Research profile: Publications:
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- Daniel Miles
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1 Personal data: Date and place of birth: 30 th of November, 1975, Aarhus, Denmark. Civil status: Married and have two children. Private address: Bronzealdervej 57, DK Aarhus V, Education: 2000 B.Sc. in Biology, Aarhus University, Denmark M.Sc. in Molecular Biology from the laboratory of Professor Jan J. Enghild at the Department of Molecular Biology, Aarhus University, Denmark Ph.D. degree obtained from the Faculty of Science, Aarhus University, Denmark. Research conducted in the laboratory of Jan J. Enghild, Department of Molecular Biology. Employment: Research profile: Publications: Postdoctoral fellow in the Enghild group, Department of Molecular Biology and Genetics, Aarhus University, Denmark Supported by: 2006: Danish Cancer Society (PI Jan J. Enghild (JJE)) : The Carlsberg foundation (individual postdoctoral grant) 2009: The Danish Council for Independent Research, Medical Sciences (JJE) Senior Advisor in the Enghild group, Department of Molecular Biology and Genetics, Aarhus University, Denmark Supported by: : The Danish Council for Strategic Research. The Programme Commission on Health, Food, and Welfare (JJE). The research includes protein characterization (structure, function, activity) and proteomic studies. Protein research is conducted in collaboration with biologists, physicians, chemists, and bioinformaticians. Main area of interests: Extracellular matrix proteins and their interplay, proteolytic enzymes and their inhibitors, cancer- related biomarkers, and transcriptomics and proteomics studies of hitherto uncharacterized species. I have published 13 peer- reviewed articles in international journals since 2005 (please see pubmed), including 8 first authorships. In total, 5 of the publications were in the highly prestigious Journal of Biological Chemistry. In addition, Sanggaard et al., Mol Cell Proteomics, 11, made the cover of the top proteomics journal, Molecular and Cellular Proteomics (2012). 1
2 Technical experience: 1D and 2D gel electrophoresis, biological mass spectrometry (MALDI, LC- MS/MS, and de novo sequencing), protein and peptide purification (FPLC and HPLC), immunochemistry, N- terminal protein sequencing, and biochemical activity assays, molecular biology and bioinformatics tools. Supervision: Co- supervision of 4 B.Sc. students, 6 M.Sc. students, one laboratory technician, two PhD students and one Post doc Supervisor on high school project (SRP). Teaching experience: Teaching in the following courses located at Department of Molecular Biology and Genetics, at Interdiciplinary Nanoscience Center (inano), and at School of Engineering: Introduction to Molecular Biology, Experimental Molecular Biology, Advanced Biochemistry, General Biochemistry, Molecular Biotechnology, Proteomics, Applied Proteomics, Protein Biophysics, Protein Biotechnology, Bionanotools, and Experimental exercises in nanoscience: Analysis Of Protein Adsorption To Medical Implants/Biomaterials. Posters, abstracts, and invited talks/guest lectures: 14: Interdisciplinary Nanoscience Center (inano) autumn school, October 2012, Grenå, Denmark. Invited talk. 13: DuPont (former Danisco A/S). May Invited talk. 12: Applied proteomics, PhD- course at Aalborg University, March Guest lecture. 11: 2 nd Nordic Proteomics Symposium, 2011, Copenhagen, Denmark. Abstract and poster presentation. 10: Biannual meetings of the Novel Enzymes of Industrial Relevance (NOVENIA) - consortium, Poster presentation and talks. 9: Proteomics and Protein Profiling, 2010 and 2012, PhD course at Aarhus University Hospital. Guest lectures. 8: Society for Experimental Biology, Annual Main Meeting, 2010, Prag, Czech Republic. Abstract. 7: The 6th international Conference on Proteoglycan, Aix- les- Bains, 2009, France. Abstract and poster presentation. 6: Waters MS Technology Seminar, Brøndby, 2008, Denmark. Poster presentation. 2
3 5: Meeting of The Danish Society for Connective Tissue Biology, 2008, Odense University Hospital. Invited talk. 4: Annual meeting of the interdisciplinary nanoscience Center (inano), 2006, Aarhus University. Poster presentation. 3: Meetings of The Danish National Research Foundation Center for insoluble protein structures (inspin), Aarhus University Several oral presentations. 2: 1 st Latin American Protein Society Meeting, 2004, Angra dos Reis, Brazil. Abstract and poster presentation. 1: XIth Biennial Meeting of the Society for Free Radical Research International, 2002, Paris. Abstract and poster presentation. Non- peer reviewed publications / public service: 9: Interview to Videnskab.dk. January 2013 (Danish web- based magazine). Derfor kan firbenet tabe sin hale. naturvidenskab/derfor- kan- firbenet- tabe- sin- hale 8: Interview to Jyllandsposten, January 2013, (Danish newspaper). Firbenets hale er perforeret som en lokumsrulle. 7: Sanggaard et al paper presented in international media (NBC, National Geographic, Los Angeles times ) December E.g. do- lizar- tails- have- in- common- with- toilet- paper/ 6: Interview to Videnskabens verden, P1, DR, November 2012 (Danish national radio). j.- enghild/forskningsresultater- i- medierne/ 5: Interview to Jyllandsposten, September 2012, (Danish newspaper). Kødædende plante kortlagt. 4: Sanggaard KW, Wang T, Enghild JJ. Digestive enzymes from neglected species: Useful for food applications? Interdisciplinary Nanoscience Center (inano) Annual Report 2009, (popular science). 3: Interview to Polarfronten / Videnskab.dk, 1, 16-17, 2010 (Danish popular science magazine/danish web- based magazine). naturvidenskab/taranteller- og- ikka- sojler- gemmer- pa- nye- enzymer 2: Sonne- Schmidt CS, Sanggaard KW, Enghild JJ. Separation of oligosaccharides of hyaluronan. 2007, Product presentation of GE Healthcare product. GE Healthcare booklet: Years of experience in every column, 40. 1: Sanggaard, K. W. Defekte proteiner kan forklare barnløshed (Danish article). 2005, Aktuel Naturvidenskab (popular science magazine). 6, 11. 3
4 Other academic work: 2012 Assessment committee chairman for post doc position at Aarhus University Assisting ad hoc reviewer of FEBS- letter and FASEB J manuscripts. Workshops/seminars/symposiums: 2011 QTrap 5500 training course, AB Sciex, Aarhus University University Teaching Training, Aarhus University Executive Seminars in Analytical Chemistry (ESAC) in Copenhagen Danish Proteomic Society Annual Symposiums D- DIGE workshop, GE Biosciences, Aarhus University. National academic collaborators: Professor Jan J. Enghild, Department of Molecular Biology and Genetics and inano, Aarhus University. Ass. Professor Frans Mulder, Department of Chemistry and inano, Aarhus University. Professor Niels Christian Nielsen, Department of Chemistry and inano, Aarhus University. Professor Daniel Otzen, Department of Chemistry and inano, Aarhus University. Professor Troels Skrydstrup, Department of Chemistry and inano, Aarhus University. Ass. Professor Henrik Birkedal, Department of Chemistry and inano, Aarhus University. Professor Morten Høyer, Oncology, Aarhus University Hospital. Professor Lise B. Wogensen from Research laboratory of Biochemical Pathology at Aarhus University Hospital, Denmark. Professor Henning Andersen, Neurology, Aarhus University Hospital. Professor Mikkel Schierup, Bioinformatics, Aarhus University. Ass. Professor Trine Bilde, Department of Biological Science at Aarhus University, Denmark. Professor Tobias Wang from Department of Biological Science at Aarhus University, Denmark. Ass. Professor Henrik Karring, Institute of Chemical Engineering, Biotechnology and Environmental Technology, University of Southern Denmark. Professor Peter Højrup, Department of Biochemistry and Molecular Biology, University of Southern Denmark. Ass. Professor Peter Stougaard, Department of Plant and environmental science, University of Copenhagen. International academic collaborators: Dr. Ines Kreuzer, University of Würzburg, Germany. Professor Rainer Hedrich, University of Würzburg, Germany. Dr. Waltraud X. Schulze, Max Planc Institut für Molekulare Pflanzenphysiologie, Germany. Associated Professor, Hans- Georg Wisniewski from New York University School of Medicine, USA. Professor, Tim D. Oury from University of Pittsburg School of Medicine, USA. 4
5 Industrial collaborators: Dupont (former Danisco A/S): - Partner in the strategic research alliance Novenia, Proteomics- related consultant work, Associated with: Novel Enzymes of Industrial Relevance (NOVENIA), International collaborative project involving both academic and industrial partners. Center for Insoluble Protein Structure (InSPIN), Aarhus University. Interdisciplinary Nanoscience Center (inano), Aarhus University. Prizes and grants: 2011 Mizutani Foundation for glycoscience (co- applicant) The Novo Nordisk Foundation (co- applicant) Carlsberg Foundation Involved in writing and concept design of several successful large grant applications, including EU- FP7 grants and a large application to the Danish Council for Strategic Research (Novenia, total budget of 38,3 million dkr ( )) Carlsberg Foundation Novo Nordisk PhD Plus Prizes Pierre Honeré AC Plesner s trust fund The family Hede Nielsen foundation The Harboe foundation Anna and Jakob Jakobsens foundation The Oticon foundations ph.d. scholarships. Leadership (experience and education): Involved in the management of the NOVENIA- consortium (includes 12 partners), inclusive preparation of the program for the annual meetings and 2- days symposiums. Involved in project management of several scientific projects in Jan J. Enghild s laboratory The Aarhus School of Business, Innovationsledelse (Innovation and Management) Aarhus Business College, Ledelse og Samarbejde (Management and Co- operation). 5
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