No. Acronym Full Title Institution Department Elegibility Note. Department of Molecular and Translational Medicine

Transcription

1 3 LightingPD Light-Induced Neurodegeneration, an Innovative Approach to Model Parkinson s Disease Universty of L'Aquila Biotechnological and Applied Clinical Sciences Department 3 LightingPD Light-Induced Neurodegeneration, an Innovative Approach to Model Parkinson s Disease University of Brescia Department of Molecular and 7 CircProt 7 CircProt 25 MICROMEGAP 26 TrKTruncAD Synaptic CIRCuit PROTection in AD and HD: BDNF and National Council TrkB signaling as rescue factors Institute of Biophysics Synaptic CIRCuit PROTection in AD and HD: BDNF and University of Milano TrkB signaling as rescue factors Department of Biosciences MICRObiome, MEtabolomics, epigenetics And Parkinon's Human Genetic Foundation Torino Molecular and Genetic Epidemiology BDNF receptor truncation as a determinant for Department of Physiology and Università degli studi "La Sapienza" Alzheimer s Disease pathophysiology Pharmacology 30 MeMoNd Metal-enhanced Models of Neurodegeneration 31 NAB3 Development of a Novel Multicellular In Vitro Model of Alzheimer s -like Blood-Brain Barrier Mario Negri Institute for Pharmacological Dept. Neuroscience, Lab. Molecular Neurobiology University of Milano-Bicocca (UNIMIB) Department of Health Sciences (DISS) 33 CEREBROFUT CHOLESTEROL EFFLUX CAPACITY OF CEREBROSPINAL FLUID AND SERUM AS POTENTIAL FUNCTIONAL MARKER OF ALZHEIMER DISEASE University of Parma Department of Pharmacy 34 CrackAND 34 CrackAND 41 PLAMIMAD 41 PLAMIMAD Cracking the Apoptosis Code in the Cracking the Apoptosis Code in the Platelets, misfolded proteins and matrix metalloproteinases as causative factors of Platelets, misfolded proteins and matrix metalloproteinases as causative factors of University of Catania Department of Mathematics and Computer Science Italian National Council Institute of Neurological Sciences University of Perugia Department of, Section of Internal and Cardiovascular University of Pavia Department of Biology and Biotechnology 43 AR-HIGHQ TARGETING NATIVE PROTEIN FUNCTION OF POLYGLUTAMINE ANDROGEN RECEPTOR TO IDENTIFY VEL THERAPEUTIC STRATEGIES FOR SPINAL AND BULBAR MUSCULAR ATROPHY Università degli Studi di Trento Centre for Integrative Biology (CIBIO)

2 44 ModelPolyQ Advanced models of polyglutamine disorders (HD, SCA2, SCA3, SCA7) University of Milan Department of Biosciences, Laboratory of Stem Cell Biology and Pharmacology of 45 Lyso-Park 49 AIRPAD The role of the autophagy-lysosomal pathway in Parkinson's INTERACTION AMONG AIR POLLUTION, GENETIC AND EPIGENETIC RISK FACTORS AS PATHOGENETIC MECHANISMS OF ALZHEIMER S DISEASE FONDAZIONE TELETHON TIGEM - TELETHON INSTITUTE OF GENETICS AND MEDICINE University Milano-Bicocca Department of Health Science DISS 49 AIRPAD INTERACTION AMONG AIR POLLUTION, GENETIC AND EPIGENETIC RISK FACTORS AS PATHOGENETIC MECHANISMS OF ALZHEIMER S DISEASE University of Milano Department of Medical Biotechnology and 50 CureALS Stress granules and proteostasis in motor neurons: towards a mechanistic understanding of ALS Università degli Studi di Modena e Reggio Emilia Università degli Studi di Modena e Reggio Emilia 50 CureALS Stress granules and proteostasis in motor neurons: towards a mechanistic understanding of ALS Universita' degli studi di Milano Dipartimento di Scienze Farmacologiche e Biomolecolari 53 ALSS100B An experimental model of ALS to study the UNIVERSITA' CATTOLICA DEL SACRO modulatory role of S100B protein in the inflammatory CUORE response and in motor neuron degeneration Institute of Anatomy and Cell Biology 56 NeuroAging Aging-regulating pathways as novel therapeutic targets for neurodegenerative s Telethon Foundation Telethon Institue of Genetics and Medicien (TIGEM) 64 ADiPNUT Alzheimer Disease-iPSC models to define the role of nutrients in neurodegeneration Università degli Studi di Padova Laboratorio di Oncoematologia, Dipartimento di Salute della Donna e del Bambino 64 ADiPNUT Alzheimer Disease-iPSC models to define the role of nutrients in neurodegeneration Università Politecnica delle Marche Dipartimento di Scienze Cliniche Specialistiche ed Odontostomatologiche, Sez. Biochimica, Facoltà di Medicina 66 AUTOREL 68 NeuroMit New mouse models for understanding the role of autophagy and its regulation by Reelin in Model systems to examine the role of mitochondrial dysfunction in neurodegeneration. University of Turin Department of Veterinary Sciences Università di Padova Dipartimento di Biologia

3 76 TARGET Targeting tau and amyloid synaptic transmission in humanized animal models Universita degli Studi di Roma Tor Vergata Department of System 85 REfrAME Pathway complexities of protein misfolding in neurodegenerative s: a novel approach to risks evaluation and model development Scuola Internazionale Superiore di Studi Avanzati-SISSA SISSA-Department of Neuroscience 87 NeuroMetal 88 LOADMIR Targeting trace metal status in neurodegenerative disorders MiRNAs in Alzheimer's Disease: pathogenic pathways and genetic vulnerability University of Modena and Reggio Emilia Department of Life Sciences CNR National Council-Institute of Cell Biology and Neurobiology, Italy Institute of Cell Biology and Neurobiology 91 BETASILVER Enhancement and further characterization of rat betaamyloid infusion model by concomitant treatment University of L'Aquila with silver nanoparticles Department of Life, Health and Environmental Sciences 94 STAD Synapse-to-nucleus communication in Alzheimer's Università degli Studi di Milano Department of Pharmacological and Biomolecular Sciences 99 3DMinBrain High-Throughput, High-Content Screening of human neuroectodermal organoids for innovative drug discovery in neurodegenerative s Scuola Internazionale Superiore di Studi Avanzati-SISSA SISSA-Department of Neuroscience 106 MoFENIB Advanced models for the dementia FENIB MIUR 108 PROPROND 109 RhesPD 109 RhesPD 112 GBA-PARK Probing Proteostasis in Neurodegenerative Disease using induced pluripotent stem cell-derived neuronal cultures Rhes protein and degeneration of nigrostriatal dopaminergic neurons: implications for Parkinson's Rhes protein and degeneration of nigrostriatal dopaminergic neurons: implications for Parkinson's GBA1 mutations in Parkinson s : clinical and biochemical prodrome, risk profile and pathogenetic modelling for therapeutic intervention. Consiglio Nazionale delle Ricerche Seconda Università degli Studi di Napoli (SUN) Dipartimento di Biol ogia e Biotecnologie Charles Darwin Institute for Polymers, Composites and Biomaterials - Catania Department of Environmental, Biological and Pharmaceutical Sciences and Technologies Università degli Studi di Cagliari (UNICA) Department of Biomedical Sciences Center for in (CRND) National Neurological Institute 112 GBA-PARK GBA1 mutations in Parkinson s : clinical and biochemical prodrome, risk profile and pathogenetic modelling for therapeutic intervention. University of Milan Department of Pharmacological Sciences

4 114 PRO-BRAIN 133 ENHANCE 134 CNS 136 SIMP-ADD 136 SIMP-ADD 139 REPEATOMIC 139 REPEATOMIC 140 IDEAs Protective lifestyle factors link brain and metabolism in preclinical and early stage Alzheimer s and Parkinson s : biomarkers and mechanisms of action. European ALS Network Harmonization, ANalysis and Cohort Enhancement Biomarkers for new therapeutic strategies in Alzheimer's Disease: neuroimaging studies. CIGARETTE SMOKE AND ELECTRONIC-CIGARETTE VAPOUR IMPACT ON ALZHEIMER S DISEASE DEVELOPMENT CIGARETTE SMOKE AND ELECTRONIC-CIGARETTE VAPOUR IMPACT ON ALZHEIMER S DISEASE DEVELOPMENT The role of tandem repeats in neurodegenerative s: the interaction of genomic and epigenomic markers The role of tandem repeats in neurodegenerative s: the interaction of genomic and epigenomic markers Identifying signatures of dementia in earlyonset patients using advanced genetic and -omics technologies Università degli Studi di Milano Department of Pharmaceutical Sciences University of Turin Department of Neuroscience University of Messina Università degli Studi di Modena e Reggio Emilia Department of Biological and Environmental Sciences University of Messina Department of Biomedical, Metabolic and Neural Sciences CNR Neuroscience Institute University of Eastern Piedmont CNR, The National Council Dept of Health Sciences, Interdisciplinary Center of Autoimmune Diseases Istituto di Tecnologie Biomediche - CNR (CNR-ITB) University of Brescia Neurology Unit, University of Brescia 146 PANDA Progress and Arrest of NeuroDegeneration in Aging Carlo Besta Institute, IRCCS foundation Division of neuropathology 150 Fast Fish 153 DeMentIA 156 ADAMD 161 PreventAGE A platform for rapid exploration of late onsetneurodegeneration in a naturally short-lived teleost fish HIV-brain infection and activation of innate immunity as a model of glia-mediated neurodegeneration Retinal pigment epithelium the window for early signs of Alzheimer s Influence of dietary AGEs in the physiopathology of Alzheimer`s Disease Scuola Normale Superiore Laboratory of Biology Ospedale San Raffaele (HSR) Department of Infectious Diseases University of Pavia Pharmacology Unit National Council Neuroscience Institute

5 161 PreventAGE 167 ALS-FTDcha 167 ALS-FTDcha 168 PARADE-AD Influence of dietary AGEs in the physiopathology of Alzheimer`s Disease Environmental challenge of animals and cells with familiar ALS mutations to model the human s ALS and/or FTD. Environmental challenge of animals and cells with familiar ALS mutations to model the human s ALS and/or FTD. Prevention of Alzheimer s through Diet and Exercise - understanding the mechanism Division of Neurology & InterUniversity, Second University of Naples Istituto Auxologico Italiano International Centre for Genetic Engineering and Biotechnology Department of Clinical and Experimental and Surgery Center for in Neuroscience Department of Neurology Stroke Unit and Neuroscience Laboratory. ICGEB University of Padua Department of Molecular 169 ModifAGE Modeling risk accumulation for non-healthy aging European Brain Institute European Brain Institute 173 CRELPD c-rel deficient mouse: an innovative animal model of Parkinson's University of Brescia Department of Molecular and 174 PRENEURO Synaptic and cognitive dysfunction in synucleinopathy: a step before neurodegeneration Dipartimento Scienze Biomediche, National Council (CNR) Institute of Genetics and Biophysics 176 SexInNeuro 178 SiDDHD Inflammatory and neuroprotective reactions to amyloid-β challenge by microglia and astrocytes: sex and nutritional relevancy Signatures of DNA Damage during Progression of Huntington Disease: Predictive and Precision University of Foggia Dept. of Clinical and Experimental Università degli Studi di Napoli DIpartimento di Biologia 178 SiDDHD Signatures of DNA Damage during Progression of Huntington Disease: Predictive and Precision Università degli Studi di Roma Centre for Experimental Neurological Therapies (CENTERS), Neurology and Department of Neurosciences, Mental Health and Sensory Organs (NESMOS) 9 BRAINCOFF Discovery of Alzheimer s risk and progression biomarkers associated to the protective effect of caffeine consumption University of Ferrara School of. Dept. Clinical and Experimental 75 TITRALS TIming and TRacking ALS (TITRALS): protective and modifying factors University of Bari Department of Basic Medical Sciences, Neurosciences and Sense Organs