CO 2. RE Clinical Results. The Results Speak for Themselves

Transcription

1 CO 2 RE Clinical Results The Results Speak for Themselves 1

2 Table of Contents Sections Photo-aged Skin 3-12 Skin irregularities, wrinkles, texture, pigmentation, dyschromia Scars Acne, traumatic, surgical Peri-orbital Treatment Arms, Rhinophyma & Skin Lesions Fractional Laser Resurfacing with CO 2 RE and Sublative Radiofrequency on the Arms: A Case Report 1 By Stacy M. Chimento, M.D., FAAD & Diane Walder, M.D., Private Practice, Bay Harbor Island, Florida, USA Rhinophyma CO 2 RE Laser 2 By Matthew J. Mahlberg, M.D., Lake Loveland Dermatology, Loveland, CO, USA References Ablative Fractional Skin Resurfacing and Facial Scar Reduction with the CO 2 RE Device 3 By David Friedman, M.D., Friedman Skin & Laser Center, Jerusalem, Israel Surgical Scar Reduction with Pulsed Dye Laser and Fractional CO 2 Laser: Combined Vbeam and CO 2 RE Treatment 4 By David Friedman, M.D., Friedman Skin & Laser Center, Jerusalem, Israel CO 2 Laser assisted eyelid surgery and periocular rejuvenation with CO 2 RE laser 5 By Althy Au, M.D., MSc, Aesthetic Plastic Surgery, Cosmetic Surgeon, Hong Kong 2

3 Wrinkles & Texture - Long Term Follow-up 1 Year After 1 Treatment Photos: Craig Mezrow, M.D. Wrinkles & Pigmentation 6 Months After 1 Treatment 1 Month After 2 Treatments Photos: Lenka Kucerova, M.D. Forehead: Mid Mode - Ring 3, 20% Fractional Coverage, 161 mj Nose, Eyelids: Mid Mode - Ring 3, 30% Fractional Coverage, 128 mj Cheeks, Perioral: Fusion Mode - 30% Fractional Coverage, Ring 101 mj, CORE 70 mj 3

4 Wrinkles & Pigmentation 1 Month After Treatment Photos: Lenka Kucerova, M.D. Forehead: Mid Mode - Ring 3, 180 mj Periorbital: Mid Mode - Ring 3, 128 mj Nose: Mid Mode - Ring 3, 30% Fractional Coverage, 143 mj Cheeks: Fusion Mode - 30% Fractional Coverage, Ring mj, CORE 70 mj Perioral: Fusion Mode - 35% Fractional Coverage, Ring mj, CORE 70 mj Wrinkles After Treatment Photos: Dr. Powell Classic Mode - 3 mj, 2 passes 4

5 Pigmentation & Irregular Texture Light Mode (no parameters available) 3 Months After 1 Treatment Photos: Dinesh Maini, M.D. Wrinkles & Irregular Texture 3 Weeks After 1 Treatment Photos: Steven Eubanks, M.D. Cheeks: Mid Mode - 30% Fractional Coverage, Ring size 3, mj 5

6 Wrinkles - Front View 7 days After Treatment Photos: Craig Mezrow, M.D. Fusion Mode - 40% Fractional Coverage, Ring 1, 50mJ, CORE 70mJ Wrinkles - Side View 7 Days After Treatment Photos: Craig Mezrow, M.D. Fusion Mode - 40% Fractional Coverage, Ring 1, 50mJ, CORE 70mJ 6

7 Wrinkles, Pigmentation & Irregular Texture After Treatment Photos: Steven Eubanks, M.D. Fusion Mode % Fractional Coverage, Ring 70mJ, CORE 65 mj Pigmentation & Irregular Texture 4-7 Days After 1 Treatment 4-6 Weeks Follow Up 12 Weeks Follow Up Photos: E. Victor Ross, M.D. Upper Orbital: Light Mode - 50% Fractional Coverage, 45mJ Upper Mouth: Mid Mode - 35% Fractional Coverage, 90mJ Lower Orbital: Mid Mode - 35% Fractional Coverage, 60mJ 7

8 Wrinkles & Pigmentation - Upper Face 4-6 Weeks Follow Up 4-6 Weeks Follow Up Photos: E. Victor Ross, M.D. Lower Cheeks & Forehead: Mid Mode - 30% Fractional Coverage, 75mJ Nose & Upper Cheeks: Mid Mode - 40% Fractional Coverage, 90mJ Peri-Oral: Fusion Mode - 40% Fractional Coverage, 90mJ Wrinkles & Pigmentation - Lower Face 4-6 Weeks Follow Up Photos: E. Victor Ross, M.D. Lower Cheeks & Forehead: Mid Mode - 30% Fractional Coverage, 75mJ Nose & Upper Cheeks: Mid Mode - 40% Fractional Coverage, 90mJ Peri-Oral: Fusion Mode - 40% Fractional Coverage, 90mJ 8

9 Wrinkles & Pigmentation 4-6 Weeks Follow Up 4-6 Weeks Follow Up Photos: E. Victor Ross, M.D. All Face: Light Mode - 50% Fractional Coverage, 60mJ Cheeks: Mid Mode - 40% Fractional Coverage, 90mJ Peri-Orbital & Peri-Oral: Fusion Mode - 40% Fractional Coverage, 90mJ Wrinkles & Pigmentation 4-7 Days After 1 Treatment 4-6 Weeks Follow Up Photos: Jill Waibel, M.D. Lower Cheeks & Forehead: Mid Mode - 30% Fractional Coverage, 75mJ Nose & Upper Cheeks: Mid Mode - 40% Fractional Coverage, 90mJ Peri-Oral: Fusion Mode - 40% Fractional Coverage, 90mJ 9

10 Wrinkles Fusion Mode: Lower 2/3 of face Deep Mode: 5% Fractional Coverage, 70 mj Mid Mode: Periorbital and forehead 129 mj After 1 Treatment Photos: Amy Forman Taub, M.D. Pigmentation & Texture 5 Days After Treatment Photos: Susan Tanne, M.D. Mid Mode: Ring 3, 30% Fractional Coverage, 111mJ 10

11 Photo-damaged Skin After 1 Treatment Photos: Amy Forman Taub, M.D. Perioral: 2 Passes of Deep Mode 5% (70 mj) followed by 1 pass of Fusion Mode at 40% (Deep Mode 70 mj and Mid Mode 129 mj). Periorbital: 1 Pass of Deep Mode 5% (70 mj) followed by 1 pass of Mid Mode 40% Ring Size 3, 259 mj. Forehead: glabellar area and strip along brows: 1 pass of Deep Mode at 5% at 70 mj followed by 1 pass of Mid Mode 40% Ring Size 3 and 259J; the rest of forehead Mid Mode only - same parameters. Cheeks: Fusion Mode at 40% Deep Mode 70 mj and Mid Mode 129 mj. At jawline same paramaters except at 30%. Wrinkles & Pigmentation 7 Days After Treatment Photos: Susan Tanne, M.D. Cheeks: Mid Mode - Ring 3, 30% Fractional Coverage, 128mJ 11

12 Pigmentation & Irregular Texture (Parameters not available) 3 Months After 1 Treatment Photos: Dinesh Maini, M.D. Wrinkles Deep Mode: 1 st treatment - 5% Fractional Coverage, 60mJ 2 nd treatment - 5% Fractional Coverage, 70mJ After 2 Treatments, at Intervals of 2 Months Photos: Davide Brunelli, M.D. 12

13 Traumatic Scar 3 After 2 Treatments Photos: David Friedman, M.D. Skin Type IV Deep Mode - 5% Fractional Coverage, 70mJ, single pass (1st treatment). Fusion Mode - 40% Fractional Coverage, Deep: 70mJ, Mid: 257mJ single pass (1st treatment). Light Mode - 40% Fractional Coverage, 25mJ, single pass (2nd treatment). Traumatic Scar 3 After 2 Treatments Photos: David Friedman, M.D. Skin Type IV Deep Mode - 5% Fractional Coverage, 70mJ, single pass (1st treatment). Deep Mode - 5% Fractional Coverage, 70mJ, double pass (2nd treatment). 13

14 Acne Scars After 2 Treatments Photos: Nariaki Miyata, M.D. Dimple Area: Fusion Mode - 25% Fractional Coverage, Ring 60mJ, CORE 60mJ Whole Area: Deep Mode - 5% Fractional Coverage, 50mJ Acne Scars (Parameters not available) After 1 Treatment Photos: Alain Braun, M.D. 14

15 Scar After 3 Treatments Photos: Alain Braun, M.D. (Parameters not available) Acne Scars After 3 Treatments Photos: Davide Brunelli, M.D. Deep Mode: from 40 to 70 mj 15

16 Acne Scars After 3 Treatments Photos: Davide Brunelli, M.D. Deep Mode: from 40 to 70 mj Acne Scars Deep Mode: from 40 to 70 mj After 3 Treatments Photos: Davide Brunelli, M.D. 16

17 Herpes Scars After 4 Treatments, at Intervals of 2 Months Photos: Davide Brunelli, M.D. Deep Mode: 1 st treatment - 5% Fractional Coverage, 50mJ 2 nd treatment - 5% Fractional Coverage, 60mJ 3 rd treatment - 5% Fractional Coverage, 70mJ 4 th treatment - 5% Fractional Coverage, 70mJ Combination Therapy - Surgical Scar 4 Tx 1 Tx 2 Tx 3 1 Month After Tx 3 3 Months After Tx 3 Photos: Joel L. Cohen, M.D. 57 year old male with Skin Type II Vbeam (PDL) - spot size 10mm, fluence 7.5J/cm 2, pulse duration milliseconds (1st treatment) CO 2 RE Fusion Mode - 25% Fractional Coverage, spot size 8.4x8.4mm (1st treatment) CO 2 RE Fusion Mode - 30% Fractional Coverage, spot size 7.8x7.8mm (2nd and 3rd treatments) 17

18 Periocular Rejuvenation 5 Day 2 Day 3 Photos: Althy Au, M.D. Deep Mode - 5% Fractional Coverage, mj is used for cases requiring eyelid skin tightening Periocular Rejuvenation 5 After Treatment Photos: Althy Au, M.D. Deep Mode - 5% Fractional Coverage, mj is used for cases requiring eyelid skin tightening Periocular Rejuvenation 5 After Treatment Photos: Althy Au, M.D. Deep Mode - 5% Fractional Coverage, mj is used for cases requiring eyelid skin tightening 18

19 Surgical Mode - Removal of Fat Pads 5 After 1 Week After 3 Weeks After 4 Weeks Photos: Althy Au, M.D. Surgical Mode W, 2 mm spot size in focused and defocused settings, which provides a bloodless incision of soft tissue to achieve conjunctival incision and fat pad excision. Peri-orbital 3 Months After 1 Treatment Photos: Steven Eubanks, M.D. Peri-orbital Mid Mode - 40% Fractional Coverage, Ring size 1, mj 19

20 Fine Vaporisation of Periorbital Benign Skin Lesions Classic Mode: 2 mm, 3 mj After Treatment Photos: Davide Brunelli, M.D. Fine Vaporisation of Periorbital Benign Skin Lesions Classic Mode: 2 mm, 3 mj After Treatment Photos: Davide Brunelli, M.D. Fine Vaporisation of Periorbital Benign Skin Lesions After Treatment Photos: Davide Brunelli, M.D. Classic Mode: 2 mm, 3 mj 20

21 Skin Rejuvenation - Arms After Treatment Photos: Diane Walder, M.D. Light Mode - 30% Ring 1, 30 mj Light Mode - 50% Ring 1, 30 mj Skin Rejuvenation - Arms Light Mode - 30% Ring size: 1 Ring: 25.5 mj Pattern size: 8.0x9.1 D: 9.0mm Shape: Hex After 1 Treatment Photos: Jill Waibel, M.D. 21

22 0 hr and 24 hrs After Classic Mode This photograph shows char formation and ablative depth under different energy setting, also comparing healing process immediately after and one day after. Depth of ablation is very important for dermatologists. According to Dr. Yoshiie, the optimal energy necessary to reach to the basal layer while minimizing inflammation would be 3mJ. 10mJ 9mJ 7mJ 5mJ 3mJ 10mJ 9mJ 7mJ 5mJ 3mJ 0 hr 24 hr 24

23 Classic Mode: Upper eyelid 1.5mm 3mJ 0 Hr 24 Hr This histology photograph shows precise ablation and minimum inflammatory reaction 1 day after using 3mJ Classic Mode: Upper eyelid 1.5mm 5mJ 0 Hr 24 Hr This histology photograph shows precise ablation and minimum inflammatory reaction 1 day after using 5mJ 25

24 Classic Mode: Upper eyelid 1.5mm 7mJ 0 Hr 24 Hr Classic Mode: Upper eyelid 1.5mm 9mJ 0 Hr 24 Hr 26

25 The CO ² RE Advantage CO 2 RE is the versatile fractional CO 2 system that enables you to precisely target and effectively treat the skin s surface, middle and deep dermal levels, plus perform traditional CO 2 resurfacing and laser excision of lesions. Grow your practice with this lighter, faster, and more versatile solution for skin resurfacing, wrinkle and scar reduction, traditional ablation and minor dermal excisions. CO 2 RE gives you the ability to treat both superficial and deep skin layers simultaneously with precision-control over the intensity, pattern and depth of ablation. Modes CO 2 RE Light CO 2 RE Mid CO 2 RE Deep CO 2 RE Fusion Description Provides superficial fractional treatments in the epidermis increasing epidermal cell proliferation. Penetrates more deeply for a stronger fractional ablative effect, producing additional coagulated tissue below the dermalepidermal junction. Penetrates through to the dermis for the deepest fractional ablative effect, surrounded with significant coagulated tissue deeper into the dermis. Unique scan pattern combines treatment depths and intensity of thermal injuries to optimize treatment in the epidermis and dermis simultaneously. Pattern Traditional CO 2 Resurfacing Mode Shapes Circle Rectangle Square Dermal Excision Mode Shapes Circle Segment Freehand Reusable Handpiece Surgical Handpiece We ve been very happy with the results that we ve seen using CO2RE. It has a lot of versatility and we find it works well for both fractionated ablative resurfacing as well as traditional ablative resurfacing. Brian Zelickson, MD, Dermatologist, USA 27

26 CO 2 RE System Specifications Laser Type CO 2 Wavelength Laser Emission Mode Output Power Laser Beam Energy Pulse Repetition Rate Pulse Duration Maximum Scan Area Aiming Laser Articulated Arm Lens Assemblies Handpiece User Interface 10,600 nm Pulsed, CW 60 Watts (maximum peak) Up to 80 mj Up to 16.7 khz Up to 1100 µsec 10 mm diameter 5 mw, 650 nm (red) diode laser Lightweight, aluminum fiber, -7joint, pneumatically balanced Treatment radius at full arm extension: 85 cm (33.5") Horizontal rotation: µm spot size 120 µm spot size (optional) Multi-use or surgical hand piece 10.4" high-resolution color LCD Touch-screen technology Science. Results. Trust. Syneron and Candela are the global leaders in the aesthetic medical device marketplace. We are one company with two distinctive brands. We combine a level of innovation, expertise and customer understanding superior to that of any company in our industry. Financial stability, through our aligned resources, allows our new company to offer customers the broadest available product portfolio, the best global service organization and an expansive worldwide distribution network. Together, we are more market responsive than ever before. We know how to quickly innovate safe and effective products to meet a variety of needs and price points. We are even stronger at anticipating future market trends to help support our customers and their patients. With new breakthrough technologies currently in the pipeline, we are ideally positioned to maintain our global leadership and continue to help you grow your practice. Syneron and Candela have offices and distributors around the world All rights reserved. Syneron, the Syneron logo and CO2RE are trademarks of Syneron Medical, Ltd. and may be registered in certain jurisdictions. Candela is a registered trademark of Candela Corporation. PB88631EN