CURRICULUM VITAE. Jyrki K. Virtanen

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1 CURRICULUM VITAE Jyrki K. Virtanen Date of birth: July 7, 1973 Address: 75 St. Alphonsus St., unit #1805 Place of birth: Hausjärvi, Finland Boston, MA 02120, USA Marital status: common-law marriage (Tulliportinkatu 12 A 19, Kuopio, Finland) Nationality: Finnish (work) Military rank: corporal in the Finnish (mobile) conscript army (fax) [email protected] [email protected] (personal) EDUCATION PhD in nutritional epidemiology, University of Kuopio, Research Institute of Public Health, Kuopio, Finland. The subject of the thesis: Homocysteine, folate and cardiovascular diseases MSc in Health Sciences, clinical nutritionist, University of Kuopio. Pro Gradu-thesis: The Effects of Creatine Supplementation on Exercise Performance and Body Composition. The experimental phase of the study was done in the University of Limburg, Maastricht, The Netherlands between 1/1999 7/1999. Fall 1992 Basic Course in Sports Instruction, Varala College of Sports Education, Tampere, Finland Upper secondary school, Hausjärvi, Finland Comprehensive school, Hausjärvi, Finland. WORK EXPERIENCE 9/05 - Researcher. Harvard School of Public Health, Department of Nutrition, Boston, USA. 4/02 - Nutrition instructor and consultant to the Finnish personal trainers of the European Elixia fitness club chain. 1/00 Researcher. University of Kuopio, Research Institute of Public Health. 6/00 7/00 Practical training in nutritional therapy (hospital), Kuopio University Hospital. 4/00 5/00 Practical training in nutritional therapy (health centre), Health Centre of Lieksa. 10/99 1/00 Laboratory work, University of Kuopio, Research Institute of Public Health.

2 1/98 2/98 Practical training in catering (hospital kitchen), Västerås central hospital, Västerås, Sweden. LANGUAGE PROFICIENCY Finnish (native tongue), English (fluent), Swedish (basics), German (basics), French (basics). MEMBER OF THE STUDY GROUPS Health Professionals Follow-up Study, Harvard School of Public Health, Nurses Health Study, Harvard School of Public Health, Kuopio Ischaemic Heart Disease Risk Factor Study, KIHD, The effect of olive oil consumption on oxidative damage in European populations, EUROLIVE, 2002-, PI in Finland. Antioxidant Supplementation in Atherosclerosis Prevention (ASAP) Study, The effects of catechin enriched rye bread on serum lipids and their oxidation: a randomized double blind study, The effect of catechin enriched chocolate, dark chocolate and white chocolate on human serum lipids and their oxidation: a clinical trial, The effects of flavonoid supplementation on serum lipids and their oxidation, randomized double blind study, The effects of coffee drinking on the oxidation of human serum lipids: a clinical trial, MEMBERSHIPS INTERESTS -American Society for Nutritional Sciences, The Finnish Society of Epidemiology, American Heart Association s Council of Epidemiology, The Finnish Society for Nutrition Research, The Association of Clinical and Public Health Nutritionists of Finland, Agronomiliitto (trade union), 1998 Sports (gym, golf, beach volley, rollerblading), colored pencil art (From the Tip of My Pencil:

3 PRESENTATIONS -Mercury accumulation and progression of carotid atherosclerosis: the prospective 11-year follow-up study in men in eastern Finland. Experimental Biology 2005 Annual Meeting and the XXXV International Congress of Physiological Sciences , San Diego, USA. Poster. -Mercury and CVD. Physicians for Social Responsibility meeting about the effects of mercury on vardiovascular diseases. Washington, DC, February 1, Homocysteine is a Risk factor for Stroke: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. 44th Annual Conference on Cardiovascular Disease Epidemiology and Prevention, San Francisco, USA, March 3-6, Poster. -Homocysteine as a Risk Factor for CVD Mortality in High-Risk Study. 4th International Conference on Homocysteine Metabolism, Basel, Switzerland, June 29-July 3, Poster. -Homocysteine as a Risk Factor for CVD Mortality in High-Risk Study. 43 rd Annual Conference on Cardiovascular Disease Epidemiology and Prevention, Miami, USA, March 5-8, Poster. -Hair Content of Mercury and Risk of cardiovascular and Coronary Heart Disease Mortality: The Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. 42 nd Annual Conference on Cardiovascular Disease Epidemiology and Prevention, Honolulu, Hawaii, April , Poster. -Dietary Methionine and Serine Intake and the Risk of Acute Coronary Events: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. Homocysteine Metabolism, 3 rd International Conference, Sorrento, Italy, July 1 5, Oral presentation. -Low Folate Intake is Associated with an Excess Incidence of Acute Coronary Events: The Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD). Homocysteine Metabolism, 3 rd International Conference, Sorrento, Italy, July 1-5, Poster. -High Dietary Methionine Intake Is Associated With an Increased Incidence of Acute Coronary Events: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. American Heart Association s 73 rd Scientific Sessions, New Orleans, USA, November 13-15, Poster was in the finals of the top eleven posters in the Population Science category. -Low Dietary Folate Intake is Associated with an Excess Incidence of Acute Coronary Events: The Kuopio Ischaemic Heart Disease Risk Factor Study (KIHD). American Heart Association s 73 rd Scientific Sessions, New Orleans, USA, November 13-15, Oral presentation. -High Dietary Methionine Intake Is Associated With an Increased Incidence of Acute Coronary Events: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. Scientific meeting of the Finnish Atherosclerosis Club, Oral presentation.

4 PUBLICATIONS Virtanen JK, Rissanen TH, Voutilainen S, Tuomainen T-P. Mercury and cardiovascular diseases. Review. J Nutr Biochem, Submitted. Virtanen JK. Homocysteine, Folate and Cardiovascular Diseases. Doctoral dissertation. Kuopio University Publications D. Medical Sciences 362. Kuopio ISBN p. Virtanen JK, Voutilainen S, Alfthan G, Korhonen MJ, Rissanen TH, Mursu J, Salonen JT. Homocysteine as a Risk Factor for CVD Mortality in High-Risk Men: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. J Intern Med 2005, 257: Virtanen JK, Voutilainen S, Happonen P, Alfthan G, Kaikkonen J, Mursu J, Rissanen TH, Kaplan GA, Korhonen MJ, Sivenius J, Salonen JT. Homocysteine, folate and risk of stroke: Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. Eur J Cardiovasc Prev Rehabil 2005, 12: Virtanen JK, Voutilainen S, Rissanen TH, Happonen P, Mursu J, Laukkanen JA, Poulsen H, Lakka TA, Salonen JT. Dietary Methionine Intake and the Risk of Acute Coronary Events: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. Nutr Metab Cardiovas Dis In press. Virtanen JK, Voutilainen S, Rissanen TH, Mursu J, Tuomainen T-P, Korhonen MJ, Valkonen V-P, Seppänen K, Laukkanen JA, Salonen JT. Mercury, Fish Oils, and Risk of Acute Coronary Events and Cardiovascular, Coronary Heart Disease and All-Cause Mortality in Study. Arterioscler Thromb Vasc Biol 2005;25: Rissanen TH, Virtanen JK. Editorial: Mercury as a cardiovascular risk factor. Eur J Lipid Sci Technol 2003, 105, 113. Voutilainen S, Virtanen JK, Rissanen TH, Alfthan G, Laukkanen J, Nyyssönen K, Mursu J, Valkonen V-P, Tuomainen T-P, Kaplan GA, Salonen JT. Serum folate and homocysteine and incidence of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Clin Nutr 2004;80: Voutilainen S, Rissanen TH, Virtanen JK, Lakka TA, Salonen JT. Low Dietary Folate Intake Is Associated with an Excess Incidence of Acute Coronary Events: the Kuopio Ischaemic Heart Disease Risk Factor Study. Circulation 2001;103: Voutilainen S, Rissanen TH, Virtanen JK, Porkkala-Sarataho E, Kaikkonen J, Seppänen K, Tuomainen T-P, Lehtimäki T, Rontu R, Hämelahti P, Penttilä I, Mursu J, Salonen JT. Folic acid supplementation increases serum paraoxonase activity: evidence from a double-blind oral supplementation trial in men. Current Topics in Nutraceutical Research 2003;1:

5 Voutilainen S, Rissanen T, Virtanen J, Lakka TA, Salonen JT. Low dietary folate intake is associated with an excess incidence of acute coronary events: the Kuopio Ischaemic Heart Disdease Risk Factor (KIHD) Study. In: Nutrition and metabolism, collected scientific articles Edited Prof. A G Moiseenok, Grodno, ISBN p. Venho B, Voutilainen S, Valkonen V-P, Virtanen J, Lakka TA, Ovaskainen M-L, Laitinen M, Salonen JT. Association Between Arginine Intake, Blood Pressure, and the Risk of Acute Coronary Events in Men: the Kuopio Ischaemic Heart Disease Risk Factor Study. Am J Clin Nutr 2002;76: Rissanen TH, Voutilainen S, Virtanen JK, Vanharanta M, Mursu J, Venho B, Salonen JT. Fruit, Berry and Vegetable Intake and Mortality: the Kuopio Ischaemic Heart Disease Risk Factor (KIHD) Study. J Nutr 2003;133: Mursu J, Voutilainen S, Nurmi T, Helleranta M, Rissanen TH, Nurmi A, Kaikkonen J, Porkkala-Sarataho E, Nyyssönen K, Virtanen JK, Salonen R, Salonen JT. Polyphenol-rich phloem enhances the resistance of total serum lipids to oxidation in men. J Agric Food Chem 2005;53: Mursu J, Voutilainen S, Nurmi T, Rissanen TH, Virtanen JK, Kaikkonen J, Nyyssönen K, Salonen JT. Dark chocolate consumption increases HDL cholesterol concentration and chocolate fatty acids may inhibit lipid peroxidation in healthy humans. Free Radic Biol Med 2004;37: Mursu J, Voutilainen S, Nurmi T, Alfthan G, Virtanen JK, Rissanen TH, Happonen P, Nyyssönen K, Kaikkonen J, Salonen R, Salonen JT. The effects of coffee consumption on lipid peroxidation and plasma total homocysteine concentrations: a clinical trial. Free Radic Biol Med 2005;38: Jyrki Virtanen, Patrik Borg, Jaakko Mursu. Lisäravinteet nykytilanne. (Sports supplements present situation.) Urheilijan Ravinto 3:50-55, Jyrki Virtanen. Kreatiinistako lisätehoa? (More power with creatine?) Urheilijan Ravinto 2:26-30, 2001.