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1 SHR Pain Free Hair Free Brochure Treatment Laser Hair Removal AFT Hair Removal

2 SHR by Alma Lasers Pain Free Hair Free Alma Laser s SHR technology is the world s most popular and widely used method of laser hair removal. Pain free SHR is the only clinically proven method of laser and AFT hair removal that causes virtually no pain. SHR works by gradually heating the dermis to a temperature that effectively damages the hair follicle and prevents re-growth, while not injuring surrounding tissue. SHR combines high average power, low fluence, and a high repetition rate; gradually increasing the temperature of the hair follicle by stacking the laser pulses. All hair and skin types SHR gradually heats the skin until the required cumulative energy is delivered to the hair root. By not exposing the hair root to a single high energy pulse, SHR doesn t cause trauma to skin with high melanin count, making it the safest laser hair removal option for dark skinned individuals. Furthermore, SHR treatment can be performed any time during the year, as sun exposure is less traumatic to the skin following SHR treatment. All you need is SHR The sweeping In-Motion technique of moving the hand piece repeatedly over the treatment area virtually eliminates pain, and removes the need for gels or anesthetics. Patients show up for a quick treatment, and are back out the door within a few minutes. 2-3

3 Diode 810 SHR Pro Technology Traditional method The pain associated with laser hair removal is dependant on the amount of energy that is being applied to the skin with each laser/light pulse. Because the areas containing chromophores (root and bulb) are destroyed at 50 C - 60 C, the way that the energy is delivered to reach this temperature will dictate the level of discomfort. Traditional bulk heating methods effectively raise the root, bulb and surrounding area to the therapeutic temperature, but cause intense pain due to the high energy delivered in a single pulse. Pulsed stacking SHR technology employs low fluence, high average power, with super fast pulses. SHR does not solely target melanin as the principle chromophore. Instead, SHR focuses on progressively raising the temperature of the sub-dermal layer of the skin in a step-wise fashion. SHR raises and maintains the temperature to 45 C - 50 C, trapping the heat for prolonged time and thereby deactivating the surrounding biological markers (e.g., stem cells and enzymes) for permanent hair reduction. Modules SHR can be performed with a 810-nm diode laser technology, the gold standard in laser hair removal. The laser has a powerful diode treatment head that delivers up to 120 J/cm 2 deep into the dermis with high average power and a rapid 10 pulse-per-second repetition rate. In addition, SHR can be performed with AFT, Alma Lasers advanced IPL technology found on the Harmony XL and Harmony LITE platforms. Dermis ~45 C Epidermis ~25 C with cooling Hair Follicle ~50 C during SHR procedure 4-5

4 Patient Safety & Treatment Efficacy SHR technology is the safest method of laser hair removal, as well as the most effective. Grid method During SHR treatment, energy is applied over a large grid, not just the region of the hair follicle. The grid method of treatment ensures that all hair follicles absorb the energy, dramatically improving treatment results, while significantly reducing treatment time. Patient safety SHR has been proven in multiple clinical studies as the safest method of laser hair removal for all skin and hair types; as the melanin in dark skin types is exponentially more sensitive to the heat in laser treatment. Hair follicles are damaged not by a single high energy pulse, but by repetitive application of low fluence pulses - removing the sensation of pain. Furthermore, the individual pulses do not cause any burning to the skin, as it is the multiple pulses that raise the temperature of the dermis to the level needed to prevent hair growth. SHR technology further ensures that the temperature of the dermis rises above 42 C (for effective hair removal) but not above 50 C, which could cause pain, burns, and permanent skin discoloration. Skin cooling Cooling for SHR comes from the Sapphire tip on the handpiece.the sapphire tip increases patient comfort, virtually eliminating the need for cold gels or analgesics. 6-7

5 SHReconomics Laser hair removal is among the leading non-invasive aesthetic treatments performed today. With over 12 million laser hair removal treatments performed in 2011 alone, and a growth rate of 18%, hair removal is a fantastic way to inject profit into your practice. While there are many laser treatments available, only SHR can maximize your return on investment while minimizing the risk of patient injury. Pain Free - SHR is the only laser treatment for hair removal that doesn t cause pain. All Hair Types - Powerful diode treatment head with up to 120 J/cm 2 allows treatment of nearly any type of hair. No other laser can compare. Gradual skin heating Grid method of treatment Reliable results - Consistency in every treatment with effective permanent reduction in hair with no side effects. All Skin Types - The unique pulsing (10-1,350 ms) of the SHR modules provides a safe and effective way for treating patients with any skin type, including tanned and dark skin. All Times of the Year - SHR can be used anytime during the year as it does not heat up the melanin in the same way as other lasers. No Burns - With SHR short pulse duration, the skin is not heated to the point of burning, eliminating the risk of patient injury and potential lawsuits. Brand recognition - SHR is the only laser hair removal treatment with brand recognition among patients. Proven efficacy - SHR is the only pain free laser hair removal technology with proven clinical studies. Coagulative necrosis and shrinkage of the central components of the hair follicle Histologies courtesy of Dr. Tania Meneghel, São Paulo, Brazil Epithelial thinning and dilation Eliminate consumables - SHR requires no office consumables, anesthesia or numbing gels, maximizing your investment. 8-9

6 Systems Alma Lasers provides multiple options for laser hair removal with SHR technology. Soprano Soprano is the world s best-selling laser system for hair removal. Soprano is used in nearly every country in over 3,000 clinics. Soprano hair removal technologies and modules include; SHR pain-free hair removal with pulsed-stacking; LHR - regular laser pulse hair removal; and NIR - skin tightening using near-infrared light. Harmony Harmony is a laser and light platform for the aesthetic treatment of over 65 FDA-cleared indications. Harmony is designed as a modular platform, providing multiple laser technologies and wavelengths via a wide array of modules and tips. With the advent of Harmony, physicians can now perform the widest range of applications ever available on a single system. Harmony s technologies have been carefully selected and refined to not only provide excellent safety and efficacy, but to ensure the highest levels of predictability, reliability and reproducible results. Harmony s SHR modules works on an AFT protocol, as opposed to the Soprano s 810 diode laser. Harmony LITE Harmony LITE is a new platform for aesthetic treatments, featuring Alma Lasers proprietary Advanced Florescence Technology. AFT is an advanced type of IPL which utilizes the photons from all wavelengths, including the wavelengths that are filtered out of the spectrum. The increased energy leads to enhanced clinical results, less pain and downtime, while extending the lifetime of the handpiece. The modular design of the Harmony LITE delivers multiple cosmetic solutions, including the SHR and Dye-PL handpieces. With Harmony LITE, you can purchase only the IPL handpieces Soprano XLi Harmony XL Harmony LITE you require today and add new technologies as your practice grows

7 Clinical Results Clinical Studies SHR technology has been the subject of numerous white papers, peer reviewed articles and other professional studies. In studies comparing SHR to other laser hair removal technologies, SHR was found to cause considerably less pain, to be more effective, and leads to no side effects in dark skinned patients. The use of SHR in patients with dark skin types may substantially reduce pain or discomfort and minimize severity of blistering, scabbing, crusting and hyper/hyperpigmentation. In addition, little to no prolonged epidermal effects such as redness and inflammation of epidermis, and no downtime before (no topical anesthesia) or after treatment makes the SHR more comfortable and safer than traditional laser systems. Photos courtesy: Tania Meneghel, MD, Dermatologist, São Paulo, Brazil White Paper by Dr. Tania Meneghel, Renaissance Clinic, São Paulo, Brazil SHR is virtually not painful due to the excellent isolation of the thermal effects in the tissue surrounding the follicle. The use of low fluences and relatively long pulses with high repetition frequency, together with a skin surface aircooling, result in a well-tolerated treatment by patients, particularly those with dark phototypes White Paper by Dr. Fernando Urdiales, Miramar Instituto Medico, Málaga, Spain Photos courtesy of : Kyle Holmes, MD, USA Treatment with SHR is considerably less painful than with the Lightsheer. Both diode lasers produced long-term hair reduction in excess of 90%...Rapid pulse, constant motion with the low fluence diode laser represents an advance in safety, efficiency and tolerability of laser hair removal treatment. Peer reviewed article by Dr. Martin Braun, Vancouver Laser and Skin, Vancouver, Canada Treatment with SHR is considerably less painful than with the Lightsheer. Long-term clinical study by Dr. Christopher Zachary, Department Chair, University of Califonia, Irvine, USA 12-13

8 Listen to the Experts Christopher Zachary, MD Department Chair, University of Califonia, Irvine, USA There is significantly less pain using Soprano SHR compared to the Duet. Martin Braun, MD Vancouver Laser Center, Vancouver, BC, Canada I believe SHR is the first innovation in laser hair removal in the past 10 years. We are now able to treat all skin types safely, with less pain. Fernando Urdiales, MD Director of Miramar Medical Institute, Malaga, Spain Soprano XL SHR has revolutionized medical photoepilation, contributing longer lasting and better results compared to conventional technologies. IN-Motion treatment, applying low fluences at high repetition rates, enables us to provide customized photoepilation for each patient. Soprano XL works with all skin and hair types, all year round, with consistent, safe, reliable results. Today Soprano XL SHR is an essential tool for aesthetic practices, providing more patient advantages than any of its competitors. Patrick Bowler, MS.BS Co-Found of the British Association of Cosmetic Doctors Court House Clinics, UK Pain-free isn t the only innovation, of course. SopranoXL also has the fastest coverage rate in the industry, with a huge 12x10 mm spot and up to 10 Hz repetition rate. Plus, with no consumables, Soprano XL is easy to operate and very cost-effective. Soprano XL painless hair removal has transformed the laser hair experience for men because lets face it - men are not very good with pain! Treatment is also quick and results rapid and this is very appealing to male clients. Tania Meneghel, MD, Dermatologist Renaissance Clinic, São Paulo, Brazil The use of SHR in patients with dark skin types may substantially reduce pain or discomfort and minimize severity of blistering, scabbing, crusting and hyper/hyperpigmentation.

9 Alma Lasers is the leading supplier of innovative medical aesthetic technologies. Alma Lasers is recognized by industry practitioners for its whole-hearted commitment to providing complete solutions to professional practices. Alma Lasers offers innovative technologies, dependable equipment, knowledgeable sales staff, and years of industry expertise. We seek the creation of a strong and lasting relationship with our doctors and aesthetic clinics based on trust and a genuine desire for the success of the practice Alma Lasers, Ltd. All rights reserved. Alma Lasers Ltd., its logo, Soprano XL, Harmony XL, Pain-Free, Hair-Free and IN-Motion are trademarks or registered trademarks of Alma Lasers, Ltd. Product specifications are subject to change without notice. Connect with Alma Lasers US Headquarters 485 Half Day Road Suite 100 Buffalo Grove, IL Tel Fax marketing@almalasers.com Headquarters 14 Halamish Caesarea Industrial Park Caesarea, Israel Tel Fax info@almalasers.com PBSH Rev.2

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