How To Use A Cypress Diagnostics System

Transcription

1 English Catalogue

2 Contents 2 Biochemistry 4 Biochemistry Analysers 4 CYANStart: Semi-Automatic Biochemistry Analyser 6 CYANPro: Automatic Biochemistry Analyser 10 CYANExpert 130: Random Access Biochemistry Analyser 15 Biochemistry Reagents 16 Electrolytes 18 Enzymes 18 Lipids 20 Substrates 21 Control Sera 21 Calibrators 29 Stains 29 Bacteriology Stains 29 Hematology Stains 29 Histopathology Stains - Papanicolaou 29 Ancillary Products 30 Blood Grouping Reagents 30 ABO grouping 31 Subtypes 32 Agglutination/Latex Kits 33 Rapid Tests 33 General 34 Pregnancy Rapid Tests 34 Parasitic 21 Turbidimetry 22 Hematology 22 CYANHemato: Automatic Hematology Analyser 24 Reagents 24 Cleaners 24 Controls 25 Coagulation 25 CYANCoag: Semi-Automatic Coagulation Analyser 26 Reagents 26 Controls 27 Microbiology 27 Antibiotic discs 28 Culture media 35 Bacterial Antigens 36 Strips 36 CYANStrip: Strip Reader 37 Strips 38 Strips for Diabetes Follow-up 39 Drugs of Abuse 39 Elisa 39 Parasitic Line 40 CYDIS Disinfectants 40 CYDIS Derm 40 CYDIS Surface 40 CYDIS Extra

3 Notes: Dear, Cypress Diagnostics is a supplier for small and medium sized clinical laboratories. We are a quality oriented and ISO certified company with CE approved products. Our production facility is located in Langdorp, Belgium. Our products are preferred and appreciated in more than 100 countries worldwide. Cypress Diagnostics has a dynamic product range defined by the customers needs and wants. Our diagnostic kits are sold under the Cypress Diagnostics brand name. The CYAN product range covers laboratory equipment and consumables. Together they provide an integrated platform. This integrated platform enables us to offer a superior solution to our customers, by providing benefits of the quality guarantee together with the elimination of costs. This results in an increased productivity and efficiency. Please feel free to contact your local distributor for more information. Test the difference The Cypress Diagnostics Team Legend: CA: card Col: Colorimetric CS: Cytological samples CSF: Cerebral Spinal Fluid Ep: End-Point FA: Faeces Kin: Kinetic L: slide Liq : liquid Ly: lyophilised MTP: Microtitre Plate NA: Not Applicable ON: On request only PL: Plasma PS: Pathological Samples R + C: reagent + control R + S: reagent + standard R: reagent RC: Red Blood Cells SE: Serum ST: dipstrip UR: UV: Ultra-violet V/F: vial dropper WB: Whole Blood

4 Good to know Biochemistry How to deliver high standards of laboratory services with limited resources? The Cypress Diagnostics platform of biochemistry reagents and analysers is our answer to this question. All our customers face the constant pressure to lower operating costs while adhering to the best diagnostics practices. Our solutions can solve your challenges too. Please feel free to contact one of our trained distributors for more information. Quick delivery Why choose for the Cypress Diagnostics biochemistry platform? Ease of use: Intuitive operations ensure effortless testing and enhanced productivity Quick to learn procedures, save time and costs Dynamic and real-time display of analyser running status, creates situation awareness and helps to multi-task Growing line of liquid-stable reagents simplify user operations Pre-programmed settings eliminate the need to input test parameters Different language options are available Certified products Great to use Made in Europe Trained distributors Customer focused High accuracy testing: Precise results every time Reliable results avoid confirmatory testing and save costs Automatic flagging provides comprehensive visual highlights Highly sensitive photometer Low drift photometers for consistent measurements hour after hour Calibrators and controls available Wide test menu: Availability of liquid ready to use and lyophilized reagents Reagents available in small and larger pack size Expanding range of turbidimetric kits Complete assortment of assays for a well informed and accurate diagnosis Test menu includes routine chemistry, lipids, diabetes, electrolytes, cardiac, renal and liver functions Liquid enzymatic Sodium and Potassium kits under development Full set of calibrators & controls available Proven methodologies and industry standards Ongoing commitment to develop new methods and enhancements 1 2

5 Cost savings: Low reagent consumption Low maintenance requirements Reagents have extended stability Analysers with robust design for reduced complexity and increased reliability Reduced sample volume: Test a wide range of analytes from as little as 2 to 5 µl of sample Small sample volume allows multiple tests to be performed from a single sample, ideal for pediatric testing Versatility: Space saving compact design of analysers Analysers give real time activity & result status to track your turn around time (TAT) target All analysers cover 110 & 220 Volt at 50 & 60 Hz We provide application sheets for the validated use of our reagents on other analysers Intuitive operations: Innovative reagents require less handling Require minimal training, saving time and costs Growing library of illustrated aids available The analysers provide clear step by step instructions for each use Support: Our distributors receive regular trainings to ensure that they can provide adequate technical support for reagents and analysers The CYANPro and CYANExpert 130 are only distributed by trained distributors Biochemistry Analysers CYANStart: Semi-Automatic Biochemistry Analyser Why CYANStart? Cost savings: Minimum reaction volume of 500 µl results in a decreased cost per test No consumables required Extra consumables included at delivery (two fuses, five paper rolls and one spare lamp) Long life lamp Robustness of the analyser, guides the user and reduces mistakes Flexibility: On board printer for automatic or on request printing Seven wavelengths (340, 405, 492, 510, 546, 578 & 620 nm filters) cover all clinical diagnostics applications Five calculation methods (absorbance, endpoint, two-point, kinetic, bichromatic) and three calibration methods (factor, calibrator & multi-point calibration) provide plenty processing options with one system Three blank options (sample blank, reagent blank & water) provide background correction of the reagent and sample coloration Convenience: All Cypress Diagnostics biochemistry reagents are pre-programmed at delivery 200 open channels are user programmable to allow for unrestricted testing Large font size, pleases the eye and reduces the effort Large keyboard buttons, for unambiguous manipulation with gloves Minimal daily maintenance Up to 60 tests/hour Aff ordable for every laboratory!!! Now with updated 2013 software! 3 4

6 Technical Specifications General: Data storage: 200 test parameters & 1000 test results Flow cell: 32 μl, 10 mm light path Halogen lamp: 6V/10W Measurement range: 0,000 2,500 ABS Quality control feature Required volume: 500 µl Screen size: 240 x 128 pixels Voltage: 110/230V - 50/60 Hz Languages: English, French, Spanish Printer: Built-in printer Prints graphs 24 characters per line CYANPro: Automatic Biochemistry Analyser Up to 200 tests/hour Temperature control: Peltier element 25 C, 30 C, 37 C, Ambient temperature Weight and dimensions: 8,5 kg 35 x 40 x 24 cm (L x W x H) Order code: CY004: CYANStart Did you know that you can lower your coagulation reagent consumption by 50% with our CYANCoag (CY003)? Enjoy lower operating costs with our coagulation line. Contact our distributor for more information. The CYANPro is an automatic analyser made for expanding, quality focused laboratories. It is the ideal first step into laboratory automatisation. Its powerful software will bring almost unlimited capabilities to your lab. Why CYANPro? Cost savings: Minimum reaction volume of 450 µl results in lower costs per test Long life lamp Among the lowest water consumption in the market True walk away automation optimizes the staff time Lowest service requirements in its class No maintenance, high precision pipetting diluter used Robustness based on proven batch and flowcell system Flexibility: Up to 40 samples Seven wavelengths (340, 405, 492, 510, 546, 576 & 620 nm filters) cover all clinical diagnostics kits Six calculation methods (absorbance, endpoint, two-point, kinetic, bichromatic & differential) and nine calibration methods (factor, calibrator & multi-point calibrations) provide plenty processing options with one system Three blank methods (sample blank, reagent blank & water) provide background correction of the reagent and sample coloration Automated dilution of sample and calibrator simplify operations 5 6

7 Washing well Sampling arm Reagents Samples Aspiration arm Calibrators & controls Reaction cells Software Compared to the competition, the CYANPro software is more powerful and user friendly. Our most stringent users will confirm this. The database can store and retrieve results from other analysers and tests too. It therefore works as a true data hub for your laboratory. The patient database also enables a quick search of results and produces a full lab report making your operations more convenient, reliable and efficient. Data management: Sample based identification with full patient demographics enables to make detailed patient printouts LIS connectivity enables to push and pull data into the system through ASTM standard The large computer based database enables to store unlimited number of results Access codes safeguard the system operation by authorized users only Test counter for convenient reporting to financial department Software Features: Unlimited work list Quality control Sample & calibrator dilution Normal Values are user definable Sample entry for serum/urine Visualization and print-out of graphs Levey Jennings graphs for QC data Methods, calibrator and controls database Historical patient and calibration database Multipoint calibration curves (automated dilution of master calibrator) and corresponding graphs Bidirectional Interface with Host Computer & LIS Communication: USB 1.1/2.0 Full Speed & RS-232 Operative System: Windows XP, Vista & Windows 7 Quality Control: Automatic generation of Levey-Jennings charts, running mean values and QC statistics Built-in flags indicate system checks and abnormalities Convenience: Minimal daily maintenance reduces the workload Password protected accounts enable to work with different users, each having their defined tasks and authorities Removable reagent tray enables an overnight storage in the refrigerator under validated temperatures Software with auto-diagnostic program Built-in flags highlight results All Cypress Diagnostics biochemistry reagents are pre-programmed at delivery Real time feedback: Count down timer to completion Clear real-time visual information of running status 7 8

8 Technical Specifications Operation: Up to 200 colorimetric tests/hr Runs clinical chemistry & turbidimetric tests Batch system Large choice of Cypress Diagnostics reagents available More than 300 clinical applications programmable Measurement procedures: Initial, endpoint, differential, kinetic, bichromatic Blank: water, reagent blank or sample blank Calibration: factor, calibrator and multipoint Samples can be loaded by single test or profile Programmed for 7 different calculation algorithms for linear and non-linear multicalibrator analysis Photometer particulars: Multi wavelength photometer with narrow band interference filters Filters (7): 340, 405, 492, 510, 546, 578, 620 nm Halogen lamp 6V/10 W (2000 hours) Linear range: 0,000 2,500 ABS Resolution: 0,001 ABS Drift: < 0,003 ABS/hour Detector: Silicon photodiode Flow cell: 10 mm light path 37 C temperature controlled (Peltier effect) 50 µl internal volume Carry Over: 2 % nominal for total volume of μl of solution Body: stainless steel & quartz Teflon inlet tube Programmable wash cycle in between tests to avoid cross-contamination Capacity: 40 samples (4 segments with 10 sample cups of 0,8 ml) 1 removable reagent tray (18 reagent containers of 25 ml each) 1 segment for 6 Calibrators and 2 Controls Reaction cuvettes: 114 disposable reaction cells (6 segments of 19 cells) Temperature controlled at 37 C Sampling: High precision diluter module Sample aspiration: 3-99 µl with 1 µl increments Reagent dispensing: µl with 1 µl increments Maximum reaction volume: 1000 µl Minimum reaction volume: 450 µl Precision: CV < 1 % at 3 μl Programmable wash cycle in between tests to avoid cross-contamination Operating environment: In covered and dry places Temperature: 18 C - 32 C Relative humidity: 20 % - 85 % Stable surface (no vibrations) >10 cm around the instrument to permit air circulation Weight & dimensions: 32 x 45 x 50 cm (HxWxL) 22 Kg Power: 110/240 V - 47/63 Hz 180 W Advised: Electronic Stabilizer (> 1kW Power potential) No-Break Module (UPS - Uninterrupted Power Supply) Order code: CY005: CYANPro CYANExpert 130: Random Access Biochemistry Analyser Up to 130 tests/hour The CYANExpert 130 is a continuous loading, random access automatic biochemistry analyser. It is our fastest, most convenient, precise and flexible analyser so far. It includes numerous cost saving features and provides a lot of flexibility to the operator. The software offers advanced data management and QC features. It executes constant checks to increase the validity of the delivered results and to provide real walk away time. During operations, real time visual feedback is provided to the operator. The CYANExpert 130 will reduce the workload and increase the efficiency of your lab. The CYANExpert 130 is intended for expanding, quality focused laboratories, performing up to 800 biochemical and immunoturbidimetric measurements per day. Why CYANExpert 130? Cost savings: Minimum reaction volume of 220 µl results in a decreased cost per test Fluid level detection eliminates testing errors due to empty water, washing solution, controls, calibrators, sample or reagents containers Washing station automatically washes the reaction cuvettes Separate waste lines reduce hazardous waste True walk away automation optimizes the staff time Auto sample re-run eliminates risk of human error Low service requirements Standby lamp status, reduces the power consumption and extends the lifespan of the lamp No maintenance, high precision pipetting diluter used Two sizes of reagent container reduce the dead-volumes 9 10 Data management: Sample and patient based identification enable quick queries and follow-up statistics Sample and reagent barcode identification available in option LIS connectivity enables to push and pull data into the system through ASTM standard Access codes safeguard the system operation by authorized users only Flexibility:

9 Up to 32 samples can be loaded continuously Shorter turn around time (TAT) enables a patient-focused service Priority for STAT tests Universal sample carrousel loads the most common types of primary tubes Eight wavelengths (340, 380, 405, 492, 510, 546, 576 & 620 nm filters) cover all clinical diagnostics kits Five calculation methods (absorbance, endpoint, two-point, kinetic, bichromatic) and nine calibration methods (factor, calibrator, point to point & multi-point calibration) provide plenty processing options with one system Three blank options (sample blank, reagent blank & water) provide background correction of the reagent and sample coloration Pre-heated sampling line reduces incubation and TAT time Quality Control: Automatic generation of Levey Jennings charts, running mean values and QC statistics Automated QC interpretation and control by analyser reduces the workload Double beam optical system increases the measurement precision Cuvettes are QC controlled after washing Convenience: Onboard sample and calibrator dilution available Analyser auto-diagnostics provides accurate system information No daily maintenance Automatic standby function reduces the running costs Password protected accounts enable to work with different users, each having their defined tasks and authorities Automatic system check reduces operator workload Removable reagent tray enables an overnight storage in the refrigerator under validated temperatures All washed cuvettes are automatically tested with blanc levels Real time feedback: Count down timer to completion Clear visual information Real-time display of running status Real-time monitoring of reagent residual volume Real-time diagnosis of system working status Software The CYANExpert 130 is our fastest biochemistry automate. With 130 tests per hour in random access it offers a lot of flexibility. It is an effective and reliable analyzer with first class software. In our vision, the software is the vital element of the CYANExpert 130. We integrated all our knowledge in the programming. Our goal was to hide all the technical sophistication in the background so that the users can benefit from an easy and intuitive operation. In the daily use, the operators of the CYANExpert 130 will not realize how many operations like quality control, instrument and results checks, interconnectivity and others are performed simultaneously in the background. The following examples highlight the sophistication of the software of the CYANExpert 130: The CYANExpert 130 checks on a test per test basis if there is sufficient volume of reagent, washing solution and sample available to perform the test. If insuficient volumes are detected, the analyser will proceed with the remaining workload. A warning informs the operator about this. This safeguard enables the operator to handle other tasks while the analyzer is working. This safeguard results in increased productivity of the laboratory staff (multitasking becomes possible), reduced costs (as no analysis will be invalid due to lacking washing solution, reagents, samples, ) and a higher reliability of the results (tests performed without sufficient reagents are excluded) With the bar code reader and connected LIS (Laboratory Information System) and HIS (Hospital Information System) the CYANExpert s results can be delivered to all medical units in the medical facility. The medical team can get their requested information much quicker. Additionally the system also has a test counter for easy reporting of the activities to the accounting department. The convenience of the data transmission reduces the workload and enables the laboratory to focus on their clinical tasks while reducing administrative tasks. The reporting is straightforward with the database management software. The users can look up the results by sample ID and patient ID. This option simplifies the reporting of historical patient results. The lab can forward all the patient s recorded results in a few seconds. This way, the patient s evolution becomes clearly visible to the doctors and contributes to better therapeutic choices. The CYANExpert 130 is an intelligent system that performs self-checks. It detects, defines and indicates its own errors. The technical service can therefore intervene quicker and arrive with the required spare parts. These functionalities reduce the downtime and increases laboratory productivity The instrument performs the sample re-runs and dilutions automatically according to the operator s programming. These options enable the laboratory to better validate the results while reducing the workload. Washing solutions with level sensor 11 12

10 Technical Specifications Washing station Optional barcode reader Dillution cups Measurements procedures: Endpoint, Fixed Time, Kinetic, Bichromatic Blank: Water, Reagent blank or Sample blank Calibration: Factor, Calibrator and Multipoint Up to three different reagent additions possible for each method Samples can be loaded by single test or profile Programmed for 9 different calculation algorithms for linear and non-linear multipoint analysis 24 reagent containers (35 ml or 6 ml) 12 positions for controls and calibrators Operating environment: In covered and dry places Temperature: 18 C 32 C Relative humidity: 20 %-85 % Stable surface (no vibrations) > 10 cm around the instrument to permit air circulation Pre-heated sampling line Calibrators and controls Samples: 3 ml cups Samples: primary tubes Operation: Random access 130 tests/hr Runs clinical chemistry and turbidimetric tests Large choice of Cypress Diagnostics reagents available Up to 300 clinical applications programmable Photometer particulars: Multi wavelength double beam photometer with narrow band interference filters Filters (8): 340, 380, 405, 492, 510, 546, 576, 620 nm Halogen lamp 6V/10W (2000 hours) Linear range: 0,0005 3,5000 ABS Resolution: 0,0005 ABS Drift: < 0,0001 ABS Detector: Silicon Diode Automatic autozeroing on the sample and reference channel (double beam) Option: Barcode reader for reagents and samples Sampling: High precision diluter module Sample aspiration: 2-99 µl with 1 µl increments Reagent 1 volume: µl with 1 µl increments Reagent 2 & 3 volumes: µl with 1 µl increments Minimum reaction volume: 220 µl Maximum reaction volume: 550 µl Precision: CV < 1% at 2 µl Liquid level sensor Preheated sampling line at 37 C Automatic probe wash cycle in between tests to avoid cross-contamination Cuvettes: 120 semi-disposable reading cuvettes (6 racks with 20 Reagent containers positions) with a 6 mm light path Automatic washing and drying cycle by the washing Semi-disposable reading cuvettes station for reusing the cuvettes Automatic QC of cuvettes after washing Temperature controlled at 37 C Capacity: 32 sample positions (4 racks with 8 positions) of 3 ml sample cups or primary tubes Weight & dimensions: 53 x 57 x 75 cm (H x W x L) 43 Kg Power: 110/240 V 47/63 Hz 300 W Advised: Electronic Stabilizer (> 1kW Power potential) No-Break Module (UPS - Uninterrupted Power Supply) Software features: Unlimited work list Historical patient results database Methods, calibrators and controls database Method programming includes control parameters STAT-samples Quality Control and visualization and printout of graphs (Levey-Jennings) Sample pre-dilution and automatic dilution in rerun mode Automatic rerun programmable Reference values are user definable for serum and urine for child, female and male Sample entry for serum/urine Multipoint calibration curve (automatic dilution of master standard) and relative graphs Bidirectional Interface with Host Computer Auto-Diagnostics Program for a system built on different modules Communication: USB 1.1/2.0 Full Speed & RS-232 Operative System: Windows XP, Vista & Windows 7 Language: English, French and other languages upon request Screen Resolution: 800 x 600 Pixels Order code: CY008 CYANExpert 130

11 Biochemistry Reagents The choice between liquid or lyophilized enzymatic reagents is related to personal preferences and laboratory working conditions. For this reason, Cypress Diagnostics offers reagents of both types with similar quality, precision and linearity. LIQUID enzymatic reagents are ready to use. They therefore don t require any pretreatment such as reconstitution of tablets or powder. These ready to use kits have the following benefits: Time saving - can be used directly after opening Exclusion of manual errors limited handling required Economical - No working reagent lost because of expired stability period This last benefit is one of the most important ones. You avoid losses of working reagent as you have the flexibility to prepare the volume you require for your workload. This is in contrast to lyophilized kits, where you are bound to the packing volumes. For small laboratories, the packing volumes do not always fit the consumption rate. Not only small laboratories, but also laboratories working with fully automated biochemistry analysers enjoy the liquid reagents benefits. Liquid and Lyophilized and Enzymatic Reagents Small and Big Pack Sizes LYOPHILIZED enzymatic reagents also have their advantages. Compared to liquid reagents, they offer superior temperature stability. Laboratories where continuous storage at the indicated temperature is a challenge should opt for the lyophilized enzymatic reagents All our kits are suited for automatic and semi-automatic biochemistry analysers. Applications sheets are available, please contact your distributor for more details. Electrolytes Measurement Samples Number of tests per kit Code Name Method Format Packing Standard included Colorimetric Ultra-violet End-Point Kinetic Serum Plasma Whole Blood CSF T CE CYANStart CYANPro CYANExpert 130 HB0030 Calcium Arsenazo III Liquid 2 x 125 ml 2-8 C CE HB0040 Calcium O-Cresolphtalein Liquid 2 x 125 ml 2-8 C CE HB005 Chloride Thiocyanate Liquid 2 x 125 ml 2-8 C CE HB012 Iron Ferrozine Lyophilised 4 x 50 ml 2-8 C CE HB0130 Magnesium Calmagite Liquid 2 x 125 ml 2-8 C CE HB014 Phosphorus Phosphomolybdate method Liquid 2 x 125 ml 2-8 C CE HB015 Potassium NaTPB - Prec. Liquid 2 x 50 ml 2-8 C CE NA HB016 Sodium Mg-Uranylacetate - Prec. Liquid 60 ml 2-8 C CE 60 NA NA HB017 TIBC 1 Saturation and precipitating reagents Liquid 100 t 2-8 C CE Total Iron Binding Capacity, to be used with HB

12 Enzymes Measurement Samples Number of tests per kit Code Name Method Format Packing Standard included Colorimetric Ultra-violet End-Point Kinetic Serum Plasma Whole Blood CSF T CE CYANStart CYANPro CYANExpert 130 HBE03 a-amylase CNPG3 Liquid 20 x 2 ml 2-8 C CE HBE01 Acid phosphatase Hillman Lyophilised 18 x 2 ml 2-8 C CE HBE02 Alkaline phosphatase DGKC Lyophilised 15 x 15 ml 2-8 C CE HBE10 Creatine Kinase MB Immunoinhibition Lyophilised 19 x 2,5 ml C 2-8 C CE HBEL05 Creatine Kinase MB Liquid Immunoinhibition Liquid ml C 2-8 C CE HBE04 Creatine Kinase NAC Creatine-phosphate / NAC activated Lyophilised 20 x 2,5 ml 2-8 C CE HBEL03 Creatine Kinase NAC Liquid Creatine-phosphate / NAC activated Liquid ml 2-8 C CE HBE05 g-gt carboxy Carboxy substrate Lyophilised 15 x 15 ml 2-8 C CE HBEL06 g-gt carboxy Liquid Carboxy substrate Liquid ml 2-8 C CE HBE06 GOT ast Aspartate / a-ketoglutarate IFCC Lyophilised 15 x 15 ml 2-8 C CE HBEL010 GOT ast Liquid Aspartate / a-ketoglutarate IFCC Liquid ml 2-8 C CE HBE07 GPT alt Alanine / a-ketoglutarate IFCC Lyophilised 15 x 15 ml 2-8 C CE HBEL020 GPT alt Liquid Alanine / a-ketoglutarate IFCC Liquid ml 2-8 C CE HBE08 Lactate dehydrogenase DGKC Lyophilised 20 x 3 ml 2-8 C CE HBEL04 Lactate dehydrogenase Liquid DGKC Liquid ml 2-8 C CE HBE09 Lipase Enzymatic Liquid 4 x 10 ml 2-8 C CE Lipids Measurement Samples Number of tests per kit Code Name Method Format Packing Standard included Colorimetric Ultra-violet End-Point Kinetic Serum Plasma Whole Blood CSF T CE CYANStart CYANPro CYANExpert 130 HB006 Cholesterol CHOD-POD Lyophilised 2 x 125 ml 2-8 C CE HBL010 Cholesterol Liquid CHOD-POD Liquid 2 x 125 ml 2-8 C CE HB007 Cholesterol HDL² Phosphotungstic precipitation reagent Liquid 3 x 10 ml 2-8 C CE NA HB028 Cholesterol LDL Enzymatic Liquid ml 2-8 C CE HB030 Phospholipids CHO POD Lyophilised 10 x 10 ml 2-8 C CE HB018 Total lipids Phosphovainilline Liquid 2 x 125 ml 2-8 C CE 250 NA NA HB021 Triglycerides GPO-POD Lyophilised 12 x 20 ml 2-8 C CE HBL06 Triglycerides Liquid GPO-POD Liquid 2 x 150 ml 2-8 C CE ² to be used with HB006 and HBL C for controls

13 Substrates Measurement Samples Number of tests per kit Code Name Method Format Packing Standard included Colorimetric Ultra-violet End-Point Kinetic Serum Plasma Whole Blood CSF T CE CYANStart CYANPro CYANExpert 130 HB0010 Albumin Bromocresol green Liquid 2 x 125 ml 2-25 C CE HB001 Albumin Bromocresol green Liquid 1 x 1000 ml 2-25 C CE HB0260 Bilirubin direct DMSO Liquid 2 x 125 ml 2-8 C CE HB0270 Bilirubin total DMSO Liquid 2 x 125 ml 2-8 C CE HB0020 Bilirubin total & direct DMSO Liquid 2 x 125 ml 2-8 C CE 2 x 41 2 x x 520 HB0080 Creatinine Jaffe Liquid 2 x 125 ml 2-25 C CE HB009 Glucose GOD-POD Lyophilised 2 x 125 ml 2-8 C CE HB010 Glucose GOD-POD Lyophilised 4 x 250 ml 2-8 C CE HBL04 Glucose Liquid GOD-POD Liquid 2 x 125 ml 2-8 C CE HBL05 Glucose Liquid GOD-POD Liquid 1 x 1000 ml 2-8 C CE HB011 Haemoglobin (Conc. (x50)) Drabkin Liquid 4 x 5 ml 2-8 C CE HB031 Haemoglobin Glycated A1c Ion exchange Liquid 20 t 2-25 C CE 20 NA NA HB020 Total prot. & CSF Pyrogallol red Liquid 2 x 125 ml 2-8 C CE HB0190 Total protein Biuret Liquid 2 x 125 ml 2-8 C CE HB019 Total protein Biuret Liquid 1 x 1000 ml 2-8 C CE HB029 Urea Berthelot Lyophilised 2 x 125 ml 2-8 C CE HB022 Urea Berthelot Lyophilised 4 x 250 ml 2-8 C CE HBL03 Urea Liquid Urease GLDH - UV Liquid ml 2-8 C CE HB023 Uric acid Uricase-POD Lyophilised 12 x 20 ml 2-8 C CE HB024 Uric acid Uricase-POD Lyophilised 2 x 125 ml 2-8 C CE HBL02 Uric acid Liquid Uricase-POD Liquid 2 x 150 ml 2-8 C CE For best results we recommend Cypress Diagnostics biochemistry kits. Detailed information about our reagents can be downloaded from our website: 19 20

14 Control Sera Code Name Format Packing T CE HBC08 CK (NAC & MB) control Lyophilised 4 x 2 ml 2-8 C CE HBC07 Lipid control Lyophilised 4 x 1 ml 2-8 C CE HBC04 Normal bovine sera Lyophilised 10 x 5 ml 2-8 C CE HBC01 Normal human sera Lyophilised 4 x 5 ml 2-8 C CE HBC05 Pathological bovine sera Lyophilised 10 x 5 ml 2-8 C CE HBC02 Pathological human sera Lyophilised 4 x 5 ml 2-8 C CE Calibrators Code Name Format Packing T CE HBS01 Bilirubin Total Lyophilised 3 x 2 ml 2-8 C CE HBC06 Calibrator, bovine source Lyophilised 10 x 5 ml 2-8 C CE HBC03 Calibrator, human source Lyophilised 4 x 3 ml 2-8 C CE HBS02 Haemoglobin Liquid 1 ml 2-8 C CE HBS03 HDL/LDL Calibrator Lyophilised 4 x 1 ml 2-8 C CE Hematology CYANHemato: Automatic Hematology Analyser Enjoy more convenient reporting with paper printouts and USB data transfer to your computer. Up to 30 tests/hour Turbidimetry Code Name Format Packing T CE HT001 HbA1c Turbidimetric Liquid 1 x 30 ml 2-8 C CE HT001C HbA1c Control (2 levels) Lyophilised 4 x 0,5 ml 2-8 C CE HT001S Calibrator HbA1c (4 levels) Lyophilised 4 x 0,5 ml 2-8 C CE The sample tube holder increases the user safety and convenience. The CYANHemato is a fully automated, 18 parameters, bench-top hematology cell counter. The analyzer can process 30 samples per hour in 3-part WBC differential mode. High-lights: 18 hematology parameters 3-part WBC differential Only 25 μl whole blood sample Easy to use Color LCD touch screen USB connectivity Predilution mode Automatic daily maintenance Large memory Performant QC software 21 22

15 Technical Specifications The analyzer determines the following 18 hematology parameters: WBC total white blood cell count LYM lymphocytes count MON monocytes count GRA granulocytes count LYM% lymphocytes percentage MON% monocytes percentage GRA% granulocytes percentage HGB hemoglobin RBC red blood cell count HCT hematocrit MCV mean corpuscular volume MCH mean corpuscular hemoglobin MCHC mean corpuscular hemoglobin concentration RDW red blood cell distribution width PLT platelet count PCT platelet percentage, thrombocit MPV mean platelet volume PDW platelet distribution width Sample volume: 25 μl of whole blood in normal mode 50 μl of whole blood in pre-diluted mode Measurement: Aperture diameter 70 μm (RBC, PLT, WBC) Throughput 30 tests/hour Reagent requirement: Diluent - 20l (code: CY006-R01) Lyse - 1l (code: CY006-R02) Cleaner - 1l (code: CY006-R03) Sampling: Open tube system Automatic sample rotor Multiple sample profiles Cleaning procedure of the aperture: High-voltage burn High-pressure back-flush Chemical cleaning Calibration: Automatic calibration on the basis of 1 measurement(s) Manual calibration using theoretical factors User interface: Easy-to-use Full-LCD Touch-screen External keyboard (in option, via USB) Languages: English, French, Spanish, Portuguese & Russian Memory: 1000 results, with RBC, PLT and WBC 3-part histogram Printer: Built-in printer Full report with histograms Interface via USB for HP printers Power: 110/220 Volt, 50/60Hz Advised: Electronic Stabilizer (> 1kW Power potential) No-Break Module (UPS - Uninterrupted Power Supply) Operation temperature: C Weight & dimensions: 32 x 26 x 36,5 cm (L x W x H) 12 kg Order code: CY006: CYANHemato For best results we advice the use of a roller mixer to gently mix the samples prior to analysis. Does your lab already have a roller mixer? Our distributor will be glad to tell you more about the CL007 Roller Mixer. Reagents Code Name Format Packing T CE CY006-R01 Diluent Liquid 20 l C CE CY006-R02 Lyse Liquid 1 l C CE CY006-R03 Cleaner Liquid 1 l C CE All reagents have a validity of 120 days after opening. These reagents are exclusively calibrated for the CYANHemato. Cleaners Code Name Format Packing T CE CY006-R04 Hypoclean Liquid 1 l C CE CY006-R05 Clenz Liquid 1 l C CE CY006-R06 Hypoclean CC Liquid 100 ml C CE All cleaners have a validity of 120 days after opening. Controls Touch screen and keyboard connectivity Code Name Format Packing T CE CY006-C01 Control Package Normal Liquid 6 x 2,5 ml 2-8 C CE CY006-C01A Control Vial Normal Liquid 1 x 2,5 ml 2-8 C CE CY006-C02 Control Package Low/Normal/High Liquid 18 x 2,5 ml 2-8 C CE CY006-C02A Control Vials Low/Normal/High Liquid 3 x 2,5 ml 2-8 C CE

16 Coagulation CYANCoag: Semi-Automatic Coagulation Analyser The CYANCoag is a compact and accurate coagulation analyser. Its mechanical detection system will track the developing coagulum through changes in viscosity. The measurement is, therefore, totally independent of the sample s turbidity. The measurements are started by a count-down timer avoiding the extra expenses of a start pipette. Choose for CYANCoag and get the following advantages: Works on whole blood and plasma Measures PT, APTT, & Fibrinogen Mechanical detection Results in seconds and INR Measuring volume of µl Error control Count-down start Incubator with 5 positions Micro-method: up to 50% lower reagent consumption Technical data: 1 Channel Mechanical detection Voltage 110/220V; 50/60 Hz (adaptor) Power consumption: 16 W Weight: 1,1 kg Dimensions: 11,3 x 68 x 20,7 cm (WxHxL) Order code: CY003: CYANCoag CY003-C01: Cuvettes and balls for 500 tests Extras: The CYANCoag kit includes cuvettes and balls for 500 tests Up to 60 tests/hour Reagents Code Name Method Format HC00100 HC00300 APTT (Act. Thromboplastine Time) Fibrinogen The Micro-method + 2 x more reported results Act. Cephaline, incl 2x10ml CaCl2 VonClauss method, incl 1x120 ml buffer Test medium Packing T CE Lyophilised PL 5 x 4 ml 2-8 C CE Lyophilised PL 8 x 2 ml 2-8 C CE HC00200 PT Prothrombin Time Tissue thromboplastine Lyophilised PL 4 x 5 ml 2-8 C CE Controls Code Name Method Format Test medium Packing T CE HC00500 Coagulation Control Normal + pathological Lyophilised - 4 x (1+1) ml 2-8 C CE HC00600 Calibrator Fibr/PT Fibrinogen / PT Lyophilised - 4 x 1 ml 2-8 C CE 25 26

17 Microbiology Antibiotic discs Description* Disc content Code Amikacin AK Amoxicillin AX Amoxicillin / clavulanic acid AMC Ampicillin AM Ampicillin / sulbactam SAM Azithromycin AZM Azlocillin AZL Aztreonam ATM Bacitracin B Carbencillin PY Cefaclor CEC Cefadroxil CFR Cefamandole MA Cefazolin CZ Cefepime FEP Cefixime CFM Cefoperazone CEP Cefotaxime CTX Cefoxitin FOX Cefprozil CPR Cefsulodin CFS Ceftazidime CAZ Ceftibuten CBT Ceftizoxime ZOX Ceftriaxone CRO Cefuroxime CXM Cephalexin CL Cephalothin KF Cephradine CE Chloramphenicol C Cinoxacin CIN Ciprofloxacin CIP Clarithromycin CLR Clindamycin DA Cloxacillin CX Colistin CT Doxycycline DO Erythromycin E Fosfomycin FF Furazolidone FX Description* Disc content Code Fusidic acid FA Gentamicin CN Imipenem IPM Imipenem / cilastatin IMC Kanamycin K Levofloxacin LEV Lincomycin L Lomefloxacin LOM Meropenem MEM Mezlocillin MEZ Minocycline MI Moxifloxacin MXF Nalidixic acid NA Neomycin N Netilmicin NET Nitrofurantoin F Norfloxacin NOR Novobiocin NV Ofloxacin OFX Oxacillin OX Oxolinic acid OA Oxytetracycline T Pefloxacin PEF Penicillin P Pipemidic acid PI Piperacillin PRL Piperacillin / tazobactam TPZ Polymixin B PB Rifampin RA Roxitromycin ROX Sisomycin SIS Spectinomycin SPT Spiramycin SP Streptomycin S Sulfisoxazole ST Sulphamethoxazole SMZ Teicoplanin TEC Tetracycline TE Ticarcillin TIC Ticarcillin / clavulanic acid TIM Description* Disc content Code Tobramycin TOB Trimethoprim TMP Trimethoprim / SXT sulphamethoxazole Tylosin TY Vancomycin VA *Storage: C Preferably store at -20 C before opening. All discs are CE labelled. All items are packed in 5 x 50 discs Culture media Antifungal Antibiotics* Disc content Code Amphotericin B AMB Clotrimazole CLT Econazole ECO Fluconazole FLU Griseofulvin GRS Itraconazole ITR Ketoconazole KTC Metronidazole MET Miconazole MCZ Nystatin NY Code Name Description Format Packing T CE Mueller Hinton Agar Culture media dehydrated 500 g C CE Mueller Hinton Broth Culture media dehydrated 500 g C CE 27 28

18 Stains Bacteriology Stains Code Name Detection of Packing T CE HS019 Brilliant Green Alcohol-acid resistant Mycobacteria (TB) 1000 ml C CE HS015 Carbol Fuchsin Alcohol-acid resistant Mycobacteria (TB) 1000 ml C CE HS017 Carbol Fuchsin Kinyoun Alcohol-acid resistant Mycobacteria (TB) 1000 ml C CE HS021 Carbol Gentian Violet Gram positive / negative bacteria 1000 ml C CE HS013 Crystal Violet Gram positive / negative bacteria 1000 ml C CE HS001 Gram PVP Gram positive / negative bacteria 4 x 250 ml C CE HS022 Lugol Stabilized with PVP Gram positive / negative bacteria 1000 ml C CE HS016 Methylene Blue (Kühne s) Alcohol-acid resistant Mycobacteria (TB) 1000 ml C CE HS014 Safranin Gram positive / negative bacteria 1000 ml C CE HS018 TB Decolorizer Alcohol-acid resistant Mycobacteria (TB) 1000 ml C CE HS002 TB Ziehl - Neelsen Kit Alcohol-acid resistant Mycobacteria (TB) 3 x 250 ml C CE Blood Grouping Reagents ABO grouping Code Name Method Test medium Packing T CE 401 Anti - A Slide, tube / agglutinating WB / RC 10 ml 2-8 C Anti - B Slide, tube / agglutinating WB / RC 10 ml 2-8 C Anti - AB Slide, tube / agglutinating WB / RC 10 ml 2-8 C Anti - D Slide, tube / agglutinating WB / RC 10 ml 2-8 C Anti D Blend (IgM+IgG) Slide, tube / agglutinating & Coombs WB / RC 10 ml 2-8 C S Blood grouping Kit (Anti-A, B, AB, D) Slide, tube / agglutinating WB / RC 4x10 ml 2-8 C AHG - Anti Human Globulin Tube SE / RC 10 ml 2-8 C BSA - Bovine Albumine 22% Tube SE / RC 10 ml 2-8 C BSA - Bovine Albumine 30% Tube SE / RC 10 ml 2-8 C L.I.S.S Tube RC 10 ml 2-8 C Anti-D incomplete Slide, tube / agglutinating & Coombs WB / RC 10 ml 2-8 C Negative control/diluent Slide, tube WB / RC 10 ml 2-8 C - Hematology Stains Code Name Method Packing T CE HS003 Giemsa Romanowsky stain 500 ml C CE HS005 Quick Panoptic Conc (1:10) kit Romanowsky stain 3 x 100 ml C CE HS004 May Grünwald Romanowsky stain 500 ml C CE HS023 Wright Romanowsky stain 500 ml C CE Histopathology Stains - Papanicolaou Code Name Method Packing T CE HS006 Harris Hematoxylin Dr Montalvo - Dr Meissner 500 ml C CE HS007 Orange G-6 solution Dr Montalvo - Dr Meissner 500 ml C CE HS008 Polychromic solution EA-36 Dr Montalvo - Dr Meissner 500 ml C CE HS009 Polychromic solution EA-50 Dr Montalvo - Dr Meissner 500 ml C CE Ancillary Products Code Name Method Packing T CE HS010 Hayem RBC manual counting 500 ml C CE HS012 Immersion Oil For microscopy 100 ml C - HS011 Türck WBC manual counting 500 ml C CE 29 30

19 Subtypes Code Name Method Test medium Packing T CE 420 Anti A1 Dolichos bifl. Lectin Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti C Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti c Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti C(w) Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti CDE Slide, tube / agglutinating WB / RC 10 ml 2-8 C Anti Cellano Tube / Coombs RC 5 ml 2-8 C Anti Co(b) Tube / Coombs RC 2 ml 2-8 C Anti Di(a) Tube / Coombs RC 2 ml 2-8 C Anti E Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti e Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti Fy(a) Tube / Coombs RC 5 ml 2-8 C Anti Fy(b) Tube / Coombs RC 5 ml 2-8 C Anti H (A2) Tube RC 5 ml 2-8 C Anti Jk(a) Tube / Coombs RC 5 ml 2-8 C Anti Jk(b) Tube / Coombs RC 5 ml 2-8 C Anti Kell Slide, tube / agglutinating RC / WB 5 ml 2-8 C Anti Kp(a) Tube / Coombs RC 5 ml 2-8 C Anti Kp(b) Tube / Coombs RC 5 ml 2-8 C Anti Le(a) Tube / agglutinating RC 5 ml 2-8 C Anti Le(b) Tube / agglutinating RC 5 ml 2-8 C Anti Lu(a) Tube / Coombs RC 5 ml 2-8 C Anti Lu(b) Tube / Coombs RC 5 ml 2-8 C Anti M Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti N Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti P1 Slide, tube / agglutinating WB / RC 5 ml 2-8 C Anti S Tube / Coombs RC 5 ml 2-8 C Anti s Tube / Coombs RC 5 ml 2-8 C Anti Wr(a) Tube / Coombs RC 5 ml 2-8 C Anti Xg(a) Tube / Coombs RC 2 ml 2-8 C Anti-A2 Tube / agglutinating RC 5 ml 2-8 C Anti-D incomplete Slide, tube / agglutinating & Coombs WB / RC 10 ml 2-8 C - Agglutination/Latex Kits Code Name Method Format Test medium Packing T CE ASO Agglutination test Slide SE 100 t 2-8 C CE CRP Agglutination test Slide SE 100 t 2-8 C CE hcg Agglutination test Slide UR 100 t 2-8 C CE Infectious Mononucleosis Agglutination test Slide SE 50 t 2-8 C CE RF Agglutination test Slide SE 100 t 2-8 C CE Rose Bengal Agglutination test Slide SE 50 t 2-8 C CE RPR carbon 150t Flocculation Slide SE / PL 150 t 2-8 C CE 22152S RPR carbon 5 ml Flocculation Slide SE / PL 5 ml 2-8 C CE RPR carbon 500t Flocculation Slide SE / PL 500 t 2-8 C CE TPHA Micro haemagglutination MTP SE/PL 200 t 2-8 C CE Toxo Agglutination test Slide SE 100 t 2-8 C VDRL Flocculation Slide SE / PL 1500 t 2-8 C CE Waaler Rose Haemagglutination Slide SE 50 t 2-8 C CE For best results with agglutination tests we advice to work at the ideal speed of 100 RPM. Does your rotator indicate this critical speed? Our distributor will be glad to tell you more about the CL002 Rotator

20 Rapid Tests General Format Test medium T Pregnancy Rapid Tests Format Test medium T Code Name Packing Dipstrip Card 346 Cardiac Troponin I (ctni) 25 t CE Chagas 20 t C CE 322 Chlamydia Ag 20 t (1) Dengue IgG/IgM Combo 25t CE 347 FOB Faecal Occult Blood 25 t CE 333 H. Pylori Ab 20 t CE 354 Hepatitis A Ag 20 t CE HBsAg Card 25 t /S HBsAg Strip 2 x 25 t Anti HCV Card 25 t /S Anti HCV Strip 2 x 25 t HIV 1/2 40 t Influenza A 25t (2) CE 355 Leptospira IgM 25t CE Malaria falciparum 25 t 4-28 C CE 345 Malaria Total 25 t 8-40 C CE (P.f., P.v., P.m., P.o.) 343 PSA 25 t Rubella Combo IgG/IgM 25 t Strep A 20 t (3) CE 353 Syphilis Rapid Test 50 t CE TB - tuberculosis 20 t - Serum Plasma Faeces Whole Blood Other 2-30 C 4-30 C 8-30 C C Other CE Code Name Packing Parasitic Dipstrip Card Serum Plasma 4-30 C hcg Bulk - Dipstrip bulk CE /20 hcg - Dipstrip 20 t CE /50 hcg - Dipstrip 50 t CE /100 hcg - Dipstrip 100 t CE 132-Mane hcg Manene kit - Dipstrip 25 t CE /4x25 hcg Strip Tube 25t x t CE hcg Bulk - Card bulk CE /20 hcg - Card 20 t CE /50 hcg - Card 50 t CE /100 hcg - Card 100 t CE Code Name Packing Format Test medium T CE Dipstrip Card Plasma Faeces 4-30 C C 335 Rota Kit 25 t CE 336 Adeno Kit 25 t CE 339 Crypto Kit 25 t CE 340 Leishmania Kit 25 t CE 349 Giardia kit 25 t CE CE (1) Endocervical - Urethral (2) Nasopharyngeal secretion (3) Throat swab test 33 34