Building Technologies. The APOGEE Compliance Solution for FDA-Regulated Facilities



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Building Technologies The APOGEE Compliance Solution for FDA-Regulated Facilities

PART 1+1=11: Siemens combines innovative technology + professional services to create the best total solution for Part 11 compliance. COMPLIANCE

Turn Part 11 compliance into a competitive advantage The APOGEE Compliance Solution for FDA-Regulated Facilities not only provides a traceable, secure and reliable facility information management system it helps you minimize operating costs, increase productivity and get to market faster. Combining innovative technology with professional services, we help you every step of the way with consulting, training, compliance analysis services and engineering support. The APOGEE Compliance Solution gives you end-to-end monitoring and control over facility conditions and data in your manufacturing operation, including data security, electronic signatures, audit trails, record/signature linking, system/device checks, ease of validation and integration with third-party systems. This ensures that your facility meets cgmp requirements as well as current regulations governing electronic records and signatures. The APOGEE Compliance Solution delivers tangible ROI benefits: Meet the electronic records and signatures requirements of 21 CFR Part 11 and maintain a traceable, reliable and secure information management system. Meet 21 CFR Parts 210/211 (cgmp) requirements as applied to the Building Automation System. Establish a basis for a life cycle approach per GaMP guidelines. Ensure the quality of environmental conditions in critical areas. Provide a safe and healthy work environment to minimize risk and liability. Improve staff productivity by developing a turn-key operation through integration of third-party systems and components. Minimize operational costs through monitoring and control of environmental, equipment and utility conditions. Provide a secure environment to protect staff, research integrity, product and processes.

The APOGEE Compliance Solution for FDA-Regulated Facilities Structured around the APOGEE Building Automation System, our bundled compliance solution enables you to electronically capture building operation and environmental condition records and their associated signatures in a secure format to achieve and maintain compliance with 21 CFR Part 11. Unlike competitive systems, the Siemens solution was designed to operate with its APOGEE Building Automation System from the ground up. So you get a completely integrated solution, supported and serviced by a single reliable source.

The APOGEE Compliance Solution provides a complete life cycle approach to facility automation and compliance that includes a full array of technology and services solutions. A complete facility life cycle solution

Engineered solutions Building automation for centralized facility management and control BUILDING AUTOMATION AND HVAC CONTROLS SECURITY INTEGRATION OF CRITICAL SYSTEMS AND DEVICES ALARMING/ ALARM ESCALATION REMOTE NOTIFICATION WEB-BASED ACCESS At the core of our compliance solution is the APOGEE Building Automation System, a sophisticated building automation solution that provides comprehensive monitoring and control capabilities for critical facility conditions. The APOGEE Building Automation System supports regulatory compliance by ensuring the integrity of electronic records throughout their entire life cycle from the point of creation to the end of a record s useful life. With its advanced architecture, the APOGEE Building Automation System also enables integration with third-party BAS components and software through LonWorks, BACnet or custom drivers and interfaces. This means you can monitor, control and document all facility subsystems and devices from a single workstation while maintaining full regulatory compliance. This level of integration helps boost efficiency, lowers costs and reduces risks in your facility. TECHNOLOGY (MEETING THE TECHNOLOGICAL ELEMENTS OF 21 CFR PART 11) Information management Powerful, intuitive access to facility control data REAL-TIME MONITORING ALARM INFORMATION MANAGEMENT DATA TRENDING DATA ARCHIVING REPORTING WEB-BASED ACCESS The APOGEE Building Automation System provides simple, centralized access to facility system information through its Insight workstations. Facility managers, engineers, production managers, scientists and quality control professionals can all access, view and share information generated by the APOGEE Building Automation System. With our powerful archiving and reporting software, InfoCenter Suite, you can retrieve and manage voluminous amounts of historical data generated by new or existing control and management systems from a single building or an entire campus and generate reports for long-term data analysis. InfoCenter Suite also provides electronic signatures digital representations used to authorize or "sign" electronic reports. This means your entire compliance process can be electronic with little or no need for paper-based documents.

Assessment surveys Understanding where you are now BAS PART 11 COMPLIANCE: GAP ANALYSIS BAS VALIDATION: CRITICAL SYSTEM AND COMPONENT IMPACT ASSESSMENT To help you understand the current conditions of your facility s systems and develop a plan to address your needs, Siemens provides assessment surveys. An assessment survey analyzes the critical functions of your manufacturing facility to identify potential regulatory and efficiency issues. Our interdisciplinary team identifies those processes that are currently successful as well as areas in need of improvement and targets solutions for maximum benefit. These comprehensive assessments not only provide you with a thorough gap analysis or benchmark, but also form the basis for developing a strategic plan that will guide you in achieving your facility performance goals. SERVICES (MEETING THE PROCEDURAL ELEMENTS OF 21 CFR PART 11) Service solutions Maintaining the established state of control CUSTOMER SUPPORT SERVICES FACILITY INFORMATION SERVICES COMPLIANCE SERVICES TECHNICAL SERVICES PERFORMANCE UPDATES We can ensure your day-to-day operations are maintained to established standards on a 24/7 basis. With over 100 field offices across North America, our local service technicians are highly experienced and easily accessible to provide quality service when you need it. Siemens Building Technologies offers a full complement of services including Customer Support, Compliance Services, Facility Information Services and a wide range of Technical Support Services to keep your systems up and running now and in the future.

Customer support services Education services Application & technology consulting Operator coaching Onsite building performance specialist Facility information services Environmental reporting and consulting InfoCenter Suite custom report design and creation InfoCenter Suite system administration InfoCenter Suite user training Data Migration Technical support services Automation controls analysis and optimization Business protection and recovery services Control loop analysis and optimization Repair and replacement services Emergency onsite response Emergency online response Network analysis and optimization Remote facility monitoring Compliance support services Regulatory training Safety training Consultative services for BAS regulatory compliance Specification writing SOP writing Validation Change control for system updates Factory acceptance tests (FAT) High-level commissioning GMP remediation Engineering support Chemical fume hood testing Bio-safety cabinet certification Re-entrainment testing Room pressurization testing System performance updates Field panel updates Firmware updates Software updates Datamate advanced software renewal Workstation updates

Siemens expertise is unmatched We understand your facility compliance needs BUILDING AUTOMATION HVAC CONTROLS SYSTEMS INTEGRATION FIRE ALARM AND LIFE SAFETY SECURITY CRITICAL ENVIRONMENTS INDOOR AIR QUALITY ENERGY SERVICES AND SOLUTIONS MECHANICAL SYSTEMS SERVICES Our expertise in critical manufacturing operations has been proven throughout North America. We provide a comprehensive building solutions program for design, installation, qualification and maintenance of buildings with or without cgmp requirements. We re committed to the long-term success of your compliance solutions. To this end, we have established a dedicated regulatory compliance team. These specialists oversee development of our compliance efforts and guide and support our field organization in the application of regulatory compliance solutions. Ongoing support services ensure that your system continues to meet regulatory requirements and achieves operational efficiency targets. Our compliance teams are an integrated part of the Siemens Building Technologies organization. So when you need service and support, you simply call one reliable source not two or three different vendors. Contact Siemens Building Technologies today and find out how we can help you achieve compliance at your facility. PERFORMANCE-BASED SOLUTIONS FACILITY MANAGEMENT SERVICES

Siemens Building Technologies, Inc. 1000 Deerfield Parkway Buffalo Grove, IL 60089-4513 USA Tel. (847) 215-1000 Siemens Building Technologies, Ltd. 2 Kenview Boulevard Brampton, Ontario, Canada L6T 5E4 Tel. (905) 799-9937 Siemens Building Technologies, Ltd. Hawthorne Road UK-Staines, Middlesex TW 18 3AY England Tel. 44 1784 46 16 16 Fax. 44 1784 46 46 46 www.us.sbt.siemens.com Building Technologies Helping your building work for you. APOGEE, Insight and InfoCenter Suite are registered trademarks of Siemens Building Technologies, Inc. BACnet is a trademark of the American Society of Heating, Refrigeration and Air-Conditioning Engineers (ASHRAE). LonWorks is a registered trademark of Echelon Corporation. Copyright 2004 Siemens Building Technologies, Inc. All rights reserved. Printed in the USA. 150-609P10 (01/04)