OUR SOLUTION IS YOUR SOLUTION

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1 OUR SOLUTION IS YOUR SOLUTION 1

2 CORPORATE DATA Company name: LAB.INSTRUMENTS Ltd. Registered office and headquarters: Castellana Grotte SS 172 (Putignano-Alberobello) km Secondary office: Turi (BA) Via Matteotti, Tel.: Fax: info@labinstruments.it Websites: Founded: 24 July 1984 VAT No. / Tax code: Bari CCI No of Economic Administrative Register. Bari Law Court: No and 900/84 in the company Registration List. CEO: Cosimo Mario Stefanelli MP: m.stefanelli@labinstruments.it Industry sector codes: ATECOFIN 2004 no Production of chemical products for non-industrial use. ATECO Production of pure standard products and CRM (Certified Reference Material) for environmental and food safety control. Qualifications: Provisions concerning the installation of industrial plant, as in D.M. 37/2008 of the Ministry of Economic Development, points A and E. Technical supervisor: Ing. Cesare Demarinis. Licenses: Main office on drugs (UCS), as in D.P.R. no. 309 of 09 October 1990, Ministry of Health, by D.M. no of 04 July Supervisor: Rossella Colucci. License for Hydrocarbons use (Benzene-Toluene-Xylene), law no. 786 of 30 November 1976, Ministry of Finance UTIF no of 10 November Supervisor: Dr. Cosimo Mario Stefanelli. License no for alcohol and sugary substances, as in D.P.R. no. 162 of 12 February 1965 and late adjustment, Ministry of Finance UTIF. Supervisor: Dr. Cosimo Mario Stefanelli. AVCPass System Code of A.N.A.C. (National Anti-Corruption Authority, L. 114/2014). Registrations: MIUR (Ministry of Education, Universities, and Research), registered in the ANR (National Register of Research), no UTS since Stakeholdings: Partner of D.A.Re. (Distretto Agroalimentare Regionale) Partner of Impresambiente Scrl Share capital: ,00 i.v. Net assets as in 2014 final balance: ,00 2

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4 VISION Key players in improving food safety and environmental quality MISSION Becoming the leading expert and trusted partner for both public and private entities, working in the field of scientific research Making innovative, rapid, affordable, high-quality products, which are useful in detecting residual micro-pollutants in food and in the environment Offering solutions to technical and economic problems, contributing to the certification of food quality, safety and origin Environment Innovation Experience Ethics Continuity Quality 4

5 La validità del presente certificato è subordinata a sorveglianza periodica annuale / semestrale ed al riesame completo del sistema di gestione con periodicità triennale The validity of this certificate is dependent on an annual / six monthly audit and on a complete review, every three years, of the management system L'uso e la validità del presente certificato sono soggetti al rispetto del documento RINA: Regolamento per la Certificazione di Sistemi di Gestione per la Qualità The use and validity of this certificate are subject to compliance with the RINA document : Rules for the certification of Quality Management Systems Dott. Roberto Cavanna (Managing Director) SGQ N 002 A SSI N 001 G SGA N 002 D DAP N 001 H PRD N 002 B PRS N 066 C SCR N 003 F LAB N 0832 Membro degli Accordi di Mutuo Riconoscimento EA, IAF e ILAC Signatory of EA, IAF and ILAC Mutual Recognition Agreements Via Corsica Genova Italy Per informazioni sulla validità del certificato, visitare il sito For information concerning validity of the certificate, you can visit the site Riferirsi al Manuale della Qualità per i dettagli delle esclusioni ai requisiti della norma Reference is to be made to the Quality Manual for details regarding the exemptions from the requirements of the standard CISQ è la Federazione Italiana di Organismi di Certificazione dei sistemi di gestione aziendale CISQ is the Italian Federation of management system Certification Bodies CERTIFICATIONS AND ACCREDITATIONS Lab.Instruments, following the I.L.A.C. s (International Laboratory Accreditation Cooperation) recommendations, pursues multiple accreditation, by which it is possible to guarantee the highest product and performance quality for professionals in this sector. We are the first European company to obtain EN ISO 9001:2008 and EN ISO 14001:2004 certifications, in addition to ISO/IEC 17025:2005 and ISO Guide 34:2009, having the accreditation purpose of Production of certified single component and multi-component reference materials, pesticides, metabolites, and other organic and inorganic compounds. Our certifications and accreditations contribute to provide the highest level of reliability for CRM producers, and the best quality assurance for consumers. UNI EN ISO 9001:2008 UNI EN ISO 14001:2004 ISO/IEC 17025:2005 ISO Guide 34:2009 PERRY JOHNSON LABORATORY ACCREDITATION, INC. PERRY JOHNSON LABORATORY ACCREDITATION, INC. CERTIFICATO N. 5415/01/S CERTIFICATE No. SI CERTIFICA CHE IL SISTEMA DI GESTIONE PER LA QUALITÀ DI Certificate of Accreditation Certificate of Accreditation IT IS HEREBY CERTIFIED THAT THE QUALITY MANAGEMENT SYSTEM OF LAB. INSTRUMENTS S.r.l. VIA SELVA DI FASANO, CASTELLANA GROTTE (BA) ITALIA NELLE SEGUENTI UNITÀ OPERATIVE / IN THE FOLLOWING OPERATIONAL UNITS IQNet and its partner CISQ/RINA hereby certify that the organisation Perry Johnson Laboratory Accreditation, Inc. has assessed the Laboratory of: Lab.Instruments S.r.l. S.S. 172 Putignano-Alberobello, Km. 28, Castellana Grotte (BA) Italy Perry Johnson Laboratory Accreditation, Inc. has assessed the Laboratory of: Lab.Instruments S.r.l. S.S. 172 Putignano-Alberobello, Km. 28, Castellana Grotte (BA) Italy S.S. 172 PUTIGNANO-ALBEROBELLO KM CASTELLANA GROTTE (BA) ITALIA È CONFORME ALLA NORMA / IS IN COMPLIANCE WITH THE STANDARD ISO 9001:2008 EA:19 PER I SEGUENTI CAMPI DI ATTIVITÀ / FOR THE FOLLOWING FIELD(S) OF ACTIVITIES EA:29A EA:12 PRODUZIONE DI MATERIALI DI RIFERIMENTO CERTIFICATI (CRM) E DI STANDARD CHIMICI DI RIFERIMENTO. SUPERVISIONE DELLE ATTIVITA' DI PRODUZIONE DI ARREDI TECNICI PER LABORATORIO. COMMERCIALIZZAZIONE DI STRUMENTAZIONE SCIENTIFICA, REAGENTI E MATERIALI DI CONSUMO PER LABORATORIO. PRODUCTION OF CERTIFIED REFERENCE MATERIAL (CRM) AND REFERENCE CHEMICAL STANDARDS. SUPERVISION OF MANUFACTURING ACTIVITIES OF LABORATORY TECHNICAL EQUIPMENT. TRADE OF SCIENTIFIC INSTRUMENTATION, REAGENTS AND CONSUMABLES FOR LABORATORIES Prima emissione First Issue Emissione corrente Current Issue Data scadenza Expiry Date RINA Services S.p.A. LAB. INSTRUMENTS S.r.l. VIA SELVA DI FASANO, CASTELLANA GROTTE (BA) ITALIA in the following operative units VIA SELVA DI FASANO, CASTELLANA GROTTE (BA) ITALIA S.S. 172 PUTIGNANO-ALBEROBELLO KM CASTELLANA GROTTE (BA) ITALIA for the following field of activities SUPERVISION OF MANUFACTURING ACTIVITIES FOR LABORATORY TECHNICAL EQUIPMENT. TRADE OF SCIENTIFIC INSTRUMENTATION, REAGENTS AND CONSUMABLES FOR LABORATORIES. PRODUCTION OF LABORATORY CHEMICAL STANDARDS. has implemented and maintains a Environmental Management System which fulfills the requirements of the following standard ISO 14001:2004 Registration Number: IT First Issue : Current Issue : (Hereinafter called the Organization) and hereby declares that Organization is accredited in accordance with the recognized International Standard: ISO/IEC 17025:2005 This accreditation demonstrates technical competence for a defined scope and the operation of a laboratory quality management system (as outlined by the joint ISO-ILAC-IAF Communiqué dated January 2009): Chemical Testing (As detailed in the supplement) Accreditation claims for such testing and/or calibration services shall only be made from addresses referenced within this certificate. This Accreditation is granted subject to the system rules governing the Accreditation referred to above, and the Organization hereby covenants with the Accreditation body s duty to observe and comply with the said rules. For PJLA: Initial Accreditation Date: Issue Date: Accreditation No.: Certificate No.: November 11, 2011 September 8, L Tracy Szerszen President/Operations Manager The validity of this certificate is maintained through ongoing assessments based Perry Johnson Laboratory on a continuous accreditation cycle. The validity of this certificate should be Accreditation, Inc. (PJLA) confirmed through the PJLA website: W. Big Beaver, Suite 1325 Troy, Michigan Page 1 of 2 (Hereinafter called the Organization) and hereby declares that Organization is accredited in accordance with the recognized International Standard: ISO Guide 34:2009 & the relevant requirements of ISO/IEC 17025:2005 This accreditation demonstrates technical competence for a defined scope and the operation of a laboratory quality management system (as outlined by the joint ISO-ILAC-IAF Communiqué dated January 2009): Single Component and Multi-Component Homogeneous Solutions of Organic or Inorganic Components in Solvent (As detailed in the supplement) Accreditation claims for such testing and/or calibration services shall only be made from addresses referenced within this certificate. This Accreditation is granted subject to the system rules governing the Accreditation referred to above, and the Organization hereby covenants with the Accreditation body s duty to observe and comply with the said rules. For PJLA: Initial Accreditation Date: Issue Date: Accreditation No.: Certificate No.: September 8, 2013 September 8, L Tracy Szerszen President/Operations Manager The validity of this certificate is maintained through ongoing assessments based Perry Johnson Laboratory on a continuous accreditation cycle. The validity of this certificate should be Accreditation, Inc. (PJLA) confirmed through the PJLA website: W. Big Beaver, Suite 1325 Troy, Michigan Page 1 of 2 Download certificates

6 ABOUT US Our team is made up of chemists, pharmacists, educators, and experts in instrumental chemical analysis as well as technical assistance specialists who have been working for many years in related scientific disciplines. We are a lively and dynamic team, made up of youthful, ambitious and highly motivated people. We are thinkers, travellers, health fanatics, environmentalists, and hard workers: an innovative, competitive, skilled, and efficient small company. We started in 1984 as a focused commercial business operating in the sector of scientific equipment and consumer products for chemical and clinical-chemical laboratories supply. Our partners amassed experience working in chemical and clinical-chemical labs, both at universities and hospitals; they also worked as product specialists in companies producing scientific equipment. This empowered us to offer practical support and efficient after-sales services, and garnered great customer satisfaction, trust and reliability in our work. Our core strengths boast skill-sets specific to chemical-instrumental analysis of micro pollutants, with a robust knowledge of this sector s laws and quality procedures. We also possess a keen ability to understand the latent needs of the market, and a unique versatility in adapting to and accommodating customer demand. We are the forerunners in creating Ready-to-use kits, containing multi-component mixtures of hundreds of standard pesticides: they are useful for the calibration of highly technological scientific equipment (GCMSMS, GCHRMS, LCMSMS, LCHRMS, LCFTMS, etc.). We have been the first to use, in the industrial field, a universal quantitative analytical technique, i.e., the Nuclear Magnetic Resonance (1HqNMR), in order to assign property values, metrological and NIST traceability to certified reference materials of plant protection products and other organic compounds. 6

7 1HqNMR is characterized by linearity, specificity and stability. In fact, it is considered a leading analytical method that, when compared to other techniques, does not need to follow the standard of the compound for quantification. Measurement is actually made by relating the number of protons in the analyses to those of a primary standard in a different substance. Thanks to this method, we could qualify and assign property values to hundreds of highly pure organic substances, mostly pesticides and metabolites. From these substances we produce Ready-to-use, single and multi-component solutions, including the new QuPPe-AO and QuPPE-PO mixtures, which are used for the polar pesticides analysis of food of both animal and vegetable origin. We have a wide range of QuEChERS products for the LLE extraction and clean-up (d-spe). Moreover, we are the first to make Ready-to-use products for SweEt (Swedish Ethyl) extraction. Thanks to the flexibility that distinguishes our production process, we are always ready to comply with EU regulations and the new analytical procedures, issued by the various governmental authorities, about the control of micro pollutant residuals in food. So, we are able to quickly synthesise new and customised products, according to such regulations. We have a Conference Centre where we periodically organize seminars, workshops, and training courses for the use of new scientific equipment and new analytical methodologies. PARTNERS Our team boasts strategic partnerships with other Research Corporations, Universities, CNR (National Research Bureau) as well as public and private chemical laboratories. Thanks to such professional relationships, we have been able to achieve Research Projects (PON, Cluster, etc.), scientific publications, inter-laboratory comparisons, development of multi-residual methods for the analysis of pesticides and metabolites, studies on the stability of pesticides in various alimentary origins, investigations of innovative tools to improve food safety, and more. 7

8 OUR HISTORY AND EVOLUTION Registered in the National Register of Research of MURST (Ministry of University and Scientific and Technological Research) MIUR, and recognized as Research Corporation. Creation and management of postgraduate Master Courses for young people with a degree in scientific studies. Forty internship assignments worth ,00, included in PON projects, which are financed by MURST-MIUR RESEARCH CORPORATION ESTABLISHMENT STARTING POINT R&D PRODUCTS While the 1984 Olympic Games were taking place in Los Angeles, and Carl Lewis was winning four gold medals, in the Apulian land of Trulli and Caves, Lab.Instruments Ltd. was being founded. Its members were unaware of this parallel inspiration to run beyond expectation, setting a new standard just as did the well-known champion. Starting of the R&D activities of new Certified Reference Materials (CRM). Planning and validation of multi component mixtures of pesticides for mass spectrometer calibration. Introduction of PON research projects, such as Agrihealth, worth ,00, BONES, worth ,00, S.I.Mi.S.A., worth ,00, and International Master (BiotechMAP). 8

9 Inauguration of new production labs in pollution-free areas. We are the first Italian company provided with the ATECO code. Introduction of the first kits containing hundreds of blended pesticide standards. Launch of the CRM production for the environmental and food safety control RIBBON CUTTING CEREMONY PRESS RELEASE PRESS RELEASE Perry Johnson Laboratory Accreditation Inc. 755 West Big Beaver Road Suite 1325 Troy, Michigan USA Perry Johnson Laboratory Accreditation Inc. 755 West Big Beaver Road Suite 1325 Troy, Michigan USA November 8, 2013 November 8, 2013 PJLA accredits its first Reference Material Producer in Europe PJLA accredits its first Reference Welcome Material Lab.Instruments Producer in Europe S.r.l!! Welcome Lab.Instruments S.r.l!! We are proud to announce that PJLA has accredited its first Reference Material We are proud to announce Producer that to PJLA ISO Guide has accredited 34:2009 and its first ISO/IEC Reference 17025:2005 Material in Europe. The full system Producer to ISO Guide assessment 34:2009 and was ISO/IEC conducted 17025:2005 and consisted in Europe. of the The organization s full system quality management assessment was conducted system, and technical consisted requirements of the organization s and PJLA quality technical management policies. PJLA would like to thank system, technical requirements our client, and Lab.Instruments PJLA technical policies. S.r.l. for PJLA participating would like in to the thank start up of our program. our client, Lab.Instruments Lab.Instruments S.r.l. for participating S.r.l is located in the in Castellana start up of Grotte our (BA), program. Italy and has been providing Lab.Instruments S.r.l is various located amounts in Castellana of organic Grotte standards (BA), Italy and and analytical has been standards providing for over 30 years. They various amounts of organic are standards accredited and for analytical both ISO standards Guide 34:2009 for over for 30 years. Organic They Reference Materials and are accredited for both Certified ISO Guide Reference 34:2009 Materials for Organic and to ISO/IEC Reference 17025:2005 Materials for and Chemical Testing. Certified Reference Materials and to ISO/IEC 17025:2005 for Chemical Testing. This achievement is a great opportunity for PJLA to expand into new markets. The This achievement is a need great for opportunity reference for material PJLA to producers expand into become new markets. ISO Guide The 34:2009 accredited is need for reference material becoming producers more demanding to become in ISO the Guide testing 34:2009 and calibration accredited industry. is We look forward to becoming more demanding being in one the of testing the options and calibration for reference industry. material We producers look forward to select to as an accreditation being one of the options provider. for reference The material accreditation producers program to select will assist an accreditation many of our currently accredited provider. The accreditation laboratories program that will also assist produce many reference of our standards. currently accredited They will now have the ability to laboratories that also produce become reference accredited standards. for all services They will they now provide have with the one ability accreditation to body, PJLA. become accredited for all Tracy services Szerszen, they President/Operations provide with one accreditation Manager body, PJLA. Tracy Szerszen, President/Operations Manager Internationalization of the company. Presence at International fairs (CHEM-MED Milano-Expo 2015) and at sector conferences (MS FOOD DAY 2015). Publishing of the new and catalogues. Introduction of new product lines: and GLOBAL MARKET PJLA is a MRA signatory to the Asia Pacific Laboratory Accreditation Cooperation PJLA is a MRA signatory (APLAC) to the for Asia the accreditation Pacific Laboratory of Reference Accreditation Material Cooperation Producers and a MRA signatory of (APLAC) for the accreditation the International of Reference Laboratory Material Producers Accreditation and Cooperation a MRA signatory (ILAC) of and (APLAC) for our the International Laboratory testing Accreditation and calibration Cooperation accreditation (ILAC) program. and (APLAC) for our testing and calibration accreditation program. If you would like further information regarding our Reference Material Producer If you would like further Program, information please feel regarding free to our visit our Reference website Material Producer. Program, please feel free to visit our website at CERTIFIED QUALITY Achievement of the ISO Guide Accreditations, General requirements for the competence of reference material producers and ISO/IEC 17025:2005, General requirements for the competence of testing and calibration laboratories. These are to be added to the UNI EN ISO14001:2004 and UNI EN ISO9001:2008 certifications. 9

10 MANAGEMENT TEAM Cosimo Mario Stefanelli Giovanna Mirizzi LEGAL REPRESENTATIVE & CEO PROSECUTOR & FINANCIAL MANAGER MBA - PHD BUSINESS ADMINISTRATION EXPERT QUALITY INSURER (ISO ISO GUIDE 34) EXPERT CHEMICAL ANALYSIS INSTRUMENTAL SENIOR MANAGEMENT AGE YEARS IN THE GROUP LAB POSITION Cesare De Marinis ENGINEERING 33 6 MAINTENANCE MANAGER Stefano Daprile INDUSTRIAL CHEMISTRY 64 6 PRODUCTION DEP. MANAGER Francesca Mottola CHEMICAL AND PHARMACEUTICAL TECHNOLOGIES 29 4 R&D LABORATORY MANAGER Paolo Fanizzi CHEMICAL AND PHARMACEUTICAL TECHNOLOGIES 40 5 Q.C. LABORATORY MANAGER Stella Stefanelli ECONOMICS 30 6 MARKETING MANAGER 10

11 ORGANIZATION CHART R.S.P.P. M. Stefanelli RESPONSIBLE SAFETY OF WORKERS F. Campanella LEGAL ADVISOR Studio legale Avv. Caputo FINANCIAL ADVISOR G. Vippolis QUALITY ASSURANCE CONSULTANT ISO Guide 34 - ISO ISO 80 QUALITY ASSURANCE CONSULTANT ISO IEC 17025:2005 COMPANY DOCTOR G. Marangi CONSULTANT ACCOUNTING Euroconsulting 2000 AB QUALITY ASSURANCE CONSULTANT EN ISO 9001/14001 FIRE OFFICER EMERGENCY MANAGEMENT F. Campanella CLERK FIRST AID F. Campanella G. Mirizzi CEO M. Stefanelli RESPONSIBLE MANAGEMENT OF QUALITY AND ENVIRONMENT MARKETING R&D LABORATORY SERVICING AND MAINTENANCE PRODUCTION QC LABORATORY S. Stefanelli F. Mottola C. De Marinis S. Daprile P. Fanizzi FC DC AN PF MS VI AL AD AI AA LDM FM MYS 11

12 BUSINESS AREA - STANDARDS AND CRM PRODUCTION is our product line, which includes more than 1500 single component standard solutions and CRM of pesticides and metabolites, dozens of stable and homogeneous multi-component mixtures, and some Ready-to-Use kits for the control of food safety and of environmental quality. The Ready-to-Use product range represents an alternative to the expensive as well as dangerous traditional neat standards. With them, you won t need hundreds of potentially detectable pesticides to be handled, weighted, thinned, stored, or registered. Therefore, you won t have to manage expirations and replacements, consider and compare lots, and/or qualify suppliers. works: A rapid control of the equipment tune and of the MRM transitions; To quickly update the Rt variation; To enhance selectivity and sensibility in MSMS; To improve the efficiency of measurements and reduce the frequency of calibrations; To validate the performance of the multi-residual method of analysis; To evaluate more frequently the recycling and reproducibility of the sample preparation, keeping lot to lot uniformity; To improve precision, reduce measurement error concerning in-house standard solutions, produced with volumetric procedures and the complete elimination of potential errors. Kits have been planned for a quicker and more reliable identification of over 600 analytes in the same chromatography run. Their use allows for: Significantly reduced man-hours (at least 7x) for the in-house preparation of stock calibration solutions (one for each analysis ); Cheaper purchase and disposal of dozens of litres of organic solvents (at least 30x); Risk reduction for workers health and safety concerns, preventing the handling of pesticides, which can be toxic, carcinogenic, teratogenic, and mutagenic; A lower contamination risk in work environment, chemical hoods, and laboratory glassware, caused by the use of non-diluted standard solutions. Kits contain all the plant protection products that can be referenced with the Application Notes, published by the main spectrometer producers for their customers, allowing a fast procedure. The single-component product line also includes a great amount of deuterated pesticides made by us ( ) and all those mixtures that are used for the analysis of highly polar pesticides, in products of both plant (QuPPe-PO) and animal origin (QuPPe-AO). The and products are traceable according to Primary NIST Standards and are produced in an ISO Guide 34:2009 certified company. They are also monitored in EN ISO/IEC 17025:2005 certified laboratories. 12

13 BUSINESS AREA - LLE AND CLEAN-UP d-spe EXTRACTION SYSTEMS We produce a complete QuEChERS product line for LLE extraction and clean-up (d-spe) of pesticides and mycotoxins in fruits, vegetables, cereal products, meat, juices, wine, citrus fruits, ground, etc. Such products are preparatory for a multi-residual analysis of pesticides in chromatography (GC-HPLC) and mass spectrometry (GCMSMS and LCMSMS). This method is based on a work published in 2003 by the U.S. Department of Agriculture Eastern Regional Research Center in Wyndmoor, PA (M. Anastassiades, S.J. Lehotay, D. Stajnbaher, F.J. Schenck) and replaces the old extraction methods by greatly reducing working time as well as the high costs of solvents, glassware and other special laboratory equipment. The product line has been carefully conceived to allow customers choose the products they need, according to the type of food to analyse and the typology of plant protection product to search. This product line includes more than 50 different packaging (LLE Falcon, cone-shaped tubes; self-standing 15 ml transfer tubes or sachets; 2 and 15 ml d-spe tubes) available in every formulation, in order to satisfy the customer needs and, at the same time, respecting the most widespread official methods (EN 152, AOAC , Original, etc.). The products, entirely made in Italy, according to certified procedures, are characterized by: Variety of packaging; Certified quality of raw materials; Lot to lot reproducibility; Distinctive colour code according to the matrix type; Economic packaging. In addition, the catalogue includes Mycotoxin LLE Tubes and Mycotoxin d-spe Tubes for the analysis of mycotoxins in food. Recently, we introduced our brand new products to the market: the Ready-to-Use products, based on the Swedish Ethyl Acetate Method. It is a new extraction and purification method in the multi-residual analysis of fruits, vegetables, cereals and products of animal origin. This method uses small amounts of solvents and gives extracts that are perfectly compatible with the GCMSMS and LCMSMS injection, as it inserts very low concentrations of the matrix components, like proteins and sugars. 13

14 BUSINESS AREA: CHEMICAL REACTANTS AND LABORATORY EQUIPMENT For about 30 years, we have been distributing and selling consumer products, chemical products, consumables for chromatography, and laboratory equipment to numerous national and overseas companies. Since 2006, an Italian catalogue as well as an e-commerce platform written in four languages have been available. The catalogue, now in its 4th edition, includes a selection of about 6000 items, among more than available on the online platform, that can be purchased with or without subscribing. Consumer products and basic equipment for chemical, clinical-chemical analysis, genetics, and microbiology labs are available. They are produced by over 400 notable manufacturers in the world. Our stock is in Germany, and it is managed from our Italian offices. Orders are immediately handled and prepared to be shipped within five hours after acceptance. Deliveries are made everywhere within five working days of the order being placed. Customers that have already subscribed, can purchase on the e-commerce platform, saving up to 40% and can also benefit from all the online services, such as 1) verifying in real time stock availability; 2) considering possible alternative products or the most convenient ones and on offer; 3) printing estimates, leaflets, technical features; 4) following the shipping by a tracking number, etc., and -- at the same time -- can benefit from prearranged supply terms, paying after the delivery. 14

15 BUSINESS AREA: SCIENTIFIC EQUIPMENT We sell scientific equipment for: GC, HPLC, UV-VIS, GCMS, LCMS, FTIR, and more. We exchange and rent second-hand, multi-brand equipment for chemical and clinical-chemical analysis laboratories. A wide range of second-hand, refurbished stockyard is available: GC, HPLC, EA, ICP-OES, GCMS, GCMSn, LCQqQ, FTIR, etc., mostly produced by Thermo Scientific, Thermo Finnigan, TSP, Agilent, Dani, and Nicolet. In addition to selling them, we also rent them for short and long term periods. In partnership with the most experienced supply companies, we offer any type of refurbished and budget friendly mass spectrometers: single quadrupole, triple quadrupole, ion trap, linear trap, TOF, HRMS, FTMS, connected to GC or LC and to any type of interface and sources: EI, CI+/-, ESI, APCI, APPI, etc. We supply the most competitively priced original spare parts, such as filaments, ferrules, liners, turbo molecular pumps, lamps, pistons, syringes, gaskets, filters, etc. Any kind of multiplier for all models of mass spectrometers are also available. We offer the ACB repairing service for analytical boards and circuits, with Flat Rate, Board Exchange, or Repair and Return services. We repair the main models of turbo molecular and auxiliary pumps of the biggest brands, offering a Free Rent service for the whole period of repairs.. We offer: practical support for the multi-residual analysis of micro-pollutants in environmental and food matrices, qualified technical assistance, training courses for staff, and postgraduate Master Courses. 15

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18 OUR LABS RESEARCH AND DEVELOPMENT QUALITY CONTROL METHOD DEVELOPMENT Research and development of new reference materials and systems of extraction and purification. Research on new Primary NIST Standards and matrices, stable and homogeneous, strengthened with standard pesticides. Characterization of raw materials. Qualification and certification of neats by 1HqNMR referred to Primary NIST Standards. QC on products and their packaging. Analytical method development in GCMSMS and LCMSMS, Application Note, and Validation Method to be transferred to partner labs without interruption. We have over 1000 square meters of laboratory space, in which we house a wide range of consolidated technology and scientific equipment, utilizing leading edge and stateof-the-art software. The methods we apply to our products are developed on different technological platforms, so that we can meet the diverse needs of customers. Such methods can be transferred to other labs without interruption. The labs for QC and R&D have been created thanks to a grant from the Ministry of Finance ( ,00, L. 388/2000) and the Ministry of Industry ( ,00, L. 488/92), for a total investment of ,00 to be spent on scientific equipment, such as GC, HPLC, UV, KF, EA, NIR, NMR, GCMSMS, GCHRMS, LCMSMS, LC-FTMS Orbitrap, and the like. 18

19 EQUIPMENT AVAILABLE HPLC & LC PREP Agilent 1100 Autosampler DAD (n.2) TSP AS4000 P4000 FL3000 ChromQuest TSP AS4000 P4000 DAD ChromQuest(n.2) TSP AS4000 P4000 UV3000 ChromQuest(n.2) TSP AS4000 P2000 RI Shodex (n.2) Shimadzu LC10 UV RI Gilson 232XL/321Pump Portlab LC Prep (n.2)ri Shodex LC/MSMS & LC/HRMS Agilent LC 1100 / MSD Trap XCT Ultra Thermo Surveyor MS/ TSQ Quantum Ultra Thermo LC1100/ TSQ Quantum Discovery Thermo TSP4000/LCQ DUO MSn (n.2) Thermo Accela/ Exactive* Thermo Accela / Q-Exactive* SW: excalibur,trace Finder, Mass Hunter GC Agilent6850(II)-6890 CTC (n.2) Thermo GC Ultra Triplus FID(n.3) Fisons Mega AS3000 FID/ECD (n.6) Fisons 8000 AS3000 NPD/FPD/TCD (n.3) Shimadzu GC 17A FID (n.3) GCMS & MSMS & HRMS Thermo Trace ISQ-Triplus Excalibur Agilent 7890A 5975 XL MSD Mass Hunter Thermo Fisons MD800-AI3000(n.2) Thermo Mega 2/ Trio 1000 AI3000 (n.2) Finnigan Trace 2GC/Mat95XL* Triplus Thermo Trace GC 2000/GCQn Thermo Trace GC Ultra/PolarisQ* Triplus Thermo Trace GC Ultra/TSQ GC QqQ* Triplus Thermo Trace 1300 ITQ MSn AI3000 FID NMR Bruker 400 Ultra Schield* SW ICON LIQUID HANDLING PLATFORM Packard Microprobe II EX Beckman Biomek 2000 Hamilthon Microlab 500 (n.2) OTHERS Thermo ICP-OES icap6500 Ax520 Thermo EA 1108 CHNSO SW Eager Nicolet FT-IR Magna Avatar-360/TGA(n.3) Mettler MX-XP-XPE Micro(n.3) Mettler/Kern Balance (n.11) Bosch Ampoule Filler/Sealer Bdl Cellophane Overwrapper SE550 Euralpha Isolation Safety Cabinet Trademarks: Nicolet, OMNIC, Avatar, Magna, excalibur, Surveyor, Accela, Eager, Triplus, icap, Thermo Scientific are registered trademarks of Thermo Fisher Scientific. Agilent and Mass Hunter are trademark of Agilent Technologies. Shimadzu è un marchio registrato di Shimadzu Corporation. Biomek is a trademark of Beckman Coulter. Mettler is a trademark of Mettler Toledo. Microlab and Hamilthon are trademark of Hamilthon Company. ICON, Schield are trademark of Bruker. Waters, Alleanza, Acquity sono marchi registrati di Waters Corporation; ABSciex e QTRAP sono marchi registrati di ABSciex. 19

20 WHERE WE OPERATE The market we serve is made up of: Private labs making controls on behalf of producers and exporters of fruit and vegetable products, and mass market retailers (Coop, Conad, Selex, Auchan, CRAI, Despar, Metro, Interdis, etc.); Public labs designated for quality and safety control of food (IZS, ISS, CCIAA Labs, ARPA, APAT, Lab.Dogane, MAF, etc.); Pharmaceutical Industry labs producing galenic, homeopathic and nutraceutical products using vegetal extracts; Research centres working in the food and pharmaceutical fields (CRA, CNR, University, IRCCS, CEHIAM, etc.); QC labs in food companies, controlling raw materials and finished products (Ferrero, Parmalat, Barilla, Unilever, Danone, Nestlé, Coca Cola). Our aim is to provide strategic solutions to MS manufacturers like Thermo Fisher, Agilent, ABSciex, Waters, Shimadzu, Bruker, Young Lin, Perkin Elmer, Dani, Leco, Mascom, and Hitachi, that may want to add multi-component standard mixtures to their supplying activities, in order to either perform QA/QC on mass spectrometers or satisfy those customers who want GCMS or LCMS systems, including materials and methods for the multi-residual analysis of pesticides. LABORATORIES IN ITALY LABORATORIES IN EUROPE Potential Market of food Lab Market Qualified Lab. residues Chemical laboratories of foods in Italy 212 Market Served Lab. Accredited ISO Potential Market of food Lab Market Qualified Lab. residues Chemical laboratories of foods in Europe 3265 Market Served Lab. Accredited ISO FOOD SAFETY TESTING MARKET BY FOOD TYPE MARKET PROFILE: PESTICIDE TESTING 8% Fruits and vegetables Baby food 6% 14% 32% Meat, poultry and deriv. prod. 30% Italy 4% Milk and dairy 28% Rest of Europe 8% Processed food Usa e Canada Sea food Rest of the world 10% 12% Oil, wine and drinks 12% Others 36% 20

21 CUSTOMERS PROVIDERS 21

22 THE MARKET OF OUR LABSTANDARDS AND CRM MATRIX OF THE ANNUAL GROWTH RATE OF MARKET vs RELATIVE SHARE OF EACH TYPE OF PRODUCT MATRIX OF THE SECTOR S ATTRACTIVENESS vs COMPETITIVENESS OF EACH TYPE OF PRODUCT Matrix type BCG Neat 5 Matrice McKinsly Neat Single Solution Single Solution Mix Solution Mix Solution Growth 10% CRM Kits Attractiveness CRM Kits 1 Market share The market share is the ratio between the revenue of a typology of product and the total revenue. 0 Competitiveness The relation between the level of the sector s attractiveness and the competitiveness of each typology of product. 5 POSITIONING Q 10 LBS Q+S 10 LBS 7,5 LBS SGM PHN RST ABS LGC SGM ODS WTR 7,5 LBS ABS PHN SGM LGC SGM ODS WTR ULT WTR ABS RST WTR ABS 5 SCH ODS PHN RST 5 SCH ODS ULT PHN RST 2,5 LGC ULT 2,5 LGC ULT SCH SCH 0 2,5 5 7,5 10 P 0 2,5 5 7,5 10 P+CF Q = Product quality P = Product price Q+S = Product quality and services P+CF = Price + Supply Conditions Positioning considers the main competitors, according to: intrinsic product quality, certifications and validations, availability of innovative products (, Ready to Use kits). positioning considers the quality of the after-sales service and the applied supply conditions. 22

23 THE MARKET OF OUR EXTRACTION SYSTEMS (LLE) AND CLEAN-UP (d-spe) MATRIX OF THE ANNUAL MARKET GROWTH RATE vs RELATIVE SHARE OF EACH TYPE OF PRODUCT MATRIX OF THE SECTOR S ATTRACTIVENESS vs COMPETITIVENESS OF EACH TYPE OF PRODUCT Matrice tipo BCG 5 Matrice McKinsly Micotoxin-LLE Micotoxin-LLE Growth 10% Attractiveness 1 Market share The market share is given by the ratio between the revenue of a certain typology of product and the total revenue. 0 Competitiveness The relation between the sector s level of attractiveness and the competitiveness of each, or Mycotoxin product lines. 5 POSITIONING Q 10 7,5 LBS RST THR SGM WTR AGT ULT LBS SGM AVN WTR AGT Q+S 10 7,5 LBS RST SGM WTR AGT ULT LBS SGM AVN WTR AGT 5 MKN MKN 5 THR MKN 2,5 AVN SCH RST THR ULT 2,5 AVN SCH MKN RST THR ULT SCH SCH 0 2,5 5 7,5 10 P 0 2,5 5 7,5 10 P+CF Considering the main competitors, according to: intrinsic product quality, certifications and validations, availability of innovative products ( ). positioning considering the quality of the after-sales service and the applied supply conditions. 23

24 OVERVIEW K TOTAL INCOME +17,9% vs K TOTAL LIABILITIES -2,2% vs K PT (CAPITAL AND RESERVES) +1,63% vs K CASH FLOW +7,4% vs ,7 K OPERATING NET PROFITS (AFTER TAXES) +182% vs K PFN (NET FINANCIAL POSITION) -9,64% vs

25 vs 5 vs vs 2013 PRODUCTS PRODUCTION LINES EFFECTIVE WORK FORCE (employees+members+contractors) 7270 FIXED TANGIBLE ASSETS 5158 K K NET TANGIBLE ASSETS NW 1 TL 2 % = 40,4 LTD 4 = OMG 3 TD 5 0,75 = FC 6 6,03 GOM 3 SALES VOL. % = 9,3 PFN EBITDA = PFN 10,3 = NW 1 0,83 1 Net Worth 2 Total Liabilities 3 Gross Operating Margin 4 Long-term Debt 5 Total debt 6 Financial charges 25

26 DEVELOPMENT STRATEGY As structural costs inevitably increase, eroding the operating margins, and commercial intermediaries are usually threatened by competitiveness, we decided to take advantage of our long-standing experience and turned our commercial company into a chemical factory, able to produce technologically advanced products that are also innovative, non-fungible, and competitive. This has led to important investments on tangible assets, such as labs with advanced scientific equipment, special machinery systems, and also stafftraining and qualification enhancement. Our development strategy aims at combining the growth deriving from the production and sale of the and products with the commercialization of chemical products, consumables and laboratory equipment that are in the catalogue and on the e-commerce platform. Great importance is currently being given to the business area concerning the exclusive national sale of scientific equipment: HPLC, GC, GCMS, LCMS, FT-IR, AA, UV/VIS, and the rental of refurbished, high resolution mass spectrometers. Our goal is to offer holistic solutions (equipment, methods, extraction system, calibration standards, consumables, ASP, technical assistance, staff training, financial proposals, etc.), where the whole is greater than the sum of its parts. NATIONAL SALES NETWORK Inclusion, in chemical labs, of skilled salespersons, able to carry out multi-residual analysis on food. GLOBAL PRESENCE Development of a global distribution network, and growth of our international market presence, through the establishment of partnerships with strategic foreign suppliers. TECHNOLOGY UPDATE Introduction of the new refrigerated R3TC (Real Time Track Temperature Control) transport system, in order to safely supply over long distances, especially to non-european markets. NEW PRODUCT LINES ACCREDITATIONS DIRECT MARKETING DEVELOPMENT Launch of new standards, new CRMS, sale and rental of new and refurbished scientific equipment. Good Manufacturing Practices (GMP) accreditation for the pharmaceutical production sector. Increase in direct communication and web marketing as a support system for the sales network and customer information. 26

27 GROWTH FORECAST When, in 2014, the and lines were introduced in the product portfolio, there was an immediate increase in revenue and income. Forecast is optimistic also for the commercialized products and the scientific equipment rental activity. REVENUE AND PROVISIONAL REVENUE FOR BUSINESS AREA AND PROVISIONAL , % ,00 90 % 80 % ,00 70 % 60 % ,00 50 % ,00 40 % 30 % ,00 20 % 10 % anni 0 % anni SPLIT 2014 REVENUES FOR AREA SPLIT 2018 REVENUES (PROVISIONAL) FOR AREA 7 % 4 % 9 % 2 % 78 % 20 % 24 % 4 % 37 % 15 % & & CRM & Laboratory Equipment & E-Commerce Sale and rental refurbished and Others Others 27

28 SALES NETWORK In order to optimise our engagement of the national and international qualified market, a regional sales network has been created. It is made up of skilled salespersons, operating in chemical labs where multi-residual analysis of pesticides are carried out. Agency and Storage in Turin (ASP) Piedmont - Valle d Aosta Agency and Storage in Milan (STR) Lombardy Agency and Storage in Padua (MP) Veneto - Friuli Trentino Alto Adige Reykjavik Milan Padova Turin Agency in Florence (AN) Tuscany - Liguria Florence Bologna Agency in Bologna (RM) Emilia Romagna Ancona Agency in Ancona (FL) Abruzzo - Molise Umbria - Marche Dublin Oslo Helsinki Stockholm Tallinn Riga Copenhagen Minsk London Amsterdam Bremen Varsavia Berlin Bruxelle Kiev Paris Prague Moscow Cagliari Agency in Rome (RT) Lazio Rome Naples Agency in Naples (AF) Campania Bari Agency and Storage in Bari (LBS) Puglia - Basilicata Lisbon Madrid Bern Monaco San Marino Rome Vienna Bratislava Budapest Zagreb Belgrade Bucharest Sarajevo Sofia Tirana Athens Ankara Agency and Storage in Cagliari (GA) Sardinia Agency and Storage in Messina (LBS) Sicily Messina Cosenza Agency and Storage in Cosenza (RS) Calabria Valletta Agency Agenzia e Storage Distributors Distributors (hereafter) 28

29 ONLINE SERVICES Considering the widespread use of the Internet, even in our sector, we have developed Direct Marketing Platforms as a support for e-commerce customers and overall sales network. APPLICATION NOTE VALIDATION METHOD VIDEO TUTORIAL QUICK SEARCH OF PRODUCTS E-COMMERCE FOR ORDERS, ESTIMATES, CONTROL SHIPMENTS ON DEMAND WEBINARS & WEBINARS LIBRARY CERTIFICATES, MSDS, DOCUMENTATION AND PRODUCT INFORMATION COMPANY PRODUCTS NEWS CONTACT #BetterCallLabInstruments LABSTANDARD QUE-LAB CATALOGUE ONLINE LAB INSTRUMENTS SOCIAL NETWORK On our website, you will find many online resources. Lab Instruments is present on the major social networking sites and on the new website, which is rich in pictures, textual, and multimedia content. In the download area you can download the PDF catalogue of the available promotional products as well. 29

30 30

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32 alessandronitti graphicdesigner Download certificates Accreditations and Certifications ISO Guide 34:2009 ISO/IEC 17025:2005 UNI EN ISO 14001:2004 UNI EN ISO 9001:2008 Produced by: LAB. INSTRUMENTS S.r.l. - High Pure Standards & Chemicals Division Tel Fax: SS 172 (Putignano-Alberobello) km Castellana Grotte (BA) Site: info@labinstruments.it,,, and are a trademark of Lab.Instruments srl (Italy). All rights reserved. Specifications, term and pricing are subject to change. Not all products is available in all countries. Please consult your local rapresentative to details. CP 02 E 10/15 32

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