Performance. All You Need. All In One.

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1 Performance. All You Need. All In One. Skin & Hair Treatments

2 Performance. All You Need. All In One. In the world of multi-application platforms, performance is everything. From treatment time to clinical outcome and patient satisfaction, performance is the measure of success. It s also the distinct difference of M22. M22 is the gold standard platform for the treatment of skin conditions and hair removal. Used by physicians around the world, M22 is the multi-application platform that enables you to treat more types of patients and conditions with better outcomes. Lumenis proudly adds the new ResurFX TM module for non-ablative fractional skin resurfacing to the M22 system. So now, in one device, practitioners have the ideal platform - the world s best IPL module combined with the only CoolScan TM enabled fractional non-ablative module with no disposables, the ResurFX. Performance. Innovative Rely on Lumenis, the most trusted and innovative name in aesthetic devices Modular Invest in smart, robust technology - 3 modules for superior clinical results Versatile Treat more than 40 indications Validated Clinically validated in over 80 peer reviewed papers Experienced Easy-to-use with Lumenis presets for each treatment M22 grows with your practice expands to your treatment needs and adapts to future applications as they emerge.

3 M22 - Three Gold Standard Technologies In One Platform IPL with Optimal Pulse Technology (OPT TM ) provides 24 indications for use ResurFX with CoolScan TM Technology provides 9 indications for use Nd:YAG with Multiple Sequential Pulsing Technology provides 10 indications for use Clinical Indications Indications IPL ResurFX Nd: YAG Hair Removal Permanent Hair Reduction Rosacea Superficial Telangiectasias Deep Telangiectasias Truncal Telangiectasias Vascular Lesions Hemangiomas Port Wine Stains Venous Malformations Angiomas Spider angiomas Leg Veins Reticular Veins up to 4.0 mm Solar Lentigines Indications IPL ResurFX Nd: YAG Ephelides (freckles) Epidermal Pigmented Lesions Dermal Pigmented Lesions Hyperpigmentation Dyschromia Poikiloderma of Civatte Scars Acne Scar Surgical Scars Melasma Striae Skin Resurfacing Periorbital Wrinkles Superficial Wrinkles Warts 20 Years of Leadership in Multi-Application Platforms and IPL Technology Lumenis Invented, Advanced and Perfected IPL 1993 IPL Invented by Lumenis Intense Pulsed Light, Lumenis proprietary, versatile technology was invented. Over 10,000 IPL Platforms sold since EpiLight Dedicated single application IPL systems 2013 ResurFX 1998 VascuLight M22 Non-ablative fractional 1565nm laser module 1st Multi-application, multi-technology platform, with IPL and Nd:YAG technologies 2010 M22 4th generation multi-application, 2000 Quantum multi-technology platform with IPL + Nd:YAG + future technologies 2nd generation IPL multiapplication and upgradable platform 2003 Lumenis One 3rd generation multi-application, multitechnology platform, with IPL, Nd:YAG and LightSheer technologies. IPL with OPT invented

4 Universal IPL One Applicator for All IPL Applications M22 s Universal IPL module enables you to treat a myriad of conditions with a single, versatile handpiece. The Universal IPL handpiece is designed with 6 ExpertFilters tailored to the condition being treated and computer-enabled filter recognition for enhanced safety and ease-of use. With the Universal IPL handpiece, change ExpertFilters in seconds instead of attaching a whole new handpiece. The Universal IPL handpiece saves not only treatment time and storage space, but is also extremely cost efficient because there is no need to purchase multiple IPL handpieces. 6 ExpertFilters For Easy-to-Customize Treatments 515 nm 560 nm 590 nm 615 nm 640 nm 695 nm SapphireCool TM Light Guides Two Sizes for Large and Small Areas Large spot size Small spot size Maximize patient comfort via efficient continuous contact cooling Quickly switch light guides to treat larger or smaller areas The large spot size increases treatment speed by up to 3.5 times. Treat a face in 15 minutes, remove hair on legs in 25 minutes. 8 mm x 15 mm M22 is Lumenis latest advancement in IPL technology, offering efficacy that is second to none, improved patient comfort, speed, versatility and the reliability for which Lumenis is known. This translates into increased patient satisfaction and increased profitability. 15 mm x 35 mm Mitchel P. Goldman, M.D., Founder and Medical Director of Goldman, Butterwick, Keel Cosmetic Laser Dermatology and Volunteer Clinical Professor of Dermatology/Medicine at UC San Diego, USA.

5 IPL with Optimal Pulse Technology The optimal way to broaden a patient base, comfortably Only M22 IPL with Optimal Pulse Technology can deliver both low and high fluences over the entire range of both short and long pulses to safely and effectively treat the broadest range of patients. IPL with OPT Out-Performs Other IPL Systems OPT gives M22 the ability to control IPL pulse shape. While traditional pulsed light systems have a peak of energy at the beginning of the pulse, followed by a decline, Lumenis M22 can equalize the distribution of energy over the entire pulse or over sequential pulses. This delivers the appropriate energy in the safest manner, with high efficiency and reproducible results. In clinical trials conducted on Lumenis IPL 4 th generation devices, it was found that lower fluences (J/cm 2 ) were able to attain the same level of efficacy as older technology systems. Lower effective fluences means a gentler, more comfortable, patient-friendly procedure. Fluence 35 0 Fluence Pulse Duration (ms) Pulse Duration (ms) M22 IPL with OPT M22 IPL with OPT High-powered IPL without OPT High-powered IPL without OPT Limited capabilities of lower-powered systems Limited capabilities of lower-powered systems The OPT advantages: High peak power, shorter pulses optimal for IPL skin treatments using photorejuvenaetaion and the treatment OPT of benign advantages: pigmented lesions. The High peak power, shorter pulses optimal for IPL skin Homogeneous power over long pulse durations safe treatments using photorejuvenaetaion and the treatment of benign pigmented lesions. for hair removal on darker skin types. Homogeneous treatment of power benign over pigmented long pulse durations lesions. safe for hair removal on darker skin types. The OPT advantages: High peak power, shorter pulses optimal for IPL skin treatments using photorejuvenation and the Homogeneous power over long pulse durations safe for hair removal on darker skin types. M22 delivers the largest range of possible combinations of pulse durations and fluences. Clinical Results IPL treatment of rosacea Courtesy of Mariela Nazar, M.D. After 4 Treatments IPL skin treatments using photorejuvenation. Courtesy of Girish Munavalli, M.D. After 1 Treatment

6 The Only Nd:YAG with Multiple Sequential Pulsing Technology The Nd:YAG module of M22 supplements the capabilities of the IPL module and offers treatments for telangiectasias, hemangiomas, various other vascular lesions, leg veins and the non-ablative treatment of facial wrinkles. The two SapphireCool light guides increase patient comfort by providing continuous contact cooling and are easily changed to treat larger or smaller areas, to ensure precise treatment. Computer enabled light guide recognition provides the added margin of the safety you want. Only M22 Has Multiple Sequential Pulsing Multiple-Sequential Pulsing, on both the IPL and the Nd:YAG modules, protects the epidermis, allowing the safe use of higher fluences. It may also improve the efficacy in the clearance of vascular lesions*. Pulse1 Off Pulse1 Off Pulse1 How it works: Light energy is delivered during the pulses, and the tissue cools during the delays. More energy is safely delivered to the target. Injury threshold What it does: Temperature Multiple-Sequential Pulsing allows for cooling between pulses to safely remove hair on all skin types including darker skin and reduces the chance of skin damage in vascular lesion treatments. 2mm X 4mm light guide Epidermis Lesion 6mm light guide Clinical Results Port wine stain. Combination of IPL and Nd:YAG treatment. Courtesy of Matteo Tretti Clementoni, M.D. After 5 treatments Vascular lesions. Courtesy of Mitchel P. Goldman, M.D. Immediately After Treatment *Pavan K.Nootheti, MD; Kimberly A. Pettit, MD; Gail Yosowitz, BS; Mitchel P. Goldman, MD. Clinical Improvement of Photodamaged Skin After a Single Intense Pulsed Light Treatment. The American Journal of Cosmetic Surgery Vol. 24, No. 1, 2007.

7 ResurFX for True Fractional Non-Ablative Skin Resurfacing The ResurFX module of M22 is the only true fractional non-ablative technology one pass is all it takes. Unlike other fractional technologies, ResurFX needs only one pass to be effective, saving you time and protecting the patient s skin. ResurFX uses a 1565 nm fiber laser and a very advanced scanner, which enables you to choose from more than 600 combinations of shape, size and density for optimal treatment results. ResurFX - Invest in the Affordable and Comfortable Wrinkle Treatment Technology Modular technology Cost effective upgrade for M22, no need to invest in a separate system. No consumables. ResurFX handpiece Ergonomic handpiece with good treatment site visibility and an aiming beam for placement precision. Efficacious & fast The best non-ablative fractional treatment for wrinkles in a single pass, unlike other fractional technologies. Up to 20% coverage in ONE pass. Extremely versatile Perform 9 in-demand treatments including: acne scars, surgical scars, dyschromia, melasma, skin resurfacing, striae and periorbital wrinkles. Customize treatments with 6 shapes, 10 densities, various sizes (5-18 mm). Predictable & reproducible results The outstanding scanning capabilities of the CoolScan scanner ensure that the energy delivery of the micro-beams is precise, homogenous and uniform. Easy-to-use Intuitive user interface and user presets make it easy to master ResurFX. Energy 70 mj / microbeam ResurFX with CoolScan* for Optimal Treatment The ResurFX module has a state-of-the-art CoolScan scanner for non-sequential scanning which places each fractional spot in a controlled manner to protect the tissue from heat accumulation and overheating. This ability is unique to the ResurFX 1565nm module. The ResurFX handpiece is equipped with continuous contact cooling, to increase patient comfort during treatment and protects the epidermis. HEXAGON DONUT CIRCLE SQUARE RECTANGLE LINE 5 mm 8 mm 10 mm 12 mm 15 mm 18 mm 50 spots/cm spots/cm spots/cm spots/cm spots/cm spots/cm 2 Over 600 treatment parameters - shapes, sizes and densities - to provide the best, customized treatment. 1 month after 3 rd treatment Striae treatment with ResurFX. Courtesy of Mitchel P. Goldman, M.D. * Patent pending. The ResurFX module of M22 is available in the U.S. pending U.S. Food and Drug Administration (FDA) clearance.

8 LB Lumenis - A Trusted Path to Superior Outcomes A Lumenis trusted is path a global to innovator superior of outcomes. aesthetic medical devices which reflect the real-world Lumenis need of is physicians. a global innovator We of provide aesthetic forward-thinking, technologies which differentiated reflect the real-world platform needs systems of physicians. We supported provide forward-thinking, by superior service differentiated programs. platform Selecting systems supported one of our by superior product service is, in programs. fact, Selecting choosing one a of trusted our products path to is, superior in fact, choosing and consistent a trusted path results. to superior and consistent results. s Specifications M22 System Size IPL Module 44 cm x 50.5 cm x 47 cm; in x in x 18.5 in Weight Applications IPL Skin Treatments, Vascular Lesions, Pigmented Lesions, Permanent 40 kg or 88 lbs Hair Reduction Electrical Spectrum Requirement Universal nm power supply Universal ExpertFilters IPL 515, 560, 590, 615, 640, 695 nm Energy Density (Fluence) Applications J/cm IPL Skin 2 Treatments; Vascular Lesions; Pigmented Lesions; Permanent Hair Reduction Pulse Duration 4-20 ms Spectrum nm Pulse Delay ms M22 with ExpertFilters Pulse Characteristic Multiple 515, Sequential 560, 590, Pulsing 615, 640, 695 nm optional cart Energy Repetition Density Rate (Fluence) Up to Hz J/cm 2 Pulse Spot Duration Size 35 mm 4-20 x 15 mm; ms 15 mm x 8 mm Cooling Continuous contact cooling Pulse Delay ms AMERICAS Nd:YAG Module San Jose, CA Pulse Characteristic Leg Veins, Multiple-Sequential Deeper Vascular Pulsing Lesions, Non-Ablative Treatment of Facial Tel Applications Repetition Rate Wrinkles Up to 1 Hz Wavelength 1064 nm Fax Spot Sizes Energy Density (Fluence) 15 mm x 35 mm, 8 mm x 15 mm J/cm 2 Cooling Pulse Duration Multi-Spot Pulse Delay Nd:YAG 2-20 mscontinuous contact cooling ms EUROPE / MIDDLE EAST / AFRICA Pulse Characteristic Multiple Sequential Pulsing Dreieich-Dreieichenhain Applications Leg Veins; Deeper Vascular Lesions; Non-Ablative Treatment of Facial Wrinkles Germany Repetition Rate Up to 1 Hz Spectrum 1064 nm Tel Spot Size 6 mm, 2 mm x 4 mm Fax Energy Cooling Density (Fluence) Continuous contact J/cm 2 cooling Rome, Italy Pulse Tel ResurFX Duration Module 2-20 ms Fax Pulse Acne Scars, Dyschromia, Melasma, Periorbital Wrinkles, Skin Applications Delay ms Resurfacing, Striae, Surgical Scars London, UK Pulse Tel Wavelength Characteristic 1565 nmmultiple-sequential Pulsing Fax Repetition Pulse Energy Rate Up mj to per 1 Hz micro-beam Spot Pulse Sizes Characteristic Pattern Shapes Cooling CoolScan 2 mm Scanner x 4 mm, 6 mm Line, square, rectangle, circle, donut, hexagon Continuous contact cooling ASIA / PACIFIC Beijing, China Repetition Rate From 0.5 to 2 Hz Tel Spot Size 18 mm Gurgaon, India Tel AMERICAS Cooling EUROPE / MIDDLE EAST Continuous / AFRICA contact cooling ASIA / PACIFIC JAPAN Ensure Compliance with Government Hong Kong Beam density Up to 500 microbeams/cm 2 Santa Clara, CA Dreieich-Dreieichenhain, Beijing, China Safety and Performance Tokyo Standards Tel Tel System Specifications Germany Tel LUMENIS Tel ( ) Fax Dimensions (without Tel ResurFX) x x 47 cm (17 x 20 x 18.5 inches) Outside USA, visit Fax Gurgaon, India Fax Fax click Service & Support Dimensions (with ResurFX) 44 x 50.5 x 61.5 cm (17 Tel X X inches) Rome, Italy JAPAN Weight (without ResurFX) Tel kg. / 88 lbs. Hong Kong Tokyo Weight (with ResurFX) Fax Tel Ensure Compliance with Government kg. / 121 lbs. Tel Fax Safety and Performance Standards Fax Umbilical Cable Length London, UK 170 cm / 67 inches LUMENIS ( ) Tel Electrical requirements Outside USA, visit Fax VAC ±10%, 12A/8A, 50/60 Hz, click single Service phase, & Support dedicated line. LASER CLASS 4/IV CO 2: 10.6 m, 60W Max, CW Max Pulse Width: 550 s Max Pulse Energy: 30mJ LASER CLASS 3R/IIIa Diode Laser: 635nm, 5mW Max, CW VISIBLE AND INVISIBLE LASER RADIATION AVOID EYE OR SKIN EXPOSURE TO DIRECT OR SCATTERED RADIATION CLASS 4 LASER PRODUCT per EN /2001 CLASS IV LASER PRODUCT per 21 CFR & except for deviations pursuant to Notice 50, Dated June 24, Ensure Compliance with Government Safety and Performance Standards LUMENIS ( ) Outside USA, visit click Service & Support LASER CLASS 4/IV 1565nm, 15W Max, CW Max Pulse Width: 10 ms Max Pulse Energy: 70 mj LASER CLASS: 3R/IIIa Diode Laser: 650nm, 5mW Max, CW VISIBLE AND INVISIBLE LASER RADIATION AVOID EYE OR SKIN EXPOSURE TO DIRECT OR SCATTERED RADIATION CLASS 4 LASER PRODUCT per EN /2007 CLASS IV LASER PRODUCT per 21 CFR 1040 LB Group of Companies. All rights reserved. Lumenis, its logo, M22, IPL, OPT, Multi-Spot, ChillTip are trademarks or registered trademarks of the Lumenis s. Specifications are subject 2013 to change All Rights without Reserved. notice. The This Lumenis device is Group in compliance of Companies. with the PB DE European medical Rev. A. device directive Lumenis, its logo, M22, IPL, OPT, Multiple-Sequential Pulsing, ExpertFilters, SapphireCool PB Rev. C lightguides, CoolScan, ResurFX are trademarks or registered trademarks of the Lumenis Group of Companies. Specifications are subject to change without notice.

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