Gold Nanoparticles & Custom Conjugation

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1 Gold Nanoparticles & Custom Conjugation

2 p 02 Our unique gold has been used for over 20 years ensuring you get superior quality and performance.

3 Gold nanoparticles for lateral flow development and maufacture BBI Solutions unique gold nanoparticles have been used for over 20 years. Due to their superior quality and performance, they feature in over 400 million tests in the global market place per year, many of which have FDA cleared status. Along with our world renowned gold, we offer gold conjugates which are designed to help our customers develop and manufacture their diagnostic tests at a rapid and economical rate, making BBI Solutions your partner of choice for your lateral flow reagents. BBI s gold nanoparticles give optimum performance, with superior stability, sensitivity and binding properties. Our manufacturing facilities and processes allow us to offer batch sizes of up to 350 litres, all with a shelf life of 12 months. There is a diverse range of particle sizes available from 2nm to 250nm supplied ready for conjugation, to save you time and money. As the market has grown to expect higher levels of sensitivity, our gold has increasingly become regarded as an extremely reliable raw material to provide an accurate visual signal in lateral flow tests. + High stability ensures a manufacturing regime that saves you time and needless waste. + A low coefficient of variation, uniform shape and standardised size promoting even antibody binding, reduces the risk of clutering and collapsed material. + Rigorous quality control prior to batch release ensures the best quality gold and gold conjugate is available providing peace of mind. High quality, mono-dispersed gold from BBI Solutions Aggregated, odd shaped competitor gold p 03

4 p 04

5 Highly Concentrated Gold Nanoparticles BBI s concentrated gold nanoparticles can be used to simplify the conjugation procedure by eliminating the goldconcentration centrifugation step. This product is available off-the-shelf for optical densities ranging from 5 to 100 nm. If you need something specific, then we can manufacture a personalised product for you. + Reduced Labour Costs The concentration process can be labour intensive. By using high OD gold nanoparticles from BBI, you can reduce laboratory and production costs, leading to increased profitability. + Reduced Risk The potential for aggregates is greatly minimised as the concentration process can be damaging to the nanoparticles due to the centrifugation steps. Let BBI s take responsibility for this and receive a product of guaranteed quality, at your required concentration. Catalogue Gold Conjugates Alongside our leading gold nanoparticles, BBI offers a number of catalogue gold conjugates, designed to help our customers develop and manufacture their diagnostic tests at a rapid and economical rate. Our product range includes antibiotin, anti-human, anti-species and disease state catalogue gold conjugates. These are manufactured using BBI s unique gold nanoparticles at our site in the UK. + Anti-biotin conjugates + Anti-human conjugates + Anti-species conjugates + Control lines + Disease state conjugates + Fertility conjugates + Negative control conjugates + Anti-6 his tag conjugates p 05

6 Quality Assured All of BBI Solutions development and manufacturing processes are performed within the framework of the ISO 9001 or ISO quality management systems. Our aim is to maintain the highest standards of quality as well as exceptional levels of service. We have FDA and ANVISA registered manufacturing sites and we are confident that the procedures that we have in place allow us to exceed our customer s expectations. p 06

7 Custom Conjugation Service for Fully Optimised Antibody-Gold Conjugates If you are looking for a more specialised conjugate, BBI can take your antibody of choice and using our long established, proven processes, optimise your conjugate, and then put a commercial supply plan in place. BBI custom conjugation service allows the bespoke production of high quality conjugates optimised to meet your sensitivity specifications. Our scientists work to provide stable, reproducible conjugates efficiently and within a minimal timescale, making this the best value feasibility service available. Once you have selected the best antibodies, intensive optimisation is carried out to ensure first class conjugation: + Optimisation of sensitivity and stability + Set up for regular production + Long term stability analysis We supply you with a robust conjugate to meet your individual requirements: + Batch sizes up to 24L (@ OD10) + provided in various proprietary buffers + Regular supply to meet customer demand p 07

8 Get in touch to find out more about how BBI Solutions can help you USA: Intl: +44 (0)

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