Department of Biomedical Engineering

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1 The University of Texas at San Antonio Department of Biomedical The Department of Biomedical offers a Bachelor of Science degree in Biomedical. Bachelor of Science Degree in Biomedical A Bachelor of Science (B.S.) degree in Biomedical (BME) at UTSA is an interdisciplinary program that combines engineering principles, approaches, and methodologies with biological, chemical and physical sciences in order to define and solve problems in medicine. Students will be trained in the fundamentals of science and engineering and are expected to be able to apply this knowledge to investigate fundamental biomedical engineering questions associated with complex living systems as well as with the diagnosis and treatment of human diseases. A broad understanding of sciences and engineering principles is provided in the first two years of the program, with students having the option to choose one concentration as in-depth focus areas of study in the last two years of the program. Critical thinking and innovative design skills are integrated throughout the program to aid students in developing solutions and in solving biomedical engineering-related problems. Design projects throughout the program and Senior BME Design courses provide students the opportunity to integrate their design, critical thinking and communication skills with the scientific and engineering knowledge they acquired throughout the Biomedical program. The regulations for this degree comply with the general University regulations (refer to Bachelor s Degree Regulations ( Admission Requirements A first-time, full-time freshman admitted as a biomedical engineering major must meet the minimum admission criteria of the College of. These criteria are: Students must meet all UTSA admission requirements; Students must have credit for MAT 24 Calculus I or have completed all necessary prerequisites to enroll in MAT 24 (through a mathematics placement test or credit for MAT 09 Precalculus or an equivalent). Students must:. have graduated in the top quartile of their high school graduation class, or 2. have graduated in the second quartile of their high school class and have a combined SAT critical reading and mathematics score of at least 00 with a minimum mathematics score of 550, or an ACT composite score of at least 24, or. be granted admission into a College of major by holistic review by the College of if not meeting the criteria in and 2 above. All students applying for admission to the Biomedical program must submit the following supplemental documents to the Department of Biomedical : two (2) letters of recommendation, a copy of the transcript, and a statement of their interests, professional career goals and how the Biomedical program will help them achieve those goals. All transfer students must meet the aforementioned minimum admission requirements for the College of and the Biomedical program. Transfer students must also meet the minimum Good Academic Standing Requirements for a Biomedical Major (see below) in order to be considered for admission to the Biomedical program. Additionally, transfer students should also have completed at least 5 semester credit hours of mathematics, science, or engineering courses, and have an overall grade point average of a.0 or better. Admissions to the biomedical engineering program will be competitive; meeting the aforementioned requirements does not guarantee admission to the program. Admission will be restricted only to the most qualified applicants. Good Academic Standing Requirements for a Biomedical Major All students must be in good academic standing in order to remain in the Biomedical program. The minimum requirements that a student must satisfy in order to remain in good standing as a biomedical engineering major are stated below: A cumulative grade point average (GPA) of at least.0 for all coursework (cumulative GPA will be calculated on all courses, including previously attempted or repeated courses). An average GPA of at least.0 for all science, mathematics and engineering coursework (GPA will be calculated on all courses, including previously attempted or repeated courses). Students who fail to meet the above requirements but have a minimum cumulative GPA of 2.5 or above will be placed on programmatic probation in the following semester. Students who fail to maintain good academic standing after a semester of programmatic probation or who have a cumulative GPA below 2.5 will be deemed to be not in good academic standing as a biomedical engineering major and will be removed from the program. Education Objectives The objectives of this program are founded on the belief that engineering principles and understanding of biological and physical sciences are critical to the investigation of fundamental bioengineering questions associated with complex living systems as well as with the diagnosis and treatment of human diseases. As such, the program educational objectives of the UTSA Biomedical program are to prepare graduates who will be able to: contribute positively to the biomedical industries and/or other sectors such as hospitals, government agencies, and academia; enhance competence in biomedical engineering by pursuing an advanced or a professional degree; and work successfully as a member in a team environment to facilitate biomedical engineering practice. The minimum number of semester credit hours required for this degree is 25, at least 9 of which must be at the upper-division level. All candidates for this degree must fulfill the Core Curriculum requirements, the General requirements, and the degree requirements, listed below.

2 Department of Biomedical Core Curriculum Requirements (42 semester credit hours) Students seeking the Bachelor of Science degree in Biomedical must fulfill the University Core Curriculum requirements in the same manner as other students. The courses listed below satisfy both major requirements and Core Curriculum requirements; however, if these courses are taken to satisfy both requirements, then students may need to take additional courses in order to meet the minimum number of semester credit hours required for the degree. MAT 24 may be used to satisfy the core requirement in Mathematics, as well as one of the General Requirements. BIO 404 and PHY 94 may be used to satisfy the core requirement in Life and Physical Sciences, as well as one of the General Requirements. Core Curriculum Component Area Requirements ( catalog.utsa.edu/undergraduate/bachelorsdegreeregulations/ degreerequirements/corecurriculumcomponentarearequirements) First Year Experience Requirement Communication 6 Mathematics Life and Physical Sciences 6 Language, Philosophy and Culture Creative Arts American History 6 Government-Political Science 6 Social and Behavioral Sciences Component Area Option Total Credit Hours 42 General Requirements All degree-seeking candidates in engineering must complete the following 22 semester credit hours, as well as the Core Curriculum requirements and major requirements: CHE 0 General Chemistry I EGR 22 Applied Analysis I MAT 24 Calculus I 4 MAT 224 Calculus II 4 or EGR 24 PHY 94 & PHY 95 PHY 96 & PHY 97 Calculus II for Engineers Engineers I and Engineers I Laboratory Engineers II and Engineers II Laboratory Total Credit Hours 22 Gateway Course Students pursuing the Bachelor of Science degree in Biomedical must successfully complete the following Gateway Course with a grade of C- or better in no more than two attempts. A student who is unable to successfully complete this courses within two attempts, including dropping the course with a grade of W or taking an equivalent course at another institution, will be required to change his or her major. 4 4 EGR 22 Applied Analysis I Biomedical Requirements A. Core Biomedical Requirements All students majoring in Biomedical are required to complete 6 semester credit hours in the following Core Biomedical courses. BME 002 Introduction to Biomedical 2 BME 20 Physiology for Biomedical BME 220 Biomechanics I BME 00 Biomaterials I BME 0 Clinical Internship in Biomedical BME 022 Biomedical Technology and Product Development BME 4 Cellular Biology for Biomedical 4 BME 2 Biomedical Laboratory I BME 0 Bioinstrumentation BME Biomedical Laboratory II BME 70 Biotransport Phenomena BME 7 Biomedical Laboratory III BME 490 Senior BME Design I BME 49 Senior BME Design II B. Other Required Courses All students majoring in Biomedical are required to complete 6 semester credit hours in the following: CHE General Chemistry II STA 40 Probability and Statistics for the Biosciences C. Biomedical Electives A minimum of 5 semester credit hours is required to fulfill this requirement. 9 semester credit hours of Biomedical elective courses must be selected from one of the following concentrations. The remaining semester credit hours must be selected from other concentrations to satisfy the Biomedical electives. Up to 6 semester credit hours of graduatelevel biomedical engineering courses may be used to satisfy the Biomedical electives, with the approval of the advisor, instructor, Graduate Program Director, and Department Chair. Biomechanics Concentration BME 0 BME 04 BME 20 BME 420 BME 429 BME 470 BME 480 Biomedical Internship Biomedical Research Biomechanics II: Cardiovascular Biomechanics III Topics in Biomechanics Biomedical Thermodynamics Fundamental Computational Bioengineering Biomaterials, Cellular, and Tissue Concentration BME 0 BME 04 BME 40 BME 4 BME 440 BME 442 Biomedical Internship Biomedical Research Biomaterials II Biocompatibility of Materials: Tissue-Biomaterial Interaction Molecular Techniques for Cell-Biomaterials Interactions Tissue /05/6

3 The University of Texas at San Antonio BME 448 BME 449 BME 47 BME 479 Topics in Biomaterials Topics in Tissue Cellular Topics in Cellular Biomedical Imaging and Nanobiotechnology Concentration BME 0 BME 04 BME 50 BME 450 BME 460 BME 46 BME 462 D. Technical Electives Biomedical Internship Biomedical Research Nanomaterials and Nanobiotechnology Biosensors Biophotonics Biomedical Imaging Biomedical Optics A minimum of 9 semester credit hours of Technical Electives must be completed by all students. Depending on interest, students should select appropriate courses in sciences and engineering in order to enhance their basic engineering and scientific training. Examples of Technical Electives are: Courses EE 22 EE 242 EE 5 EGR 20 ME 29 ME 8 Science Courses BIO 44 BIO 2 BIO 9 CHE 260 CHE 262 CHE 64 CHE 40 Electric Circuits and Electronics Network Theory Random Signals and Noise Statics Thermodynamics I Mechanics of Solids Biosciences II Genetics Molecular Biology Organic Chemistry I Organic Chemistry I Laboratory Organic Chemistry II Biochemistry Total Credit Hours 65 B.S. in Biomedical Recommended Four-Year Academic Plan First Year AIS 20 Academic Inquiry and Scholarship (core) 9 Credit Hours BIO 404 Biosciences I (core and major) 4 CHE 0 General Chemistry I MAT 24 Calculus I (core and major) 4 WRC 0 Freshman Composition I (Q) (core) BME 002 Introduction to Biomedical CHE General Chemistry II MAT 224 Calculus II 4 PHY 94 Engineers I (core) 2 PHY 95 Engineers I Laboratory WRC 02 Freshman Composition II (Q) (core) Second Year BME 20 Physiology for Biomedical EGR 20 Statics (Tech Elective) STA 40 Probability and Statistics for the Biosciences MAT 224 Calculus III (Tech Elective) 4 PHY 96 PHY 97 Engineers II Engineers II Laboratory BME 220 Biomechanics I EGR 22 Applied Analysis I BME 00 Biomaterials I BME 4 BME 2 Summer BME 0 Third Year Cellular Biology for Biomedical Biomedical Laboratory I Clinical Internship in Biomedical BME 0 Bioinstrumentation BME Biomedical Laboratory II POL or 2 Texas Politics and Society (core) Technical elective Upper-division BME elective BME 022 Biomedical Technology and Product Development BME 70 Biotransport Phenomena BME 7 Biomedical Laboratory III Upper-division BME elective POL 0 Summer BME 0 Fourth Year Introduction to American Politics (core) Biomedical Internship (BME Elective) BME 490 Senior BME Design I Upper-division BME elective Upper-division BME elective American History core Creative Arts core 4 2

4 Department of Biomedical BME 49 Senior BME Design II American History core Component Area Option core Language, Philosophy and Culture core Social and Behavioral Sciences core Total Credit Hours: 25.0 Biomedical (BME) Courses BME 002. Introduction to Biomedical. (2-0) 2 Credit Prerequisites: A grade of C- or better in BIO 404, CHE 0, and MAT 24, and concurrent enrollment in CHE, MAT 224, PHY 94, and PHY 95. This course is an introduction to the interdisciplinary field of biomedical engineering. Topics covered include core biomedical engineering areas such as Biomechanics, Biomaterials and Bioimaging. Generally offered:. BME 20. Physiology for Biomedical. (-) Credit Prerequisites: Major in Biomedical and a grade of C- or better in BIO 404 and CHE. Fundamental principles of general and organs systems physiology, including composition and concentration of cellular and other body fluids, types of transport (e.g., diffusion, membrane transporters), energy (thermodynamics, metabolism), enzymes, feedback control, and membrane potentials with engineering applications and mathematical modeling. This course includes a hour lecture and a hour recitation. Generally offered:. BME 220. Biomechanics I. (-) Credit Prerequisites: A grade of C- or better in EGR 22 and PHY 96. Introduction to the fundamental engineering mechanics with focus on the human body. This course includes a hour lecture and a hour recitation. Generally offered:. BME 00. Biomaterials I. (-) Credit Prerequisites: A grade of C- or better in BIO 404 and CHE. Introduction to the fundamental science of natural and synthetic biomaterials used for repairing human tissues and organs. Topics include crystal structures, phase diagrams, and properties of materials. This course includes a -hour lecture and a -hour recitation. (Formerly BME 240. Credit cannot be earned for both BME 00 and BME 240). BME 0. Clinical Internship in Biomedical. (0-0) Credit Prerequisites: A grade of C- or better in BME 220, BME 00, and BME 4. This course will introduce students to the clinical environment, interacting with clinicians on current clinical problems and engineering approaches. Generally offered: Summer. BME 022. Biomedical Technology and Product Development. (2-0) 2 Credit Prerequisite: A grade of C- or better in BME 0. This course will introduce students to current biomedical technologies and product development. (Formerly BME 02. Credit cannot be earned for both BME 022 and BME 02.). BME 0. Biomedical Internship. (0-0) Credit Prerequisite: A grade of C- or better in BME 022. Internship with a biomedical industry. May be repeated for credit but no more than semester credit hours will apply to a bachelor s degree. BME 04. Biomedical Research. (0-0) Credit Hour. Prerequisite: Consent of instructor. Advanced laboratory practice and introduction to biomedical engineering research. This course may be counted as one of the courses to satisfy one of the BME tracks. May be repeated for credit but no more than semester credit hours will apply towards a bachelor s degree in Biomedical. BME 042. Biomedical Research. (0-0) 2 Credit Prerequisite: Consent of instructor. Advanced laboratory practice and introduction to biomedical engineering research. This course may be counted as one of the courses to satisfy one of the BME tracks. May be repeated for credit but no more than semester credit hours will apply towards a bachelor s degree in Biomedical. BME 04. Biomedical Research. (0-0) Credit Prerequisite: Consent of instructor. Advanced laboratory practice and introduction to biomedical engineering research. This course may be counted as one of the courses to satisfy one of the BME tracks. May be repeated for credit but no more than semester credit hours will apply towards a bachelor s degree in Biomedical. BME 4. Cellular Biology for Biomedical. (-4) 4 Credit Prerequisites: Major in Biomedical and a grade of C- or better in BME 20 and CHE. Introduction to cell structure and function, energy conversions, protein sorting, signaling, cytoskeleton, cell adhesion, cell cycle, and mammalian genetics. A laboratory component will focus on techniques and procedures commonly used in cell and molecular biology with bioengineering applications. This class includes a -hour lecture and a 4-hour laboratory. (Formerly BME 24. Credit cannot be earned for both BME 4 and BME 24). BME 20. Biomechanics II: Cardiovascular. (-0) Credit Prerequisites: A grade of C- or better in BME 220 and BME 2. Continuation of fundamental biomechanics to include elasticity, viscoelasticity, deformation, stress analysis, blood flow in the systemic and pulmonary circulation, and fluid-structure interaction. Generally offered:. BME 2. Biomedical Laboratory I. (0-4) Credit Hour. Prerequisites: A grade of C- or better in PHY 96 and STA 40. A biomedical engineering lab in biomechanics and biomaterials. This labbased course will emphasize on the synthesis and characterization of mechanical properties as well as physical and chemical properties of biomaterials. (Formerly BME 22. Credit cannot be earned for both BME 2 and BME 22). BME 0. Bioinstrumentation. (-) Credit Prerequisites: A grade of C- or better in BME 220, BME 4, EGR 22, and PHY 96, and concurrent enrollment in BME. Fundamental principles of bioinstrumentation used in clinical and research measurements will be covered. Topics include: principles of transducer operation, amplifiers and signal processing, recording and display. This course includes a hour lecture and a hour recitation. Generally offered:. BME. Biomedical Laboratory II. (0-4) Credit Hour. Prerequisites: A grade of C- or better in BME 4, BME 2, and STA 40, and concurrent enrollment in BME 0. A biomedical engineering lab in bioinstrumentation. This course will involve the design and testing of hardware and software for acquiring and analyzing biological signals. Generally offered:. 4 0/05/6

5 The University of Texas at San Antonio BME 40. Biomaterials II. (-5) Credit Prerequisites: A grade of C- or better in BME 00 and BME 2. This course will emphasize materials used in medical applications, including modifications and characterization techniques. This course includes a hour lecture and a 5 hour laboratory. BME 4. Biocompatibility of Materials: Tissue-Biomaterial Interaction. (-0) Credit Prerequisites: A grade of C- or better in BME 00 and BME 2. This course is an introduction to biocompatibility with special emphasis on the interaction of cells and tissues with biomaterials. Blood composition and blood-material interactions, responses of the inflammatory and immune systems to biomaterials, the process of wound healing, protein structure and interactions with material surfaces, and the mechanisms of cell interactions with extracellular matrix components as well as cell/tissue responses to implant materials are reviewed in detail. Case studies of cardiovascular and orthopaedic implants are discussed to illustrate that selection of biocompatible materials is a key aspect of implant design and a crucial choice for the success of various biomedical applications (e.g., tissue engineering and biotechnology) which require regeneration of tissues. Generally offered:. BME 50. Nanomaterials and Nanobiotechnology. (-0) Credit Prerequisites: A grade of C- or better in BME 00 and BME 2. This course will introduce an overview of nanomaterials and nanotechnology development. Topics may include biocompatible nanomaterials, microfabrication, microfluidics, lab-on-a-chip, and applications in biomedical engineering. (Formerly titled Fundamentals of Nanobiotechnology. ) Generally offered:. BME 70. Biotransport Phenomena. (-) Credit Prerequisites: A grade of C- or better in BME 4, BME 0, EGR 22 and PHY 96, and concurrent enrollment in BME 7. This course introduces the concepts of quantitative modeling of biological systems with respect to mass, momentum and energy transport. We will study the use of conservation laws to model cardiopulmonary, renal, and thermal systems of the human physiology, and also apply these principles to design artificial and extracorporeal devices, drug delivery systems for pharmacokinetic analysis. This course includes a hour lecture and a hour recitation. Generally offered:. BME 7. Biomedical Laboratory III. (0-4) Credit Hour. Prerequisites: A grade of C- or better in BME 4, BME 0, and STA 40, and concurrent enrollment in BME 70. A biomedical engineering lab in biotransport phenomena. Experiments related to mass, momentum, and energy conservation in biological systems such as measurements of apparent viscosity in microcirculation, oxygen diffusivity and thermal conductivity. Generally offered:. BME 420. Biomechanics III. (-0) Credit Prerequisites: A grade of C- or better in BME 20. Topics may include elasticity, viscoelasticity, deformation, stress analysis, strain measurement, and stress and strain in organs. Tissues covered may include heart, blood vessels, cartilage, and bone. BME 42. Tissue Mechanics. (-0) Credit Prerequisite: A grade of C- or better in BME 220. Topics may include biomechanics characterization, modeling, and properties of regenerating tissues ranging from bone, cartilage, tendons, ligaments, skin, adipose tissue, nerves, bladder, eye, and pulmonary and cardiovascular tissues. BME 429. Topics in Biomechanics. (-0) Credit Prerequisites: Senior status with a major in Biomedical and a grade of C- or better in BME 20. Specific topics in biomechanics. May be repeated for credit when topics vary, but not more than 6 semester credit hours will apply to a bachelor s degree. BME 440. Molecular Techniques for Cell-Biomaterials Interactions. (2-4) Credit Prerequisite: A grade of C- or better in BME 00. Advanced molecular techniques for characterizing cell-biomaterials interactions will be taught. Current understanding of topics in cell receptors and signaling mechanisms with application for biomaterial design will be emphasized. Topics will include receptor-ligand communication, methods of identification and quantification, and pathways involved for cell to material stress response. This course includes a 2 hour lecture and a 4 hour laboratory. BME 442. Tissue. (-0) Credit Prerequisite: A grade of C- or better in BME 00. This course is an introduction to the current status of, practice, and advances in tissue engineering, the biomedical engineering discipline that applies science and technology to develop replacements for damaged and/or diseased tissues of the body. The course focuses on fundamental aspects of new tissue formation, specifically, cells, biomaterials, biochemical and biophysical stimuli. Applications in bone, cartilage, skin, and vascular tissues are reviewed in detail. Strategies which are used to address current challenges, pursue emerging opportunities and explore new directions are discussed. BME 448. Topics in Biomaterials. (-0) Credit Prerequisites: Senior status with a major in Biomedical and a grade of C- or better in BME 40. Specific topics in biomaterials. May be repeated for credit when topics vary, but not more than 6 semester credit hours will apply to a bachelor s degree. BME 449. Topics in Tissue. (-0) Credit Prerequisites: Senior status with a major in Biomedical and a grade of C- or better in BME 442. Specific topics in tissue engineering. May be repeated for credit when topics vary, but not more than 6 semester credit hours will apply to a bachelor s degree. BME 450. Biosensors. (-0) Credit Prerequisite: A grade of C- or better in BME 50. Basics to biological detection and in-depth view of device design and performance analyses. Topics may include optical, electrochemical, acoustic, piezoelectric, and nanobiosensors. BME 460. Biophotonics. (-0) Credit Prerequisite: A grade of C- or better in BME 0. This course will introduce the fundamental principles of biophotonics and will focus on their applications to address critical issues in the frontier of biomedical science and technology. Topics may include fundamentals of light interactions with molecules, cells, and tissues, optical imaging, optical biosensing, flow cytometry, photodynamic therapy, laser tweezers and laser surgery, and nanobiotechnology. Generally offered:. BME 46. Biomedical Imaging. (-0) Credit Prerequisites: A grade of C- or better in BME 460. This course will examine, from a systems perspective, the techniques used in a variety of medical imaging modalities, which include x-ray imaging, computed tomography, magnetic resonance imaging, nuclear medicine, ultrasound imaging, and photoacoustic imaging. The fundamental principles and engineering underlying each imaging modality will be discussed and a performance analysis of each system will be examined. 5

6 Department of Biomedical BME 462. Biomedical Optics. (-0) Credit Prerequisite: A grade of C- or better in BME 0. This course will introduce the fundamental principles of modern and classical optics and their applications for biomedical research. State-of-the-art topics on cutting-edge research in the area of optics and lasers in medicine and biology will be covered. BME 470. Biomedical Thermodynamics. (-) Credit Prerequisites: A grade of C- or better in BME 70 and EGR 22. This course is introduces the basics of engineering thermodynamics and applications in biomedical engineering. The course covers first and second laws, properties of pure substances and mixtures, phase rule, phase and chemical equilibria, and an introduction to statistical thermodynamics. This course includes a hour lecture and a hour recitation. BME 47. Cellular. (-0) Credit Prerequisites: A grade of C- or better in BME 70. This course focuses on using engineering skills and principles in the analysis and design of cellular functions. The emphasis will be on protein biochemistry, cell metabolism, signaling and adhesion. BME 479. Topics in Cellular. (-0) Credit Prerequisites: Senior status with a major in Biomedical and a grade of C- or better in BME 47. Specific topics in cellular engineering. May be repeated for credit when topics vary, but not more than 6 semester credit hours will apply to a bachelor s degree. BME 480. Fundamental Computational Bioengineering. (-0) Credit Prerequisites: Major in Biomedical and a grade of C- or better in BME 4 and EGR 22. This course will include fundamental knowledge and skills of mathematical modeling, computer simulation and visualization, with applications in biomedical engineering. BME 490. Senior BME Design I. (-0) Credit Prerequisite: Senior status with a major in Biomedical and a grade of C- or better in BME 022 and STA 40. Development of project proposals and presentation of conceptual designs. Industrial collaboration and/or faculty sponsorship of these projects is encouraged. BME 49. Senior BME Design II. (-0) Credit Prerequisite: Senior status with a major in Biomedical and a grade of C- or better in BME 490. Continuation of the development of an instructor-approved design project, testing of the design project, and presentation of the findings. Industrial cooperation or faculty sponsorship of projects is encouraged. 6 0/05/6

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