Computer assisted decision support in acutely ill patients. Application in glucose management and quantification of myocardial reperfusion

Transcription

1 Computer assisted decision support in acutely ill patients. Application in glucose management and quantification of myocardial reperfusion Vogelzang, Mathijs IMPORTANT NOTE: You are advised to consult the publisher's version (publisher's PDF) if you wish to cite from it. Please check the document version below. Document Version Publisher's PDF, also known as Version of record Publication date: 2008 Link to publication in University of Groningen/UMCG research database Citation for published version (APA): Vogelzang, M. (2008). Computer assisted decision support in acutely ill patients. Application in glucose management and quantification of myocardial reperfusion Mathijs Vogelzang Copyright Other than for strictly personal use, it is not permitted to download or to forward/distribute the text or part of it without the consent of the author(s) and/or copyright holder(s), unless the work is under an open content license (like Creative Commons). Take-down policy If you believe that this document breaches copyright please contact us providing details, and we will remove access to the work immediately and investigate your claim. Downloaded from the University of Groningen/UMCG research database (Pure): For technical reasons the number of authors shown on this cover page is limited to 10 maximum. Download date:

2 Computer assisted decision support in acutely ill patients Application in glucose management and quantification of myocardial reperfusion

3 Financial support by the Netherlands Heart Foundation and the UMCG for the publication of this thesis is gratefully acknowledged. Additional contributions by the following sponsors are gratefully acknowledged: AstraZeneca, B.Braun, Cordis, Interuniversitair Cardiologisch Instituut Nederland, Menarini Farma, Novo Nordisk, Pfizer, Philips, Roche Diagnostics, Sanofi-Aventis, Wyeth Pharmaceuticals Computer assisted decision support in acutely ill patients Mathijs Vogelzang PhD thesis, University of Groningen, the Netherlands ISBN: Cover: screenshots of GRIP and QuBE with fragments of the GRIP source code in the background. Paranimfen: Frank Vogelzang Lieuwe Piers c Mathijs Vogelzang, All rights reserved. No part of this publication may be reproduced, or transmitted in any form or by any means, without permission of the author.

4 RIJKSUNIVERSITEIT GRONINGEN Computer assisted decision support in acutely ill patients Application in glucose management and quantification of myocardial reperfusion Proefschrift ter verkrijging van het doctoraat in de Medische Wetenschappen aan de Rijksuniversiteit Groningen op gezag van de Rector Magnificus, dr. F. Zwarts, in het openbaar te verdedigen op woensdag 21 mei 2008 om uur door Mathijs Vogelzang geboren op 15 augustus 1981 te Groningen

5 Promotor: Copromotor: Prof. Dr. F. Zijlstra Dr. M.W.N. Nijsten Beoordelingscommissie: Prof. Dr. L.P.H.J. Aarts Prof. Dr. W.H. van Gilst Prof. Dr. A.B.J. Groeneveld

6 Contents 1 General introduction and aims of this thesis 7 I Computer assisted analysis of clinical data 2 Hyperglycemic index as a tool to assess glucose control: a retrospective study 15 Crit Care 2004, 8:R122 R127 3 Hyperglycemia has a stronger relation with outcome in trauma patients than in other critically ill patients 29 J Trauma 2006, 60: The impact of a reduced dose of dexamethasone on glucose control after coronary artery bypass surgery. 43 Cardiovasc Diabetol 2007, 6:39 5a Refractory hyperglycemia induced by glucose-insulin-potassium infusion in acute myocardial infarction 53 Neth Heart J 2006, 14: b Glucose metabolism and acute myocardial infarction 59 Eur Heart J 2006, 27: Computer assisted myocardial blush quantification in acute myocardial infarction 65 Submitted

7 Contents II Decision support in critically ill patients 7 Design and implementation of GRIP: a computerized glucose control system at a surgical intensive care unit 79 BMC Med Inform Decis Mak 2005, 5:38 8 Computer-assisted glucose control in critically ill patients 97 Intensive Care Med 2008, accepted 9 Improved potassium control with a nurse-centered computerized protocol: a before and after study. 111 Submitted 10 Summary and future perspective 123 Nederlandse samenvatting 129 Dankwoord 133 Curriculum and list of publications 137 6