Inserm Liliane Bettencourt School

Transcription

1 Inserm Liliane Bettencourt School Scientific Directors: Jean-Claude Chottard 1, Philippe Ascher 2, 1 Paris Descartes University, Laboratory of Pharmacological and Toxicological Biochemistry and Chemistry, 2 Paris Descartes University, Laboratory of Cerebral Physiology, Administrative staff from the Inserm Liliane Bettencourt School: Barro Sow Inserm Liliane Bettencourt School Officer Nathalie François Assistant

2 Presentation of the Inserm Liliane Bettencourt School

3 General presentation The Inserm School was founded in It offers fast-track research training for students from across France who have a strong interest in scientific research. Starting in the second year of study in medicine or pharmacy, it allows to obtain an early Master degree and later provides the possibility to obtain an MD- degree. In 2007, it was renamed the Inserm Liliane Bettencourt School thanks to funding from the Fondation Bettencourt Schueller for paying student fellowships.

4 Objective of the training offered by the Inserm Liliane Bettencourt School The program is designed to provide the opportunity to second year students of medicine and pharmacy to complement their clinical studies with a program preparing them for biological and medical research. It leads to a Master 2 degree, and subsequently to a Ph.D. The Master 2 degree must be prepared early in the curriculum, namely before the 4th year of the medical school, and after either the 3rd or 4th year of the pharmacy school. The Ph.D can be prepared either immediately after the Master 2, or later in the curriculum. The ultimate objective of this joint honors course is to enable future physicians and pharmacists to combine their clinical practice with research activity.

5 Diagram of the Inserm Lilian Bettencourt School Medicine track 1 st and2 nd cycle: 6 years 3 rd cycle: 3 to 5 years Normal research course Entrance exam B1 B2 M1 M2 M3 M4 courses + clinical training + M1 TU courses + clinical training National Exam «ECN» Internship M2-R Internship Part time Full time fellowship residency Part time residency 4 years Inserm School course B1 B2 M1 courses + clinical training+ M1 TU 1 st et 2 nd cycle: 7 years M2-R 1 year M2 M3 M4 Internship courses + clinical training+ post master days Full-time M2 3 rd cycle: 3 to 5 years+ 2 to 3 years(thesis) 2 years M3 M4 Full-time fellowship National Exam «ECN» internship Internship 2 years residency 4 years residency Path 1 Path 2 Ecole de Février 6 months research 3 years courses + clinical training 4 years + annual scientific days (in September) + post master days (in March) 1 st and 2 nd cycle: 10 years 3 rd cycle: 3 to 5 years Annual scientific days: presentation of research findings by students (oral and poster presentations) préparation of while assuming clinical responsabilities

6 Diagram of the Inserm Lilian Bettencourt School Pharmacy track Normal research course Inserm Liliane Bettencourt course B1 (1st year of general healthcare studies B1 (1st year of general healthcare studies Ecole de Février of the Inserm School HU * 2 3 M1 research TU + laboratory M1 TU Competitive exam for admission to internship 6-month in a research laboratory M2-R Full-time (3 years) 6 M2-R Competitive exam M2-R for admission to internship 4 5 HU * 4 5 HU * Internship M2-R 4 5 Research internship Internship Annual scientific days September + post master scientific March HU * HU * Internship Medical biology Internship Hospital pharmacy Internship research option Pharmaceutical innovation and research internship Internship Competitive exam for admission to internship & *HU: Year in a teaching hospital 1 Track : with internship 2 Track : without internship

7 How can you enroll in the Inserm Liliane Bettencourt School? Each French Faculty presents a list of students to be included in the School s initial selection. The selection committee asks Deans to examine applications upstream. Deans can hold interviews with students, to best assess their motivation and their ability to contribute to and profit from a course that requires a great deal of personal work. Application-based selection, open to students from across France (~ 50 applications selected) CV cover letter transcript of high school grades and specific honors transcript of grades and rank at the entrance examination of the 2 nd year of medical and pharmacy studies analysis of a recent scientific article The students selected then take part in the 2-week Ecole de février (see pages 10 and 11 for a more detailed description of this course)

8 The Ecole de Février 66 hours of classes 14 full days of training-motivation in residence at the Sèvres International Centre of Educational Studies (CIEP). Mathematical tools applied to biology and medicine 14 hours Physics 19 hours Chemistry 19 and a half hours Biology 14 hours 6 hours of analysis of scientific articles 24 hours of exchanges with teachers 6 conferences given by renowned researchers, capable of inciting enthusiasm in research

9 Ecole de Février program 2012 Physics 1. Molecular transport and diffusion 2. Molecular motors 3. Physics and functions of cellular materials 4. A few detection and decision-making mechanisms in cell biology Chemistry 1. Glycolysis and the respiratory chain. Chemical, physiological and pathological aspects 2. Chemical reactivity in a biological environment 3. Cytochromes P450 Biology Genomes and diseases: contribution of model systems 1. C.elegans 2. Drosophila 3. The zebrafish Mathematical tools applied to biology and medicine 1. Deterministic modeling of dynamic systems 2. Statistical modeling: the likelihood principle and applications in biology and medicine 3. Introduction to analysis of data from micro-array techniques

10 Entrance examination for the Inserm Liliane Bettencourt School The entrance examination is taken every year in June. It is based on two oral exams based on the analysis of documents 1 in biology (compulsory) 1 in either physics, chemistry or mathematical tools (the choice of field is made by the student). This exam is based on material taught in the Ecole de février completed by preparatory documents received 2 months in advance. Assessment focuses on the ability of applicants to use their knowledge in a research-oriented way. Following these exams, about twenty students are selected, the exact number depending on the level of applicants. These students will then be followed up by the whole teaching and administrative team which will help them find the laboratories where they will be initiated to research, and provide financial support.

11 The first 3 years lead to the obtention of a Master degree 1 st year - (in parallel with the 2 nd year of medical or pharmacy studies) Ecole de Février (14 days), Master 1 teaching unit (TU) and entrance examination for the Inserm School 2 nd year 2 nd year - (in parallel with the 3 rd year of medical or pharmacy studies) Master 1 TU, 6 months (or 2 x 3 months) full-time in a research laboratory (Inserm Aviesan). Presentation of the results obtained. 3 rd year - (interruption of the medical or pharmacy curriculum) Master 2 (required for continuing in the School s program).

12 Enrollment in a Master 2 requires 60 ECTS Medical students not belonging to the Inserm School usually only satisfy to these requirements after their sixth year of Medical School 30 ECTS - validation of the sixth year of medical studies 18 ECTS - validation of Master 1 teaching units (equivalent to 2 former MSBM (Master of Biological and Medical Sciences) certificates) 12 ECTS - validation of 2 months of laboratory work completed in Master 1 (2 x 6 ECTS) Medical students of the Inserm School can satisfy to these requirements after their third year of Medical School 6 ECTS - validation of the 2-week Ecole de Février course and passing of the June entrance examination 18 ECTS - validation of Master 1 teaching units in choice 36 ECTS - validation of the 6-month researchperiod in the 3rd year (6 x 6 ECTS) Universities are responsible for assessing the number of ECTS required for enrolling in a Master 2. The proposal above, which corresponds to the procedure adopted by several universities, is given by way of example.

13 The post-master Scientific Sessions A 2- or 3-day meeting attended by 4th to 6th year medical students, doctoral students preparing a and interns. Devoted to a major medical theme chosen by the students, this meeting consists of conferences given by researchers in various disciplines and presentations by the School s students. It provides an opportunity for exchanges between speakers and students of the Inserm School.

14 The Scientific Sessions of September Objective: bring together all of the School s students and welcome newly selected applicants. The students present the research findings that they have obtained in the successive phases of the curriculum 6-month initial laboratory experience Preparation of a Master 2 Preparation of a Participation in research while an intern or extern Research performed during residency,etc. Presentations are made both orally in a plenary session and by posters.

15 Funding from the Fondation Bettencourt Schueller Fellowships for the selected students

16 Student fellowships (*2010/2011 figures) Funding from the Fondation Bettencourt Schueller Medicine track 30 months x 417,09 * Fellowship provided by the EDILB (10 months x 3 years) Research master M2 M3 M4 fellowship internship internship residency + research Path 1 Medicine course and training in research 6 months x 417,09 M1 special agreement provided by the EDILB B1 B2 M Agreement of each faculty 2 nd clinical cycle fellowship 6 to 10 months x 417,09 hospital fellowship 2nd clinical cycle 10 Hospital salary internship + researchresidency + research Hospital salary 36 months x 1684,93 gross Work contract signed between the Inserm DR** and the student 14 traitements hospitalier et universitaire Hospital and university salaries 18 years years Path 2 * (subject to: post-master days, scientific sessions of september, conferences, workshops, laboratory seminar) ** DR: Inserm Regional Delegation salary Training in research: full-time in a laboratory part-time Research practice: while practising a medical activity

17 Student fellowships (*2010/2011 figures) Funding from the Fondation Bettencourt Schueller Pharmacy track 20 months x 417,09 * Fellowship provided by the EDILB (10 months x 2 years) 5 Internship 4 DES1 DES2 DES3 DES4 HU * Inserm School course 6 months x 417,09 Special agreement provided by the EDILB B1 Ecole de Février 2 3 M1 TU 6 monthlaboratory M2-R Full-time (3 years) PhdD fellowships 4 5 HU * 4 5 DES1 DES2 DES3 DES4 4 5 HU * HU * Internship 24 months x 1684,93 gross Work contract signed between the Inserm DR** and the student 6 to 10 months x 417,09 Agreement of each university * (subject to: post-master days, scientific sessions of september, conferences, workshops, laboratory seminar) ** DR: Inserm Regional Delegation salary

18 2011/2012 calendar

19 Calendrier 2011/ 2012 Selection by faculty Deans of applicants for the Inserm School 2011/2012 : Deadline for submission of applications for the school : november 15, P.M École de février 2012: january 29 to February Post-Master days: March 9, 10 and 11, 2012 Entrance examination for the School s 2 nd year : June 13,14, 15, 2012 Scientific days : September 7,8 and 9, 2012

20 Useful contacts

21 The Inserm Liliane Bettencourt coordination team Biochimie Jean Claude CHOTTARD Université Paris Descartes Laboratoire de Chimie et biochimie pharmacologiques et toxicologiques 45, Rue des Saints Pères Paris cedex Philippe ASCHER CNRS UMR 8118 Laboratoire de physiologie cérébrale UFR biomédicale 45, Rue des Saints Pères Paris cedex Olivia REINAUD Université Paris Descartes Laboratoire de Chimie et Biochimie pharmacologiques et toxicologiques 45, Rue des Saints Pères Paris cedex Physique François AMBLARD CNRS - UMR 168 Institut Curie Laboratoire de Physico-Chimie 11, Rue Pierre et Marie Curie Paris [email protected]

22 The Inserm Liliane Bettencourt coordination team Biologie Jean Louis BESSEREAU Inserm - Unité 789 Ecole Normale Supérieure Biologie Cellulaire de la Synapse 46, Rue d'ulm Paris [email protected] Outils mathématiques Jean-Christophe THALABARD Hôtel-Dieu Unité de Gynécologie Endocrinologie 1 Place Parvis Notre Dame Paris cedex [email protected] Serge BIRMAN ESPCI ParisTech, CNRSLaboratoire de neurobiologie 10 rue Vauquelin Paris cedex [email protected] Khashayar PAKDAMAN Institut Jacques Monod Université Paris Diderot - Tour 43 2 Place Jussieu Paris cedex [email protected] Philippe VERNIER CNRS - UPR 2197 Institut de Neurobiologie Alfred FESSARD 1 avenue de la Terrasse Gif sur Yvette cedex (secr) [email protected]

23 The Inserm Liliane Bettencourt coordination team - the selection committee Biochimie Physique Outils mathématiques Damien ALCOR IPMC-CNRS UMR , route des Lucioles VALBONNE [email protected] Jean-Pierre MAHY Université Paris Sud Laboratoire de chimie bio-organique et bio-inorganique ICMO - Bâtiment Orsay [email protected] Isabelle McCORT Université Paris Descartes UMR rue des Saints Pères PARIS CEDEX [email protected] Frédéric BANSE Université Paris Sud UMR8182 Institut de Chimie Moléculaire et des Matériaux d'orsay (ICMMO) 15, rue Georges Clémenceau ORSAY CEDEX [email protected] Laurent BOURDIEU Institut de Biologie de l'ecole Normale Supérieure IBENS, UMR ENS-CNRS-INSERM 8197 Ecole Normale Supérieure 46 rue d'ulm Paris [email protected] Claire WILHELM Université Paris Diderot UMR 7057 Bâtiment Condorcet - CC rue A. Domon et L. Duquet PARIS CEDEX [email protected] Raphaël PORCHER Hôpital Saint-Louis Département de Biostatistique et Informatique Médicale Unité Inserm 717 Biostatistique et épidémiologie clinique 1 avenue Claude Vellepaux Paris cedex [email protected] Grégory NUEL Université Paris Descartes INSMI (Institut des sciences mathématiques et de leurs interactions) UFR de Maths et informatique UMR8145 Mathématiques appliquées 45 rue des Saints Pères PARIS CEDEX [email protected] Pierre-Yves BOELLE Faculté de médecine Saint Antoine Inserm U rue Chaligny Paris cedex [email protected]

24 The Inserm Liliane Bettencourt coordination team - the selection committee Biologie François ROUYER Laboratoire UPR2216 CNRS 1, avenue de la terrasse BATIMENT 33, 3EME ETAGE GIF SUR YVETTE Cedex [email protected] André KLARSFELD Institut de neurobiologie Alfred Fessard - CNRS UPR3294 Neurobiologie et développement (N&D) Gif/Yvette cedex [email protected] Alain CHEDOTAL Centre de Recherche INSTITUT DE LA VISION UMR_S968 Inserm / UPMC / CHNO des Quinze- Vingts 17 rue Moreau PARIS [email protected] Pierre BILLUART Institut Cochin, Dpt GD Inserm U INSTITUT COCHIN 24 rue du Fg St Jacques Paris [email protected] Jamel CHELLY Faculté de médecine -site Cochin Département /U1016 : génétique et développement (gd) 24 rue du faubourg Saint Jacques Paris [email protected] Frédéric ROSA Ecole Normale Supérieure U1024, Institut de biologie de l'ecole Normale Supérieure / CNRS/ UMR , rue D'Ulm Paris cedex [email protected] Alain BESSIS Ecole Normale Supérieure Institut de biologie de l'ecole Normale Supérieure / CNRS/ UMR , rue D'Ulm Paris cedex [email protected] Serge AMSELEM FACULTE DE MEDECINE - SITE ST ANTOINE Institut de recherche en santé (IRS) IFR65 27 RUE CHALIGNY PARIS CEDEX [email protected] Jean-Louis LAPLANCHE Hôpital Lariboisière Service de biochimie et biologie moléculaire 2 rue Ambroise Paré Paris cedex ou [email protected]

25 The Inserm Liliane Bettencourt coordination team within Inserm Nicolas Pesnel Head of the Scientific Training and Support in Research Office +33 (0) (0) Barro Sow Inserm Liliane Bettencourt School Officer 101 rue de Tolbiac Paris cedex (0) (0) Nathalie François Inserm Liliane Bettencourt School Assistant +33 (0) (0)

26 The Association Médecine Pharmacie Sciences Founded by the School s students as a not-for-profit association, AMPS seeks to: foster professional links between students and researchers engaged in the various French programs aiming at combining an early training in science with a medical or pharmacy training give students the possibility to exchange and dialogue promote joint honors courses in Faculties of Medicine and Pharmacy in France structure a network of people driven by the same vision for French biomedical research.

27 Thank you for your attention!