Neuro-Urology Spinal Cord Injury Center & Research University of Zurich

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1 Curriculum vitae CV Ulrich Mehnert Name First name(s) Contact Mehnert Ulrich Professional: Neuro-Urology Spinal Cord Injury Center & Research University of Zurich Balgrist University Hospital Forchstrasse 340, 8008 Zurich Switzerland Tel.: (office) (mobile) Fax: Education 08/ / 1997 Gymnasium Lünen-Altlünen (Lünen, North Rhine-Westphalia, Germany): School education and graduation with general qualification for university entrance (A-levels). 10/ / 2004 Medical School at the University of Ulm (Ulm, Baden-Württemberg, Germany): Studies in human medicine, including several one to four months clinical electives at home and abroad. Clinical / professional experiences 12/ / 2005 Texas Heart Institute (Houston, Texas, USA): Internship for 8 weeks in cardiovascular surgery (Head of Institute: Prof. Dr. Denton A. Cooley) / 2005 Yale-New Haven Hospital, Yale University (New Haven, Connecticut, USA): Internship for 4 weeks in the Department of Urology (Head of Department: Prof. Dr. Robert M. Weiss) and for 4 weeks in the Department of Plastic and Reconstructive Surgery (Head of Department: Prof. Dr. John A. Persing). 07/ / 2006 University Hospital Schleswig-Holstein, Campus Kiel (Kiel, Schleswig- Holstein, Germany): Urologist-in-training in the Department of Urology and Paediatric Urology (Head of Department: Prof. Dr. K.-P. Jünemann). 01/ / 2009 Spinal Cord Injury Center & Research, University of Zurich, Balgrist University Hospital (Zurich, Zurich, Switzerland): Urologist-in-training in Neuro-Urology (Head of Section : Prof. Dr. Brigitte Schurch) and postdoctoral research fellow in Neuro-Urology Research. Since 09/ 2009 Spinal Cord Injury Center & Research, University of Zurich, Balgrist University Hospital (Zurich, Zurich, Switzerland): Project leader and coordinator in Neuro-Urology Research. 11/ / 2010 University Hospital Pitié-Salpêtrière (Paris, France): Clinical fellowship in the Department of Urology and Renal Transplantation (Head of Department: Prof. Dr. Marc Olivier Bitker) with special emphasis on training in Neuro-Urology by Prof. Dr. Emmanuel Chartier-Kastler. Page 1 of 5

2 01/ / 2014 Marienhospital Herne, Ruhr University Bochum (Herne, Germany): Urologist-in-training in the Department of Urology and Neuro-Urology (Head of Department: Prof. Dr. Joachim Noldus) From 07/ 2014 Spinal Cord Injury Center & Research, University of Zurich, Balgrist University Hospital (Zurich, Zurich, Switzerland): Consultant urologist in Neuro-Urology (Head of Section since 2010: PD Dr. Thomas M. Kessler) and Project leader in Neuro-Urology Research. Diploma / Degrees 08/ 2000 German preclinical medical state examination 08/ 2001 German medical state examination step 1 08/ 2003 German medical state examination step 2 03/ 2004 United States Medical Licensing Examination (USMLE) Step 1 11/ 2004 German medical state examination step 3 11/ 2004 Licence to practice medicine 04/ 2005 Doctoral dissertation defence at the University of Ulm and granting of the Medical Doctor (M.D.) degree 01/ 2014 Board certification as urologist / specialist in urology Dissertation 02/ / 2005 Original title Biomechanische!n-vitro Untersuchung von Kypho- und Vertebroplastie mit CaP- und PMMA-Zement Supervisor Institution Defence date Grading Publication Prof. Dr. Hans-Joachim Wilke Institute of Orthopaedic Research and Biomechanics at the University of Ulm (Ulm, Baden-Württemberg, Germany) magna cum laude Wilke, H. J., Mehnert, U., Claes, L. E., Bierschneider, M. M., Jaksche, H., Boszczyk, B. M.: Biomechanical evaluation of vertebroplasty and kyphoplasty with polymethyl methacrylate or calcium phosphate cement under cyclic loading. Spine, 31: 2934, 2006 Skills / Qualifications Languages: German native language English fluent in spoken and written Page 2 of 5

3 French good knowledge and continuous further education CV Ulrich Mehnert Advanced training in: Reviewer for: Good Clinical Practice (GCP) for investigators and study coordinators Academic didactics Radiation Protection BJU international, Case Reports in Medicine, Clinical Autonomic Research, Computer Methods and Programs in Biomedicine, European Journal of Neurology, European Urology, Neurourology and Urodynamics, The Journal of Urology, World Journal of Urology Scientific Interests / Main Research Activities Neuro-Urology, in specific: - Neurophysiology of the human lower urinary tract - Pathogenesis of lower urinary tract dysfunctions - Urodynamics and the evaluation as well as modulation of lower urinary tract sensations (e.g. desire to void) - Spinal and supraspinal neuronal control of the human lower urinary tract - Functional neuroimaging of supraspinal lower urinary tract control - Conservative and surgical therapy of lower urinary tract dysfunctions Teaching experience Regular biannual internal and external educational lectures for nursing staff in the field of urological and neuro-urological patient management Since 02/ 2013 Lecturer at the medical faculty of the University of Zurich for the following semester courses/modules: - Aktuelle Probleme der Paraplegiologie (1h) - Forschungsseminar Paraplegiologie (1h) - Einführung in die klinische Neuro-Urologie bei spinalen Erkrankungen (1h) - Interdisziplinäre Fallbesprechung Paraplegiologie (1h) - Klinische und neurophysiologische Einführung in die Paraplegiologie (1h) Collaborations (national) Since 2006 Department of Neuroradiology (Prof. Dr. Spyros Kollias, Dr. Lars Michels), University Hospital Zurich: joint research projects, knowledge transfer, infrastructure Page 3 of 5

4 Since 2007 Since 2013 Department of Urology (Prof. Dr. Tullio Sulser, PD Dr. Daniel Max Schmid), Department of Gynecology (Prof. Dr. Daniel Fink, Dr. David Scheiner), and Department of Neurology (Prof. Dr. Michael Weller, PD Dr. Michael Linnebank), University Hospital Zurich: joint research projects, knowledge transfer, infrastructure Department of Clinical Neurosciences, Service of Neuropsychology and Neurorehabilitation (Prof. Dr. Brigitte Schurch), University Hospital Centre (CHUV), University of Lausanne: knowledge transfer Collaborations (international) Since 2010 Since 2012 Since 2013 Department of Uro-Neurology (Dr. Jalesh Panicker), National Hospital for Neurology and Neurosurgery, University College London, UK: joint research projects, knowledge transfer, exchange of PhD students Department of Urology (Prof. Dr. Philip van Kerrebroeck), University Hospital Maastricht, University of Maastricht, the Netherlands: knowledge transfer, exchange of PhD students Department of Urology (Prof. Dr. Stefan de Wachter), University Hospital Antwerp, University of Antwerp, Belgium: knowledge transfer, exchange of PhD students Memberships Since 2006 Since 2009 Since 2010 Since 2011 Since 2011 EAU European Association of Urology ICS International Continence Society Forum Urodynamicum Swiss Continence Foundation (Vice-Chairman) DGU Deutsche Gesellschaft für Urologie Prices / Awards 03/ 2008 Price for Best Poster Presentation in a Poster Session during the 23 rd Annual EAU Congress in Milan. 03/ 2009 Eugen-Rehfisch-Prize for the best scientific work in applied clinical research, awarded at the 20 th Annual Meeting of the Forum Urodynamicum 2009 in Kassel / Bad Wildungen. 03/ 2009 Price for Best Poster Presentation in a Poster Session during the 24 th Annual EAU Congress in Stockholm. 03/ 2012 Eugen-Rehfisch-Prize for the best scientific work in applied clinical research, awarded at the 23 rd Annual Meeting of the Forum Urodynamicum 2012 in Zurich. Page 4 of 5

5 Research Grants (as principal investigator) 10/ / 2012 Swiss National Science Foundation (SNF 32003B_127477): Evaluation of new approaches in the treatment and neurophysiological assessment of healthy and impaired human lower urinary tract function 375, CHF 12/ / 2014 Swiss National Science Foundation (SNF 32003B_135774): The bladder and the brain - supraspinal control of lower urinary tract function in patients with neurogenic and non-neurogenic bladder dysfunction 375, CHF 06/ / 2014 SwissLife Jubiläumsstiftung: Die Blase und das Gehirn Untersuchung der supraspinalen Steuerung des unteren Harntraktes bei Patienten mit neurogener und nicht-neurogener Harnblasenfunktionsstörung 32, CHF 10/ / 2016 Swiss National Science Foundation (SNF 32003B_149628): Evaluation of new approaches in the treatment and neurophysiological assessment of healthy and impaired human lower urinary tract function II 320, CHF Research Grants (as co-investigator) 04/ / 2008 Pfizer Ltd., A : Evaluation of Sympathetic Skin Response and Heart Rate Variability as Objective Measures of Bladder Sensation a Double-Blind, Placebo Controlled, Randomised Study using a Single Dose of Tolterodine (8mg ER) in Patients with Idiopathic Overactive Bladder and Healthy Volunteers 135, CHF 07/ / 2014 Wings for Life Spinal Cord Research Foundation: Neurogenic detrusor overactivity due to sponal cord injury and botulinum neurotoxin A injections into the detrusor: A structural and functional magnetic resonance imaging study on supraspinal lower urinary tract control. 74, EUR Zürich, Ort und Datum Unterschrift Page 5 of 5