Education and Biobanking as a Career Path

Transcription

1 Education and Biobanking as a Career Path Jim Vaught, Ph.D. Editor-in-Chief, Biopreservation and Biobanking Senior Research Fellow, International Prevention Research Institute

2 Traditional biobanking career path Biobanker directors usually came from other professions, e.g. pathology, epidemiology. My own experience as a NCI molecular epidemiology contract director; training in NCI Epidemiology Program Technical staff often were undergraduate biologists who, after a year or 2 working in a biobank, left for graduate or medical school. Education in biobanking was usually on the job training with SOPs. Since biobanking was not yet thought of as a science, little consideration was given to professional training and education.

3 February 2012 Cancer Epidemiology, Biomarkers & Prevention

4 Professionalization comes to biobanking Degree Programs & Beyond: 2012 editorial Evolved from need to integrate biobank training within multiple disciplines: Pathology, clinical chemistry, epidemiology, biochemistry, molecular biology, etc. Masters program at Catholic University Lyon (Gormally et al) Other degree programs being discussed in this session ISBER proficiency testing and other educational programs College of American Pathologists BiorepositoryAccreditation Program

5 2011 ESBB meeting abstracts: September 2011 Biopreservation & Biobanking

6 Upcoming Textbook With co-editors Pierre Hainaut, Markus Pasterk, Kurt Zatloukal& Jim Vaught Introduction - Why Biobanking?/types of biobanks Molecular biomarkers in research and precision medicine Designing biobanks Establishment of BRCs national and international legal framework for Biobanks Cost-Benefit analysis of Biobanking Economic sustainability of Biobanks Ethics in Biosample collection and storage Governance and Public Engagement Ethics in the use of Biosamples Evaluating Biobank performance: biobank impact factors Training for biobanks - CPDs Master and PhD Programmes for Biobanking Ensuring effective utilisation of Biobanks success story HPV and cancer success story pathogens in collections before outbreakes Biobanking from a Patient perspective Biosafety and Biosecurity general laboratory safety applicable to biobanks Data management and LIMS Bioinformatics tools for Biobanking custodianship, benefit sharing and IP guidelines and SOPs access policy quality management certification processes collecting and managing clinical data Pre-analytics: the concept of Biobank Science

7 Nature Reviews Clinical Oncology, 2013

8 Figure 1 Workflow of next-generation biobanking, demonstrating the multidisciplinarity of the endeavour Basik, M. et al. (2013) Biopsies: next-generation biospecimens for tailoring therapy Nat. Rev. Clin. Oncol. doi: /nrclinonc

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11 Biobank Certification Program Improves and harmonizes biobanking standards for all types of biobanks Provides comprehensive education and required operational practices for biobank staff Requires biobanks to declare they will strive to comply with best practice standards

12 Biobank Education Program Comprehensive online education program addressing all aspects of biobanking 9 modules designed to provide 'how-to' knowledge for researchers and biobankers International flags mark country specific content Education Modules 1. Basics of Biobanking 2. Governance 3. Ethics 4. Facility Design and Safety 5. Quality Management and Process Improvement 6. Informed Consent 7. Biospecimen Collection and Processing 8. Biospecimen Storage and Distribution 9. Data Systems and Record Management

13 Biobank Tools and Templates Biospecimen User Fee Calculator Reliable and easy to use Captures operating expenses and biospecimen accrual data Calculates a user fee for specimen Biobanking Templates Over 30 customizable documents aligned with best practices Saves personnel time and money in creating biobank documents

14 Biobank Tools Biospecimen User Fee Calculator Reliable and easy to use Captures operating expenses and biospecimen accrual data Calculates a user fee for specimen Biospecimen Data Reporting Tool Allows biobanks to report biospecimen related data Based on BRISQ criteria Generates a report to be shared with samples upon release

15 College of American Pathologists Biorepository Accreditation Program Collaborators The CAP Biorepository Accreditation Program (BAP) integrates rigorous biorepository guidelines and best practices from: o International Society for Biological and Environmental Repositories--ISBER o NCI s Office of Biorepositories and Biospecimen Research (NCI/OBBR, now BBRB) o Organization for Economic Co-Operation and Development o Center for Medicare & Medicaid Services o College of American Pathologists College of American Pathologists 2012 College of American Pathologists. All rights reserved. 8

16 CAP s Biorepository Checklist 2012 College of American Pathologists. All rights reserved. College of American Pathologists 14

17 Conclusions Biobanking education has evolved over the past 10 years, and has taken many forms including: Degree programs Training and proficiency testing e.g. from ISBER Resource centers e.g. from CTRNet Publications e.g. Biobanking & Biopreservation Special issue on Biobanking Education being planned Textbooks Accreditation programs e.g. CAP All with an emphasis on professionalization to support new career paths

18 Jim Vaught, Editor-in-Chief Robert Hewitt, European Editor Biopreservation and Biobanking The official journal of: The International Society for Biological and Environmental Repositories