Ana Leite de Almeida Monteiro de Oliveira PhD, Msc, CEng

Transcription

1 CURRICULUM VITAE Ana Leite de Almeida Monteiro de Oliveira PhD, Msc, CEng Nationality Date of birth Place of birth Address PERSONAL DATA Portuguese 03/12/1974 Porto Matosinhos RESEARCH INTERESTS Materials chemistry and processing, polymer and composite materials, ceramic materials, natural-based biodegradable polymers, study of mineralization processes; surface properties, modification and coating; biomaterials and tissue engineering of bone, drug delivery. Presently October to December 2007 October 2004 to March 2005 April to December 2002 October 2001 to January 2002 September 1999 to February 2002 May 1999 October 1998 to April 1999 June 1999 October 1997 to July 1998 CURRENT SITUATION AND MAJOR ACTIVITIES Associate Professor at the Department of Health Sciences, Portuguese Catholic University. Post-Doc Researcher at the 3B s Research Group - Biomaterials, Biodegradables and Biomimetics, Headquarters of the European Institute of Excellence on Tissue Engineering and Regenerative Medicine, University of Minho, Portugal. Visitor Researcher at the Department of Biomaterials of Tufts University, Boston, EUA. PhD Researcher at Consejo Superior de Investigaciones Cientificas (CSIC) em Madrid, Espanha. Developed new Technologies applied to the field of orthopedics in the company DePuy Orthopaedics, Inc. (Johnson & Johnson, Warsaw IN, EUA; Lectured Materials Chemistry to the course of Mechanics Engineering in the Polytechnic Institute of Porto. Master in Science and Engineering of Materials by the University of Minho. The thesis was defended in the field of materials chemistry (biomaterials for orthopedic applications). Started the research team to form the 3B s Research Group - Biomaterials, Biodegradables and Biomimetics ( in the Department of Polymer Engineering, University of Minho. Training period at Clínica Puerta da Hierro and Conselho Superior de Investigação Científica (CSIC) Instituto de Ciência e Tecnologia de Polímeros, in Madrid, oriented by Prof. Júlio San Román and Prof. Rui L. Reis. Degree in Materials Engineering, University of Porto, Portugal Seminar and last year Project in the Biomedical field in the University of Porto and the Institute of Biomedical Engineering (INEB), Porto. PUBLICATIONS AND PARTICIPATIONS IN INTERNATIONAL CONFERENCES AND WORKSHOPS Has 25 publications (14 articles in international journals with peer review and 11 book chapters), all in English. Has participated in different workshops and international conferences where has presented the scientific work and has given several tutorials. Has done 37 international communications from which 14 posters e 25 oral presentations (see pag.3). 1/7

2 Experience Evaluation Reviewing PARTICIPATION IN PROJECTS Identification of new opportunities of financing, preparation of proposals (including budgets) and selection of partners (at the national and international level); contract negotiation, implementation and coordination of projects; writing progress reports (activity, managing and financing reports). The contact with different Universities, Institutes, Companies as well as directly with the European Commission (trough their scientific officers) as allowed to develop the necessary competences for the identification of new technological opportunities and their viability (see pag.7). EVALUATION AT THE EUROPEAN COMISSION Since 2008 has been selected as Expert Evaluator for the European Commission of proposals in the frame of the 7 th Work Programme and of COST actions (European Cooperation in Science and Technology). Evaluator for the Chemistry panel of the PEOPLE Programme: Marie Curie International Outgoing Fellowships for Career Development (IOF); Intra-European Fellowships for Career Development (IEF); International Incoming Fellowships (IIF). REVIEWER OF INTERNATIONAL JOURNALS: Biotechnology Progress, Biomaterials, Journal of Biomedical Materials Research, Journal of Biomaterials Science- Polymer Edition, Encyclopedia of Biomaterials and Biomedical Engineering, Journal of Clinical Rehabilitative Tissue Engineering Research, Journal of Tissue Engineering and Regenerative Medicine. Lecturing Supervision Experience LECTURING C.A.P - Certificate of pedagogic Aptitude / Qualified Teacher Status Has lectured several tutorials and workshops to master students and students in the first year of their PhD. Has co-supervised several Master and PhD thesis. ORGANIZATION OF SCIENTIFIC EVENTS Has given contributions to: the design of several scientific and social programs; dissemination actions and pressreleases; selection of the accommodation; preparation of budgets; contact with sponsors and local entities; evaluation and selection of participants; preparation of proceedings. All this competences were acquired in a collaborative context which allowed for the development of a strong team work. May 2006 Informatics AWARDS STAR-Student Travel Achievement Recognition awarded by the Society for Biomaterials at the 31ª Conference of the Society for Biomaterials, Pittsburgh EUA, 2006 as an outstanding contribution to the Society For Biomaterials. OTHER QUALIFICATIONS Microsoft Windows Microsoft Office Word, Excel and PowerPoint Origin Adobe Photoshop EndNote English Spanish French LANGUAGE SKILLS Excellent (conversation, reading and writing, practiced in EUA) Excellent (conversation, reading and writing, practiced in Spain) Good (conversation, reading) 2/7

3 PUBLICATIONS LIST International peer reviewed articles 1. Oliveira AL, Pedro AJ, Arroyo CS, Mano JF, Rodriguez G, Roman JS and Reis RL, 2010, Biomimetic Ca-P Coatings Incorporating Bisphosphonates Produced on Starch Based Degradable Biomaterials, Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 92B, Oliveira AL, Sun L, Kim HJ, Hu X, Rice W, Kluge J, Reis RL and Kaplan DL, 2008, Designing silk-based 3D architectures with controlled lamellar morphology, Tissue Engineering Part A, 14 (5) : 718 (outline). 3. Gomes S, Boulon ME, Oliveira AL, Leonor IB, Mano JF and Reis RL, 2008, Mineralization of Chitosan Membrane Using a Double Diffusion System for Bone Related Applications, Advanced Materials Forum, IV : Oliveira AL, Malafaya PB, Costa SA, Sousa RA and Reis RL, 2007, Micro-computed tomography (mu-ct) as a potential tool to assess the effect of dynamic coating routes on the formation of biomimetic apatite layers on 3D-plotted biodegradable polymeric scaffolds, Journal of Materials Science-Materials in Medicine, 18 (2) : Oliveira AL, Costa SA, Sousa RA and Reis RL, Nucleation and Growth of Biomimetic Apatite Layers on 3D- Plotted Biodegradable Polymeric Scaffolds: Effect of Static and Dynamic Coating Conditions, Acta Biomaterialia, 5 (5), (2009), Oliveira AL, Reis RL and Li P, 2007, Strontium-Substituted Apatite Coating Grown on Ti6Al4V substrate through Biomimetic Synthesis, Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 83B : Chin H, Hutmacher DW, Chou AM, Oliveira AL, Reis RL and Lim TC and Schantz J-T, 2006, A comparative analysis of scaffold material modifications for load-bearing applications in bone tissue engineering, International Journal of Oral and Maxillofacial Surgery, 35/10 : Oliveira AL, Mano JF, Roman JS and Reis RL, 2005, Study of the Influence of Beta-Radiation Sterilization on the Properties and Mineralization of Different Starch Based Polymers, Journal of Biomedical Materials Research. Part B: Applied Biomaterials, 74B/1 : Oliveira AL and Reis RL, 2004, Pre-mineralisation of starch/polycrapolactone bone tissue engineering scaffolds by a calcium-silicate-based process, Journal of Materials Science-Materials in Medicine, 15 (4) : Oliveira AL, Mano JF and Reis RL, 2003, Nature-Inspired Calcium Phosphate Coatings: Present Status and Novel Advances in the Science of Mimicry, Opinion on Solid State & Materials Science, 7/4-5 : Sousa RA, Oliveira AL, Reis RL, Cunha AM and Bevis MJ, 2003, Bi-composite sandwich moldings: Processing, mechanical performance and bioactive behavior, Journal of Materials Science-Materials in Medicine, 14 (5) : Oliveira AL, Malafaya PB and Reis RL, 2003, Sodium Silicate Gel as a Percursor for the in vitro nucleation and Grow of a Bone-like Apatite Coating in Compact and Porous Polymeric Structures, Biomaterials, 24/15 : Oliveira AL, Alves CM and Reis RL, 2002, Cell adhesion and proliferation on biomimetic calcium-phosphate coatings produced by a sodium silicate gel methodology, Journal of Materials Science-Materials in Medicine, 13 (12) : Oliveira AL, Elvira C, Reis RL, Vazquez B and San Roman J, 1999, Surface modification tailors the characteristics of biomimetic coatings nucleated on starch-based polymers, Journal of Materials Science- Materials in Medicine, 10 (12) : /7

4 Book Chapters 1. Oliveira AL, Reis RL d Li P, 2007, Biomimetic Synthesis of a Strontium-Substituted Apatite Coating Grown on Ti6Al4V Substrate, In Bioceramics 19Trans. Tec. Publications, Zurich, Oliveira AL, Santos MI, Pedro AJ and Reis RL, 2004, Bisphosphonates Incorporated on a Ca-P Biomimetic Coating Produced by a Sodium Silicate Based Methodology Stimulate Osteoblastic Activity, In Bioceramics 17, eds. Panjian Li, Trans. Tec. Publications, Zurich, Oliveira AL and Reis RL, 2004, Bone-Like Apatite Coatings Nucleated on Biodegradable Polymers as a Way to Induce Bone Mineralization: Current Developments and Future Trends, In Biodegradable Systems in Medical Functions: Design, Processing, Testing and Applications, eds. Rui L. Reis, Julio San Roman, CRC Press, Boca Raton, Gomes ME, Oliveira AL and Reis RL, 2004, Inginiería de Tejidos: Principios Básicos, Suportes y Células Madre, In Biomaterials, eds. R. Sastre, A. de Aza, J. San Roman, Faenza Editrice Iberica S.L,, Leonor IB, Azevedo HS, Pashkuleva I, Oliveira AL, Alves CM and Reis RL, 2004, Learning from Nature How To Design Biomimetic Calcium-Phosphate Coatings, In Learning from Nature How to Design New Implantable Biomaterials: From Biomineralization Fundamentals, eds. Reis R. L. and Weiner S., NATO/ASI Series, Kluwer Press, Drodercht, Leonor IB, Oliveira AL and Reis RL, 2003, Recubrimientos biomimeticos, In Biomateriales, eds. Sastre R., de Aza S. and San Román J., Faenza Editrice, Oliveira AL, Sousa RA, Cunha AM and Reis RL, 2002, Bi-composite sandwich injection moulding: A new method of producing stiff and strongly bioactive bone-analogues, In Bioceramics 14, Oliveira AL, Gomes ME, Malafaya PB and Reis RL, 2002, Biomimetic Coating of Starch Based Polymeric Foams Produced by a Calcium Silicate Based Methodology, In Bioceramics 15, eds. B. Ben-Nissan, D. Sher, W. Walsh, Trans. Tec. Publications, Zurich, Oliveira AL, Leonor IB, Elvira C, Azevedo MC, Pashkuleva I and Reis RL, 2002, Surface Treatments and Precalcification Routes to Enhance Cell Adhesion and Proliferation, In Polymer Based Systems on Tissue Engineering, Replacement and Regeneration, eds. R. L. Reis and D. Cohn, Kluwer Press, Drodercht, Oliveira AL, Leonor IB, Malafaya PB, Alves CM, Azevedo HS and Reis RL, 2002, Tailoring the bioactivity of natural origin based polymers systems: from bone-analogue composites to an all range of biomimetic calciumphosphate coating methodologies, In Bioceramics 15, eds. B Ben-Nissan, D Sher, W Walsh, Trans Tech Pub, Zurich, Oliveira AL, Malafaya PB and Reis RL, 2000, Sodium silicate-gel induced self-mineralization of different compact and porous polymeric structures, In Bioceramics vol. 13, eds. Sandro Giannini and Antonio Moroni, Trans Tec. Publications, Zurich, Oral Communications 1. Oliveira AL, Silk-Based Biomaterials: Processing Windows for Bone Tissue Engineering, 3rd Marie Curie Cutting Edge Practical Training Course on Fabrication and characterisation of tissue engineering scaffolds, University of Minho, Avepark, Guimarães, Portugal 2. Oliveira AL, Sampaio SC, Sousa RA and Reis RL, Nature-Inspired Silk Fibroin/Hydroxyapatite Hybrid Bioactive Scaffolds for Bone Tissue Engineering Applications, 3rd Marie Curie Cutting Edge Conference on Biomineralisation of polymeric materials, bioactive biomaterials and biomimetic methodologies, Funchal (Madeira), Portugal, May Oliveira AL, Costa SA, Sousa RA and Reis RL, Studies on the Formation of Biomimetic Apatite Layers on 3D-Printed Biodegradable Polymeric Scaffolds: Effect of Different Dynamic Coating Routes, 2006 Annual Meeting of the Society from Biomaterials, Pittsburgh, United States of America, May /7

5 4. Oliveira AL, Costa SA, Sousa RA and Reis RL, Static and Dynamic Coating Routes and its Influence on the Kinetics for Biomimetic Apatite Formation on 3D-Plotted Biodegradable Polymeric Scaffolds, 1st Marie Curie Cutting Edge Conference on New developments on polymers for tissue engineering: replacement and regeneration, Funchal (Madeira), Portugal, May Oliveira AL, Sampaio SC, Sousa RA and Reis RL, Controlled Mineralization of Nature-Inspired Silk Fibroin/Hydroxyapatite Hybrid Bioactive Scaffolds for Bone Tissue Engineering Applications, 20th European Conference on Biomaterials, Nantes, France, May Oliveira AL, Sousa RA, Malafaya PB, Costa SA and Reis RL, Micro-CT a Valuable Tool to Study the Effect of Dynamic Coating Routes on the formation of Biomimetic Apatite Layers on 3D-Plotted Biodegradable Polymeric Scaffolds, 20th European Conference on Biomaterials, Nantes, France, May Sampaio SC, Oliveira AL, Sousa RA and Reis RL, Regenerating Silk Fibroin and Precipitating Hydroxyapatite-2 in 1 Methodology, for Creating Silk Fibroin-Hydroxyapatite Hybrid Scaffolds for Bone Tissue Engineering, 20th European Conference on Biomaterials, Nantes, France, May Oliveira AL, Mano JF, Arroyo CS, Rodriguez G and Roman JS, Structure and Stability of Ca-P Biomimetic Coatings Incorporating a Bisphosphonate, Frontiers in Biomedical Polymers, Granada, Spain, May Oliveira AL, Santos MI, Coutinho OP and Reis RL, Biomimetic Coatings Incorporating Bisphosphonates Aiming to Inhibit Bone Resorption, 7th World Biomaterial Congress, Sydney, Australia, May Oliveira AL, Santos MI, Pedro AJ and Reis RL, Bisphosphonates Incorporated on a Ca-P Biomimetic Coating Produced by a Sodium Silicate Based Methodology Stimulate Osteoblastic Activity, Bioceramics 17, New Orleans, United States of America, May Oliveira AL, Alves CM and Reis RL, Biomimetic Routes for Inducing In Vitro Biomineralization on Starch- Based Polymeric Structures for Bone-Related Applications, XVIIth Aachen Colloquium on Biomaterials, Aachen, Germany, May Oliveira AL, Alves CM, Gomes ME, Malafaya PB and Reis RL, Silicate Gels as Precursors of Biomimetic Mineralization on Degradable Polymeric Scaffolds, NATO/ASI- Advanced Study Institute course on Learning from Nature How to Design New Implantable Biomaterials: From Biomineralization Fundamentals to Biomimetic Materials and Processing Routes, Alvor, Portugal, May Oliveira AL, Malafaya PB, Gomes ME and Reis RL, Pre-Mineralization of Starch Based Bone Tissue Engineering Scaffolds by a Calcium Silicate Based Process, 18th European Conference on Biomaterials, Stuttgart, Germany, May Oliveira AL and Reis RL, Strategies for Developing Natural Origin Materials for Biomedical Applications, Workshop on Perspectives in Marine Bioadhesives Engineering: Mimicking Marine Bioadhesives towards Novel Applications, Brussels, Belgium, May Oliveira AL, Leonor IB, Malafaya PB, Alves CM, Azevedo HS and Reis RL, Tailoring the bioactivity of natural origin based polymers systems: from bone-analogue composites to an all range of biomimetic calciumphosphate coating methodologies, Bioceramics 15, Sydney, Australia, May Salgado AJ, Oliveira AL, Coutinho OP and Reis RL, Evaluating Biomimetic Ca-P Coatings for Improvement of Cellular Adhesion to Starch Based Scaffolds, 17th Conference of the European Society for Biomaterials, Barcelona, Spain, September Oliveira AL, Alves CM and Reis RL, Cell Adhesion and Proliferation on Biomimetic Calcium-Phosphate Coatings Produced by a Sodium Silicate Gel Methodology, 17th European Conference on Biomaterials, Barcelona, Spain, May Oliveira AL, Gomes ME, Malafaya PB and Reis RL, Biomimetic coating of starch based polymeric foams produced by a calcium silicate based methodology, Bioceramics 15, Sydney, Australia, May /7

6 19. Oliveira AL and Reis RL, Novel Biomimetic Approaches for The Pre-Calcification of Biodegradable Implants Materials, Society For Biomaterials 27th Annual Meeting, Minnesota, United States of America, May Oliveira AL, Sousa RA and Reis RL, Bi-Composite Sandwich Injection Moulding: a New Method of Producing Stiff and Stronger Bioactive Bone-Analogues, Bioceramics 14, Palm Springs, United States of America, May Oliveira AL and Reis RL, Calcium Silicate Coating as a New Precursor for The Formation of a Bonelike Apatite Layer in Compact and Porous Starch Based Polymeric Structures, 16th European Conference on Biomaterials, London, United Kingdom, May Oliveira AL and Reis RL, Innovative Method for The Pre-calcification of Novel Starch Based Biomaterials, I Congresso Ibérico de Biomateriais e Biosensores - Bioávila, Ávila, Spain, May Oliveira AL, Elvira C, Feng Y, Azevedo MC, Rebouta L, Cunha AM and Reis RL, Surface Modifications of Degradable Starch Based Thermoplastics Aimed at Improving Cell Adhesion and Proliferation, Seminário DEP, Guimarães, Portugal, May Oliveira AL, Malafaya PB and Reis RL, Sodium Silicate Gel Induced Self-Mineralization of Different Compact and Porous Polymeric Structures, Bioceramics 13, Bologna, Italy, May Oliveira AL, Elvira C, Vásquez B, Roman JS and Reis RL, Surface Modifications Tailors the Characteristics of Biomimetic Coatings Nucleated on Starch Based Polymers, 15th European Conference on Biomaterials, Bordeaux, France, May 1999 Poster Communications 1. Oliveira AL, Sun L, Kim HJ, Hu X, Rice W, Kluge J, Reis RL and Kaplan DL, 2008, Designing silk-based 3D architectures with controlled lamellar morphology, Annual Meeting of the Tissue Engineering and Regenerative Medicine International Society (TERMIS), Porto, Portugal, June Leonor IB, Oliveira AL, Alves CM, Pereira RC, Azevedo HS and Reis RL, Biomimetic Strategies For Bone Tissue Engineering, EXPERTISSUES Workshop on Cells-Biomaterials Interactions, Prague, Czech Republic, October Oliveira AL, Malafaya PB, Sousa RA and Reis RL, Development of bone tissue engineering scaffolds through integration of melt based rapid prototyping and dynamic biomimetic coating routes, 2nd Marie Curie Cutting Edge InVENTS Conference on Recent advances on polymeric based systems for controlled delivery of bioactive agents: Applications in Tissue Engineering, Funchal, Portugal, June Oliveira AL, Pedro AJ, Arroyo CS, Mano JF, Rodriguez G, Roman JS and Reis RL, Biomimetic Ca-P Coatings Incorporating Bisphosphonates Produced on Starch Based Degradable Biomaterials, 19th European Conference on Biomaterials, Sorrento, Italy, May Oliveira AL and Reis RL, Biomimetic Strategies for the Pre-Mineralization of Porous Biodegradable Polymeric Scaffolds with a Bone-Like Apatite Layer, 12th Annual POLYCHAR World Forum on Advanced Materials, Guimarães, Portugal, May Salgado AJ, Oliveira AL, Figueiredo JE, Coutinho OP and Reis RL, Biological Response to 3D Pre- Mineralized Scaffolds for Bone Tissue Engineering: Cytotoxicity, Cell Culture and Protein Expression, 29th Annual Meeting of the Society for Biomaterials, Reno, United States of America, April Oliveira AL, Malafaya PB, Gomes ME and Reis RL, Biomimetic Strategies for Producing Calcium-Phosphate Coatings on Porous Biodegradable Polymeric Scaffolds, 28th Annual Meeting of the Society from Biomaterials, Tampa, United States of America, May Oliveira AL, Malafaya PB and Reis RL, Distinct Approaches to Produce Bone-Like Biomimetic Coatings on Compact and Porous Biodegradable Polymeric Biomaterials, NATO/ASI- Advanced Study Institute course on Polymer Based Systems on Tissue Engineering, Replacements and Regeneration, Alvor, Portugal, May /7

7 9. Oliveira AL, Mano JF, Roman JS and Reis RL, Study of The Effect of b-radiation Sterilization on The Properties of Different Starch Based Polymers, 16th European Conference on Biomaterials, London, United Kingdom, May Oliveira AL and Reis RL, Pre-Calcification Processing Routes to Produce Bone-Like Coatings on Different Biodegradable and Inert Polymeric Biomaterials, European Physics Society EPS2000, Guimarães, Portugal, May Oliveira AL and Reis RL, Controlling the Biomineralization of Natural Origin Polymeric Biomaterials, Gordon Research Conference on Biomineralization, New Hampshire, New Hampshire, United States of America, May Oliveira AL, Leonor IB and Reis RL, Biomimetic Approaches for The Pre-Calcification of Polymeric Biomaterial Surfaces and Porous Architectures, Gordon Research Conference on Biomineralization, New Hampshire, United States of America, May Oliveira AL, Roman JS and Reis RL, Surface Modifications of Starch Based Polymers as a Tool for Controlling the In-vitro Nucleation and Grow of a Bone-like Calcium-phosphate Coating, International Conference on Biopolymer Technology, Coimbra, Portugal, May Oliveira AL and Reis RL, Effect of Surface Modification on the In-vitro Mineralization of a Starch Based Polymer for Bone Replacement, Gordon Research Conference on Biomineralization, New Hampshire, United States of America, May 1998 PARTICIPATION IN PROJECTS Has given contributions in the following international projects "ISOBONE- A Tissue Engineered Living Bone Equivalent, Project BRITE/EURAM III, partners - IsoTis bv (NL), U. Minho (PT), U. Twente (NL), Novamont (IT), Cinpres (UK), Brunel Univ. (UK), and INEB (PT), Jun May 2002, total budget of around 6.4 MEuros (budget of U. Minho, Euros) (Finished 2002). ALGISORB Algae Origin Bone Stimulators Enriched with Growth Factors, Project CRAFT, Leaded by the company CMF (Vienna, Austria), in collaboration with 6 companies and 3 European Universities. Budget UM Euros (Finished 2003). Coordination by U. Minho. "HIPPOCRATES - A Hybrid Approach and Cartilage Tissue Engineering using Natural Origin Scaffolds, Progenitor Cells and Growth Factors", STREP Project, (this Project involves more 3 Universities from Germany, Austria and North Ireland, Red Cross from Austria and 2 top European companies Germany and Belgium), total budget: 2.9 MEuros (UM Euros). Started: January Coordination by U. Minho. EXPERTISSUES Network of Excellence (NoE) on Novel Therapeutic Strategies for Tissue Engineering of Bone and Cartilage Using Second Generation Biomimetic Scaffolds, Coordinator: Rui L. Reis (U. Minho), 20 partners of 13 countries; being 3 Industrial partners.the total budget for this project is about 7.3 MEuros (for the UM the expected budget is about Euros). Contributed to the authorship and/or management of the following projects Is the Principal Investigator of the project TISSUE2TISSUE - Using Textile Technologies to Develop Innovative 3D Architectures to Be Applied in Bone Tissue Engineering, in the University of Minho, approved for funding by FCT (Portuguese Foundation for Science and Technology) in 2010 (duration: 3 years), Budget Euros. DEPUY Novel Biomimetic Coating Methodologies, research contract with Depuy Orthopaedics (Jonhson & Jonhson), Warsaw, Indiana, USA, funding US$. "ALEA JACT EST - Shaping the Future of a New Generation of Hybrid Human Resources for the Tissue Engineering of Connective Tissues", Marie Currie Early Stage Training (EST) Network, Rui L. Reis - Project Coordinator (this project involves 5 other international partners), total budget 2.6MEuros (3B's Euros). BIOLEARN Learning From Nature How to Design Biomimetic Routes for Producing Calcium-Phosphate Coatings on Polymeric Biomaterials, funded by FCT in 2003 (duration: 3 years), Rui L. Reis Principal Investigator, Funding Euros. 7/7