines such as chemistry, pharmaceuticals, biochemistry, physics, and engineering. SciFinder links users to comprehensive science information from the CAS databases, the world's largest collection of research information in science and technology. SciFinder's powerful yet flexible search interface delivers speedy and accurate results. STN search results As the STN-Tokyo Service Center, we provide access to STN, an online tool for retrieving science and technology information from all over the world, to customers in Japan STN, the online database service jointly operated by CAS (US) and FIZ Karlsruhe (Germany), provides information on science and technology. STN links to a wide range of databases covering various fields of science and technology around the world, including journal/patent databases, substance databases, full-text patent databases, numerical databases, and more. STN Express analysis results Chemical Abstracts Service Chemical Abstracts Service (CAS), a division of the American Chemical Society (ACS), is the world's authority on chemical information. CAS databases are created and quality-controlled by experts from various disciplines and used by chemical and pharmaceutical companies, universities, governmental organizations, and patent offices around the world. FIZ Karlsruhe FIZ Karlsruhe, the STN Service Center in Europe, is a scientific information institution supported by the Federal Republic of Germany and Federal States. Since its establishment in 1977 as an information service provider to universities and businesses, FIZ Karlsruhe has been building and offering high-quality databases in a wide range of disciplines for the support of R&D and commercial operations internationally. STN AnaVist analysis results STN Viewer patent evaluation results STN Express / STN on the Web STN Express is a software package with graphic capabilities and a range of functions for efficient use of STN, including structure searching. STN on the Web gives web-browser access to STN. STN AnaVist STN AnaVist is a powerful interactive analysis and visualization application capable of visualizing patterns and trends in research and analyzing search results from scientific literature and patents in various ways. STN Viewer STN Viewer is a tool to support your patent evaluation from various viewpoints. You can seamlessly access the full text of patent documents by importing the answer sets (patent) obtained through STN Express or STN on the Web into STN Viewer. STN Easy STN Easy gives users web access to major databases on STN not via command language, but via menu selection in Japanese. Use this service to search a wide range of information on journal and patent literature in science and technology, pharmaceuticals, chemicals, and so on. 3 Japan Association for International Chemical Information (JAICI) Japan Association for International Chemical Information (JAICI) 4

User Support Linking you to information of true value We provide support and training to everyone in need of information, from info-pros to scientists. Workshop to promote the effective use of online search services STN workshops and seminars We hold monthly workshops in Tokyo and Osaka to train users in basic skills in using STN. We also hold workshops and seminars to promote more effective ways to use STN. Prominent, among these, are various seminars on specific topics and "STN refresh seminars" designed to introduce practical search techniques. Workshops with hands-on training SciFinder workshop We can visit your place of business or university to provide workshops customized to your particular needs. These can range from introduction seminars for beginners to new-feature presentations for advanced users. e-learning We provide e-learning tools for remote users unable to attend our workshops or as a resource for inhouse training. You can learn how to use STN and SciFinder by video or on the Web. Seminars introducing database enhancements Expert help desk staff Help desk support from technical experts Our expert staff will quickly answer your technical questions. Support information is updated on the website To keep our customers updated with the news and latest information on STN, we are sending a printed newsletter, STNews (Japanese Version), and an electronic newsletter, STNewsline, to registered users. The latest information on SciFinder is sent to users through the SciFinder Newsletter. The Latest Information section on the top page of our web site presents information on the recent enhancements of JAICI services such as STN and SciFinder, and on schedules for workshops, seminars, and exhibitions as soon as they are fixed. Technical documentation on our services is also available from our web site. Obtaining CA Index Names and assigning CAS Registry Numbers to your chemical substances Chemist Consultation - Substance Identification We help customers to get CA Index Names in accordance with CAS nomenclature and CAS Registry Numbers required for exporting chemical substances to overseas. JAICI homepage Inventory Expert Service Inventory Expert Service (IES) provides CA Index Name and CAS Registry Number applicable for Premanufacture Notification (PMN) submission to the inventory registration under the Toxic Substances Control Act (TSCA) issued by the US Environmental Protection Agency (EPA). Registry Lookup Service When customers request it, we have CAS staff retrieve the REGISTRY file for substances using chemical names or CAS Registry Numbers. Scientific and Technical Information Network STN STN is an online database service that provides global access to published research, journal literature, patents, structures, sequences, properties, and other data. We help you disseminate information on your products in catalogs. CHEMCATS (Chemical Catalogs Online) registration service CAS independently operates CHEMCATS, a catalog database containing commercially available chemicals from all over the world. We help you register your product information in CHEMCATS for free and make the catalog information accessible via STN, STN Easy, SciFinder. 5 Japan Association for International Chemical Information (JAICI) Japan Association for International Chemical Information (JAICI) 6

Database Building Building high-quality databases JAICI has been providing Japanese science and technology information to the CAS databases since 1982. JAICI's trained chemical experts analyze Japan's state-of-the-art science and technology information and rapidly transmit it to the world through CAS databases. Abstracting and Indexing for literature searching JAICI analysts prepare abstracts and index entries for Japanese patents, enabling search and retrieval with high accuracy. Quality assurance is conducted by the same standards as for CAS, ensuring high quality. CAS databases cover broad areas from neutrinos and nanotechnology to astrophysical phenomena such as the Big Bang with excellent timeliness; for early cases, several days after the patent publication. Indexes and abstracts from Japanese literature covered in the CAS database Code-Indexing for variable group-containing chemical structure searching JAICI analysts do the code-indexing for Markush structures (general structures having variable groups) described in patents for structure searching. The coding requires meticulous attention and mathematical thinking. Its quality is highly rated by CAS as well. Providing citation information for citations searching JAICI provides English translation of examiners' citations in examined Japanese patents within 3 days to CAS. The translated citations help database searching of patent information, etc. Plaque awarded by CAS to celebrate 1 millionth indexing and abstracting by JAICI 10 28 m 10 2 m 10-18 m 10-9 m 10-5 m 10 0 m Big Bang Transition of the number of substances registered in the REGISTRY file Total of 144,000,000 Indexing and abstracting by chemical experts Elementary Particles Nano technology Red blood cells Human Tall Buildings Protein and nucleic acid sequences Chemical substances other than sequences Total of 100,000,000 To expand our services and enable the more convenient and streamlined use of information, we apply our Machine Translation technology specialized in chemistry to the CAS services (English-to-Japanese and Japanese-to-English). Every single document is reviewed by experts to prepare complete information for the Registry file. The number of registered substances has been increasing exponentially since the 21st century. Chemical substances other than sequences: 78,000,000 English-to-Japanese Machine Translation of titles in CAplus We translate all of the titles in CAplus in cooperation with CAS (about 8,000 titles per day). Japanese-to-English Machine Translation of Kokai patent documents and Utility Models We also feed machine-translated English titles and abstracts of Japanese Kokai patent documents and Utility Models into CAplus as quick reports. 1970 1980 1990 1995 2000 2004 2008 2013 CAplus titles in Japanese CA Lexicon Japanese language support capability for CA Lexicon We have also prepared a Japanese version of the CA Lexicon data to help you search technical terms in Japanese. 7 Japan Association for International Chemical Information (JAICI) Japan Association for International Chemical Information (JAICI) 8

Fact Database & Software Meeting diversified information needs Our databases and software support researchers in science. Our service gives you full access to databases on crystal structure, mass spectrum, and countless other forms of chemical information. Cambridge Structural Database (CSD) The CSD is a global repository of validated crystal structure data for organic and metal-organic compounds. A comprehensive set of tools and derived databases facilitate diverse advanced research applications by allowing users to investigate molecular structures, intermolecular interactions, and crystal packing. CSD Inorganic Crystal Structure Database (ICSD) The ICSD contains information and X-ray diffraction data on the crystal structures of elements and inorganic compounds such as minerals, ceramics, and intermetallics. Metals and Alloys Crystallographic Database (CRYSTMET) The CRYSTMET contains information on the crystal structures of metals such as alloys, intermetallics, and metals containing minerals. ICSD GOLD Suite Our software helps researchers perform crystallographic analyses and analyses in the life sciences to support research goals such as the molecular design of pharmaceuticals. Protein-Ligand Docking Software (GOLD Suite) A program for protein-ligand docking using a genetic algorithm. Protein-Ligand Complex Search Software (Relibase+) A program to search, display, and analyze crystal structures retrieved from an integrated database of PDB (Protein Data Bank) and in-house data. An application for structure solution from powder diffraction data (DASH) A standard software package for solving crystal structures based on powder diffraction data. Cambridge Crystallographic Data Centre CCDC The Cambridge Crystallographic Data Centre (CCDC), UK, is a not-forprofit organization best known for its work as the database builder of the Cambridge Crystallographic Database (CSD). CCDC has expanded its activities into software development in the lifesciences and supports the research and development activities of scientists worldwide. NIST11 CCDC's DASH Seminar Other Databases NIST Mass Spectral Database (NIST11) The most reliable database of information on electron ionization mass spectra (available on CD-ROM). Science of Synthesis (a reference work for methods in organic synthesis) A web-based database of information on standard methods of organic synthesis. Chemical Dictionaries Our chemical dictionaries contain information on chemicals published in the literature (a web-based service partly available on DVD). The Combined Chemical Dictionary The Combined Chemical Dictionary is made up of the following four dictionaries. Dictionary of Natural Products Dictionary of Organic Compounds Dictionary of Inorganic/Organometallic Compounds Dictionary of Drugs CRC Press Taylor & Francis Group User Support We help our users through a variety of support services and seminars to encourage the effective use of JAICI databases and software. 9 Japan Association for International Chemical Information (JAICI) Japan Association for International Chemical Information (JAICI) 10

Search Service Sophisticated Eyes to Navigate Tomorrow Our services are a strong support for your patent and technology research in chemistry. IP information center (SHIPS) offers search services to support your intellectual property (IP) strategies. In 2011 we launched a search service to support the IP strategies of customers. In our capacity as a registered search organization of the Japan Patent Office, we can perform prompt and precise research based on our accumulated knowledge in STN search and our experience and skills in CA indexing. Main fields of search Pharmaceuticals Organic Chemistry Polymers Inorganic Chemistry Life Science Nanotechnology Biotechnology Patent search service Patent search is required in every phase of product development. The SHIPS search services meet your needs with a high level of scientific knowledge and experience. Flow chart of product development and research timing Prior-art Search Patent Infringement Search Patent Infringement Search Patent Infringement Search Patent Infringement Search Planning R & D Design Manufacture Sale Export / Import State-of-the-art Search Prior-art Search State-of-the-art Search Patent Application Request for examination Infringement Warning Substance-related search service Retrieve and provide information on chemicals, nucleic acids, proteins, and other substances. Proxy search service Retrieve information using search strategies and keywords of the customer's choosing. SDI service (Selective Dissemination of Information) Periodically deliver updated information on topics a customer chooses. Invalidity search SHIPS Science, Humanity, and Intellectual Property Service SHIPS is the nickname for this service and the department in charge. the Japan Patent Office Recognized as a registered search organization of the Japan Patent Office, JAICI is helping to construct an "IP-oriented nation" through its prior-art search service. Impelled by the need to speed up the patent examination process, the Japan Patent Office is promoting outsourcing of prior-art search. As a leading organization authorized to conduct prior-art searches in Category 30* organic compounds, JAICI is conducting prior-art search using STN for chemical structures. In light of the profound knowledge and experience required in chemistry and organic synthesis, researchers are mostly veterans skilled in organic chemistry. Category 30 is one of the 39 categories applied to technology. It encompasses patents for organic compounds used for pharmaceuticals, agricultural chemicals, electronic materials, and so on. Flow of a patent examination Patent Office Examiner's work Patent to be examined Examination Granted Refused Outsourcing Category 30 organic compounds Submission Explain face-to-face JAICI Patent Analysis Div. Searcher's work Understanding the contents Search STN chemical structure search (CAS databases) Patent office search system (Japanese patent) Report preparation 11 Japan Association for International Chemical Information (JAICI) Japan Association for International Chemical Information (JAICI) 12

Association Profile About Us Association Profile Structure Name Address Foundation Members (As of April 1, 2014) General Incorporated Association, Japan Association for International Chemical Information Acronym: JAICI Nakai-Building, 6-25-4 Honkomagome, Bunkyo-ku, Tokyo 113-0021, Japan 1971 (Corporate Entity authorized in July 1975; Transition to a General Incorporated Association registered in April 2011) President: Kazuhiko Onuma Regular members (Category 1) The Society of Chemical Engineers, Japan; Japan Technical Association of the Pulp and Paper Industry; Japan Explosives Society; The High Pressure Gas Safety Institute of Japan; The Society of Polymer Science, Japan; Japan Society of Colour Material; Catalysis Society of Japan; The Japan Petroleum Institute; The Society of Fiber Science and Technology, Japan; The Electrochemical Society of Japan; The Japan Institute of Energy; The Chemical Society of Japan; The Crystallographic Society of Japan; The Society of Rubber Science and Technology, Japan; The Society of Photography and Imaging of Japan; The Japanese Biochemical Society; The Society for Biotechnology, Japan; The Ceramic Society of Japan; The Geochemical Society of Japan; Japanese Society of Tribologists; Japan Society for Bioscience, Biotechnology, and Agrochemistry; The Japan Society for Analytical Chemistry; The Pharmaceutical Society of Japan; The Society of Inorganic Materials, Japan; and The Society of Synthetic Organic Chemistry, Japan Regular members (Category 2) Asahi Kasei Chemicals Corporation; Ajinomoto Co., Inc.; Astellas Pharma Inc.; Ube Industries, Ltd.; Kyowa Hakko Kirin Co., Ltd.; KURARAY CO., LTD.; KUREHA CORPORATION; JSR Corporation; Showa Denko K.K.; Sumitomo Chemical Company, Limited; DAIICHI SANKYO COMPANY, LIMITED; Toray Industries, Inc.; Nippon Kayaku Co., Ltd.; Nippon Soda Co., Ltd. FUJIFILM Corporation; Mitsui Chemicals, Inc.; Mitsubishi Chemical Corporation; MOCHIDA PHARMACEUTICAL CO., LTD.; and Lion Corporation. History General Meeting/ Board of Directors President Operating Directors Information Services and Marketing Div. Document Analysis Div. Information Technology Div. Patent Analysis Div. IP Information Center (SHIPS) Data Information Dept. Corporate Planning Dept. Business Administration Div. Information Services and Marketing Div. : Sales & Marketing, contract, and user support for database services such as STN and SciFinder Document Analysis Div. : Analysis of chemical information (prepares English abstracts and indexes of patents and provides them to CAS) Information Technology Div. : Support for the Association's work-related IT and support and research for machine translation Patent Analysis Div. : Prior-art searches for patent examinations (for Category 30, contract work as a Patent Office-registered search organization) IP Information Center (SHIPS) : Search services for patent and technology research Data Information Dept. : Provision of crystallographic and property databases and molecular design/drug discovery support tools Corporate Planning Dept. : Project planning and budget set-up, audits on operations, personnel management, and recruitment Business Administration Div. : General affairs, accounting, and public relations Workshop offices Tokyo Merino Rikugien Bldg. 2F, 1-3-1 Komagome, Toshima-ku, Tokyo 170-0003, Japan Osaka Senri Life Science Center, 1-4-2 Shinsenri-Higashimachi, Toyonaka-shi, Osaka 560-0082, Japan To Otsuka Hakusan Street To Sugamo Toei Mita line JR Yamanote line Rikugien No.2 Mizuho Bank Shinobazu Street Toei Subway Sengoku St. Exit KomagomePolice St. To Oji Hongo Street To Hongo Tokyo Metro Namboku Line JR Komagome St. Toei Bus Terminal Tokyo Metro Komagome St. Exit No.1 Kamifuji-mae intersection Koban JAICI workshop office (Merino Rikugien Bldg. 2F) JAICI (Nakai Bldg.) To Tabata To Sendagi 1968 The American Chemical Society (ACS) asks the Chemical Society of Japan (CSJ) to cooperate in the establishment of an organization for CAS data entry. 1969 The Council for Science and Technology (under the then Prime Minister's Office) dispatches a delegation to visit CAS for a science and technology information survey. The CSJ establishes the Special Committee for Chemical Information. 1970 The CSJ and related associations decide to establish a council for chemical information. 1971 The Japan Council for International Chemical Information is established. 1975 Approved as an incorporated association jointly operated by the Ministry of Education, Science and Culture and the Prime Minister's Office (Science and Technology Agency); renamed the Japan Association for International Chemical Information (JAICI). 1977 Signs a comprehensive cooperation agreement with CAS. 1980 Appointed as the exclusive agent for CAS in Japan; starts the CAS Online service. 1982 Starts inputting data into the CAS database. 1983 CAS/ACS and FIZ Karlsruhe sign STN operation agreement. 1984 Appointed as a service center for STN in Tokyo. 1987 The STN Tokyo Service Center is transferred to the Japan Information Center for Science and Technology (now the Japan Science and Technology Agency (JST)) and signs an agency agreement with JICST. 1995 Starts the SciFinder service. 1998 Starts the SciFinder Scholar service. 2002 Starts a joint operation of STN Tokyo Service Center with JST. 2005 Starts activities as a registered search organization for the Japan Patent Office. 2007 Starts the exclusive operation of STN Tokyo Service Center. 2011 Starts search services for patent and technology. Transition to a General Incorporated Association, Japan Association for International Chemical Information, authorized under the new law. 13 Japan Association for International Chemical Information (JAICI) Japan Association for International Chemical Information (JAICI) 14