CURRICULUM VITAE. Personal information. Education. Fields of interest. Alfred van Keulen.

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1 January, 2014 CURRICULUM VITAE Personal information Name: Alfred van Keulen. Education Pre-university training-b Graduation: May Institution: Hageveld College, Heemstede. Mechanical engineer (M.Sc.) Graduation: 29 April 1987 (cum laude). Institution: Delft University of Technology, Department of Mechanical Engineering, Engineering Mechanics Section. Training periods: ECN, Petten and DFVLR, Braunschweig, Germany. Endorsement: six-year course programme. Doctor of Philosophy in Technical Sciences (Ph.D.) Graduation: 26 January 1993 (cum laude). Institution: Delft University of Technology. Supervisor: Prof.dr.ir. J.F. Besseling. Title thesis: On Refined Triangular Plate and Shell Elements. HRM course ( Leergang 12 ) Human Resource Management for University Managers. Started in 1998, completed in Media Training April 5, 2005 Fields of interest Computational Mechanics and Structural Optimization, especially the application of these techniques to thin-walled structures and micro/nano devices and precision tools. 1

2 January, 2014 Professional experience Assistant professor at the Faculty of Mechanical Engineering and Marine Technology of Delft University of Technology Honorary visiting research fellow in Civil Engineering, University of Bradford Associate professor at the Faculty of Mechanical Engineering and Marine Technology of Delft University of Technology Deputy chairman Engineering Mechanics Section Part-time professor at the Faculty of Aerospace Engineering of Delft University of Technology Member of the Library Commission for the Faculty of Design, Engineering and Production present Personal professorship at the Faculty of Design Engineering and Production of Delft University of Technology (April 1, 1999) Visiting professor at University of Bradford (appointment for 3 years) Member of management team of Faculty 3ME Member of management team DIMES Chairman of the Department for Precision and Microsystems Engineering (roughly 100fte) Principal Investigator of MicroNed research program (total research budget 57MEuro, subsidy is 28MEuro) Scientific director of the Delft Research Centre for Mechatronics and Microsystems (roughly 100fte researchers) 2009 present Member of Executive Board Nanonextnl: FES High Tech Systems and Materials programme (Postive decision by Dutch Government on funding: Dec Total funding: 125MEuro. Total budget 250MEuro) Additional professional activities Librarian to the Engineering Mechanics section Secretary to the Engineering Mechanics section Co-founder and chairman DUSTOP (DUtch STructural OPtimization group). November 9, 1995 Symposium Structural Optimization in the Netherlands, at Delft University of Technology. Organization: dr.ir. F. van Keulen and dr.ir. A.J.G. Schoofs. March 13, 1997 Symposium Structural Optimization in the Netherlands, at Eindhoven University of Technology. 2

3 January, 2014 Organization: dr.ir. A.J.G. Schoofs and dr.ir. F. van Keulen Chairman of the Advisory Board on Information of the Faculty of Design, Engineering and Production MicroNano Congress in Delft, together with Prof Huub Salemink, +/-550 participants External examinor University of Limerick, Ierland Professional experience abroad: 1984 DFVLR, Braunschweig, Germany, 2 months ICNME, Barcelona, Spain, 1 week University of Bradford, Bradford, U.K., 2 months University of Bradford, Bradford, U.K., 6 weeks University of Wales, Swansea, U.K., 5 weeks University of Florida, USA, 2 months Department of Micro Engineering, Kyoto University, 2 months (Oct. Dec. 2007) 2008 Institute of Mechanical Systems, Department of Mechanical and Process Engineering, ETH Zurich, 6 months Research funds NWO-BC: MARC Zoetermeer: TUD: NWO-BC: Unilever FPU: NWO-BC: Van Leer R&D: 1994, JRP050, Dr.V.V. Toropov, Travelling grant, Optimization of geometrically nonlinear thin-walled structures based on FEM simulation and multi-point approximation techniques, 2x2 months. 1994, Adaptive Mesh Refinement, 12.5kf , Dr.A.A. Polynkine, Research fellow, Optimalisatie van met continue vezels versterkte thermoplastische produkten (Optimization of continuously fibre reinforced thermoplastic products), 1 year. 1995, JRP185, Dr.V.V. Toropov, Travelling grant, Development of structural optimization strategies which apply adaptive mesh refinement, 2x35 days , ir. R. van Dijk, Analyse van dunwandige verpakkingen (Analysis of thin-walled packages), 50kf. (Salary excluded) , JRP212, Prof. E. Hinton, Travelling grant, Combined shape and topology optimization with adaptivity, 2x35 days. 1996, ir. M. Klunne, Analyse van drums (Analysis of drums), 3

4 January, 2014 NWO: DLR, Stuttgart: TUD: TUD: Unilever FPU: TUD: TUD: TUD: DSM-Research: TUD: TUD: STW: TUD: EU: 30kf , Dr.A.A. Polynkine, Postdoc, Topology optimization of thin-walled structures using bubble methods and adaptivity, 1 year postdoc salary. Constitutive models for woven fabric reinforced thermoplastics, 1 Ph.D. student , Dr.V.V. Toropov, Visiting Professor, Structural Optimization, 6 months. 1996, Incentives Fund, Analyse en optimalisatie van dunwandige met continue vezels versterkte thermoplastische produkten (Analysis and optimization of thin-walled continuously fibre reinforced thermoplastic products), 35kf , ir. R. van Dijk, AIO, Optimalisatie en ontwerp van dunwandige verpakkingen welke worden geproduceerd m.b.v. blow-moulding (Optimization and design of thin-walled packages which are produced by means of blow-moulding), 440kf , Prof. Mukhopadhyay, Visiting Professor, Scheurgroei in scheepsconstructies (Crack growth in shipconstruction), 6 months, together with Marine Technology. 1999, Postdoc, Development and Application of Response Surfaces Using Design Sensitivities, 6 months postdoc salary , DIOC-program Development of Improved endoprostheses for the upper EXtremities (DIPEX). Program management: Stassen, Van der Helm and Van Keulen; ±4.5Mfl , Post-doctoral research fellowship: Utilization and improvement of an impregnation unit ; 260kfl. 2000, Postdoc, An investigation of the relationship between density, anisotropy and remodelling in trabecular bone in the glenoid region of the scapula, 12 months senior postdoc salary. 2001, Design of MEMS-based Catheters, 1 Ph.D. + associate professor. 2001, Joint project with Eindhoven University of Technology (Two Ph.D. s at TUE, one Ph.D. at DUT and one Ph.D. at DUT, but funded by Koiter Institute Delft) on: Sequential approximate design optimization including uncertainties, discontinuities and discrete design variables. Program leader: F. van Keulen. 2002, Collaboration with Erasmus University Rotterdam, 16kEuro. 2001, INTAS - International Association for the promotion of cooperation with scientists from the New Independent States of the former Soviet Union Project proposal no. 600: Experimental and numerical modelling of the response of damaged and undamaged masonry to static and dynamic loading Euro. 4

5 January, 2014 DFG-STW-NWO: Multiscale Methods in Computational Mechanics. Pre-proposal for a German - Dutch research group. (Ph.D position, ) Airbus: Fast reanalysis (Ph.D. position, together with Van Tooren en Rixen) ( ) Philips Semi cond.: Postdoc, 60k Euro. MicroNed (Initiator, chairman, total budget 56M, ICES-KIS3,later called FES): Model validation and experimental testing of multi-physical interactions in MEMS, , MicroNed, 301 k. Design optimization of a micro coriolis flow sensor, , Demcon, Bronckhorst,, 47 k. Advanced applications of topology optimization, , MicroNed, 128 k. Surface and Interface Effects, , 452 k. Multi-field design optimization of microsystem components, , 200k. Design optimization of reliable microsystem components, , MicroNed, PD-positions Nanonextnl (co-initiator, vice-chairman, total budget 250M, FES): Stability Calibration of Micro/Nano Cantilever structures, , NanoNextNl, 1241 k : 509k, MechWin, Nanosense Dynamics of Micro Nozzles in Large Arrays, k, Oce. Topology Optimization of Catalytic Microreactors for Energy Conversion and Storage, , Van Dijk FEM Engineering, 650 k. CRC: Design and optimization of wings for a flapping-wing micro air vehicle, , Chinese research council, 120 k EU: Control Designs for a Flapping Wing Micro Air Vehicle, , EU/Greece research council, 120 k, canceled. STW/NWO/DFG: International working group on Multiscale Methods in Computational Mechanics, exchange with Univ. of Stuttgart, Prof E. Ramm, travel budget, DRDC (Canada): Experimental and Numerical Modeling in support of a Structural Design Framework for Submarine Pressure Hulls, , PhD project. TNO: Robust Design Optimization for Integrated Photonic Systems, , STW, PhoeniX Software BV, LioniX, TNO, 770 k. STW: Valorisation grant, Commercialising the Electrostatic Pull-in Instability (EPI) calibration method, DELMES - 25k FOM/Shell: TopSol: Topology Optimization for Solar Panel Electrodes, , Shell-FOM, TNO, Shell, 230 k. Casimir/NWO: Atalanta, , Casimir/NWO, 278 k, DEVLAB member 5

6 January, 2014 companies. Point-One: Integral Optimization of Designs for Dynamics and Control Performance, , 646 k, Point-one, ASML, MI Partners Point-One: Regeling van resonante compliante systemen, , Pointone, DEVLAB member companies, 490 k. AgNL/Pieken in de Delta: Extreme Motion, Thermal Drift Models and Real-Time Compensations Strategies, 284k, , ASML, MIpartners. NIMR/M2I: Thin film micro-cavities for MEMS packaging, , PhD+PD postion. (PD not appointed), NXP, Philips. TNO: Massively paralleled 2D-array for scanning probe Instruments, 650k, 2 PhD, , TNO NLR: Topology optimization for aircraft movables, NLR, , 1 fully funded PhD researcher + 18k. International cooperation Dr. V.V. Toropov, University of Leeds, U.K. Prof. R.T. Haftka, University of Florida, U.S.A. Prof. I. Elishakov, Florida Atlantic University, U.S.A. Prof. P.J. Prendergast, Trinity College Dublin, Ireland Prof. U. Kirsch, Technion, Isreal Prof. E. Ramm, Stuttgart, Germany Prof Y.Y. Kim, SNU, Seoul, S. Korea Prof. O. Tabata, Kyoto, Japan Dr. M. Yamakawa, Kyoto, Japan Prof. K. Maute, University of Boulder, Co. Dr. J. MacKay, DRDC Prof. R.T, Haftka, UFL Dr. S. Venkataraman, SDSU, Ca. National cooperation ( DEVLAB Medical Faculty, Erasmus, Rotterdam. Leiden Medical Faculty. Dutch Space. TNO 6

7 January, 2014 NXP Philips Research ALE, Delft. Femto, Delft Van Dijk Engineering BV DSM Research. Airborne Development, Leidschendam Aquamarijn ASML OCE MI-Partners KMWE Participation in Engineering Mechanics Graduate School. Chair belongs to the Centre of Excellence Solids and Fluids University of Groningen DRDC Completed Ph.D. projects: Shape optimization of fabric reinforced products Design sensitivity analysis. H. de Boer, May 23, Optimization of thin-walled packaging. R. van Dijk, October 8, Stress Analysis of the Scapula Design Considerations of Glenoid Prostheses, March 5, (Supervisors: H.G. Stassen, F.C.T. van der Helm and F. van Keulen). Kinematics and stiffness of thermoformed plain-weave laminates Simple models and experimental validation, J. Hofstee, December 2, Performance Quantification and Simulation Optimization of Manufacturing Flow Lines. J.H. Jacobs (Defend, 13 September 2004, co-promotor at TU/e) Gradient-based Approximate Design Optimization, K.Vervenne, November 1th, Uncertainty-based Design Optimization of Structures with Bounded-but-Unknown Uncertainties, S. Gurav, December 13, Topology Optimization using a Topology Description Function Approach, M.J. de Ruiter, December 13, Simulation of Bone Ingrowth, A. Andreykiv, October 17, 2006 Design optimization of shape memory alloy structures, M. Langelaar, December 15, 2006 (Cum Laude) Micro-Electro-Mechanical Actuators Using Confined Polymers, Gih-Keoung Lau, December 5, A Graph-Based Optimization Method for the Design of Compliant Mechanisms and Structures, Michael Sauter, Co-promotor at ETH Zurich, May 15,

8 January, 2014 Distributed Optimization for Systems Design An Augmented Lagrangian Coordination Method, Simon Tosserams, Second promotor, TU/e, August 28,2008 A Study on Micro-gripping Technologies, Defeng Lang (Supervisors: F. van Keulen and M. Tichem), October 15, Development of a Rapid Thermoplastic Impregnation Device, Teun Weustink (Supervisors: F. van Keulen and R. Marissen), December 8, Wybren Jouwsma, Eredoctoraat, 9 jan 2009 A Unified Approach Towards Decomposition and Coordination for Multi-level Optimization, Albert de Wit, Nov. 30, 2009 Flapping wing actuation using resonant compliant mechanisms - An insect-inspired design, Casper Bolsman, 21 oct Mechanics of Ultra-sensitive Nanoelectromechanical Silicon Cantilevers - A Combined Experimental-Theoretical Approach, Hamed Sadeghian Marnani, 15 dec 2010 (Cum Laude). Mechanical Stability of Cementless Implants, The Glenoid Replacement, Daniel R. Suarez Venegas, 25 jan (Supervisors: Van Keulen, Rozing, Valstar) Experimental and Numerical Modeling in support of a Structural Design Framework for Submarine Pressure Hulls based on Nonlinear Finite Element Collapse Predictions, John R. MacKay, 28 june, 2012 Characterization of Thin Film MEMS Packages, Qian Li, 3 dec Pushing the Boundaries; Level-set Methods and Geometrical Nonlinearities in Structural Topology Optimization, Nico van Dijk, 23 Nov Research group (2014) Ph.D.students: +/- 13 (+ 2 vacancies) PostDoc(s): 1 Assistant profs: M. Langelaar, J.F.L. Goosen and 2 vacancies Part time researcher: Dr. H. Sadeghian lecturers: Wisse Final year students: +/-15 Boards and editorships Book review editor for Design Optimization, International Journal for Product & Process Improvement 1999 Session organizer for the 4th European Solid Mechanics Conference (ESMC4) 2000 Scientific committee of The Fifth International Conference on 8

9 January, 2014 Computational Structures Technology, 6 8 September, Second AIAA/ISSMO Internet Conference on Approximations and Fast Reanalysis in Engineering Optimization May 25 - June 2, Organizers: T. Baranger and F. van Keulen Book review editor for Structural and Multidisciplinary Optimization (Springer) Third AIAA/ISSMO Internet Conference on Approximations Optimization October 14 18, Organizers: R.T. Haftka and F. van Keulen Scientific committee of Euromech 442, Colloquium of Computer-Aided Optimization of Mechanical Systems, February 23 27, Scientific Committee WCSMO-5, May 19 23, Editorial Board CST2004: The Seventh International Conference on Computational Structures Technology, Lisbon, 7-9 September European Chair, 10th AIAA/ISSMO Multidisciplinary Optimization and Analysis Conference, Aug. 30 Sept. 1, 2004, Albany, New York Co-initiator of and member of board MinacNed Scientific Committee WCSMO Technical Committee Eurosime 2005, Berlin EPSRC review panel Scientific board of DevLab Member advisory council NanoNext research program Member of Academic Council of Point-One Scientific Committee WCSMO Assessment committee edicational program Advanced Technologies (Twente, Sept. 2007) 2008 EngOpt 2008, International Conference on Engineering Optimization, Rio de Janeiro, 2-5 June Scientific Committee WCSMO Executive board Nanonextnl (vice chair) 2010 Scientific Committee EngOpt Invited specialist at DEVLAB strategy meeting Member of NMP klankbord groep 2012 Review panel VUB Board member Holland Instrumentation Board member of Graduate School Engineering Mechanics 2013 Scientific Committee WCSM Assessment committee edicational program Advanced Technologies (Twente, Oct. 2013) 9

10 January, Program committee RapidPro Scientific Committee EngOpt Scientific Committee ASPE Spring Topical Meeting: Dimensional Accuracy and Surface Finish in Additive Manufacturing, April 2014, Berkeley Awards: Best poster award MicroMechanics Europe 2005: Actuated Elastomers with Rigid Vertical Electrodes, G.K. Lau, J.F.L. Goosen, F. van Keulen, P.M. Sarro. In-plane Thermal Unimorph Using Confined Polymers" has been awarded 1 of the 3 best posters in the MME 2006 at Southampton held on 3th-5th September Best poster presented at 20th MME 2009, Toulouse, France: On the Size-Dependent Elastic Behavior of Silicon Nanocantilevers, Sadeghian, H., C.K. Yang, J.F.L. Goosen, A. Bossche, U. Staufer, P.J. French, F. van Keulen Medal for the best poster of 5th International symposium on Surface science and Nanotechnology, 2008, Tokyo. Paper: "Effect of Surface stress on Nanocantilevers". Hamed Sadeghian et al. Most cited paper award (2009) for F. van Keulen, R.T. Haftka, N.H. Kim; Review of Options for Structural Design Sensitivity Analysis. Part1: Linear Systems, Comput. Methods Appli. Mech. Engrg. 194 (2005) IEEE CPMT Young Award 2008; Hermeticity and Thermal Stability Testing of PECVD Silicon Nitride Thin-Film Packages; Q. Li, J.F.L. Goosen, J.T.M. van Beek, F. van Keulen, K.L. Phan, B. van Velzen, J.J.M. Bontemps, J.J. Koning, G.Q. Zhang On the size-dependent elasticity of silicon nanocantilevers: impact of defects, Sadeghian et al., Journal of Physics D: Applied Physics, selected by the Editors for inclusion in the exclusieve 2011 Highlight collection Keynotes and invited talks (incomplete): 2005 Eurosim, Berlin 2006 Opening keynote, International Conference on MEMS and Nanotechnology (ICMN06) Kuala Lumpur, Malaysia March, Invited talk at ETHZ (Febr. 2008) 2008 Invited talk at San Diego state university (March 2008) 2008 Seminar at University of Dortmund (Nov. 2008) 2008 Invited seminar DRDC Halifax 2009 Keynote at Eurosim 2009 Invited seminar at UFL (nov. 2009) 10

11 January, Invited seminare at North Western (nov. 2009) 2009 Invited presentation at MEMS land symposium, Eindhoven 2010 Keynote at ASMO-UK, London, Invited seminar at Kyoto University, Tabata lab Invited talk at DEVLAB cafe 2011 Invited seminar at TNO Eindhoven 2012 Koiter lecture at EM symposium, Oct Invited presentation for NEVAT, Invited seminar at Uetani lab. Kyoto University 2013 Plenary panel speaker at WCSMO, May Invited speaker at NLR additive manufacturing symposium, Oct Invited presentation at Printing the City, Rotterdam, Nov

12 October 2013 LIST OF PUBLICATIONS Journal papers 1991: Bout, A., F. van Keulen, A mixed element for geometrically and physically nonlinear shell problems, Heron, Vol. 36, pp , 1991, ISSN: Keulen, F. van, A bound on the error in classical theory of laminated plates. Int. J.Engng Science, Vol. 29, No.7, pp , 1991, Pergamon Press. 1993: Keulen, F. van, A. Bout and L.J. Ernst, Nonlinear thin shell analysis using a curved triangular element. Comp. Meth. Appl. Mech. Engng. 103 (1993), pp Keulen, F. van, A geometrically nonlinear curved shell element with constant stress resultants. Comp. Meth. Appl. Mech. Engng. 106 (1993), pp : Polynkin, A.A., F. van Keulen and V.V. Toropov, Optimization of geometrically nonlinear thinwalled structures using the multipoint approximation method. Structural Optimization 9 (2), pp , : Keulen, F. van and J. Booij, Refined consistent formulation of a curved triangular finite rotation shell element, Int. J. Num. Meth. Engng. 39, , (1996). Polynkin, A.A., F. van Keulen and V.V. Toropov, Optimization of Geometrically Nonlinear Structures based on Multi-point Approximation Method and Adaptivity, Engineering Computations, 13, (2/3/4), pp , Polynkin, A.A., F. van Keulen, H. de Boer, O. K. Bergsma and A. Beukers, Shape optimization of thermoformed continuous fibre reinforced thermo-plastic products. Structural Optimization 11, , : Boer, H. de and F. van Keulen, Error Analysis of Refined Semi-Analytical Design Sensitivities, Structural Optimization, 14, 1997, Boer, H. de and F. van Keulen, Padé approximants applied to a nonlinear finite element solution strategy. Communications in Numerical Methods in Engineering, 13, pp , also pp , (1997). Keulen, F. van and V.V. Toropov, New Developments in Structural Optimization using Adaptive Mesh Refinement and Multi-Point Approximations, Eng. Opt., vol.29, 1997, Keulen, F. van, A. A. Polynkin and V. V. Toropov, Shape Optimization with Adaptive Mesh Refinement: Target Error Selection Strategies, Eng. Opt. 28, , (1997). 1998: Dijk, R. van, J.C. Sterk, D.Sgorbani and F. van Keulen; Lateral Deformation of Plastic Bottles: Experiments, Simulations and Prevention; Packag. Technol. Sci.11, (1998). Keulen, F. van and H. de Boer, Rigorous Improvement of Semi-Analytical Design Sensitivities by Exact Differentiation of Rigid Body Motions, Int. J. Numer. Meth.Engng. 42, (1998). 1999: 1

13 Dijk, R. van, F. van Keulen, J.C.Sterk; The influence of solubility effects on the pressure increase during deformation of closed thin-walled structures. Thin-walled structures , (1999). Keulen, F. van, and V.V. Toropov; The Multi-Point Approximation Method in a Parallel Computing Environment, ZAMM, 79 (S1), S67 S70, (1999). 2000: Boer, H. de, and F. van Keulen; Refined semi-analytical design sensitivities, Int. J. Solidsand Structures 37 (46 47), 2000, Dijk, R. van, F. van Keulen and J.C.Sterk; Simulation of closed thin-walled structures, Int. J. of Solids and Structures 37 (2000), Hofstee, J. and F. van Keulen; Elastic stiffness analysis of a thermo-formed plain weave fabric composite; Part II: analytical models, Composite Science and Technology, 60 (2000), Hofstee, J., H. de Boer and F. van Keulen; Elastic stiffness analysis of a thermoformed plain woven fabric composite; Part I: geometry, Composite Science and Technology, 60 (2000), : Dijk, R. van, H. de Boer and F. van Keulen; Accurate design sensitivities for closedfilled structures application to plastic bottles, Struct Multidisc Optim 21 (2001) 3, Hofstee, J. and F. van Keulen, 3-D geometric modeling of a draped woven fabric, Composite Structures 54 (2/3), , Vervenne, K., H. de Boer and F. van Keulen, Accuracy and implementation of refined second order semi-analytical design sensitivities; ZAMM, 81, Supplement 3, S699 S700, : Boer, H. de, F. van Keulen and K. Vervenne; Refined second order semi-analytical design sensitivities, Int. J. Num. Meth. Engng 2002, 55, Fatemi, J., F. van Keulen and P.R. Onck; Generalized Continuum Theories: Application to Stress Analysis in Bone. Meccanica 37, , Hofstee, J., H. de Boer and F. van Keulen, Elastic stiffness analysis of a thermoformed plainweave fabric composite: III Experimental verification, Composites Science & Technology, 62 (3), 2002, : Fatemi, J., P.R. Onck, G. Poort and F. van Keulen; Cosserat moduli of anistropic cancellous bone: a micromechanical analysis, J. Phys. IV France 105 (2003), Koppel, P.G.J. ten, J.M. van der Veen, D. Hein, F. van Keulen, G.J.V.M. van Osch, H.L. Verwoerd-Verhoef and C.D.A. Verwoerd; Controlling Incision-Induced Distortion of Nasal Septal Cartilage: A Model to Predict the Effect of Scoring of Rabbit Septa, Plast. Reconstr. Surg., 111 (6), , : Geris, L., A. Andreykiv, H. van Oosterwyck, J. Vander Sloten, F. van Keulen, J. Duyck and I. Naert; Numerical Simulation of Tissue Differentiation Around Loaded Titanium Implants in a Bone Chamber; Journal of Biomechanics, 37 (2004) Gupta, S., F.C.T van der Helm, J.C. Sterk, F. van Keulen and B.L. Kaptein; Development and experimental validation of a three-dimensional model of the human scapula, Proc. Instn. Mech. Engrs. Vol 218, Part H2: J. Engineering in Medicine, 2004,

14 Gupta, S., F.C.T. van der Helm, F. van Keulen; Stress Analysis of Cemented Glenoid Prostheses in Total Shoulder Arthroplasty, Journal of Biomechanics 37 (2004) Gupta, S., F.C.T. van der Helm, F. van Keulen; The Possibilities of Uncemented Glenoid Component a Finite Element Study, Clinical Biomechanics 19 (2004) Jacobs, J.H., L.F.P. Etman, F.van Keulen, and J.E. Rooda; Framework for sequential approximate optimization, Struct. Multidisc. Optim. 27, (2004). Keulen, F. van, and K. Vervenne; Gradient-Enhanced Response Surface Building,Struct. Multidisc. Optim. 27, , (2004). Langelaar, M. and F. van Keulen, A Simple R-phase Transformation Model for Engineering Purposes, Materials Science and Engineering: A - Structural Materials: Properties, Microstructure and Processing, 378 (1-2) pp , July Ruiter, M.J. de, and F. van Keulen; Topology Optimization using a Topology Description Function. Struct. Multidisc. Optim. 26, (2004). 2005: Andreykiv, A., P.J. Prendergast, F. van Keulen, W. Swieczkowski, P.M. Rozing; Bone Ingrowth Simulation for a Concept Glenoid Component Design. Journal of Biomechanics 38, , Goldfeld, Y., K. Vervenne, J. Arbocz and F. van Keulen; Multi-Fidelity Optimization of Laminated Conical Shells for Buckling, Struct. Multidisc Optim (2005) 30, Gurav, S., J. F. L. Goosen and F. van Keulen; Uncertainty-based design optimization using bounded-but-unknown design sensitivities and parallel computing: Application to MEMS. Computers and Structures, 83(14), , Keulen, F. van, R.T. Haftka, N.H. Kim; Review of Options for Structural Design Sensitivity Analysis. Part1: Linear Systems, Comput. Methods Appli. Mech. Engrg.194 (2005) Kirsch, U., M. Bogomolni and F. van Keulen; Efficient Finite-Difference Design Sensitivities; AIAA Journal, 43 (2), Febr. 2005, : Lau, G.K., J.F.L. Goosen, F. van Keulen, P.J. French and P.M. Sarro; Actuated Elastomers with Rigid Vertical Electrodes, J. Micromech. Microeng. 16 (2006), S35 S44. Moroni, Lorenzo, Gerard Poort, Fred van Keulen, Joost de Wijn and Clemens van Blitterswijk; Dynamic Mechanical Properties of 3D Fiber Deposited EOT/PBT Scaffolds: An Experimental and Numerical Analysis. Accepted for publication in Journal of Biomedical Materials Research: Part A, 2006, 78A (3), Schutte, S., S. P. W. van den Bedem, F. van Keulen, F. van der Helm, H. J. Simonsz, A finite element analysis model of orbital biomechanics, Vision Research, 46 (11), Spruijt, S., J.C. van der Linden, P.D.S. Dijkstra, T. Wiggers, M. Oudkerk, C.J. Snijders, F. van Keulen, J.A.N. Verhaar, H. Weinans, B.A. Swierstra; Prediction of torsional failure in 22 cadaver femora with and without simulated subtrochanteric metastatic defects - A CT scanbased finite element analysis; Acta Orthopaedica 2006; 77 (3): Yuan C, van Driel WD, van Silfhout RBR, van der Sluis O, Engelen RAB, Ernst LJ, van Keulen F, Zhang QG. (2006) Delamination analysis of Cu/low-k technology subjected to chemical-mechanical polishing process conditions, MicroElectronics Reliability, 46(9-11),

15 2007: Lau, G.K., T Chu Duc, J F L Goosen, F van Keulen, P M Sarro (2006) In-plane thermal unimorph using confined polymers, J. Micromech. Microeng. 17 (2007) S174 S183. Lau, G.K., J.F.L Goosen, F. van Keulen, T. Chu Duc, and P. M.Sarro; A powerful polymeric thermal micro-actuator with embedded silicon microstructure; Applied Physics Letters 90 (214103), 2007, p : Andreykiv, A., F. van Keulen and P.J. Prendergast, Computational Mechanobiology to Study the Effect of Surface Geometry on Peri-implant Tissue Differentiation. Journal of Biomechanical Engineering (ASME), October 2008, Andreykiv, A., Keulen, F. van, Prendergast, P.J.: Simulation of fracture healing incorporating mechanoregulation of tissue differentiation. In: Biomechanics and Modeling in Mechanobiology, Vol.7, No.6, p , Langelaar, M. and Van Keulen, F. (2008). Modeling of shape memory alloy shells for design optimization. Computers and Structures, 86(9): Langelaar, M. and Van Keulen, F. (2008). Sensitivity analysis of shape memory alloy shells. Computers and Structures, 86(9): Lau G.K., Goosen J.F.L., van Keulen F., Chu Duc T. Sarro P.M.; Polymeric Thermal Microactuator with Embedded Silicon Skeleton: Part 1 - Design and Analysis, J.Microelectromechanical Systems 17(4) , Lau G.K., Goosen J.F.L., Van Keulen F.; Thermoelastic Behavior of a Polymeric layer Bonded Between Rigid Interfaces, Int. J. Solids and Structures 45 (2008), Li, Q., J.F.L. Goosen, J.T.M. van Beek, F. van Keulen, K.L. Phan, G.Q. Zhang, Failure analysis of a thin-film nitride MEMS package, Journal Microelectronics Reliability 48 (2008), pp Yoon, G.H., Kim, Y.Y., Langelaar, M. and Van Keulen, F. (2008), Theoretical Aspects of the Internal Element Connectivity Parameterization Approach for Topology Optimization. International Journal of Numerical Methods in Engineering, 76(6): : Bolsman, C. T. and Goosen, J. F. L. and van Keulen, F.; Design Overview of a Resonant Wing Actuation Mechanism for Application in Flapping Wing MAVs,International Journal of Micro Air Vehicles, 2009,(1),4, pp Janssen, G.C.A.M., M.M. Abdalla, F. van Keulen, B.R. Pujada, B. van Venrooy; Celebrating the 100th anniversary of the Stoney equation for film stress: developments from polycrystalline steel strips to single crystal silicon wafers. Thin Solid Films, Volume 517, Issue 3, January 2009, Li, Qian, Hans Goosen, Fred van Keulen, Joost van Beek, Guoqi Zhang; Assessment of testing methodologies for thin-film vacuum MEMS packages; Microsyst Technol (2009) 15: Sadeghian H., J. F. L. Goosen, A. Bossche, F. van Keulen, Surface stress-induced change in overall elastic behavior and self-bending of ultra-thin cantilever plates. Applied Physics Letters. 94, , Sadeghian, H., C.K. Yang, K. Babaei Gavan, J.F.L. Goosen, E.W.J.M. van der Drift, H.S.J. van der Zant, P.J. French, A. Bossche, F. van Keulen, Effects of surface stress on nanocantilevers, E-Journal of Surface Science and Nanotechnology, 7, 2009, p

16 Sadeghian, Hamed, Chung-Kai Yang, Johannes Goosen, Emile Van der Drift, Andre Bossche, Patrick French, Fred van Keulen; Characterizing Size-dependent Effective Elastic Modulus of Silicon Nanocantilevers Using Electrostatic Pull-in Instability, Applied Physics Letters 94, , Selected for publication in Virtual Journal of Nanoscale Science and Technology, Vol. 19(24), Suarez D.R., Valstar E.R., van der Linden J.C., van Keulen F., Rozing P.M.; Effect of rotator cuff dysfunction on the initial mechanical stability of cementless glenoid components, Medical & Biological Engineering & Computing 2009 May; 47(5): Suarez, DR, JC van der Linden, ER Valstar, P Broomans, G Poort, F van Keulen, PM Rozing. Influence of cementless glenoid prosthesis positioning on its interface micromotions. Proceedings of the Institution of Mechanical Engineers, Part H, Journal of Engineering in Medicine, 2009 November; 223(7): : Dijk, N.P. van, Yoon, G.H., Van Keulen, A. and Langelaar, M. (2010). A level-set based topology optimization using the element connectivity parameterization method. Structural and Multidisciplinary Optimization 42(2): Lau, G.K., Goosen, J.F.L., van Keulen, F., Optimum Design of Polymeric Thermal Micro- Actuator with Embedded Silicon Skeleton. IEEE/ASME Journal of Microelectromechanical Systems, vol. 19, no. 4, august 2010, pp Li, Q., J.F.L. Goosen, J.T.M. van Beek and F. van Keulen; A SOI Pirani Sensor with Triple Heat Sinks; Sensors and Actuators A 162 (2010) MacKay, J.R., F van Keulen; A Review of External Pressure Testing Techniques for Shells including a Novel Volume-Control Method, Experimental Mechanics 2010, 50(6), Mackay, J.R., M.J. Smith, F. van Keulen, T.N. Bosman, N.G. Pegg; Experimental investigation of the strength and stability of submarine pressure hulls with and without artificial corrosion damage; Marine Structures 23 (2010), Sadeghian, H., J. F. L. Goosen, A. Bossche, Barend J. Thijsse, F. van Keulen, Surface reconstruction and elastic behavior of silicon nanobeams: The impact of applied deformation, Thin Solid Films 518 (2010), pp Sadeghian, H., J. F. L. Goosen, A. Bossche, F. van Keulen Application of electrostatic pull-in instability on sensing adsorbate stiffness in nanomechanical resonators, Thin Solid Films 518 (2010) Sadeghian, Hamed, Chung-Kai Yang, Hans Goosen, Andre Bossche, Paddy French, Fred van Keulen, Temperature Sensitivity of Silicon Cantilevers' Elasticity with the Electrostatic Pull-in Instability. Sensors and Actuators A 162 (2010) Sadeghian, Hamed, Chung-Kai Yang, J F L Goosen, A Bossche, Urs Staufer, P J French and Fred van Keulen,Effects of size and defects on the elasticity of silicon nanocantilevers, Journal of Micromechanics and Microengineering, Vol. 20, (2010) Sadeghian, Hamed, Chung-Kai Yang, Khashayar Babaei Gavan, Johannes F L Goosen, Emile W J M van der Drift, Herre S J van der Zant, Andre Bossche, Paddy J French and Fred van Keulen; Some considerations of effects-induced errors in resonant cantilevers with the laser deflection method;. Micromech. Microeng. 20, p , doi: / /20/10/105027, : Langelaar, M., Yoon, G.H., Kim, Y.Y. and Van Keulen, F. (2011). Topology optimization of planar shape memory alloy thermal actuators using Element Connectivity Parameterization. 5

17 International Journal for Numerical Methods in Engineering 2011;88: MacKay, John R., Fred van Keulen, Malcolm J. Smith; Quantifying the accuracy of numerical collapse predictions for the design of submarine pressure hulls; Thin-Walled Structures 49 (2011) MacKay, John R., Lei Jiang, Andre H. Glas, Accuracy of nonlinear finite element collapse predictions for submarine pressure hulls with and without artificial corrosion damage. Marine Structures, 24, 2011, p Sadeghian, Hamed, Hans Goosen, Andre Bossche, Barend Thijsse and Fred van Keulen; On the size-dependent elasticity of silicon nanocantilevers: impact of defects; J. Phys. D: Appl. Phys. 44 (2011), p (6pp). Sadeghian, Hamed, Johannes F.L. Goosen a, Andre Bossche b, Barend J. Thijsse c, Fred van Keulen; Effects of size and surface on the elasticity of silicon nanoplates: Molecular dynamics and semi-continuum approaches; Thin Solid Films 520 (2011) : Andreykiv, A., F. van Keulen, D. J. Rixen, E. Valstar A level-set-based large sliding contact algorithm for easy analysis of implant positioning. Int. J. for Numerical Methods in Engineering 89(10) (2012). Dijk, N.P. van, M. Langelaar, F. van Keulen; Explicit level-set-based topology optimization using an exact Heaviside function and consistent sensitivity analysis, Int.Int. J. Numer. Meth. Engng 2012; 91:67 97, MacKay, J.R., M.J. Smith, F. van Keulen and T.N. Bosman; Experimental study of the interaction of corrosion damage and out-of-circularity in the collapse of submarine pressure hulls. Trans RINA, Vol 154. Part A3, Intl. J. Maritime Eng. Jul. Sep. 2012, A-157 A-168. Suarez, D.R., H. Weinans, F. van Keulen; Bone remodelling around a cementless glenoid component; Biomech Model Mechanobiol (2012) 11: Suárez, Daniel R. ; Willem Nerkens; Edward R Valstar ; Piet M Rozing; Fred van Keulen; Interface micromotions increase with less conforming cementless glenoid components; Journal of Shoulder and Elbow Surgery, 21(4), (2012). Williams, M.D., F. van Keulen, and M. Sheplak; Modeling of Initially Curved Beam Structures for Design of Multistable MEMS, Journal of Applied Mechanics, JANUARY 2012, Vol. 79 / : Dijk, N.P. van, K. Maute M. Langelaar F. van Keulen; Level-set methods for structural topology optimization: a review; Struct Multidisc Optim DOI / s y, 2013 (online available). MacKay, J.R. and F. van Keulen; Partial safety factor approach to the design of submarine pressure hulls using nonlinear finite element analysis; Finite Elements in Analysis and Design 65 (2013) Rehman, S. ur, Langelaar, M., & Van Keulen, F. (2013). Robust optimization of 2x2 multimode interference couplers with fabrication uncertainties, doi: / Suarez, Daniel R., Edward R Valstar, Piet M Rozing and Fred van Keulen; Fracture risk and initial fixation of a cementless glenoid implant: The effect of numbers and types of screws; In: Proc IMechE Part H: J Engineering in Medicine 0(0) 1 9 IMechE 2013 DOI: /

18 Books/chapters in books Bout, A., F. van Keulen, A mixed geometrically nonlinear shell element, In: Integration of Theory and Applications in Applied Mechanics, Eds. J.F. Dijksman and F.T.M. Nieuwstadt, pp , Kluwer Keulen, F. van, A finite rotation triangular shell element, In: Topics of Applied Mechanics, Eds. J.F. Dijksman and F.T.M. Nieuwstadt, pp , Kluwer Keulen, F. van, On refined triangular plate and shell elements, Thesis, TU-Delft 1993, ISBN Boer, H. de, Van Keulen, F. and Wever, R. An Optimization Based Method for Simulation of Forming Processes of Woven Fabric Reinforced Composites, In: Simulation of Materials Processing: Theory, Methods and Applications, J. Huetink and F.P.T. Baaijens (eds), Balkema, Rotterdam, ISBN X, pp , (1998). Dijk, R. van, and F. van Keulen; A Finite Rotation Shell Element Taking into account Pneumatic Effects, In: S.N. Atluri and P.E. O Donoghue, Modeling and simulation based engineering, Vol I, , Tech Science Press, Palmdale, Bergsma, O.K., F. van Keulen, A. Beukers, H. de Boer and A.A. Polynkine; 3-D Forming of Continuous Fibre Reinforcements for Composites. In: A. Miravete (Ed.); 3-D Textile Reinforcements in Composite Materials, Woodhead Publishing Limited, Cambridge England, ISBN , pp (1999). Ruiter, M.J. de, and F. van Keulen; Topology optimization: approaching the material distribution problem using a topological function description, In B.H.V. Topping (ed.), Computational Techniques for Materials, Composites and Composites Structures, Civil-Comp Press, Edinburgh, 2000, , ISBN Vermolen, F.J., A. Andreykiv, E.M. van Aken, J.C. van der Linden, E. Javierre, and A. van Keulen; A Suite of Mathematical Models for Bone Ingrowth, Bone Fracture Healing and Intra- Osseous Wound Healing; In: B. Koren and C. Vuiks (eds.), Advanced Computational Methods in Science and Engineering, Lecture Notes in Computational Science and Engineering 71, Springer-Verlag Berlin Heidelberg, 2010, pp Wit, A. de and F. van Keulen; Framework for Multi-Level Optimization of Complex Systems; In: Multiscale Methods in Computational Mechanics, Progress and Accomplishments, R. de Borst and E. Ramm eds. Springer 2011, ISBN , pp Sadeghian, Hamed, Fred van Keulen and Hans Goosen; Mechanics of NanoelectromechanicalSystems: Bridging the Gap between Experiment and Theory; In: Advances in Micro/Nano Electromechanical Systems and Fabrication Technologies, ISBN , edited by Kenichi Takahata ; available online: Sadeghian, Hamed, Fred van Keulen and Hans Goosen; Mechanics of Nanoelectromechanical Systems: Bridging he Gap between Experiment and Theory; In: Advances in Micro/Nano Electromechanical Systems and Fabrication Technologies, ISBN , edited by Kenichi Takahata ; available online: Conference proceedings 1994: Booij, J. and F. van Keulen, Consistent formulation of a triangular finite rotation shell element, 7

19 Proceedings of the first International DIANA Conference on Computational Mechanics, In: DIANA Computational Mechanics 94, Eds. G.M.A. Kusters and M.A.N. Hendriks, pp , Kluwer Keulen, F. van, V.V. Toropov and A.A. Polynkine, Optimization of geometrically nonlinear shell structures using adaptivity, Proceedings of Fifth AIAA/USAF/NASA/ISSMO Symposium, AIAA , pp , : Keulen, F. van, V. V. Toropov and A. A. Polynkine, Shape optimization strategies using the multi-point approximation method and adaptive mesh refinement. In: N.Olhoff and G.I.N. Rozvany (eds.), WCSMO-1, First World Congress of Structural and Multidisciplinary Optimization, Pergamon, pp , : Boer, H. de, and F. van Keulen, Padé approximants applied to a nonlinear finite element solution strategy. In: J.A.Désidéri et al. eds., Numerical Methods in Engineering 96, Proceedings of the Second ECCOMAS Conference on Numerical Methods in Engineering, 9 13 September, 1996, Paris, France, John Wiley & Sons, Ltd.1996, pp , ISBN Keulen, F. van, and E. Hinton, Topology design of plate and shell structures using the hard kill method, in Advances in structural Engineering Optimization (ed. B.H.V. Topping), pp , Civil Comp. Press, Edinburgh, presented at the Third International Conference in Computational Structural Technology in Budapest, August, 1996, ISBN Keulen, F. van, V. Toropov and V. Markine, Recent refinements in the multi-point approximation method in conjunction with adaptive mesh refinement, In: J.M. Mc-Carthy (ed.), Proceedings of The 1996 ASME Design Engineering Technical Conferences and Computers in Engineering Conference, August 18 22, Irvine California, 96-DETC/DAC-1451, 12p., ISBN Toropov, V.V., F. van Keulen, V. Markine and H. de Boer, Refinements in the Multipoint Approximation Method to Reduce the Effects of Noisy Structural Responses. In: 6th AIAA/NASA/ISSMO Symposium on Multidisciplinary Analysis and Optimization, Bellevue WA, September 4 6, 1996, Part 2, A Collection of Technical Papers, AIAA CP, pp , ISBN X. 1997: Boer, H. de, and F. van Keulen; Improved Semi-Analytic Design Sensitivities for a Linear and Finite Rotation Shell Element; In: W. Gutkowski and Z. Mróz (eds.), WCSMO-2, Second World Congress of Structural and Multidisciplinary Optimization, 1997, pp , ISBN : Boer, H. de, F. van Keulen and R. Wever; Simulating forming processes of fabric reinforced composites by applying optimization, AIAA , In: 7th AIAA/USAF/NASA/ISSMO Symposium on Multidisciplinary Analysis and Optimization, St. Louis, Missouri, September 2 4, 1998, Part 2, p ,(1998). Hofstee, J., F. van Keulen, H. de Boer and K. Stellbrink; Stiffness Analysis of Thermoformed Plain Weave Composites, In: I. Crivelli-Visconti, ECCM-8 European Conference on Composite Materials, Science, Technologies and Applications, 3-6 june 1998, Naples, Italy, Volume 2, pp , Woodhead Publishing Ltd., Abington, England, ISBN Keulen, F. van, and H. de Boer, H.; Refined semi-analytical design sensitivities for buckling, AIAA , In: 7th AIAA/USAF/NASA/ISSMO Symposium on Multidisciplinary Analysis and Optimization, St. Louis, Missouri, September 2 4, 1998, Part 1, p , (1998). Keulen, F. van, and H. de Boer; Accurate Design Sensitivities for Deployable Structures by 8

20 Exact Differentiation of Rigid Body Modes. In: S. Pellegrino and S. D. Guest (eds.) IUTAM- IASS Symposium on Deployable Structures: Theory and Applications; Cambridge, UK, 6-9 September 1998, August 2000, Kluwer Academic Publishers, Dordrecht pp Keulen, F. van, and V.V. Toropov; Multipoint Approximations for Structural Optimization Problems with Noisy Response Functions; ISSMO/NASA/AIAA First Internet Conference on Approximations and Fast Reanalysis in Engineering Optimization, June 14 27, 1998 (CD- ROM). 1999: Boer, H. de, and F. van Keulen; Design sensitivities for optimization based forming simulation; In: V.V. Toropov (ed.) Engineering Design Optimization, Proceedings of 1st, ASMO UK /ISSMO conference, 8 9 July, Ilkley, UK, MCB University Press, Bradford, UK, pp , (1999). Boer, H. de, and F. van Keulen; Refined second order semi-analytical design sensitivities. Proceedings of the Third World Congress of Structural and Multidisciplinary Optimization, May 17 21, 1999, Buffalo, New York, CD-ROM (Paper 12-SAM-4). Dijk, R. van, and F. van Keulen; Optimization of plastic packaging; In: V.V. Toropov (ed.) Engineering Design Optimization, Proceedings of 1st, ASMO UK /ISSMO conference, 8 9 July, Ilkley, UK, MCB University Press, Bradford, UK, pp , (1999). Dijk, R. van, and F. van Keulen; Simulation of Closed-Filled Structures; Permeability, Solubility and Chemical Reactions. In: W. Wunderlich, Proceedings of the European Conference on Computational Mechanics (ECCM 99) August 31 September 3, 1999, Munich Germany, 19 pages. Dijk, R. van, H. de Boer and F. van Keulen; Accurate design sensitivities for closed filled structures. Proceedings of the Third World Congress of Structural and Multidisciplinary Optimization, May 17 21, 1999, Buffalo, New York, CD-ROM (Paper 47-SAA-3). Hofstee, J. and F. van Keulen; The effect of simple shear on stiffness and strength of fabric laminates, In: T. Massard, Proceedings of the Twelfth International Conference on Composite Materials, Paris, July 5 9, 1999 (CD-ROM) also LTM 1199, Toropov, V.V., F. van Keulen, V.L. Markine and L.F. Alvarez; Multipoint approximations based on response surface fitting: a summary of recent results; In: V.V. Toropov (ed.) Engineering Design Optimization, Proceedings of 1st, ASMO UK /ISSMO conference, 8 9 July, Ilkley, UK, MCB University Press, Bradford, UK, pp , (1999). 2000: Dijk, R. van, and F. van Keulen; Deformation of Closed-Filled Packages due to Oxidation, Permeation and Solubility Effects; Proceedings of the IASS-IACM 2000, Fourth International Colloquium on Computation of Shell & Spatial Structures, Eds. M. Papadrakakis, A. Samartin and E. Onate, June 5-7, 2000, Chania-Crete, Greece (LTM-1228, 14 pages). Dijk, R. van, and F. van Keulen; Optimization of food packaging; explorative study to the optimal bottle design (Part 1). Proceedings of the European Congress on Computational Methods in Applied Sciences and Engineering, ECCOMAS 2000, Barcelona, September CD-ROM Proceedings: ISBN Hofstee, J. and F. van Keulen, 3-D geometric modeling of a draped woven fabric, In: S. Adali, E.V. Morozov and V.E. Verijenko (eds.), Proc. 3rd Int. Conf. Composites Science and Technology (ICCST/3), Durban, S.A., January Pages (ISBN ) Hofstee, J. and F. van Keulen; Effects of geometry deviations on mechanical properties of a plain woven fabric lamina, In: A.G. Gibson (Ed.) Proceedings of the 8 th International Conference on Fibre Reinforced Composites, FRC 2000, Newcastle, U.K September, 9

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