Electronic Health Records Integration Workgroup. Justin Starren and Marc Williams, Co-chairs Erwin Bottinger Co-chair emeritus
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1 Electronic Health Records Integration Workgroup Justin Starren and Marc Williams, Co-chairs Erwin Bottinger Co-chair emeritus
2 Workgroup Members THANK YOU!!! Noura Abul-husn Berta Almoguera Melissa Basford Erwin Bottinger Murray Brilliant Pedro Caraballo David Carey Ariel Chandler CG Chute Jim Cimino John Connolly David Crosslin Josh Denny Kim Doheny Steve Ellis Bob Freimuth Justin Giles Adam Hardebeck John Harley Paul Harris Andrea Hartzler Max He Mike Heathcote Tim Herr Kurt Hetrick Lucia Hindorff Ingrid Holm Iyad Isseh Lynn Ivacic Jean Jenkins Hayan Jouni Joseph Kannry Jacqueline Kirby Terrie Kitchner Isaac Kohane Iftikhar Kullo Eric Larose Rongling Li Simon Lin Jennifer Madison Teri Manolio Keith Marsolo Cathy McCarty Jen McCormick Jason Napora Casey Overby Jennifer Pacheco Vivian Pan Jyoti Pathak Peggy Peissig Cassandra Perry Josh Peterson Erin Ramos Luke Rasmussen Laura Rasmussen-Torvik Marylyn Ritchie Caer Vitek Missi Rowe Aaron Scrol Brian Shirts Maureen Smith Sarah Stallings Justin Starren Gerard Tromp Chunhua Weng Ken Wiley Marc Williams Janet Williams Grant Wood Adam Wright
3 Charter The EHR Integration workgroup develops emerge II consensus and concepts for EMR integration of genomic information and clinical decision support (CDS) delivery. The workgroup delineates common and distinct approaches and challenges for EMR integration, shares best practices, addresses challenges and approaches for using whole genome/exome sequenceassociated information, establishes a dialog with EMR vendors, and supports the use and evaluation of CDS tools.
4 Updates External collaborations Publications, presentations, abstracts Infobutton Project (Scientific Presentation) CDS Repository
5 External Collaborations AMIA Genomics and Translational Bioinformatics Working Group Clinical Decision Support Consortium (hiatus) ONC S&I Health edecisions HL7 Clinical Genomics Workgroup IOM Roundtable on Translating Genomic-Based Research for Health Global Genomic Medicine Collaborative (G2MC) Global Alliance for Genomic Health (GA4GH) Liaisons with CSER, ClinGen, IGNITE Precision Medicine Initiative (Josh Denny) Clinical Pharmacogenomic Implementation Consortium Informatics Workgroup and PGRN PGx Guideline Repository IOM DIGITizE: Displaying and Integrating Genetic Information Through the EHR
6 PGRN PGx Guideline Repository Designed to archive structured (computable) guideline artifacts Structured metadata Based on the CDSC Knowledge Framework Level 1 documents linked to Level 2 & 3 artifacts Content CPIC Guidelines (Level 1, Level 2) PGRN Translational PGx Project (Level 2) ONC Standards & Interoperability Framework: Health edecisions (HeD) schema (Level 3) Initial release scheduled for July 2015 Potential synergy with emerge CDS KB Strong preference to collaborate
7 Clinical PGx Implementation Consortium (CPIC) Informatics Working Group Goal: To support the adoption of the CPIC guidelines by identifying, and resolving where possible, potential technical barriers to the implementation of the guidelines within a clinical electronic environment. Create comprehensive translation tables from genotype to phenotype to clinical recommendation for CPIC guidelines Define structure and process to efficiently develop and maintain in the most useful format(s) Term Standardization for Clinical PGx Test Results Delphi survey process Inclusion in LOINC
8 IOM DIGITizE Working on two end to end pharmacogeomics implementation use cases Abacavir and HLA-B*57:01 Azathioprine and TPMT Large and diverse group including ONC, vendors (both EHR and LIS), providers, informaticists etc. Many emerge sites involved Hope to have fully implemented CDS for these two use cases by the end of the year Identifying many issues (most of which have been encountered in emerge) If successful could dramatically lower barriers to implementation Findings from emerge have been central to this work
9 Publications AMIA 2015 Panel: Public Implementation Resources for Genomic Medicine Josh Peterson, Marc Williams, Casey Overby, Robert Freimuth, Iftikhar Kullo A Conceptual Model for Omic Data Tim Herr; accepted with revisions to Journal of Pathology Informatics Practical Considerations in Genomic Decision Support: The emerge Experience Tim Herr; accepted JPI CSER and emerge: Current and Potential State of the Display of Genetic Information in the EHR Brian Shirts; accepted to JAMIA
10 CDS Repository Develop a lightweight repository as a platform to publicly disseminate unstructured CDS artifacts from institutions with genomic medicine programs Available at: Library is filling up 31 artifacts from 9 institutions Learning series IGNITE presentations being confirmed (August) First Thursday of the month, 2-3pm CST
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17 CDSKB Acknowledgements Vanderbilt / CC Paul Harris Jacqueline Kirby Josh Peterson Benjamin Phelps Chad Lightner emerge EHRI WG IGNITE NHGRI emerge CDS KB WG Pedro Caraballo Steve Ellis Bob Freimuth Andrea Hartzler Casey Overby Peggy Peissig Ken Wiley Marc Williams
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