GI CP (Imclone) A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer Open to accrual NCT
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1 Breast ALTENS(Hot Flash Study) A Phase II Study of Acupuncture-like trancutaneous electrical nerve stimulation in the management of vasomotor symptoms induced by breast cancer treatments. Breast Cardiac Biomarker (Cabot) Determining the Cardiac Biomarker Profile in Breast Cancer Patients Receiving Adjuvant Trastuzumab Therapy Breast IND.197 A Phase II Study of Foretinib in Patients With Estrogen Receptor (ER), Progesterone Receptor (PR), and Human Epidermal Growth Factor Receptor 2 (HER2) Negative, Recurrent/Metastatic Breast Cancer Breast LEGACY Establishment of a cohort of girls in breast cancer families The Ontario LEGACY Pilot Breast MA.32 A Phase III Randomized Trial of Metformin Versus Placebo on Recurrence and Survival in Early Stage Breast Cancer Breast MA.33 A Randomised Phase III Study Of Radiation Doses And Fractionation Schedules For Ductal Carcinoma In Situ (Dcis) Of The Breast Breast MAC.15 (S1007) A Phase III, Randomized Clinical Trial of Standard Adjuvant Endocrine Therapy +/- Chemotherapy in Patients With 1-3 Positive Nodes, Hormone Receptor-Positive and Her2-Negative Breast Cancer With Recurrence Score (RS) of 25 or Less Breast OCOG-2010-IMPACT A Pilot Study of Blood Oxygen Level Dependent Magnetic Resonance Imaging (BOLD MRI) and Fluorothymidine Positron Emission Tomography (FLT PET) in Patients With Locally Advanced Breast Cancer Undergoing Neoadjuvant Chemotherapy NCT NCT NCT NCT NCT Breast Once-A-Day Partial Once-A-Day Partial Breast Irradiation(OPAR): a feasibility study Breast Irradiation(OPAR) Breast ONCOTYPEDX A Prospective Cohort Study to Evaluate the Oncotype DX Test in NCT Early Stage Breast Cancer GI CP (Imclone) A Study of IMC-1121B or IMC-18F1 in Colorectal Cancer NCT
2 GI CRC.6 Oxaliplatin, Leucovorin Calcium, and Fluorouracil With or Without NCT Celecoxib in Treating Patients With Stage III Colon Cancer Previously Treated With Surgery GI JX594-CRC019 A Phase 1/2a Dose-escalation Study of JX-594 (Thymidine Kinase- Deactivated Vaccinia Virus plus GM-CSF) Administered by Multiple Intravenous (IV) Infusions Followed by Intratumoral (IT) Boosts Alone and in Combination with Irinotecan in Patients with Metastatic, Refractory Colorectal Carcinoma. NCT GI OXALI_L_04918(PANCRE Randomized Study With Oxaliplatin in 2nd Line Pancreatic Cancer OX) GU\RENAL AV A Rollover Protocol to Allow Continued Access to Tivozanib (AV- 951) for Subjects Enrolled in Other Tivozanib Protocols GU\RENAL IMRT_ISD_JARES Randomized Study of Quality of Life in Patients with High-Risk Prostate Cancer Undergoing Radiotherapy: Role of Pelvic Nodal IMRT GU\RENAL IND.205 A Phase II Study of PX-866 in Patients With Recurrent or Metastatic Castration Resistant Prostate Cancer GU\RENAL MUC1 A Phase I/II Study Evaluating the Safety and Efficacy of Vaccination With Autologous Dendritic Cells Loaded With Tn-MUC1 Peptide in Patients With Non-Metastatic Androgen Independent Prostatic Adenocarcinoma. GU\RENAL OGX A Randomized Phase 3 Study Comparing Standard First-Line Docetaxel/Prednisone to Docetaxel/Prednisone in Combination with Custirsen (OGX-011) in Men with Metastatic Castrate Resistant Prostate Cancer GU\RENAL OGX A Randomized, Double-blind Phase 2 Study Comparing Gemcitabine and Cisplatin in Combination with OGX-427 or Placebo in Patients with Advanced Transitional Cell Carcinoma NCT NCT NCT NCT NCT NCT GU\RENAL OZM-042 A Phase II, Multi-Centre, Study of the Efficacy and Safety of Sunitinib Given on an Individualized Schedule as First-Line Therapy for Metastatic Renal Cell Cancer. NCT
3 GU\RENAL PR.01 A Randomized Phase II Study of OGX-427 (a Second-Generation Antisense Oligonucleotide to Heat Shock Protein-27) in Patients With Castration Resistant Prostate Cancer Who Have Not Previously Received Chemotherapy for Metastatic Disease NCT GU\RENAL PR.13 RADICALS - Radiotherapy and Androgen Deprivation In NCT Combination After Local Surgery GU\RENAL RTOG 0534 A Phase III Trial of Short Term Androgen Deprivation With Pelvic NCT Lymph Node or Prostate Bed Only Radiotherapy (SPPORT) in Prostate Cancer Patients With a Rising PSA After Radical Prostatectomy GU\RENAL RTOG 0938 A Randomized Phase II Trial of Hypofractionated Radiotherapy for NCT Favorable Risk Prostate Cancer GU\RENAL VEG113387(PROTECT) A Randomized, Double-blind, Placebo-controlled Phase III Study to NCT Evaluate the Efficacy and Safety of Pazopanib as Adjuvant Therapy for Subjects With Localized or Locally Advanced RCC Following Nephrectomy GYNE CBKM120C2201 A Phase II, Single-arm Study of Orally Administered BKM120 as On hold NCT Second-line Therapy in Patients With Advanced Endometrial Carcinoma GYNE MK A Randomized, Phase II Study Evaluating MK-1775 in Combination NCT With Paclitaxel and Carboplatin Versus Paclitaxel and Carboplatin Alone in Adult Patients With Platinum Sensitive p53 Mutant Ovarian Cancer GYNE MM A Phase II Randomized Open Label Study of MM-121 in combination with Paclitaxel versus Paclitaxel alone in patients with Platinum Resistant/ Refractory Advanced Ovarian Cancers NCT GYNE PET LACE Impact of Positron Emission Tomography (PET) Imaging in Women With Locally Advanced Cervical Cancer (PET LACE Trial) NCT
4 Head&Neck REO 018 Randomized, Double-blind, Multicenter Two-Stage Adaptive Phase 3 Study of Intravenous Administration of REOLYSIN (Reovirus Type 3 Dearing) in Combination With Paclitaxel and Carboplatin Versus the Chemotherapy Alone in Patients With Metastatic or Recurrent Squamous Cell Carcinoma of the Head and Neck Who Have Progressed on or After Prior Platinum-Based Chemotherapy NCT Head&Neck RTOG 0631 Phase II/III Study of Image-Guided Radiosurgery/SBRT for Localized NCT Spine Metastasis Head&Neck T2 Larynx Phase I Study of Tolerance of Localized Glottic (T2 N0) Cancer treated with Dose Escalated Intensity Modulated Radiation Therapy Hematology BEND-ACT An Open-Label Expanded Access Trial for Bendamustine HCl in NCT Patients with Indolent Non-Hodgkin s Lymphoma that has Progressed during or following Treatment with a Rituximab Regimen or Previously Untreated Chronic Lymphocytic Leukemia (BEND-ACT) Hematology CA Dasatinib (BMS ) Combined With SMO Inhibitor (BMS- NCT ; XL139) in CML With Resistance or Suboptimal Response to a Prior TKI Hematology CAM0104(Accapella) Alemtuzumab and CHOP Chemotherapy for Aggressive Histological NCT Peripheral T-Cell Lymphomas: A Multi-centre Phase I and II Study Hematology CINC424B2301(RESPON SE) Randomized, open label, multicenter phase III study of Efficacy and Safety in POlycythemia vera subjects who are resistant to or intolerant of hydroxyurea: JAK inhibitor INC424 tablets versus best available care (The RESPONSE Trial) NCT Hematology PHL-074 A Phase I/II study of azacitidine combined with mitoxantrone and etoposide (ANOVE) chemotherapy for patients age > 60 with poor prognosis acute myeloid leukemia (AML). NCT
5 Lung BR.26 A Double Blind Placebo Controlled Randomized Trial of PF-804 in NCT Patients With Incurable Stage IIIB/IV Non-Small Cell Lung Cancer After Failure of Standard Therapy for Advanced or Metastatic Disease Lung CA A Multi-arm Phase I study of BMS in combination with NCT Gemcitabine/Cisplatin, Pemetrexed/Cisplatin, or Carboplatin/Paclitaxel in subjects with Chemotherapy-Naive Stage IIIB/IV Nonsmall Cell Lung Cancer (NSCLC) Lung CONVERT/BR.28 A 2-arm randomised controlled trial of concurrent chemoradiotherapy comparing twice-daily and once-daily radiotherapy schedules in patients with limited stage small cell lung cancer (SCLC) and good performance status Lung EMR An open-label trial to collect long-term data on subjects following NCT particpation in previous EMD (L-BLP25 or BLP25 liposome vaccine) clinical trials. Lung IMGN A Phase 1/2 Study to Assess the Safety and Efficacy of NCT Lorvotuzumab Mertansine (IMGN901) in Combination with Carboplatin/Etoposide in Patients with Advanced Solid Tumors including Extensive Stage Small Cell Lung Cancer Lung OCOG-2011-BRACHY A Phase III, Multi-centre, Randomized Trial to Evaluate the NCT Symptomatic and Quality of Life Improvements in Lung Cancer Patients Receiving External Beam Radiation With or Without High Dose Rate Intraluminal Brachytherapy Lung OSI A Randomized, Double-Blind, Phase 2 Study of Erlotinib (Tarceva ) in Combination With OSI-906 or Placebo in Chemonaive Patients With Advanced NSCLC With Activating Mutations of the Epidermal Growth Factor Receptor (EGFR) Gene NCT Lung STA A Randomized, Phase IIB/III Study of Ganetespib (STA-9090) in Combination With Docetaxel Versus Docetaxel Alone in Subjects With Stage IIIb or IV Non-Small-Cell Lung Cancer NCT Lung STA A Study of Ganetespib in Subjects With ALK-Positive Non-Small-Cell Lung Cancer (NSCLC) (CHIARA) NCT
6 Lung TIDAL A Randomized Phase II Crossover Study of Tiotropium For Dyspnea NCT in Advanced Non-Small Cell Lung Cancer Melanoma IND.202 A Randomized Phase II Study of Interleukin-21 (ril-21) Versus NCT Dacarbazine (DTIC) in Patients With Metastatic or Recurrent Melanoma Melanoma MEK A Phase III, randomized, double-blinded study comparing the combination of the BRAF inhibitor, dabrafenib and the MEK inhibitor, trametinib to dabrafenib and placebo as first-line therapy in subjects with unresectable (Stage IIIc) or metastatic (Stage IV) BRAF V600E/K mutation-positive cutaneous melanoma. NCT Melanoma Melanoma-Specific Immunity Analysis of Melanoma-Specific Immunity Neuro CDX (ACT IV) An International, Randomized, Double-Blind, Controlled Study of Rindopepimut/GM-CSF with Adjuvant Temozolomide in Patients with Newly Diagnosed, Surgically Resected, EGFRvIII-positive Glioblastoma (The ACT IV Study) NCT Neuro CE.6 A Randomized Phase III Study of Temozolomide and Short-Course NCT Radiation Versus Short-Course Radiation Alone In The Treatment of Newly Diagnosed Glioblastoma Multiforme in Elderly Patients Neuro CEC.3/N107C A Phase III Trial of Post-Surgical Stereotactic Radiosurgery (SRS) Compared with Whole Brain Radiotherapy (WBRT) for Resected Metastatic Brain Disease Neuro CIPN (neuropathy) A Phase I/II study to examine the accuracy of spinal cord functional MRI scan in evaluating chemotherapy induced peripheral neuropathy and the efficacy of acupuncture and acupuncture-like transcutaneous nerve stimulator in treating this condition Neuro JNG-001(TRICK) A Randomized Trial of Robotic Compared to Fixed Gantry Radiosurgery for Brain Metastases. Neuro N0574(RTOG 0671) A Phase III Randomized Trial of the Role of Whole Brain Radiation Therapy in Addition to Radiosurgery in Patients With One to Three Cerebral Metastases NCT NCT NCT
7 Neuro RTOG 0539 A Phase II Trial of Observation for Low-Risk Meningiomas and of Radiotherapy for Intermediate- and High-Risk Meningiomas NCT Neuro RTOG 0933 A phase 2 trial of hippocampal avoidance during whole brain radiotherapy for brain metastases Other IND.206 A Phase II Study of Sunitinib or Temsirolimus in Patients With Advanced Rare Tumours Phase I CBKM120E2101 A Phase I, two-stage, multi-center, open-label dose escalation study of BKM120 in combination with adjuvant temozolomide and with concomitant radiation therapy and temozolomide in patients with newly diagnosed glioblastoma Phase I NP27872 A multi-center, open-label, first-in-human, phase I dose-escalation study of single agent RO , a small molecule MDM2 antagonist, administered orally in patients with advanced malignancies, except leukemia Phase I PJC-008 A Phase I Trial of AMG 386 and Temsirolimus in Advanced Solid Tumors with an Expansion Cohort in Uterine Cancer, Renal Cell Carcinoma and Carcinoid Tumor Phase I SOR-C13 01 A Phase I, Open-Label, Dose Escalation Study To Assess Safety and Tolerability of Sor-C13 in Subjects with Advanced Solid Tumors Commonly Known to Express The Trpv6 Ion Channel Phase I TGWS-001 Feasibility Clinical Study of Targeted and Genome-Wide Sequencing NCT NCT NCT NCT NCT NCT NCT * You can search the general information of the trials by using the clinicaltrial.gov identifier provider here. Updated by September 1, 2012
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