What are the best treatments?
|
|
- Jean Berry
- 7 years ago
- Views:
Transcription
1 What are the best treatments? Description of Condition Depression is a common medical condition with a lifetime prevalence in the United States of 15% among adults. Symptoms include feelings of sadness, hopelessness, or guilt; diminished interest or pleasure in usual activities; decreased ability to think or concentrate; and disruptions in sleep or appetite. Clinically important depression is also known as major depressive disorder, which differs from ordinary sadness. The diagnosis is based on the presence of characteristic symptoms that are sufficient to interfere with functioning or wellbeing, which occur most days for 2 weeks or more. Depression tends to come in episodes, usually lasting for months, which may resolve spontaneously. However, recurrence is common: there is a 60% chance of remission after one episode, 70% after two episodes. Nonprescription Interventions and When to Seek Help The major treatment options for depression are psychotherapy and antidepressant medications. Other options include the herbal preparation known as St. John s wort (Hypericum perforatum) for cases of mild depression, and electroconvulsive therapy, which has been shown to be relatively safe and effective for cases of severe, refractory depression. There is some evidence that aerobic exercise reduces the symptoms of depression and may help to prevent relapse, particularly in elderly persons. Not all forms of psychotherapy (talk therapy) have been shown to be effective in the treatment of depression. However, cognitive behavioral therapy, problem-solving therapy, and interpersonal psychotherapy are of established benefit and may be considered first-line treatments for outpatients with mild-to-moderate depression. Because depression is potentially debilitating and highly treatable, patients with depressed mood or other characteristic symptoms lasting 2 weeks or longer should seek professional advice. Patients with severe symptoms or persistent suicidal thoughts should obtain immediate psychiatric attention. Categories of Prescription Pharmaceutical Treatments (i.e., Drug Classes) The major drug classes available for the treatment of depression are the first-generation antidepressants (e.g., amitriptyline, imipramine, nortriptyline) and the newer, second-generation antidepressants (e.g., fluoxetine, sertraline, venlafaxine). Both first- and second-generation drugs treat depression effectively, although the second-generation agents are associated with fewer side effects and a lower risk of suicide when taken in overdose. Another group of first-generation antidepressants, monoamine oxidase inhibitors, are rarely used in general practice because of drug-drug and drug-food interactions. The relative costs of firstand second-generation antidepressants and other treatments are shown in the Table. Intraclass Comparisons Overall treatment effects among the second-generation antidepressants appear similar. Differences, where they exist, are relatively minor: Mirtazapine may have a faster onset of action than fluoxetine, paroxetine, and sertraline. Based on limited data, venlafaxine may be associated with a higher response rate than fluoxetine and sertraline. Page 1
2 Second-generation antidepressants are similar in terms of overall tolerability and safety. Differences in side-effect profiles are relatively minor but may be clinically important in some patients: Bupropion and nefazodone may be associated with fewer sexual side effects as compared with other second-generation antidepressants. However, nefazodone is no longer a first-line agent owing to concerns about liver toxicity (approximately one case of severe liver failure or death per 250,000 patient-years of exposure). Compared with other second-generation antidepressants, venlafaxine may cause more nausea and be associated with an increased risk of seizures in overdose. Mirtazapine and paroxetine may lead to greater weight gain as compared with bupropion, fluoxetine, and sertraline. The likelihood that sudden cessation of antidepressant therapy will lead to withdrawal symptoms (including dizziness, nausea, paresthesias, and headache) is inversely related to the half-life of the drug. Paroxetine is more often associated with withdrawal symptoms than are sertraline and fluoxetine. In general, second-generation antidepressants appear to have similar efficacy and side effects in the elderly and younger adults. The use of antidepressants in children and adolescents is controversial. A black box warning cautions that in short-term studies antidepressants increased the risk of suicidal thinking and behavior among patients in this age group. Ethnic differences in the effectiveness and safety of second-generation antidepressants have not been adequately studied. First- and second-generation antidepressants taken during pregnancy have not been associated with an increased risk of major congenital malformation. However, information on the long-term neurobehavioral effects of these medications is limited, and withdrawal syndromes among infants have been observed. Based on pharmacokinetic studies and clinical follow-up, nortriptyline, paroxetine, and sertraline may be the preferred choices in women who breast-feed. Interclass Comparisons Psychotherapy (especially cognitive behavioral therapy, problem-solving therapy, and interpersonal psychotherapy) and antidepressant medications are both effective first-line treatments for patients with mild-moderate depression. Cognitive behavioral therapy and second-generation antidepressants are equally effective in the shortterm treatment of postpartum depression. The combination of psychotherapy plus an antidepressant medication is more effective than either alone in patients with severe depression. Neither pharmacotherapy nor psychotherapy act immediately to reduce the symptoms of depression. Both take several weeks or more for maximal effect. Page 2
3 Conclusions Clinically important depression is common and treatable. Second-generation antidepressants and certain forms of psychotherapy are safe and effective treatments for adults with mild-moderate depression. Prolonged treatment (6 months or more) is necessary to reduce the risk of relapse. Methods Note This scientific reference guide is a product of the Prescription Drug Information Project, a collaborative venture between the University of California and the California HealthCare Foundation. This summary is based on a report on the effectiveness and safety of second-generation antidepressants performed by the Drug Effectiveness Review Project (DERP). The DERP report is based on a rigorous method of systematic literature reviews, ensuring inclusion of relevant studies of high quality. Another team of researchers, at the University of California (UC), Davis, prepared a supplementary report on other drug and nondrug treatments for depression. Both reports (DERP and UC Davis) were reviewed by two outside experts and subsequently evaluated by a panel of highly regarded physicians and pharmacists from the University of California. These reports are available at Page 3
4 Relative Costs of First- and Second Generation Antidepressants and Other Treatments Drug Name (generic) Cost + Low ($1-50) Medium ($51-100) High ($101 +) First Generation Tricyclic and tetracyclic agents Amitriptyline* $11 Amoxapine* $36 Clomipramine* $40 Desipramine* $22 Doxepin* $10 Imipramine* $10 Tofranil-PM (Imipramine pamoate) $175 Maprotiline* $31 Nortriptyline* $13 Trazodone* $21 Surmontil (Trimipramine) $118 MAOIs Isocarboxazid Marplan $25 Phenelzine Nardil $40 Tranylcypomine Parnate $50 Second Generation SSRIs/SNRIs Bupropion* $67 Wellbutrin SR (Bupropion SR) $120 Wellbutrin XL (Bupropion XL) $110 Celexa (Citalopram) $72 Cymbalta (Duloxetine) $99 *Generic + Approximate Cost Per One Month Supply. MAOI, monoamine oxidase inhibitor; SNRI, selective norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor. Prices are from drugstore.com (February 2005). Page 4
5 Relative Costs of First- and Second Generation Antidepressants and Other Treatments (cont.) Drug Name (generic) Cost + Low ($1-50) Medium ($51-100) High ($101 +) Second Generation (cont.) SSRIs/SNRIs (cont.) Lexapro (Escitalopram) $67 Fluoxetine tablets* $40 Fluoxetine capsules* $16 Prozac weekly (Fluoxetine weekly) $82 Fluvoxamine* $63 Remeron (Mirtazapine) $92 Nefazodone* $45 Paroxetine* $75 Paxil CR (Paroxetine CR) $89 Zoloft (Sertraline) $75 Effexor (Venlafaxine) $55 Effexor XR (Venlafaxine XR) $95 Complementary/Herbal Therapy St. John s wort* $10 *Generic + Approximate Cost Per One Month Supply. MAOI, monoamine oxidase inhibitor; SNRI, selective norepinephrine reuptake inhibitor; SSRI, selective serotonin reuptake inhibitor. Prices are from drugstore.com (February 2005). Page 5
ANTIDEPRESSANT MEDICINES. A GUIDE for ADULTS With DEPRESSION
ANTIDEPRESSANT MEDICINES A GUIDE for ADULTS With DEPRESSION August 2007 FAST FACTS ON ANTIDEPRESSANTS The antidepressants in this guide work for treating depression. Most people can find one that makes
More informationDepression. Medicines To Help You
Medicines To Help You Depression Use this guide to help you talk to your doctor, pharmacist, or nurse about your medicines for depression. The guide lists all of the FDA-approved products now available
More informationMajor Depression. What is major depression?
Major Depression What is major depression? Major depression is a serious medical illness affecting 9.9 million American adults, or approximately 5 percent of the adult population in a given year. Unlike
More informationMedicines for Treating Depression. A Review of the Research for Adults
Medicines for Treating Depression A Review of the Research for Adults Is This Information Right for Me? Yes, if: A doctor or other health care professional has told you that you have depression. Your doctor
More informationRecognition and Treatment of Depression in Parkinson s Disease
Recognition and Treatment of Depression in Parkinson s Disease Web Ross VA Pacific Islands Health Care System What is depression? Depression is a serious medical condition that affects a person s feelings,
More informationTREATING MAJOR DEPRESSIVE DISORDER
TREATING MAJOR DEPRESSIVE DISORDER A Quick Reference Guide Based on Practice Guideline for the Treatment of Patients With Major Depressive Disorder, Second Edition, originally published in April 2000.
More informationClinical Practice Guideline: Depression in Primary Care, Adult 4 Taft Court Rockville, MD 20850 www.mamsi.com
Clinical Practice Guideline: Depression in 4 Taft Court Rockville, MD 20850 www.mamsi.com 40 05 17 035 3/03 Once a primary care patient presents with depressive symptoms, the primary care physician makes
More informationThe Antidepressants: Treating Depression. Comparing Effectiveness, Safety, and Price
The Antidepressants: Treating Depression Comparing Effectiveness, Safety, and Price Our Recommendations Antidepressants can improve the symptoms of depression, but they can also have serious side effects.
More informationPOPULAR DEPRESSION MEDICATIONS
Popular Depression Medications A Helpful Guide to Antidepressant Drugs POPULAR DEPRESSION MEDICATIONS A Helpful Guide to Antidepressant Drugs Popular Depression Medications A Helpful Guide to Antidepressant
More informationAntidepressants. Understanding psychiatric medications. Information for consumers, families and friends. Titles in the.
Titles in the Understanding psychiatric medications series include: Antidepressants Antipsychotics Benzodiazepines Mood Stabilizers Understanding psychiatric medications Antidepressants For more information
More informationMajor Depressive Disorder
Treatment Works Major Depressive Disorder A Patient and Family Guide Developed from the American Psychiatric Association Practice Guidelines 1 What Is Depression? Major depressive disorder, also referred
More informationDepression. Using Antidepressants to Treat. Contents. 2: Our Recommendations. 3: Welcome. 5: What Are Antidepresssants and Who Needs Them?
Using Antidepressants to Treat Depression Comparing Effectiveness, Safety, and Price Contents 2: Our Recommendations 3: Welcome 5: What Are Antidepresssants and Who Needs Them? 9: Choosing an Antidepresssant
More informationDepression Flow Chart
Depression Flow Chart SCREEN FOR DEPRESSION ANNUALLY Assess for depression annually with the PHQ-9. Maintain a high index of suspicion in high risk older adults. Consider suicide risk and contributing
More informationAlgorithm for Initiating Antidepressant Therapy in Depression
Algorithm for Initiating Antidepressant Therapy in Depression Refer for psychotherapy if patient preference or add cognitive behavioural office skills to antidepressant medication Moderate to Severe depression
More information12629 LIBRIUM CHLORDIAZEPOXIDE HCL 12637 LIBRIUM CHLORDIAZEPOXIDE HCL 12645 LIBRIUM CHLORDIAZEPOXIDE HCL 13110 VALIUM DIAZEPAM 13277 VALIUM DIAZEPAM 24406 LITHANE LITHIUM CARBONATE 25836 SURMONTIL TRIMIPRAMINE
More informationMOH CLINICAL PRACTICE GUIDELINES 6/2011 DEPRESSION
MOH CLINICAL PRACTICE GUIDELINES 6/2011 DEPRESSION Executive summary of recommendations Details of recommendations can be found in the main text at the pages indicated. Clinical evaluation D The basic
More informationRemeron (mirtazapine)
Remeron (mirtazapine) FDA ALERT [07/2005] Suicidal Thoughts or Actions in Children and Adults Patients with depression or other mental illnesses often think about or attempt suicide. Closely watch anyone
More informationDepression is a common biological brain disorder and occurs in 7-12% of all individuals over
Depression is a common biological brain disorder and occurs in 7-12% of all individuals over the age of 65. Specific groups have a much higher rate of depression including the seriously medically ill (20-40%),
More informationMember Rights & Responsibilities
Member Rights & Responsibilities Member Rights and Responsibilities Blue KC has updated our Member Rights & Responsibilities to be consistent across all of our HMO and PPO products. Blue KC members have:
More informationDepre r s e sio i n o i n i a dults Yousuf Al Farsi
Depression in adults Yousuf Al Farsi Objectives 1. Aetiology 2. Classification 3. Major depression 4. Screening 5. Differential diagnosis 6. Treatment approach 7. When to refer 8. Complication 9. Prognosis
More informationDEPRESSION IN PRIMARY CARE: An Overview. Jorge R. Petit, MD Quality Health Solutions
DEPRESSION IN PRIMARY CARE: An Overview Jorge R. Petit, MD Quality Health Solutions Topics In this Session Overview Clinical Importance of Depression Types of Depression Phases of Depression Care Collaborative
More informationMAJOR DEPRESSION DURING CONCEPTION AND PREGNANCY: A Guide for Patients and Families
MAJOR DEPRESSION DURING CONCEPTION AND PREGNANCY: A Guide for Patients and Families David A. Kahn, MD, Margaret L. Moline, PhD, Ruth W. Ross, MA, Lee S. Cohen, MD, and Lori L. Altshuler, MD www.womensmentalhealth.org
More informationMajor Depression? BASIC FACTS SYMPTOMS TREATMENTS FAMILIES
W H A T I S Major Depression? BASIC FACTS SYMPTOMS TREATMENTS FAMILIES MENTAL ILLNESS RESEARCH, EDUCATION & CLINICAL CENTERVA DESERT PACIFIC Mental Illness Research, Education and Clinical Center Va Desert
More informationPSYCHOPHARMACOLOGY AND WORKING WITH PSYCHIATRY PROVIDERS. Juanaelena Garcia, MD Psychiatry Director Institute for Family Health
PSYCHOPHARMACOLOGY AND WORKING WITH PSYCHIATRY PROVIDERS Juanaelena Garcia, MD Psychiatry Director Institute for Family Health Learning Objectives Learn basics about the various types of medications that
More informationIf you are not clear about why an antidepressant has been suggested for you, ask your doctor.
Antidepressants Aims of the leaflet This leaflet is for anyone who wants to know more about antidepressants. It discusses how they work, why they are prescribed, their effects and side-effects, and alternative
More informationBrochure More information from http://www.researchandmarkets.com/reports/3050457/
Brochure More information from http://www.researchandmarkets.com/reports/3050457/ Global Depression Therapy & Treatment Market - Depression drugs and devices, Anxiety Disorders, SSRIs, Global Industry
More informationUnipolar Depression Management Protocol
Unipolar Depression Management Protocol All Team Members: Patient Self-Management Education & Support Unipolar depression or Major Depressive Disorder means that the patient feels persistent low mood or
More informationMajor Depression Medication Adherence Tool Kit
Major Depression Medication Adherence Tool Kit Major Depression Medication Adherence Tool Kit One of the keys to successfully managing major depression is medication adherence. VSHP has developed a new
More informationUpdate on guidelines on biological treatment of depressive disorder. Dr. Henry CHEUNG Psychiatrist in private practice
Update on guidelines on biological treatment of depressive disorder Dr. Henry CHEUNG Psychiatrist in private practice 2013 update International Task Force of World Federation of Societies of Biological
More informationClinical Guideline / Formulary Document Pharmacy Department Medicines Management Services
Clinical Guideline / Formulary Document Pharmacy Department Medicines Management Services DEPRESSION Pharmacological Treatment of Depression NICE guidelines suggest the following stepped care model also
More informationWhy are antidepressants used to treat IBS? Some medicines can have more than one action (benefit) in treating medical problems.
The Use of Antidepressants in the Treatment of Irritable Bowel Syndrome and Other Functional GI Disorders Christine B. Dalton, PA-C Douglas A. Drossman, MD What are functional GI disorders? There are more
More informationMood Disorders. What Are Mood Disorders? Unipolar vs. Bipolar
Mood Disorders What Are Mood Disorders? In mood disorders, disturbances of mood are intense and persistent enough to be clearly maladaptive Key moods involved are mania and depression Encompasses both
More informationCLASSES OF MEDICATION FOR DEPRESSION AND KEY COUNSELING POINTS
CLASSES OF MEDICATION FOR DEPRESSION AND KEY COUNSELING POINTS Release Date: 10/18/2011 Expiration Date: 10/18/2012 FACULTY: Kathleen S. Allen, APMHCNS-BC, DNP FACULTY AND ACCREDITOR DISCLOSURE STATEMENTS:
More information1. Which of the following SSRIs requires up to a 5-week washout period because of the
1 Chapter 38. Major Depressive Disorders, Self-Assessment Questions 1. Which of the following SSRIs requires up to a 5-week washout period because of the long half-life of its potent active metabolite?
More informationDrug Class Review Drugs for Fibromyalgia
Drug Class Review Drugs for Fibromyalgia Final Original Report April 2011 The Agency for Healthcare Research and Quality has not yet seen or approved this report. The purpose of the is to summarize key
More informationDepression in Older Adults A Guide for Patients and Families
The Expert Consensus Guideline Series Depression in Older Adults A Guide for Patients and Families Reprinted from: Alexopoulos GS, Katz IR, Reynolds CF III, Carpenter D, and Docherty JP. The Expert Consensus
More informationdepression & medication
depression & medication LAURA PINSKY, LCSW COLUMBIA UNIVERSITY, CPS Depression and Medication Laura Pinsky, LCSW Columbia University Counseling and Psychological Service What is depression? In the language
More informationDepression: A Guide for Patients and Families
Depression: A Guide for Patients and Families CO-MED is a research study funded by contract N01-MH-90003-02 to the University of Texas Southwestern Medical Center at Dallas from the National Institute
More informationTreating Major Depressive Disorder
Treating Major Depressive Disorder A Quick Reference Guide Based on Practice Guideline for the Treatment of Patients With Major Depressive Disorder, Third Edition, originally published in October 2010.
More informationUnderstanding Major Depression and Recovery
Understanding Major Depression and Recovery What you need to know about this medical illness Major depression is a medical illness that affects thoughts, feelings, behavior, mood and physical health. Introduction
More informationDepression (major depressive disorder)
Diseases and Conditions Depression (major depressive disorder) By Mayo Clinic Staff Depression is a mood disorder that causes a persistent feeling of sadness and loss of interest. Also called major depressive
More informationEvidence-based best practice interventions for the treatment of mood disorders: Annotated Information Package
Evidence-based best practice interventions for the treatment of mood disorders: Annotated Information Package September 2007 Evidence-based best practice interventions for the treatment of mood disorders:
More informationDEPRESSION DURING THE TRANSITION TO MENOPAUSE: A Guide for Patients and Families
DEPRESSION DURING THE TRANSITION TO MENOPAUSE: A Guide for Patients and Families David A. Kahn, MD, Margaret L. Moline, PhD, Ruth W. Ross, MA, Lori L. Altshuler, MD, and Lee S. Cohen, MD www.womensmentalhealth.org
More informationPsychiatric Medications: Pearls and Pitfalls. The majority of medications used in patients with psychiatric diagnoses have more than one use.
Psychiatric Medications: Pearls and Pitfalls Rule #1 The majority of medications used in patients with psychiatric diagnoses have more than one use. Without access to the patient s medical record, to review
More informationWellbutrin (bupropion)
Wellbutrin (bupropion) FDA ALERT [09/2007] - Suicidality and Antidepressant Drugs Antidepressants increased the risk compared to placebo of suicidal thinking and behavior (suicidality) in children, adolescents,
More informationwww.mooddisorderscanada.ca 1
1 Table of Contents 3 What is Depression? 4 What Are the Symptoms Like? 6 Are There Different Types of Depression? 8 What Causes Depression? 11 Experiencing Stigma 12 Depression in The Workplace 13 Recovery
More informationMental Health Medications
Mental Health Medications National Institute of Mental Health U.S. DEPARTMENT OF HEALTH AND HUMAN SERVICES Contents Mental Health Medications..............................................................1
More informationAntidepressant Choices in Primary Care: Which to Use First?
Antidepressant Choices in Primary Care: Which to Use First? Sherri Hansen, MD Doctor Hansen is a clinical assistant professor with the University of Wisconsin Medical School. Please address correspondence
More informationmaking sense of antidepressants making sense antidepressants
making sense of antidepressants making sense antidepressants Making sense of antidepressants This booklet is for anyone who wants to know more about antidepressants. It explains what antidepressants are,
More informationDepression: A Guide for Patients and Families
Depression: A Guide for Patients and Families 1 Depression: A Guide for Patients and Families If you or someone you know has been diagnosed with depression, you may have some questions. This guide is intended
More informationOverview of Mental Health Medication Trends
America s State of Mind Report is a Medco Health Solutions, Inc. analysis examining trends in the utilization of mental health related medications among the insured population. The research reviewed prescription
More informationTOOL KIT FOR THE MANAGEMENT OF ADULT POSTPARTUM DEPRESSION
TOOL KIT FOR THE MANAGEMENT OF ADULT POSTPARTUM DEPRESSION TOOL KIT FOR THE MANAGEMENT OF ADULT POSTPARTUM DEPRESSION The clinical tool kit is intended to assist the PCP in assessing the postpartum needs
More informationCLINICAL PRACTICE GUIDELINES. Depression
CLINICAL PRACTICE GUIDELINES Depression MOH Clinical Practice Guidelines 6/2011 3 1 Published by Ministry of Health, Singapore 16 College Road, College of Medicine Building Singapore 169854 Printed by
More informationDepression. Depress EPRESSION. Depression
Depress EPRESSION Depression Depression DEPRESSION Most people feel depressed at times. Losing a loved one, getting fired from a job, going through a divorce, and other difficult situations can lead a
More informationIMR ISSUES, DECISIONS AND RATIONALES The Final Determination was based on decisions for the disputed items/services set forth below:
Case Number: CM13-0018009 Date Assigned: 10/11/2013 Date of Injury: 06/11/2004 Decision Date: 01/13/2014 UR Denial Date: 08/16/2013 Priority: Standard Application Received: 08/29/2013 HOW THE IMR FINAL
More informationTreatments for Major Depression. Drug Treatments The two (2) classes of drugs that are typical antidepressants are:
Treatments for Major Depression Drug Treatments The two (2) classes of drugs that are typical antidepressants are: 1. 2. These 2 classes of drugs increase the amount of monoamine neurotransmitters through
More informationAntidepressants in Pregnancy D R S N E H A P A R G H I
Antidepressants in Pregnancy D R S N E H A P A R G H I Overview Depression and its effects Antidepressants and their effects Birth defects Miscarriage Neonatal withdrawal Longterm consequences Breastfeeding
More informationPharmacotherapy of BPSD. Pharmacological interventions. Anti-dementia drugs. Abhilash K. Desai MD Medical Director Alzheimer s Center of Excellence
Pharmacotherapy of BPSD Abhilash K. Desai MD Medical Director Alzheimer s Center of Excellence Pharmacological interventions Reducing medication errors. Reducing potentially inappropriate medication prescription.
More informationHow to Identify and Diagnose Depression
Depression Spirella Building, Letchworth, SG6 4ET 01462 476700 www.mstrust.org.uk reg charity no. 1088353 Depression and MS Date of issue: March 2010 Review date: March 2011 Contents Introduction 2 1.
More informationNew Patient Information. Address: City: State: Zip: Ph#: Cell#:
Patient Information: Last Name: New Patient Information First Name: Address: City: State: Zip: Ph#: Cell#: S.S.N: Email: May we contact you by email? Yes No Date of Birth: May we send you information about
More informationAntidepressant treatment in adults
Antidepressant treatment in adults A NICE pathway brings together all NICE guidance, quality standards and materials to support implementation on a specific topic area. The pathways are interactive and
More informationTreatment of Patients With Major Depressive Disorder Second Edition
PRACTICE GUIDELINE FOR THE Treatment of Patients With Major Depressive Disorder Second Edition WORK GROUP ON MAJOR DEPRESSIVE DISORDER T. Byram Karasu, M.D., Chair Alan Gelenberg, M.D. Arnold Merriam,
More informationTreatment Modalities As in younger patients, the goals of treating depression in elderly patients include alleviating
Iranian Rehabilitation Journal, Vol. 10, No. 16, Oct. 2012 Reviews/Short communication Treatment of Depression in the Elderly: A systematic review Arash Mirabzadeh, MD. University of Social Welfare and
More informationDepression (major depression)
Reprints A single copy of this article may be reprinted for personal, noncommercial use only. Depression (major depression) By Mayo Clinic staff Original Article: http://www.mayoclinic.com/health/depression/ds00175
More informationNICE Clinical guideline 23
NICE Clinical guideline 23 Depression Management of depression in primary and secondary care Consultation on amendments to recommendations concerning venlafaxine On 31 May 2006 the MHRA issued revised
More informationPharmacologic Treatment of Acute Major Depression and Dysthymia
POSITION PAPERS CLINICAL GUIDELINE, PART 1 Pharmacologic Treatment of Acute Major Depression and Dysthymia Vincenza Snow, MD; Steven Lascher, DVM, MPH; and Christel Mottur-Pilson, PhD, for the American
More informationMedication Management of Depressive Disorders in Children and Adolescents. Satya Tata, M.D. Kansas University Medical Center
Medication Management of Depressive Disorders in Children and Adolescents Satya Tata, M.D. Kansas University Medical Center First Line Medications SSRIs Prozac (Fluoxetine): 5-605 mg Zoloft (Sertraline):
More informationDepression in Long-Term Care
Depression in Long-Term Care Annette Carron, DO, CMD, FACOI, FAAHPM Director Geriatrics and Palliative Care Botsford Hospital Slide 1 OBJECTIVES Know and understand: Incidence and morbidity of depressive
More informationAntidepressants and suicidal thoughts and behaviour. Pharmacovigilance Working Party. January 2008
Antidepressants and suicidal thoughts and behaviour Pharmacovigilance Working Party January 2008 PhVWP PAR January 2008 Page 1/15 1. Introduction The Pharmacovigilance Working Party has on a number of
More informationTreatment Resistant Depression
Upon completion of this seminar the professional will be expected to demonstrate knowledge and: Sophia F. Dziegielewski, Ph.D., LCSW Identify important terms, myths and practices related to the treatment
More informationTreatment and management of depression in adults, including adults with a chronic physical health problem
Issue date: October 2009 Depression Treatment and management of depression in adults, including adults with a chronic physical health problem This is an update of NICE clinical guideline 23 Developed by
More informationNICE clinical guideline 90
Depression in adults The treatment and management of depression in adults Issued: October 2009 NICE clinical guideline 90 guidance.nice.org.uk/cg90 NHS Evidence has accredited the process used by the Centre
More informationTaking SSRI Antidepressants During Pregnancy: Considerations and Risks
Taking SSRI Antidepressants During Pregnancy: Considerations and Risks For pregnant women or women contemplating pregnancy, reading literature about depression, pregnancy and medication often leaves them
More informationAn Investigation of Atypical Antidepressants
An Investigation of Atypical Antidepressants An Interactive Qualifying Project Report submitted to the Faculty of WORCESTER POLYTECHNIC INSTITUTE in partial fulfillment of the requirements for the Degree
More informationObserver extra: Depression
Observer extra: Depression An internist s guide to screening, diagnosing and treating clinical depression. 2 Observer extra: Depression An initial approach to diagnosing and treating depression Depression
More informationDepression Treatment Guide
Depression Treatment Guide DSM V Criteria for Major Depressive Disorders A. Five (or more) of the following symptoms have been present during the same 2-week period and represent a change from previous
More informationMedications A detailed booklet that describes mental disorders and the medications for treating them includes a comprehensive list of medications.
A detailed booklet that describes mental disorders and the medications for treating them includes a comprehensive list of medications. 2014 Contents Introduction: Mental Health Medications...1 What are
More informationBest Practices Treatment Guideline for Major Depression
Best Practices Treatment Guideline for Major Depression Special Report on New Depression Treatment Technology Based on 2010 APA Practice Guidelines Best Practices Guideline for the Treatment of Patients
More informationAmendments to recommendations concerning venlafaxine
Amendments to recommendations concerning venlafaxine On 31 May 2006 the MHRA issued revised prescribing advice for venlafaxine*. This amendment brings the guideline into line with the new advice but does
More informationIntroduction to Child & Adolescent Psychiatry
Introduction to Child & Adolescent Psychiatry Psychiatry Clerkship Lecture Todd Peters, MD Assistant Professor, Department of Psychiatry Division of Child and Adolescent Psychiatry Master Clinical Teacher,
More informationDepression: Assessment and Evidenced Based Treatments
Depression: Assessment and Evidenced Based Treatments By: Jennifer Layden, LCSW, LMFT APP0109 (8/12) Statistics on Depression? Depression is the leading cause of disability world wide (2005-2006) In this
More informationClinical guideline Published: 28 October 2009 nice.org.uk/guidance/cg90
Depression in adults: recognition and management Clinical guideline Published: 28 October 2009 nice.org.uk/guidance/cg90 NICE 2009. All rights reserved. Last updated April 2016 Your responsibility The
More informationDepression in adults with a chronic physical health problem
Depression in adults with a chronic physical health problem Treatment and management Issued: October 2009 NICE clinical guideline 91 guidance.nice.org.uk/cg91 NICE has accredited the process used by the
More informationDepression in the Elderly: Recognition, Diagnosis, and Treatment
Depression in the Elderly: Recognition, Diagnosis, and Treatment LOUIS A. CANCELLARO, PhD, MD, EFAC Psych Professor Emeritus and Interim Chair ETSU Department of Psychiatry & Behavioral Sciences Diagnosis
More informationThe Pharmacological Management of Depression in the Adult Person with Mental Retardation and Developmental Disabilities (MR/DD)
The Pharmacological Management of Depression in the Adult Person with Mental Retardation and (MR/DD) 1. Overview Multiple classes of medications are available for treatment of depression in the patient
More informationTREATMENT-RESISTANT DEPRESSION AND ANXIETY
University of Washington 2012 TREATMENT-RESISTANT DEPRESSION AND ANXIETY Catherine Howe, MD, PhD University of Washington School of Medicine Definition of treatment resistance Failure to remit after 2
More informationDepression and Anxiety in Parkinson s disease
Depression and Anxiety in Parkinson s disease Greg Pontone, MD Director, Movement Disorders Psychiatry Clinical Programs at Johns Hopkins Morris K. Udall Parkinson's Disease Research Center Johns Hopkins
More informationDepressive Disorder. Aetiology The causes of depressive disorder can be classified into biological and psychosocial factors.
Depressive Disorder Definition Depression is a major psychiatric illness characterised by 3 main symptoms namely Low mood Loss of interest / loss of ability to experience pleasure (anhedonia) Excessive
More informationPerspective Depression and Adjustment Disorder in Patients With HIV Disease
Perspective Depression and Adjustment Disorder in Patients With HIV Disease Depressive symptoms are common in patients with HIV disease, reflecting in part the contribution of preexisting depressive illness
More informationThe following is a sample of psychotropic drug warnings that drug regulatory agencies
Chronology of International Drug Regulatory Agency Warnings about Psychotropic Drugs The following is a sample of psychotropic drug warnings that drug regulatory agencies around the world have issued.
More informationAnxiety Disorders Drug Treatment Guidelines
Western Australian Psychotropic Drugs Committee Anxiety Disorders Drug Treatment Guidelines August 2008 www.watag.org.au Table of Contents Executive Summary... 4 Psychological or pharmacological treatment?...
More informationDepression. The treatment and management of depression in adults. This is a partial update of NICE clinical guideline 23
Issue date: October 2009 Depression The treatment and management of depression in adults This is a partial update of NICE clinical guideline 23 NICE clinical guideline 90 Developed by the National Collaborating
More informationPaxil/Paxil-CR (paroxetine)
Generic name: Paroxetine Available strengths: 10 mg, 20 mg, 30 mg, 40 mg tablets; 10 mg/5 ml oral suspension; 12.5 mg, 25 mg, 37.5 mg controlled-release tablets (Paxil-CR) Available in generic: Yes, except
More informationRecognizing and Treating Depression in Children and Adolescents.
Recognizing and Treating Depression in Children and Adolescents. KAREN KANDO, MD Division of Child and Adolescent Psychiatry Center for Neuroscience and Behavioral Medicine Phoenix Children s Hospital
More informationWorkshop: Management of Depression in the Primary Care Setting, Kaiser Permanente of Ohio s Multidisciplinary Model
Workshop: Management of Depression in the Primary Care Setting, Kaiser Permanente of Ohio s Multidisciplinary Model Larissa Elgudin, MD, Chief of Behavioral Health Services Colleen O Malley RN, BSN, Regional
More informationMEDICATION GUIDE WELLBUTRIN (WELL byu-trin) (bupropion hydrochloride) Tablets
MEDICATION GUIDE WELLBUTRIN (WELL byu-trin) (bupropion hydrochloride) Tablets Read this Medication Guide carefully before you start using WELLBUTRIN and each time you get a refill. There may be new information.
More informationDepression. Clinical Background
Guidelines for Clinical Care Ambulatory Depression Guideline Team Team leaders Thomas L Schwenk, MD Family Medicine Linda B Terrell, MD General Medicine Team members R Van Harrison, PhD Medical Education
More information