Mental Health and Allied Services Formulary

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1 Medicine Class Medicine Formulation Related NICE Technology Appraisal ANXIOLYTICS & HYPNOTICS Beta-blockers Propranolol tablet 10, 40 Z Medicines *Zopiclone (first line) tablet 3.75, 7.5 *TA077 Insomnia newer hypnotic drugs. *Zolpidem tartrate (second line) tablet 5, 10 Zaleplon, zolpidem and zopiclone for the shortterm management of insomnia *Zaleplon (second line) Capsule 5, 10 Chloral and Derivatives Chloral hydrate mixture 500 / 5 ml Chloral betaine tablet 707 Clomethiazole Clomethiazole base capsule 192 Clomethizole edisilate syrup 250 / 5 ml Antihistamines Promethazine hydrochloride tablet 10, 25 elixir 5 / 5 ml Melatonin Circadin Tablets, m/r, melatonin 2 BioMelatonin Tablets, 3 (normal release) Benzodiazepines Diazepam tablet 2, 5, 10 liquid 2 / 5 ml, 5 / 5 ml rectal tubes (=rectal solution) 5, 10 injection emulsion 5 / ml (Diazemuls ) Chlordiazepoxide capsule 5, 10 Lorazepam tablet 1 injection 4 / ml Oxazepam tablet 10, 15 Clonazepam (unlicensed use) tablet 500 micrograms, 2 liquid 500 microgram/ 5mL; 2 / 5mL (ULM) Nitrazepam tablet 5 Loprazolam tablet 1 Lormetazepam tablet 500 micrograms, 1 Temazepam tablet 10, 20 Midazolam oromucosal solution, 5 / ml Diazepam rectal tubes (=rectal solution) 2.5, 5, 10

2 Buspirone Buspirone hydrochloride tablet 5, 10 ANTIPSYCHOTIC MEDICINES Typical - antipsychotics Chlorpromazine hydrochloride tablet 25, 50, 100 oral solution 25 / 5mL, 100/ 5mL Flupentixol dihydrochloride Haloperidol Sulpiride Trifluoperazine hydrochloride Zuclopenthixol dihydrochloride Pimozide Promazine hydrochloride Zuclopenthixol acetate (Clopixol Acuphase ) The injection should NOT be used. tablet 3 capsule 500 micrograms tablet 500 micrograms, 1.5, 5, 10 liquid 1/ ml, 2/ ml injection 5/ ml tablet 200, 400 oral solution 200/ 5mL tablet 1, 5 solution 5 / 5 ml tablet 2, 10, 25 tablet 4 tablet 25, 50 oral solution 25 / 5 ml injection 50/ 1mL, 100 / 2mL Atypical antipsychotics Amisulpride tablet 50, 100, 200, 400 liquid 100 /ml *Aripiprazole tablet 5, 10, 15 orodispersible tablets 10, 15 injection 7.5 /ml (1.3ml (9.75 ) vial) Risperidone tablet 500 micrograms, 1, 2, 3, 4, 6 orodispersible tablet 500 micrograms, 1, 2, 3, 4 liquid 1/ ml Olanzapine tablet 2.5, 5, 7.5, 10, 15, 20 orodispersible tablet 5, 10, 15, 20 injection (Zyprexa ) 5 / ml (10 vial) *Schizophrenia - aripiprazole (TA213) in people aged 15 to 17 years. *Bipolar I disorder aripiprazole (TA292) in adolescents aged 13 years and older

3 Depot Antipsychotics typical Depot Antipsychotics - atypicals Quetiapine tablet 25, 100, 150, 200, 300 XL tablets 50, 200, 300, 400 Clozapine tablet 25, 100 Liquid Flupentixol decanoate injection 20/ ml, 40/ 2mL injection (Depixol conc ) 50/ 0.5 ml, 100/ ml injection (Depixol Low Volume ) 200/ ml Fluphenazine decanoate injection 12.5 / 0.5mL, 25 / 1mL injection (Modecate conc ) 50 / 0.5mL, 100 / 1mL Haloperidol decanoate injection 50 / ml, 100 / ml Pipotiazine palmitate injection 50 / 1mL, 100 / 2mL Zuclopenthixol decanoate injection 200 / ml injection (Clopixol conc ) 500 / ml Paliperidone palmitate depot injection 50, 75, 100, 150 ANTIMANIC MEDICINES Antipsychotics Haloperidol, aripiprazole, olanzapine, quetiapine risperidone Benzodiazepines Diazepam, chlordiazepoxide, lorazepam, oxazepam, clonazepam Lithium Lithium carbonate tablet (Priadel ) 200, 400 Lithium citrate liquid (Li-liquid ) 509 /5 ml liquid (Priadel ) 520 /5 ml Valproic acid Sodium valproate (first line) tablet crushable 100 tablet e/c 200, 500 tablet MR 200, 300, 500 liquid 200 / 5 ml *Semisodium valproate (second line) tablet e/c 250, 500

4 Carbamazepine Carbamazepine tablets 100, 200, 400 tablet MR 200, 400 liquid 100 / 5mL Lamotrigine Lamotrigine tablets 25, 50, 100, 200 dispersible tablets 5, 25, 100 ANTIDEPRESSANT MEDICINES Tricyclics antidepressants Related Antidepressants Amitriptyline hydrochloride Dosulepin (dothiepin) hydrochloride Less suitable for prescribing 1 Clomipramine hydrochloride Imipramine hydrochloride Lofepramine tablet 10, 25, 50 liquid 25 / ml capsule 25 tablet 75 capsule 10, 25, 50 tablet 10, 25 tablet 70 liquid 70 / 5mL Nortriptyline tablet 10, 25 Trimipramine tablet 10, 25 capsules 50 Mianserin hydrochloride tablet 10, 20, 30 Trazodone hydrochloride capsule 50, 100 tablet 150 liquid 50 / ml MAOIs Phenelzine tablet 15 Reversible MAOIs Moclobemide tablet 150, 300 SSRIs Citalopram hydrobromide tablet 10, 20, 40 Citalopram hydrochloride Escitalopram - restricted use Fluoxetine Fluvoxamine Paroxetine Sertraline liquid (Cipramil oral drops) 40 / ml tablet 5, 10, 20 capsule 20 liquid 20 / 5 ml tablet 50, 100 tablet 10, 20, 30 liquid 10 / ml tablet 50, 100

5 Presynaptic 2- adrenoceptor blocker Mirtazapine tablet 15, 30, 45 orodispersible tablet 15, 30, 45 Selective noradrenaline Reboxetine tablet 4 reuptake inhibitor Serotonin and noradrenaline re-uptake Venlafaxine tablet 37.5, 75 capsule XL 75, 150 inhibitor Antiepileptic Pregabalin Capsules, 25, 50, 75, 100, 150, 200, 225, 300 CNS STIMULATANTS AND MEDICINES USED FOR ADHD CNS Stimulants *Dexamfetamine sulphate tablet 5 *Attention deficit hyperactivity disorder (ADHD) - *Methylphenidate hydrochloride Lisdexamfetamine mesilate tablet 5, 10 (immediate release preparations) Concerta XL tablets [22/78], 18, 27, 36 Equasym XL capsules [30/70], 10, 20, 30 Medikinet XL capsules [50/50], 5, 10, 20, 30, 40 capsule 30, 50, 70 Non-CNS Stimulants *Atomoxetine capsule 10, 18, 25, 40, 60 methylphenidate, atomoxetine and dexamfetamine (review) (TA98). ANTIMUSCARINIC MEDICINES Hyoscine hydrobromide (Scopolamine Hydrobromide) Benzatropine Orphenadrine Procyclidine Trihexyphenidyl (benzhexol hydrochloride) Chewable tablet (Kwells ) 300 micrograms Scopoderm TTS patch 1 / 72 hours injection 1 / ml tablet 50 liquid 50 / 5mL tablet 5 liquid 2.5 / 5 ml injection 5 / 1mL tablet 2, 5 liquid 5 /5 ml

6 MEDICINES USED FOR DEPENDENCE Alcohol Dependence Acamprosate tablet 333 Disulfiram tablet 200 Chlordiazepoxide capsule 5, 10 Oxazepam, diazepam and See section lorazepam Naltrexone Tablet 50 Nalmefene restricted use Tablet 18 Baclofen tablets 10 Medicines for Opioid Dependence Medicines for Cigarette Smoking Cessation Methadone oral solution 1 / ml sugar-free oral solution DTF 1/ ml oral solution 10 / ml restricted use injection 10 / ml, 50 / ml restricted use tablet 5 off label Buprenorphine tablet sublingual 400 micrograms, 2, 8 (Subutex ) Buprenorphine/ naloxone tablet sublingual 2 / 500 micrograms, 8 / 2 (Suboxone ) Lofexidine tablet 200 micrograms *Drug misuse - methadone and buprenorphine (TA114) Naltrexone tablet 50 Drug misuse - naltrexone (TA115) Diamorphine injection injection 10, 30 Bupropion (Zyban ) tablet 150 Smoking cessation - varenicline (TA123) Varenicline (Champix ) Tablet 500 micrograms, 1 Nicotine: gum, lozenges, Nicorette Patches (5, 10, 15 ) sublingual tablets, inhalator Nicotinell Patches ( 10, 20, 30 ) and patches Nicorette Gum various flavours (2, 4 ); Nicotinell Chewing gum various flavours (2, 4 ) Nicorette Inhalator (10 per cartridge) MEDICINES USED IN DEMENTIA

7 Acetylcholinesterase inhibiting Medicines *Donepezil hydrochloride *Galantamine *Rivastigmine Glutamate receptor *Memantine antagonist MEDICINES USED IN STATUS EPILEPTICUS tablet 5, 10 tablet orodispersible 5, 10 tablet 8, 12 capsules MR 8, 16, 24 solution 4 / ml capsules 1.5, 3, 4.5, 6 solution 2 /ml patch 4.6 / 24 hours, 9.5 / 24 hours Tablets, 10, 20 Solution 5 / actuation (10/ ml) Benzodiazepines Midazolam oromucosal solution, 5 / ml Diazepam rectal tubes (=rectal solution) 2.5, 5, 10 MEDICINES USED FOR ERECTILE DYSFUNCTION Phosphodiesterase Sildenafil citrate tablet (Viagra ) 25, 50, 100 type-5 inhibitors Tadalafil tablet (Cialis ) 10, 20 Vardenafil tablet (Levitra ) 5, 10, 20 *Alzheimer's disease - donepezil, galantamine, rivastigmine and memantine (TA217).

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