Welcome to Biomedicum Open Hearing. Stefan Eriksson, Chair FyFa and Chair Chairman s team

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1 Welcome to Biomedicum Open Hearing Stefan Eriksson, Chair FyFa and Chair Chairman s team

2 Introduction Rationale and organization Ernest Arenas, Chair MBB, Professor of stem cell neurobiology

3 Rationale for Biomedicum Need of expansion in order to meet the growth of the Institutions Renewal of old and outdated laboratories Collect groups thematically, to improve integration and collaboration Improve the usage of expensive equipment and core facilities Need of an animal facility with higher capacity and standards Improve collaboration with NKS and translational research Coordinate and reinforce our efforts in education Improve our administration by adopting standards and best practice Increase visibility at national and international level Attract new recruitments Strengthen Karolinska Institutet and Sweden as an international leading force in health, medical education and science

4 Biomedicum: Project organization Chairman s Team: Marie Arsenian Henriksson MTC Ernest Arenas MBB Stefan Eriksson FyFa Sandra Ceccatelli Neuro Christer Höög CMB Kerstin Lundin PL Responsible for: Organization, Strategic orientation, Research environments, Planning of moving, Communication and more Steering committee: Anders Hamsten Hans-Gustaf Ljunggren Rune Fransson Steering Committee Chair: Anders Hamsten General strategy, decisions Marie Arsenian Henriksson Ernest Arenas Stefan Eriksson Sandra Ceccatelli Christer Höög Facilities/Fastighetsgruppen Responsible for the building according to time and budget. Chairman s team Chair: Stefan Eriksson (Rotating chair) PL: Kerstin Lundin Communication Anna Karin Källén Facilities team PL: Mats Lilja Administration heads team Eva Gipperth Administrative heads team: Marlene Brink-Sinervo/ Marta Pajus MTC Jill Blomstrand MBB Eva Gipperth, Chair, FyFa Åsa Garmager Neuro Riita Ljungström CMB Researchers team Pontus Aspenström Intendents team Åsa Wiktorsson Researchers team: Pontus Aspenström, Chair, MTC Katrin Pütsep MTC Per Uhlén MBB Jonas Fuxe MBB Johanna Lanner FyFa Gunnar Schulte FyFa Ola Hermanson Neuro Christian Broberger Neuro Martin Hällberg CMB Nico Dantuma CMB IT infrastructure Lab interiors Intendents team: Petra Hartley MTC Torbjörn Haglöf MBB Åsa Wiktorsson, Chair, FyFa Boje Persson Neuro Irene Remmel CMB Security Activities coordinated with Animal Facility Verksamhet-KMB Chair: Brun Ulfhake Facilities team PL: Åke Forslund

5 Biomedicum: More than a building! A catalyst for groundbreaking and transformative basic science aiming at improving human health

6 Biomedicum - future importance for Karolinska Institutet A Vice-Chancellor s perspective Anders Hamsten, MD FRCP, Vice-Chancellor

7 Vision Karolinska Institutet significantly contributes to the improvement of human health Strategy 2018 Erik G Svensson

8 Our overarching research goals To achieve scientific breakthroughs that change the view of human health and disease as well as of normal vital processes

9 Current position average citations (Cf) and number of publications (P) Certain data included herein are derived from the Web of Science prepared by THOMSON REUTERS, Inc. (Thomson ), Philadelphiaanities Citation Index Tagged data prepared by the Thomson Scientific Inc (TS), Philadelphia, Pennsylvania, USA: Copyright Thomson Scientific Inc All rights reserved

10 Current position average citations (Cf) and number of publications (P) Certain data included herein are derived from the Web of Science prepared by THOMSON REUTERS, Inc. (Thomson ), Philadelphiaanities Citation Index Tagged data prepared by the Thomson Scientific Inc (TS), Philadelphia, Pennsylvania, USA: Copyright Thomson Scientific Inc All rights reserved

11 Conclusion KI is doing fine as a research institute, but we are far from being in the international lead in terms of how our publications are viewed by the scientific community

12 Strategy 2018 COLLABORATION EMPLOYEES INFRASTRUCTURE FUNDING we want the most qualified for a modernised KI based on joint strategies to finance our investments

13 Opportunities with a large research environment such as Biomedicum Promotes cross-disciplinary research Shared technical infrastructure Efficient use of precious space Possibilities for reinforced administrative support Attractive for recruitments Excellent case for fundraising Enables departmental growth Facilitates establishment of a much-needed large unit for comparative medicine attaining the higher international standards required in the near future

14 Challenges with a large research environment such as Biomedicum Integration Competition for admission to the new environment Allocation of individual groups Perturbations relating to planning, move and re-establishment Costs and distribution of costs Departmental culture clashes

15 Contribution of Biomedicum to Karolinska Institutet s future scientific development Hans-Gustaf Ljunggren, Dean of Research

16 The contribution of Biomedicum to KI s future scientific development

17 The creation of Biomedicum represents a milestone in KI s history 1810 Founded and initially housed in the Royal Bakery at Riddarholmen 1866 Norr Mälarstrand, Kungsholmen 1940 Solna, close to the new Karolinska Hospital 1972 Huddinge Hospital 1982 Novum Research Center, Huddinge 1993 KI93, 150 departments becomes < Aula Medica, Sci Life Lab on the Solna Campus 2018 Biomedicum, new Karolinska University Hospital in Solna, new and renovated research buildings at KI s growing Huddinge Campus

18 The creation of Biomedicum offers enormous opportunities for high quality ground breaking biomedical research

19 The creation of Biomedicum offers enormous opportunities for high quality ground breaking research rationale? Global trend towards larger research infrastructures from an original one house-one subject-one professor -strategy, to fused departments, to large research complexes Allows a mix of a large number of scientists in new creative atmospheres using common facilities and support functions for research Allows more effective use of space

20 The creation of Biomedicum offers enormous opportunities for high quality ground breaking research rationale? Allows strategic locations of individual research groups, clustering around specific subject areas Allows the establishment of larger research infrastructures core facilities Allows more effective, partly centralized, administrative service functions

21 The creation of Biomedicum offers enormous opportunities for high quality ground breaking research rationale? Forms a fantastic platform for recruitment Forms a unique platform for common grant applications Forms a unique platform for fundraising

22 The creation of Biomedicum offers enormous opportunities for high quality ground breaking research rationale? Allows comparisons and co-development with other similar research structures globally

23 The creation of Biomedicum offers enormous opportunities for high quality ground breaking research will it be easy? It will represent a challenge for all involved as it is often when you create history It will involve lots of planning, challenges in moving people, animals, labs, core-facilities etc. It will involve lots of work setting up new functions, new routines, getting established etc.

24 The creation of Biomedicum offers enormous opportunities for high quality ground breaking research will it be easy? But it will be challenging, exciting, opportunities for meeting new people, making new friends and colleagues, and for development For certain, there are many of us at other KI who would have liked to be in your place And, big moves have occurred in the past in the KI history!

25 In parallel with the development of Biomedicum the whole area around the KI Solna Campus will undergo a major transformation in the coming 10 years

26 Our vision of Biomedicum Sandra Ceccatelli, Professor and Chair Dept. of Neuroscience

27 KI s laboratory for the future KI s laboratory for the future OUR VISION OF BIOMEDICUM

28 Biomedicum: KI s laboratory for the future Experimental researchers who today are scattered across the Campus Solna will gather under the same roof with access to ultra-modern laboratories and shared infrastructure.

29 Biomedicum Facts 11 floors 26 lab-quarters ( kvm each) with capacity for 50 persons 1600 persons Skyways to NKS, KM-B and (Wargentin, TBD)

30 FyFa New opportunities and new challenges Neuro MBB MTC CMB

31 Biomedicum Placement in the quarters by research area Space allocation based on vicinity to core facilities, specific infrastructure and collaborators Aula

32 Our goals To provide our scientists with a world-class environment for biomedical research. To promote a new vision on how medical research should be conducted and create the foundation for inter-disciplinary research within the areas of interest of the five departments. To be an innovative platform for recruitment of young and senior elite researchers. To reinforce and improve clinical interactions.

33 Biomedicum - Strategic plan

34 Interactions with external advisors Christian Helin Olli Jänne

35 Visit to the construction site of the Crick Institute in London

36 Visit to the Centre for Veterinary Medicine and Animal Science, Uppsala Participants Jill Blomstrand MBB Riitta Ljungström CMB Åsa Garmager Neuro Pontus Aspenström MTC Boje Persson Neuro Petra Hartley MTC Torbjörn Haglöf MBB Kerstin Lundin UF

37 Biomedicum - Strategic plan

38 FyFa Interdepartmental activities Neuro "Pre-Biomedicum pubs" MBB MTC CMB

39 Biomedicum vision A center for world class science with cutting edge technology aiming at solving fundamental biomedical questions and improving human health A platform that will facilitate interaction, collaborations, and the sharing of experience, ideas and technology across historical borders A rich and dynamic scientific environment with a modern organization and administration

40 Committed researchers and engaged staff are needed to make our vision come true. Welcome on board!

41 Allocation principles Pontus Aspenström, Chair Researchers team

42 How to squeeze 1,600 researchers and staff into one building to stimulate world leading research?

43 Chairman's team Facilities team Researchers team: Pontus Aspenström-MTC (Chair) Katrin Pütsep-MTC Per Uhlén-MBB Jonas Fuxe-MBB Johanna Lanner-FyFa Gunnar Schulte-FyFa Ola Hermanson-Neuro Christian Broberger-Neuro Martin Hällberg-CMB Nico Dantuma-CMB Started August 2011

44 Tools for allocation of space Survey I, spring 2014 Identify number of research groups moving to Biomedicum Identify the size of the research groups Identify the needs of the research groups Identify specific infrastructure Working groups for the design of 4 quarter types Basic quarter and special requirements Quarters with focus on Cell Culture Quarters with focus on BSL2 Quarters with focus on Protein work Lead: Ola Hermansson (Neuro) Sofia Johansson (MTC) Rickard Sandberg (CMB) Dinos Meltis (Neuro) Per Uhlén (MBB) Camilla Svensson (FyFa) Lead: Gunnar Schulte (FyFa) Margareta Wilhelm (MTC) Lena Ström (CMB) Anna Falk (Neuro) Kajsa Wing (MBB) Jorge Ruas (FyFa) Lead: Katrin Pütsep (MTC) Antonio Rothfuchs (MTC) Teresa Frisan (CMB) Håkan Karlsson (Neuro) Jonas Fuxe (MBB) Anna Krook (FyFa) Lead: Martin Hällberg (CMB) Gerald McInerney (MTC) Ana Teixeira (CMB) Björn Högberg (Neuro) Herwig Schüler (MBB) Mattias Carlström (FyFa)

45 Allocation of quarter types, core facilities and common infrastructure A B C D 2D Mercator projection of the building with defined core facilities or structures Imaging FACS BSL3 Proteomics DNA analysis Animal house BioClinicum

46 Biomedicum Floor Meeting rooms A B C D proteomics PCR Imaging ADM Archives storage Histology Lunch room Pre PCR Clean lab Clean lab-lcm EF Freezers storage Meeting rooms EF BSL3 37 o C room Clean lab PCR EF Radioac. lab FACS Deliveries washing Waste handling Chemistry Lunch room PSF Isotope Radioac. lab Imaging EF Lunch room Lecture hall Public show-room Normal Cell (heavy cell culture) BSL2 protein KI Core facilities Biomedicum Common facilities Special Requirements Admin/Support November 21, 2014

47 2015 Detailed design of each quarter This work is done by the Facilities team, Researchers team (reporting to Chairman s team) and architects. In collaboration with Intendents team and Administration heads team.

48 What will happen next? Survey II 2015/2016 Revise number and size of research groups moving to Biomedicum Revise needs of the research groups Allocate space to each research group based on proximity to core facilities, specific infrastructure and proximity to colleagues Workshops 2017 PI and representatives from research groups allocated together in one quarter will meet and decide about sharing of office space, lab space and equipment

49 Closing remarks Marie Arsenian Henriksson, Chair MTC

50 Biomedicum Take Home Messages Our mission is to perform world class science in order to advance knowledge and contribute to improve human health All staff and researchers engaged and committed to our goals, are needed and welcome on board Biomedicum will be a unique new, interactive, multidisciplinary and modern working environment We will improve our critical mass and global visibility We will enhance our capacity to attract funds and recruit top international researchers

51 Laboratory of the Future A catalyst for groundbreaking science aiming at improving human health

52 Thank you for your attention! Time for coffee and mingle: Refreshments will be served outside

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