CURRICULUM VITAE. Research Interest: Gastrointestinal Pathology, Hepato-biliary pathology, Pancreas pathology

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1 CURRICULUM VITAE Personal Details Surname: OZERCAN First Name: Ibrahim Hanifi Academic title/position: Professor Key Qualifications: Research Interest: Gastrointestinal Pathology, Hepato-biliary pathology, Pancreas pathology International Experience/Collaborations: Contact Details Work Address: Name of Hospital: Firat University Hospital Street Town Country Elazığ Post Code Phone/Fax /2186 Date of Birth: Place and Country of Birth: Elazığ Country of Citizenship: Turkey Country of Training: Turkey First Language: Turkish Languages: English

2 Academic Details Faculty/University (name and address) Đstanbul Medicine Faculty/Đstanbul University ÇAPA/ISTANBUL Date of Graduation Postgraduate Training: (Name and address of Center and Supervisor[s] in charge of Training) SUPERVISOR IN CHARGE OF TRAINING: From 1992 To 1996 Title of thesis: The value of AgNOR and PCNA in the Differantial Diagnosis of Benign Hyperplasia and Adenocarcinoma of the Prostat Accreditation: (Name, number and date of certificate issued by University, Medical Association or Government Body) Academic Experience: Pathology Department Chairman July Elazığ Health Academy Director August Memberships: 1-The Turkish Society of Pathology 2-The Ege Society of Pathology International Publications: 1. Yekeler H, Ozercan MR, Yumbul AZ, Agan M, Ozercan IH. Nucleolar organizer regions in lymphomas: a quantitative study. Pathologica. 1993; 85(1097): Durmaz R, Aydin A, Koroglu M, Aker H, Ozercan IH, Atik E, Arici S. Detection and genotyping of Epstein-Barr virus by polymerase chain reaction in tissues obtained from cases with Hodgkin's disease in Turkey. Acta Virol ;42(6): Semerciöz A, Özercan ĐH, Baltacı AK, Moğolkoç R, Yılmaz B, Keleştimur H. Effectiviness of Hypotermia in Preventing Testicular Injury Following Testicular Torsion and Detorsion. Medical Science Resarch.1998; 26,

3 4. Bahçecioğlu ĐH, Demir A, Üstündağ B, Đlhan M, Baydaş G, Canatan H, Özercan Đ. Protective Effect of L-Carnitine on Alcholic Fatty Liver in Rats. Medical Science Research.1999; 27, Erdogan M, Ilhan YS, Akkus MA, Caboglu SA, Ozercan I, Ilhan N, Yaman M. Effects of L-thyroxine and zinc therapy on wound healing in hypothyroid rats. Acta Chir Belg ; 99(2): Bahçecioğlu ĐH, Üstündağ, Özercan Đ, Erçel E, Baydaş G, Akdere T, Demir A. Protective Effect of Ginkgo Biloba Extract on CCl4 Induced Liver Damage. Hepatology Research. 1999;15, Özercan ĐH, Bahçecioğlu ĐH, Özercan MR, Bozlak N, Yekeler H. Proliferating Cell Nuclear Antigen and Nucleolar Organizer Region for Differantial Diagnosis of Dysplasia and Adenocarcinoma in Gastric Biopsies. Indian J. Gastroenter. 2000;19, Tahmaz L, Gökalp A, Kibar Y, Koçak Đ, Yalçın O, Özercan Đ. Effect of Hypothyroidism on the Testes in Mature Rats and Treatment with Levothyroxine and Zinc. Andrologia.2000; 32, Kazez A, Demirbag M, Ustundag B, Ozercan IH, Saglam M. The role of melatonin in prevention of intestinal ischemiareperfusion injury in rats. J Pediatr Surg ;35(10): Ustundag B, Kazez A, Demirbag M, Canatan H, Halifeoglu I, Ozercan IH. Protective effect of melatonin on antioxidative system in experimental ischemia-reperfusion of rat small intestine. Cell Physiol Biochem. 2000;10(4): Rahman A, Ustunda B, Burma O, Ozercan IH, Cekirdekci A, Bayar MK. Does aprotinin reduce lung reperfusion damage after cardiopulmonary bypass? Eur J Cardiothorac Surg ;18(5): Ozercan IH, Cobanoglu B, Simsek M, Dogan C, Ozercan MR. Epidermoid cyst of the ovary: a case report. Pathologica ;92(4): Kabakus N, Serhatlioglu S, Akfirat M, Kazez A, Aydinoglu H, Ozercan I, Aygun AD. Prune-belly syndrome associated with extra-abdominal abnormalities in a 7-year-old boy. Turk J Pediatr. 2000;42(2): Erol FS, Özveren MF, Özercan ĐH, Topsakal C, Akdemir Đ. Primary Ewing s Sarcoma of the Occipital Bone-Case Report. Neurol. Med. Chir.2001; 41, Rahman A, Üstündağ B, Burma O, Özercan ĐH, Erol FS. Neuroprotective Effect of Regional Carnitine on Spinal Cord Ischemia- Reperfusion Injury. Eu. J. Cardio Thoracic Surg. 2001;20, Đlhan N, Halifeoğlu Đ, Özercan ĐH, Đlhan N. Tissue malon aldehyde and adenosine triphosphatase level after experimental liver iscaemia- reperfusion damage. Cell Biochem Funct. 2001; 19: Topsakal C, Erol FS, Özercan Đ, Murat A, Gürateş B. Presakral Solitary Giant Neurofibroma Without Neurofibromatosis Type 1 Presenting as pelvic mass (Case Report). Neurol med- chir, 2001;41, Topsakal C, Akdemir Đ, Tıftıkçı M, Özercan Đ, Aydın Y. Malignant Schwannoma of the sciatic Nerve Originating in a Spinal Plexiform Neurofibroma Associated With Neurofibromatosis Type 1 Case Report. Neurol med- chir. 2001;41, Bulbuller N, Akkus MA, Cetinkaya Z, Ilhan YS, Ozercan I, Kirkil C, Dogru O. Effects of melatonin and lactulose on the liver and kidneys in rats with obstructive jaundice. Pediatr Surg Int (8): Demir T, Turgut B, Akyol N, Ozercan I, Ulas F, Celiker U. Effects of amniotic membrane transplantation and mitomycin C on wound healing in experimental glaucoma surgery.ophthalmologica ;216(6): Kazez A, Ozercan IH, Erol FS, Faik Ozveren M, Parmaksiz E. Sacrococcygeal heart: a very rare differentiation in teratoma.eur J Pediatr Surg Aug;12(4): Celiker U, Ilhan N, Ozercan I, Demir T, Celiker H. Octreotide reduces ischaemia-reperfusion injury in the retina.acta Ophthalmol Scand. 2002;80(4):

4 23.Topsakal C, Bulut S, Erol FS, Ozercan I, Yildirim H. Chordoma of the thoracic spine--case report.neurol Med Chir (Tokyo) Apr;42(4): Topsakal C, Kaplan M, Erol F, Cetin H, Ozercan I. Unusual arachnoid cyst of the quadrigeminal cistern in an adult presenting with apneic spells and normal pressure hydrocephalus--case report.neurol Med Chir (Tokyo) ;42(1): Cetinkaya Z, Ulger H, Akkus MA, Dogru O, Cifter C, Doymaz MZ, Ozercan IH. Influence of some substances on bacterial translocation in the rat.world J Surg ;26(1): Celik H, Ayar A, Tug N, Simsek M, Ozercan I, Cikim G, Bildirici I. Effects of melatonin on noncardiogenic pulmonary edema secondary to adnexial ischemia-reperfusion in guinea pig.neuro Endocrinol Lett ; 23(2): Demir T, Ulas F, Ozercan I, Ilhan N, Celiker U, Yasar MA. Protective effects of pentoxifylline in retinal ischemia/reperfusion injury. Ophthalmologica. 2003;217(5): Bulbuller N,Çetinkaya Z, Akkus MA, Cifter C, Đlhan YS, Dogru O, Aygen E, Ozercan I, Genç K. The effects of melatonin and prostaglandin E-1 analogue on experimental hepatic ischaemia reperfusion damage.đnternational Journal of Clinical practice. 2003; 57(10): Demir T, Turgut B, Celiker U, Ozercan I, Ulas F, Akyol N. Effects of octreotide acetate and amniotic membrane on wound healing in experimental glaucoma surgery. Doc Ophthalmol ;107(2): Yilmaz T, Kukner AS, Aydemir O, Ozercan IH, Naziroglu M. Aprotinin reduces ischemia-reperfusion injury in the retina of guinea pigs. Eur J Ophthalmol ;13(7): Yilmaz S, Ozan S, Ozercan IH. Comparison of pyruvate kinase variants from breast tumor and normal breast.arch Med Res ;34(4): Ozercan IH, Okur MI, Coskun F, Yıldırım AM. Malignant fibrous histiocytoma and squamous carcinoma derived from a burn scar.acta Chir Belg ;104(6): Bahcecioglu IH, Yalniz M, Ataseven H, Bulbuller N, Kececi M, Demirdag K, Ozercan I, Ustundag B. TNF-alpha and leptin in experimental liver fibrosis models induced by carbon tetrachloride and by common bile duct ligation.cell Biochem Funct ;22(6): Yilmaz T, Naziroglu M, Celebi S, Ozercan HI, Kukner AS. Administration of high dose intravitreal melatonin degenerates retinal cells in guinea pigs.pathophysiology ;11(2): Ozel SK, Apak S, Ozercan IH, Kazez A. Giant mesenteric lipoma as a rare cause of ileus in a child: report of a case.surg Today. 2004;34(5): Demirdag K, Bahcecioglu IH, Ozercan IH, Ozden M, Yilmaz S, Kalkan A. Role of L-carnitine in the prevention of acute liver damage induced by carbon tetrachloride in rats.j Gastroenterol Hepatol Mar;19(3): Erol FS, Topsakal C, Ozveren MF, Kaplan M, Ilhan N, Ozercan IH, Yildiz OG. Protective effects of melatonin and vitamin E in brain damage due to gamma radiation: an experimental study. Neurosurg Rev ;27(1): Aydin S, Halifeoglu I, Ozercan IH, Erman F, Kilic N, Aydin S, Ilhan N, Ilhan N, Ozkan Y, Akpolat N, Sert L, Caylak E. A comparison of leptin and ghrelin levels in plasma and saliva of young healthy subjects. Peptides ;26(4): Aydin S, Ozercan IH, Dagli F, Aydin S, Dogru O, Celebi S, Akin O, Guzel SP. Ghrelin immunohistochemistry of gastric adenocarcinoma and mucoepidermoid carcinoma of salivary gland. Biotech Histochem. 2005; 80(3-4): Bahcecioglu IH, Yalniz M, Ataseven H, Ilhan N, Ozercan IH, Seckin D, Sahin K. Levels of serum hyaluronic acid, TNF-alpha and IL-8 in patients with nonalcoholic steatohepatitis. Hepatogastroenterology ;52(65):

5 41.Bulgan Kilicdag E, Ay G, Celik A, Ustundag B, Ozercan I, Simsek M. Oxidant-antioxidant system changes relative to placentalumbilical pathology in patients with preeclampsia. Hypertens Pregnancy. 2005;24(2): Bahcecioglu IH, Yalniz M, Ilhan N, Ataseven H, Ozercan IH. Levels of serum vitamin A, alpha-tocopherol and malondialdehyde in patients with non-alcoholic steatohepatitis: relationship with histopathologic severity. Int J Clin Pract ;59(3): Kokcam I, Ozercan IH. A case of linear lichen planus. J Dermatol. 2005, 32(9): Aydın S, Ozercan IH, Aydın S, Özkan Y, Dagli F, Oguzoncul F, Geckıl H. Biological rhythm of saliva ghrelin in humans. Biological Rhythm Research 2006; 37(2): Aydın S, Geckil H, Zengin F, Ozercan ĐH, Karatas F, Aydin S, Balik DT, Özkan Y, DagliF, Celik V. Ghrelin in plants: what is the function of an appetite hormone in plants?. Peptides. 2006; 27(7): Ozercan IH, Dagli AF, Ustundag B, Ozercan MR, Bahcecioglu IH, Celik H, Yalniz M, Poyrazoglu OK, Ataseven H. Does instant coffee prevent acute liver injury induced by carbon tetrachloride (CCl(4))? Hepatol Res Jul;35(3): Onderci M, Sahin N, Sahin K, Cikim G, Aydin A, Ozercan I, Aydin S. Efficacy of supplementation of alpha-amylase-producing bacterial culture on the performance, nutrient use, and gut morphology of broiler chickens fed a corn-based diet. Poult Sci. 2006; 85: Cetinkaya Z, Esen K, Ozercan IH, Ustundag B, Ayten R, Aygen E.The effect of Bosentan on healing of colonic anastomosis. World J Emerg Surg ;1: Ilkay E, Tirikli L, Ozercan I, Yavuzkir M, Karaca I, Rahman A, Arslan N. Oral mycophenolate mofetil prevents in-stent intimal hyperplasia without edge effect. Angiology Oct-Nov;57(5): Yılmaz T, Aydemir O, Özercan ĐH, Üstündag B. Effects of Vitamin E, Pentoxifylline and Aprotinin on Light-Đnduced Retinal Đnjury.Ophthalmologica. 2007;221(3): Yalnız M, Bahcecioglu ĐH, Kuzu N, ÇelebiN, Ataseven H,Üstündağ B, Özercan ĐH, Şahin K. Amelioration of Steatohepatitis with Pentoxyfilline in a Novel Nonalcoholic Steatohepatitis Model Đnduced by High Fat Diet. Digestive Diseases and Sciences ;52(9): Yalnız M, Bahcecioglu ĐH, Kuzu N,Poyrazoğlu OK, Bulmuş O,Çelebi S,Üstündağ B,Özercan ĐH, Şahin K. Preventive role of Genistein in an experimental non-alcolic steatohepatitis model. J Gastroenterol Hepatol. 2007;22(11): Üstündağ B, Bahcecioglu ĐH, Sahin K, Duzgun S, Koca S, Gulcu F, Özercan ĐH. Protective Effect of Soy Isoflavones and Arylesterase in the Experimental Nonalcoholic Steatohepatitis Model. Dig Dis Sci. 2007; 52 (8): Aydin S, Ozercan IH, Geckil H, Dagli F, Aydin S, Kumru S, Kilic N, Sahin I, Ozercan MR. Ghrelin is present in teeth. J Biochem Mol Biol. 2007;40(3): Kuzu N, Metin K, Dagli AF, Akdemir F, Orhan C, Yalniz M, Ozercan IH, Sahin K, Bahcecioglu IH. Protective role of genistein in acute liver damage induced by carbon tetrachloride. Mediators Inflamm. 2007;: Karlidag T, Cobanoglu B, Keles E, Alpay HC, Ozercan I, Kaygusuz I, Yalcin S, Sakallioglu O. Expression of Bax, p53, and p27/kip in patients with papillary thyroid carcinoma with or without cervical nodal metastasis. Am J Otolaryngol. 2007;28(1): Gamze K, Mehmet HM, Deveci F, Turgut T, Ilhan F, Ozercan I. Effect of bosentan on the production of proinflammatory cytokines in a rat model of emphysema. Exp Mol Med Oct 31;39(5): Sahin K, Onderci M, Tuzcu M, Ustundag B, Cikim G, Ozercan IH, Sriramoju V, Juturu V, Komorowski JR.Effect of chromium on carbohydrate and lipid metabolism in a rat model of type 2 diabetes mellitus: the fat-fed, streptozotocin-treated rat. Metabolism. 2007;56(9): Bahcecioglu IH, Koca SS, Poyrazoglu OK, Yalniz M, Ozercan IH, Ustundag B, Sahin K, Dagli AF, Isik A. Hepatoprotective effect of infliximab, an anti-tnf-alpha agent, on carbon tetrachloride-induced hepatic fibrosis. Inflammation. 2008;31(4):

6 60. Erol FS, Kaplan M, Tiftikci M, Yakar H, Ozercan I, Ilhan N, Topsakal C. Comparison of the effects of octreotide and melatonin in preventing nerve injury in rats with experimental spinal cord injury. J Clin Neurosci Jul;15(7): Aygen B, Dursun FE, Dogukan A, Ozercan IH, Celiker H. Hypokalemic quadriparesis associated with renal tubular acidosis in a patient with Sjögren's syndrome. Clin Nephrol Apr;69(4): Ozbay Y, Aydin S, Dagli AF, Akbulut M, Dagli N, Kilic N, Rahman A, Sahin I, Polat V, Ozercan HI, Arslan N, Sensoy D. Obestatin is present in saliva: alterations in obestatin and ghrelin levels of saliva and serum in ischemic heart disease. BMB Rep Jan 31;41(1): Gozeri E, Celik H, Ozercan I, Gurates B, Polat SA, Hanay F.The effect of circadian rhythm changes on fetal and placental development (experimental study). Neuro Endocrinol Lett Feb;29(1): Koca SS, Isik A, Ozercan IH, Ustundag B, Evren B, Metin K.Effectiveness of etanercept in bleomycin-induced experimental scleroderma. Rheumatology (Oxford). 2008;47(2): Koca SS, Bahcecioglu IH, Poyrazoglu OK, Ozercan IH, Sahin K, Ustundag B. The treatment with antibody of TNF-alpha reduces the inflammation, necrosis and fibrosis in the non-alcoholic steatohepatitis induced by methionine- and choline-deficient diet. Inflammation Apr;31(2): Kuzu N, Bahcecioglu IH, Dagli AF, Ozercan IH, Ustündag B, Sahin K. Epigallocatechin gallate attenuates experimental nonalcoholic steatohepatitis induced by high fat diet. J Gastroenterol Hepatol. 2008;23(8 Pt 2):e Ozercan I.H., Sahin N., Akdemir F., Onderci M., Seren S., Sahin K., Kucuk O. Chemoprevention of fibroid tumors by [-]- epigallocatechin-3-gallate in quail Nutrition Research, 2008;28 (2): Ayten R, Cetinkaya Z, Girgin M, Ozercan I, Ustundag B, Aygen E.The Effects of Intraperitoneal Sildenafil Administration on Healing of Left Colonic Anastomoses and Intra-Abdominal Adhesion Formation in the Presence of Intra-Abdominal Infection. Dis Colon Rectum Jul 8. Presentations at International Scientific Meetings 1- Crabbe MJC, Üstündag B, Cay M, Naziroğlu M., Ilhan N. Özercan Đ.H, Dilsiz N., "Effects of vitamin E on serum glucose levels and nephropathy in streptozotocin-diabetic rats" The 6th International Symposium on the Maillard Reaction,London, , (1997). 2- Canatan H, Üstündağ B, Karataş F, Bahçecioğlu ĐH, Özercan Đ. Protective effect of Melatonin on oxidant and antioxidant systems in ethanol-induced liver damage Free Radicals, nitric Oxide and Antioxidants in Health and Disease,September ,Antalya TURKEY. 3- Çeliker Ü, Özercan Đ. The Effect of L-Carnitine on Nitric Oxide and Lipid Peroxidation in Retinal Đschemia-Reperfusion Injury. XIII. Congress of the European Society of Ophthalmology, 382, 3-7 June 2001,Istanbul-Turkey.