How To Treat An Autoimmune Disease

Transcription

1 Programma di ricerca Regione-Università Bando Giovani Ricercatori Alessandro Liberati 2013 NOT ELIGIBLE FOR FUNDING CCOODDIICCEE CCOOGGNNOOMEE NNOOMEE EENNTTEE TTIITTOOLLOO AARREEAA TTEEMAATTIICCAA BIAGINI Elena SEARCH FOR KNOWN AND NOVEL DISEASE GENES BY WHOLE EXOME SEQUENCING IN PATIENTS WITH COMPLEX PHENOTYPE CARDIOMYOPATHIES BOLZONI Marina Parma CHARACTERIZATION AND ENRICHMENT OF BONE MARROW CD271+ MESENCHYMAL STEM CELLS: CLINICAL EFFECT OF THE USE OF COMBINED MESENCHYMAL STEM CELLS BASED TECHNIQUE FOR BONE REGENERATION IN CHILDREN. Regenerative medicine & transplantation BONONI Ilario Ferrara NOTCH GENES AND SIMIAN VIRUS 40 INFECTION IN BREAST CANCERS

2 CADOSSI Matteo ADIPOSE DERIVED VERSUS BONE MARROW DERIVED MESENCHYMAL CELLS FOR OSTEOCHONDRAL LESIONS OF THE ANKLE JOINT: AN IN VIVO ANIMAL EVALUATION AND A RANDOMIZED CONTROLLED TRIAL IN HUMANS. Regenerative medicine & transplantation CLISSA Cristina AZACITIDINE AND LENALIDOMIDE COMBINATION THERAPY FOR TREATMENT OF MYELODYSPLASTIC SYNDROMES: EFFICACY AND RELATIONSHIP WITH MOLECULAR RESPONSE CRITELLI Rosina Maria TGFBETA1 AS A DRIVER OF PRO- ANGIOGENIC PHENOTYPE IN HEPATOCELLULAR CARCINOMA: A PROMISING TARGET FOR THERAPY DABABNEH Hussam PREDICTIVE BIOMARKERS OF RESPONSE TO SECOND GENERATION ANTI-ANDROGENS IN CASTRATION RESISTANT PROSTATE CANCER (CRPC) DALLA PALMA Anna Benedetta Parma OMICS PROFILES OF THE BONE MARROW MICROENVIRONMENT CELLS IN RELATIONSHIP WITH CLINICAL FEATURES OF MULTIPLE MYELOMA PATIENTS: IDENTIFICATION OF NEW BIOMARKERS 2

3 DE TROIA Alessandro Ferrara AXILLARY REVERSE MAPPING (ARM).TRY TO IDENTIFY AND SPARE LYMPHATIC PATHWAYS IN BREAST CANCER SURGERY TO PREVENT BREAST CANCER RELATED LYMPHEDEMA (BCRL) Rehabilitation DI GREGORI Valentina THE PATIENT PROFILE FOR ADVERSE EVENTS DERIVED FROM ECTODERMA AFTER SINGLE OR COMBINED VACCINATION ADMINISTRATION. Viral and autoimmune pathologies DI MARTINO Alessandro PREDICTIVE MODEL FOR BIOMIMETIC SCAFFOLDS IN KNEE SURGERY: FROM IN VITRO EXPERIMENTAL TO COMPUTATIONAL APPROACH FOR MULTILAYERED SCAFFOLDS MECHANICAL CHARACTERIZATION. Advanced diagnostics GODINO Lea IMPACT OF GENETIC COUNSELLING ON RISK PERCEPTION AND SURVEILLANCE OF WOMEN WITH FAMILY HISTORY OF BREAST CANCER HUBER Alexa PSYCHOLOGICAL AND BRAIN FACTORS OF PAIN AND ITS COGNITIVE MODULATION IN FIBROMYALGIA SYNDROME Neuroscience 3

4 MAGNANI Giulia MECHANISMS OF TUMORIGENESIS IN INDIVIDUALS WITH COLORECTAL CANCER (CRC) BEFORE AGE OF 40 YEARS AND IN PATIENTS WITH FEATURES OF LYNCH SYNDROME WITHOUT DNA MISMATCH REPAIR GENES INVOLVEMENT MANCO Gianrocco EVALUATION OF THE CHEMOPREVENTIVE EFFECTS OF THE ASSOCIATION BETWEEN MESALAZINE AND VITAMIN D3 AND IDENTIFICATION OF CIRCULATING MIRNAS FOR THE DIAGNOSIS OF THE EARLY STAGES OF COLON CARCINOGENESIS MANGIERI Domenica Parma PRECLINICAL RE-QUALIFICATION OF NATALIZUMAB FOR BILATERAL IMMUNOTHERAPEUTIC TARGETING OF PERICYTE AND TUMOUR ALPHA4 INTEGRINS IN MELANOMA METASTASIS: IN VITRO AND IN VIVO VALIDATION MAZZANI Roberta Parma EFFECTIVENESS OF VISCOELASTIC-TEST TO IDENTIFY THE TIMING OF THROMBOPROPHYLAXIS IN TRAUMA PATIENTS: A PROSPECTIVE RANDOMIZED TRIAL 4

5 MOSCATIELLO Simona WEB-BASED EDUCATIONAL PROGRAM TO HEALTHIER LIFESTYLES IN SUBJECTS WITH OR AT HIGH RISK FOR METABOLIC SYNDROME PALANDRI Francesca THE ROLE OF JAK INHIBITORS ON THE INFLAMMATORY MICROENVIRONMENT OF MYELOFIBROSIS: AN IN VITRO AND EX VIVO BIOLOGICL AND FUNCTIONAL STUDY PALINI Gian Marco Ferrara EARLY DIAGNOSIS OF PANCREATIC CANCER IN SELECTED HIGH-RISK POPULATION DIABETES, GENETIC PREDISPOSITION, INTRADUCTAL PAPILLARY MUCINOUS NEOPLASM AND MUCNOS NEOPLASM OF THE PANCREAS PAPAYANNIDIS Cristina SELECTIVE INHIBITION OF FLT3+ LEUKEMIC STEM CELLS BY USE OF THE FLT3 INHIBITOR PONATINIB RICCARDI Federica Parma MOLECULAR SCREENING OF NEW CANDIDATE GENES INVOLVED IN INHIBITOR DEVELOPMENT IN SEVERE HAEMOPHILIA PATIENTS: LOOKING AT A PERSONALIZED THERAPEUTIC APPROACH Advanced diagnostics 5

6 RICCARDI Silvia Parma TERRITORIAL MANAGEMENT OF CONTINUOUS POSITIVE AIR PRESSURE (CPAP) TREATMENT IN PATIENTS WITH OBSTRUCTIVE SLEEP APNEA: AN EPIDEMIOLOGICAL STUDY Neuroscience RINALDI Elisa Rebecca ACTIVATION OF THE RENIN ANGIOTENSIN SYSTEM IN A POPULATION OF PATIENTS WITH RHEUMATOID ARTHRITIS AND LOW SEVERITY OF COMORBIDITY AND DMARDS THERAPY AND/OR BIOLOGIC DRUGS SALVI Giorgio REALIZATION OF BONE GRAFTS BY 3D PRINTING POSITIONING OF ALGINATE DROPLETS CARRING MSC, MICROSPHERE AND ECM COMPONENTS INTO A CUSTOM MADE BIOREACTOR Regenerative medicine & transplantation SERRELLI Giulio Parma IMAGING THE FUNCTIONAL NEUROANATOMY OF PARKINSON DISEASE: FOCUS ON SUBTYPES AND IMPLICATIONS FOR TREATMENT ASSESSED BY PET AND MRI TRACTOGRAPHY IMAGING. A CASE-CONTROL STUDY. Advanced diagnostics 6

7 SIMONETTI Giulia COGNITIVE DYSFUNCTIONS AND CHRONIC HEPATITIS C: A PROSPECTIVE STUDY TO EVALUATE THE IMPACT OF ANTIVIRAL TREATMENT ON THE NEUROPSYCHOLOGICAL STATUS OF PATIENTS Viral and autoimmune pathologies TALARICO Anna Ferrara PHARMACOKINETICS OF CANCER CHEMOTERAPEUTIC AGENTS: EVALUATION OF THE DISTRIBUTION OF THE UNCHANGED ACTIVE SUBSTANCE AND RELAVANT METABOLITES FOR THE OPTIMIZATION OF THE THERAPY TAMBURINI Elisa Parma THE CHROMATIN-REMODELING PROTEINS ATRX/DAXX AS EPIGENETIC DRIVERS OF CANCER: A RETROSPECTIVE OBSERVATIONAL STUDY IN NEUROENDOCRINE TUMORS TAVANTI Elisa IDENTIFICATION OF OSTEOSARCOMA DRIVING PROTEIN KINASES AND KINASE INHIBITORS TO DEFINE NOVEL TREATMENT STRATEGIES VITALE Giovanni CHRONIC HEPATITIS C, MENTAL HEALTH, QUALITY OF LIFE AND ADHERENCE TO TREATMENT Viral and autoimmune pathologies 7