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PERSONAL PROFILE Dr. Manzo graduated cum laude in Dentistry (DDS) in 1997 with a thesis on occlusion and posture correlations. Since his graduation he has followed a training program focused on both traditional and lingual orthodontics. He completed his post-graduate studies in Orthodontics (MSc) with honors and he received a PhD in Oral Science at University of Naples Federico II. He is Adjunct Assistant Professor at University of Naples Federico II. He is the President of the Leading Alliance Orthodontic Society founded in 2014 during SIDO Congress. Dr Manzo received the excellence certification by the Italian Board of Orthodontics (IBO), by the European Board of Orthodontics (EBO) and by the European Board of Lingual Orthodontics (EBLO). Dr. Manzo has lectured at courses, universities and congresses throughout the world on the following topics: lingual orthodontics, straight wire and self-ligating technique, DR. torque management with variable prescriptions, finishing, VIA P.M. VERGARA 140 biomechanics, Class II malocclusions, interdisciplinary and FRATTAMAGGIORE (NAPLES) ITALY 80027 complex treatments of dental anomalies and TAD management. TEL. 0039 3925005296 Dr. Manzo has trained Italian and international doctors with 0039 0818348282 practical, in-office courses that manages with his coworkers on lingual techniques with Harmony system and on the straight PAOLO.MANZO@GMAIL.COMWWW. wire technique. He has presented several award winning STUDIOMANZO.IT scientific and clinical papers at national and international conferences and clinical practice is limited exclusively to the orthodontics and craniomandibular disorder management. Dr Manzo is a Board member of the European Federation of Orthodontics (FEO) and of the Italian Dental Association (ANDI). EDUCATION 1997 University of Naples Federico II, DDS with honors 2004 University of Naples Federico II, Master of Science in Orthodontics 2007 University of Naples Federico II, PhD (Oral Sciences) CONTINUING EDUCATION 1998 University of Naples Federico II, Wires Modeling Course 1998 University of Naples Federico II, 1st Stage Orthodontics one-year course 1999 University of Naples Federico II, 2nd Stage Orthodontics one-year course

CONTINUING EDUCATION - CONT D 2002 Invisalign Certification, Naples 2003 Lingual Orthodontics (Dr. D. Fillion) Full Immersion, Paris 2008 Clearstep Certification, EOS, Lisbon TEACHING RESPONSIBILITIES 2008-Present Adjunct Assistant Professor, Department of Orthodontics, University of Naples Federico II 2004-Present Orthodontics Postgraduate Course Clinical Instructor (Straight Wire and Low Friction Technique), Department of Orthodontics, University of Naples Federico II 2004-Present Orthodontics Postgraduate Course Clinical Instructor (Early and Functional Therapy) Department of Orthodontics, University of Naples Federico II ESTEEM INDICATORS Italian Dental Association (ANDI) Regional Continuing Education Delegate 2010- Present Coordinator of Orthodontic Training Study Group Campania (Micerium/AO), 2008 - Present President of the Scientific Committee of the 1st Congress Summit-School Gaeta (Italy), September 18-20, 2008 President of the Scientific Committee of the 2nd Congress Summit-School. Gaeta (Italy), September 25-26, 2009 Coordinator of Straight Wire National Continuing Education Group (Micerium/AO) 2010- Present PROFESSIONAL ORGANIZATIONS Member of I.B.O. (Italian Board of Orthodontics) Active member of S.I.D.O. (Italian Society of Orthodontics) Member of E.O.S. (European Orthodontic Society) Member of AIOL (Italian Association of Lingual Orthodontics) Member of ANDI (Italian Dental Association) Member of ASIO (Italian Association of Specialists in Orthodontics) Member of REDOI (Register of Italian Specialists in Orthodontics) AWARDS Award of Distinction: Paduano S, Manzo P, Tagliaferri R, Monaco M, Pellegrino G. Variazione dello spazio orofaringeo in pazienti con malocclusione scheletrica di Classe II trattati con apparecchiatura di Sander. XI Congresso Nazionale del Collegio dei Docenti, Rome (Italy) April 24, 2004 Award of Distinction: Manzo P, Baldares S, Pellegrino G, Valletta R, Tedesco A. Analisi dei rapporti dimensionali interarcata nelle malocclusioni di classe II. XIII Congresso Nazionale del Collegio dei Docenti, Rome (Italy) April 8, 2006

AWARDS CONT D Award winning: P.Leone, R.Nucera, A.Militi, A.Rapuano, P.Manzo. Espansione Mascellare Trasversale:RCT Web-based con valutazione TC-3D dello splancnocranio. XIV Congresso Nazionale del Collegio dei Docenti, Rome (Italy) April 21, 2007 Award winning: Napoli C, Nucera R, Iudicello V, Portelli M, Manzo P. Valutazione anatomofunzionale delle cavità nasali dopo espansione mascellare. XVI Congresso Nazionale del Collegio dei Docenti, Rome (Italy) April 22-24, 2009 Houston Award Selected Oral Presentation : Cioffi I, Cordasco G, Manzo P, Nucera R, Martina R. Rapid versus slow maxillary expansion: a three-dimensional randomized clinical trial. EOS Congress, June 15-19 2010, Portoroz, Slovenia Award Gold brush winning Show case : X DentalGo meeting, Naples (Italy) November 4-6, 2010 RECENT PERSONAL COURSES One-year course on: Straight wire and low-friction: the modern orthodontics evolution, Florence (Italy), 2011 2-days course on: Full immersion in orthodontic modeling: practical course, Krakow (Poland), Sept, 2010 2-days course on: Aesthetics in orthodontics and self-ligating brackets: from the diagnosis to finishing, Krakow (Poland), May 2010 One-day course on: Torque control with self-ligating brackets, XVI Dentalevante ANDI (Italian Dental Association), Bari (Italy), Nov 2010 One-day course on: Self-ligating: treatment strategies for future orthodontics, Cenacolo Odontostomatologico, Reggio Calabria (Italy), Jun 2010 One day course at 2nd stage Master Scienze Ortodontiche e Pedodontiche University of Messina, (Italy), September 12, 2009 One-day course on: Presente e futuro dell ortodonzia:come e perché le innovazioni delle sistematiche e delle tecnologie influiscono sui nostri trattamenti, AIO (National Dentists Society) Lecce (Italy), September 27, 2008 One-day course on: Sistematiche a bassa frizione:quali vantaggi?, University La Sapienza of Rome (Italy), September 13, 2007 One-day course: Sistemi e biomeccaniche low-friction: quali vantaggi?, Post-graduate in Orthodontics Programme University of Palermo (Italy), May 9, 2007 RECENT INVITED LECTURES Torque control with self-ligating brackets: easyself system, XXII Italian Orthodontic Society International Congress (SIDO), Micerium-AO/Stand presentation, Florence (Italy) November 26, 2010 Quando iniziare il trattamento ortodontico, Course: L ortodonzia in chiave intercettiva, The Medical and Dental Association Naples (Italy), October 29, 2010 L approccio interdisciplinare al paziente ortodontico, Regional Workshop Italian Orthodontic Society (SIDO), Napoli (Italy), October 22, 2010

RECENT INVITED LECTURES - CONT D Controllo del torque con attacchi Self-Ligating, Congresso Nazionale del Collegio dei Docenti in Odontoiatria, Chieti (Italy), April 21-23, 2010 Innovation in orthodontics, Micerium-A/O Workshop, Sharm El Sheik (Egypt), March 14-21, 2010 Results of a RCT evaluating palatal expansion effects, Agrigento (Italy), November 27-28, 2009 Easy self: an innovation in torque control with self-ligating brackets, XXI Italian Orthodontic Society International Congress (SIDO), Micerium-AO/Stand presentation, Rome (Italy), November 5-7, 2009. L estetica in ortodonzia e l ortodonzia estetica: apparecchiature invisibili e risultati visibili, Regional Workshop Italian Orthodontic Society (SIDO), Vietri sul mare (Italy) October 10, 2009 Innovazione e tecnologia nelle biomeccaniche straight wire. Il controllo differenziato della frizione, Congresso Nazionale dei Docenti di Discipline Odontostomatoloigiche e Chirurgia Maxillo Facciale, Rome (Italy), April 22-24, 2009 Lectio Magistralis: Terapia ortognatodontica dell età evolutiva, University Cattolica del Sacro Cuore of Rome, Post-graduate in Orthodontics Programme, Rome (Italy), January 29, 2009 Workshop: Come cambia il trattamento con auto leganti:gestione clinica ancoraggio e contenzione. General Regional Hospital F.Miulli, Acquaviva Delle Fonti (BA) Italy 7 June 2008 Controllo tridimensionale delle arcate con i sistemi a bassa frizione, XV Congresso Nazionale del Collegio dei Docenti in Odontoiatria, Rome (Italy), April 16-19, 2008 Iter diagnostico e terapeutico nel paziente in crescita di II classe, 2nd Young Researchers in Orthodontics Meeting, University Cattolica del Sacro Cuore of Rome, (Italy), December 12, 2007 I dispositivi di correzione delle II classi scheletriche, Congress ItinerANTLO, Paestum (Italy) November 30 December 1, 2007 Biomeccanica e applicazioni cliniche delle sistematiche a bassa frizione, Course ANDI (Italian Dental Association), Vibo Valentia (Italy), November 17, 2007 Workshop: Innovations in Dentistry, University of Messina, (Italy), October 12-13, 2007 Terapia funzionale e correzione scheletrica: illusione o realtà?, 1st Young Researchers in Orthodontics Meeting, University Cattolica del Sacro Cuore of Rome, (Italy), December 12, 2006. PUBLICATIONS IN PEER-REVIEWED JOURNALS AND MEETING ABSTRACTS Michelotti A, Buonocore G, Manzo P, Pellegrino G, Farella M. Dental occlusion and posture: an overview. Accepted to be published in 2011 in Progress in Orthodontics Michelotti A, Buonocore G, Leone P, Manzo P. Masticatory system, TMJ disorders and postural alterations: a critical review. M. Ortod. 2008, 1, 1-9 Michelotti A, Manzo P, Farella M, Martina R. Occlusion and posture: is there evidence of correlation?, Min. Stom. 1999;48:525-34 Cioffi I, Cordasco G, Manzo P, Nucera R, Martina R. Rapid versus slow maxillary expansion: a three-dimensional randomized clinical trial. Eur J Orthod 2010;32:e7

PUBLICATIONS IN PEER-REVIEWED JOURNALS AND MEETING ABSTRACTS Miano L, Manzo P, Borrelli A, Macrì LA, Deli R. Effects of functional therapy in Petrovic s Rotational Types. Eur J Orthod 2008;30:e126 Nucera R, Manzo P, Militi A, Portelli M, Matarese G. Comparison of the effects of rapid and slow maxillary expansion: a computer tomographic pilot study. Eur J Orthod 2008;30:e136 Michelotti A, Buonocore G, Manzo P. Is unilateral posterior Crossbite associate with leg length inequality? Eur J Orthod 2006;28:e234 Valletta R, Pezzella E, Baldares S, Paduano S, Manzo P. Shear bond strength of a new orthodontic bracket s base design. Eur J Orthod 2006;28:e234 Manzo P, Pellegrino G, La Rocca G. Dentoskeletal effects of the functional therapy with a bite jumping appliance. Eur J Orthod 2006;28:e98 Leone P, Manzo P, Michelotti A. Masticatory system and postural alterations: a critical review Italian Orthodontic Society International Congress (SIDO), Florence (Italy), November 24-27, 2010 Manzo P, D Antò V, Leone P. Efficiency in torque managment: easyself-ligating system. Italian Orthodontic Society International Congress (SIDO), Florence (Italy), November 24-27, 2010 Manzo P, Nucera R, Cioffi I. Rapid vs Slow maxillary expansion: A randomized controlled trial. Italian Orthodontic Society International Congress (SIDO), Florence (Italy), November 24-27, 2010 Manzo P. THE CONTEMPORARY CANONS OF FEMALE FACIAL ATTRACTIVENESS: Open and cross bite case presentation. MOIP-Italian Orthodontic Society International Congress (SIDO) Viareggio, Italy 14-15 May 2010 Manzo P. THE CONTEMPORARY CANONS OF FEMALE FACIAL ATTRACTIVENESS: Four bicuspid extraction case presentation. MOIP-Italian Orthodontic Society International Congress (SIDO) Viareggio, Italy 14-15 May 2010 Manzo P. THE CONTEMPORARY CANONS OF FEMALE FACIAL ATTRACTIVENESS: II class div 2 malocclusion case presentation. MOIP-Italian Orthodontic Society International Congress (SIDO) Viareggio, Italy 14-15 May 2010 Manzo P. THE CONTEMPORARY CANONS OF FEMALE FACIAL ATTRACTIVENESS: I class malocclusion case presentation. MOIP-Italian Orthodontic Society International Congress (SIDO) Viareggio, Italy 14-15 May 2010 Martina R, Manzo P, Cioffi I, La Rocca G, Tagliaferri R. The efficacy of treatment timing of class II malocclusion, American Association of Orthodontists 109th Annual Congress Boston, May 1-5, 2009 Paduano S, Uomo R, Silva R, Valletta R, Manzo P: Facial attractiveness evaluation of treated and untreated class II profile America Association of Orthodontists 109TH Annual Congress, Boston, 1-5 May 2009 Manzo P, Tagliaferri R, Pellegrino G. Easy self: innovazioni nel controllo del torque con attacchi self-ligating. Italian Orthodontic Society International Congress (SIDO), Rome (Italy), November 5-7, 2009 D Antò V, Manzo P, Valletta R. L utilizzo della microscopia a forza atomica (AFM) nello studio della rugosità dei fili ortodontici.italian Orthodontic Society International Congress (SIDO), Rome (Italy), November 5-7, 2009

PUBLICATIONS IN PEER-REVIEWED JOURNALS AND MEETING ABSTRACTS Tagliaferri R, Uomo R, Manzo P. Il controllo del torque incisivo nelle malocclusioni di Classe II divisione 2 con l utilizzo di brackets self-ligating. Italian Orthodontic Society International Congress (SIDO), Rome (Italy), November 5-7, 2009 Valletta R, D Antò V, Ametrano G, Manzo P, Paduano S, Martina R. The surface roughness of orthodontic wires: an AFM study. Joint Meeting of the Continental European (CED), the Scandinavian (NOF) and Israeli (ID) Divisions of IADR. Munich (Germany), September 9-12, 2009 Manzo P, Albano A, Del Vecchio G. Fiberglass reinforced composite (frc) vs conventional bonded retainers: a clinical evaluation. Italian Orthodontic Society International Congress (SIDO), Florence (Italy), November 20-22, 2008 Manzo P. Low friction tecnique: how to carry out effective and efficient orthodontic treatment. Italian Orthodontic Society International Congress (SIDO), Naples (Italy), October 24-27, 2007 Manzo P, Baldares S, Pellegrino G. Transverse discrepancy and dental anterior variables in class II malocclusion. Congress of the European Orthodontic Society, Berlin (Germany), June 19-24, 2007 Valletta R, Merone G, Paduano S, Manzo P, Martina R. Biomechanical evaluation of a new design of the base bracket: R-System. Congress of the European Orthodontic Society, Berlin (Germany), June 19-24, 2007 Manzo P, Leone P, Baldares S, Pellegrino G, Valletta R. Transverse Discrepancy and Dental Anterior Variables in Class II malocclusion. Congress of the European Orthodontic Society, Berlin (Germany), June 19-24, 2007 Manzo P, Tagliaferri R. Self-ligating brackets: biomechanics and clinical improvements. Italian Orthodontic Society International Congress (SIDO), Florence (Italy), November 15-18, 2006