ESOMAR 28 Questions. 1. What experience does your company have in providing online samples for market research?

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1 ESOMAR 28 Questions COMPANY PROFILE 1. What experience does your company have in providing online samples for market research? Since 1996, DoctorDirectory has specialized in deploying healthcare market research to physicans and other healthcare practitioners to serve the needs of market research clients that require measurable results. Our fully opted-in prescribers enjoy the benefits of membership in the DoctorDirectory community. In addition to Market Research opportunities, we offer an online sample program including many pharma brands, a resource center and more all from the convenience of their personal homepage in the DoctorDirectory HCP site. This relationship allows us to fill studies with large quotas and low incidence rates that may be a challenge for other providers. SAMPLE SOURCE 2. Please describe and explain the type(s) of online sample sources from which you get respondents. Are these databases? Actively managed research panels? Direct marketing lists? Social networks? Web intercept (also known as river) samples? The DoctorDirectory sample for conducting online research is drawn from our proprietary directory of more than 700,000 licensed, practicing prescribers in the US. From that directory we can access over 670,000 health care professionals electronically.

2 3. If you provide samples from more than one source: How are the different sample sources blended together to ensure validity? How can this be replicated over time to provide reliability? How do you deal with the possibility of duplication of respondents across sources? DoctorDirectory does not provide samples from multiple sources. 4. Are your sample source(s) used solely for market research? If not, what other purposes are they used for? In addition to Market Research opportunities, we offer an online sample program including many pharma brands, a resource center, and more all from the convenience of their personal homepage in the DoctorDirectory HCP site. Physicians are also contacted with information about products and medical education bulletins. 5. How do you source groups that may be hard to reach on the internet? For physician market research, DoctorDirectory accesses its physicians and other healthcare professionals through a variety of channels, including DoctorDirectory s website, , phone, fax, and US postal mail, thereby limiting reliance on internet reach. DoctorDirectory s database includes a variety of profiling data that can be used to specifically target groups. 6. If, on a particular project, you need to supplement your sample(s) with sample(s) from other providers, how do you select those partners? Is it your policy to notify a client in advance when using a third party provider? DoctorDirectory does not have the need to supplement physician samples with samples from other providers. In the rare instance where calculations indicate a need for additional HCPs, DoctorDirectory recruits from established HCP specialty association lists. DoctorDirectory ensures the quality of the sample populations with its internal, multi-step deduplication process that is completed prior to recruitment. DoctorDirectory does inform the client of these efforts prior to engagement. SAMPLING AND PROJECT MANAGEMENT 7. What steps do you take to achieve a representative sample of the target population? Sample invitations are based upon the specifications of each market research study and project timing. Once a target group has been defined and pulled, invitations are released to the entire group or a subset of the group. For a subset, invitations are randomly pulled until the study has been filled or the larger group has been exhausted.

3 8. Do you employ a survey router? DoctorDirectory does not employ a survey router. Since questions 9 11 pertain to a survey router, we ll move on to question 12 next. 12. What profiling data is held on respondents? How is it done? How does this differ across sample sources? How is it kept up-to-date? If no relevant profiling data is held, how are low incidence projects dealt with? Upon registration, DoctorDirectory s members are required to enter their academic holding, medical specialty, state license, DEA number, contact information, and address. Information such as address, region, gender, and education can be used to meet the client s targeting needs. Additional profiling data can be obtained via screener, if required. DoctorDirectory s Physician Relations Department maintains on-going verification and scrubbing of the membership directory. 13. Please describe your survey invitation process. What is the proposition that people are offered to take part in individual surveys? What information about the project itself is given in the process? Apart from direct invitations to specific surveys (or to a router), what other means of invitation to surveys are respondents exposed to? You should note that not all invitations to participate take the form of s. A typical invitation includes the survey topic, the length and the honorarium offered. The invitation has a unique link into the survey. Although in some cases respondents are directed to a third party hosting site, the unique link passes them first through a DoctorDirectory survey gateway page, which allows respondents to confirm their identity. These invitations are distributed via , fax, and postal mail and are included on the member s personal DoctorDirectory homepage.

4 14. Please describe the incentives that respondents are offered for taking part in your surveys. How does this differ by sample source, by interview length, by respondent characteristics? We offer respondents who complete the survey an honorarium paid by company check. That honorarium payment amount fluctuates based on specialty, length of survey, size of sample relative to size of the universe of physicians, incidence rate and other variables. Survey respondents who complete a survey are paid by company check. We are in the process of testing alternative methods of honorarium such as gift cards. 15. What information about a project do you need in order to give an accurate estimate of feasibility using your own resources? Length of survey, incidence rate, quota groups, overall quota, and fielding time. 16. Do you measure respondent satisfaction? Is this information made available to clients? At the completion of a survey, a respondent has the opportunity to provide feedback. We also maintain a Physician Relations Department that is accessible to respondents by phone or via . A physician can also provide feedback through their personal homepage on the DoctorDirectory.com website. It is not the common practice to share respondent satisfaction with clients. On the occasion when respondent satisfaction impacts the survey participation, DoctorDirectory will communicate specific measurements, such as rate of qualification, tech issues, and negative experiences, available to the client as needed. 17. What information do you provide to debrief your client after the project has finished? At the completion of each project, the project team participates in a debrief session with the client to provide performance metrics and any additional information that the client has requested a specific project.

5 DATA QUALITY AND VALIDATION 18. Who is responsible for data quality checks? If it is you, do you have in place procedures to reduce or eliminate undesired within survey behaviours, such as (a) random responding, (b) Illogical or inconsistent responding, (c) overuse of item non-response (e.g. Don t Know ) or (d) speeding (too rapid survey completion)? Please describe these procedures. A formal quality management system, along with it SOPs, governs all programs executed by DoctorDirectory. DoctorDirectory reviews all surveys prior to fielding, no matter who hosts the survey, to determine accuracy of content, length of survey and honoraria for the intended audience. We review the screener to ensure terminating points are at the beginning and that physicians are terminated at the point of termination. We check for special instructions i.e. sound, Flash, particular browsers. We verify quotas are set up correctly as contracted. Project Managers verify the client has redirects set up correctly and physicians are passed back to DoctorDirectory correctly for termination, quota full and completion. The Project Manager then checks the DoctorDirectory system to make sure all data was captured correctly. 19. How often can the same individual be contacted to take part in a survey within a specified period whether they respond to the contact or not? How does this vary across your sample sources? DoctorDirectory can apply participation criteria/business rules to any of its participants based on the needs of a client for a specific project. Records are kept on every study and every respondent for all programs conducted through DoctorDirectory. Because DoctorDirectory does not have visibility into the total number of third party survey programs in which a physician has enrolled, DD does not generally limit the frequency of communication unless dictated by business rules. 20. How often can the same individual take part in a survey within a specified period? How does this vary across your sample sources? How do you manage this within categories and/or time periods? The ability to limit participation is based upon the individual client requirements. Invitations are randomly rotated unless the sample universe is limited. Every physician in the DoctorDirectory community is assigned his/her own identification number which allows us to track participation history. This information is available; however the disclosure of individual-level data is provided only in cases where it is compliant with privacy policy and regulations.

6 21. Do you maintain individual level data such as recent participation history, date of entry, source, etc., on your survey respondents? Are you able to supply your client with a project analysis of such individual level data? Every physician in the DoctorDirectory community is assigned his/her own identification number which allows us to track participation history. This information is available; however the disclosure of individual-level data is provided only in cases where it is compliant with privacy policy and regulations. 22. Do you have a confirmation of respondent identity procedure? Do you have procedures to detect fraudulent respondents? Please describe these procedures as they are implemented at sample source registration and/or at the point of entry to a survey or router. If you offer B2B samples what are the procedures there, if any? DoctorDirectory employs a rigorous, ongoing verification process. This process occurs using state licensing and DEA/NPI numbers and checked quarterly with each DEA/NPI update. A physician is thoroughly verified prior to being added to the directory. POLICIES AND COMPLIANCE 23. Please describe the opt-in for market research processes for all your online sample sources. Physicians opt in to the DoctorDirectory community and the various services, including , either by a) registration on the website or b) through a special screen prior to participations in a survey or sample opportunity.

7 24. Please provide a link to your Privacy Policy. How is your Privacy Policy provided to your respondents? Please click on the link below to be taken to DoctorDirectory s Privacy Policy: Privacy Policy accessible from all pages of the HCP website Designated contact within organization to serve as internal point of contract for data privacy issues. Designated contact within organization to serve as external point of contact for data privacy issues. Automated Opt-Out in all s Internal Do-Not-Contact List 25. Please describe the measures you take to ensure data protection and data security. DoctorDirectory operates a secure data network protected by industry standard firewall, virus scanning and prevention, and password protection systems. Only authorized personnel have access to our information. A security and privacy policy is periodically reviewed and updated as necessary. 26. What practices do you follow to decide whether online research should be used to present commercially sensitive client data or materials to survey respondents? Information and content within a survey is the responsibility of the client and programming providers. 27. Are you certified to any specific quality system? If so, which one(s)? DoctorDirectory follows documented quality assurance processes for content, design and formatting, grammar and spelling, programming, and timing. Sign-off on each process is required through an electronic system in which each department involved in the project must verify the quality.

8 28. Do you conduct online surveys with children and young people? If so, do you adhere to the standards that ESOMAR provides? What other rules or standards, for example COPPA in the United States, do you comply with? Minors (under age 21) are not invited to participate. DoctorDirectory conducts surveys only among verified US physicians and other health professionals. DoctorDirectory is compliant with all United States laws and adheres to the CASRO standard.

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