ALL-IN-ONE Optical Biometry, Dual Scheimpflug Tomography and Placido Topography

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1 ALL-IN-ONE Optical Biometry, Dual Scheimpflug Tomography and Placido Topography

2 GALILEI G6 Clinical Applications High confidence premium IOL selection The GALILEI G6 offers a link to the ray-tracing software packages PhacoOptics and Okulix. By taking into account the true physical properties of the eye and total corneal astigmatism, ray-tracing is the ideal tool for precise toric IOL planning.1 Corneal incision planning With high definition pachymetry, high order aberrations and total corneal astigmatism data, GALILEI offers a complete set for a precise planning and positioning of arcuate incisions for astigmatism correction in conjunction with cataract surgery.2

3 IOL selection for post-refractive cases GALILEI G6 is the first device on the market to combine the actual refractive data of the anterior and posterior corneal surfaces with intraocular distances and axial length measurements. With this complete dataset an exact ray-tracing of the eye can be performed to achieve accurate IOL power calculation in post-lasik and long or short eyes. In addition, the incorporated Shammas no-history formula for post-refractive cases enables a reliable IOL prediction even if no clinical history is available. 3 The GALILEI G6 Lens Professional also enables you to perform a complete topographic screening for refractive surgery: Corneal Implant Planning Planning and follow-up of Keratoplasty Keratoconus Screening

4 GALILEI G6 Unique Technology Placido Topography Highly accurate anterior curvature data Precise detection of anterior surface irregularities and tearfilm quality Optical Biometry State-of-the-art biometry measuring axial and intraocular distances in one exam session Lens thickness and precise anterior and posterior corneal power maps for next generation IOL planning Dual Scheimpflug Tomography Precise pachymetry and elevation data 3D anterior chamber analysis Ray-traced posterior corneal surface data to detect bulging and asymmetry in early stages

5 GALILEI G6 Clinical Benefits Workflow efficiency In one measurement session the GALILEI G6 Lens Professional acquires Placido topography, Scheimpflug tomography and optical biometry data for a comprehensive refractive and cataract screening. Acquiring and storing all clinical data in one device improves clinical workflow efficiency, reduces maintenance costs and saves office space. 4 Most complete dataset By providing high definition pachymetry as well as total corneal wavefront, curvature and astigmatism data of the anterior and posterior cornea, GALILEI G6 offers a comprehensive dataset to plan refractive and cataract applications. 5 Combined with optical biometry and a series of IOL calculation methods (Olsen PhacoOptics, Okulix, Shammas no-history), GALILEI G6 helps identifying the most suitable IOL for every patient. User friendly interface The new software of the GALILEI G6 offers an intuitive user interface with a live-view image of the eye for precise alignment of the exam and a 5 step measurement guidance for an improved workflow. The GALILEI G6 will also fully interface with your EMR system.

6 GALILEI PRODUCT FAMILY The modular solution for your needs Refractive Software Package Advanced GALILEI G6 Cataract Software Package Advanced GALILEI G6 Optional Software Licenses Advanced GALILEI G6 Refractive Report Keratoconus Report IOL Power Report Total Corneal Wavefront Report Curvature Topography Elevation Topography Densitometry Eye Metrics Report Map Comparison Report Biometry Report (including CCT, ACD, LT, AL) IOL Calculator* Advanced IOL Report Images Report Standard software package To be purchased separately Not available for this device IOL Calculator* Corneal inlay module DICOM/EMR connection Remote workstation CSV export for clinical studies Z-LASIK Report Santhiago PTA Report TM PhacoOptics / Okulix Connector** Please note: The Santhiago PTA Report TM and the Z-LASIK Report are not available for sale in the US. *IOL Formulae: Shammas no-history (post-refractive), Haigis, Holladay I, Hoffer Q, SRK I, SRK/T II **IOL Calculation Software: The GALILEI G6 connects to the third party ray-tracing software PhacoOptics (phacooptics.com) and Okulix (okulix.de).

7 GALILEI G6 System Information Measurement Ranges Axial Length: Central Corneal Thickness: Anterior Chamber Depth: Lens Thickness: Keratometry: White-to-White: Pupillometry: In-vivo Repeatability mm (default mm) μm mm mm D ( mm) 6 14 mm mm Parameter SD specified SD measured Axial Length: mm mm Central Corneal Thickness: 3.00 μm 1.13 μm Anterior Chamber Depth: mm mm Lens Thickness: mm mm Simulated Keratometry (SimK): 0.25 D 0.05 D Angle of flattest meridian: 10 3 White-to-White: mm mm Study Design Internal study of 24 normal eyes in 12 subjects, age range years (mean = 38 years). Repeatability as estimated by the mean standard deviation of consecutive measurements averaged over all subjects and eyes. Abbreviations Mean Arithmetic mean of consecutive measurements SD specified Specified repeatability as defined by the mean standard deviation SD measured Measured repeatability as estimated by the mean standard deviation SimK Keratometry corneal curvature over central area of diameter 1 4 mm Technical Data Placido disc: Measurement speed: Number of measurement points Scheimpflug/Placido: Displayed map coverage: 20 rings 60 images in 1 second up to measurement points max. 10 mm Measurement unit characteristics Measuring principle: Combination of optical A-Scan, Dual Scheimpflug slit images and placido and top view images Observation illumination: Scheimpflug illumination: NIR (near-infrared) LED 810 nm Blue LED (UV-free) 470 nm Placido illumination: NIR (near-infrared) LED 750 nm Biometry wavelength: Image acquisition: Electrical conditions Power requirement: Fuses (110/230 V): 880 nm Classification according to IEC Type of protection Class 1 against electric shock: Degree of protection against electric shock: Degree of protection against damaging penetration of water: 3 high definition CCD cameras VAC, 50/60 Hz, 400 W 2 T6, 3 AH, 250 VAC Type B applied part IP20

8 Discover your comfortable way to study! Register now for free: e-learning.ziemergroup.com Ziemer Ophthalmic Systems AG a Ziemer Group Company Allmendstrasse 11 CH-2562 Port, Switzerland Phone marketing@ziemergroup.com galilei.ziemergroup.com Disclaimer: The GALILEI G6 Lens Professional is pending FDA approval and is not available for sale in the US. For some other countries, availability may be restricted due to local regulatory requirements. Please contact Ziemer for details. Ziemer USA, Inc. a Ziemer Group Company 620 E. Third Street Alton, Illinois 62002, USA Phone usa@ziemergroup.com References 1 Hoffmann PC, Wahl J, Hütz WW, Preußner PR (2013). "A Ray Tracing Approach to Calculate Toric Intraocular Lenses" 29 (6): Pajic B (2013). "Planning a Procedure with LRIs" Supplement to Cataract and Refractive Surgery Today Europe October: Ziemer Ophthalmology (Deutschland) GmbH a Ziemer Group Company Im Hausgrün 15 DE Emmendingen, Germany Phone info-deutschland@ziemergroup.com 3 Shammas HJ, Shammas MC (2007). "No-history method of intraocular lens power calculation for cataract surgery after myopic laser in situ keratomileusis." Journal of Cataract and Refractive Surgery 33 (1): Fam HB (2013). "The Advantages of an All-in-One System." Supplement to Cataract and Refractive Surgery Today Europe October: Ziemer Ophthalmic Systems AG Actual product characteristics, specifications, and prices are subject to change. Issue Date: Document No. CM REF Zhang L, Sy ME, Mai H, Yu F, Hamilton DR (2015). "Effect of posterior corneal astigmatism on refractive outcomes after toric intraocular lens implantation" Journal of Cataract and Refractive Surgery 41 (1):

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